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Network neighborhood for query Sequence : PDLI4_HUMAN

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PDLI4_HUMAN
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDLI4_HUMAN
θ value	1.01004e-176 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	245	Target Neighborhood Hits	245	Shared Neighborhood Hits	245
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	2.11095e-166 (rank : 2)	NC score	0.990878 (rank : 2)
Query Neighborhood Hits	245	Target Neighborhood Hits	233	Shared Neighborhood Hits	210
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI1_HUMAN
θ value	1.66191e-70 (rank : 3)	NC score	0.937006 (rank : 5)
Query Neighborhood Hits	245	Target Neighborhood Hits	242	Shared Neighborhood Hits	166
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	4.09345e-69 (rank : 4)	NC score	0.931349 (rank : 6)
Query Neighborhood Hits	245	Target Neighborhood Hits	213	Shared Neighborhood Hits	157
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI3_MOUSE
θ value	1.00825e-67 (rank : 5)	NC score	0.951957 (rank : 4)
Query Neighborhood Hits	245	Target Neighborhood Hits	197	Shared Neighborhood Hits	179
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_HUMAN
θ value	1.11475e-66 (rank : 6)	NC score	0.952019 (rank : 3)
Query Neighborhood Hits	245	Target Neighborhood Hits	199	Shared Neighborhood Hits	182
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI2_HUMAN
θ value	4.13158e-37 (rank : 7)	NC score	0.867712 (rank : 8)
Query Neighborhood Hits	245	Target Neighborhood Hits	245	Shared Neighborhood Hits	164
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI2_MOUSE
θ value	1.24399e-33 (rank : 8)	NC score	0.871008 (rank : 7)
Query Neighborhood Hits	245	Target Neighborhood Hits	220	Shared Neighborhood Hits	162
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI7_HUMAN
θ value	7.56453e-23 (rank : 9)	NC score	0.725064 (rank : 10)
Query Neighborhood Hits	245	Target Neighborhood Hits	547	Shared Neighborhood Hits	196
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LDB3_MOUSE
θ value	1.42661e-21 (rank : 10)	NC score	0.721389 (rank : 11)
Query Neighborhood Hits	245	Target Neighborhood Hits	510	Shared Neighborhood Hits	189
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LDB3_HUMAN
θ value	3.17815e-21 (rank : 11)	NC score	0.718227 (rank : 13)
Query Neighborhood Hits	245	Target Neighborhood Hits	497	Shared Neighborhood Hits	192
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PDLI5_HUMAN
θ value	2.5182e-18 (rank : 12)	NC score	0.719995 (rank : 12)
Query Neighborhood Hits	245	Target Neighborhood Hits	322	Shared Neighborhood Hits	189
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI7_MOUSE
θ value	2.5182e-18 (rank : 13)	NC score	0.731814 (rank : 9)
Query Neighborhood Hits	245	Target Neighborhood Hits	279	Shared Neighborhood Hits	186
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDLI5_MOUSE
θ value	2.13179e-17 (rank : 14)	NC score	0.717945 (rank : 14)
Query Neighborhood Hits	245	Target Neighborhood Hits	287	Shared Neighborhood Hits	190
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SYNP2_MOUSE
θ value	9.59137e-10 (rank : 15)	NC score	0.520350 (rank : 15)
Query Neighborhood Hits	245	Target Neighborhood Hits	252	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SYNP2_HUMAN
θ value	4.76016e-09 (rank : 16)	NC score	0.509066 (rank : 18)
Query Neighborhood Hits	245	Target Neighborhood Hits	323	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SYP2L_HUMAN
θ value	6.21693e-09 (rank : 17)	NC score	0.515584 (rank : 17)
Query Neighborhood Hits	245	Target Neighborhood Hits	400	Shared Neighborhood Hits	111
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

APXL_HUMAN
θ value	5.81887e-07 (rank : 18)	NC score	0.437771 (rank : 34)
Query Neighborhood Hits	245	Target Neighborhood Hits	553	Shared Neighborhood Hits	88
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

LPXN_HUMAN
θ value	7.59969e-07 (rank : 19)	NC score	0.516324 (rank : 16)
Query Neighborhood Hits	245	Target Neighborhood Hits	159	Shared Neighborhood Hits	108
SwissProt Accessions	O60711	Gene names	LPXN, LDLP
Domain Architecture
Description	Leupaxin.

SYP2L_MOUSE
θ value	9.92553e-07 (rank : 20)	NC score	0.470439 (rank : 25)
Query Neighborhood Hits	245	Target Neighborhood Hits	289	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

LPXN_MOUSE
θ value	2.88788e-06 (rank : 21)	NC score	0.503394 (rank : 19)
Query Neighborhood Hits	245	Target Neighborhood Hits	227	Shared Neighborhood Hits	109
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

ABLM3_HUMAN
θ value	1.43324e-05 (rank : 22)	NC score	0.457107 (rank : 27)
Query Neighborhood Hits	245	Target Neighborhood Hits	293	Shared Neighborhood Hits	119
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM3_MOUSE
θ value	2.44474e-05 (rank : 23)	NC score	0.456877 (rank : 28)
Query Neighborhood Hits	245	Target Neighborhood Hits	294	Shared Neighborhood Hits	120
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

PAXI_HUMAN
θ value	2.44474e-05 (rank : 24)	NC score	0.499797 (rank : 20)
Query Neighborhood Hits	245	Target Neighborhood Hits	173	Shared Neighborhood Hits	110
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

PAXI_MOUSE
θ value	2.44474e-05 (rank : 25)	NC score	0.499779 (rank : 21)
Query Neighborhood Hits	245	Target Neighborhood Hits	176	Shared Neighborhood Hits	109
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

MAGI1_HUMAN
θ value	3.19293e-05 (rank : 26)	NC score	0.334537 (rank : 81)
Query Neighborhood Hits	245	Target Neighborhood Hits	388	Shared Neighborhood Hits	112
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

LIMD1_MOUSE
θ value	5.44631e-05 (rank : 27)	NC score	0.476848 (rank : 23)
Query Neighborhood Hits	245	Target Neighborhood Hits	291	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

LPP_MOUSE
θ value	5.44631e-05 (rank : 28)	NC score	0.443546 (rank : 30)
Query Neighborhood Hits	245	Target Neighborhood Hits	247	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

LASP1_HUMAN
θ value	9.29e-05 (rank : 29)	NC score	0.296294 (rank : 118)
Query Neighborhood Hits	245	Target Neighborhood Hits	293	Shared Neighborhood Hits	99
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ABLM2_HUMAN
θ value	0.000121331 (rank : 30)	NC score	0.448111 (rank : 29)
Query Neighborhood Hits	245	Target Neighborhood Hits	317	Shared Neighborhood Hits	112
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

LASP1_MOUSE
θ value	0.000121331 (rank : 31)	NC score	0.301125 (rank : 112)
Query Neighborhood Hits	245	Target Neighborhood Hits	297	Shared Neighborhood Hits	101
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LPP_HUMAN
θ value	0.000121331 (rank : 32)	NC score	0.396816 (rank : 48)
Query Neighborhood Hits	245	Target Neighborhood Hits	775	Shared Neighborhood Hits	131
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

TRIP6_HUMAN
θ value	0.000121331 (rank : 33)	NC score	0.459400 (rank : 26)
Query Neighborhood Hits	245	Target Neighborhood Hits	228	Shared Neighborhood Hits	101
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

LHX9_HUMAN
θ value	0.000158464 (rank : 34)	NC score	0.328369 (rank : 85)
Query Neighborhood Hits	245	Target Neighborhood Hits	444	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NQ69, Q5VUE3, Q9BYU6, Q9NQ70	Gene names	LHX9
Domain Architecture
Description	LIM/homeobox protein Lhx9.

LHX9_MOUSE
θ value	0.000158464 (rank : 35)	NC score	0.328401 (rank : 84)
Query Neighborhood Hits	245	Target Neighborhood Hits	445	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WUH2, Q9QYQ5, Q9QYQ6, Q9QZ00, Q9WU44	Gene names	Lhx9
Domain Architecture
Description	LIM/homeobox protein Lhx9.

