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Network neighborhood for query Sequence : TMPSD_HUMAN

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TMPSD_HUMAN
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TMPSD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	333	Target Neighborhood Hits	333	Shared Neighborhood Hits	333
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	0 (rank : 2)	NC score	0.995338 (rank : 2)
Query Neighborhood Hits	333	Target Neighborhood Hits	334	Shared Neighborhood Hits	241
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPS2_MOUSE
θ value	2.64714e-76 (rank : 3)	NC score	0.985812 (rank : 11)
Query Neighborhood Hits	333	Target Neighborhood Hits	243	Shared Neighborhood Hits	192
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_MOUSE
θ value	4.99229e-75 (rank : 4)	NC score	0.986545 (rank : 7)
Query Neighborhood Hits	333	Target Neighborhood Hits	239	Shared Neighborhood Hits	199
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS2_HUMAN
θ value	9.41505e-74 (rank : 5)	NC score	0.986430 (rank : 8)
Query Neighborhood Hits	333	Target Neighborhood Hits	252	Shared Neighborhood Hits	192
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	1.35953e-72 (rank : 6)	NC score	0.985769 (rank : 12)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	200
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS4_HUMAN
θ value	2.3998e-69 (rank : 7)	NC score	0.987496 (rank : 4)
Query Neighborhood Hits	333	Target Neighborhood Hits	203	Shared Neighborhood Hits	186
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS5_MOUSE
θ value	8.53533e-67 (rank : 8)	NC score	0.987392 (rank : 5)
Query Neighborhood Hits	333	Target Neighborhood Hits	185	Shared Neighborhood Hits	179
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS4_MOUSE
θ value	2.4834e-66 (rank : 9)	NC score	0.987597 (rank : 3)
Query Neighborhood Hits	333	Target Neighborhood Hits	210	Shared Neighborhood Hits	189
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	1.50663e-63 (rank : 10)	NC score	0.987112 (rank : 6)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	178
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

HEPS_HUMAN
θ value	9.1404e-61 (rank : 11)	NC score	0.986084 (rank : 9)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	2.65945e-60 (rank : 12)	NC score	0.985937 (rank : 10)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	176
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

KLKB1_HUMAN
θ value	6.77864e-56 (rank : 13)	NC score	0.980081 (rank : 32)
Query Neighborhood Hits	333	Target Neighborhood Hits	183	Shared Neighborhood Hits	174
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

TMPS6_MOUSE
θ value	1.97229e-55 (rank : 14)	NC score	0.952500 (rank : 75)
Query Neighborhood Hits	333	Target Neighborhood Hits	341	Shared Neighborhood Hits	190
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_MOUSE
θ value	1.97229e-55 (rank : 15)	NC score	0.947710 (rank : 84)
Query Neighborhood Hits	333	Target Neighborhood Hits	275	Shared Neighborhood Hits	189
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

KLKB1_MOUSE
θ value	2.57589e-55 (rank : 16)	NC score	0.980187 (rank : 31)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

ENTK_HUMAN
θ value	5.73848e-55 (rank : 17)	NC score	0.941394 (rank : 98)
Query Neighborhood Hits	333	Target Neighborhood Hits	310	Shared Neighborhood Hits	199
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TMPS7_HUMAN
θ value	1.66964e-54 (rank : 18)	NC score	0.946909 (rank : 85)
Query Neighborhood Hits	333	Target Neighborhood Hits	275	Shared Neighborhood Hits	189
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS6_HUMAN
θ value	4.85792e-54 (rank : 19)	NC score	0.948342 (rank : 83)
Query Neighborhood Hits	333	Target Neighborhood Hits	338	Shared Neighborhood Hits	190
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

POLS2_MOUSE
θ value	3.1488e-53 (rank : 20)	NC score	0.977895 (rank : 39)
Query Neighborhood Hits	333	Target Neighborhood Hits	188	Shared Neighborhood Hits	174
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

CORIN_MOUSE
θ value	2.041e-52 (rank : 21)	NC score	0.866458 (rank : 158)
Query Neighborhood Hits	333	Target Neighborhood Hits	451	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

FA11_MOUSE
θ value	5.93839e-52 (rank : 22)	NC score	0.979372 (rank : 35)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	174
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

TM11E_MOUSE
θ value	1.01294e-51 (rank : 23)	NC score	0.981784 (rank : 28)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	173
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

FA11_HUMAN
θ value	2.94719e-51 (rank : 24)	NC score	0.978895 (rank : 36)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	174
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

TM11E_HUMAN
θ value	5.02714e-51 (rank : 25)	NC score	0.981809 (rank : 27)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

ST14_MOUSE
θ value	1.91031e-50 (rank : 26)	NC score	0.884879 (rank : 153)
Query Neighborhood Hits	333	Target Neighborhood Hits	419	Shared Neighborhood Hits	191
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ENTK_MOUSE
θ value	2.49495e-50 (rank : 27)	NC score	0.931047 (rank : 110)
Query Neighborhood Hits	333	Target Neighborhood Hits	338	Shared Neighborhood Hits	200
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

PRSS8_HUMAN
θ value	2.49495e-50 (rank : 28)	NC score	0.984204 (rank : 17)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

TEST_HUMAN
θ value	2.49495e-50 (rank : 29)	NC score	0.984509 (rank : 14)
Query Neighborhood Hits	333	Target Neighborhood Hits	172	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

CORIN_HUMAN
θ value	4.25575e-50 (rank : 30)	NC score	0.862546 (rank : 160)
Query Neighborhood Hits	333	Target Neighborhood Hits	453	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

TEST_MOUSE
θ value	4.70527e-49 (rank : 31)	NC score	0.984813 (rank : 13)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

NETR_HUMAN
θ value	2.3352e-48 (rank : 32)	NC score	0.898603 (rank : 149)
Query Neighborhood Hits	333	Target Neighborhood Hits	218	Shared Neighborhood Hits	186
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

POLS2_HUMAN
θ value	3.98324e-48 (rank : 33)	NC score	0.977292 (rank : 42)
Query Neighborhood Hits	333	Target Neighborhood Hits	192	Shared Neighborhood Hits	176
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

MCPT6_MOUSE
θ value	5.20228e-48 (rank : 34)	NC score	0.979744 (rank : 33)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

TMPS9_HUMAN
θ value	5.20228e-48 (rank : 35)	NC score	0.971748 (rank : 48)
Query Neighborhood Hits	333	Target Neighborhood Hits	276	Shared Neighborhood Hits	193
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

PRSS8_MOUSE
θ value	8.87376e-48 (rank : 36)	NC score	0.984454 (rank : 15)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

TRYG1_HUMAN
θ value	1.15895e-47 (rank : 37)	NC score	0.984050 (rank : 19)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

ST14_HUMAN
θ value	1.97686e-47 (rank : 38)	NC score	0.883659 (rank : 154)
Query Neighborhood Hits	333	Target Neighborhood Hits	409	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

PLMN_MOUSE
θ value	3.37202e-47 (rank : 39)	NC score	0.953310 (rank : 72)
Query Neighborhood Hits	333	Target Neighborhood Hits	208	Shared Neighborhood Hits	176
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

NETR_MOUSE
θ value	5.7518e-47 (rank : 40)	NC score	0.903735 (rank : 145)
Query Neighborhood Hits	333	Target Neighborhood Hits	216	Shared Neighborhood Hits	185
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

PRS27_HUMAN
θ value	9.81109e-47 (rank : 41)	NC score	0.983888 (rank : 21)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	1.28137e-46 (rank : 42)	NC score	0.983933 (rank : 20)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

TM11D_HUMAN
θ value	1.28137e-46 (rank : 43)	NC score	0.983236 (rank : 23)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	175
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TMPS9_MOUSE
θ value	1.28137e-46 (rank : 44)	NC score	0.971785 (rank : 46)
Query Neighborhood Hits	333	Target Neighborhood Hits	296	Shared Neighborhood Hits	197
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

PLMN_HUMAN
θ value	1.67352e-46 (rank : 45)	NC score	0.954093 (rank : 71)
Query Neighborhood Hits	333	Target Neighborhood Hits	204	Shared Neighborhood Hits	175
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

TRYB1_MOUSE
θ value	3.72821e-46 (rank : 46)	NC score	0.979730 (rank : 34)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYG1_MOUSE
θ value	4.86918e-46 (rank : 47)	NC score	0.984377 (rank : 16)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	175
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

DESC4_MOUSE
θ value	6.35935e-46 (rank : 48)	NC score	0.982764 (rank : 24)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	173
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

TRYB1_HUMAN
θ value	8.30557e-46 (rank : 49)	NC score	0.977374 (rank : 40)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
θ value	8.30557e-46 (rank : 50)	NC score	0.977374 (rank : 41)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

ACRO_MOUSE
θ value	1.19932e-44 (rank : 51)	NC score	0.983476 (rank : 22)
Query Neighborhood Hits	333	Target Neighborhood Hits	185	Shared Neighborhood Hits	174
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

APOA_HUMAN
θ value	4.55743e-44 (rank : 52)	NC score	0.944850 (rank : 89)
Query Neighborhood Hits	333	Target Neighborhood Hits	221	Shared Neighborhood Hits	177
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

TRYA1_HUMAN
θ value	1.01529e-43 (rank : 53)	NC score	0.976967 (rank : 43)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	176
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

ACRO_HUMAN
θ value	1.73182e-43 (rank : 54)	NC score	0.982258 (rank : 26)
Query Neighborhood Hits	333	Target Neighborhood Hits	291	Shared Neighborhood Hits	189
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TM11D_MOUSE
θ value	3.26607e-42 (rank : 55)	NC score	0.981416 (rank : 30)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	175
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TMSP8_MOUSE
θ value	3.26607e-42 (rank : 56)	NC score	0.984170 (rank : 18)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	175
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

BSSP4_HUMAN
θ value	1.3722e-40 (rank : 57)	NC score	0.982406 (rank : 25)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

HGFA_HUMAN
θ value	9.83387e-39 (rank : 58)	NC score	0.908284 (rank : 137)
Query Neighborhood Hits	333	Target Neighborhood Hits	436	Shared Neighborhood Hits	184
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TPA_MOUSE
θ value	3.73686e-38 (rank : 59)	NC score	0.943041 (rank : 91)
Query Neighborhood Hits	333	Target Neighborhood Hits	335	Shared Neighborhood Hits	180
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

UROK_HUMAN
θ value	8.32485e-38 (rank : 60)	NC score	0.959420 (rank : 66)
Query Neighborhood Hits	333	Target Neighborhood Hits	272	Shared Neighborhood Hits	175
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

BSSP4_MOUSE
θ value	1.08726e-37 (rank : 61)	NC score	0.981671 (rank : 29)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

FA12_HUMAN
θ value	1.85459e-37 (rank : 62)	NC score	0.916480 (rank : 127)
Query Neighborhood Hits	333	Target Neighborhood Hits	425	Shared Neighborhood Hits	181
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

HGFA_MOUSE
θ value	1.85459e-37 (rank : 63)	NC score	0.909236 (rank : 136)
Query Neighborhood Hits	333	Target Neighborhood Hits	419	Shared Neighborhood Hits	179
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ELA2A_HUMAN
θ value	3.16345e-37 (rank : 64)	NC score	0.971773 (rank : 47)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	175
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

CTRB1_HUMAN
θ value	4.13158e-37 (rank : 65)	NC score	0.978277 (rank : 37)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	175
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

ELA2A_MOUSE
θ value	9.20422e-37 (rank : 66)	NC score	0.973816 (rank : 45)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

TPA_HUMAN
θ value	1.20211e-36 (rank : 67)	NC score	0.942734 (rank : 95)
Query Neighborhood Hits	333	Target Neighborhood Hits	324	Shared Neighborhood Hits	178
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ELA1_HUMAN
θ value	2.05049e-36 (rank : 68)	NC score	0.968529 (rank : 51)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

FA10_MOUSE
θ value	4.568e-36 (rank : 69)	NC score	0.888517 (rank : 152)
Query Neighborhood Hits	333	Target Neighborhood Hits	435	Shared Neighborhood Hits	186
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PROC_MOUSE
θ value	1.32909e-35 (rank : 70)	NC score	0.906145 (rank : 143)
Query Neighborhood Hits	333	Target Neighborhood Hits	426	Shared Neighborhood Hits	187
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

K1KB9_MOUSE
θ value	1.73584e-35 (rank : 71)	NC score	0.942993 (rank : 92)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

TRY2_MOUSE
θ value	2.26708e-35 (rank : 72)	NC score	0.966871 (rank : 53)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

UROK_MOUSE
θ value	8.61488e-35 (rank : 73)	NC score	0.960405 (rank : 63)
Query Neighborhood Hits	333	Target Neighborhood Hits	273	Shared Neighborhood Hits	175
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

FA10_HUMAN
θ value	1.12514e-34 (rank : 74)	NC score	0.891638 (rank : 151)
Query Neighborhood Hits	333	Target Neighborhood Hits	431	Shared Neighborhood Hits	186
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CFAI_MOUSE
θ value	1.46948e-34 (rank : 75)	NC score	0.946042 (rank : 87)
Query Neighborhood Hits	333	Target Neighborhood Hits	290	Shared Neighborhood Hits	199
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

HABP2_MOUSE
θ value	1.9192e-34 (rank : 76)	NC score	0.877990 (rank : 156)
Query Neighborhood Hits	333	Target Neighborhood Hits	445	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_HUMAN
θ value	3.27365e-34 (rank : 77)	NC score	0.879582 (rank : 155)
Query Neighborhood Hits	333	Target Neighborhood Hits	431	Shared Neighborhood Hits	177
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

K1B11_MOUSE
θ value	4.27553e-34 (rank : 78)	NC score	0.942058 (rank : 96)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	174
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1KB1_MOUSE
θ value	5.584e-34 (rank : 79)	NC score	0.941861 (rank : 97)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	175
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

CTRL_HUMAN
θ value	7.29293e-34 (rank : 80)	NC score	0.978098 (rank : 38)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	175
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

K1KB3_MOUSE
θ value	7.29293e-34 (rank : 81)	NC score	0.940974 (rank : 99)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

FA7_MOUSE
θ value	1.24399e-33 (rank : 82)	NC score	0.919307 (rank : 123)
Query Neighborhood Hits	333	Target Neighborhood Hits	374	Shared Neighborhood Hits	183
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

TRY1_HUMAN
θ value	1.24399e-33 (rank : 83)	NC score	0.964294 (rank : 55)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

KLK13_HUMAN
θ value	1.6247e-33 (rank : 84)	NC score	0.960142 (rank : 64)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

PROC_HUMAN
θ value	3.61944e-33 (rank : 85)	NC score	0.919188 (rank : 124)
Query Neighborhood Hits	333	Target Neighborhood Hits	406	Shared Neighborhood Hits	185
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TRY3_HUMAN
θ value	6.17384e-33 (rank : 86)	NC score	0.963996 (rank : 57)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

ELA2B_HUMAN
θ value	8.06329e-33 (rank : 87)	NC score	0.969968 (rank : 50)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

FA9_HUMAN
θ value	8.06329e-33 (rank : 88)	NC score	0.903091 (rank : 146)
Query Neighborhood Hits	333	Target Neighborhood Hits	421	Shared Neighborhood Hits	183
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

KLK1_MOUSE
θ value	1.79631e-32 (rank : 89)	NC score	0.940543 (rank : 100)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

TRY2_HUMAN
θ value	5.22648e-32 (rank : 90)	NC score	0.965046 (rank : 54)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	173
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

K1KB5_MOUSE
θ value	1.16434e-31 (rank : 91)	NC score	0.936100 (rank : 105)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

CLCR_HUMAN
θ value	3.3877e-31 (rank : 92)	NC score	0.970827 (rank : 49)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

K1B22_MOUSE
θ value	4.42448e-31 (rank : 93)	NC score	0.938260 (rank : 102)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

FA7_HUMAN
θ value	5.77852e-31 (rank : 94)	NC score	0.907178 (rank : 140)
Query Neighborhood Hits	333	Target Neighborhood Hits	404	Shared Neighborhood Hits	184
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

KLK6_HUMAN
θ value	5.77852e-31 (rank : 95)	NC score	0.960848 (rank : 61)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

THRB_HUMAN
θ value	7.54701e-31 (rank : 96)	NC score	0.944106 (rank : 90)
Query Neighborhood Hits	333	Target Neighborhood Hits	196	Shared Neighborhood Hits	174
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

KLK11_HUMAN
θ value	9.8567e-31 (rank : 97)	NC score	0.952407 (rank : 76)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

THRB_MOUSE
θ value	9.8567e-31 (rank : 98)	NC score	0.944907 (rank : 88)
Query Neighborhood Hits	333	Target Neighborhood Hits	195	Shared Neighborhood Hits	174
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TRYD_HUMAN
θ value	2.19584e-30 (rank : 99)	NC score	0.968250 (rank : 52)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TSP50_HUMAN
θ value	2.19584e-30 (rank : 100)	NC score	0.975569 (rank : 44)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

MASP2_HUMAN
θ value	3.74554e-30 (rank : 101)	NC score	0.856694 (rank : 162)
Query Neighborhood Hits	333	Target Neighborhood Hits	364	Shared Neighborhood Hits	183
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

K1B26_MOUSE
θ value	4.89182e-30 (rank : 102)	NC score	0.934152 (rank : 107)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B24_MOUSE
θ value	8.3442e-30 (rank : 103)	NC score	0.938346 (rank : 101)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	174
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B21_MOUSE
θ value	1.08979e-29 (rank : 104)	NC score	0.936376 (rank : 104)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	175
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

