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Network neighborhood for query Sequence : ASTL_HUMAN

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ASTL_HUMAN
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ASTL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	252	Target Neighborhood Hits	252	Shared Neighborhood Hits	252
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_MOUSE
θ value	1.7349e-152 (rank : 2)	NC score	0.937536 (rank : 2)
Query Neighborhood Hits	252	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

MEP1B_HUMAN
θ value	3.06405e-32 (rank : 3)	NC score	0.742025 (rank : 3)
Query Neighborhood Hits	252	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	2.86786e-30 (rank : 4)	NC score	0.733407 (rank : 4)
Query Neighborhood Hits	252	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

BMP1_MOUSE
θ value	1.4233e-29 (rank : 5)	NC score	0.479487 (rank : 11)
Query Neighborhood Hits	252	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
θ value	1.85889e-29 (rank : 6)	NC score	0.481713 (rank : 8)
Query Neighborhood Hits	252	Target Neighborhood Hits	233	Shared Neighborhood Hits	18
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_HUMAN
θ value	5.40856e-29 (rank : 7)	NC score	0.482394 (rank : 7)
Query Neighborhood Hits	252	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	5.40856e-29 (rank : 8)	NC score	0.480293 (rank : 10)
Query Neighborhood Hits	252	Target Neighborhood Hits	240	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
θ value	3.50572e-28 (rank : 9)	NC score	0.480934 (rank : 9)
Query Neighborhood Hits	252	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	7.80994e-28 (rank : 10)	NC score	0.479229 (rank : 12)
Query Neighborhood Hits	252	Target Neighborhood Hits	237	Shared Neighborhood Hits	18
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

MEP1A_HUMAN
θ value	1.33217e-27 (rank : 11)	NC score	0.705515 (rank : 5)
Query Neighborhood Hits	252	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	1.33217e-27 (rank : 12)	NC score	0.699158 (rank : 6)
Query Neighborhood Hits	252	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

NFAC1_HUMAN
θ value	0.00134147 (rank : 13)	NC score	0.078555 (rank : 83)
Query Neighborhood Hits	252	Target Neighborhood Hits	312	Shared Neighborhood Hits	50
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

CS007_HUMAN
θ value	0.00390308 (rank : 14)	NC score	0.070403 (rank : 107)
Query Neighborhood Hits	252	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CSKI2_HUMAN
θ value	0.00509761 (rank : 15)	NC score	0.046847 (rank : 215)
Query Neighborhood Hits	252	Target Neighborhood Hits	747	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CS016_HUMAN
θ value	0.00665767 (rank : 16)	NC score	0.104160 (rank : 53)
Query Neighborhood Hits	252	Target Neighborhood Hits	310	Shared Neighborhood Hits	41
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SYN1_HUMAN
θ value	0.00869519 (rank : 17)	NC score	0.084320 (rank : 76)
Query Neighborhood Hits	252	Target Neighborhood Hits	419	Shared Neighborhood Hits	60
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

IF35_MOUSE
θ value	0.0113563 (rank : 18)	NC score	0.071893 (rank : 103)
Query Neighborhood Hits	252	Target Neighborhood Hits	210	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

LEG3_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.057154 (rank : 161)
Query Neighborhood Hits	252	Target Neighborhood Hits	124	Shared Neighborhood Hits	21
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

NFAC1_MOUSE
θ value	0.0148317 (rank : 20)	NC score	0.069513 (rank : 111)
Query Neighborhood Hits	252	Target Neighborhood Hits	92	Shared Neighborhood Hits	19
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SYNJ1_HUMAN
θ value	0.0330416 (rank : 21)	NC score	0.061778 (rank : 141)
Query Neighborhood Hits	252	Target Neighborhood Hits	498	Shared Neighborhood Hits	63
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CO2A1_HUMAN
θ value	0.0431538 (rank : 22)	NC score	0.062698 (rank : 132)
Query Neighborhood Hits	252	Target Neighborhood Hits	486	Shared Neighborhood Hits	77
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

MUC13_MOUSE
θ value	0.0431538 (rank : 23)	NC score	0.095406 (rank : 68)
Query Neighborhood Hits	252	Target Neighborhood Hits	447	Shared Neighborhood Hits	42
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SYN1_MOUSE
θ value	0.0563607 (rank : 24)	NC score	0.078090 (rank : 85)
Query Neighborhood Hits	252	Target Neighborhood Hits	363	Shared Neighborhood Hits	52
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CN032_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.070023 (rank : 108)
Query Neighborhood Hits	252	Target Neighborhood Hits	233	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

IRS2_MOUSE
θ value	0.0736092 (rank : 26)	NC score	0.068990 (rank : 115)
Query Neighborhood Hits	252	Target Neighborhood Hits	248	Shared Neighborhood Hits	38
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

JPH2_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.088095 (rank : 74)
Query Neighborhood Hits	252	Target Neighborhood Hits	639	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K1802_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.078683 (rank : 81)
Query Neighborhood Hits	252	Target Neighborhood Hits	1596	Shared Neighborhood Hits	126
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MLL3_MOUSE
θ value	0.0736092 (rank : 29)	NC score	0.075120 (rank : 93)
Query Neighborhood Hits	252	Target Neighborhood Hits	1399	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CIC_MOUSE
θ value	0.0961366 (rank : 30)	NC score	0.072195 (rank : 101)
Query Neighborhood Hits	252	Target Neighborhood Hits	742	Shared Neighborhood Hits	92
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MAST1_HUMAN
θ value	0.0961366 (rank : 31)	NC score	0.013750 (rank : 321)
Query Neighborhood Hits	252	Target Neighborhood Hits	1146	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PCLO_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.089436 (rank : 72)
Query Neighborhood Hits	252	Target Neighborhood Hits	2275	Shared Neighborhood Hits	158
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

VASP_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.070626 (rank : 106)
Query Neighborhood Hits	252	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ATX2_MOUSE
θ value	0.125558 (rank : 34)	NC score	0.055396 (rank : 178)
Query Neighborhood Hits	252	Target Neighborhood Hits	445	Shared Neighborhood Hits	54
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BSN_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.095105 (rank : 69)
Query Neighborhood Hits	252	Target Neighborhood Hits	1537	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CIC_HUMAN
θ value	0.125558 (rank : 36)	NC score	0.083285 (rank : 78)
Query Neighborhood Hits	252	Target Neighborhood Hits	992	Shared Neighborhood Hits	123
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MAVS_HUMAN
θ value	0.125558 (rank : 37)	NC score	0.072060 (rank : 102)
Query Neighborhood Hits	252	Target Neighborhood Hits	271	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

TMPSD_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.010266 (rank : 342)
Query Neighborhood Hits	252	Target Neighborhood Hits	333	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

JPH2_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.056287 (rank : 170)
Query Neighborhood Hits	252	Target Neighborhood Hits	279	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

DOT1L_HUMAN
θ value	0.21417 (rank : 40)	NC score	0.075037 (rank : 94)
Query Neighborhood Hits	252	Target Neighborhood Hits	660	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ARMX2_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.033169 (rank : 263)
Query Neighborhood Hits	252	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

IRS2_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.062577 (rank : 133)
Query Neighborhood Hits	252	Target Neighborhood Hits	262	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

PCLO_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.077206 (rank : 88)
Query Neighborhood Hits	252	Target Neighborhood Hits	2046	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RTN4_MOUSE
θ value	0.279714 (rank : 44)	NC score	0.039304 (rank : 236)
Query Neighborhood Hits	252	Target Neighborhood Hits	341	Shared Neighborhood Hits	29
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

TAF4_HUMAN
θ value	0.279714 (rank : 45)	NC score	0.077333 (rank : 86)
Query Neighborhood Hits	252	Target Neighborhood Hits	687	Shared Neighborhood Hits	72
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CSKI2_MOUSE
θ value	0.365318 (rank : 46)	NC score	0.044885 (rank : 222)
Query Neighborhood Hits	252	Target Neighborhood Hits	812	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

BSN_MOUSE
θ value	0.47712 (rank : 47)	NC score	0.109726 (rank : 48)
Query Neighborhood Hits	252	Target Neighborhood Hits	2057	Shared Neighborhood Hits	165
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO2A1_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.059008 (rank : 153)
Query Neighborhood Hits	252	Target Neighborhood Hits	483	Shared Neighborhood Hits	70
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

ELN_HUMAN
θ value	0.47712 (rank : 49)	NC score	0.069145 (rank : 113)
Query Neighborhood Hits	252	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

ELN_MOUSE
θ value	0.47712 (rank : 50)	NC score	0.062353 (rank : 136)
Query Neighborhood Hits	252	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

FXL19_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.037547 (rank : 247)
Query Neighborhood Hits	252	Target Neighborhood Hits	147	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GSCR1_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.072658 (rank : 100)
Query Neighborhood Hits	252	Target Neighborhood Hits	674	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SELO_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.037399 (rank : 248)
Query Neighborhood Hits	252	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVL4, Q8WUI0	Gene names	SELO
Domain Architecture
Description	Selenoprotein O.

SSFA2_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.056242 (rank : 171)
Query Neighborhood Hits	252	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q922B9, Q8VEF7	Gene names	Ssfa2
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2.

SSH1_MOUSE
θ value	0.47712 (rank : 55)	NC score	0.018970 (rank : 305)
Query Neighborhood Hits	252	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

VASP_MOUSE
θ value	0.47712 (rank : 56)	NC score	0.062244 (rank : 137)
Query Neighborhood Hits	252	Target Neighborhood Hits	195	Shared Neighborhood Hits	30
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ZDHC1_MOUSE
θ value	0.47712 (rank : 57)	NC score	0.023630 (rank : 285)
Query Neighborhood Hits	252	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0N9, Q8BJ24	Gene names	Zdhhc1
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1).

ADA19_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.014225 (rank : 318)
Query Neighborhood Hits	252	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ARID2_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.044227 (rank : 224)
Query Neighborhood Hits	252	Target Neighborhood Hits	302	Shared Neighborhood Hits	28
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

CO9A1_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.048927 (rank : 212)
Query Neighborhood Hits	252	Target Neighborhood Hits	420	Shared Neighborhood Hits	62
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CUTL1_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.012634 (rank : 328)
Query Neighborhood Hits	252	Target Neighborhood Hits	1574	Shared Neighborhood Hits	49
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

FXL19_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.044212 (rank : 226)
Query Neighborhood Hits	252	Target Neighborhood Hits	217	Shared Neighborhood Hits	33
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

ICAL_MOUSE
θ value	0.62314 (rank : 63)	NC score	0.038257 (rank : 242)
Query Neighborhood Hits	252	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

KLF15_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.003836 (rank : 377)
Query Neighborhood Hits	252	Target Neighborhood Hits	720	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UIH9	Gene names	KLF15, KKLF
Domain Architecture
Description	Krueppel-like factor 15 (Kidney-enriched krueppel-like factor).

SYNJ1_MOUSE
θ value	0.62314 (rank : 65)	NC score	0.059880 (rank : 151)
Query Neighborhood Hits	252	Target Neighborhood Hits	516	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

UBE4B_HUMAN
θ value	0.62314 (rank : 66)	NC score	0.039000 (rank : 238)
Query Neighborhood Hits	252	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

BAT3_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.080682 (rank : 79)
Query Neighborhood Hits	252	Target Neighborhood Hits	518	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CABIN_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.064005 (rank : 128)
Query Neighborhood Hits	252	Target Neighborhood Hits	490	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CAC1H_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.021563 (rank : 296)
Query Neighborhood Hits	252	Target Neighborhood Hits	230	Shared Neighborhood Hits	29
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

DEN1A_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.030878 (rank : 266)
Query Neighborhood Hits	252	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

M3K12_MOUSE
θ value	0.813845 (rank : 71)	NC score	0.011080 (rank : 336)
Query Neighborhood Hits	252	Target Neighborhood Hits	957	Shared Neighborhood Hits	37
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MBD5_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.053449 (rank : 190)
Query Neighborhood Hits	252	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

NKX12_MOUSE
θ value	0.813845 (rank : 73)	NC score	0.011545 (rank : 333)
Query Neighborhood Hits	252	Target Neighborhood Hits	332	Shared Neighborhood Hits	10
SwissProt Accessions	P42580, Q9JHF2, Q9JKW5, Q9JKW6, Q9JKW9, Q9JKX0, Q9JKX1	Gene names	Nkx1-2, Nkx1.1, Sax1
Domain Architecture
Description	NK1 transcription factor-related protein 2 (Homeobox protein SAX-1) (NKX-1.1).