LIMD1_HUMAN
θ value	0.00020696 (rank : 36)	NC score	0.472854 (rank : 24)
Query Neighborhood Hits	245	Target Neighborhood Hits	201	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

TES_MOUSE
θ value	0.00020696 (rank : 37)	NC score	0.435952 (rank : 35)
Query Neighborhood Hits	245	Target Neighborhood Hits	171	Shared Neighborhood Hits	106
SwissProt Accessions	P47226	Gene names	Tes
Domain Architecture
Description	Testin (TES1/TES2).

NHRF2_HUMAN
θ value	0.000270298 (rank : 38)	NC score	0.351639 (rank : 69)
Query Neighborhood Hits	245	Target Neighborhood Hits	197	Shared Neighborhood Hits	106
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
θ value	0.000270298 (rank : 39)	NC score	0.354325 (rank : 66)
Query Neighborhood Hits	245	Target Neighborhood Hits	194	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

TES_HUMAN
θ value	0.000270298 (rank : 40)	NC score	0.430176 (rank : 36)
Query Neighborhood Hits	245	Target Neighborhood Hits	131	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UGI8, Q9GZQ1, Q9HAJ9	Gene names	TES
Domain Architecture
Description	Testin (TESS).

ABLM1_HUMAN
θ value	0.000602161 (rank : 41)	NC score	0.426093 (rank : 38)
Query Neighborhood Hits	245	Target Neighborhood Hits	387	Shared Neighborhood Hits	119
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

ABLM1_MOUSE
θ value	0.00102713 (rank : 42)	NC score	0.427326 (rank : 37)
Query Neighborhood Hits	245	Target Neighborhood Hits	356	Shared Neighborhood Hits	117
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

ABLM2_MOUSE
θ value	0.00102713 (rank : 43)	NC score	0.442219 (rank : 31)
Query Neighborhood Hits	245	Target Neighborhood Hits	306	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BL65, Q6H8P8, Q80WK6, Q8BUT1, Q8BXI7	Gene names	Ablim2
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

NHERF_HUMAN
θ value	0.00102713 (rank : 44)	NC score	0.357829 (rank : 63)
Query Neighborhood Hits	245	Target Neighborhood Hits	190	Shared Neighborhood Hits	106
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PINC_HUMAN
θ value	0.00102713 (rank : 45)	NC score	0.490808 (rank : 22)
Query Neighborhood Hits	245	Target Neighborhood Hits	231	Shared Neighborhood Hits	109
SwissProt Accessions	P48059, Q53TE0, Q9BS44	Gene names	LIMS1
Domain Architecture
Description	Protein PINCH (Particularly interesting new Cys-His protein) (LIM and senescent cell antigen-like domains 1) (NY-REN-48 antigen).

LHX2_HUMAN
θ value	0.00134147 (rank : 46)	NC score	0.318348 (rank : 96)
Query Neighborhood Hits	245	Target Neighborhood Hits	432	Shared Neighborhood Hits	104
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

LHX2_MOUSE
θ value	0.00134147 (rank : 47)	NC score	0.317842 (rank : 97)
Query Neighborhood Hits	245	Target Neighborhood Hits	431	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

NHERF_MOUSE
θ value	0.00175202 (rank : 48)	NC score	0.351706 (rank : 68)
Query Neighborhood Hits	245	Target Neighborhood Hits	195	Shared Neighborhood Hits	106
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

LIMK1_HUMAN
θ value	0.00228821 (rank : 49)	NC score	0.150346 (rank : 191)
Query Neighborhood Hits	245	Target Neighborhood Hits	1005	Shared Neighborhood Hits	160
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

CSRP1_MOUSE
θ value	0.00298849 (rank : 50)	NC score	0.367877 (rank : 58)
Query Neighborhood Hits	245	Target Neighborhood Hits	132	Shared Neighborhood Hits	107
SwissProt Accessions	P97315	Gene names	Csrp1, Crp1, Csrp
Domain Architecture
Description	Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP1) (CRP).

LHX3_HUMAN
θ value	0.00298849 (rank : 51)	NC score	0.307605 (rank : 108)
Query Neighborhood Hits	245	Target Neighborhood Hits	474	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UBR4, Q9NZB5, Q9P0I8, Q9P0I9	Gene names	LHX3
Domain Architecture
Description	LIM/homeobox protein Lhx3.

PRIC2_MOUSE
θ value	0.00298849 (rank : 52)	NC score	0.423441 (rank : 39)
Query Neighborhood Hits	245	Target Neighborhood Hits	185	Shared Neighborhood Hits	108
SwissProt Accessions	Q80Y24	Gene names	Prickle2
Domain Architecture	No domain graphic available
Description	Prickle-like protein 2.

CSRP1_HUMAN
θ value	0.00390308 (rank : 53)	NC score	0.365497 (rank : 60)
Query Neighborhood Hits	245	Target Neighborhood Hits	128	Shared Neighborhood Hits	105
SwissProt Accessions	P21291	Gene names	CSRP1, CSRP, CYRP
Domain Architecture
Description	Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP1) (CRP).

LIMK1_MOUSE
θ value	0.00390308 (rank : 54)	NC score	0.148739 (rank : 193)
Query Neighborhood Hits	245	Target Neighborhood Hits	1008	Shared Neighborhood Hits	157
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

MPDZ_MOUSE
θ value	0.00390308 (rank : 55)	NC score	0.269305 (rank : 144)
Query Neighborhood Hits	245	Target Neighborhood Hits	298	Shared Neighborhood Hits	109
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PRIC2_HUMAN
θ value	0.00390308 (rank : 56)	NC score	0.422759 (rank : 42)
Query Neighborhood Hits	245	Target Neighborhood Hits	197	Shared Neighborhood Hits	108
SwissProt Accessions	Q7Z3G6	Gene names	PRICKLE2
Domain Architecture	No domain graphic available
Description	Prickle-like protein 2.

MPDZ_HUMAN
θ value	0.00509761 (rank : 57)	NC score	0.262267 (rank : 151)
Query Neighborhood Hits	245	Target Neighborhood Hits	261	Shared Neighborhood Hits	108
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

DLG5_HUMAN
θ value	0.00665767 (rank : 58)	NC score	0.144712 (rank : 195)
Query Neighborhood Hits	245	Target Neighborhood Hits	1088	Shared Neighborhood Hits	106
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

FBLI1_HUMAN
θ value	0.00665767 (rank : 59)	NC score	0.442119 (rank : 32)
Query Neighborhood Hits	245	Target Neighborhood Hits	200	Shared Neighborhood Hits	106
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

FHL1_MOUSE
θ value	0.00665767 (rank : 60)	NC score	0.395814 (rank : 49)
Query Neighborhood Hits	245	Target Neighborhood Hits	462	Shared Neighborhood Hits	119
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

MAGI1_MOUSE
θ value	0.00665767 (rank : 61)	NC score	0.316513 (rank : 101)
Query Neighborhood Hits	245	Target Neighborhood Hits	403	Shared Neighborhood Hits	111
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI2_HUMAN
θ value	0.00665767 (rank : 62)	NC score	0.326481 (rank : 88)
Query Neighborhood Hits	245	Target Neighborhood Hits	373	Shared Neighborhood Hits	114
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	0.00665767 (rank : 63)	NC score	0.317346 (rank : 98)
Query Neighborhood Hits	245	Target Neighborhood Hits	370	Shared Neighborhood Hits	113
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

LHX3_MOUSE
θ value	0.00869519 (rank : 64)	NC score	0.309015 (rank : 107)
Query Neighborhood Hits	245	Target Neighborhood Hits	451	Shared Neighborhood Hits	108
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

NRAP_HUMAN
θ value	0.00869519 (rank : 65)	NC score	0.228771 (rank : 161)
Query Neighborhood Hits	245	Target Neighborhood Hits	159	Shared Neighborhood Hits	98
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

LHX4_HUMAN
θ value	0.0113563 (rank : 66)	NC score	0.312290 (rank : 105)
Query Neighborhood Hits	245	Target Neighborhood Hits	455	Shared Neighborhood Hits	106
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LHX4_MOUSE
θ value	0.0113563 (rank : 67)	NC score	0.312424 (rank : 104)
Query Neighborhood Hits	245	Target Neighborhood Hits	457	Shared Neighborhood Hits	106
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