KLK7_MOUSE
θ value	1.4233e-29 (rank : 105)	NC score	0.956461 (rank : 67)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

K1KB4_MOUSE
θ value	2.42779e-29 (rank : 106)	NC score	0.929897 (rank : 112)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

GRAK_MOUSE
θ value	3.17079e-29 (rank : 107)	NC score	0.960412 (rank : 62)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	173
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

KLK11_MOUSE
θ value	3.17079e-29 (rank : 108)	NC score	0.951331 (rank : 78)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

K1KB8_MOUSE
θ value	5.40856e-29 (rank : 109)	NC score	0.932657 (rank : 109)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

CFAI_HUMAN
θ value	9.2256e-29 (rank : 110)	NC score	0.942763 (rank : 93)
Query Neighborhood Hits	333	Target Neighborhood Hits	289	Shared Neighborhood Hits	199
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

EGFB2_MOUSE
θ value	1.2049e-28 (rank : 111)	NC score	0.933497 (rank : 108)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

K1B27_MOUSE
θ value	1.57365e-28 (rank : 112)	NC score	0.937534 (rank : 103)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

NRPN_MOUSE
θ value	1.57365e-28 (rank : 113)	NC score	0.949213 (rank : 82)
Query Neighborhood Hits	333	Target Neighborhood Hits	186	Shared Neighborhood Hits	174
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

KLK7_HUMAN
θ value	2.05525e-28 (rank : 114)	NC score	0.955297 (rank : 69)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK12_HUMAN
θ value	7.80994e-28 (rank : 115)	NC score	0.954945 (rank : 70)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

NRPN_HUMAN
θ value	7.80994e-28 (rank : 116)	NC score	0.953246 (rank : 74)
Query Neighborhood Hits	333	Target Neighborhood Hits	182	Shared Neighborhood Hits	174
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

CFAD_MOUSE
θ value	1.02001e-27 (rank : 117)	NC score	0.964024 (rank : 56)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

HGF_MOUSE
θ value	1.02001e-27 (rank : 118)	NC score	0.916008 (rank : 128)
Query Neighborhood Hits	333	Target Neighborhood Hits	192	Shared Neighborhood Hits	171
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

MASP2_MOUSE
θ value	1.02001e-27 (rank : 119)	NC score	0.857806 (rank : 161)
Query Neighborhood Hits	333	Target Neighborhood Hits	382	Shared Neighborhood Hits	182
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

KLK1_HUMAN
θ value	1.33217e-27 (rank : 120)	NC score	0.935299 (rank : 106)
Query Neighborhood Hits	333	Target Neighborhood Hits	183	Shared Neighborhood Hits	174
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

MASP1_HUMAN
θ value	1.73987e-27 (rank : 121)	NC score	0.864490 (rank : 159)
Query Neighborhood Hits	333	Target Neighborhood Hits	369	Shared Neighborhood Hits	182
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

C1RA_MOUSE
θ value	2.27234e-27 (rank : 122)	NC score	0.831690 (rank : 168)
Query Neighborhood Hits	333	Target Neighborhood Hits	379	Shared Neighborhood Hits	184
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

CFAD_HUMAN
θ value	2.27234e-27 (rank : 123)	NC score	0.959589 (rank : 65)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

KLK2_HUMAN
θ value	5.06226e-27 (rank : 124)	NC score	0.946072 (rank : 86)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

C1RB_MOUSE
θ value	8.63488e-27 (rank : 125)	NC score	0.836562 (rank : 166)
Query Neighborhood Hits	333	Target Neighborhood Hits	380	Shared Neighborhood Hits	184
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

KLK14_HUMAN
θ value	8.63488e-27 (rank : 126)	NC score	0.955875 (rank : 68)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

MASP1_MOUSE
θ value	1.12775e-26 (rank : 127)	NC score	0.868961 (rank : 157)
Query Neighborhood Hits	333	Target Neighborhood Hits	364	Shared Neighborhood Hits	182
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

KLK3_HUMAN
θ value	2.51237e-26 (rank : 128)	NC score	0.942741 (rank : 94)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	175
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

ELA3A_HUMAN
θ value	3.28125e-26 (rank : 129)	NC score	0.962224 (rank : 58)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	173
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	5.59698e-26 (rank : 130)	NC score	0.961462 (rank : 59)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	173
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

C1R_HUMAN
θ value	7.30988e-26 (rank : 131)	NC score	0.835587 (rank : 167)
Query Neighborhood Hits	333	Target Neighborhood Hits	364	Shared Neighborhood Hits	180
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

KLK15_HUMAN
θ value	9.54697e-26 (rank : 132)	NC score	0.953248 (rank : 73)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	174
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

HGF_HUMAN
θ value	3.62785e-25 (rank : 133)	NC score	0.915989 (rank : 129)
Query Neighborhood Hits	333	Target Neighborhood Hits	191	Shared Neighborhood Hits	171
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

KLK9_HUMAN
θ value	4.73814e-25 (rank : 134)	NC score	0.950223 (rank : 81)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLK5_HUMAN
θ value	1.05554e-24 (rank : 135)	NC score	0.951791 (rank : 77)
Query Neighborhood Hits	333	Target Neighborhood Hits	182	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

C1S_HUMAN
θ value	1.80048e-24 (rank : 136)	NC score	0.842301 (rank : 165)
Query Neighborhood Hits	333	Target Neighborhood Hits	359	Shared Neighborhood Hits	180
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

HGFL_MOUSE
θ value	2.35151e-24 (rank : 137)	NC score	0.922372 (rank : 118)
Query Neighborhood Hits	333	Target Neighborhood Hits	188	Shared Neighborhood Hits	172
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

KLK10_HUMAN
θ value	4.01107e-24 (rank : 138)	NC score	0.950596 (rank : 80)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	174
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

GRAF_MOUSE
θ value	1.99067e-23 (rank : 139)	NC score	0.919167 (rank : 125)
Query Neighborhood Hits	333	Target Neighborhood Hits	172	Shared Neighborhood Hits	172
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

GRAM_HUMAN
θ value	7.56453e-23 (rank : 140)	NC score	0.961144 (rank : 60)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

CS1B_MOUSE
θ value	1.29031e-22 (rank : 141)	NC score	0.847054 (rank : 163)
Query Neighborhood Hits	333	Target Neighborhood Hits	361	Shared Neighborhood Hits	181
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

HGFL_HUMAN
θ value	1.6852e-22 (rank : 142)	NC score	0.921330 (rank : 121)
Query Neighborhood Hits	333	Target Neighborhood Hits	190	Shared Neighborhood Hits	173
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

K1B16_MOUSE
θ value	4.9032e-22 (rank : 143)	NC score	0.916725 (rank : 126)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	174
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

CS1A_MOUSE
θ value	4.15078e-21 (rank : 144)	NC score	0.842877 (rank : 164)
Query Neighborhood Hits	333	Target Neighborhood Hits	360	Shared Neighborhood Hits	180
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

KLK4_HUMAN
θ value	1.2077e-20 (rank : 145)	NC score	0.950985 (rank : 79)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

MCPT2_MOUSE
θ value	1.5773e-20 (rank : 146)	NC score	0.926045 (rank : 113)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MCPT1_MOUSE
θ value	5.99374e-20 (rank : 147)	NC score	0.923452 (rank : 116)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

GRAG_MOUSE
θ value	7.82807e-20 (rank : 148)	NC score	0.912461 (rank : 132)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	172
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

MCPT4_MOUSE
θ value	2.27762e-19 (rank : 149)	NC score	0.921447 (rank : 120)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

GRAD_MOUSE
θ value	8.65492e-19 (rank : 150)	NC score	0.906731 (rank : 142)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	171
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

PRTN3_HUMAN
θ value	8.65492e-19 (rank : 151)	NC score	0.924613 (rank : 114)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	172
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

CATG_MOUSE
θ value	1.47631e-18 (rank : 152)	NC score	0.930616 (rank : 111)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

GRAE_MOUSE
θ value	1.47631e-18 (rank : 153)	NC score	0.907480 (rank : 139)
Query Neighborhood Hits	333	Target Neighborhood Hits	172	Shared Neighborhood Hits	171
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

PRTN3_MOUSE
θ value	2.13179e-17 (rank : 154)	NC score	0.920116 (rank : 122)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	Q61096, O08809	Gene names	Prtn3
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Proteinase 3) (PR-3).

CATG_HUMAN
θ value	4.74913e-17 (rank : 155)	NC score	0.924294 (rank : 115)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

GRAC_MOUSE
θ value	8.10077e-17 (rank : 156)	NC score	0.914989 (rank : 130)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	173
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

MCPT9_MOUSE
θ value	1.058e-16 (rank : 157)	NC score	0.912418 (rank : 133)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

HPT_HUMAN
θ value	6.85773e-16 (rank : 158)	NC score	0.899870 (rank : 148)
Query Neighborhood Hits	333	Target Neighborhood Hits	184	Shared Neighborhood Hits	164
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

MCPT1_HUMAN
θ value	8.95645e-16 (rank : 159)	NC score	0.910069 (rank : 134)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	173
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

MCPTX_MOUSE
θ value	1.16975e-15 (rank : 160)	NC score	0.912963 (rank : 131)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q00356	Gene names	Mcptl
Domain Architecture
Description	Mast cell protease-like protein precursor (EC 3.4.21.-).

HPTR_HUMAN
θ value	4.44505e-15 (rank : 161)	NC score	0.900646 (rank : 147)
Query Neighborhood Hits	333	Target Neighborhood Hits	166	Shared Neighborhood Hits	164
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

GRAH_HUMAN
θ value	9.90251e-15 (rank : 162)	NC score	0.922070 (rank : 119)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

ELNE_MOUSE
θ value	1.29331e-14 (rank : 163)	NC score	0.908240 (rank : 138)
Query Neighborhood Hits	333	Target Neighborhood Hits	167	Shared Neighborhood Hits	163
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

MCPT8_MOUSE
θ value	1.68911e-14 (rank : 164)	NC score	0.903977 (rank : 144)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

HPT_MOUSE
θ value	2.88119e-14 (rank : 165)	NC score	0.909840 (rank : 135)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	169
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

CAP7_HUMAN
θ value	6.41864e-14 (rank : 166)	NC score	0.923035 (rank : 117)
Query Neighborhood Hits	333	Target Neighborhood Hits	169	Shared Neighborhood Hits	169
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

CFAB_MOUSE
θ value	8.38298e-14 (rank : 167)	NC score	0.733582 (rank : 172)
Query Neighborhood Hits	333	Target Neighborhood Hits	262	Shared Neighborhood Hits	168
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO2_MOUSE
θ value	7.09661e-13 (rank : 168)	NC score	0.784707 (rank : 169)
Query Neighborhood Hits	333	Target Neighborhood Hits	250	Shared Neighborhood Hits	170
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

ELNE_HUMAN
θ value	2.0648e-12 (rank : 169)	NC score	0.907016 (rank : 141)
Query Neighborhood Hits	333	Target Neighborhood Hits	164	Shared Neighborhood Hits	163
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

CFAB_HUMAN
θ value	1.33837e-11 (rank : 170)	NC score	0.743869 (rank : 171)
Query Neighborhood Hits	333	Target Neighborhood Hits	251	Shared Neighborhood Hits	168
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO2_HUMAN
θ value	1.74796e-11 (rank : 171)	NC score	0.745014 (rank : 170)
Query Neighborhood Hits	333	Target Neighborhood Hits	258	Shared Neighborhood Hits	173
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

MCPT5_MOUSE
θ value	9.59137e-10 (rank : 172)	NC score	0.892570 (rank : 150)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P21844, Q9R1F0	Gene names	Mcpt5
Domain Architecture
Description	Mast cell protease 5 precursor (EC 3.4.21.-) (MMCP-5) (Mast cell chymase 1).

OGFR_HUMAN
θ value	2.21117e-06 (rank : 173)	NC score	0.024369 (rank : 293)
Query Neighborhood Hits	333	Target Neighborhood Hits	1582	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NACAM_MOUSE
θ value	0.000270298 (rank : 174)	NC score	0.026667 (rank : 292)
Query Neighborhood Hits	333	Target Neighborhood Hits	1866	Shared Neighborhood Hits	107
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NFH_MOUSE
θ value	0.000602161 (rank : 175)	NC score	0.005504 (rank : 370)
Query Neighborhood Hits	333	Target Neighborhood Hits	2247	Shared Neighborhood Hits	91
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PROZ_MOUSE
θ value	0.000602161 (rank : 176)	NC score	0.523183 (rank : 174)
Query Neighborhood Hits	333	Target Neighborhood Hits	410	Shared Neighborhood Hits	169
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_HUMAN
θ value	0.000786445 (rank : 177)	NC score	0.553465 (rank : 173)
Query Neighborhood Hits	333	Target Neighborhood Hits	422	Shared Neighborhood Hits	173
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TARA_HUMAN
θ value	0.000786445 (rank : 178)	NC score	0.022677 (rank : 297)
Query Neighborhood Hits	333	Target Neighborhood Hits	1626	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MUC1_HUMAN
θ value	0.0113563 (rank : 179)	NC score	0.013625 (rank : 322)
Query Neighborhood Hits	333	Target Neighborhood Hits	975	Shared Neighborhood Hits	65
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

LSD1_HUMAN
θ value	0.0193708 (rank : 180)	NC score	0.017762 (rank : 309)
Query Neighborhood Hits	333	Target Neighborhood Hits	455	Shared Neighborhood Hits	23
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

PHC2_HUMAN
θ value	0.0252991 (rank : 181)	NC score	0.020252 (rank : 302)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PCLO_MOUSE
θ value	0.0330416 (rank : 182)	NC score	0.016025 (rank : 313)
Query Neighborhood Hits	333	Target Neighborhood Hits	2275	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MK15_HUMAN
θ value	0.0431538 (rank : 183)	NC score	-0.007396 (rank : 416)
Query Neighborhood Hits	333	Target Neighborhood Hits	1038	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

BSN_MOUSE
θ value	0.0736092 (rank : 184)	NC score	0.020157 (rank : 303)
Query Neighborhood Hits	333	Target Neighborhood Hits	2057	Shared Neighborhood Hits	106
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GRIP2_HUMAN
θ value	0.0736092 (rank : 185)	NC score	0.005328 (rank : 371)
Query Neighborhood Hits	333	Target Neighborhood Hits	256	Shared Neighborhood Hits	12
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

SC24C_HUMAN
θ value	0.0736092 (rank : 186)	NC score	0.012873 (rank : 324)
Query Neighborhood Hits	333	Target Neighborhood Hits	662	Shared Neighborhood Hits	49
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SELPL_MOUSE
θ value	0.0736092 (rank : 187)	NC score	0.023922 (rank : 294)
Query Neighborhood Hits	333	Target Neighborhood Hits	588	Shared Neighborhood Hits	56
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

NCOA2_MOUSE
θ value	0.0961366 (rank : 188)	NC score	0.015130 (rank : 315)
Query Neighborhood Hits	333	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

ASTL_HUMAN
θ value	0.125558 (rank : 189)	NC score	0.010266 (rank : 343)
Query Neighborhood Hits	333	Target Neighborhood Hits	252	Shared Neighborhood Hits	21
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

GTSE1_MOUSE
θ value	0.125558 (rank : 190)	NC score	0.022797 (rank : 296)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

PHC2_MOUSE
θ value	0.125558 (rank : 191)	NC score	0.020512 (rank : 301)
Query Neighborhood Hits	333	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

RGS3_MOUSE
θ value	0.125558 (rank : 192)	NC score	0.007444 (rank : 356)
Query Neighborhood Hits	333	Target Neighborhood Hits	1621	Shared Neighborhood Hits	81
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SPEG_HUMAN
θ value	0.125558 (rank : 193)	NC score	-0.005860 (rank : 413)
Query Neighborhood Hits	333	Target Neighborhood Hits	1762	Shared Neighborhood Hits	68
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

RFIP5_MOUSE
θ value	0.163984 (rank : 194)	NC score	0.013991 (rank : 317)
Query Neighborhood Hits	333	Target Neighborhood Hits	126	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

AFF4_MOUSE
θ value	0.21417 (rank : 195)	NC score	0.012326 (rank : 329)
Query Neighborhood Hits	333	Target Neighborhood Hits	581	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

FOXE2_HUMAN
θ value	0.21417 (rank : 196)	NC score	0.003625 (rank : 382)
Query Neighborhood Hits	333	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

RP1L1_HUMAN
θ value	0.21417 (rank : 197)	NC score	0.012060 (rank : 332)
Query Neighborhood Hits	333	Target Neighborhood Hits	1072	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SRRM2_MOUSE
θ value	0.21417 (rank : 198)	NC score	0.019847 (rank : 304)
Query Neighborhood Hits	333	Target Neighborhood Hits	1470	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

LAD1_HUMAN
θ value	0.279714 (rank : 199)	NC score	0.014377 (rank : 316)
Query Neighborhood Hits	333	Target Neighborhood Hits	441	Shared Neighborhood Hits	34
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SF3B1_HUMAN
θ value	0.279714 (rank : 200)	NC score	0.021888 (rank : 299)
Query Neighborhood Hits	333	Target Neighborhood Hits	341	Shared Neighborhood Hits	37
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.279714 (rank : 201)	NC score	0.021854 (rank : 300)
Query Neighborhood Hits	333	Target Neighborhood Hits	352	Shared Neighborhood Hits	37
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TBX3_MOUSE
θ value	0.279714 (rank : 202)	NC score	0.003616 (rank : 383)
Query Neighborhood Hits	333	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

C163B_HUMAN
θ value	0.365318 (rank : 203)	NC score	0.084187 (rank : 229)
Query Neighborhood Hits	333	Target Neighborhood Hits	64	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

IL3B2_MOUSE
θ value	0.365318 (rank : 204)	NC score	0.012430 (rank : 327)
Query Neighborhood Hits	333	Target Neighborhood Hits	372	Shared Neighborhood Hits	27
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_MOUSE
θ value	0.365318 (rank : 205)	NC score	0.013790 (rank : 318)
Query Neighborhood Hits	333	Target Neighborhood Hits	355	Shared Neighborhood Hits	28
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

MAGE1_HUMAN
θ value	0.365318 (rank : 206)	NC score	0.005270 (rank : 372)
Query Neighborhood Hits	333	Target Neighborhood Hits	1389	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PHF12_MOUSE
θ value	0.365318 (rank : 207)	NC score	0.010559 (rank : 339)
Query Neighborhood Hits	333	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

RGS3_HUMAN
θ value	0.365318 (rank : 208)	NC score	0.005057 (rank : 374)
Query Neighborhood Hits	333	Target Neighborhood Hits	1375	Shared Neighborhood Hits	68
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

S6A18_HUMAN
θ value	0.365318 (rank : 209)	NC score	0.004168 (rank : 379)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q96N87	Gene names	SLC6A18, XTRP2
Domain Architecture
Description	Sodium- and chloride-dependent transporter XTRP2 (Solute carrier family 6 member 18).