PABP2_MOUSE
θ value	0.813845 (rank : 74)	NC score	0.036717 (rank : 251)
Query Neighborhood Hits	252	Target Neighborhood Hits	214	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

SHAN1_HUMAN
θ value	0.813845 (rank : 75)	NC score	0.038157 (rank : 243)
Query Neighborhood Hits	252	Target Neighborhood Hits	1041	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TBX2_HUMAN
θ value	0.813845 (rank : 76)	NC score	0.015487 (rank : 312)
Query Neighborhood Hits	252	Target Neighborhood Hits	195	Shared Neighborhood Hits	28
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

CO3A1_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.053661 (rank : 189)
Query Neighborhood Hits	252	Target Neighborhood Hits	466	Shared Neighborhood Hits	56
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

GGN_MOUSE
θ value	1.06291 (rank : 78)	NC score	0.054095 (rank : 186)
Query Neighborhood Hits	252	Target Neighborhood Hits	311	Shared Neighborhood Hits	40
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HCN2_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.025497 (rank : 278)
Query Neighborhood Hits	252	Target Neighborhood Hits	369	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

MUCDL_HUMAN
θ value	1.06291 (rank : 80)	NC score	0.060611 (rank : 148)
Query Neighborhood Hits	252	Target Neighborhood Hits	777	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PABP2_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.036171 (rank : 252)
Query Neighborhood Hits	252	Target Neighborhood Hits	212	Shared Neighborhood Hits	12
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PRG4_HUMAN
θ value	1.06291 (rank : 82)	NC score	0.046448 (rank : 218)
Query Neighborhood Hits	252	Target Neighborhood Hits	764	Shared Neighborhood Hits	58
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RERE_MOUSE
θ value	1.06291 (rank : 83)	NC score	0.046602 (rank : 217)
Query Neighborhood Hits	252	Target Neighborhood Hits	785	Shared Neighborhood Hits	64
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RP3A_MOUSE
θ value	1.06291 (rank : 84)	NC score	0.032667 (rank : 264)
Query Neighborhood Hits	252	Target Neighborhood Hits	510	Shared Neighborhood Hits	69
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

BAT3_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.074262 (rank : 96)
Query Neighborhood Hits	252	Target Neighborhood Hits	490	Shared Neighborhood Hits	81
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BRSK1_HUMAN
θ value	1.38821 (rank : 86)	NC score	0.007451 (rank : 356)
Query Neighborhood Hits	252	Target Neighborhood Hits	942	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

CAC1B_MOUSE
θ value	1.38821 (rank : 87)	NC score	0.023661 (rank : 284)
Query Neighborhood Hits	252	Target Neighborhood Hits	351	Shared Neighborhood Hits	40
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CO9A1_MOUSE
θ value	1.38821 (rank : 88)	NC score	0.053878 (rank : 187)
Query Neighborhood Hits	252	Target Neighborhood Hits	477	Shared Neighborhood Hits	81
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CSF1_HUMAN
θ value	1.38821 (rank : 89)	NC score	0.069946 (rank : 109)
Query Neighborhood Hits	252	Target Neighborhood Hits	258	Shared Neighborhood Hits	53
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

DYN1_MOUSE
θ value	1.38821 (rank : 90)	NC score	0.024444 (rank : 281)
Query Neighborhood Hits	252	Target Neighborhood Hits	168	Shared Neighborhood Hits	31
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

EPN1_MOUSE
θ value	1.38821 (rank : 91)	NC score	0.034878 (rank : 257)
Query Neighborhood Hits	252	Target Neighborhood Hits	240	Shared Neighborhood Hits	36
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

FOG1_MOUSE
θ value	1.38821 (rank : 92)	NC score	0.023439 (rank : 286)
Query Neighborhood Hits	252	Target Neighborhood Hits	1237	Shared Neighborhood Hits	99
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

JPH1_HUMAN
θ value	1.38821 (rank : 93)	NC score	0.038847 (rank : 240)
Query Neighborhood Hits	252	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HDC5	Gene names	JPH1, JP1
Domain Architecture	No domain graphic available
Description	Junctophilin-1 (Junctophilin type 1) (JP-1).

M3K12_HUMAN
θ value	1.38821 (rank : 94)	NC score	0.010435 (rank : 341)
Query Neighborhood Hits	252	Target Neighborhood Hits	940	Shared Neighborhood Hits	31
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MLL2_HUMAN
θ value	1.38821 (rank : 95)	NC score	0.061189 (rank : 144)
Query Neighborhood Hits	252	Target Neighborhood Hits	1788	Shared Neighborhood Hits	125
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NOTC2_MOUSE
θ value	1.38821 (rank : 96)	NC score	0.042827 (rank : 229)
Query Neighborhood Hits	252	Target Neighborhood Hits	1069	Shared Neighborhood Hits	58
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PHX2B_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.016715 (rank : 308)
Query Neighborhood Hits	252	Target Neighborhood Hits	407	Shared Neighborhood Hits	25
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.016715 (rank : 309)
Query Neighborhood Hits	252	Target Neighborhood Hits	407	Shared Neighborhood Hits	25
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

RPTOR_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.028379 (rank : 271)
Query Neighborhood Hits	252	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SRRM1_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.055221 (rank : 179)
Query Neighborhood Hits	252	Target Neighborhood Hits	690	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM2_MOUSE
θ value	1.38821 (rank : 101)	NC score	0.064792 (rank : 127)
Query Neighborhood Hits	252	Target Neighborhood Hits	1470	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WNK2_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.021658 (rank : 295)
Query Neighborhood Hits	252	Target Neighborhood Hits	1407	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

BAD_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.033392 (rank : 262)
Query Neighborhood Hits	252	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q92934, O14803	Gene names	BAD, BBC6, BCL2L8
Domain Architecture	No domain graphic available
Description	Bcl2 antagonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl- XL/Bcl-2-associated death promoter) (Bcl-2-like 8 protein).

BAT2_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.076626 (rank : 90)
Query Neighborhood Hits	252	Target Neighborhood Hits	931	Shared Neighborhood Hits	113
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

C1QRF_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.035440 (rank : 254)
Query Neighborhood Hits	252	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	O88992	Gene names	C1ql1, C1qrf, Crf
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

GA2L1_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.029684 (rank : 267)
Query Neighborhood Hits	252	Target Neighborhood Hits	177	Shared Neighborhood Hits	32
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

K1802_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.048435 (rank : 213)
Query Neighborhood Hits	252	Target Neighborhood Hits	1378	Shared Neighborhood Hits	99
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAST1_MOUSE
θ value	1.81305 (rank : 108)	NC score	0.012582 (rank : 329)
Query Neighborhood Hits	252	Target Neighborhood Hits	1123	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MDC1_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.076518 (rank : 91)
Query Neighborhood Hits	252	Target Neighborhood Hits	1446	Shared Neighborhood Hits	110
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

WASP_MOUSE
θ value	1.81305 (rank : 110)	NC score	0.039053 (rank : 237)
Query Neighborhood Hits	252	Target Neighborhood Hits	223	Shared Neighborhood Hits	32
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

CAC1B_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.019350 (rank : 303)
Query Neighborhood Hits	252	Target Neighborhood Hits	257	Shared Neighborhood Hits	22
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CO3A1_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.052970 (rank : 193)
Query Neighborhood Hits	252	Target Neighborhood Hits	452	Shared Neighborhood Hits	54
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A1_MOUSE
θ value	2.36792 (rank : 113)	NC score	0.044221 (rank : 225)
Query Neighborhood Hits	252	Target Neighborhood Hits	450	Shared Neighborhood Hits	70
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COGA1_HUMAN
θ value	2.36792 (rank : 114)	NC score	0.043536 (rank : 228)
Query Neighborhood Hits	252	Target Neighborhood Hits	345	Shared Neighborhood Hits	45
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CRSP2_HUMAN
θ value	2.36792 (rank : 115)	NC score	0.054619 (rank : 183)
Query Neighborhood Hits	252	Target Neighborhood Hits	380	Shared Neighborhood Hits	59
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

ENAH_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.056653 (rank : 166)
Query Neighborhood Hits	252	Target Neighborhood Hits	919	Shared Neighborhood Hits	59
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FMN2_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.028828 (rank : 268)
Query Neighborhood Hits	252	Target Neighborhood Hits	484	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GATA4_HUMAN
θ value	2.36792 (rank : 118)	NC score	0.012468 (rank : 330)
Query Neighborhood Hits	252	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P43694	Gene names	GATA4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

LTBP2_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.051741 (rank : 202)
Query Neighborhood Hits	252	Target Neighborhood Hits	552	Shared Neighborhood Hits	28
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

M3K10_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.007907 (rank : 351)
Query Neighborhood Hits	252	Target Neighborhood Hits	1071	Shared Neighborhood Hits	25
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MAML2_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.035671 (rank : 253)
Query Neighborhood Hits	252	Target Neighborhood Hits	360	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MK07_HUMAN
θ value	2.36792 (rank : 122)	NC score	0.009921 (rank : 344)
Query Neighborhood Hits	252	Target Neighborhood Hits	1087	Shared Neighborhood Hits	52
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

NACAM_MOUSE
θ value	2.36792 (rank : 123)	NC score	0.089343 (rank : 73)
Query Neighborhood Hits	252	Target Neighborhood Hits	1866	Shared Neighborhood Hits	147
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NOTC2_HUMAN
θ value	2.36792 (rank : 124)	NC score	0.045466 (rank : 219)
Query Neighborhood Hits	252	Target Neighborhood Hits	1113	Shared Neighborhood Hits	77
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RABX5_HUMAN
θ value	2.36792 (rank : 125)	NC score	0.019627 (rank : 300)
Query Neighborhood Hits	252	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

RECQ4_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.020996 (rank : 297)
Query Neighborhood Hits	252	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RUNX3_MOUSE
θ value	2.36792 (rank : 127)	NC score	0.024420 (rank : 282)
Query Neighborhood Hits	252	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SI1L3_HUMAN
θ value	2.36792 (rank : 128)	NC score	0.025120 (rank : 279)
Query Neighborhood Hits	252	Target Neighborhood Hits	305	Shared Neighborhood Hits	42
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SSFA2_HUMAN
θ value	2.36792 (rank : 129)	NC score	0.047661 (rank : 214)
Query Neighborhood Hits	252	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P28290, Q96E36	Gene names	SSFA2, CS1
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2 (Cleavage signal-1 protein) (CS-1).

TLE1_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.022126 (rank : 293)
Query Neighborhood Hits	252	Target Neighborhood Hits	491	Shared Neighborhood Hits	59
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ABL1_MOUSE
θ value	3.0926 (rank : 131)	NC score	0.007192 (rank : 359)
Query Neighborhood Hits	252	Target Neighborhood Hits	1178	Shared Neighborhood Hits	45
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BASP_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.044599 (rank : 223)
Query Neighborhood Hits	252	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

C1QRF_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.034165 (rank : 260)
Query Neighborhood Hits	252	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	O75973	Gene names	C1QL1, C1QRF, CRF
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

CD2L5_MOUSE
θ value	3.0926 (rank : 134)	NC score	0.006084 (rank : 365)
Query Neighborhood Hits	252	Target Neighborhood Hits	1011	Shared Neighborhood Hits	31
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CO7A1_HUMAN
θ value	3.0926 (rank : 135)	NC score	0.037934 (rank : 245)
Query Neighborhood Hits	252	Target Neighborhood Hits	807	Shared Neighborhood Hits	86
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

EPN1_HUMAN
θ value	3.0926 (rank : 136)	NC score	0.033856 (rank : 261)
Query Neighborhood Hits	252	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

FOXQ1_HUMAN
θ value	3.0926 (rank : 137)	NC score	0.011093 (rank : 335)
Query Neighborhood Hits	252	Target Neighborhood Hits	115	Shared Neighborhood Hits	12
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

HUWE1_MOUSE
θ value	3.0926 (rank : 138)	NC score	0.013675 (rank : 322)
Query Neighborhood Hits	252	Target Neighborhood Hits	406	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

KLF15_MOUSE
θ value	3.0926 (rank : 139)	NC score	0.002059 (rank : 379)
Query Neighborhood Hits	252	Target Neighborhood Hits	707	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EPW2, Q3UQB0	Gene names	Klf15, Cklf
Domain Architecture
Description	Krueppel-like factor 15 (Cardiovascular Krueppel-like factor).

MKL2_HUMAN
θ value	3.0926 (rank : 140)	NC score	0.021708 (rank : 294)
Query Neighborhood Hits	252	Target Neighborhood Hits	274	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

NOTC1_HUMAN
θ value	3.0926 (rank : 141)	NC score	0.040424 (rank : 232)
Query Neighborhood Hits	252	Target Neighborhood Hits	906	Shared Neighborhood Hits	31
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
θ value	3.0926 (rank : 142)	NC score	0.040857 (rank : 231)
Query Neighborhood Hits	252	Target Neighborhood Hits	975	Shared Neighborhood Hits	45
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PGCA_MOUSE
θ value	3.0926 (rank : 143)	NC score	0.018513 (rank : 307)
Query Neighborhood Hits	252	Target Neighborhood Hits	643	Shared Neighborhood Hits	41
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PHC2_MOUSE
θ value	3.0926 (rank : 144)	NC score	0.025992 (rank : 276)
Query Neighborhood Hits	252	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PLK3_HUMAN
θ value	3.0926 (rank : 145)	NC score	0.005854 (rank : 367)
Query Neighborhood Hits	252	Target Neighborhood Hits	865	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H4B4, Q15767, Q96CV1	Gene names	PLK3, CNK, FNK, PRK
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase) (Proliferation-related kinase).

PYGO2_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.040046 (rank : 235)
Query Neighborhood Hits	252	Target Neighborhood Hits	189	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

TAU_MOUSE
θ value	3.0926 (rank : 147)	NC score	0.060550 (rank : 149)
Query Neighborhood Hits	252	Target Neighborhood Hits	502	Shared Neighborhood Hits	79
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TTBK1_HUMAN
θ value	3.0926 (rank : 148)	NC score	0.016446 (rank : 310)
Query Neighborhood Hits	252	Target Neighborhood Hits	1058	Shared Neighborhood Hits	59
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ANR43_HUMAN
θ value	4.03905 (rank : 149)	NC score	0.019506 (rank : 301)
Query Neighborhood Hits	252	Target Neighborhood Hits	209	Shared Neighborhood Hits	12
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANXA7_HUMAN
θ value	4.03905 (rank : 150)	NC score	0.012832 (rank : 326)
Query Neighborhood Hits	252	Target Neighborhood Hits	168	Shared Neighborhood Hits	20
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

ARI1B_HUMAN
θ value	4.03905 (rank : 151)	NC score	0.043794 (rank : 227)
Query Neighborhood Hits	252	Target Neighborhood Hits	567	Shared Neighborhood Hits	75
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CO1A1_MOUSE
θ value	4.03905 (rank : 152)	NC score	0.050576 (rank : 211)
Query Neighborhood Hits	252	Target Neighborhood Hits	457	Shared Neighborhood Hits	60
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COE4_HUMAN
θ value	4.03905 (rank : 153)	NC score	0.010262 (rank : 343)
Query Neighborhood Hits	252	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQW3, Q5JY53, Q9NUB6, Q9P2A6	Gene names	EBF4, COE4, KIAA1442
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

CSKI1_HUMAN
θ value	4.03905 (rank : 154)	NC score	0.041244 (rank : 230)
Query Neighborhood Hits	252	Target Neighborhood Hits	997	Shared Neighborhood Hits	95
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DIDO1_HUMAN
θ value	4.03905 (rank : 155)	NC score	0.070890 (rank : 105)
Query Neighborhood Hits	252	Target Neighborhood Hits	960	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ENAH_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.034633 (rank : 259)
Query Neighborhood Hits	252	Target Neighborhood Hits	784	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FOXF2_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.009020 (rank : 346)
Query Neighborhood Hits	252	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

IRAK1_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.009388 (rank : 345)
Query Neighborhood Hits	252	Target Neighborhood Hits	784	Shared Neighborhood Hits	24
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRX2_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.013376 (rank : 324)
Query Neighborhood Hits	252	Target Neighborhood Hits	358	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

M3K4_MOUSE
θ value	4.03905 (rank : 160)	NC score	0.007712 (rank : 353)
Query Neighborhood Hits	252	Target Neighborhood Hits	924	Shared Neighborhood Hits	29
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

PO121_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.038963 (rank : 239)
Query Neighborhood Hits	252	Target Neighborhood Hits	345	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RIMB1_HUMAN
θ value	4.03905 (rank : 162)	NC score	0.027089 (rank : 273)
Query Neighborhood Hits	252	Target Neighborhood Hits	1479	Shared Neighborhood Hits	86
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SALL3_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.008666 (rank : 350)
Query Neighborhood Hits	252	Target Neighborhood Hits	1066	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SEN34_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.024572 (rank : 280)
Query Neighborhood Hits	252	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

SFPQ_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.031645 (rank : 265)
Query Neighborhood Hits	252	Target Neighborhood Hits	986	Shared Neighborhood Hits	71
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFR16_HUMAN
θ value	4.03905 (rank : 166)	NC score	0.023383 (rank : 288)
Query Neighborhood Hits	252	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N2M8, O96026, Q6UW71, Q96DX2	Gene names	SFRS16, SWAP2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2).