PDZD1_MOUSE
θ value	0.0113563 (rank : 68)	NC score	0.288360 (rank : 126)
Query Neighborhood Hits	245	Target Neighborhood Hits	191	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD7_HUMAN
θ value	0.0113563 (rank : 69)	NC score	0.383834 (rank : 53)
Query Neighborhood Hits	245	Target Neighborhood Hits	181	Shared Neighborhood Hits	108
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

SNTA1_MOUSE
θ value	0.0113563 (rank : 70)	NC score	0.313264 (rank : 102)
Query Neighborhood Hits	245	Target Neighborhood Hits	170	Shared Neighborhood Hits	104
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

ZYX_MOUSE
θ value	0.0113563 (rank : 71)	NC score	0.422331 (rank : 43)
Query Neighborhood Hits	245	Target Neighborhood Hits	347	Shared Neighborhood Hits	116
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

LIMA1_MOUSE
θ value	0.0148317 (rank : 72)	NC score	0.277443 (rank : 136)
Query Neighborhood Hits	245	Target Neighborhood Hits	298	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

RPGF6_HUMAN
θ value	0.0148317 (rank : 73)	NC score	0.230020 (rank : 160)
Query Neighborhood Hits	245	Target Neighborhood Hits	266	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

ARVC_HUMAN
θ value	0.0193708 (rank : 74)	NC score	0.036198 (rank : 292)
Query Neighborhood Hits	245	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

GRASP_HUMAN
θ value	0.0193708 (rank : 75)	NC score	0.283818 (rank : 133)
Query Neighborhood Hits	245	Target Neighborhood Hits	147	Shared Neighborhood Hits	98
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	0.0193708 (rank : 76)	NC score	0.281915 (rank : 135)
Query Neighborhood Hits	245	Target Neighborhood Hits	131	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

LIN7A_HUMAN
θ value	0.0193708 (rank : 77)	NC score	0.362253 (rank : 61)
Query Neighborhood Hits	245	Target Neighborhood Hits	193	Shared Neighborhood Hits	107
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	0.0193708 (rank : 78)	NC score	0.361827 (rank : 62)
Query Neighborhood Hits	245	Target Neighborhood Hits	193	Shared Neighborhood Hits	107
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

NRAP_MOUSE
θ value	0.0193708 (rank : 79)	NC score	0.228060 (rank : 162)
Query Neighborhood Hits	245	Target Neighborhood Hits	167	Shared Neighborhood Hits	91
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

SNTA1_HUMAN
θ value	0.0193708 (rank : 80)	NC score	0.312867 (rank : 103)
Query Neighborhood Hits	245	Target Neighborhood Hits	186	Shared Neighborhood Hits	105
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

WHRN_HUMAN
θ value	0.0193708 (rank : 81)	NC score	0.338436 (rank : 80)
Query Neighborhood Hits	245	Target Neighborhood Hits	325	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	0.0193708 (rank : 82)	NC score	0.339157 (rank : 77)
Query Neighborhood Hits	245	Target Neighborhood Hits	412	Shared Neighborhood Hits	119
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

LMCD1_MOUSE
θ value	0.0252991 (rank : 83)	NC score	0.369387 (rank : 57)
Query Neighborhood Hits	245	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VEE1	Gene names	Lmcd1
Domain Architecture
Description	LIM and cysteine-rich domains protein 1.

MAST1_MOUSE
θ value	0.0252991 (rank : 84)	NC score	0.048187 (rank : 281)
Query Neighborhood Hits	245	Target Neighborhood Hits	1123	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SNTG1_MOUSE
θ value	0.0252991 (rank : 85)	NC score	0.322564 (rank : 89)
Query Neighborhood Hits	245	Target Neighborhood Hits	179	Shared Neighborhood Hits	106
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ZYX_HUMAN
θ value	0.0252991 (rank : 86)	NC score	0.422891 (rank : 41)
Query Neighborhood Hits	245	Target Neighborhood Hits	387	Shared Neighborhood Hits	121
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

FHL5_MOUSE
θ value	0.0330416 (rank : 87)	NC score	0.388421 (rank : 52)
Query Neighborhood Hits	245	Target Neighborhood Hits	463	Shared Neighborhood Hits	114
SwissProt Accessions	Q9WTX7	Gene names	Fhl5, Act
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

ISL2_HUMAN
θ value	0.0330416 (rank : 88)	NC score	0.298059 (rank : 115)
Query Neighborhood Hits	245	Target Neighborhood Hits	435	Shared Neighborhood Hits	99
SwissProt Accessions	Q96A47	Gene names	ISL2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

PDZD1_HUMAN
θ value	0.0330416 (rank : 89)	NC score	0.290681 (rank : 122)
Query Neighborhood Hits	245	Target Neighborhood Hits	190	Shared Neighborhood Hits	103
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SNTG1_HUMAN
θ value	0.0330416 (rank : 90)	NC score	0.319839 (rank : 93)
Query Neighborhood Hits	245	Target Neighborhood Hits	181	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ARVC_MOUSE
θ value	0.0431538 (rank : 91)	NC score	0.035464 (rank : 293)
Query Neighborhood Hits	245	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

FBLI1_MOUSE
θ value	0.0431538 (rank : 92)	NC score	0.438173 (rank : 33)
Query Neighborhood Hits	245	Target Neighborhood Hits	228	Shared Neighborhood Hits	113
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

ISL2_MOUSE
θ value	0.0431538 (rank : 93)	NC score	0.295198 (rank : 119)
Query Neighborhood Hits	245	Target Neighborhood Hits	426	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CXV0	Gene names	Isl2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

LIMA1_HUMAN
θ value	0.0431538 (rank : 94)	NC score	0.267351 (rank : 147)
Query Neighborhood Hits	245	Target Neighborhood Hits	309	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

PTN3_HUMAN
θ value	0.0431538 (rank : 95)	NC score	0.123432 (rank : 203)
Query Neighborhood Hits	245	Target Neighborhood Hits	258	Shared Neighborhood Hits	96
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SYJ2B_HUMAN
θ value	0.0431538 (rank : 96)	NC score	0.321192 (rank : 90)
Query Neighborhood Hits	245	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

LIN7B_HUMAN
θ value	0.0563607 (rank : 97)	NC score	0.355016 (rank : 65)
Query Neighborhood Hits	245	Target Neighborhood Hits	200	Shared Neighborhood Hits	106
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

MAST1_HUMAN
θ value	0.0563607 (rank : 98)	NC score	0.047903 (rank : 282)
Query Neighborhood Hits	245	Target Neighborhood Hits	1146	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PDZD3_HUMAN
θ value	0.0563607 (rank : 99)	NC score	0.319551 (rank : 94)
Query Neighborhood Hits	245	Target Neighborhood Hits	180	Shared Neighborhood Hits	104
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PRIC1_HUMAN
θ value	0.0563607 (rank : 100)	NC score	0.408340 (rank : 46)
Query Neighborhood Hits	245	Target Neighborhood Hits	187	Shared Neighborhood Hits	106
SwissProt Accessions	Q96MT3, Q71QF8, Q96N00	Gene names	PRICKLE1, RILP
Domain Architecture	No domain graphic available
Description	Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1).

RPGF2_HUMAN
θ value	0.0563607 (rank : 101)	NC score	0.192041 (rank : 180)
Query Neighborhood Hits	245	Target Neighborhood Hits	242	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

CF049_HUMAN
θ value	0.0736092 (rank : 102)	NC score	0.409302 (rank : 45)
Query Neighborhood Hits	245	Target Neighborhood Hits	123	Shared Neighborhood Hits	97
SwissProt Accessions	Q2TBC4, Q5T3D4, Q9NSV1	Gene names	C6orf49
Domain Architecture	No domain graphic available
Description	Protein C6orf49.

CSRP2_HUMAN
θ value	0.0736092 (rank : 103)	NC score	0.367371 (rank : 59)
Query Neighborhood Hits	245	Target Neighborhood Hits	150	Shared Neighborhood Hits	109
SwissProt Accessions	Q16527, Q93030	Gene names	CSRP2, LMO5, SMLIM
Domain Architecture
Description	Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (Smooth muscle cell LIM protein) (SmLIM) (LIM-only protein 5).