ZN541_HUMAN
θ value	0.365318 (rank : 210)	NC score	0.012026 (rank : 334)
Query Neighborhood Hits	333	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

BIN1_HUMAN
θ value	0.47712 (rank : 211)	NC score	0.013754 (rank : 319)
Query Neighborhood Hits	333	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

HRBL_MOUSE
θ value	0.47712 (rank : 212)	NC score	0.006663 (rank : 361)
Query Neighborhood Hits	333	Target Neighborhood Hits	269	Shared Neighborhood Hits	19
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

SPEG_MOUSE
θ value	0.47712 (rank : 213)	NC score	-0.005467 (rank : 411)
Query Neighborhood Hits	333	Target Neighborhood Hits	1959	Shared Neighborhood Hits	72
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRRM1_MOUSE
θ value	0.47712 (rank : 214)	NC score	0.023541 (rank : 295)
Query Neighborhood Hits	333	Target Neighborhood Hits	966	Shared Neighborhood Hits	75
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BAP1_HUMAN
θ value	0.62314 (rank : 215)	NC score	0.012641 (rank : 326)
Query Neighborhood Hits	333	Target Neighborhood Hits	106	Shared Neighborhood Hits	14
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

FOXK2_HUMAN
θ value	0.62314 (rank : 216)	NC score	0.002459 (rank : 388)
Query Neighborhood Hits	333	Target Neighborhood Hits	190	Shared Neighborhood Hits	13
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

BIN1_MOUSE
θ value	0.813845 (rank : 217)	NC score	0.012861 (rank : 325)
Query Neighborhood Hits	333	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

FOG1_MOUSE
θ value	0.813845 (rank : 218)	NC score	-0.005661 (rank : 412)
Query Neighborhood Hits	333	Target Neighborhood Hits	1237	Shared Neighborhood Hits	57
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PRS23_HUMAN
θ value	0.813845 (rank : 219)	NC score	0.129752 (rank : 184)
Query Neighborhood Hits	333	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	O95084	Gene names	PRSS23, ZSIG13
Domain Architecture
Description	Serine protease 23 precursor (EC 3.4.21.-) (Putative secreted protein ZSIG13).

PTPRG_MOUSE
θ value	0.813845 (rank : 220)	NC score	0.000998 (rank : 397)
Query Neighborhood Hits	333	Target Neighborhood Hits	260	Shared Neighborhood Hits	13
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

ZFHX2_HUMAN
θ value	0.813845 (rank : 221)	NC score	-0.005454 (rank : 410)
Query Neighborhood Hits	333	Target Neighborhood Hits	1178	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

CRSP2_HUMAN
θ value	1.06291 (rank : 222)	NC score	0.017434 (rank : 310)
Query Neighborhood Hits	333	Target Neighborhood Hits	380	Shared Neighborhood Hits	40
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

DOS_HUMAN
θ value	1.06291 (rank : 223)	NC score	0.016201 (rank : 311)
Query Neighborhood Hits	333	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

SORL_HUMAN
θ value	1.06291 (rank : 224)	NC score	0.095376 (rank : 220)
Query Neighborhood Hits	333	Target Neighborhood Hits	440	Shared Neighborhood Hits	40
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	1.06291 (rank : 225)	NC score	0.098827 (rank : 218)
Query Neighborhood Hits	333	Target Neighborhood Hits	439	Shared Neighborhood Hits	42
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TARA_MOUSE
θ value	1.06291 (rank : 226)	NC score	0.018092 (rank : 308)
Query Neighborhood Hits	333	Target Neighborhood Hits	1133	Shared Neighborhood Hits	62
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZC3H6_MOUSE
θ value	1.06291 (rank : 227)	NC score	0.006360 (rank : 365)
Query Neighborhood Hits	333	Target Neighborhood Hits	239	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

C163A_HUMAN
θ value	1.38821 (rank : 228)	NC score	0.068260 (rank : 264)
Query Neighborhood Hits	333	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

C163A_MOUSE
θ value	1.38821 (rank : 229)	NC score	0.070533 (rank : 260)
Query Neighborhood Hits	333	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

INVS_MOUSE
θ value	1.38821 (rank : 230)	NC score	-0.000739 (rank : 405)
Query Neighborhood Hits	333	Target Neighborhood Hits	609	Shared Neighborhood Hits	42
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

NCOA2_HUMAN
θ value	1.38821 (rank : 231)	NC score	0.010871 (rank : 336)
Query Neighborhood Hits	333	Target Neighborhood Hits	281	Shared Neighborhood Hits	21
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PDZD2_HUMAN
θ value	1.38821 (rank : 232)	NC score	0.010737 (rank : 338)
Query Neighborhood Hits	333	Target Neighborhood Hits	772	Shared Neighborhood Hits	52
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PO210_HUMAN
θ value	1.38821 (rank : 233)	NC score	0.006573 (rank : 363)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEM1, O94980, Q6NXG6, Q8NBJ1, Q9H6C8, Q9UFP3	Gene names	NUP210, KIAA0906
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210 precursor (POM210) (Nuclear pore protein gp210).

STK10_HUMAN
θ value	1.38821 (rank : 234)	NC score	-0.014134 (rank : 424)
Query Neighborhood Hits	333	Target Neighborhood Hits	1921	Shared Neighborhood Hits	34
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BAG3_MOUSE
θ value	1.81305 (rank : 235)	NC score	0.013640 (rank : 321)
Query Neighborhood Hits	333	Target Neighborhood Hits	513	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BCLF1_MOUSE
θ value	1.81305 (rank : 236)	NC score	0.010505 (rank : 341)
Query Neighborhood Hits	333	Target Neighborhood Hits	303	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

GAK_HUMAN
θ value	1.81305 (rank : 237)	NC score	-0.009333 (rank : 419)
Query Neighborhood Hits	333	Target Neighborhood Hits	1028	Shared Neighborhood Hits	22
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

LDLR_MOUSE
θ value	1.81305 (rank : 238)	NC score	0.101043 (rank : 205)
Query Neighborhood Hits	333	Target Neighborhood Hits	382	Shared Neighborhood Hits	56
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MAGD4_HUMAN
θ value	1.81305 (rank : 239)	NC score	0.007994 (rank : 352)
Query Neighborhood Hits	333	Target Neighborhood Hits	338	Shared Neighborhood Hits	34
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MBB1A_HUMAN
θ value	1.81305 (rank : 240)	NC score	0.009722 (rank : 348)
Query Neighborhood Hits	333	Target Neighborhood Hits	665	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MINT_MOUSE
θ value	1.81305 (rank : 241)	NC score	0.006959 (rank : 359)
Query Neighborhood Hits	333	Target Neighborhood Hits	1514	Shared Neighborhood Hits	71
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SMOO_HUMAN
θ value	1.81305 (rank : 242)	NC score	0.010558 (rank : 340)
Query Neighborhood Hits	333	Target Neighborhood Hits	391	Shared Neighborhood Hits	40
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

ADA19_HUMAN
θ value	2.36792 (rank : 243)	NC score	0.001461 (rank : 394)
Query Neighborhood Hits	333	Target Neighborhood Hits	381	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

BSN_HUMAN
θ value	2.36792 (rank : 244)	NC score	0.019233 (rank : 305)
Query Neighborhood Hits	333	Target Neighborhood Hits	1537	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CT151_HUMAN
θ value	2.36792 (rank : 245)	NC score	0.016084 (rank : 312)
Query Neighborhood Hits	333	Target Neighborhood Hits	382	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

DDX51_HUMAN
θ value	2.36792 (rank : 246)	NC score	-0.000059 (rank : 404)
Query Neighborhood Hits	333	Target Neighborhood Hits	332	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

EVL_MOUSE
θ value	2.36792 (rank : 247)	NC score	0.009806 (rank : 347)
Query Neighborhood Hits	333	Target Neighborhood Hits	203	Shared Neighborhood Hits	26
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

LDLR_HUMAN
θ value	2.36792 (rank : 248)	NC score	0.099850 (rank : 212)
Query Neighborhood Hits	333	Target Neighborhood Hits	375	Shared Neighborhood Hits	58
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP6_HUMAN
θ value	2.36792 (rank : 249)	NC score	0.099761 (rank : 213)
Query Neighborhood Hits	333	Target Neighborhood Hits	235	Shared Neighborhood Hits	54
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	2.36792 (rank : 250)	NC score	0.099198 (rank : 217)
Query Neighborhood Hits	333	Target Neighborhood Hits	232	Shared Neighborhood Hits	53
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MAP4_MOUSE
θ value	2.36792 (rank : 251)	NC score	0.018811 (rank : 306)
Query Neighborhood Hits	333	Target Neighborhood Hits	409	Shared Neighborhood Hits	47
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAST4_HUMAN
θ value	2.36792 (rank : 252)	NC score	-0.007834 (rank : 417)
Query Neighborhood Hits	333	Target Neighborhood Hits	1804	Shared Neighborhood Hits	76
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PGBM_HUMAN
θ value	2.36792 (rank : 253)	NC score	0.059393 (rank : 270)
Query Neighborhood Hits	333	Target Neighborhood Hits	1113	Shared Neighborhood Hits	69
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PPRB_HUMAN
θ value	2.36792 (rank : 254)	NC score	0.013645 (rank : 320)
Query Neighborhood Hits	333	Target Neighborhood Hits	311	Shared Neighborhood Hits	36
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

APC_HUMAN
θ value	3.0926 (rank : 255)	NC score	0.012163 (rank : 330)
Query Neighborhood Hits	333	Target Neighborhood Hits	603	Shared Neighborhood Hits	41
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CIC_MOUSE
θ value	3.0926 (rank : 256)	NC score	0.011323 (rank : 335)
Query Neighborhood Hits	333	Target Neighborhood Hits	742	Shared Neighborhood Hits	68
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LRP2_HUMAN
θ value	3.0926 (rank : 257)	NC score	0.115395 (rank : 190)
Query Neighborhood Hits	333	Target Neighborhood Hits	573	Shared Neighborhood Hits	71
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

MAML1_MOUSE
θ value	3.0926 (rank : 258)	NC score	0.007325 (rank : 357)
Query Neighborhood Hits	333	Target Neighborhood Hits	279	Shared Neighborhood Hits	30
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MLL3_HUMAN
θ value	3.0926 (rank : 259)	NC score	-0.000028 (rank : 403)
Query Neighborhood Hits	333	Target Neighborhood Hits	1644	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MY18B_HUMAN
θ value	3.0926 (rank : 260)	NC score	-0.006223 (rank : 414)
Query Neighborhood Hits	333	Target Neighborhood Hits	1299	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

RRBP1_MOUSE
θ value	3.0926 (rank : 261)	NC score	-0.008369 (rank : 418)
Query Neighborhood Hits	333	Target Neighborhood Hits	1650	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SC6A5_MOUSE
θ value	3.0926 (rank : 262)	NC score	0.001507 (rank : 393)
Query Neighborhood Hits	333	Target Neighborhood Hits	135	Shared Neighborhood Hits	17
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

UBP36_HUMAN
θ value	3.0926 (rank : 263)	NC score	0.008071 (rank : 351)
Query Neighborhood Hits	333	Target Neighborhood Hits	232	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

ZN750_MOUSE
θ value	3.0926 (rank : 264)	NC score	0.013166 (rank : 323)
Query Neighborhood Hits	333	Target Neighborhood Hits	346	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

BAP1_MOUSE
θ value	4.03905 (rank : 265)	NC score	0.010204 (rank : 344)
Query Neighborhood Hits	333	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

DACT1_HUMAN
θ value	4.03905 (rank : 266)	NC score	0.012421 (rank : 328)
Query Neighborhood Hits	333	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

DNL1_HUMAN
θ value	4.03905 (rank : 267)	NC score	0.007787 (rank : 353)
Query Neighborhood Hits	333	Target Neighborhood Hits	216	Shared Neighborhood Hits	21
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

EVL_HUMAN
θ value	4.03905 (rank : 268)	NC score	0.009564 (rank : 349)
Query Neighborhood Hits	333	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

ITA7_HUMAN
θ value	4.03905 (rank : 269)	NC score	0.000867 (rank : 399)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q13683, O43197, Q9NY89, Q9UET0, Q9UEV2	Gene names	ITGA7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

K1802_MOUSE
θ value	4.03905 (rank : 270)	NC score	0.003105 (rank : 385)
Query Neighborhood Hits	333	Target Neighborhood Hits	1596	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LOXL3_HUMAN
θ value	4.03905 (rank : 271)	NC score	0.051951 (rank : 288)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P58215, Q96RS1	Gene names	LOXL3, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3).

LOXL4_HUMAN
θ value	4.03905 (rank : 272)	NC score	0.057399 (rank : 272)
Query Neighborhood Hits	333	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JB6, Q96DY1, Q96PC0, Q9H6T5	Gene names	LOXL4, LOXC
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LOXL4_MOUSE
θ value	4.03905 (rank : 273)	NC score	0.054803 (rank : 280)
Query Neighborhood Hits	333	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q924C6	Gene names	Loxl4, Loxc
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

MCM2_HUMAN
θ value	4.03905 (rank : 274)	NC score	0.001184 (rank : 395)
Query Neighborhood Hits	333	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7	Gene names	MCM2, BM28, CDCL1, KIAA0030
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

MSRE_HUMAN
θ value	4.03905 (rank : 275)	NC score	0.037580 (rank : 291)
Query Neighborhood Hits	333	Target Neighborhood Hits	298	Shared Neighborhood Hits	21
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

PHF12_HUMAN
θ value	4.03905 (rank : 276)	NC score	0.007783 (rank : 354)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PI5PA_HUMAN
θ value	4.03905 (rank : 277)	NC score	0.010760 (rank : 337)
Query Neighborhood Hits	333	Target Neighborhood Hits	749	Shared Neighborhood Hits	61
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

S23IP_MOUSE
θ value	4.03905 (rank : 278)	NC score	0.006607 (rank : 362)
Query Neighborhood Hits	333	Target Neighborhood Hits	363	Shared Neighborhood Hits	30
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SAPS1_HUMAN
θ value	4.03905 (rank : 279)	NC score	0.006556 (rank : 364)
Query Neighborhood Hits	333	Target Neighborhood Hits	704	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

WNK2_HUMAN
θ value	4.03905 (rank : 280)	NC score	-0.006926 (rank : 415)
Query Neighborhood Hits	333	Target Neighborhood Hits	1407	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

BAT2_MOUSE
θ value	5.27518 (rank : 281)	NC score	0.010344 (rank : 342)
Query Neighborhood Hits	333	Target Neighborhood Hits	947	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CBP_MOUSE
θ value	5.27518 (rank : 282)	NC score	0.007702 (rank : 355)
Query Neighborhood Hits	333	Target Neighborhood Hits	1051	Shared Neighborhood Hits	75
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DEN1A_MOUSE
θ value	5.27518 (rank : 283)	NC score	0.005504 (rank : 369)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

GRIN2_HUMAN
θ value	5.27518 (rank : 284)	NC score	0.012112 (rank : 331)
Query Neighborhood Hits	333	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

ITA7_MOUSE
θ value	5.27518 (rank : 285)	NC score	0.000750 (rank : 400)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q61738, O88731, O88732, P70350, Q61737, Q61741	Gene names	Itga7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

JPH2_HUMAN
θ value	5.27518 (rank : 286)	NC score	0.005013 (rank : 375)
Query Neighborhood Hits	333	Target Neighborhood Hits	639	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LRP5_MOUSE
θ value	5.27518 (rank : 287)	NC score	0.086861 (rank : 226)
Query Neighborhood Hits	333	Target Neighborhood Hits	236	Shared Neighborhood Hits	45
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MUC1_MOUSE
θ value	5.27518 (rank : 288)	NC score	0.022331 (rank : 298)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NCOR2_HUMAN
θ value	5.27518 (rank : 289)	NC score	0.009973 (rank : 346)
Query Neighborhood Hits	333	Target Neighborhood Hits	870	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NQO1_HUMAN
θ value	5.27518 (rank : 290)	NC score	0.005871 (rank : 367)
Query Neighborhood Hits	333	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P15559, Q86UK1	Gene names	NQO1, DIA4, NMOR1
Domain Architecture
Description	NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (NAD(P)H:quinone oxidoreductase 1) (QR1) (DT-diaphorase) (DTD) (Azoreductase) (Phylloquinone reductase) (Menadione reductase).