SMRC2_MOUSE
θ value	4.03905 (rank : 167)	NC score	0.022347 (rank : 291)
Query Neighborhood Hits	252	Target Neighborhood Hits	487	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SN_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.004784 (rank : 371)
Query Neighborhood Hits	252	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

SRBP1_HUMAN
θ value	4.03905 (rank : 169)	NC score	0.028753 (rank : 269)
Query Neighborhood Hits	252	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TAU_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.060671 (rank : 147)
Query Neighborhood Hits	252	Target Neighborhood Hits	448	Shared Neighborhood Hits	68
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TIF1B_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.013973 (rank : 320)
Query Neighborhood Hits	252	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TLE1_HUMAN
θ value	4.03905 (rank : 172)	NC score	0.019382 (rank : 302)
Query Neighborhood Hits	252	Target Neighborhood Hits	485	Shared Neighborhood Hits	50
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TNC6B_HUMAN
θ value	4.03905 (rank : 173)	NC score	0.022292 (rank : 292)
Query Neighborhood Hits	252	Target Neighborhood Hits	256	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

WASL_MOUSE
θ value	4.03905 (rank : 174)	NC score	0.036810 (rank : 250)
Query Neighborhood Hits	252	Target Neighborhood Hits	339	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WNK4_HUMAN
θ value	4.03905 (rank : 175)	NC score	0.014597 (rank : 316)
Query Neighborhood Hits	252	Target Neighborhood Hits	1043	Shared Neighborhood Hits	48
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZN408_HUMAN
θ value	4.03905 (rank : 176)	NC score	-0.001704 (rank : 382)
Query Neighborhood Hits	252	Target Neighborhood Hits	775	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

ARAF_HUMAN
θ value	5.27518 (rank : 177)	NC score	0.007463 (rank : 355)
Query Neighborhood Hits	252	Target Neighborhood Hits	924	Shared Neighborhood Hits	32
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ATF6B_MOUSE
θ value	5.27518 (rank : 178)	NC score	0.015297 (rank : 313)
Query Neighborhood Hits	252	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

AZI1_MOUSE
θ value	5.27518 (rank : 179)	NC score	0.005312 (rank : 369)
Query Neighborhood Hits	252	Target Neighborhood Hits	990	Shared Neighborhood Hits	23
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CO4A6_HUMAN
θ value	5.27518 (rank : 180)	NC score	0.038745 (rank : 241)
Query Neighborhood Hits	252	Target Neighborhood Hits	318	Shared Neighborhood Hits	42
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CPSF6_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.045266 (rank : 220)
Query Neighborhood Hits	252	Target Neighborhood Hits	359	Shared Neighborhood Hits	47
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	5.27518 (rank : 182)	NC score	0.045240 (rank : 221)
Query Neighborhood Hits	252	Target Neighborhood Hits	356	Shared Neighborhood Hits	47
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

DYN1_HUMAN
θ value	5.27518 (rank : 183)	NC score	0.025664 (rank : 277)
Query Neighborhood Hits	252	Target Neighborhood Hits	216	Shared Neighborhood Hits	41
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

EP400_MOUSE
θ value	5.27518 (rank : 184)	NC score	0.022517 (rank : 290)
Query Neighborhood Hits	252	Target Neighborhood Hits	592	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FOXD2_HUMAN
θ value	5.27518 (rank : 185)	NC score	0.007155 (rank : 361)
Query Neighborhood Hits	252	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

HES6_HUMAN
θ value	5.27518 (rank : 186)	NC score	0.014655 (rank : 315)
Query Neighborhood Hits	252	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

LAP2_MOUSE
θ value	5.27518 (rank : 187)	NC score	0.003896 (rank : 376)
Query Neighborhood Hits	252	Target Neighborhood Hits	482	Shared Neighborhood Hits	14
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LIPA3_HUMAN
θ value	5.27518 (rank : 188)	NC score	0.007281 (rank : 357)
Query Neighborhood Hits	252	Target Neighborhood Hits	828	Shared Neighborhood Hits	17
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MLL3_HUMAN
θ value	5.27518 (rank : 189)	NC score	0.069346 (rank : 112)
Query Neighborhood Hits	252	Target Neighborhood Hits	1644	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PRP2_MOUSE
θ value	5.27518 (rank : 190)	NC score	0.062205 (rank : 139)
Query Neighborhood Hits	252	Target Neighborhood Hits	347	Shared Neighborhood Hits	50
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RAD17_MOUSE
θ value	5.27518 (rank : 191)	NC score	0.014458 (rank : 317)
Query Neighborhood Hits	252	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NXW6, O88934, O89024	Gene names	Rad17
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17.

SMRD3_HUMAN
θ value	5.27518 (rank : 192)	NC score	0.010898 (rank : 338)
Query Neighborhood Hits	252	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q6STE5, Q75MJ2, Q75MR8, Q92926, Q9BUH1	Gene names	SMARCD3, BAF60C
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C).

SPEG_HUMAN
θ value	5.27518 (rank : 193)	NC score	0.013394 (rank : 323)
Query Neighborhood Hits	252	Target Neighborhood Hits	1762	Shared Neighborhood Hits	103
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRBP1_MOUSE
θ value	5.27518 (rank : 194)	NC score	0.035412 (rank : 255)
Query Neighborhood Hits	252	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRRM1_MOUSE
θ value	5.27518 (rank : 195)	NC score	0.062219 (rank : 138)
Query Neighborhood Hits	252	Target Neighborhood Hits	966	Shared Neighborhood Hits	84
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TCOF_HUMAN
θ value	5.27518 (rank : 196)	NC score	0.037942 (rank : 244)
Query Neighborhood Hits	252	Target Neighborhood Hits	543	Shared Neighborhood Hits	48
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	5.27518 (rank : 197)	NC score	0.040268 (rank : 234)
Query Neighborhood Hits	252	Target Neighborhood Hits	471	Shared Neighborhood Hits	41
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TENS1_HUMAN
θ value	5.27518 (rank : 198)	NC score	0.026595 (rank : 275)
Query Neighborhood Hits	252	Target Neighborhood Hits	400	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TGON2_HUMAN
θ value	5.27518 (rank : 199)	NC score	0.051921 (rank : 200)
Query Neighborhood Hits	252	Target Neighborhood Hits	1037	Shared Neighborhood Hits	82
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

WBS14_MOUSE
θ value	5.27518 (rank : 200)	NC score	0.023383 (rank : 289)
Query Neighborhood Hits	252	Target Neighborhood Hits	171	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ZN516_HUMAN
θ value	5.27518 (rank : 201)	NC score	0.004540 (rank : 372)
Query Neighborhood Hits	252	Target Neighborhood Hits	854	Shared Neighborhood Hits	41
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

AAK1_HUMAN
θ value	6.88961 (rank : 202)	NC score	0.012925 (rank : 325)
Query Neighborhood Hits	252	Target Neighborhood Hits	1077	Shared Neighborhood Hits	64
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ADRM1_MOUSE
θ value	6.88961 (rank : 203)	NC score	0.024227 (rank : 283)
Query Neighborhood Hits	252	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

ANDR_HUMAN
θ value	6.88961 (rank : 204)	NC score	0.002638 (rank : 378)
Query Neighborhood Hits	252	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ARX_HUMAN
θ value	6.88961 (rank : 205)	NC score	0.007160 (rank : 360)
Query Neighborhood Hits	252	Target Neighborhood Hits	401	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

BAT2_MOUSE
θ value	6.88961 (rank : 206)	NC score	0.071578 (rank : 104)
Query Neighborhood Hits	252	Target Neighborhood Hits	947	Shared Neighborhood Hits	111
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO8A1_HUMAN
θ value	6.88961 (rank : 207)	NC score	0.035200 (rank : 256)
Query Neighborhood Hits	252	Target Neighborhood Hits	288	Shared Neighborhood Hits	35
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

CSTF2_MOUSE
θ value	6.88961 (rank : 208)	NC score	0.007090 (rank : 363)
Query Neighborhood Hits	252	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

DDX24_HUMAN
θ value	6.88961 (rank : 209)	NC score	0.005390 (rank : 368)
Query Neighborhood Hits	252	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

HCFC1_MOUSE
θ value	6.88961 (rank : 210)	NC score	0.019124 (rank : 304)
Query Neighborhood Hits	252	Target Neighborhood Hits	348	Shared Neighborhood Hits	30
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HNRPL_HUMAN
θ value	6.88961 (rank : 211)	NC score	0.008829 (rank : 347)
Query Neighborhood Hits	252	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P14866, Q9H3P3	Gene names	HNRPL
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein L (hnRNP L).

IGF1R_MOUSE
θ value	6.88961 (rank : 212)	NC score	0.004004 (rank : 375)
Query Neighborhood Hits	252	Target Neighborhood Hits	973	Shared Neighborhood Hits	23
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LAP4_MOUSE
θ value	6.88961 (rank : 213)	NC score	0.004534 (rank : 373)
Query Neighborhood Hits	252	Target Neighborhood Hits	590	Shared Neighborhood Hits	21
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LIPA3_MOUSE
θ value	6.88961 (rank : 214)	NC score	0.008742 (rank : 348)
Query Neighborhood Hits	252	Target Neighborhood Hits	636	Shared Neighborhood Hits	15
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LPIN3_MOUSE
θ value	6.88961 (rank : 215)	NC score	0.007876 (rank : 352)
Query Neighborhood Hits	252	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

MBD6_HUMAN
θ value	6.88961 (rank : 216)	NC score	0.051331 (rank : 204)
Query Neighborhood Hits	252	Target Neighborhood Hits	349	Shared Neighborhood Hits	40
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

OSBP2_HUMAN
θ value	6.88961 (rank : 217)	NC score	0.007538 (rank : 354)
Query Neighborhood Hits	252	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

PHC3_MOUSE
θ value	6.88961 (rank : 218)	NC score	0.020948 (rank : 298)
Query Neighborhood Hits	252	Target Neighborhood Hits	194	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

RBM12_MOUSE
θ value	6.88961 (rank : 219)	NC score	0.028603 (rank : 270)
Query Neighborhood Hits	252	Target Neighborhood Hits	313	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RPTOR_MOUSE
θ value	6.88961 (rank : 220)	NC score	0.023432 (rank : 287)
Query Neighborhood Hits	252	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SOX15_HUMAN
θ value	6.88961 (rank : 221)	NC score	0.012464 (rank : 331)
Query Neighborhood Hits	252	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SRRM2_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.051095 (rank : 207)
Query Neighborhood Hits	252	Target Neighborhood Hits	1296	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

T22D4_HUMAN
θ value	6.88961 (rank : 223)	NC score	0.055484 (rank : 177)
Query Neighborhood Hits	252	Target Neighborhood Hits	403	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TMM28_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.019906 (rank : 299)
Query Neighborhood Hits	252	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	O75949	Gene names	TMEM28, TED
Domain Architecture	No domain graphic available
Description	Transmembrane protein 28 (TED protein).

ZEP1_MOUSE
θ value	6.88961 (rank : 225)	NC score	0.010657 (rank : 340)
Query Neighborhood Hits	252	Target Neighborhood Hits	1063	Shared Neighborhood Hits	55
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZN341_HUMAN
θ value	6.88961 (rank : 226)	NC score	-0.000794 (rank : 381)
Query Neighborhood Hits	252	Target Neighborhood Hits	803	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ADA2A_MOUSE
θ value	8.99809 (rank : 227)	NC score	-0.002924 (rank : 383)
Query Neighborhood Hits	252	Target Neighborhood Hits	900	Shared Neighborhood Hits	11
SwissProt Accessions	Q01338	Gene names	Adra2a
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR).

ADA2B_MOUSE
θ value	8.99809 (rank : 228)	NC score	-0.004328 (rank : 384)
Query Neighborhood Hits	252	Target Neighborhood Hits	891	Shared Neighborhood Hits	3
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

AIM1_HUMAN
θ value	8.99809 (rank : 229)	NC score	0.014223 (rank : 319)
Query Neighborhood Hits	252	Target Neighborhood Hits	247	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

ANR50_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.012426 (rank : 332)
Query Neighborhood Hits	252	Target Neighborhood Hits	361	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

B4GT1_MOUSE
θ value	8.99809 (rank : 231)	NC score	0.005914 (rank : 366)
Query Neighborhood Hits	252	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

BAI1_MOUSE
θ value	8.99809 (rank : 232)	NC score	0.004149 (rank : 374)
Query Neighborhood Hits	252	Target Neighborhood Hits	340	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BC11B_HUMAN
θ value	8.99809 (rank : 233)	NC score	-0.000272 (rank : 380)
Query Neighborhood Hits	252	Target Neighborhood Hits	761	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0K0, Q9H162	Gene names	BCL11B, CTIP2, RIT1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (hRit1) (COUP-TF-interacting protein 2).