CSRP2_MOUSE
θ value	0.0736092 (rank : 104)	NC score	0.369781 (rank : 56)
Query Neighborhood Hits	245	Target Neighborhood Hits	152	Shared Neighborhood Hits	109
SwissProt Accessions	P97314, Q9CZG5	Gene names	Csrp2, Dlp1
Domain Architecture
Description	Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (Double LIM protein 1) (DLP-1).

FHL3_HUMAN
θ value	0.0736092 (rank : 105)	NC score	0.423216 (rank : 40)
Query Neighborhood Hits	245	Target Neighborhood Hits	354	Shared Neighborhood Hits	113
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

FHL3_MOUSE
θ value	0.0736092 (rank : 106)	NC score	0.415001 (rank : 44)
Query Neighborhood Hits	245	Target Neighborhood Hits	424	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

LHX8_MOUSE
θ value	0.0736092 (rank : 107)	NC score	0.282650 (rank : 134)
Query Neighborhood Hits	245	Target Neighborhood Hits	406	Shared Neighborhood Hits	96
SwissProt Accessions	O35652, O70163, O88707	Gene names	Lhx8, Lhx7
Domain Architecture
Description	LIM/homeobox protein Lhx8 (LIM homeodomain Lhx7) (L3).

LIN7B_MOUSE
θ value	0.0736092 (rank : 108)	NC score	0.350570 (rank : 70)
Query Neighborhood Hits	245	Target Neighborhood Hits	200	Shared Neighborhood Hits	106
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LMO6_MOUSE
θ value	0.0736092 (rank : 109)	NC score	0.397837 (rank : 47)
Query Neighborhood Hits	245	Target Neighborhood Hits	277	Shared Neighborhood Hits	107
SwissProt Accessions	Q80VL3, Q8CAY9	Gene names	Lmo6
Domain Architecture	No domain graphic available
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

LNX2_HUMAN
θ value	0.0736092 (rank : 110)	NC score	0.239834 (rank : 158)
Query Neighborhood Hits	245	Target Neighborhood Hits	389	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PTN13_HUMAN
θ value	0.0736092 (rank : 111)	NC score	0.146280 (rank : 194)
Query Neighborhood Hits	245	Target Neighborhood Hits	471	Shared Neighborhood Hits	104
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

DLG1_MOUSE
θ value	0.0961366 (rank : 112)	NC score	0.206180 (rank : 172)
Query Neighborhood Hits	245	Target Neighborhood Hits	285	Shared Neighborhood Hits	97
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

FHL1_HUMAN
θ value	0.0961366 (rank : 113)	NC score	0.389749 (rank : 51)
Query Neighborhood Hits	245	Target Neighborhood Hits	436	Shared Neighborhood Hits	117
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

GOPC_HUMAN
θ value	0.0961366 (rank : 114)	NC score	0.295024 (rank : 120)
Query Neighborhood Hits	245	Target Neighborhood Hits	377	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

LMO4_HUMAN
θ value	0.0961366 (rank : 115)	NC score	0.339056 (rank : 78)
Query Neighborhood Hits	245	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	P61968, O00158, O88894	Gene names	LMO4
Domain Architecture
Description	LIM domain transcription factor LMO4 (LIM domain only protein 4) (LMO- 4) (Breast tumor autoantigen).

LMO4_MOUSE
θ value	0.0961366 (rank : 116)	NC score	0.339056 (rank : 79)
Query Neighborhood Hits	245	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	P61969, O00158, O88894	Gene names	Lmo4
Domain Architecture
Description	LIM domain transcription factor LMO4 (LIM domain only protein 4) (LMO- 4) (Breast tumor autoantigen).

LMO6_HUMAN
θ value	0.0961366 (rank : 117)	NC score	0.390688 (rank : 50)
Query Neighborhood Hits	245	Target Neighborhood Hits	337	Shared Neighborhood Hits	111
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

RHPN1_HUMAN
θ value	0.0961366 (rank : 118)	NC score	0.262107 (rank : 152)
Query Neighborhood Hits	245	Target Neighborhood Hits	158	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
θ value	0.0961366 (rank : 119)	NC score	0.264371 (rank : 148)
Query Neighborhood Hits	245	Target Neighborhood Hits	154	Shared Neighborhood Hits	101
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SNTG2_MOUSE
θ value	0.0961366 (rank : 120)	NC score	0.292479 (rank : 121)
Query Neighborhood Hits	245	Target Neighborhood Hits	176	Shared Neighborhood Hits	105
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

CSRP3_HUMAN
θ value	0.125558 (rank : 121)	NC score	0.353427 (rank : 67)
Query Neighborhood Hits	245	Target Neighborhood Hits	150	Shared Neighborhood Hits	108
SwissProt Accessions	P50461, Q9P131	Gene names	CSRP3, CLP, MLP
Domain Architecture
Description	Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein).

CSRP3_MOUSE
θ value	0.125558 (rank : 122)	NC score	0.356163 (rank : 64)
Query Neighborhood Hits	245	Target Neighborhood Hits	146	Shared Neighborhood Hits	108
SwissProt Accessions	P50462	Gene names	Csrp3, Clp, Mlp
Domain Architecture
Description	Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein).

DLG1_HUMAN
θ value	0.125558 (rank : 123)	NC score	0.217944 (rank : 167)
Query Neighborhood Hits	245	Target Neighborhood Hits	290	Shared Neighborhood Hits	98
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

FHL5_HUMAN
θ value	0.125558 (rank : 124)	NC score	0.378042 (rank : 54)
Query Neighborhood Hits	245	Target Neighborhood Hits	523	Shared Neighborhood Hits	117
SwissProt Accessions	Q5TD97, Q5TD98, Q8WW21, Q9NQU2	Gene names	FHL5, ACT
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

GOPC_MOUSE
θ value	0.125558 (rank : 125)	NC score	0.298694 (rank : 114)
Query Neighborhood Hits	245	Target Neighborhood Hits	323	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

INADL_HUMAN
θ value	0.125558 (rank : 126)	NC score	0.250852 (rank : 156)
Query Neighborhood Hits	245	Target Neighborhood Hits	260	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

INADL_MOUSE
θ value	0.125558 (rank : 127)	NC score	0.262534 (rank : 150)
Query Neighborhood Hits	245	Target Neighborhood Hits	290	Shared Neighborhood Hits	110
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

ISL1_HUMAN
θ value	0.125558 (rank : 128)	NC score	0.290296 (rank : 123)
Query Neighborhood Hits	245	Target Neighborhood Hits	421	Shared Neighborhood Hits	97
SwissProt Accessions	P61371, P20663, P47894	Gene names	ISL1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

ISL1_MOUSE
θ value	0.125558 (rank : 129)	NC score	0.290296 (rank : 124)
Query Neighborhood Hits	245	Target Neighborhood Hits	421	Shared Neighborhood Hits	97
SwissProt Accessions	P61372, P20663, P47894, Q812D8	Gene names	Isl1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

LHX61_HUMAN
θ value	0.125558 (rank : 130)	NC score	0.286509 (rank : 128)
Query Neighborhood Hits	245	Target Neighborhood Hits	412	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPM6, Q5T7S8, Q9NTK3, Q9UPM5	Gene names	LHX6, LHX6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1 (Lhx6).

LHX61_MOUSE
θ value	0.125558 (rank : 131)	NC score	0.296733 (rank : 117)
Query Neighborhood Hits	245	Target Neighborhood Hits	396	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R1R0, Q9R1R1	Gene names	Lhx6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1.