NUP53_HUMAN
θ value	5.27518 (rank : 291)	NC score	0.004589 (rank : 378)
Query Neighborhood Hits	333	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

OBSCN_HUMAN
θ value	5.27518 (rank : 292)	NC score	-0.011404 (rank : 421)
Query Neighborhood Hits	333	Target Neighborhood Hits	1931	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PALM_MOUSE
θ value	5.27518 (rank : 293)	NC score	0.004933 (rank : 376)
Query Neighborhood Hits	333	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

PHC1_HUMAN
θ value	5.27518 (rank : 294)	NC score	0.015438 (rank : 314)
Query Neighborhood Hits	333	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

RP3A_MOUSE
θ value	5.27518 (rank : 295)	NC score	0.004032 (rank : 380)
Query Neighborhood Hits	333	Target Neighborhood Hits	510	Shared Neighborhood Hits	39
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SOX10_HUMAN
θ value	5.27518 (rank : 296)	NC score	-0.000910 (rank : 406)
Query Neighborhood Hits	333	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX30_HUMAN
θ value	5.27518 (rank : 297)	NC score	0.000930 (rank : 398)
Query Neighborhood Hits	333	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

TLK2_HUMAN
θ value	5.27518 (rank : 298)	NC score	-0.011422 (rank : 422)
Query Neighborhood Hits	333	Target Neighborhood Hits	1044	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

WFDC8_HUMAN
θ value	5.27518 (rank : 299)	NC score	0.002036 (rank : 390)
Query Neighborhood Hits	333	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

YAP1_HUMAN
θ value	5.27518 (rank : 300)	NC score	0.005253 (rank : 373)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	24
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

ZFP28_HUMAN
θ value	5.27518 (rank : 301)	NC score	-0.012388 (rank : 423)
Query Neighborhood Hits	333	Target Neighborhood Hits	843	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

ZN516_MOUSE
θ value	5.27518 (rank : 302)	NC score	-0.010668 (rank : 420)
Query Neighborhood Hits	333	Target Neighborhood Hits	1197	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN750_HUMAN
θ value	5.27518 (rank : 303)	NC score	0.010151 (rank : 345)
Query Neighborhood Hits	333	Target Neighborhood Hits	183	Shared Neighborhood Hits	22
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AFF4_HUMAN
θ value	6.88961 (rank : 304)	NC score	0.008658 (rank : 350)
Query Neighborhood Hits	333	Target Neighborhood Hits	611	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CD320_HUMAN
θ value	6.88961 (rank : 305)	NC score	0.147345 (rank : 179)
Query Neighborhood Hits	333	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD5L_MOUSE
θ value	6.88961 (rank : 306)	NC score	0.076590 (rank : 244)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QWK4, O35300, O35301, Q505P6, Q91W05	Gene names	Cd5l, Aim, Api6
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (Apoptosis inhibitory 6) (Apoptosis inhibitor expressed by macrophages).

CRCM1_HUMAN
θ value	6.88961 (rank : 307)	NC score	0.001889 (rank : 391)
Query Neighborhood Hits	333	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q96D31, Q3MHV3, Q6DHX2, Q96BP7, Q96K71	Gene names	TMEM142A, CRACM1, ORAI1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

CTND2_HUMAN
θ value	6.88961 (rank : 308)	NC score	0.004830 (rank : 377)
Query Neighborhood Hits	333	Target Neighborhood Hits	333	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DACT1_MOUSE
θ value	6.88961 (rank : 309)	NC score	0.006050 (rank : 366)
Query Neighborhood Hits	333	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

ELL_HUMAN
θ value	6.88961 (rank : 310)	NC score	0.002550 (rank : 387)
Query Neighborhood Hits	333	Target Neighborhood Hits	183	Shared Neighborhood Hits	9
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

KCNH2_MOUSE
θ value	6.88961 (rank : 311)	NC score	0.000629 (rank : 401)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

LRP5_HUMAN
θ value	6.88961 (rank : 312)	NC score	0.087867 (rank : 225)
Query Neighborhood Hits	333	Target Neighborhood Hits	224	Shared Neighborhood Hits	49
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

MYCL1_HUMAN
θ value	6.88961 (rank : 313)	NC score	0.000421 (rank : 402)
Query Neighborhood Hits	333	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NCOR2_MOUSE
θ value	6.88961 (rank : 314)	NC score	0.006675 (rank : 360)
Query Neighborhood Hits	333	Target Neighborhood Hits	790	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

RTN4R_MOUSE
θ value	6.88961 (rank : 315)	NC score	-0.005237 (rank : 409)
Query Neighborhood Hits	333	Target Neighborhood Hits	293	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

SSPO_MOUSE
θ value	6.88961 (rank : 316)	NC score	0.075518 (rank : 248)
Query Neighborhood Hits	333	Target Neighborhood Hits	800	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ZNHI4_MOUSE
θ value	6.88961 (rank : 317)	NC score	0.003889 (rank : 381)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PT3, Q9CY38	Gene names	Znhit4, Hmga1l4, Papa1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

BEGIN_HUMAN
θ value	8.99809 (rank : 318)	NC score	-0.001854 (rank : 407)
Query Neighborhood Hits	333	Target Neighborhood Hits	454	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BIM_HUMAN
θ value	8.99809 (rank : 319)	NC score	0.001168 (rank : 396)
Query Neighborhood Hits	333	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

CD6_MOUSE
θ value	8.99809 (rank : 320)	NC score	0.054827 (rank : 279)
Query Neighborhood Hits	333	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

COA2_HUMAN
θ value	8.99809 (rank : 321)	NC score	0.002735 (rank : 386)
Query Neighborhood Hits	333	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

DEN1A_HUMAN
θ value	8.99809 (rank : 322)	NC score	0.005734 (rank : 368)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

EHMT2_MOUSE
θ value	8.99809 (rank : 323)	NC score	-0.005119 (rank : 408)
Query Neighborhood Hits	333	Target Neighborhood Hits	750	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FHOD1_MOUSE
θ value	8.99809 (rank : 324)	NC score	0.002090 (rank : 389)
Query Neighborhood Hits	333	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

IQEC3_MOUSE
θ value	8.99809 (rank : 325)	NC score	0.003221 (rank : 384)
Query Neighborhood Hits	333	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

LOXL3_MOUSE
θ value	8.99809 (rank : 326)	NC score	0.051937 (rank : 289)
Query Neighborhood Hits	333	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z175, Q9JJ39	Gene names	Loxl3, Lor2
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2).

LRP10_MOUSE
θ value	8.99809 (rank : 327)	NC score	0.107740 (rank : 193)
Query Neighborhood Hits	333	Target Neighborhood Hits	169	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP1B_MOUSE
θ value	8.99809 (rank : 328)	NC score	0.106748 (rank : 195)
Query Neighborhood Hits	333	Target Neighborhood Hits	606	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP4_HUMAN
θ value	8.99809 (rank : 329)	NC score	0.100972 (rank : 206)
Query Neighborhood Hits	333	Target Neighborhood Hits	355	Shared Neighborhood Hits	58
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

MUC5B_HUMAN
θ value	8.99809 (rank : 330)	NC score	0.018617 (rank : 307)
Query Neighborhood Hits	333	Target Neighborhood Hits	1020	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PDLI4_HUMAN
θ value	8.99809 (rank : 331)	NC score	0.001760 (rank : 392)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

SYNPO_MOUSE
θ value	8.99809 (rank : 332)	NC score	0.007083 (rank : 358)
Query Neighborhood Hits	333	Target Neighborhood Hits	242	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TM108_MOUSE
θ value	8.99809 (rank : 333)	NC score	0.012026 (rank : 333)
Query Neighborhood Hits	333	Target Neighborhood Hits	336	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

BMP1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.099411 (rank : 215)
Query Neighborhood Hits	333	Target Neighborhood Hits	233	Shared Neighborhood Hits	38
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.100052 (rank : 211)
Query Neighborhood Hits	333	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

C4BB_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.053788 (rank : 282)
Query Neighborhood Hits	333	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CD5L_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.073205 (rank : 256)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	O43866, Q6UX63	Gene names	CD5L
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (IgM-associated peptide).

CD6_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.057142 (rank : 273)
Query Neighborhood Hits	333	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

CO6_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.074284 (rank : 254)
Query Neighborhood Hits	333	Target Neighborhood Hits	331	Shared Neighborhood Hits	52
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8A_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.054338 (rank : 281)
Query Neighborhood Hits	333	Target Neighborhood Hits	182	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO9_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.075748 (rank : 245)
Query Neighborhood Hits	333	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.068587 (rank : 263)
Query Neighborhood Hits	333	Target Neighborhood Hits	153	Shared Neighborhood Hits	36
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CSMD1_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.079900 (rank : 237)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.080140 (rank : 235)
Query Neighborhood Hits	333	Target Neighborhood Hits	193	Shared Neighborhood Hits	24
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.079341 (rank : 240)
Query Neighborhood Hits	333	Target Neighborhood Hits	188	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.081309 (rank : 233)
Query Neighborhood Hits	333	Target Neighborhood Hits	199	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CUBN_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.078545 (rank : 243)
Query Neighborhood Hits	333	Target Neighborhood Hits	482	Shared Neighborhood Hits	50
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.084034 (rank : 230)
Query Neighborhood Hits	333	Target Neighborhood Hits	477	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.085006 (rank : 227)
Query Neighborhood Hits	333	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.080072 (rank : 236)
Query Neighborhood Hits	333	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.061666 (rank : 269)
Query Neighborhood Hits	333	Target Neighborhood Hits	110	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.084289 (rank : 228)
Query Neighborhood Hits	333	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.059137 (rank : 271)
Query Neighborhood Hits	333	Target Neighborhood Hits	118	Shared Neighborhood Hits	17
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.055989 (rank : 276)
Query Neighborhood Hits	333	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DMBT1_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.107286 (rank : 194)
Query Neighborhood Hits	333	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.113240 (rank : 191)
Query Neighborhood Hits	333	Target Neighborhood Hits	134	Shared Neighborhood Hits	39
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

EGFL7_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.053755 (rank : 283)
Query Neighborhood Hits	333	Target Neighborhood Hits	325	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.064289 (rank : 265)
Query Neighborhood Hits	333	Target Neighborhood Hits	270	Shared Neighborhood Hits	40
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.064013 (rank : 266)
Query Neighborhood Hits	333	Target Neighborhood Hits	266	Shared Neighborhood Hits	39
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

GAS6_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.079383 (rank : 239)
Query Neighborhood Hits	333	Target Neighborhood Hits	348	Shared Neighborhood Hits	47
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.075182 (rank : 249)
Query Neighborhood Hits	333	Target Neighborhood Hits	343	Shared Neighborhood Hits	42
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP126_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.055900 (rank : 277)
Query Neighborhood Hits	333	Target Neighborhood Hits	187	Shared Neighborhood Hits	18
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

IDD_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.070933 (rank : 258)
Query Neighborhood Hits	333	Target Neighborhood Hits	127	Shared Neighborhood Hits	35
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

KREM1_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.195237 (rank : 178)
Query Neighborhood Hits	333	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.199326 (rank : 176)
Query Neighborhood Hits	333	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.202285 (rank : 175)
Query Neighborhood Hits	333	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.196151 (rank : 177)
Query Neighborhood Hits	333	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LCE3B_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.052408 (rank : 286)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LG3BP_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.055124 (rank : 278)
Query Neighborhood Hits	333	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	Q08380	Gene names	LGALS3BP, M2BP
Domain Architecture
Description	Galectin-3-binding protein precursor (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K).

LOXL2_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.051983 (rank : 287)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y4K0, Q9BW70, Q9Y5Y8	Gene names	LOXL2
Domain Architecture
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14).

LOXL2_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.051051 (rank : 290)
Query Neighborhood Hits	333	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	P58022, Q8BRE6, Q8BS86, Q8C4K0, Q9JJ39	Gene names	Loxl2
Domain Architecture	No domain graphic available
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2).

LRP10_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.108074 (rank : 192)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP11_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.074188 (rank : 255)
Query Neighborhood Hits	333	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.075554 (rank : 247)
Query Neighborhood Hits	333	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.139476 (rank : 182)
Query Neighborhood Hits	333	Target Neighborhood Hits	205	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.140928 (rank : 181)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP1B_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.104563 (rank : 197)
Query Neighborhood Hits	333	Target Neighborhood Hits	602	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.100834 (rank : 208)
Query Neighborhood Hits	333	Target Neighborhood Hits	617	Shared Neighborhood Hits	69
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP3_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.141429 (rank : 180)
Query Neighborhood Hits	333	Target Neighborhood Hits	280	Shared Neighborhood Hits	55
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.099669 (rank : 214)
Query Neighborhood Hits	333	Target Neighborhood Hits	351	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.097595 (rank : 219)
Query Neighborhood Hits	333	Target Neighborhood Hits	346	Shared Neighborhood Hits	54
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.101157 (rank : 202)
Query Neighborhood Hits	333	Target Neighborhood Hits	385	Shared Neighborhood Hits	58
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LYAM2_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.056237 (rank : 275)
Query Neighborhood Hits	333	Target Neighborhood Hits	394	Shared Neighborhood Hits	34
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.053075 (rank : 284)
Query Neighborhood Hits	333	Target Neighborhood Hits	420	Shared Neighborhood Hits	40
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.052613 (rank : 285)
Query Neighborhood Hits	333	Target Neighborhood Hits	390	Shared Neighborhood Hits	38
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MFRP_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.121818 (rank : 188)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.127627 (rank : 186)
Query Neighborhood Hits	333	Target Neighborhood Hits	166	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.079453 (rank : 238)
Query Neighborhood Hits	333	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.080355 (rank : 234)
Query Neighborhood Hits	333	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.079252 (rank : 241)
Query Neighborhood Hits	333	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.078923 (rank : 242)
Query Neighborhood Hits	333	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.074722 (rank : 251)
Query Neighborhood Hits	333	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.074871 (rank : 250)
Query Neighborhood Hits	333	Target Neighborhood Hits	120	Shared Neighborhood Hits	18
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.074306 (rank : 253)
Query Neighborhood Hits	333	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.074460 (rank : 252)
Query Neighborhood Hits	333	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.090788 (rank : 223)
Query Neighborhood Hits	333	Target Neighborhood Hits	146	Shared Neighborhood Hits	24
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.092809 (rank : 222)
Query Neighborhood Hits	333	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.093906 (rank : 221)
Query Neighborhood Hits	333	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.090260 (rank : 224)
Query Neighborhood Hits	333	Target Neighborhood Hits	73	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.070951 (rank : 257)
Query Neighborhood Hits	333	Target Neighborhood Hits	74	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.070774 (rank : 259)
Query Neighborhood Hits	333	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGBM_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.056491 (rank : 274)
Query Neighborhood Hits	333	Target Neighborhood Hits	1073	Shared Neighborhood Hits	60
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PRGB_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.102848 (rank : 199)
Query Neighborhood Hits	333	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q02325	Gene names	PLGL, PRGB
Domain Architecture
Description	Plasminogen-related protein B precursor.