BHLH8_HUMAN
θ value	8.99809 (rank : 234)	NC score	0.005137 (rank : 370)
Query Neighborhood Hits	252	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

CCNK_MOUSE
θ value	8.99809 (rank : 235)	NC score	0.027915 (rank : 272)
Query Neighborhood Hits	252	Target Neighborhood Hits	350	Shared Neighborhood Hits	32
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CNKR1_HUMAN
θ value	8.99809 (rank : 236)	NC score	0.012744 (rank : 327)
Query Neighborhood Hits	252	Target Neighborhood Hits	154	Shared Neighborhood Hits	13
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CO1A2_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.046691 (rank : 216)
Query Neighborhood Hits	252	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

COAA1_HUMAN
θ value	8.99809 (rank : 238)	NC score	0.034665 (rank : 258)
Query Neighborhood Hits	252	Target Neighborhood Hits	316	Shared Neighborhood Hits	38
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

DIAP1_MOUSE
θ value	8.99809 (rank : 239)	NC score	0.015065 (rank : 314)
Query Neighborhood Hits	252	Target Neighborhood Hits	839	Shared Neighborhood Hits	37
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

GCNL2_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.010894 (rank : 339)
Query Neighborhood Hits	252	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

HXA2_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.006334 (rank : 364)
Query Neighborhood Hits	252	Target Neighborhood Hits	370	Shared Neighborhood Hits	21
SwissProt Accessions	O43364	Gene names	HOXA2
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-A2.

HXD3_HUMAN
θ value	8.99809 (rank : 242)	NC score	0.008690 (rank : 349)
Query Neighborhood Hits	252	Target Neighborhood Hits	433	Shared Neighborhood Hits	27
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

HXD3_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.007141 (rank : 362)
Query Neighborhood Hits	252	Target Neighborhood Hits	435	Shared Neighborhood Hits	19
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

LBXCO_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.018681 (rank : 306)
Query Neighborhood Hits	252	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

LYOX_MOUSE
θ value	8.99809 (rank : 245)	NC score	0.007200 (rank : 358)
Query Neighborhood Hits	252	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P28301	Gene names	Lox, Rrg
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase) (RAS excision protein).

MBRL_MOUSE
θ value	8.99809 (rank : 246)	NC score	0.011411 (rank : 334)
Query Neighborhood Hits	252	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIV2, Q68EE1, Q6KAN7, Q7TS84, Q8CIV1, Q99K29	Gene names	ORF61
Domain Architecture	No domain graphic available
Description	Membralin.

PP4R1_MOUSE
θ value	8.99809 (rank : 247)	NC score	0.010978 (rank : 337)
Query Neighborhood Hits	252	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

RERE_HUMAN
θ value	8.99809 (rank : 248)	NC score	0.040352 (rank : 233)
Query Neighborhood Hits	252	Target Neighborhood Hits	779	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SET1A_HUMAN
θ value	8.99809 (rank : 249)	NC score	0.037757 (rank : 246)
Query Neighborhood Hits	252	Target Neighborhood Hits	690	Shared Neighborhood Hits	58
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SFR15_HUMAN
θ value	8.99809 (rank : 250)	NC score	0.026639 (rank : 274)
Query Neighborhood Hits	252	Target Neighborhood Hits	368	Shared Neighborhood Hits	28
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

TNKS1_HUMAN
θ value	8.99809 (rank : 251)	NC score	0.015603 (rank : 311)
Query Neighborhood Hits	252	Target Neighborhood Hits	477	Shared Neighborhood Hits	31
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ZIM10_MOUSE
θ value	8.99809 (rank : 252)	NC score	0.036921 (rank : 249)
Query Neighborhood Hits	252	Target Neighborhood Hits	430	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ATRN_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.110825 (rank : 46)
Query Neighborhood Hits	252	Target Neighborhood Hits	525	Shared Neighborhood Hits	16
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.108526 (rank : 51)
Query Neighborhood Hits	252	Target Neighborhood Hits	519	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BCL9_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.072673 (rank : 99)
Query Neighborhood Hits	252	Target Neighborhood Hits	1008	Shared Neighborhood Hits	127
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.061064 (rank : 145)
Query Neighborhood Hits	252	Target Neighborhood Hits	770	Shared Neighborhood Hits	106
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

C1QR1_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.066405 (rank : 125)
Query Neighborhood Hits	252	Target Neighborhood Hits	342	Shared Neighborhood Hits	15
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.103709 (rank : 55)
Query Neighborhood Hits	252	Target Neighborhood Hits	379	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.102348 (rank : 57)
Query Neighborhood Hits	252	Target Neighborhood Hits	380	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.106552 (rank : 52)
Query Neighborhood Hits	252	Target Neighborhood Hits	364	Shared Neighborhood Hits	12
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.101078 (rank : 62)
Query Neighborhood Hits	252	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CD248_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.077002 (rank : 89)
Query Neighborhood Hits	252	Target Neighborhood Hits	679	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.073424 (rank : 97)
Query Neighborhood Hits	252	Target Neighborhood Hits	578	Shared Neighborhood Hits	55
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CEL_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.055713 (rank : 175)
Query Neighborhood Hits	252	Target Neighborhood Hits	896	Shared Neighborhood Hits	117
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CLC14_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.058895 (rank : 155)
Query Neighborhood Hits	252	Target Neighborhood Hits	143	Shared Neighborhood Hits	14
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.056721 (rank : 164)
Query Neighborhood Hits	252	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CO5A2_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.057144 (rank : 162)
Query Neighborhood Hits	252	Target Neighborhood Hits	760	Shared Neighborhood Hits	103
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CS1A_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.102224 (rank : 58)
Query Neighborhood Hits	252	Target Neighborhood Hits	360	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.101957 (rank : 59)
Query Neighborhood Hits	252	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSMD1_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.149160 (rank : 38)
Query Neighborhood Hits	252	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.147459 (rank : 40)
Query Neighborhood Hits	252	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.152916 (rank : 37)
Query Neighborhood Hits	252	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.148535 (rank : 39)
Query Neighborhood Hits	252	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSPG5_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.056298 (rank : 169)
Query Neighborhood Hits	252	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CSPG5_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.054455 (rank : 184)
Query Neighborhood Hits	252	Target Neighborhood Hits	211	Shared Neighborhood Hits	33
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CUBN_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.154095 (rank : 36)
Query Neighborhood Hits	252	Target Neighborhood Hits	482	Shared Neighborhood Hits	15
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.155184 (rank : 35)
Query Neighborhood Hits	252	Target Neighborhood Hits	477	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.161075 (rank : 32)
Query Neighborhood Hits	252	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.155210 (rank : 34)
Query Neighborhood Hits	252	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.100387 (rank : 64)
Query Neighborhood Hits	252	Target Neighborhood Hits	110	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.120031 (rank : 44)
Query Neighborhood Hits	252	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.114582 (rank : 45)
Query Neighborhood Hits	252	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.110344 (rank : 47)
Query Neighborhood Hits	252	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DMBT1_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.134116 (rank : 43)
Query Neighborhood Hits	252	Target Neighborhood Hits	152	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.165454 (rank : 29)
Query Neighborhood Hits	252	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

EGFL7_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.083387 (rank : 77)
Query Neighborhood Hits	252	Target Neighborhood Hits	325	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.054966 (rank : 181)
Query Neighborhood Hits	252	Target Neighborhood Hits	287	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.052416 (rank : 197)
Query Neighborhood Hits	252	Target Neighborhood Hits	270	Shared Neighborhood Hits	12
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.055920 (rank : 174)
Query Neighborhood Hits	252	Target Neighborhood Hits	266	Shared Neighborhood Hits	12
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGF_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.053837 (rank : 188)
Query Neighborhood Hits	252	Target Neighborhood Hits	358	Shared Neighborhood Hits	15
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ENTK_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.068858 (rank : 116)
Query Neighborhood Hits	252	Target Neighborhood Hits	310	Shared Neighborhood Hits	11
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.075507 (rank : 92)
Query Neighborhood Hits	252	Target Neighborhood Hits	338	Shared Neighborhood Hits	12
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FBLN2_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.051231 (rank : 206)
Query Neighborhood Hits	252	Target Neighborhood Hits	392	Shared Neighborhood Hits	21
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.051074 (rank : 208)
Query Neighborhood Hits	252	Target Neighborhood Hits	505	Shared Neighborhood Hits	35
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.052169 (rank : 199)
Query Neighborhood Hits	252	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN5_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.061229 (rank : 143)
Query Neighborhood Hits	252	Target Neighborhood Hits	329	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.058994 (rank : 154)
Query Neighborhood Hits	252	Target Neighborhood Hits	317	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.059951 (rank : 150)
Query Neighborhood Hits	252	Target Neighborhood Hits	557	Shared Neighborhood Hits	17
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.061890 (rank : 140)
Query Neighborhood Hits	252	Target Neighborhood Hits	563	Shared Neighborhood Hits	18
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.057023 (rank : 163)
Query Neighborhood Hits	252	Target Neighborhood Hits	560	Shared Neighborhood Hits	21
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.056077 (rank : 172)
Query Neighborhood Hits	252	Target Neighborhood Hits	549	Shared Neighborhood Hits	19
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.058352 (rank : 157)
Query Neighborhood Hits	252	Target Neighborhood Hits	543	Shared Neighborhood Hits	18
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.051024 (rank : 209)
Query Neighborhood Hits	252	Target Neighborhood Hits	348	Shared Neighborhood Hits	14
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP126_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.101139 (rank : 61)
Query Neighborhood Hits	252	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GRIN1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.069736 (rank : 110)
Query Neighborhood Hits	252	Target Neighborhood Hits	681	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

KREM1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.090701 (rank : 71)
Query Neighborhood Hits	252	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.079455 (rank : 80)
Query Neighborhood Hits	252	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.104017 (rank : 54)
Query Neighborhood Hits	252	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.096971 (rank : 66)
Query Neighborhood Hits	252	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LRP12_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.142409 (rank : 42)
Query Neighborhood Hits	252	Target Neighborhood Hits	205	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.142861 (rank : 41)
Query Neighborhood Hits	252	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.109055 (rank : 50)
Query Neighborhood Hits	252	Target Neighborhood Hits	280	Shared Neighborhood Hits	32
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LTB1L_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.053209 (rank : 191)
Query Neighborhood Hits	252	Target Neighborhood Hits	553	Shared Neighborhood Hits	37
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.055921 (rank : 173)
Query Neighborhood Hits	252	Target Neighborhood Hits	514	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.052697 (rank : 195)
Query Neighborhood Hits	252	Target Neighborhood Hits	502	Shared Neighborhood Hits	31
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.055649 (rank : 176)
Query Neighborhood Hits	252	Target Neighborhood Hits	479	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.063000 (rank : 131)
Query Neighborhood Hits	252	Target Neighborhood Hits	617	Shared Neighborhood Hits	41
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.055120 (rank : 180)
Query Neighborhood Hits	252	Target Neighborhood Hits	502	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.069029 (rank : 114)
Query Neighborhood Hits	252	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MAGE1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.074460 (rank : 95)
Query Neighborhood Hits	252	Target Neighborhood Hits	1389	Shared Neighborhood Hits	161
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAMC2_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.078671 (rank : 82)
Query Neighborhood Hits	252	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.086269 (rank : 75)
Query Neighborhood Hits	252	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MASP1_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.103527 (rank : 56)
Query Neighborhood Hits	252	Target Neighborhood Hits	369	Shared Neighborhood Hits	12
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.101840 (rank : 60)
Query Neighborhood Hits	252	Target Neighborhood Hits	364	Shared Neighborhood Hits	12
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.101073 (rank : 63)
Query Neighborhood Hits	252	Target Neighborhood Hits	364	Shared Neighborhood Hits	12
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.099978 (rank : 65)
Query Neighborhood Hits	252	Target Neighborhood Hits	382	Shared Neighborhood Hits	12
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN1_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.056704 (rank : 165)
Query Neighborhood Hits	252	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.058415 (rank : 156)
Query Neighborhood Hits	252	Target Neighborhood Hits	186	Shared Neighborhood Hits	13
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.065097 (rank : 126)
Query Neighborhood Hits	252	Target Neighborhood Hits	365	Shared Neighborhood Hits	16
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.067839 (rank : 119)
Query Neighborhood Hits	252	Target Neighborhood Hits	356	Shared Neighborhood Hits	15
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.057706 (rank : 158)
Query Neighborhood Hits	252	Target Neighborhood Hits	287	Shared Neighborhood Hits	13
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.051638 (rank : 203)
Query Neighborhood Hits	252	Target Neighborhood Hits	277	Shared Neighborhood Hits	13
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MDC1_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.067342 (rank : 122)
Query Neighborhood Hits	252	Target Neighborhood Hits	998	Shared Neighborhood Hits	99
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MDGA1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.052991 (rank : 192)
Query Neighborhood Hits	252	Target Neighborhood Hits	358	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MEGF6_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.056460 (rank : 168)
Query Neighborhood Hits	252	Target Neighborhood Hits	671	Shared Neighborhood Hits	19
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MFRP_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.178442 (rank : 25)
Query Neighborhood Hits	252	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.174771 (rank : 26)
Query Neighborhood Hits	252	Target Neighborhood Hits	166	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MISS_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.057292 (rank : 160)
Query Neighborhood Hits	252	Target Neighborhood Hits	444	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MUC1_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.109541 (rank : 49)
Query Neighborhood Hits	252	Target Neighborhood Hits	975	Shared Neighborhood Hits	141
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.077217 (rank : 87)
Query Neighborhood Hits	252	Target Neighborhood Hits	1202	Shared Neighborhood Hits	137
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.062449 (rank : 135)
Query Neighborhood Hits	252	Target Neighborhood Hits	1076	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.183728 (rank : 22)
Query Neighborhood Hits	252	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.182777 (rank : 23)
Query Neighborhood Hits	252	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.184580 (rank : 21)
Query Neighborhood Hits	252	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.185238 (rank : 20)
Query Neighborhood Hits	252	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NFH_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.057412 (rank : 159)
Query Neighborhood Hits	252	Target Neighborhood Hits	2247	Shared Neighborhood Hits	148
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NRP1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.185627 (rank : 19)
Query Neighborhood Hits	252	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.187352 (rank : 18)
Query Neighborhood Hits	252	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.173271 (rank : 27)
Query Neighborhood Hits	252	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.164162 (rank : 30)
Query Neighborhood Hits	252	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