LIN7C_HUMAN
θ value	0.125558 (rank : 132)	NC score	0.345745 (rank : 71)
Query Neighborhood Hits	245	Target Neighborhood Hits	198	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	0.125558 (rank : 133)	NC score	0.345745 (rank : 72)
Query Neighborhood Hits	245	Target Neighborhood Hits	198	Shared Neighborhood Hits	106
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PTN13_MOUSE
θ value	0.125558 (rank : 134)	NC score	0.143936 (rank : 196)
Query Neighborhood Hits	245	Target Neighborhood Hits	426	Shared Neighborhood Hits	106
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

USH1C_HUMAN
θ value	0.125558 (rank : 135)	NC score	0.331848 (rank : 82)
Query Neighborhood Hits	245	Target Neighborhood Hits	327	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.125558 (rank : 136)	NC score	0.311078 (rank : 106)
Query Neighborhood Hits	245	Target Neighborhood Hits	557	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

DLG3_HUMAN
θ value	0.163984 (rank : 137)	NC score	0.213398 (rank : 170)
Query Neighborhood Hits	245	Target Neighborhood Hits	269	Shared Neighborhood Hits	101
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	0.163984 (rank : 138)	NC score	0.213615 (rank : 169)
Query Neighborhood Hits	245	Target Neighborhood Hits	274	Shared Neighborhood Hits	102
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

FHL2_MOUSE
θ value	0.163984 (rank : 139)	NC score	0.339649 (rank : 76)
Query Neighborhood Hits	245	Target Neighborhood Hits	539	Shared Neighborhood Hits	116
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

LNX2_MOUSE
θ value	0.163984 (rank : 140)	NC score	0.236880 (rank : 159)
Query Neighborhood Hits	245	Target Neighborhood Hits	407	Shared Neighborhood Hits	104
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MICA2_MOUSE
θ value	0.163984 (rank : 141)	NC score	0.105173 (rank : 212)
Query Neighborhood Hits	245	Target Neighborhood Hits	144	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BML1, Q3UPU6	Gene names	Mical2
Domain Architecture
Description	Protein MICAL-2.

RGS12_HUMAN
θ value	0.163984 (rank : 142)	NC score	0.162661 (rank : 186)
Query Neighborhood Hits	245	Target Neighborhood Hits	333	Shared Neighborhood Hits	104
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SNTG2_HUMAN
θ value	0.163984 (rank : 143)	NC score	0.305612 (rank : 110)
Query Neighborhood Hits	245	Target Neighborhood Hits	191	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

DLG2_HUMAN
θ value	0.21417 (rank : 144)	NC score	0.196621 (rank : 175)
Query Neighborhood Hits	245	Target Neighborhood Hits	279	Shared Neighborhood Hits	102
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	0.21417 (rank : 145)	NC score	0.196179 (rank : 177)
Query Neighborhood Hits	245	Target Neighborhood Hits	271	Shared Neighborhood Hits	100
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

FHL2_HUMAN
θ value	0.21417 (rank : 146)	NC score	0.345165 (rank : 73)
Query Neighborhood Hits	245	Target Neighborhood Hits	533	Shared Neighborhood Hits	116
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

LAP4_HUMAN
θ value	0.21417 (rank : 147)	NC score	0.180788 (rank : 182)
Query Neighborhood Hits	245	Target Neighborhood Hits	608	Shared Neighborhood Hits	118
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LIMD2_HUMAN
θ value	0.21417 (rank : 148)	NC score	0.307456 (rank : 109)
Query Neighborhood Hits	245	Target Neighborhood Hits	106	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BT23, Q96S91	Gene names	LIMD2
Domain Architecture	No domain graphic available
Description	LIM domain-containing protein 2.

SNTB1_HUMAN
θ value	0.21417 (rank : 149)	NC score	0.290068 (rank : 125)
Query Neighborhood Hits	245	Target Neighborhood Hits	157	Shared Neighborhood Hits	98
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	0.21417 (rank : 150)	NC score	0.288047 (rank : 127)
Query Neighborhood Hits	245	Target Neighborhood Hits	160	Shared Neighborhood Hits	98
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

TMPSD_MOUSE
θ value	0.21417 (rank : 151)	NC score	0.004530 (rank : 318)
Query Neighborhood Hits	245	Target Neighborhood Hits	334	Shared Neighborhood Hits	11
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ZN337_HUMAN
θ value	0.21417 (rank : 152)	NC score	0.009975 (rank : 312)
Query Neighborhood Hits	245	Target Neighborhood Hits	781	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y3M9, Q9Y3Y5	Gene names	ZNF337
Domain Architecture
Description	Zinc finger protein 337.

LAP4_MOUSE
θ value	0.279714 (rank : 153)	NC score	0.169130 (rank : 183)
Query Neighborhood Hits	245	Target Neighborhood Hits	590	Shared Neighborhood Hits	114
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LHX6_MOUSE
θ value	0.279714 (rank : 154)	NC score	0.276838 (rank : 137)
Query Neighborhood Hits	245	Target Neighborhood Hits	399	Shared Neighborhood Hits	98
SwissProt Accessions	O88706	Gene names	Lhx6
Domain Architecture
Description	LIM/homeobox protein Lhx6.

PDZ11_HUMAN
θ value	0.279714 (rank : 155)	NC score	0.344377 (rank : 74)
Query Neighborhood Hits	245	Target Neighborhood Hits	160	Shared Neighborhood Hits	99
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SNTB2_HUMAN
θ value	0.279714 (rank : 156)	NC score	0.298907 (rank : 113)
Query Neighborhood Hits	245	Target Neighborhood Hits	180	Shared Neighborhood Hits	97
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	0.279714 (rank : 157)	NC score	0.297830 (rank : 116)
Query Neighborhood Hits	245	Target Neighborhood Hits	181	Shared Neighborhood Hits	97
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

ZO3_MOUSE
θ value	0.279714 (rank : 158)	NC score	0.219201 (rank : 165)
Query Neighborhood Hits	245	Target Neighborhood Hits	224	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

MTSS1_MOUSE
θ value	0.365318 (rank : 159)	NC score	0.031933 (rank : 294)
Query Neighborhood Hits	245	Target Neighborhood Hits	592	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PTN4_HUMAN
θ value	0.365318 (rank : 160)	NC score	0.107043 (rank : 211)
Query Neighborhood Hits	245	Target Neighborhood Hits	303	Shared Neighborhood Hits	93
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

DLG4_HUMAN
θ value	0.47712 (rank : 161)	NC score	0.220963 (rank : 164)
Query Neighborhood Hits	245	Target Neighborhood Hits	286	Shared Neighborhood Hits	106
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	0.47712 (rank : 162)	NC score	0.221251 (rank : 163)
Query Neighborhood Hits	245	Target Neighborhood Hits	282	Shared Neighborhood Hits	106
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

LIMD2_MOUSE
θ value	0.47712 (rank : 163)	NC score	0.304183 (rank : 111)
Query Neighborhood Hits	245	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BGB5	Gene names	Limd2
Domain Architecture	No domain graphic available
Description	LIM domain-containing protein 2.

LMCD1_HUMAN
θ value	0.47712 (rank : 164)	NC score	0.375200 (rank : 55)
Query Neighborhood Hits	245	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZU5	Gene names	LMCD1
Domain Architecture
Description	LIM and cysteine-rich domains protein 1 (Dyxin).

PDZ11_MOUSE
θ value	0.47712 (rank : 165)	NC score	0.341263 (rank : 75)
Query Neighborhood Hits	245	Target Neighborhood Hits	154	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

RGS3_HUMAN
θ value	0.47712 (rank : 166)	NC score	0.044195 (rank : 285)
Query Neighborhood Hits	245	Target Neighborhood Hits	1375	Shared Neighborhood Hits	74
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CRIP1_HUMAN
θ value	0.62314 (rank : 167)	NC score	0.328821 (rank : 83)
Query Neighborhood Hits	245	Target Neighborhood Hits	113	Shared Neighborhood Hits	100
SwissProt Accessions	P50238, Q13628, Q96J34	Gene names	CRIP1, CRIP
Domain Architecture
Description	Cysteine-rich protein 1 (Cysteine-rich intestinal protein) (CRIP) (Cysteine-rich heart protein) (hCRHP).

CRIP2_HUMAN
θ value	0.62314 (rank : 168)	NC score	0.284877 (rank : 131)
Query Neighborhood Hits	245	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P52943	Gene names	CRIP2, CRP2
Domain Architecture
Description	Cysteine-rich protein 2 (CRP2) (Protein ESP1).