PROS_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.082189 (rank : 231)
Query Neighborhood Hits	333	Target Neighborhood Hits	340	Shared Neighborhood Hits	43
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.075668 (rank : 246)
Query Neighborhood Hits	333	Target Neighborhood Hits	330	Shared Neighborhood Hits	40
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PRS23_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.129448 (rank : 185)
Query Neighborhood Hits	333	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D6X6, Q544M8, Q8VEG1	Gene names	Prss23
Domain Architecture
Description	Serine protease 23 precursor (EC 3.4.21.-).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.081542 (rank : 232)
Query Neighborhood Hits	333	Target Neighborhood Hits	289	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SPIT1_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.063734 (rank : 267)
Query Neighborhood Hits	333	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT1_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.061939 (rank : 268)
Query Neighborhood Hits	333	Target Neighborhood Hits	96	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

TLL1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.100925 (rank : 207)
Query Neighborhood Hits	333	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.100072 (rank : 210)
Query Neighborhood Hits	333	Target Neighborhood Hits	237	Shared Neighborhood Hits	38
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.101144 (rank : 203)
Query Neighborhood Hits	333	Target Neighborhood Hits	241	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.101173 (rank : 201)
Query Neighborhood Hits	333	Target Neighborhood Hits	240	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TMG1_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.136215 (rank : 183)
Query Neighborhood Hits	333	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TMG2_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.104514 (rank : 198)
Query Neighborhood Hits	333	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

TMG2_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.099289 (rank : 216)
Query Neighborhood Hits	333	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

TMG3_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.123224 (rank : 187)
Query Neighborhood Hits	333	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG3_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.121115 (rank : 189)
Query Neighborhood Hits	333	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG4_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.105704 (rank : 196)
Query Neighborhood Hits	333	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMG4_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.100708 (rank : 209)
Query Neighborhood Hits	333	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TSG6_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.070241 (rank : 261)
Query Neighborhood Hits	333	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.068973 (rank : 262)
Query Neighborhood Hits	333	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

VLDLR_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.101046 (rank : 204)
Query Neighborhood Hits	333	Target Neighborhood Hits	383	Shared Neighborhood Hits	55
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.102791 (rank : 200)
Query Neighborhood Hits	333	Target Neighborhood Hits	360	Shared Neighborhood Hits	55
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

Hits sorted by NC score

TMPSD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	333	Target Neighborhood Hits	333	Shared Neighborhood Hits	333
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
NC score	0.995338 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	333	Target Neighborhood Hits	334	Shared Neighborhood Hits	241
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPS4_MOUSE
NC score	0.987597 (rank : 3)	θ value	2.4834e-66 (rank : 9)
Query Neighborhood Hits	333	Target Neighborhood Hits	210	Shared Neighborhood Hits	189
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS4_HUMAN
NC score	0.987496 (rank : 4)	θ value	2.3998e-69 (rank : 7)
Query Neighborhood Hits	333	Target Neighborhood Hits	203	Shared Neighborhood Hits	186
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS5_MOUSE
NC score	0.987392 (rank : 5)	θ value	8.53533e-67 (rank : 8)
Query Neighborhood Hits	333	Target Neighborhood Hits	185	Shared Neighborhood Hits	179
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_HUMAN
NC score	0.987112 (rank : 6)	θ value	1.50663e-63 (rank : 10)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	178
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS3_MOUSE
NC score	0.986545 (rank : 7)	θ value	4.99229e-75 (rank : 4)
Query Neighborhood Hits	333	Target Neighborhood Hits	239	Shared Neighborhood Hits	199
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS2_HUMAN
NC score	0.986430 (rank : 8)	θ value	9.41505e-74 (rank : 5)
Query Neighborhood Hits	333	Target Neighborhood Hits	252	Shared Neighborhood Hits	192
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

HEPS_HUMAN
NC score	0.986084 (rank : 9)	θ value	9.1404e-61 (rank : 11)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
NC score	0.985937 (rank : 10)	θ value	2.65945e-60 (rank : 12)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	176
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

TMPS2_MOUSE
NC score	0.985812 (rank : 11)	θ value	2.64714e-76 (rank : 3)
Query Neighborhood Hits	333	Target Neighborhood Hits	243	Shared Neighborhood Hits	192
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
NC score	0.985769 (rank : 12)	θ value	1.35953e-72 (rank : 6)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	200
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TEST_MOUSE
NC score	0.984813 (rank : 13)	θ value	4.70527e-49 (rank : 31)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

TEST_HUMAN
NC score	0.984509 (rank : 14)	θ value	2.49495e-50 (rank : 29)
Query Neighborhood Hits	333	Target Neighborhood Hits	172	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

PRSS8_MOUSE
NC score	0.984454 (rank : 15)	θ value	8.87376e-48 (rank : 36)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

TRYG1_MOUSE
NC score	0.984377 (rank : 16)	θ value	4.86918e-46 (rank : 47)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	175
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

PRSS8_HUMAN
NC score	0.984204 (rank : 17)	θ value	2.49495e-50 (rank : 28)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

TMSP8_MOUSE
NC score	0.984170 (rank : 18)	θ value	3.26607e-42 (rank : 56)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	175
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TRYG1_HUMAN
NC score	0.984050 (rank : 19)	θ value	1.15895e-47 (rank : 37)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

PRS27_MOUSE
NC score	0.983933 (rank : 20)	θ value	1.28137e-46 (rank : 42)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRS27_HUMAN
NC score	0.983888 (rank : 21)	θ value	9.81109e-47 (rank : 41)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

ACRO_MOUSE
NC score	0.983476 (rank : 22)	θ value	1.19932e-44 (rank : 51)
Query Neighborhood Hits	333	Target Neighborhood Hits	185	Shared Neighborhood Hits	174
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TM11D_HUMAN
NC score	0.983236 (rank : 23)	θ value	1.28137e-46 (rank : 43)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	175
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

DESC4_MOUSE
NC score	0.982764 (rank : 24)	θ value	6.35935e-46 (rank : 48)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	173
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

BSSP4_HUMAN
NC score	0.982406 (rank : 25)	θ value	1.3722e-40 (rank : 57)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

ACRO_HUMAN
NC score	0.982258 (rank : 26)	θ value	1.73182e-43 (rank : 54)
Query Neighborhood Hits	333	Target Neighborhood Hits	291	Shared Neighborhood Hits	189
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TM11E_HUMAN
NC score	0.981809 (rank : 27)	θ value	5.02714e-51 (rank : 25)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
NC score	0.981784 (rank : 28)	θ value	1.01294e-51 (rank : 23)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	173
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

BSSP4_MOUSE
NC score	0.981671 (rank : 29)	θ value	1.08726e-37 (rank : 61)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TM11D_MOUSE
NC score	0.981416 (rank : 30)	θ value	3.26607e-42 (rank : 55)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	175
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

KLKB1_MOUSE
NC score	0.980187 (rank : 31)	θ value	2.57589e-55 (rank : 16)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_HUMAN
NC score	0.980081 (rank : 32)	θ value	6.77864e-56 (rank : 13)
Query Neighborhood Hits	333	Target Neighborhood Hits	183	Shared Neighborhood Hits	174
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

MCPT6_MOUSE
NC score	0.979744 (rank : 33)	θ value	5.20228e-48 (rank : 34)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

TRYB1_MOUSE
NC score	0.979730 (rank : 34)	θ value	3.72821e-46 (rank : 46)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

FA11_MOUSE
NC score	0.979372 (rank : 35)	θ value	5.93839e-52 (rank : 22)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	174
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_HUMAN
NC score	0.978895 (rank : 36)	θ value	2.94719e-51 (rank : 24)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	174
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

CTRB1_HUMAN
NC score	0.978277 (rank : 37)	θ value	4.13158e-37 (rank : 65)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	175
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
NC score	0.978098 (rank : 38)	θ value	7.29293e-34 (rank : 80)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	175
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

POLS2_MOUSE
NC score	0.977895 (rank : 39)	θ value	3.1488e-53 (rank : 20)
Query Neighborhood Hits	333	Target Neighborhood Hits	188	Shared Neighborhood Hits	174
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TRYB1_HUMAN
NC score	0.977374 (rank : 40)	θ value	8.30557e-46 (rank : 49)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.977374 (rank : 41)	θ value	8.30557e-46 (rank : 50)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

POLS2_HUMAN
NC score	0.977292 (rank : 42)	θ value	3.98324e-48 (rank : 33)
Query Neighborhood Hits	333	Target Neighborhood Hits	192	Shared Neighborhood Hits	176
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TRYA1_HUMAN
NC score	0.976967 (rank : 43)	θ value	1.01529e-43 (rank : 53)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	176
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TSP50_HUMAN
NC score	0.975569 (rank : 44)	θ value	2.19584e-30 (rank : 100)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

ELA2A_MOUSE
NC score	0.973816 (rank : 45)	θ value	9.20422e-37 (rank : 66)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

TMPS9_MOUSE
NC score	0.971785 (rank : 46)	θ value	1.28137e-46 (rank : 44)
Query Neighborhood Hits	333	Target Neighborhood Hits	296	Shared Neighborhood Hits	197
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

ELA2A_HUMAN
NC score	0.971773 (rank : 47)	θ value	3.16345e-37 (rank : 64)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	175
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

TMPS9_HUMAN
NC score	0.971748 (rank : 48)	θ value	5.20228e-48 (rank : 35)
Query Neighborhood Hits	333	Target Neighborhood Hits	276	Shared Neighborhood Hits	193
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

CLCR_HUMAN
NC score	0.970827 (rank : 49)	θ value	3.3877e-31 (rank : 92)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

ELA2B_HUMAN
NC score	0.969968 (rank : 50)	θ value	8.06329e-33 (rank : 87)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA1_HUMAN
NC score	0.968529 (rank : 51)	θ value	2.05049e-36 (rank : 68)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

TRYD_HUMAN
NC score	0.968250 (rank : 52)	θ value	2.19584e-30 (rank : 99)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRY2_MOUSE
NC score	0.966871 (rank : 53)	θ value	2.26708e-35 (rank : 72)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY2_HUMAN
NC score	0.965046 (rank : 54)	θ value	5.22648e-32 (rank : 90)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	173
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY1_HUMAN
NC score	0.964294 (rank : 55)	θ value	1.24399e-33 (rank : 83)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

CFAD_MOUSE
NC score	0.964024 (rank : 56)	θ value	1.02001e-27 (rank : 117)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

TRY3_HUMAN
NC score	0.963996 (rank : 57)	θ value	6.17384e-33 (rank : 86)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	175
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

ELA3A_HUMAN
NC score	0.962224 (rank : 58)	θ value	3.28125e-26 (rank : 129)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	173
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
NC score	0.961462 (rank : 59)	θ value	5.59698e-26 (rank : 130)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	173
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

GRAM_HUMAN
NC score	0.961144 (rank : 60)	θ value	7.56453e-23 (rank : 140)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

KLK6_HUMAN
NC score	0.960848 (rank : 61)	θ value	5.77852e-31 (rank : 95)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

GRAK_MOUSE
NC score	0.960412 (rank : 62)	θ value	3.17079e-29 (rank : 107)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	173
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

UROK_MOUSE
NC score	0.960405 (rank : 63)	θ value	8.61488e-35 (rank : 73)
Query Neighborhood Hits	333	Target Neighborhood Hits	273	Shared Neighborhood Hits	175
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

KLK13_HUMAN
NC score	0.960142 (rank : 64)	θ value	1.6247e-33 (rank : 84)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

CFAD_HUMAN
NC score	0.959589 (rank : 65)	θ value	2.27234e-27 (rank : 123)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

UROK_HUMAN
NC score	0.959420 (rank : 66)	θ value	8.32485e-38 (rank : 60)
Query Neighborhood Hits	333	Target Neighborhood Hits	272	Shared Neighborhood Hits	175
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

KLK7_MOUSE
NC score	0.956461 (rank : 67)	θ value	1.4233e-29 (rank : 105)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK14_HUMAN
NC score	0.955875 (rank : 68)	θ value	8.63488e-27 (rank : 126)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK7_HUMAN
NC score	0.955297 (rank : 69)	θ value	2.05525e-28 (rank : 114)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK12_HUMAN
NC score	0.954945 (rank : 70)	θ value	7.80994e-28 (rank : 115)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

PLMN_HUMAN
NC score	0.954093 (rank : 71)	θ value	1.67352e-46 (rank : 45)
Query Neighborhood Hits	333	Target Neighborhood Hits	204	Shared Neighborhood Hits	175
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
NC score	0.953310 (rank : 72)	θ value	3.37202e-47 (rank : 39)
Query Neighborhood Hits	333	Target Neighborhood Hits	208	Shared Neighborhood Hits	176
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

KLK15_HUMAN
NC score	0.953248 (rank : 73)	θ value	9.54697e-26 (rank : 132)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	174
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

NRPN_HUMAN
NC score	0.953246 (rank : 74)	θ value	7.80994e-28 (rank : 116)
Query Neighborhood Hits	333	Target Neighborhood Hits	182	Shared Neighborhood Hits	174
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

TMPS6_MOUSE
NC score	0.952500 (rank : 75)	θ value	1.97229e-55 (rank : 14)
Query Neighborhood Hits	333	Target Neighborhood Hits	341	Shared Neighborhood Hits	190
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

KLK11_HUMAN
NC score	0.952407 (rank : 76)	θ value	9.8567e-31 (rank : 97)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK5_HUMAN
NC score	0.951791 (rank : 77)	θ value	1.05554e-24 (rank : 135)
Query Neighborhood Hits	333	Target Neighborhood Hits	182	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK11_MOUSE
NC score	0.951331 (rank : 78)	θ value	3.17079e-29 (rank : 108)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK4_HUMAN
NC score	0.950985 (rank : 79)	θ value	1.2077e-20 (rank : 145)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK10_HUMAN
NC score	0.950596 (rank : 80)	θ value	4.01107e-24 (rank : 138)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	174
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK9_HUMAN
NC score	0.950223 (rank : 81)	θ value	4.73814e-25 (rank : 134)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

NRPN_MOUSE
NC score	0.949213 (rank : 82)	θ value	1.57365e-28 (rank : 113)
Query Neighborhood Hits	333	Target Neighborhood Hits	186	Shared Neighborhood Hits	174
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

TMPS6_HUMAN
NC score	0.948342 (rank : 83)	θ value	4.85792e-54 (rank : 19)
Query Neighborhood Hits	333	Target Neighborhood Hits	338	Shared Neighborhood Hits	190
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_MOUSE
NC score	0.947710 (rank : 84)	θ value	1.97229e-55 (rank : 15)
Query Neighborhood Hits	333	Target Neighborhood Hits	275	Shared Neighborhood Hits	189
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_HUMAN
NC score	0.946909 (rank : 85)	θ value	1.66964e-54 (rank : 18)
Query Neighborhood Hits	333	Target Neighborhood Hits	275	Shared Neighborhood Hits	189
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

KLK2_HUMAN
NC score	0.946072 (rank : 86)	θ value	5.06226e-27 (rank : 124)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

CFAI_MOUSE
NC score	0.946042 (rank : 87)	θ value	1.46948e-34 (rank : 75)
Query Neighborhood Hits	333	Target Neighborhood Hits	290	Shared Neighborhood Hits	199
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

THRB_MOUSE
NC score	0.944907 (rank : 88)	θ value	9.8567e-31 (rank : 98)
Query Neighborhood Hits	333	Target Neighborhood Hits	195	Shared Neighborhood Hits	174
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

APOA_HUMAN
NC score	0.944850 (rank : 89)	θ value	4.55743e-44 (rank : 52)
Query Neighborhood Hits	333	Target Neighborhood Hits	221	Shared Neighborhood Hits	177
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

THRB_HUMAN
NC score	0.944106 (rank : 90)	θ value	7.54701e-31 (rank : 96)
Query Neighborhood Hits	333	Target Neighborhood Hits	196	Shared Neighborhood Hits	174
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TPA_MOUSE
NC score	0.943041 (rank : 91)	θ value	3.73686e-38 (rank : 59)
Query Neighborhood Hits	333	Target Neighborhood Hits	335	Shared Neighborhood Hits	180
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

K1KB9_MOUSE
NC score	0.942993 (rank : 92)	θ value	1.73584e-35 (rank : 71)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

CFAI_HUMAN
NC score	0.942763 (rank : 93)	θ value	9.2256e-29 (rank : 110)
Query Neighborhood Hits	333	Target Neighborhood Hits	289	Shared Neighborhood Hits	199
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

KLK3_HUMAN
NC score	0.942741 (rank : 94)	θ value	2.51237e-26 (rank : 128)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	175
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

TPA_HUMAN
NC score	0.942734 (rank : 95)	θ value	1.20211e-36 (rank : 67)
Query Neighborhood Hits	333	Target Neighborhood Hits	324	Shared Neighborhood Hits	178
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

K1B11_MOUSE
NC score	0.942058 (rank : 96)	θ value	4.27553e-34 (rank : 78)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	174
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1KB1_MOUSE
NC score	0.941861 (rank : 97)	θ value	5.584e-34 (rank : 79)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	175
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

ENTK_HUMAN
NC score	0.941394 (rank : 98)	θ value	5.73848e-55 (rank : 17)
Query Neighborhood Hits	333	Target Neighborhood Hits	310	Shared Neighborhood Hits	199
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

K1KB3_MOUSE
NC score	0.940974 (rank : 99)	θ value	7.29293e-34 (rank : 81)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

KLK1_MOUSE
NC score	0.940543 (rank : 100)	θ value	1.79631e-32 (rank : 89)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	174
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

K1B24_MOUSE
NC score	0.938346 (rank : 101)	θ value	8.3442e-30 (rank : 103)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	174
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B22_MOUSE
NC score	0.938260 (rank : 102)	θ value	4.42448e-31 (rank : 93)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B27_MOUSE
NC score	0.937534 (rank : 103)	θ value	1.57365e-28 (rank : 112)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1B21_MOUSE
NC score	0.936376 (rank : 104)	θ value	1.08979e-29 (rank : 104)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	175
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

K1KB5_MOUSE
NC score	0.936100 (rank : 105)	θ value	1.16434e-31 (rank : 91)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	175
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

KLK1_HUMAN
NC score	0.935299 (rank : 106)	θ value	1.33217e-27 (rank : 120)
Query Neighborhood Hits	333	Target Neighborhood Hits	183	Shared Neighborhood Hits	174
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

K1B26_MOUSE
NC score	0.934152 (rank : 107)	θ value	4.89182e-30 (rank : 102)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

EGFB2_MOUSE
NC score	0.933497 (rank : 108)	θ value	1.2049e-28 (rank : 111)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	174
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

K1KB8_MOUSE
NC score	0.932657 (rank : 109)	θ value	5.40856e-29 (rank : 109)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

ENTK_MOUSE
NC score	0.931047 (rank : 110)	θ value	2.49495e-50 (rank : 27)
Query Neighborhood Hits	333	Target Neighborhood Hits	338	Shared Neighborhood Hits	200
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CATG_MOUSE
NC score	0.930616 (rank : 111)	θ value	1.47631e-18 (rank : 152)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

K1KB4_MOUSE
NC score	0.929897 (rank : 112)	θ value	2.42779e-29 (rank : 106)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

MCPT2_MOUSE
NC score	0.926045 (rank : 113)	θ value	1.5773e-20 (rank : 146)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

PRTN3_HUMAN
NC score	0.924613 (rank : 114)	θ value	8.65492e-19 (rank : 151)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	172
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

CATG_HUMAN
NC score	0.924294 (rank : 115)	θ value	4.74913e-17 (rank : 155)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

MCPT1_MOUSE
NC score	0.923452 (rank : 116)	θ value	5.99374e-20 (rank : 147)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

CAP7_HUMAN
NC score	0.923035 (rank : 117)	θ value	6.41864e-14 (rank : 166)
Query Neighborhood Hits	333	Target Neighborhood Hits	169	Shared Neighborhood Hits	169
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

HGFL_MOUSE
NC score	0.922372 (rank : 118)	θ value	2.35151e-24 (rank : 137)
Query Neighborhood Hits	333	Target Neighborhood Hits	188	Shared Neighborhood Hits	172
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

GRAH_HUMAN
NC score	0.922070 (rank : 119)	θ value	9.90251e-15 (rank : 162)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

MCPT4_MOUSE
NC score	0.921447 (rank : 120)	θ value	2.27762e-19 (rank : 149)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

HGFL_HUMAN
NC score	0.921330 (rank : 121)	θ value	1.6852e-22 (rank : 142)
Query Neighborhood Hits	333	Target Neighborhood Hits	190	Shared Neighborhood Hits	173
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

PRTN3_MOUSE
NC score	0.920116 (rank : 122)	θ value	2.13179e-17 (rank : 154)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	174
SwissProt Accessions	Q61096, O08809	Gene names	Prtn3
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Proteinase 3) (PR-3).