OGFR_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.096845 (rank : 67)
Query Neighborhood Hits	252	Target Neighborhood Hits	1582	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OGFR_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.052336 (rank : 198)
Query Neighborhood Hits	252	Target Neighborhood Hits	584	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PCOC1_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.210689 (rank : 13)
Query Neighborhood Hits	252	Target Neighborhood Hits	146	Shared Neighborhood Hits	18
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.209768 (rank : 14)
Query Neighborhood Hits	252	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.206003 (rank : 16)
Query Neighborhood Hits	252	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.207793 (rank : 15)
Query Neighborhood Hits	252	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.181676 (rank : 24)
Query Neighborhood Hits	252	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.192171 (rank : 17)
Query Neighborhood Hits	252	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PHXR5_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.067147 (rank : 123)
Query Neighborhood Hits	252	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PI5PA_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.067516 (rank : 121)
Query Neighborhood Hits	252	Target Neighborhood Hits	749	Shared Neighborhood Hits	121
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PROS_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.068170 (rank : 118)
Query Neighborhood Hits	252	Target Neighborhood Hits	340	Shared Neighborhood Hits	17
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.061699 (rank : 142)
Query Neighborhood Hits	252	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.051298 (rank : 205)
Query Neighborhood Hits	252	Target Neighborhood Hits	410	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRRT3_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.091635 (rank : 70)
Query Neighborhood Hits	252	Target Neighborhood Hits	998	Shared Neighborhood Hits	129
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PSL1_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.052775 (rank : 194)
Query Neighborhood Hits	252	Target Neighborhood Hits	650	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RGS3_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.051890 (rank : 201)
Query Neighborhood Hits	252	Target Neighborhood Hits	1375	Shared Neighborhood Hits	134
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.072688 (rank : 98)
Query Neighborhood Hits	252	Target Neighborhood Hits	1621	Shared Neighborhood Hits	160
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SC24C_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.056542 (rank : 167)
Query Neighborhood Hits	252	Target Neighborhood Hits	662	Shared Neighborhood Hits	109
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SCUB3_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.066928 (rank : 124)
Query Neighborhood Hits	252	Target Neighborhood Hits	428	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.067831 (rank : 120)
Query Neighborhood Hits	252	Target Neighborhood Hits	442	Shared Neighborhood Hits	11
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SELPL_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.054886 (rank : 182)
Query Neighborhood Hits	252	Target Neighborhood Hits	588	Shared Neighborhood Hits	73
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.169410 (rank : 28)
Query Neighborhood Hits	252	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SNPC4_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.050915 (rank : 210)
Query Neighborhood Hits	252	Target Neighborhood Hits	589	Shared Neighborhood Hits	97
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SON_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.078321 (rank : 84)
Query Neighborhood Hits	252	Target Neighborhood Hits	1568	Shared Neighborhood Hits	143
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.052531 (rank : 196)
Query Neighborhood Hits	252	Target Neighborhood Hits	957	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SSBP4_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.068687 (rank : 117)
Query Neighborhood Hits	252	Target Neighborhood Hits	753	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ST14_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.062450 (rank : 134)
Query Neighborhood Hits	252	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.060806 (rank : 146)
Query Neighborhood Hits	252	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TRAF4_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.059766 (rank : 152)
Query Neighborhood Hits	252	Target Neighborhood Hits	373	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.063384 (rank : 129)
Query Neighborhood Hits	252	Target Neighborhood Hits	338	Shared Neighborhood Hits	6
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TSG6_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.162260 (rank : 31)
Query Neighborhood Hits	252	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.160210 (rank : 33)
Query Neighborhood Hits	252	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

UROL1_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.054207 (rank : 185)
Query Neighborhood Hits	252	Target Neighborhood Hits	235	Shared Neighborhood Hits	18
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ZN385_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.063195 (rank : 130)
Query Neighborhood Hits	252	Target Neighborhood Hits	614	Shared Neighborhood Hits	107
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

Hits sorted by NC score

ASTL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	252	Target Neighborhood Hits	252	Shared Neighborhood Hits	252
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_MOUSE
NC score	0.937536 (rank : 2)	θ value	1.7349e-152 (rank : 2)
Query Neighborhood Hits	252	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

MEP1B_HUMAN
NC score	0.742025 (rank : 3)	θ value	3.06405e-32 (rank : 3)
Query Neighborhood Hits	252	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
NC score	0.733407 (rank : 4)	θ value	2.86786e-30 (rank : 4)
Query Neighborhood Hits	252	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MEP1A_HUMAN
NC score	0.705515 (rank : 5)	θ value	1.33217e-27 (rank : 11)
Query Neighborhood Hits	252	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
NC score	0.699158 (rank : 6)	θ value	1.33217e-27 (rank : 12)
Query Neighborhood Hits	252	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

TLL2_HUMAN
NC score	0.482394 (rank : 7)	θ value	5.40856e-29 (rank : 7)
Query Neighborhood Hits	252	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_HUMAN
NC score	0.481713 (rank : 8)	θ value	1.85889e-29 (rank : 6)
Query Neighborhood Hits	252	Target Neighborhood Hits	233	Shared Neighborhood Hits	18
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_HUMAN
NC score	0.480934 (rank : 9)	θ value	3.50572e-28 (rank : 9)
Query Neighborhood Hits	252	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL2_MOUSE
NC score	0.480293 (rank : 10)	θ value	5.40856e-29 (rank : 8)
Query Neighborhood Hits	252	Target Neighborhood Hits	240	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.479487 (rank : 11)	θ value	1.4233e-29 (rank : 5)
Query Neighborhood Hits	252	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_MOUSE
NC score	0.479229 (rank : 12)	θ value	7.80994e-28 (rank : 10)
Query Neighborhood Hits	252	Target Neighborhood Hits	237	Shared Neighborhood Hits	18
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

PCOC1_HUMAN
NC score	0.210689 (rank : 13)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	252	Target Neighborhood Hits	146	Shared Neighborhood Hits	18
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
NC score	0.209768 (rank : 14)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	252	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_MOUSE
NC score	0.207793 (rank : 15)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	252	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_HUMAN
NC score	0.206003 (rank : 16)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	252	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_MOUSE
NC score	0.192171 (rank : 17)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	252	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

NRP1_MOUSE
NC score	0.187352 (rank : 18)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	252	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.185627 (rank : 19)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	252	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NETO2_MOUSE
NC score	0.185238 (rank : 20)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	252	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_HUMAN
NC score	0.184580 (rank : 21)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	252	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO1_HUMAN
NC score	0.183728 (rank : 22)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	252	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
NC score	0.182777 (rank : 23)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	252	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

PDGFD_HUMAN
NC score	0.181676 (rank : 24)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	252	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

MFRP_HUMAN
NC score	0.178442 (rank : 25)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	252	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
NC score	0.174771 (rank : 26)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	252	Target Neighborhood Hits	166	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NRP2_HUMAN
NC score	0.173271 (rank : 27)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	252	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

SEZ6L_HUMAN
NC score	0.169410 (rank : 28)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	252	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

DMBT1_MOUSE
NC score	0.165454 (rank : 29)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	252	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

NRP2_MOUSE
NC score	0.164162 (rank : 30)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	252	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

TSG6_HUMAN
NC score	0.162260 (rank : 31)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	252	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

CUZD1_HUMAN
NC score	0.161075 (rank : 32)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	252	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

TSG6_MOUSE
NC score	0.160210 (rank : 33)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	252	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

CUZD1_MOUSE
NC score	0.155210 (rank : 34)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	252	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

CUBN_MOUSE
NC score	0.155184 (rank : 35)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	252	Target Neighborhood Hits	477	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUBN_HUMAN
NC score	0.154095 (rank : 36)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	252	Target Neighborhood Hits	482	Shared Neighborhood Hits	15
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CSMD2_HUMAN
NC score	0.152916 (rank : 37)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	252	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_HUMAN
NC score	0.149160 (rank : 38)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	252	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD3_HUMAN
NC score	0.148535 (rank : 39)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	252	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD1_MOUSE
NC score	0.147459 (rank : 40)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	252	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LRP12_MOUSE
NC score	0.142861 (rank : 41)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	252	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.142409 (rank : 42)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	252	Target Neighborhood Hits	205	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

DMBT1_HUMAN
NC score	0.134116 (rank : 43)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	252	Target Neighborhood Hits	152	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DCBD1_MOUSE
NC score	0.120031 (rank : 44)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	252	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
NC score	0.114582 (rank : 45)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	252	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

ATRN_HUMAN
NC score	0.110825 (rank : 46)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	252	Target Neighborhood Hits	525	Shared Neighborhood Hits	16
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

DCBD2_MOUSE
NC score	0.110344 (rank : 47)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	252	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

BSN_MOUSE
NC score	0.109726 (rank : 48)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	252	Target Neighborhood Hits	2057	Shared Neighborhood Hits	165
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MUC1_HUMAN
NC score	0.109541 (rank : 49)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	252	Target Neighborhood Hits	975	Shared Neighborhood Hits	141
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

LRP3_HUMAN
NC score	0.109055 (rank : 50)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	252	Target Neighborhood Hits	280	Shared Neighborhood Hits	32
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ATRN_MOUSE
NC score	0.108526 (rank : 51)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	252	Target Neighborhood Hits	519	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

C1R_HUMAN
NC score	0.106552 (rank : 52)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	252	Target Neighborhood Hits	364	Shared Neighborhood Hits	12
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CS016_HUMAN
NC score	0.104160 (rank : 53)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	252	Target Neighborhood Hits	310	Shared Neighborhood Hits	41
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

KREM2_HUMAN
NC score	0.104017 (rank : 54)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	252	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

C1RA_MOUSE
NC score	0.103709 (rank : 55)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	252	Target Neighborhood Hits	379	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

MASP1_HUMAN
NC score	0.103527 (rank : 56)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	252	Target Neighborhood Hits	369	Shared Neighborhood Hits	12
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

C1RB_MOUSE
NC score	0.102348 (rank : 57)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	252	Target Neighborhood Hits	380	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CS1A_MOUSE
NC score	0.102224 (rank : 58)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	252	Target Neighborhood Hits	360	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
NC score	0.101957 (rank : 59)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	252	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP1_MOUSE
NC score	0.101840 (rank : 60)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	252	Target Neighborhood Hits	364	Shared Neighborhood Hits	12
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

GP126_HUMAN
NC score	0.101139 (rank : 61)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	252	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

C1S_HUMAN
NC score	0.101078 (rank : 62)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	252	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP2_HUMAN
NC score	0.101073 (rank : 63)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	252	Target Neighborhood Hits	364	Shared Neighborhood Hits	12
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

DCBD1_HUMAN
NC score	0.100387 (rank : 64)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	252	Target Neighborhood Hits	110	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

MASP2_MOUSE
NC score	0.099978 (rank : 65)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	252	Target Neighborhood Hits	382	Shared Neighborhood Hits	12
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

KREM2_MOUSE
NC score	0.096971 (rank : 66)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	252	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

OGFR_HUMAN
NC score	0.096845 (rank : 67)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	252	Target Neighborhood Hits	1582	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MUC13_MOUSE
NC score	0.095406 (rank : 68)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	252	Target Neighborhood Hits	447	Shared Neighborhood Hits	42
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

BSN_HUMAN
NC score	0.095105 (rank : 69)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	252	Target Neighborhood Hits	1537	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PRRT3_HUMAN
NC score	0.091635 (rank : 70)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	252	Target Neighborhood Hits	998	Shared Neighborhood Hits	129
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

KREM1_HUMAN
NC score	0.090701 (rank : 71)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	252	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

PCLO_MOUSE
NC score	0.089436 (rank : 72)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	252	Target Neighborhood Hits	2275	Shared Neighborhood Hits	158
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NACAM_MOUSE
NC score	0.089343 (rank : 73)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	252	Target Neighborhood Hits	1866	Shared Neighborhood Hits	147
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

JPH2_HUMAN
NC score	0.088095 (rank : 74)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	252	Target Neighborhood Hits	639	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MAMC2_MOUSE
NC score	0.086269 (rank : 75)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	252	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

SYN1_HUMAN
NC score	0.084320 (rank : 76)	θ value	0.00869519 (rank : 17)
Query Neighborhood Hits	252	Target Neighborhood Hits	419	Shared Neighborhood Hits	60
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

EGFL7_HUMAN
NC score	0.083387 (rank : 77)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	252	Target Neighborhood Hits	325	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

CIC_HUMAN
NC score	0.083285 (rank : 78)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	252	Target Neighborhood Hits	992	Shared Neighborhood Hits	123
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BAT3_MOUSE
NC score	0.080682 (rank : 79)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	252	Target Neighborhood Hits	518	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

KREM1_MOUSE
NC score	0.079455 (rank : 80)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	252	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

K1802_MOUSE
NC score	0.078683 (rank : 81)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	252	Target Neighborhood Hits	1596	Shared Neighborhood Hits	126
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAMC2_HUMAN
NC score	0.078671 (rank : 82)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	252	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NFAC1_HUMAN
NC score	0.078555 (rank : 83)	θ value	0.00134147 (rank : 13)
Query Neighborhood Hits	252	Target Neighborhood Hits	312	Shared Neighborhood Hits	50
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SON_HUMAN
NC score	0.078321 (rank : 84)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	252	Target Neighborhood Hits	1568	Shared Neighborhood Hits	143
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SYN1_MOUSE
NC score	0.078090 (rank : 85)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	252	Target Neighborhood Hits	363	Shared Neighborhood Hits	52
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TAF4_HUMAN
NC score	0.077333 (rank : 86)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	252	Target Neighborhood Hits	687	Shared Neighborhood Hits	72
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