MICA2_HUMAN
θ value	0.62314 (rank : 169)	NC score	0.101187 (rank : 215)
Query Neighborhood Hits	245	Target Neighborhood Hits	174	Shared Neighborhood Hits	80
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

OBSCN_HUMAN
θ value	0.62314 (rank : 170)	NC score	0.003719 (rank : 321)
Query Neighborhood Hits	245	Target Neighborhood Hits	1931	Shared Neighborhood Hits	34
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PRB4S_HUMAN
θ value	0.62314 (rank : 171)	NC score	0.043744 (rank : 286)
Query Neighborhood Hits	245	Target Neighborhood Hits	330	Shared Neighborhood Hits	22
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

TARA_MOUSE
θ value	0.62314 (rank : 172)	NC score	0.019669 (rank : 301)
Query Neighborhood Hits	245	Target Neighborhood Hits	1133	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TX1B3_HUMAN
θ value	0.62314 (rank : 173)	NC score	0.284808 (rank : 132)
Query Neighborhood Hits	245	Target Neighborhood Hits	161	Shared Neighborhood Hits	96
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	0.62314 (rank : 174)	NC score	0.284885 (rank : 130)
Query Neighborhood Hits	245	Target Neighborhood Hits	158	Shared Neighborhood Hits	96
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

GP112_HUMAN
θ value	0.813845 (rank : 175)	NC score	0.010768 (rank : 310)
Query Neighborhood Hits	245	Target Neighborhood Hits	441	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

LIMK2_HUMAN
θ value	0.813845 (rank : 176)	NC score	0.122284 (rank : 204)
Query Neighborhood Hits	245	Target Neighborhood Hits	986	Shared Neighborhood Hits	146
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LIMK2_MOUSE
θ value	1.06291 (rank : 177)	NC score	0.123496 (rank : 202)
Query Neighborhood Hits	245	Target Neighborhood Hits	998	Shared Neighborhood Hits	145
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

PDZD2_HUMAN
θ value	1.06291 (rank : 178)	NC score	0.217316 (rank : 168)
Query Neighborhood Hits	245	Target Neighborhood Hits	772	Shared Neighborhood Hits	118
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

DMRTA_MOUSE
θ value	1.38821 (rank : 179)	NC score	0.024257 (rank : 298)
Query Neighborhood Hits	245	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFG4	Gene names	Dmrta1, Dmrt4
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1 (Doublesex- and mab-3-related transcription factor 4).

GRIP1_MOUSE
θ value	1.38821 (rank : 180)	NC score	0.262859 (rank : 149)
Query Neighborhood Hits	245	Target Neighborhood Hits	241	Shared Neighborhood Hits	111
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

IRS2_MOUSE
θ value	1.38821 (rank : 181)	NC score	0.026445 (rank : 297)
Query Neighborhood Hits	245	Target Neighborhood Hits	248	Shared Neighborhood Hits	21
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

LNX1_MOUSE
θ value	1.38821 (rank : 182)	NC score	0.205800 (rank : 173)
Query Neighborhood Hits	245	Target Neighborhood Hits	377	Shared Neighborhood Hits	100
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LR37A_HUMAN
θ value	1.38821 (rank : 183)	NC score	0.014819 (rank : 305)
Query Neighborhood Hits	245	Target Neighborhood Hits	720	Shared Neighborhood Hits	26
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

PAK4_MOUSE
θ value	1.38821 (rank : 184)	NC score	0.005755 (rank : 314)
Query Neighborhood Hits	245	Target Neighborhood Hits	1098	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

CRIP1_MOUSE
θ value	1.81305 (rank : 185)	NC score	0.319246 (rank : 95)
Query Neighborhood Hits	245	Target Neighborhood Hits	118	Shared Neighborhood Hits	100
SwissProt Accessions	P63254, P04006, Q3THF0	Gene names	Crip1, Crip
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 1 (Cysteine-rich intestinal protein) (CRIP).

MDC1_MOUSE
θ value	1.81305 (rank : 186)	NC score	0.042847 (rank : 287)
Query Neighborhood Hits	245	Target Neighborhood Hits	998	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MICA3_HUMAN
θ value	1.81305 (rank : 187)	NC score	0.102816 (rank : 214)
Query Neighborhood Hits	245	Target Neighborhood Hits	160	Shared Neighborhood Hits	87
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

ULK1_HUMAN
θ value	1.81305 (rank : 188)	NC score	0.004666 (rank : 316)
Query Neighborhood Hits	245	Target Neighborhood Hits	1121	Shared Neighborhood Hits	23
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZN545_MOUSE
θ value	1.81305 (rank : 189)	NC score	0.001128 (rank : 332)
Query Neighborhood Hits	245	Target Neighborhood Hits	739	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P9Y7, Q6ZPG0	Gene names	Znf545, Kiaa1948, Zfp82
Domain Architecture	No domain graphic available
Description	Zinc finger protein 545 (Zinc finger protein 82).

ZNF96_HUMAN
θ value	1.81305 (rank : 190)	NC score	0.010126 (rank : 311)
Query Neighborhood Hits	245	Target Neighborhood Hits	869	Shared Neighborhood Hits	53
SwissProt Accessions	O43309, O43724	Gene names	ZNF96, KIAA0426, ZNF305, ZSCAN12
Domain Architecture
Description	Zinc finger protein 96 (Zinc finger protein 305) (Zinc finger and SCAN domain-containing protein 12).

CCDC3_MOUSE
θ value	2.36792 (rank : 191)	NC score	0.016669 (rank : 302)
Query Neighborhood Hits	245	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

MAML1_MOUSE
θ value	2.36792 (rank : 192)	NC score	0.014850 (rank : 304)
Query Neighborhood Hits	245	Target Neighborhood Hits	279	Shared Neighborhood Hits	9
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PDZD3_MOUSE
θ value	2.36792 (rank : 193)	NC score	0.285175 (rank : 129)
Query Neighborhood Hits	245	Target Neighborhood Hits	171	Shared Neighborhood Hits	103
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PSCBP_MOUSE
θ value	2.36792 (rank : 194)	NC score	0.218432 (rank : 166)
Query Neighborhood Hits	245	Target Neighborhood Hits	118	Shared Neighborhood Hits	97
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

ZN260_MOUSE
θ value	2.36792 (rank : 195)	NC score	0.003708 (rank : 322)
Query Neighborhood Hits	245	Target Neighborhood Hits	765	Shared Neighborhood Hits	31
SwissProt Accessions	Q62513, Q3U170, Q8C2Q6, Q9R2B4	Gene names	Znf260, Zfp260
Domain Architecture	No domain graphic available
Description	Zinc finger protein 260 (Zfp-260).

ZNF25_HUMAN
θ value	2.36792 (rank : 196)	NC score	0.004549 (rank : 317)
Query Neighborhood Hits	245	Target Neighborhood Hits	763	Shared Neighborhood Hits	29
SwissProt Accessions	P17030, Q8IYE3, Q8NDD6, Q96MU2	Gene names	ZNF25, KOX19
Domain Architecture
Description	Zinc finger protein 25 (Zinc finger protein KOX19).

ZNF32_MOUSE
θ value	2.36792 (rank : 197)	NC score	0.003700 (rank : 323)
Query Neighborhood Hits	245	Target Neighborhood Hits	737	Shared Neighborhood Hits	29
SwissProt Accessions	Q80V23, Q3UIS3	Gene names	Znf32, Zfp637
Domain Architecture	No domain graphic available
Description	Zinc finger protein 32 (Zinc finger protein 637).

ZO3_HUMAN
θ value	2.36792 (rank : 198)	NC score	0.194070 (rank : 179)
Query Neighborhood Hits	245	Target Neighborhood Hits	219	Shared Neighborhood Hits	107
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

LHX5_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.274157 (rank : 140)
Query Neighborhood Hits	245	Target Neighborhood Hits	453	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H2C1	Gene names	LHX5
Domain Architecture
Description	LIM/homeobox protein Lhx5.

LHX5_MOUSE
θ value	3.0926 (rank : 200)	NC score	0.275361 (rank : 139)
Query Neighborhood Hits	245	Target Neighborhood Hits	456	Shared Neighborhood Hits	103
SwissProt Accessions	P61375, P50459	Gene names	Lhx5
Domain Architecture
Description	LIM/homeobox protein Lhx5.

MAST2_MOUSE
θ value	3.0926 (rank : 201)	NC score	0.041149 (rank : 288)
Query Neighborhood Hits	245	Target Neighborhood Hits	1110	Shared Neighborhood Hits	102
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MTSS1_HUMAN
θ value	3.0926 (rank : 202)	NC score	0.029627 (rank : 296)
Query Neighborhood Hits	245	Target Neighborhood Hits	504	Shared Neighborhood Hits	19
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

RBTN1_HUMAN
θ value	3.0926 (rank : 203)	NC score	0.320591 (rank : 92)
Query Neighborhood Hits	245	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	P25800, Q4VBC5	Gene names	LMO1, RBTN1, RHOM1, TTG1
Domain Architecture
Description	Rhombotin-1 (Cysteine-rich protein TTG-1) (T-cell translocation protein 1) (LIM-only protein 1).