FA7_MOUSE
NC score	0.919307 (rank : 123)	θ value	1.24399e-33 (rank : 82)
Query Neighborhood Hits	333	Target Neighborhood Hits	374	Shared Neighborhood Hits	183
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

PROC_HUMAN
NC score	0.919188 (rank : 124)	θ value	3.61944e-33 (rank : 85)
Query Neighborhood Hits	333	Target Neighborhood Hits	406	Shared Neighborhood Hits	185
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

GRAF_MOUSE
NC score	0.919167 (rank : 125)	θ value	1.99067e-23 (rank : 139)
Query Neighborhood Hits	333	Target Neighborhood Hits	172	Shared Neighborhood Hits	172
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

K1B16_MOUSE
NC score	0.916725 (rank : 126)	θ value	4.9032e-22 (rank : 143)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	174
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

FA12_HUMAN
NC score	0.916480 (rank : 127)	θ value	1.85459e-37 (rank : 62)
Query Neighborhood Hits	333	Target Neighborhood Hits	425	Shared Neighborhood Hits	181
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

HGF_MOUSE
NC score	0.916008 (rank : 128)	θ value	1.02001e-27 (rank : 118)
Query Neighborhood Hits	333	Target Neighborhood Hits	192	Shared Neighborhood Hits	171
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_HUMAN
NC score	0.915989 (rank : 129)	θ value	3.62785e-25 (rank : 133)
Query Neighborhood Hits	333	Target Neighborhood Hits	191	Shared Neighborhood Hits	171
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

GRAC_MOUSE
NC score	0.914989 (rank : 130)	θ value	8.10077e-17 (rank : 156)
Query Neighborhood Hits	333	Target Neighborhood Hits	177	Shared Neighborhood Hits	173
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

MCPTX_MOUSE
NC score	0.912963 (rank : 131)	θ value	1.16975e-15 (rank : 160)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q00356	Gene names	Mcptl
Domain Architecture
Description	Mast cell protease-like protein precursor (EC 3.4.21.-).

GRAG_MOUSE
NC score	0.912461 (rank : 132)	θ value	7.82807e-20 (rank : 148)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	172
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

MCPT9_MOUSE
NC score	0.912418 (rank : 133)	θ value	1.058e-16 (rank : 157)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

MCPT1_HUMAN
NC score	0.910069 (rank : 134)	θ value	8.95645e-16 (rank : 159)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	173
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

HPT_MOUSE
NC score	0.909840 (rank : 135)	θ value	2.88119e-14 (rank : 165)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	169
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HGFA_MOUSE
NC score	0.909236 (rank : 136)	θ value	1.85459e-37 (rank : 63)
Query Neighborhood Hits	333	Target Neighborhood Hits	419	Shared Neighborhood Hits	179
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_HUMAN
NC score	0.908284 (rank : 137)	θ value	9.83387e-39 (rank : 58)
Query Neighborhood Hits	333	Target Neighborhood Hits	436	Shared Neighborhood Hits	184
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ELNE_MOUSE
NC score	0.908240 (rank : 138)	θ value	1.29331e-14 (rank : 163)
Query Neighborhood Hits	333	Target Neighborhood Hits	167	Shared Neighborhood Hits	163
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

GRAE_MOUSE
NC score	0.907480 (rank : 139)	θ value	1.47631e-18 (rank : 153)
Query Neighborhood Hits	333	Target Neighborhood Hits	172	Shared Neighborhood Hits	171
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

FA7_HUMAN
NC score	0.907178 (rank : 140)	θ value	5.77852e-31 (rank : 94)
Query Neighborhood Hits	333	Target Neighborhood Hits	404	Shared Neighborhood Hits	184
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

ELNE_HUMAN
NC score	0.907016 (rank : 141)	θ value	2.0648e-12 (rank : 169)
Query Neighborhood Hits	333	Target Neighborhood Hits	164	Shared Neighborhood Hits	163
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

GRAD_MOUSE
NC score	0.906731 (rank : 142)	θ value	8.65492e-19 (rank : 150)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	171
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

PROC_MOUSE
NC score	0.906145 (rank : 143)	θ value	1.32909e-35 (rank : 70)
Query Neighborhood Hits	333	Target Neighborhood Hits	426	Shared Neighborhood Hits	187
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MCPT8_MOUSE
NC score	0.903977 (rank : 144)	θ value	1.68911e-14 (rank : 164)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

NETR_MOUSE
NC score	0.903735 (rank : 145)	θ value	5.7518e-47 (rank : 40)
Query Neighborhood Hits	333	Target Neighborhood Hits	216	Shared Neighborhood Hits	185
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

FA9_HUMAN
NC score	0.903091 (rank : 146)	θ value	8.06329e-33 (rank : 88)
Query Neighborhood Hits	333	Target Neighborhood Hits	421	Shared Neighborhood Hits	183
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

HPTR_HUMAN
NC score	0.900646 (rank : 147)	θ value	4.44505e-15 (rank : 161)
Query Neighborhood Hits	333	Target Neighborhood Hits	166	Shared Neighborhood Hits	164
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
NC score	0.899870 (rank : 148)	θ value	6.85773e-16 (rank : 158)
Query Neighborhood Hits	333	Target Neighborhood Hits	184	Shared Neighborhood Hits	164
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

NETR_HUMAN
NC score	0.898603 (rank : 149)	θ value	2.3352e-48 (rank : 32)
Query Neighborhood Hits	333	Target Neighborhood Hits	218	Shared Neighborhood Hits	186
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

MCPT5_MOUSE
NC score	0.892570 (rank : 150)	θ value	9.59137e-10 (rank : 172)
Query Neighborhood Hits	333	Target Neighborhood Hits	175	Shared Neighborhood Hits	174
SwissProt Accessions	P21844, Q9R1F0	Gene names	Mcpt5
Domain Architecture
Description	Mast cell protease 5 precursor (EC 3.4.21.-) (MMCP-5) (Mast cell chymase 1).

FA10_HUMAN
NC score	0.891638 (rank : 151)	θ value	1.12514e-34 (rank : 74)
Query Neighborhood Hits	333	Target Neighborhood Hits	431	Shared Neighborhood Hits	186
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
NC score	0.888517 (rank : 152)	θ value	4.568e-36 (rank : 69)
Query Neighborhood Hits	333	Target Neighborhood Hits	435	Shared Neighborhood Hits	186
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

ST14_MOUSE
NC score	0.884879 (rank : 153)	θ value	1.91031e-50 (rank : 26)
Query Neighborhood Hits	333	Target Neighborhood Hits	419	Shared Neighborhood Hits	191
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ST14_HUMAN
NC score	0.883659 (rank : 154)	θ value	1.97686e-47 (rank : 38)
Query Neighborhood Hits	333	Target Neighborhood Hits	409	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

HABP2_HUMAN
NC score	0.879582 (rank : 155)	θ value	3.27365e-34 (rank : 77)
Query Neighborhood Hits	333	Target Neighborhood Hits	431	Shared Neighborhood Hits	177
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
NC score	0.877990 (rank : 156)	θ value	1.9192e-34 (rank : 76)
Query Neighborhood Hits	333	Target Neighborhood Hits	445	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MASP1_MOUSE
NC score	0.868961 (rank : 157)	θ value	1.12775e-26 (rank : 127)
Query Neighborhood Hits	333	Target Neighborhood Hits	364	Shared Neighborhood Hits	182
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

CORIN_MOUSE
NC score	0.866458 (rank : 158)	θ value	2.041e-52 (rank : 21)
Query Neighborhood Hits	333	Target Neighborhood Hits	451	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

MASP1_HUMAN
NC score	0.864490 (rank : 159)	θ value	1.73987e-27 (rank : 121)
Query Neighborhood Hits	333	Target Neighborhood Hits	369	Shared Neighborhood Hits	182
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

CORIN_HUMAN
NC score	0.862546 (rank : 160)	θ value	4.25575e-50 (rank : 30)
Query Neighborhood Hits	333	Target Neighborhood Hits	453	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MASP2_MOUSE
NC score	0.857806 (rank : 161)	θ value	1.02001e-27 (rank : 119)
Query Neighborhood Hits	333	Target Neighborhood Hits	382	Shared Neighborhood Hits	182
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_HUMAN
NC score	0.856694 (rank : 162)	θ value	3.74554e-30 (rank : 101)
Query Neighborhood Hits	333	Target Neighborhood Hits	364	Shared Neighborhood Hits	183
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CS1B_MOUSE
NC score	0.847054 (rank : 163)	θ value	1.29031e-22 (rank : 141)
Query Neighborhood Hits	333	Target Neighborhood Hits	361	Shared Neighborhood Hits	181
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CS1A_MOUSE
NC score	0.842877 (rank : 164)	θ value	4.15078e-21 (rank : 144)
Query Neighborhood Hits	333	Target Neighborhood Hits	360	Shared Neighborhood Hits	180
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

C1S_HUMAN
NC score	0.842301 (rank : 165)	θ value	1.80048e-24 (rank : 136)
Query Neighborhood Hits	333	Target Neighborhood Hits	359	Shared Neighborhood Hits	180
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

C1RB_MOUSE
NC score	0.836562 (rank : 166)	θ value	8.63488e-27 (rank : 125)
Query Neighborhood Hits	333	Target Neighborhood Hits	380	Shared Neighborhood Hits	184
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
NC score	0.835587 (rank : 167)	θ value	7.30988e-26 (rank : 131)
Query Neighborhood Hits	333	Target Neighborhood Hits	364	Shared Neighborhood Hits	180
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1RA_MOUSE
NC score	0.831690 (rank : 168)	θ value	2.27234e-27 (rank : 122)
Query Neighborhood Hits	333	Target Neighborhood Hits	379	Shared Neighborhood Hits	184
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

CO2_MOUSE
NC score	0.784707 (rank : 169)	θ value	7.09661e-13 (rank : 168)
Query Neighborhood Hits	333	Target Neighborhood Hits	250	Shared Neighborhood Hits	170
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_HUMAN
NC score	0.745014 (rank : 170)	θ value	1.74796e-11 (rank : 171)
Query Neighborhood Hits	333	Target Neighborhood Hits	258	Shared Neighborhood Hits	173
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CFAB_HUMAN
NC score	0.743869 (rank : 171)	θ value	1.33837e-11 (rank : 170)
Query Neighborhood Hits	333	Target Neighborhood Hits	251	Shared Neighborhood Hits	168
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
NC score	0.733582 (rank : 172)	θ value	8.38298e-14 (rank : 167)
Query Neighborhood Hits	333	Target Neighborhood Hits	262	Shared Neighborhood Hits	168
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

PROZ_HUMAN
NC score	0.553465 (rank : 173)	θ value	0.000786445 (rank : 177)
Query Neighborhood Hits	333	Target Neighborhood Hits	422	Shared Neighborhood Hits	173
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
NC score	0.523183 (rank : 174)	θ value	0.000602161 (rank : 176)
Query Neighborhood Hits	333	Target Neighborhood Hits	410	Shared Neighborhood Hits	169
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

KREM2_HUMAN
NC score	0.202285 (rank : 175)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	333	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM1_MOUSE
NC score	0.199326 (rank : 176)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	333	Target Neighborhood Hits	92	Shared Neighborhood Hits	35
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_MOUSE
NC score	0.196151 (rank : 177)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	333	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM1_HUMAN
NC score	0.195237 (rank : 178)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	333	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

CD320_HUMAN
NC score	0.147345 (rank : 179)	θ value	6.88961 (rank : 305)
Query Neighborhood Hits	333	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

LRP3_HUMAN
NC score	0.141429 (rank : 180)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	333	Target Neighborhood Hits	280	Shared Neighborhood Hits	55
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP12_MOUSE
NC score	0.140928 (rank : 181)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.139476 (rank : 182)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	333	Target Neighborhood Hits	205	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

TMG1_HUMAN
NC score	0.136215 (rank : 183)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	333	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

PRS23_HUMAN
NC score	0.129752 (rank : 184)	θ value	0.813845 (rank : 219)
Query Neighborhood Hits	333	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	O95084	Gene names	PRSS23, ZSIG13
Domain Architecture
Description	Serine protease 23 precursor (EC 3.4.21.-) (Putative secreted protein ZSIG13).

PRS23_MOUSE
NC score	0.129448 (rank : 185)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	333	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D6X6, Q544M8, Q8VEG1	Gene names	Prss23
Domain Architecture
Description	Serine protease 23 precursor (EC 3.4.21.-).

MFRP_MOUSE
NC score	0.127627 (rank : 186)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	333	Target Neighborhood Hits	166	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TMG3_HUMAN
NC score	0.123224 (rank : 187)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	333	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

MFRP_HUMAN
NC score	0.121818 (rank : 188)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TMG3_MOUSE
NC score	0.121115 (rank : 189)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	333	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

LRP2_HUMAN
NC score	0.115395 (rank : 190)	θ value	3.0926 (rank : 257)
Query Neighborhood Hits	333	Target Neighborhood Hits	573	Shared Neighborhood Hits	71
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

DMBT1_MOUSE
NC score	0.113240 (rank : 191)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	333	Target Neighborhood Hits	134	Shared Neighborhood Hits	39
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

LRP10_HUMAN
NC score	0.108074 (rank : 192)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
NC score	0.107740 (rank : 193)	θ value	8.99809 (rank : 327)
Query Neighborhood Hits	333	Target Neighborhood Hits	169	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

DMBT1_HUMAN
NC score	0.107286 (rank : 194)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	333	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

LRP1B_MOUSE
NC score	0.106748 (rank : 195)	θ value	8.99809 (rank : 328)
Query Neighborhood Hits	333	Target Neighborhood Hits	606	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TMG4_HUMAN
NC score	0.105704 (rank : 196)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	333	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

LRP1B_HUMAN
NC score	0.104563 (rank : 197)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	333	Target Neighborhood Hits	602	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TMG2_HUMAN
NC score	0.104514 (rank : 198)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	333	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

PRGB_HUMAN
NC score	0.102848 (rank : 199)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	333	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q02325	Gene names	PLGL, PRGB
Domain Architecture
Description	Plasminogen-related protein B precursor.

VLDLR_MOUSE
NC score	0.102791 (rank : 200)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	333	Target Neighborhood Hits	360	Shared Neighborhood Hits	55
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TLL2_MOUSE
NC score	0.101173 (rank : 201)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	333	Target Neighborhood Hits	240	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

LRP8_MOUSE
NC score	0.101157 (rank : 202)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	333	Target Neighborhood Hits	385	Shared Neighborhood Hits	58
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TLL2_HUMAN
NC score	0.101144 (rank : 203)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	333	Target Neighborhood Hits	241	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

VLDLR_HUMAN
NC score	0.101046 (rank : 204)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	333	Target Neighborhood Hits	383	Shared Neighborhood Hits	55
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LDLR_MOUSE
NC score	0.101043 (rank : 205)	θ value	1.81305 (rank : 238)
Query Neighborhood Hits	333	Target Neighborhood Hits	382	Shared Neighborhood Hits	56
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP4_HUMAN
NC score	0.100972 (rank : 206)	θ value	8.99809 (rank : 329)
Query Neighborhood Hits	333	Target Neighborhood Hits	355	Shared Neighborhood Hits	58
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

TLL1_HUMAN
NC score	0.100925 (rank : 207)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	333	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

LRP1_HUMAN
NC score	0.100834 (rank : 208)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	333	Target Neighborhood Hits	617	Shared Neighborhood Hits	69
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

TMG4_MOUSE
NC score	0.100708 (rank : 209)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	333	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TLL1_MOUSE
NC score	0.100072 (rank : 210)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	333	Target Neighborhood Hits	237	Shared Neighborhood Hits	38
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_MOUSE
NC score	0.100052 (rank : 211)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	333	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

LDLR_HUMAN
NC score	0.099850 (rank : 212)	θ value	2.36792 (rank : 248)
Query Neighborhood Hits	333	Target Neighborhood Hits	375	Shared Neighborhood Hits	58
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP6_HUMAN
NC score	0.099761 (rank : 213)	θ value	2.36792 (rank : 249)
Query Neighborhood Hits	333	Target Neighborhood Hits	235	Shared Neighborhood Hits	54
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP4_MOUSE
NC score	0.099669 (rank : 214)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	333	Target Neighborhood Hits	351	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

BMP1_HUMAN
NC score	0.099411 (rank : 215)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	333	Target Neighborhood Hits	233	Shared Neighborhood Hits	38
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TMG2_MOUSE
NC score	0.099289 (rank : 216)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	333	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

LRP6_MOUSE
NC score	0.099198 (rank : 217)	θ value	2.36792 (rank : 250)
Query Neighborhood Hits	333	Target Neighborhood Hits	232	Shared Neighborhood Hits	53
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