NCOA6_HUMAN
NC score	0.077217 (rank : 87)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	252	Target Neighborhood Hits	1202	Shared Neighborhood Hits	137
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PCLO_HUMAN
NC score	0.077206 (rank : 88)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	252	Target Neighborhood Hits	2046	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CD248_HUMAN
NC score	0.077002 (rank : 89)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	252	Target Neighborhood Hits	679	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

BAT2_HUMAN
NC score	0.076626 (rank : 90)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	252	Target Neighborhood Hits	931	Shared Neighborhood Hits	113
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MDC1_HUMAN
NC score	0.076518 (rank : 91)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	252	Target Neighborhood Hits	1446	Shared Neighborhood Hits	110
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ENTK_MOUSE
NC score	0.075507 (rank : 92)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	252	Target Neighborhood Hits	338	Shared Neighborhood Hits	12
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

MLL3_MOUSE
NC score	0.075120 (rank : 93)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	252	Target Neighborhood Hits	1399	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

DOT1L_HUMAN
NC score	0.075037 (rank : 94)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	252	Target Neighborhood Hits	660	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

MAGE1_HUMAN
NC score	0.074460 (rank : 95)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	252	Target Neighborhood Hits	1389	Shared Neighborhood Hits	161
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BAT3_HUMAN
NC score	0.074262 (rank : 96)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	252	Target Neighborhood Hits	490	Shared Neighborhood Hits	81
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CD248_MOUSE
NC score	0.073424 (rank : 97)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	252	Target Neighborhood Hits	578	Shared Neighborhood Hits	55
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

RGS3_MOUSE
NC score	0.072688 (rank : 98)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	252	Target Neighborhood Hits	1621	Shared Neighborhood Hits	160
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BCL9_HUMAN
NC score	0.072673 (rank : 99)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	252	Target Neighborhood Hits	1008	Shared Neighborhood Hits	127
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

GSCR1_HUMAN
NC score	0.072658 (rank : 100)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	252	Target Neighborhood Hits	674	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CIC_MOUSE
NC score	0.072195 (rank : 101)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	252	Target Neighborhood Hits	742	Shared Neighborhood Hits	92
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MAVS_HUMAN
NC score	0.072060 (rank : 102)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	252	Target Neighborhood Hits	271	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

IF35_MOUSE
NC score	0.071893 (rank : 103)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	252	Target Neighborhood Hits	210	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

BAT2_MOUSE
NC score	0.071578 (rank : 104)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	252	Target Neighborhood Hits	947	Shared Neighborhood Hits	111
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DIDO1_HUMAN
NC score	0.070890 (rank : 105)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	252	Target Neighborhood Hits	960	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

VASP_HUMAN
NC score	0.070626 (rank : 106)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	252	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

CS007_HUMAN
NC score	0.070403 (rank : 107)	θ value	0.00390308 (rank : 14)
Query Neighborhood Hits	252	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CN032_MOUSE
NC score	0.070023 (rank : 108)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	252	Target Neighborhood Hits	233	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CSF1_HUMAN
NC score	0.069946 (rank : 109)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	252	Target Neighborhood Hits	258	Shared Neighborhood Hits	53
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

GRIN1_HUMAN
NC score	0.069736 (rank : 110)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	252	Target Neighborhood Hits	681	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NFAC1_MOUSE
NC score	0.069513 (rank : 111)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	252	Target Neighborhood Hits	92	Shared Neighborhood Hits	19
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

MLL3_HUMAN
NC score	0.069346 (rank : 112)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	252	Target Neighborhood Hits	1644	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ELN_HUMAN
NC score	0.069145 (rank : 113)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	252	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

LTBP3_MOUSE
NC score	0.069029 (rank : 114)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	252	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

IRS2_MOUSE
NC score	0.068990 (rank : 115)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	252	Target Neighborhood Hits	248	Shared Neighborhood Hits	38
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

ENTK_HUMAN
NC score	0.068858 (rank : 116)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	252	Target Neighborhood Hits	310	Shared Neighborhood Hits	11
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

SSBP4_HUMAN
NC score	0.068687 (rank : 117)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	252	Target Neighborhood Hits	753	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

PROS_HUMAN
NC score	0.068170 (rank : 118)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	252	Target Neighborhood Hits	340	Shared Neighborhood Hits	17
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

MATN2_MOUSE
NC score	0.067839 (rank : 119)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	252	Target Neighborhood Hits	356	Shared Neighborhood Hits	15
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

SCUB3_MOUSE
NC score	0.067831 (rank : 120)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	252	Target Neighborhood Hits	442	Shared Neighborhood Hits	11
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PI5PA_HUMAN
NC score	0.067516 (rank : 121)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	252	Target Neighborhood Hits	749	Shared Neighborhood Hits	121
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MDC1_MOUSE
NC score	0.067342 (rank : 122)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	252	Target Neighborhood Hits	998	Shared Neighborhood Hits	99
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PHXR5_MOUSE
NC score	0.067147 (rank : 123)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	252	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

SCUB3_HUMAN
NC score	0.066928 (rank : 124)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	252	Target Neighborhood Hits	428	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

C1QR1_MOUSE
NC score	0.066405 (rank : 125)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	252	Target Neighborhood Hits	342	Shared Neighborhood Hits	15
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

MATN2_HUMAN
NC score	0.065097 (rank : 126)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	252	Target Neighborhood Hits	365	Shared Neighborhood Hits	16
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

SRRM2_MOUSE
NC score	0.064792 (rank : 127)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	252	Target Neighborhood Hits	1470	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CABIN_HUMAN
NC score	0.064005 (rank : 128)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	252	Target Neighborhood Hits	490	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

TRAF4_MOUSE
NC score	0.063384 (rank : 129)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	252	Target Neighborhood Hits	338	Shared Neighborhood Hits	6
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

ZN385_HUMAN
NC score	0.063195 (rank : 130)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	252	Target Neighborhood Hits	614	Shared Neighborhood Hits	107
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

LTBP2_MOUSE
NC score	0.063000 (rank : 131)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	252	Target Neighborhood Hits	617	Shared Neighborhood Hits	41
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CO2A1_HUMAN
NC score	0.062698 (rank : 132)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	252	Target Neighborhood Hits	486	Shared Neighborhood Hits	77
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

IRS2_HUMAN
NC score	0.062577 (rank : 133)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	252	Target Neighborhood Hits	262	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

ST14_HUMAN
NC score	0.062450 (rank : 134)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	252	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

NCOA6_MOUSE
NC score	0.062449 (rank : 135)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	252	Target Neighborhood Hits	1076	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ELN_MOUSE
NC score	0.062353 (rank : 136)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	252	Target Neighborhood Hits	105	Shared Neighborhood Hits	19
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

VASP_MOUSE
NC score	0.062244 (rank : 137)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	252	Target Neighborhood Hits	195	Shared Neighborhood Hits	30
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

SRRM1_MOUSE
NC score	0.062219 (rank : 138)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	252	Target Neighborhood Hits	966	Shared Neighborhood Hits	84
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PRP2_MOUSE
NC score	0.062205 (rank : 139)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	252	Target Neighborhood Hits	347	Shared Neighborhood Hits	50
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

FBN1_MOUSE
NC score	0.061890 (rank : 140)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	252	Target Neighborhood Hits	563	Shared Neighborhood Hits	18
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

SYNJ1_HUMAN
NC score	0.061778 (rank : 141)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	252	Target Neighborhood Hits	498	Shared Neighborhood Hits	63
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PROS_MOUSE
NC score	0.061699 (rank : 142)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	252	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FBLN5_HUMAN
NC score	0.061229 (rank : 143)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	252	Target Neighborhood Hits	329	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

MLL2_HUMAN
NC score	0.061189 (rank : 144)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	252	Target Neighborhood Hits	1788	Shared Neighborhood Hits	125
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BCL9_MOUSE
NC score	0.061064 (rank : 145)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	252	Target Neighborhood Hits	770	Shared Neighborhood Hits	106
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

ST14_MOUSE
NC score	0.060806 (rank : 146)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	252	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TAU_HUMAN
NC score	0.060671 (rank : 147)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	252	Target Neighborhood Hits	448	Shared Neighborhood Hits	68
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

MUCDL_HUMAN
NC score	0.060611 (rank : 148)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	252	Target Neighborhood Hits	777	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

TAU_MOUSE
NC score	0.060550 (rank : 149)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	252	Target Neighborhood Hits	502	Shared Neighborhood Hits	79
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

FBN1_HUMAN
NC score	0.059951 (rank : 150)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	252	Target Neighborhood Hits	557	Shared Neighborhood Hits	17
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

SYNJ1_MOUSE
NC score	0.059880 (rank : 151)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	252	Target Neighborhood Hits	516	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TRAF4_HUMAN
NC score	0.059766 (rank : 152)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	252	Target Neighborhood Hits	373	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

CO2A1_MOUSE
NC score	0.059008 (rank : 153)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	252	Target Neighborhood Hits	483	Shared Neighborhood Hits	70
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

FBLN5_MOUSE
NC score	0.058994 (rank : 154)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	252	Target Neighborhood Hits	317	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

CLC14_HUMAN
NC score	0.058895 (rank : 155)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	252	Target Neighborhood Hits	143	Shared Neighborhood Hits	14
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

MATN1_MOUSE
NC score	0.058415 (rank : 156)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	252	Target Neighborhood Hits	186	Shared Neighborhood Hits	13
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

FBN3_HUMAN
NC score	0.058352 (rank : 157)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	252	Target Neighborhood Hits	543	Shared Neighborhood Hits	18
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MATN4_HUMAN
NC score	0.057706 (rank : 158)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	252	Target Neighborhood Hits	287	Shared Neighborhood Hits	13
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

NFH_MOUSE
NC score	0.057412 (rank : 159)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	252	Target Neighborhood Hits	2247	Shared Neighborhood Hits	148
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MISS_MOUSE
NC score	0.057292 (rank : 160)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	252	Target Neighborhood Hits	444	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

LEG3_HUMAN
NC score	0.057154 (rank : 161)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	252	Target Neighborhood Hits	124	Shared Neighborhood Hits	21
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

CO5A2_HUMAN
NC score	0.057144 (rank : 162)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	252	Target Neighborhood Hits	760	Shared Neighborhood Hits	103
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

FBN2_HUMAN
NC score	0.057023 (rank : 163)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	252	Target Neighborhood Hits	560	Shared Neighborhood Hits	21
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

CLC14_MOUSE
NC score	0.056721 (rank : 164)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	252	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

MATN1_HUMAN
NC score	0.056704 (rank : 165)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	252	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

ENAH_MOUSE
NC score	0.056653 (rank : 166)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	252	Target Neighborhood Hits	919	Shared Neighborhood Hits	59
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SC24C_HUMAN
NC score	0.056542 (rank : 167)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	252	Target Neighborhood Hits	662	Shared Neighborhood Hits	109
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MEGF6_HUMAN
NC score	0.056460 (rank : 168)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	252	Target Neighborhood Hits	671	Shared Neighborhood Hits	19
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CSPG5_HUMAN
NC score	0.056298 (rank : 169)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	252	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

JPH2_MOUSE
NC score	0.056287 (rank : 170)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	252	Target Neighborhood Hits	279	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SSFA2_MOUSE
NC score	0.056242 (rank : 171)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	252	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q922B9, Q8VEF7	Gene names	Ssfa2
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2.

FBN2_MOUSE
NC score	0.056077 (rank : 172)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	252	Target Neighborhood Hits	549	Shared Neighborhood Hits	19
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LTB1L_MOUSE
NC score	0.055921 (rank : 173)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	252	Target Neighborhood Hits	514	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

EGFL8_MOUSE
NC score	0.055920 (rank : 174)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	252	Target Neighborhood Hits	266	Shared Neighborhood Hits	12
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

CEL_HUMAN
NC score	0.055713 (rank : 175)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	252	Target Neighborhood Hits	896	Shared Neighborhood Hits	117
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

LTB1S_MOUSE
NC score	0.055649 (rank : 176)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	252	Target Neighborhood Hits	479	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

T22D4_HUMAN
NC score	0.055484 (rank : 177)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	252	Target Neighborhood Hits	403	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

ATX2_MOUSE
NC score	0.055396 (rank : 178)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	252	Target Neighborhood Hits	445	Shared Neighborhood Hits	54
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

SRRM1_HUMAN
NC score	0.055221 (rank : 179)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	252	Target Neighborhood Hits	690	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

LTBP3_HUMAN
NC score	0.055120 (rank : 180)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	252	Target Neighborhood Hits	502	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

EGFL7_MOUSE
NC score	0.054966 (rank : 181)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	252	Target Neighborhood Hits	287	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

SELPL_MOUSE
NC score	0.054886 (rank : 182)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	252	Target Neighborhood Hits	588	Shared Neighborhood Hits	73
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CRSP2_HUMAN
NC score	0.054619 (rank : 183)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	252	Target Neighborhood Hits	380	Shared Neighborhood Hits	59
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CSPG5_MOUSE
NC score	0.054455 (rank : 184)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	252	Target Neighborhood Hits	211	Shared Neighborhood Hits	33
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

UROL1_MOUSE
NC score	0.054207 (rank : 185)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	252	Target Neighborhood Hits	235	Shared Neighborhood Hits	18
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

GGN_MOUSE
NC score	0.054095 (rank : 186)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	252	Target Neighborhood Hits	311	Shared Neighborhood Hits	40
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CO9A1_MOUSE
NC score	0.053878 (rank : 187)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	252	Target Neighborhood Hits	477	Shared Neighborhood Hits	81
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

EGF_MOUSE
NC score	0.053837 (rank : 188)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	252	Target Neighborhood Hits	358	Shared Neighborhood Hits	15
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