RBTN1_MOUSE
θ value	3.0926 (rank : 204)	NC score	0.321112 (rank : 91)
Query Neighborhood Hits	245	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	Q924W9	Gene names	Lmo1, Rbtn1, Rhom1, Ttg1
Domain Architecture	No domain graphic available
Description	Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM-only protein 1).

ZNF32_HUMAN
θ value	3.0926 (rank : 205)	NC score	0.002031 (rank : 328)
Query Neighborhood Hits	245	Target Neighborhood Hits	735	Shared Neighborhood Hits	24
SwissProt Accessions	P17041, Q92951	Gene names	ZNF32, KOX30
Domain Architecture	No domain graphic available
Description	Zinc finger protein 32 (Zinc finger protein KOX30) (C2H2-546).

ARHGB_HUMAN
θ value	4.03905 (rank : 206)	NC score	0.141953 (rank : 197)
Query Neighborhood Hits	245	Target Neighborhood Hits	375	Shared Neighborhood Hits	107
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

AZI1_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.002835 (rank : 327)
Query Neighborhood Hits	245	Target Neighborhood Hits	1000	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

GRIP1_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.258777 (rank : 154)
Query Neighborhood Hits	245	Target Neighborhood Hits	231	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MAST2_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.040876 (rank : 290)
Query Neighborhood Hits	245	Target Neighborhood Hits	1189	Shared Neighborhood Hits	100
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MILK2_HUMAN
θ value	4.03905 (rank : 210)	NC score	0.079919 (rank : 239)
Query Neighborhood Hits	245	Target Neighborhood Hits	457	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MLL3_MOUSE
θ value	4.03905 (rank : 211)	NC score	0.041028 (rank : 289)
Query Neighborhood Hits	245	Target Neighborhood Hits	1399	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ZN584_HUMAN
θ value	4.03905 (rank : 212)	NC score	0.004068 (rank : 319)
Query Neighborhood Hits	245	Target Neighborhood Hits	741	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IVC4	Gene names	ZNF584
Domain Architecture	No domain graphic available
Description	Zinc finger protein 584.

BSN_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.031091 (rank : 295)
Query Neighborhood Hits	245	Target Neighborhood Hits	2057	Shared Neighborhood Hits	59
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

COIA1_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.003949 (rank : 320)
Query Neighborhood Hits	245	Target Neighborhood Hits	481	Shared Neighborhood Hits	16
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

ENAH_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.007829 (rank : 313)
Query Neighborhood Hits	245	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

JADE2_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.013542 (rank : 308)
Query Neighborhood Hits	245	Target Neighborhood Hits	560	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LHX1_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.268960 (rank : 145)
Query Neighborhood Hits	245	Target Neighborhood Hits	453	Shared Neighborhood Hits	102
SwissProt Accessions	P48742, Q3MIW0	Gene names	LHX1, LIM1
Domain Architecture
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

LHX1_MOUSE
θ value	5.27518 (rank : 218)	NC score	0.268859 (rank : 146)
Query Neighborhood Hits	245	Target Neighborhood Hits	453	Shared Neighborhood Hits	102
SwissProt Accessions	P63006, P36199	Gene names	Lhx1, Lim-1, Lim1
Domain Architecture	No domain graphic available
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

LMO3_HUMAN
θ value	5.27518 (rank : 219)	NC score	0.317250 (rank : 99)
Query Neighborhood Hits	245	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	Q8TAP4, Q8N974, Q9UDD5	Gene names	LMO3, RBTN3, RHOM3
Domain Architecture
Description	LIM-only protein 3 (Neuronal-specific transcription factor DAT1) (Rhombotin-3).

LMO3_MOUSE
θ value	5.27518 (rank : 220)	NC score	0.317250 (rank : 100)
Query Neighborhood Hits	245	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BZL8	Gene names	Lmo3
Domain Architecture
Description	LIM-only protein 3 (Neuronal-specific transcription factor DAT1).

LNX1_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.203019 (rank : 174)
Query Neighborhood Hits	245	Target Neighborhood Hits	379	Shared Neighborhood Hits	96
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAST3_HUMAN
θ value	5.27518 (rank : 222)	NC score	0.037536 (rank : 291)
Query Neighborhood Hits	245	Target Neighborhood Hits	1128	Shared Neighborhood Hits	92
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MAST4_HUMAN
θ value	5.27518 (rank : 223)	NC score	0.044290 (rank : 284)
Query Neighborhood Hits	245	Target Neighborhood Hits	1804	Shared Neighborhood Hits	114
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MUC1_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.047282 (rank : 283)
Query Neighborhood Hits	245	Target Neighborhood Hits	975	Shared Neighborhood Hits	47
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PWWP2_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.015143 (rank : 303)
Query Neighborhood Hits	245	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

RBTN2_HUMAN
θ value	5.27518 (rank : 226)	NC score	0.327494 (rank : 87)
Query Neighborhood Hits	245	Target Neighborhood Hits	114	Shared Neighborhood Hits	103
SwissProt Accessions	P25791, Q9HD58	Gene names	LMO2, RBTN2, RHOM2, TTG2
Domain Architecture
Description	Rhombotin-2 (Cysteine-rich protein TTG-2) (T-cell translocation protein 2) (LIM-only protein 2).

RBTN2_MOUSE
θ value	5.27518 (rank : 227)	NC score	0.327504 (rank : 86)
Query Neighborhood Hits	245	Target Neighborhood Hits	114	Shared Neighborhood Hits	103
SwissProt Accessions	P25801	Gene names	Lmo2, Rbtn-2, Rbtn2, Rhom-2
Domain Architecture
Description	Rhombotin-2 (Cysteine-rich protein TTG-2) (T-cell translocation protein 2) (LIM-only protein 2).

ZN230_HUMAN
θ value	5.27518 (rank : 228)	NC score	0.003207 (rank : 325)
Query Neighborhood Hits	245	Target Neighborhood Hits	750	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UIE0, O15322, Q9P1U6	Gene names	ZNF230, FDZF2
Domain Architecture
Description	Zinc finger protein 230 (Zinc finger protein FDZF2).

ADA12_MOUSE
θ value	6.88961 (rank : 229)	NC score	0.003143 (rank : 326)
Query Neighborhood Hits	245	Target Neighborhood Hits	474	Shared Neighborhood Hits	14
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_MOUSE
θ value	6.88961 (rank : 230)	NC score	0.001241 (rank : 331)
Query Neighborhood Hits	245	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ENAH_MOUSE
θ value	6.88961 (rank : 231)	NC score	0.021705 (rank : 300)
Query Neighborhood Hits	245	Target Neighborhood Hits	919	Shared Neighborhood Hits	36
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ETV5_MOUSE
θ value	6.88961 (rank : 232)	NC score	0.004999 (rank : 315)
Query Neighborhood Hits	245	Target Neighborhood Hits	328	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

F125B_HUMAN
θ value	6.88961 (rank : 233)	NC score	0.013578 (rank : 307)
Query Neighborhood Hits	245	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7P6, Q8N6S7	Gene names	FAM125B, C9orf28
Domain Architecture	No domain graphic available
Description	Protein FAM125B.