SORL_MOUSE
NC score	0.098827 (rank : 218)	θ value	1.06291 (rank : 225)
Query Neighborhood Hits	333	Target Neighborhood Hits	439	Shared Neighborhood Hits	42
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LRP8_HUMAN
NC score	0.097595 (rank : 219)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	333	Target Neighborhood Hits	346	Shared Neighborhood Hits	54
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SORL_HUMAN
NC score	0.095376 (rank : 220)	θ value	1.06291 (rank : 224)
Query Neighborhood Hits	333	Target Neighborhood Hits	440	Shared Neighborhood Hits	40
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

PCOC2_HUMAN
NC score	0.093906 (rank : 221)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	333	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC1_MOUSE
NC score	0.092809 (rank : 222)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	333	Target Neighborhood Hits	100	Shared Neighborhood Hits	23
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC1_HUMAN
NC score	0.090788 (rank : 223)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	333	Target Neighborhood Hits	146	Shared Neighborhood Hits	24
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC2_MOUSE
NC score	0.090260 (rank : 224)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	333	Target Neighborhood Hits	73	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

LRP5_HUMAN
NC score	0.087867 (rank : 225)	θ value	6.88961 (rank : 312)
Query Neighborhood Hits	333	Target Neighborhood Hits	224	Shared Neighborhood Hits	49
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
NC score	0.086861 (rank : 226)	θ value	5.27518 (rank : 287)
Query Neighborhood Hits	333	Target Neighborhood Hits	236	Shared Neighborhood Hits	45
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

CUZD1_HUMAN
NC score	0.085006 (rank : 227)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	333	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

DCBD1_MOUSE
NC score	0.084289 (rank : 228)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	333	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

C163B_HUMAN
NC score	0.084187 (rank : 229)	θ value	0.365318 (rank : 203)
Query Neighborhood Hits	333	Target Neighborhood Hits	64	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

CUBN_MOUSE
NC score	0.084034 (rank : 230)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	333	Target Neighborhood Hits	477	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

PROS_HUMAN
NC score	0.082189 (rank : 231)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	333	Target Neighborhood Hits	340	Shared Neighborhood Hits	43
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SEZ6L_HUMAN
NC score	0.081542 (rank : 232)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	333	Target Neighborhood Hits	289	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CSMD3_HUMAN
NC score	0.081309 (rank : 233)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	333	Target Neighborhood Hits	199	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

NETO1_MOUSE
NC score	0.080355 (rank : 234)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	333	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CSMD1_MOUSE
NC score	0.080140 (rank : 235)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	333	Target Neighborhood Hits	193	Shared Neighborhood Hits	24
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CUZD1_MOUSE
NC score	0.080072 (rank : 236)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	333	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

CSMD1_HUMAN
NC score	0.079900 (rank : 237)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

NETO1_HUMAN
NC score	0.079453 (rank : 238)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	333	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

GAS6_HUMAN
NC score	0.079383 (rank : 239)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	333	Target Neighborhood Hits	348	Shared Neighborhood Hits	47
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CSMD2_HUMAN
NC score	0.079341 (rank : 240)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	333	Target Neighborhood Hits	188	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

NETO2_HUMAN
NC score	0.079252 (rank : 241)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	333	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
NC score	0.078923 (rank : 242)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	333	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

CUBN_HUMAN
NC score	0.078545 (rank : 243)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	333	Target Neighborhood Hits	482	Shared Neighborhood Hits	50
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CD5L_MOUSE
NC score	0.076590 (rank : 244)	θ value	6.88961 (rank : 306)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QWK4, O35300, O35301, Q505P6, Q91W05	Gene names	Cd5l, Aim, Api6
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (Apoptosis inhibitory 6) (Apoptosis inhibitor expressed by macrophages).

CO9_HUMAN
NC score	0.075748 (rank : 245)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	333	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

PROS_MOUSE
NC score	0.075668 (rank : 246)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	333	Target Neighborhood Hits	330	Shared Neighborhood Hits	40
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LRP11_MOUSE
NC score	0.075554 (rank : 247)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	333	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

SSPO_MOUSE
NC score	0.075518 (rank : 248)	θ value	6.88961 (rank : 316)
Query Neighborhood Hits	333	Target Neighborhood Hits	800	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

GAS6_MOUSE
NC score	0.075182 (rank : 249)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	333	Target Neighborhood Hits	343	Shared Neighborhood Hits	42
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NRP1_MOUSE
NC score	0.074871 (rank : 250)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	333	Target Neighborhood Hits	120	Shared Neighborhood Hits	18
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.074722 (rank : 251)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	333	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP2_MOUSE
NC score	0.074460 (rank : 252)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	333	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_HUMAN
NC score	0.074306 (rank : 253)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	333	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

CO6_HUMAN
NC score	0.074284 (rank : 254)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	333	Target Neighborhood Hits	331	Shared Neighborhood Hits	52
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

LRP11_HUMAN
NC score	0.074188 (rank : 255)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	333	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

CD5L_HUMAN
NC score	0.073205 (rank : 256)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	O43866, Q6UX63	Gene names	CD5L
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (IgM-associated peptide).

PDGFD_HUMAN
NC score	0.070951 (rank : 257)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	333	Target Neighborhood Hits	74	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

IDD_HUMAN
NC score	0.070933 (rank : 258)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	333	Target Neighborhood Hits	127	Shared Neighborhood Hits	35
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

PDGFD_MOUSE
NC score	0.070774 (rank : 259)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	333	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

C163A_MOUSE
NC score	0.070533 (rank : 260)	θ value	1.38821 (rank : 229)
Query Neighborhood Hits	333	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

TSG6_HUMAN
NC score	0.070241 (rank : 261)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	333	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.068973 (rank : 262)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	333	Target Neighborhood Hits	91	Shared Neighborhood Hits	14
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

CO9_MOUSE
NC score	0.068587 (rank : 263)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	333	Target Neighborhood Hits	153	Shared Neighborhood Hits	36
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

C163A_HUMAN
NC score	0.068260 (rank : 264)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	333	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

EGFL8_HUMAN
NC score	0.064289 (rank : 265)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	333	Target Neighborhood Hits	270	Shared Neighborhood Hits	40
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
NC score	0.064013 (rank : 266)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	333	Target Neighborhood Hits	266	Shared Neighborhood Hits	39
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

SPIT1_HUMAN
NC score	0.063734 (rank : 267)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	333	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT1_MOUSE
NC score	0.061939 (rank : 268)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	333	Target Neighborhood Hits	96	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

DCBD1_HUMAN
NC score	0.061666 (rank : 269)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	333	Target Neighborhood Hits	110	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

PGBM_HUMAN
NC score	0.059393 (rank : 270)	θ value	2.36792 (rank : 253)
Query Neighborhood Hits	333	Target Neighborhood Hits	1113	Shared Neighborhood Hits	69
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

DCBD2_HUMAN
NC score	0.059137 (rank : 271)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	333	Target Neighborhood Hits	118	Shared Neighborhood Hits	17
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

LOXL4_HUMAN
NC score	0.057399 (rank : 272)	θ value	4.03905 (rank : 272)
Query Neighborhood Hits	333	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JB6, Q96DY1, Q96PC0, Q9H6T5	Gene names	LOXL4, LOXC
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

CD6_HUMAN
NC score	0.057142 (rank : 273)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	333	Target Neighborhood Hits	65	Shared Neighborhood Hits	23
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

PGBM_MOUSE
NC score	0.056491 (rank : 274)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	333	Target Neighborhood Hits	1073	Shared Neighborhood Hits	60
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LYAM2_HUMAN
NC score	0.056237 (rank : 275)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	333	Target Neighborhood Hits	394	Shared Neighborhood Hits	34
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

DCBD2_MOUSE
NC score	0.055989 (rank : 276)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	333	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

GP126_HUMAN
NC score	0.055900 (rank : 277)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	333	Target Neighborhood Hits	187	Shared Neighborhood Hits	18
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

LG3BP_HUMAN
NC score	0.055124 (rank : 278)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	333	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	Q08380	Gene names	LGALS3BP, M2BP
Domain Architecture
Description	Galectin-3-binding protein precursor (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K).

CD6_MOUSE
NC score	0.054827 (rank : 279)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	333	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

LOXL4_MOUSE
NC score	0.054803 (rank : 280)	θ value	4.03905 (rank : 273)
Query Neighborhood Hits	333	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q924C6	Gene names	Loxl4, Loxc
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

CO8A_MOUSE
NC score	0.054338 (rank : 281)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	333	Target Neighborhood Hits	182	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

C4BB_HUMAN
NC score	0.053788 (rank : 282)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	333	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

EGFL7_HUMAN
NC score	0.053755 (rank : 283)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	333	Target Neighborhood Hits	325	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

LYAM2_MOUSE
NC score	0.053075 (rank : 284)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	333	Target Neighborhood Hits	420	Shared Neighborhood Hits	40
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_MOUSE
NC score	0.052613 (rank : 285)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	333	Target Neighborhood Hits	390	Shared Neighborhood Hits	38
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LCE3B_HUMAN
NC score	0.052408 (rank : 286)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LOXL2_HUMAN
NC score	0.051983 (rank : 287)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y4K0, Q9BW70, Q9Y5Y8	Gene names	LOXL2
Domain Architecture
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14).

LOXL3_HUMAN
NC score	0.051951 (rank : 288)	θ value	4.03905 (rank : 271)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P58215, Q96RS1	Gene names	LOXL3, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3).

LOXL3_MOUSE
NC score	0.051937 (rank : 289)	θ value	8.99809 (rank : 326)
Query Neighborhood Hits	333	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z175, Q9JJ39	Gene names	Loxl3, Lor2
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2).

LOXL2_MOUSE
NC score	0.051051 (rank : 290)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	333	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	P58022, Q8BRE6, Q8BS86, Q8C4K0, Q9JJ39	Gene names	Loxl2
Domain Architecture	No domain graphic available
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2).

MSRE_HUMAN
NC score	0.037580 (rank : 291)	θ value	4.03905 (rank : 275)
Query Neighborhood Hits	333	Target Neighborhood Hits	298	Shared Neighborhood Hits	21
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

NACAM_MOUSE
NC score	0.026667 (rank : 292)	θ value	0.000270298 (rank : 174)
Query Neighborhood Hits	333	Target Neighborhood Hits	1866	Shared Neighborhood Hits	107
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OGFR_HUMAN
NC score	0.024369 (rank : 293)	θ value	2.21117e-06 (rank : 173)
Query Neighborhood Hits	333	Target Neighborhood Hits	1582	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SELPL_MOUSE
NC score	0.023922 (rank : 294)	θ value	0.0736092 (rank : 187)
Query Neighborhood Hits	333	Target Neighborhood Hits	588	Shared Neighborhood Hits	56
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SRRM1_MOUSE
NC score	0.023541 (rank : 295)	θ value	0.47712 (rank : 214)
Query Neighborhood Hits	333	Target Neighborhood Hits	966	Shared Neighborhood Hits	75
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

GTSE1_MOUSE
NC score	0.022797 (rank : 296)	θ value	0.125558 (rank : 190)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

TARA_HUMAN
NC score	0.022677 (rank : 297)	θ value	0.000786445 (rank : 178)
Query Neighborhood Hits	333	Target Neighborhood Hits	1626	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MUC1_MOUSE
NC score	0.022331 (rank : 298)	θ value	5.27518 (rank : 288)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SF3B1_HUMAN
NC score	0.021888 (rank : 299)	θ value	0.279714 (rank : 200)
Query Neighborhood Hits	333	Target Neighborhood Hits	341	Shared Neighborhood Hits	37
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.021854 (rank : 300)	θ value	0.279714 (rank : 201)
Query Neighborhood Hits	333	Target Neighborhood Hits	352	Shared Neighborhood Hits	37
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

PHC2_MOUSE
NC score	0.020512 (rank : 301)	θ value	0.125558 (rank : 191)
Query Neighborhood Hits	333	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PHC2_HUMAN
NC score	0.020252 (rank : 302)	θ value	0.0252991 (rank : 181)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

BSN_MOUSE
NC score	0.020157 (rank : 303)	θ value	0.0736092 (rank : 184)
Query Neighborhood Hits	333	Target Neighborhood Hits	2057	Shared Neighborhood Hits	106
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SRRM2_MOUSE
NC score	0.019847 (rank : 304)	θ value	0.21417 (rank : 198)
Query Neighborhood Hits	333	Target Neighborhood Hits	1470	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BSN_HUMAN
NC score	0.019233 (rank : 305)	θ value	2.36792 (rank : 244)
Query Neighborhood Hits	333	Target Neighborhood Hits	1537	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MAP4_MOUSE
NC score	0.018811 (rank : 306)	θ value	2.36792 (rank : 251)
Query Neighborhood Hits	333	Target Neighborhood Hits	409	Shared Neighborhood Hits	47
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MUC5B_HUMAN
NC score	0.018617 (rank : 307)	θ value	8.99809 (rank : 330)
Query Neighborhood Hits	333	Target Neighborhood Hits	1020	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TARA_MOUSE
NC score	0.018092 (rank : 308)	θ value	1.06291 (rank : 226)
Query Neighborhood Hits	333	Target Neighborhood Hits	1133	Shared Neighborhood Hits	62
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LSD1_HUMAN
NC score	0.017762 (rank : 309)	θ value	0.0193708 (rank : 180)
Query Neighborhood Hits	333	Target Neighborhood Hits	455	Shared Neighborhood Hits	23
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

CRSP2_HUMAN
NC score	0.017434 (rank : 310)	θ value	1.06291 (rank : 222)
Query Neighborhood Hits	333	Target Neighborhood Hits	380	Shared Neighborhood Hits	40
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

DOS_HUMAN
NC score	0.016201 (rank : 311)	θ value	1.06291 (rank : 223)
Query Neighborhood Hits	333	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

CT151_HUMAN
NC score	0.016084 (rank : 312)	θ value	2.36792 (rank : 245)
Query Neighborhood Hits	333	Target Neighborhood Hits	382	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

PCLO_MOUSE
NC score	0.016025 (rank : 313)	θ value	0.0330416 (rank : 182)
Query Neighborhood Hits	333	Target Neighborhood Hits	2275	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PHC1_HUMAN
NC score	0.015438 (rank : 314)	θ value	5.27518 (rank : 294)
Query Neighborhood Hits	333	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

NCOA2_MOUSE
NC score	0.015130 (rank : 315)	θ value	0.0961366 (rank : 188)
Query Neighborhood Hits	333	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

LAD1_HUMAN
NC score	0.014377 (rank : 316)	θ value	0.279714 (rank : 199)
Query Neighborhood Hits	333	Target Neighborhood Hits	441	Shared Neighborhood Hits	34
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

RFIP5_MOUSE
NC score	0.013991 (rank : 317)	θ value	0.163984 (rank : 194)
Query Neighborhood Hits	333	Target Neighborhood Hits	126	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

IL3RB_MOUSE
NC score	0.013790 (rank : 318)	θ value	0.365318 (rank : 205)
Query Neighborhood Hits	333	Target Neighborhood Hits	355	Shared Neighborhood Hits	28
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

BIN1_HUMAN
NC score	0.013754 (rank : 319)	θ value	0.47712 (rank : 211)
Query Neighborhood Hits	333	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

PPRB_HUMAN
NC score	0.013645 (rank : 320)	θ value	2.36792 (rank : 254)
Query Neighborhood Hits	333	Target Neighborhood Hits	311	Shared Neighborhood Hits	36
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

BAG3_MOUSE
NC score	0.013640 (rank : 321)	θ value	1.81305 (rank : 235)
Query Neighborhood Hits	333	Target Neighborhood Hits	513	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MUC1_HUMAN
NC score	0.013625 (rank : 322)	θ value	0.0113563 (rank : 179)
Query Neighborhood Hits	333	Target Neighborhood Hits	975	Shared Neighborhood Hits	65
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ZN750_MOUSE
NC score	0.013166 (rank : 323)	θ value	3.0926 (rank : 264)
Query Neighborhood Hits	333	Target Neighborhood Hits	346	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

SC24C_HUMAN
NC score	0.012873 (rank : 324)	θ value	0.0736092 (rank : 186)
Query Neighborhood Hits	333	Target Neighborhood Hits	662	Shared Neighborhood Hits	49
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

BIN1_MOUSE
NC score	0.012861 (rank : 325)	θ value	0.813845 (rank : 217)
Query Neighborhood Hits	333	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BAP1_HUMAN
NC score	0.012641 (rank : 326)	θ value	0.62314 (rank : 215)
Query Neighborhood Hits	333	Target Neighborhood Hits	106	Shared Neighborhood Hits	14
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

IL3B2_MOUSE
NC score	0.012430 (rank : 327)	θ value	0.365318 (rank : 204)
Query Neighborhood Hits	333	Target Neighborhood Hits	372	Shared Neighborhood Hits	27
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

DACT1_HUMAN
NC score	0.012421 (rank : 328)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	333	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

AFF4_MOUSE
NC score	0.012326 (rank : 329)	θ value	0.21417 (rank : 195)
Query Neighborhood Hits	333	Target Neighborhood Hits	581	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

APC_HUMAN
NC score	0.012163 (rank : 330)	θ value	3.0926 (rank : 255)
Query Neighborhood Hits	333	Target Neighborhood Hits	603	Shared Neighborhood Hits	41
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

GRIN2_HUMAN
NC score	0.012112 (rank : 331)	θ value	5.27518 (rank : 284)
Query Neighborhood Hits	333	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