CO3A1_MOUSE
NC score	0.053661 (rank : 189)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	252	Target Neighborhood Hits	466	Shared Neighborhood Hits	56
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MBD5_HUMAN
NC score	0.053449 (rank : 190)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	252	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

LTB1L_HUMAN
NC score	0.053209 (rank : 191)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	252	Target Neighborhood Hits	553	Shared Neighborhood Hits	37
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MDGA1_HUMAN
NC score	0.052991 (rank : 192)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	252	Target Neighborhood Hits	358	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

CO3A1_HUMAN
NC score	0.052970 (rank : 193)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	252	Target Neighborhood Hits	452	Shared Neighborhood Hits	54
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

PSL1_HUMAN
NC score	0.052775 (rank : 194)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	252	Target Neighborhood Hits	650	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

LTB1S_HUMAN
NC score	0.052697 (rank : 195)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	252	Target Neighborhood Hits	502	Shared Neighborhood Hits	31
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SON_MOUSE
NC score	0.052531 (rank : 196)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	252	Target Neighborhood Hits	957	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

EGFL8_HUMAN
NC score	0.052416 (rank : 197)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	252	Target Neighborhood Hits	270	Shared Neighborhood Hits	12
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

OGFR_MOUSE
NC score	0.052336 (rank : 198)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	252	Target Neighborhood Hits	584	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

FBLN3_MOUSE
NC score	0.052169 (rank : 199)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	252	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

TGON2_HUMAN
NC score	0.051921 (rank : 200)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	252	Target Neighborhood Hits	1037	Shared Neighborhood Hits	82
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RGS3_HUMAN
NC score	0.051890 (rank : 201)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	252	Target Neighborhood Hits	1375	Shared Neighborhood Hits	134
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

LTBP2_HUMAN
NC score	0.051741 (rank : 202)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	252	Target Neighborhood Hits	552	Shared Neighborhood Hits	28
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MATN4_MOUSE
NC score	0.051638 (rank : 203)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	252	Target Neighborhood Hits	277	Shared Neighborhood Hits	13
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MBD6_HUMAN
NC score	0.051331 (rank : 204)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	252	Target Neighborhood Hits	349	Shared Neighborhood Hits	40
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PROZ_MOUSE
NC score	0.051298 (rank : 205)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	252	Target Neighborhood Hits	410	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FBLN2_HUMAN
NC score	0.051231 (rank : 206)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	252	Target Neighborhood Hits	392	Shared Neighborhood Hits	21
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

SRRM2_HUMAN
NC score	0.051095 (rank : 207)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	252	Target Neighborhood Hits	1296	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

FBLN2_MOUSE
NC score	0.051074 (rank : 208)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	252	Target Neighborhood Hits	505	Shared Neighborhood Hits	35
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

GAS6_HUMAN
NC score	0.051024 (rank : 209)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	252	Target Neighborhood Hits	348	Shared Neighborhood Hits	14
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

SNPC4_HUMAN
NC score	0.050915 (rank : 210)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	252	Target Neighborhood Hits	589	Shared Neighborhood Hits	97
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CO1A1_MOUSE
NC score	0.050576 (rank : 211)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	252	Target Neighborhood Hits	457	Shared Neighborhood Hits	60
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO9A1_HUMAN
NC score	0.048927 (rank : 212)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	252	Target Neighborhood Hits	420	Shared Neighborhood Hits	62
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

K1802_HUMAN
NC score	0.048435 (rank : 213)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	252	Target Neighborhood Hits	1378	Shared Neighborhood Hits	99
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SSFA2_HUMAN
NC score	0.047661 (rank : 214)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	252	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	P28290, Q96E36	Gene names	SSFA2, CS1
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2 (Cleavage signal-1 protein) (CS-1).

CSKI2_HUMAN
NC score	0.046847 (rank : 215)	θ value	0.00509761 (rank : 15)
Query Neighborhood Hits	252	Target Neighborhood Hits	747	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CO1A2_HUMAN
NC score	0.046691 (rank : 216)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	252	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

RERE_MOUSE
NC score	0.046602 (rank : 217)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	252	Target Neighborhood Hits	785	Shared Neighborhood Hits	64
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

PRG4_HUMAN
NC score	0.046448 (rank : 218)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	252	Target Neighborhood Hits	764	Shared Neighborhood Hits	58
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

NOTC2_HUMAN
NC score	0.045466 (rank : 219)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	252	Target Neighborhood Hits	1113	Shared Neighborhood Hits	77
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CPSF6_HUMAN
NC score	0.045266 (rank : 220)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	252	Target Neighborhood Hits	359	Shared Neighborhood Hits	47
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
NC score	0.045240 (rank : 221)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	252	Target Neighborhood Hits	356	Shared Neighborhood Hits	47
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CSKI2_MOUSE
NC score	0.044885 (rank : 222)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	252	Target Neighborhood Hits	812	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

BASP_MOUSE
NC score	0.044599 (rank : 223)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	252	Target Neighborhood Hits	260	Shared Neighborhood Hits	28
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

ARID2_HUMAN
NC score	0.044227 (rank : 224)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	252	Target Neighborhood Hits	302	Shared Neighborhood Hits	28
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

CO4A1_MOUSE
NC score	0.044221 (rank : 225)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	252	Target Neighborhood Hits	450	Shared Neighborhood Hits	70
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

FXL19_MOUSE
NC score	0.044212 (rank : 226)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	252	Target Neighborhood Hits	217	Shared Neighborhood Hits	33
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

ARI1B_HUMAN
NC score	0.043794 (rank : 227)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	252	Target Neighborhood Hits	567	Shared Neighborhood Hits	75
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

COGA1_HUMAN
NC score	0.043536 (rank : 228)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	252	Target Neighborhood Hits	345	Shared Neighborhood Hits	45
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

NOTC2_MOUSE
NC score	0.042827 (rank : 229)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	252	Target Neighborhood Hits	1069	Shared Neighborhood Hits	58
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CSKI1_HUMAN
NC score	0.041244 (rank : 230)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	252	Target Neighborhood Hits	997	Shared Neighborhood Hits	95
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NOTC3_MOUSE
NC score	0.040857 (rank : 231)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	252	Target Neighborhood Hits	975	Shared Neighborhood Hits	45
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.040424 (rank : 232)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	252	Target Neighborhood Hits	906	Shared Neighborhood Hits	31
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

RERE_HUMAN
NC score	0.040352 (rank : 233)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	252	Target Neighborhood Hits	779	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

TCOF_MOUSE
NC score	0.040268 (rank : 234)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	252	Target Neighborhood Hits	471	Shared Neighborhood Hits	41
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

PYGO2_HUMAN
NC score	0.040046 (rank : 235)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	252	Target Neighborhood Hits	189	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RTN4_MOUSE
NC score	0.039304 (rank : 236)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	252	Target Neighborhood Hits	341	Shared Neighborhood Hits	29
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

WASP_MOUSE
NC score	0.039053 (rank : 237)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	252	Target Neighborhood Hits	223	Shared Neighborhood Hits	32
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

UBE4B_HUMAN
NC score	0.039000 (rank : 238)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	252	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

PO121_MOUSE
NC score	0.038963 (rank : 239)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	252	Target Neighborhood Hits	345	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

JPH1_HUMAN
NC score	0.038847 (rank : 240)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	252	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HDC5	Gene names	JPH1, JP1
Domain Architecture	No domain graphic available
Description	Junctophilin-1 (Junctophilin type 1) (JP-1).

CO4A6_HUMAN
NC score	0.038745 (rank : 241)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	252	Target Neighborhood Hits	318	Shared Neighborhood Hits	42
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

ICAL_MOUSE
NC score	0.038257 (rank : 242)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	252	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

SHAN1_HUMAN
NC score	0.038157 (rank : 243)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	252	Target Neighborhood Hits	1041	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TCOF_HUMAN
NC score	0.037942 (rank : 244)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	252	Target Neighborhood Hits	543	Shared Neighborhood Hits	48
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CO7A1_HUMAN
NC score	0.037934 (rank : 245)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	252	Target Neighborhood Hits	807	Shared Neighborhood Hits	86
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

SET1A_HUMAN
NC score	0.037757 (rank : 246)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	252	Target Neighborhood Hits	690	Shared Neighborhood Hits	58
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

FXL19_HUMAN
NC score	0.037547 (rank : 247)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	252	Target Neighborhood Hits	147	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

SELO_HUMAN
NC score	0.037399 (rank : 248)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	252	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVL4, Q8WUI0	Gene names	SELO
Domain Architecture
Description	Selenoprotein O.

ZIM10_MOUSE
NC score	0.036921 (rank : 249)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	252	Target Neighborhood Hits	430	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

WASL_MOUSE
NC score	0.036810 (rank : 250)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	252	Target Neighborhood Hits	339	Shared Neighborhood Hits	37
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

PABP2_MOUSE
NC score	0.036717 (rank : 251)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	252	Target Neighborhood Hits	214	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PABP2_HUMAN
NC score	0.036171 (rank : 252)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	252	Target Neighborhood Hits	212	Shared Neighborhood Hits	12
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

MAML2_HUMAN
NC score	0.035671 (rank : 253)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	252	Target Neighborhood Hits	360	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

C1QRF_MOUSE
NC score	0.035440 (rank : 254)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	252	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	O88992	Gene names	C1ql1, C1qrf, Crf
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

SRBP1_MOUSE
NC score	0.035412 (rank : 255)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	252	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

CO8A1_HUMAN
NC score	0.035200 (rank : 256)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	252	Target Neighborhood Hits	288	Shared Neighborhood Hits	35
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

EPN1_MOUSE
NC score	0.034878 (rank : 257)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	252	Target Neighborhood Hits	240	Shared Neighborhood Hits	36
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

COAA1_HUMAN
NC score	0.034665 (rank : 258)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	252	Target Neighborhood Hits	316	Shared Neighborhood Hits	38
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

ENAH_HUMAN
NC score	0.034633 (rank : 259)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	252	Target Neighborhood Hits	784	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

C1QRF_HUMAN
NC score	0.034165 (rank : 260)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	252	Target Neighborhood Hits	143	Shared Neighborhood Hits	22
SwissProt Accessions	O75973	Gene names	C1QL1, C1QRF, CRF
Domain Architecture
Description	C1q-related factor precursor (Complement component 1 Q subcomponent- like 1).

EPN1_HUMAN
NC score	0.033856 (rank : 261)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	252	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

BAD_HUMAN
NC score	0.033392 (rank : 262)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	252	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q92934, O14803	Gene names	BAD, BBC6, BCL2L8
Domain Architecture	No domain graphic available
Description	Bcl2 antagonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl- XL/Bcl-2-associated death promoter) (Bcl-2-like 8 protein).

ARMX2_HUMAN
NC score	0.033169 (rank : 263)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	252	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

RP3A_MOUSE
NC score	0.032667 (rank : 264)	θ value	1.06291 (rank : 84)
Query Neighborhood Hits	252	Target Neighborhood Hits	510	Shared Neighborhood Hits	69
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SFPQ_HUMAN
NC score	0.031645 (rank : 265)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	252	Target Neighborhood Hits	986	Shared Neighborhood Hits	71
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

DEN1A_HUMAN
NC score	0.030878 (rank : 266)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	252	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

GA2L1_HUMAN
NC score	0.029684 (rank : 267)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	252	Target Neighborhood Hits	177	Shared Neighborhood Hits	32
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

FMN2_HUMAN
NC score	0.028828 (rank : 268)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	252	Target Neighborhood Hits	484	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

SRBP1_HUMAN
NC score	0.028753 (rank : 269)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	252	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

RBM12_MOUSE
NC score	0.028603 (rank : 270)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	252	Target Neighborhood Hits	313	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RPTOR_HUMAN
NC score	0.028379 (rank : 271)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	252	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

CCNK_MOUSE
NC score	0.027915 (rank : 272)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	252	Target Neighborhood Hits	350	Shared Neighborhood Hits	32
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

RIMB1_HUMAN
NC score	0.027089 (rank : 273)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	252	Target Neighborhood Hits	1479	Shared Neighborhood Hits	86
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SFR15_HUMAN
NC score	0.026639 (rank : 274)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	252	Target Neighborhood Hits	368	Shared Neighborhood Hits	28
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

TENS1_HUMAN
NC score	0.026595 (rank : 275)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	252	Target Neighborhood Hits	400	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

PHC2_MOUSE
NC score	0.025992 (rank : 276)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	252	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

DYN1_HUMAN
NC score	0.025664 (rank : 277)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	252	Target Neighborhood Hits	216	Shared Neighborhood Hits	41
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

HCN2_HUMAN
NC score	0.025497 (rank : 278)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	252	Target Neighborhood Hits	369	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

SI1L3_HUMAN
NC score	0.025120 (rank : 279)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	252	Target Neighborhood Hits	305	Shared Neighborhood Hits	42
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SEN34_MOUSE
NC score	0.024572 (rank : 280)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	252	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

DYN1_MOUSE
NC score	0.024444 (rank : 281)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	252	Target Neighborhood Hits	168	Shared Neighborhood Hits	31
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

RUNX3_MOUSE
NC score	0.024420 (rank : 282)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	252	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

ADRM1_MOUSE
NC score	0.024227 (rank : 283)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	252	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

CAC1B_MOUSE
NC score	0.023661 (rank : 284)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	252	Target Neighborhood Hits	351	Shared Neighborhood Hits	40
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

ZDHC1_MOUSE
NC score	0.023630 (rank : 285)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	252	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0N9, Q8BJ24	Gene names	Zdhhc1
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1).

FOG1_MOUSE
NC score	0.023439 (rank : 286)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	252	Target Neighborhood Hits	1237	Shared Neighborhood Hits	99
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

RPTOR_MOUSE
NC score	0.023432 (rank : 287)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	252	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SFR16_HUMAN
NC score	0.023383 (rank : 288)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	252	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N2M8, O96026, Q6UW71, Q96DX2	Gene names	SFRS16, SWAP2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2).

WBS14_MOUSE
NC score	0.023383 (rank : 289)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	252	Target Neighborhood Hits	171	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

EP400_MOUSE
NC score	0.022517 (rank : 290)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	252	Target Neighborhood Hits	592	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

SMRC2_MOUSE
NC score	0.022347 (rank : 291)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	252	Target Neighborhood Hits	487	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TNC6B_HUMAN
NC score	0.022292 (rank : 292)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	252	Target Neighborhood Hits	256	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

TLE1_MOUSE
NC score	0.022126 (rank : 293)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	252	Target Neighborhood Hits	491	Shared Neighborhood Hits	59
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

MKL2_HUMAN
NC score	0.021708 (rank : 294)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	252	Target Neighborhood Hits	274	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

WNK2_HUMAN
NC score	0.021658 (rank : 295)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	252	Target Neighborhood Hits	1407	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CAC1H_MOUSE
NC score	0.021563 (rank : 296)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	252	Target Neighborhood Hits	230	Shared Neighborhood Hits	29
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

RECQ4_HUMAN
NC score	0.020996 (rank : 297)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	252	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

PHC3_MOUSE
NC score	0.020948 (rank : 298)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	252	Target Neighborhood Hits	194	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

TMM28_HUMAN
NC score	0.019906 (rank : 299)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	252	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	O75949	Gene names	TMEM28, TED
Domain Architecture	No domain graphic available
Description	Transmembrane protein 28 (TED protein).

RABX5_HUMAN
NC score	0.019627 (rank : 300)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	252	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

ANR43_HUMAN
NC score	0.019506 (rank : 301)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	252	Target Neighborhood Hits	209	Shared Neighborhood Hits	12
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

TLE1_HUMAN
NC score	0.019382 (rank : 302)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	252	Target Neighborhood Hits	485	Shared Neighborhood Hits	50
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

CAC1B_HUMAN
NC score	0.019350 (rank : 303)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	252	Target Neighborhood Hits	257	Shared Neighborhood Hits	22
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

HCFC1_MOUSE
NC score	0.019124 (rank : 304)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	252	Target Neighborhood Hits	348	Shared Neighborhood Hits	30
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

SSH1_MOUSE
NC score	0.018970 (rank : 305)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	252	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

LBXCO_HUMAN
NC score	0.018681 (rank : 306)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	252	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

PGCA_MOUSE
NC score	0.018513 (rank : 307)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	252	Target Neighborhood Hits	643	Shared Neighborhood Hits	41
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PHX2B_HUMAN
NC score	0.016715 (rank : 308)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	252	Target Neighborhood Hits	407	Shared Neighborhood Hits	25
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
NC score	0.016715 (rank : 309)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	252	Target Neighborhood Hits	407	Shared Neighborhood Hits	25
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

TTBK1_HUMAN
NC score	0.016446 (rank : 310)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	252	Target Neighborhood Hits	1058	Shared Neighborhood Hits	59
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TNKS1_HUMAN
NC score	0.015603 (rank : 311)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	252	Target Neighborhood Hits	477	Shared Neighborhood Hits	31
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TBX2_HUMAN
NC score	0.015487 (rank : 312)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	252	Target Neighborhood Hits	195	Shared Neighborhood Hits	28
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

ATF6B_MOUSE
NC score	0.015297 (rank : 313)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	252	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

DIAP1_MOUSE
NC score	0.015065 (rank : 314)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	252	Target Neighborhood Hits	839	Shared Neighborhood Hits	37
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

HES6_HUMAN
NC score	0.014655 (rank : 315)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	252	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

WNK4_HUMAN
NC score	0.014597 (rank : 316)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	252	Target Neighborhood Hits	1043	Shared Neighborhood Hits	48
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

RAD17_MOUSE
NC score	0.014458 (rank : 317)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	252	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NXW6, O88934, O89024	Gene names	Rad17
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17.

ADA19_HUMAN
NC score	0.014225 (rank : 318)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	252	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

AIM1_HUMAN
NC score	0.014223 (rank : 319)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	252	Target Neighborhood Hits	247	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

TIF1B_HUMAN
NC score	0.013973 (rank : 320)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	252	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

MAST1_HUMAN
NC score	0.013750 (rank : 321)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	252	Target Neighborhood Hits	1146	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

HUWE1_MOUSE
NC score	0.013675 (rank : 322)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	252	Target Neighborhood Hits	406	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

SPEG_HUMAN
NC score	0.013394 (rank : 323)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	252	Target Neighborhood Hits	1762	Shared Neighborhood Hits	103
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

IRX2_HUMAN
NC score	0.013376 (rank : 324)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	252	Target Neighborhood Hits	358	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

AAK1_HUMAN
NC score	0.012925 (rank : 325)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	252	Target Neighborhood Hits	1077	Shared Neighborhood Hits	64
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ANXA7_HUMAN
NC score	0.012832 (rank : 326)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	252	Target Neighborhood Hits	168	Shared Neighborhood Hits	20
SwissProt Accessions	P20073	Gene names	ANXA7, ANX7, SNX
Domain Architecture
Description	Annexin A7 (Annexin VII) (Synexin).

CNKR1_HUMAN
NC score	0.012744 (rank : 327)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	252	Target Neighborhood Hits	154	Shared Neighborhood Hits	13
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CUTL1_HUMAN
NC score	0.012634 (rank : 328)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	252	Target Neighborhood Hits	1574	Shared Neighborhood Hits	49
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

MAST1_MOUSE
NC score	0.012582 (rank : 329)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	252	Target Neighborhood Hits	1123	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

GATA4_HUMAN
NC score	0.012468 (rank : 330)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	252	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P43694	Gene names	GATA4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

SOX15_HUMAN
NC score	0.012464 (rank : 331)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	252	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

ANR50_HUMAN
NC score	0.012426 (rank : 332)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	252	Target Neighborhood Hits	361	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

NKX12_MOUSE
NC score	0.011545 (rank : 333)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	252	Target Neighborhood Hits	332	Shared Neighborhood Hits	10
SwissProt Accessions	P42580, Q9JHF2, Q9JKW5, Q9JKW6, Q9JKW9, Q9JKX0, Q9JKX1	Gene names	Nkx1-2, Nkx1.1, Sax1
Domain Architecture
Description	NK1 transcription factor-related protein 2 (Homeobox protein SAX-1) (NKX-1.1).

MBRL_MOUSE
NC score	0.011411 (rank : 334)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	252	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIV2, Q68EE1, Q6KAN7, Q7TS84, Q8CIV1, Q99K29	Gene names	ORF61
Domain Architecture	No domain graphic available
Description	Membralin.

FOXQ1_HUMAN
NC score	0.011093 (rank : 335)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	252	Target Neighborhood Hits	115	Shared Neighborhood Hits	12
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

M3K12_MOUSE
NC score	0.011080 (rank : 336)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	252	Target Neighborhood Hits	957	Shared Neighborhood Hits	37
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

PP4R1_MOUSE
NC score	0.010978 (rank : 337)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	252	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

SMRD3_HUMAN
NC score	0.010898 (rank : 338)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	252	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q6STE5, Q75MJ2, Q75MR8, Q92926, Q9BUH1	Gene names	SMARCD3, BAF60C
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C).

GCNL2_HUMAN
NC score	0.010894 (rank : 339)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	252	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

ZEP1_MOUSE
NC score	0.010657 (rank : 340)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	252	Target Neighborhood Hits	1063	Shared Neighborhood Hits	55
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

M3K12_HUMAN
NC score	0.010435 (rank : 341)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	252	Target Neighborhood Hits	940	Shared Neighborhood Hits	31
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

TMPSD_HUMAN
NC score	0.010266 (rank : 342)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	252	Target Neighborhood Hits	333	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

COE4_HUMAN
NC score	0.010262 (rank : 343)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	252	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQW3, Q5JY53, Q9NUB6, Q9P2A6	Gene names	EBF4, COE4, KIAA1442
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

MK07_HUMAN
NC score	0.009921 (rank : 344)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	252	Target Neighborhood Hits	1087	Shared Neighborhood Hits	52
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

IRAK1_MOUSE
NC score	0.009388 (rank : 345)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	252	Target Neighborhood Hits	784	Shared Neighborhood Hits	24
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

FOXF2_HUMAN
NC score	0.009020 (rank : 346)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	252	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

HNRPL_HUMAN
NC score	0.008829 (rank : 347)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	252	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P14866, Q9H3P3	Gene names	HNRPL
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein L (hnRNP L).

LIPA3_MOUSE
NC score	0.008742 (rank : 348)	θ value	6.88961 (rank : 214)
Query Neighborhood Hits	252	Target Neighborhood Hits	636	Shared Neighborhood Hits	15
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

HXD3_HUMAN
NC score	0.008690 (rank : 349)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	252	Target Neighborhood Hits	433	Shared Neighborhood Hits	27
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

SALL3_HUMAN
NC score	0.008666 (rank : 350)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	252	Target Neighborhood Hits	1066	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

M3K10_HUMAN
NC score	0.007907 (rank : 351)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	252	Target Neighborhood Hits	1071	Shared Neighborhood Hits	25
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

LPIN3_MOUSE
NC score	0.007876 (rank : 352)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	252	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

M3K4_MOUSE
NC score	0.007712 (rank : 353)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	252	Target Neighborhood Hits	924	Shared Neighborhood Hits	29
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

OSBP2_HUMAN
NC score	0.007538 (rank : 354)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	252	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

ARAF_HUMAN
NC score	0.007463 (rank : 355)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	252	Target Neighborhood Hits	924	Shared Neighborhood Hits	32
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

BRSK1_HUMAN
NC score	0.007451 (rank : 356)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	252	Target Neighborhood Hits	942	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

LIPA3_HUMAN
NC score	0.007281 (rank : 357)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	252	Target Neighborhood Hits	828	Shared Neighborhood Hits	17
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LYOX_MOUSE
NC score	0.007200 (rank : 358)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	252	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P28301	Gene names	Lox, Rrg
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase) (RAS excision protein).

ABL1_MOUSE
NC score	0.007192 (rank : 359)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	252	Target Neighborhood Hits	1178	Shared Neighborhood Hits	45
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ARX_HUMAN
NC score	0.007160 (rank : 360)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	252	Target Neighborhood Hits	401	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

FOXD2_HUMAN
NC score	0.007155 (rank : 361)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	252	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

HXD3_MOUSE
NC score	0.007141 (rank : 362)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	252	Target Neighborhood Hits	435	Shared Neighborhood Hits	19
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

CSTF2_MOUSE
NC score	0.007090 (rank : 363)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	252	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

HXA2_HUMAN
NC score	0.006334 (rank : 364)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	252	Target Neighborhood Hits	370	Shared Neighborhood Hits	21
SwissProt Accessions	O43364	Gene names	HOXA2
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-A2.

CD2L5_MOUSE
NC score	0.006084 (rank : 365)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	252	Target Neighborhood Hits	1011	Shared Neighborhood Hits	31
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

B4GT1_MOUSE
NC score	0.005914 (rank : 366)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	252	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

PLK3_HUMAN
NC score	0.005854 (rank : 367)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	252	Target Neighborhood Hits	865	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H4B4, Q15767, Q96CV1	Gene names	PLK3, CNK, FNK, PRK
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase) (Proliferation-related kinase).

DDX24_HUMAN
NC score	0.005390 (rank : 368)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	252	Target Neighborhood Hits	190	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

AZI1_MOUSE
NC score	0.005312 (rank : 369)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	252	Target Neighborhood Hits	990	Shared Neighborhood Hits	23
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BHLH8_HUMAN
NC score	0.005137 (rank : 370)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	252	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

SN_MOUSE
NC score	0.004784 (rank : 371)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	252	Target Neighborhood Hits	416	Shared Neighborhood Hits	5
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

ZN516_HUMAN
NC score	0.004540 (rank : 372)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	252	Target Neighborhood Hits	854	Shared Neighborhood Hits	41
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

LAP4_MOUSE
NC score	0.004534 (rank : 373)	θ value	6.88961 (rank : 213)
Query Neighborhood Hits	252	Target Neighborhood Hits	590	Shared Neighborhood Hits	21
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

BAI1_MOUSE
NC score	0.004149 (rank : 374)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	252	Target Neighborhood Hits	340	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

IGF1R_MOUSE
NC score	0.004004 (rank : 375)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	252	Target Neighborhood Hits	973	Shared Neighborhood Hits	23
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LAP2_MOUSE
NC score	0.003896 (rank : 376)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	252	Target Neighborhood Hits	482	Shared Neighborhood Hits	14
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

KLF15_HUMAN
NC score	0.003836 (rank : 377)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	252	Target Neighborhood Hits	720	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UIH9	Gene names	KLF15, KKLF
Domain Architecture
Description	Krueppel-like factor 15 (Kidney-enriched krueppel-like factor).

ANDR_HUMAN
NC score	0.002638 (rank : 378)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	252	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

KLF15_MOUSE
NC score	0.002059 (rank : 379)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	252	Target Neighborhood Hits	707	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EPW2, Q3UQB0	Gene names	Klf15, Cklf
Domain Architecture
Description	Krueppel-like factor 15 (Cardiovascular Krueppel-like factor).

BC11B_HUMAN
NC score	-0.000272 (rank : 380)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	252	Target Neighborhood Hits	761	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0K0, Q9H162	Gene names	BCL11B, CTIP2, RIT1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (hRit1) (COUP-TF-interacting protein 2).

ZN341_HUMAN
NC score	-0.000794 (rank : 381)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	252	Target Neighborhood Hits	803	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYN7, Q5JXM8, Q96ST5	Gene names	ZNF341
Domain Architecture	No domain graphic available
Description	Zinc finger protein 341.

ZN408_HUMAN
NC score	-0.001704 (rank : 382)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	252	Target Neighborhood Hits	775	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

ADA2A_MOUSE
NC score	-0.002924 (rank : 383)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	252	Target Neighborhood Hits	900	Shared Neighborhood Hits	11
SwissProt Accessions	Q01338	Gene names	Adra2a
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR).

ADA2B_MOUSE
NC score	-0.004328 (rank : 384)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	252	Target Neighborhood Hits	891	Shared Neighborhood Hits	3
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).