RP1L1_HUMAN
NC score	0.012060 (rank : 332)	θ value	0.21417 (rank : 197)
Query Neighborhood Hits	333	Target Neighborhood Hits	1072	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TM108_MOUSE
NC score	0.012026 (rank : 333)	θ value	8.99809 (rank : 333)
Query Neighborhood Hits	333	Target Neighborhood Hits	336	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ZN541_HUMAN
NC score	0.012026 (rank : 334)	θ value	0.365318 (rank : 210)
Query Neighborhood Hits	333	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

CIC_MOUSE
NC score	0.011323 (rank : 335)	θ value	3.0926 (rank : 256)
Query Neighborhood Hits	333	Target Neighborhood Hits	742	Shared Neighborhood Hits	68
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

NCOA2_HUMAN
NC score	0.010871 (rank : 336)	θ value	1.38821 (rank : 231)
Query Neighborhood Hits	333	Target Neighborhood Hits	281	Shared Neighborhood Hits	21
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PI5PA_HUMAN
NC score	0.010760 (rank : 337)	θ value	4.03905 (rank : 277)
Query Neighborhood Hits	333	Target Neighborhood Hits	749	Shared Neighborhood Hits	61
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PDZD2_HUMAN
NC score	0.010737 (rank : 338)	θ value	1.38821 (rank : 232)
Query Neighborhood Hits	333	Target Neighborhood Hits	772	Shared Neighborhood Hits	52
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PHF12_MOUSE
NC score	0.010559 (rank : 339)	θ value	0.365318 (rank : 207)
Query Neighborhood Hits	333	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

SMOO_HUMAN
NC score	0.010558 (rank : 340)	θ value	1.81305 (rank : 242)
Query Neighborhood Hits	333	Target Neighborhood Hits	391	Shared Neighborhood Hits	40
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

BCLF1_MOUSE
NC score	0.010505 (rank : 341)	θ value	1.81305 (rank : 236)
Query Neighborhood Hits	333	Target Neighborhood Hits	303	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BAT2_MOUSE
NC score	0.010344 (rank : 342)	θ value	5.27518 (rank : 281)
Query Neighborhood Hits	333	Target Neighborhood Hits	947	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ASTL_HUMAN
NC score	0.010266 (rank : 343)	θ value	0.125558 (rank : 189)
Query Neighborhood Hits	333	Target Neighborhood Hits	252	Shared Neighborhood Hits	21
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BAP1_MOUSE
NC score	0.010204 (rank : 344)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	333	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

ZN750_HUMAN
NC score	0.010151 (rank : 345)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	333	Target Neighborhood Hits	183	Shared Neighborhood Hits	22
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

NCOR2_HUMAN
NC score	0.009973 (rank : 346)	θ value	5.27518 (rank : 289)
Query Neighborhood Hits	333	Target Neighborhood Hits	870	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

EVL_MOUSE
NC score	0.009806 (rank : 347)	θ value	2.36792 (rank : 247)
Query Neighborhood Hits	333	Target Neighborhood Hits	203	Shared Neighborhood Hits	26
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

MBB1A_HUMAN
NC score	0.009722 (rank : 348)	θ value	1.81305 (rank : 240)
Query Neighborhood Hits	333	Target Neighborhood Hits	665	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

EVL_HUMAN
NC score	0.009564 (rank : 349)	θ value	4.03905 (rank : 268)
Query Neighborhood Hits	333	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

AFF4_HUMAN
NC score	0.008658 (rank : 350)	θ value	6.88961 (rank : 304)
Query Neighborhood Hits	333	Target Neighborhood Hits	611	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

UBP36_HUMAN
NC score	0.008071 (rank : 351)	θ value	3.0926 (rank : 263)
Query Neighborhood Hits	333	Target Neighborhood Hits	232	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

MAGD4_HUMAN
NC score	0.007994 (rank : 352)	θ value	1.81305 (rank : 239)
Query Neighborhood Hits	333	Target Neighborhood Hits	338	Shared Neighborhood Hits	34
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

DNL1_HUMAN
NC score	0.007787 (rank : 353)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	333	Target Neighborhood Hits	216	Shared Neighborhood Hits	21
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

PHF12_HUMAN
NC score	0.007783 (rank : 354)	θ value	4.03905 (rank : 276)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CBP_MOUSE
NC score	0.007702 (rank : 355)	θ value	5.27518 (rank : 282)
Query Neighborhood Hits	333	Target Neighborhood Hits	1051	Shared Neighborhood Hits	75
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RGS3_MOUSE
NC score	0.007444 (rank : 356)	θ value	0.125558 (rank : 192)
Query Neighborhood Hits	333	Target Neighborhood Hits	1621	Shared Neighborhood Hits	81
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MAML1_MOUSE
NC score	0.007325 (rank : 357)	θ value	3.0926 (rank : 258)
Query Neighborhood Hits	333	Target Neighborhood Hits	279	Shared Neighborhood Hits	30
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SYNPO_MOUSE
NC score	0.007083 (rank : 358)	θ value	8.99809 (rank : 332)
Query Neighborhood Hits	333	Target Neighborhood Hits	242	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

MINT_MOUSE
NC score	0.006959 (rank : 359)	θ value	1.81305 (rank : 241)
Query Neighborhood Hits	333	Target Neighborhood Hits	1514	Shared Neighborhood Hits	71
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOR2_MOUSE
NC score	0.006675 (rank : 360)	θ value	6.88961 (rank : 314)
Query Neighborhood Hits	333	Target Neighborhood Hits	790	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

HRBL_MOUSE
NC score	0.006663 (rank : 361)	θ value	0.47712 (rank : 212)
Query Neighborhood Hits	333	Target Neighborhood Hits	269	Shared Neighborhood Hits	19
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

S23IP_MOUSE
NC score	0.006607 (rank : 362)	θ value	4.03905 (rank : 278)
Query Neighborhood Hits	333	Target Neighborhood Hits	363	Shared Neighborhood Hits	30
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

PO210_HUMAN
NC score	0.006573 (rank : 363)	θ value	1.38821 (rank : 233)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEM1, O94980, Q6NXG6, Q8NBJ1, Q9H6C8, Q9UFP3	Gene names	NUP210, KIAA0906
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210 precursor (POM210) (Nuclear pore protein gp210).

SAPS1_HUMAN
NC score	0.006556 (rank : 364)	θ value	4.03905 (rank : 279)
Query Neighborhood Hits	333	Target Neighborhood Hits	704	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ZC3H6_MOUSE
NC score	0.006360 (rank : 365)	θ value	1.06291 (rank : 227)
Query Neighborhood Hits	333	Target Neighborhood Hits	239	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

DACT1_MOUSE
NC score	0.006050 (rank : 366)	θ value	6.88961 (rank : 309)
Query Neighborhood Hits	333	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

NQO1_HUMAN
NC score	0.005871 (rank : 367)	θ value	5.27518 (rank : 290)
Query Neighborhood Hits	333	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P15559, Q86UK1	Gene names	NQO1, DIA4, NMOR1
Domain Architecture
Description	NAD(P)H dehydrogenase [quinone] 1 (EC 1.6.5.2) (Quinone reductase 1) (NAD(P)H:quinone oxidoreductase 1) (QR1) (DT-diaphorase) (DTD) (Azoreductase) (Phylloquinone reductase) (Menadione reductase).

DEN1A_HUMAN
NC score	0.005734 (rank : 368)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DEN1A_MOUSE
NC score	0.005504 (rank : 369)	θ value	5.27518 (rank : 283)
Query Neighborhood Hits	333	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

NFH_MOUSE
NC score	0.005504 (rank : 370)	θ value	0.000602161 (rank : 175)
Query Neighborhood Hits	333	Target Neighborhood Hits	2247	Shared Neighborhood Hits	91
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GRIP2_HUMAN
NC score	0.005328 (rank : 371)	θ value	0.0736092 (rank : 185)
Query Neighborhood Hits	333	Target Neighborhood Hits	256	Shared Neighborhood Hits	12
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

MAGE1_HUMAN
NC score	0.005270 (rank : 372)	θ value	0.365318 (rank : 206)
Query Neighborhood Hits	333	Target Neighborhood Hits	1389	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

YAP1_HUMAN
NC score	0.005253 (rank : 373)	θ value	5.27518 (rank : 300)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	24
SwissProt Accessions	P46937	Gene names	YAP1, YAP65
Domain Architecture
Description	65 kDa Yes-associated protein (YAP65).

RGS3_HUMAN
NC score	0.005057 (rank : 374)	θ value	0.365318 (rank : 208)
Query Neighborhood Hits	333	Target Neighborhood Hits	1375	Shared Neighborhood Hits	68
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

JPH2_HUMAN
NC score	0.005013 (rank : 375)	θ value	5.27518 (rank : 286)
Query Neighborhood Hits	333	Target Neighborhood Hits	639	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

PALM_MOUSE
NC score	0.004933 (rank : 376)	θ value	5.27518 (rank : 293)
Query Neighborhood Hits	333	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

CTND2_HUMAN
NC score	0.004830 (rank : 377)	θ value	6.88961 (rank : 308)
Query Neighborhood Hits	333	Target Neighborhood Hits	333	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

NUP53_HUMAN
NC score	0.004589 (rank : 378)	θ value	5.27518 (rank : 291)
Query Neighborhood Hits	333	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

S6A18_HUMAN
NC score	0.004168 (rank : 379)	θ value	0.365318 (rank : 209)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q96N87	Gene names	SLC6A18, XTRP2
Domain Architecture
Description	Sodium- and chloride-dependent transporter XTRP2 (Solute carrier family 6 member 18).

RP3A_MOUSE
NC score	0.004032 (rank : 380)	θ value	5.27518 (rank : 295)
Query Neighborhood Hits	333	Target Neighborhood Hits	510	Shared Neighborhood Hits	39
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

ZNHI4_MOUSE
NC score	0.003889 (rank : 381)	θ value	6.88961 (rank : 317)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PT3, Q9CY38	Gene names	Znhit4, Hmga1l4, Papa1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

FOXE2_HUMAN
NC score	0.003625 (rank : 382)	θ value	0.21417 (rank : 196)
Query Neighborhood Hits	333	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

TBX3_MOUSE
NC score	0.003616 (rank : 383)	θ value	0.279714 (rank : 202)
Query Neighborhood Hits	333	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

IQEC3_MOUSE
NC score	0.003221 (rank : 384)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	333	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

K1802_MOUSE
NC score	0.003105 (rank : 385)	θ value	4.03905 (rank : 270)
Query Neighborhood Hits	333	Target Neighborhood Hits	1596	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

COA2_HUMAN
NC score	0.002735 (rank : 386)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	333	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

ELL_HUMAN
NC score	0.002550 (rank : 387)	θ value	6.88961 (rank : 310)
Query Neighborhood Hits	333	Target Neighborhood Hits	183	Shared Neighborhood Hits	9
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

FOXK2_HUMAN
NC score	0.002459 (rank : 388)	θ value	0.62314 (rank : 216)
Query Neighborhood Hits	333	Target Neighborhood Hits	190	Shared Neighborhood Hits	13
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

FHOD1_MOUSE
NC score	0.002090 (rank : 389)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	333	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

WFDC8_HUMAN
NC score	0.002036 (rank : 390)	θ value	5.27518 (rank : 299)
Query Neighborhood Hits	333	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

CRCM1_HUMAN
NC score	0.001889 (rank : 391)	θ value	6.88961 (rank : 307)
Query Neighborhood Hits	333	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q96D31, Q3MHV3, Q6DHX2, Q96BP7, Q96K71	Gene names	TMEM142A, CRACM1, ORAI1
Domain Architecture	No domain graphic available
Description	Calcium release-activated calcium channel protein 1 (Transmembrane protein 142A) (Protein orai-1).

PDLI4_HUMAN
NC score	0.001760 (rank : 392)	θ value	8.99809 (rank : 331)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

SC6A5_MOUSE
NC score	0.001507 (rank : 393)	θ value	3.0926 (rank : 262)
Query Neighborhood Hits	333	Target Neighborhood Hits	135	Shared Neighborhood Hits	17
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

ADA19_HUMAN
NC score	0.001461 (rank : 394)	θ value	2.36792 (rank : 243)
Query Neighborhood Hits	333	Target Neighborhood Hits	381	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

MCM2_HUMAN
NC score	0.001184 (rank : 395)	θ value	4.03905 (rank : 274)
Query Neighborhood Hits	333	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7	Gene names	MCM2, BM28, CDCL1, KIAA0030
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

BIM_HUMAN
NC score	0.001168 (rank : 396)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	333	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	O43521, O43522	Gene names	BCL2L11, BIM
Domain Architecture
Description	Bcl-2-like protein 11 (Bcl2-interacting mediator of cell death).

PTPRG_MOUSE
NC score	0.000998 (rank : 397)	θ value	0.813845 (rank : 220)
Query Neighborhood Hits	333	Target Neighborhood Hits	260	Shared Neighborhood Hits	13
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

SOX30_HUMAN
NC score	0.000930 (rank : 398)	θ value	5.27518 (rank : 297)
Query Neighborhood Hits	333	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

ITA7_HUMAN
NC score	0.000867 (rank : 399)	θ value	4.03905 (rank : 269)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q13683, O43197, Q9NY89, Q9UET0, Q9UEV2	Gene names	ITGA7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

ITA7_MOUSE
NC score	0.000750 (rank : 400)	θ value	5.27518 (rank : 285)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q61738, O88731, O88732, P70350, Q61737, Q61741	Gene names	Itga7
Domain Architecture
Description	Integrin alpha-7 precursor [Contains: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain].

KCNH2_MOUSE
NC score	0.000629 (rank : 401)	θ value	6.88961 (rank : 311)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

MYCL1_HUMAN
NC score	0.000421 (rank : 402)	θ value	6.88961 (rank : 313)
Query Neighborhood Hits	333	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MLL3_HUMAN
NC score	-0.000028 (rank : 403)	θ value	3.0926 (rank : 259)
Query Neighborhood Hits	333	Target Neighborhood Hits	1644	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DDX51_HUMAN
NC score	-0.000059 (rank : 404)	θ value	2.36792 (rank : 246)
Query Neighborhood Hits	333	Target Neighborhood Hits	332	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

INVS_MOUSE
NC score	-0.000739 (rank : 405)	θ value	1.38821 (rank : 230)
Query Neighborhood Hits	333	Target Neighborhood Hits	609	Shared Neighborhood Hits	42
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

SOX10_HUMAN
NC score	-0.000910 (rank : 406)	θ value	5.27518 (rank : 296)
Query Neighborhood Hits	333	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

BEGIN_HUMAN
NC score	-0.001854 (rank : 407)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	333	Target Neighborhood Hits	454	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

EHMT2_MOUSE
NC score	-0.005119 (rank : 408)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	333	Target Neighborhood Hits	750	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

RTN4R_MOUSE
NC score	-0.005237 (rank : 409)	θ value	6.88961 (rank : 315)
Query Neighborhood Hits	333	Target Neighborhood Hits	293	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

ZFHX2_HUMAN
NC score	-0.005454 (rank : 410)	θ value	0.813845 (rank : 221)
Query Neighborhood Hits	333	Target Neighborhood Hits	1178	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

SPEG_MOUSE
NC score	-0.005467 (rank : 411)	θ value	0.47712 (rank : 213)
Query Neighborhood Hits	333	Target Neighborhood Hits	1959	Shared Neighborhood Hits	72
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

FOG1_MOUSE
NC score	-0.005661 (rank : 412)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	333	Target Neighborhood Hits	1237	Shared Neighborhood Hits	57
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

SPEG_HUMAN
NC score	-0.005860 (rank : 413)	θ value	0.125558 (rank : 193)
Query Neighborhood Hits	333	Target Neighborhood Hits	1762	Shared Neighborhood Hits	68
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MY18B_HUMAN
NC score	-0.006223 (rank : 414)	θ value	3.0926 (rank : 260)
Query Neighborhood Hits	333	Target Neighborhood Hits	1299	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

WNK2_HUMAN
NC score	-0.006926 (rank : 415)	θ value	4.03905 (rank : 280)
Query Neighborhood Hits	333	Target Neighborhood Hits	1407	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MK15_HUMAN
NC score	-0.007396 (rank : 416)	θ value	0.0431538 (rank : 183)
Query Neighborhood Hits	333	Target Neighborhood Hits	1038	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

MAST4_HUMAN
NC score	-0.007834 (rank : 417)	θ value	2.36792 (rank : 252)
Query Neighborhood Hits	333	Target Neighborhood Hits	1804	Shared Neighborhood Hits	76
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RRBP1_MOUSE
NC score	-0.008369 (rank : 418)	θ value	3.0926 (rank : 261)
Query Neighborhood Hits	333	Target Neighborhood Hits	1650	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

GAK_HUMAN
NC score	-0.009333 (rank : 419)	θ value	1.81305 (rank : 237)
Query Neighborhood Hits	333	Target Neighborhood Hits	1028	Shared Neighborhood Hits	22
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

ZN516_MOUSE
NC score	-0.010668 (rank : 420)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	333	Target Neighborhood Hits	1197	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

OBSCN_HUMAN
NC score	-0.011404 (rank : 421)	θ value	5.27518 (rank : 292)
Query Neighborhood Hits	333	Target Neighborhood Hits	1931	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TLK2_HUMAN
NC score	-0.011422 (rank : 422)	θ value	5.27518 (rank : 298)
Query Neighborhood Hits	333	Target Neighborhood Hits	1044	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

ZFP28_HUMAN
NC score	-0.012388 (rank : 423)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	333	Target Neighborhood Hits	843	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

STK10_HUMAN
NC score	-0.014134 (rank : 424)	θ value	1.38821 (rank : 234)
Query Neighborhood Hits	333	Target Neighborhood Hits	1921	Shared Neighborhood Hits	34
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).