GRIP2_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.251203 (rank : 155)
Query Neighborhood Hits	245	Target Neighborhood Hits	256	Shared Neighborhood Hits	112
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

LMX1B_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.273379 (rank : 142)
Query Neighborhood Hits	245	Target Neighborhood Hits	404	Shared Neighborhood Hits	96
SwissProt Accessions	O60663, O75463	Gene names	LMX1B
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

LMX1B_MOUSE
θ value	6.88961 (rank : 236)	NC score	0.274107 (rank : 141)
Query Neighborhood Hits	245	Target Neighborhood Hits	394	Shared Neighborhood Hits	96
SwissProt Accessions	O88609	Gene names	Lmx1b
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

PSCBP_HUMAN
θ value	6.88961 (rank : 237)	NC score	0.194170 (rank : 178)
Query Neighborhood Hits	245	Target Neighborhood Hits	123	Shared Neighborhood Hits	88
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

CRTC1_HUMAN
θ value	8.99809 (rank : 238)	NC score	0.014093 (rank : 306)
Query Neighborhood Hits	245	Target Neighborhood Hits	319	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

DVL2_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.075660 (rank : 252)
Query Neighborhood Hits	245	Target Neighborhood Hits	223	Shared Neighborhood Hits	65
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

F125B_MOUSE
θ value	8.99809 (rank : 240)	NC score	0.012624 (rank : 309)
Query Neighborhood Hits	245	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q6KAU4, Q6PB42	Gene names	Fam125b
Domain Architecture	No domain graphic available
Description	Protein FAM125B.

GLI4_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.003262 (rank : 324)
Query Neighborhood Hits	245	Target Neighborhood Hits	735	Shared Neighborhood Hits	29
SwissProt Accessions	P10075, Q96CK9	Gene names	GLI4, HKR4
Domain Architecture
Description	Zinc finger protein GLI4 (Krueppel-related zinc finger protein 4) (Protein HKR4).

MILK1_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.076913 (rank : 248)
Query Neighborhood Hits	245	Target Neighborhood Hits	788	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MY18A_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.022112 (rank : 299)
Query Neighborhood Hits	245	Target Neighborhood Hits	1989	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TMPSD_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.001760 (rank : 329)
Query Neighborhood Hits	245	Target Neighborhood Hits	333	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ZN545_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.001433 (rank : 330)
Query Neighborhood Hits	245	Target Neighborhood Hits	744	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N141, Q8NC63, Q8TF53	Gene names	ZNF545, KIAA1948
Domain Architecture	No domain graphic available
Description	Zinc finger protein 545.

AFAD_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.108060 (rank : 210)
Query Neighborhood Hits	245	Target Neighborhood Hits	689	Shared Neighborhood Hits	83
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

APBA1_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.088471 (rank : 225)
Query Neighborhood Hits	245	Target Neighborhood Hits	325	Shared Neighborhood Hits	78
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

APBA2_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.091877 (rank : 221)
Query Neighborhood Hits	245	Target Neighborhood Hits	220	Shared Neighborhood Hits	80
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.087263 (rank : 229)
Query Neighborhood Hits	245	Target Neighborhood Hits	219	Shared Neighborhood Hits	79
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.086462 (rank : 230)
Query Neighborhood Hits	245	Target Neighborhood Hits	201	Shared Neighborhood Hits	76
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA3_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.081129 (rank : 238)
Query Neighborhood Hits	245	Target Neighborhood Hits	174	Shared Neighborhood Hits	74
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHGC_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.112039 (rank : 207)
Query Neighborhood Hits	245	Target Neighborhood Hits	351	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.111147 (rank : 208)
Query Neighborhood Hits	245	Target Neighborhood Hits	344	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CRIP2_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.250566 (rank : 157)
Query Neighborhood Hits	245	Target Neighborhood Hits	98	Shared Neighborhood Hits	90
SwissProt Accessions	Q9DCT8	Gene names	Crip2, Crp2, Hlp
Domain Architecture
Description	Cysteine-rich protein 2 (CRP2) (Heart LIM protein).

CRIP3_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.261288 (rank : 153)
Query Neighborhood Hits	245	Target Neighborhood Hits	104	Shared Neighborhood Hits	91
SwissProt Accessions	Q6Q6R5, Q5T043, Q6Q6R4, Q6Q6R6, Q6Q6R7	Gene names	CRIP3
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Chromosome 6 LIM-only protein) (h6LIMo).

CRIP3_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.196548 (rank : 176)
Query Neighborhood Hits	245	Target Neighborhood Hits	94	Shared Neighborhood Hits	80
SwissProt Accessions	Q6Q6R3, Q91V23, Q91V60	Gene names	Crip3, Tlp
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Thymus LIM protein) (m17TLP).

DEMA_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.090912 (rank : 222)
Query Neighborhood Hits	245	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q08495, Q13215, Q9BRE3	Gene names	EPB49, DMT
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

DEMA_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.090201 (rank : 223)
Query Neighborhood Hits	245	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

DVL1L_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.071062 (rank : 262)
Query Neighborhood Hits	245	Target Neighborhood Hits	146	Shared Neighborhood Hits	63
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.075569 (rank : 253)
Query Neighborhood Hits	245	Target Neighborhood Hits	158	Shared Neighborhood Hits	65
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.073638 (rank : 258)
Query Neighborhood Hits	245	Target Neighborhood Hits	146	Shared Neighborhood Hits	63
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL2_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.071758 (rank : 260)
Query Neighborhood Hits	245	Target Neighborhood Hits	233	Shared Neighborhood Hits	63
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.075050 (rank : 257)
Query Neighborhood Hits	245	Target Neighborhood Hits	194	Shared Neighborhood Hits	60
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.076245 (rank : 251)
Query Neighborhood Hits	245	Target Neighborhood Hits	198	Shared Neighborhood Hits	63
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

EM55_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.075350 (rank : 254)
Query Neighborhood Hits	245	Target Neighborhood Hits	228	Shared Neighborhood Hits	67
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.072074 (rank : 259)
Query Neighborhood Hits	245	Target Neighborhood Hits	221	Shared Neighborhood Hits	65
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

GIPC1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.056370 (rank : 275)
Query Neighborhood Hits	245	Target Neighborhood Hits	92	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

IL16_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.209475 (rank : 171)
Query Neighborhood Hits	245	Target Neighborhood Hits	207	Shared Neighborhood Hits	86
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IL16_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.191746 (rank : 181)
Query Neighborhood Hits	245	Target Neighborhood Hits	189	Shared Neighborhood Hits	82
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

K1849_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.121150 (rank : 205)
Query Neighborhood Hits	245	Target Neighborhood Hits	220	Shared Neighborhood Hits	81
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.120215 (rank : 206)
Query Neighborhood Hits	245	Target Neighborhood Hits	335	Shared Neighborhood Hits	85
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LAP2_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.056102 (rank : 276)
Query Neighborhood Hits	245	Target Neighborhood Hits	499	Shared Neighborhood Hits	70
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.053849 (rank : 278)
Query Neighborhood Hits	245	Target Neighborhood Hits	482	Shared Neighborhood Hits	73
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LMO7_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.084005 (rank : 237)
Query Neighborhood Hits	245	Target Neighborhood Hits	507	Shared Neighborhood Hits	97
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LMX1A_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.272123 (rank : 143)
Query Neighborhood Hits	245	Target Neighborhood Hits	406	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TE12, Q8TE11	Gene names	LMX1A
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

LMX1A_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.275803 (rank : 138)
Query Neighborhood Hits	245	Target Neighborhood Hits	405	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JKU8	Gene names	Lmx1a
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

LRRC7_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.062650 (rank : 266)
Query Neighborhood Hits	245	Target Neighborhood Hits	423	Shared Neighborhood Hits	79
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.062051 (rank : 267)
Query Neighborhood Hits	245	Target Neighborhood Hits	416	Shared Neighborhood Hits	81
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MICA1_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.061374 (rank : 268)
Query Neighborhood Hits	245	Target Neighborhood Hits	279	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MICA1_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.050289 (rank : 280)
Query Neighborhood Hits	245	Target Neighborhood Hits	400	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MICA3_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.052507 (rank : 279)
Query Neighborhood Hits	245	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CJ19, Q80TE8, Q8BXB1	Gene names	Mical3, Kiaa1364
Domain Architecture
Description	Protein MICAL-3.

MILK1_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.056398 (rank : 274)
Query Neighborhood Hits	245	Target Neighborhood Hits	427	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MPP2_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.059177 (rank : 272)
Query Neighborhood Hits	245	Target Neighborhood Hits	173	Shared Neighborhood Hits	57
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.060214 (rank : 271)
Query Neighborhood Hits	245	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP3_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.085358 (rank : 234)
Query Neighborhood Hits	245	Target Neighborhood Hits	171	Shared Neighborhood Hits	68
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.085613 (rank : 232)
Query Neighborhood Hits	245	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.098629 (rank : 219)
Query Neighborhood Hits	245	Target Neighborhood Hits	205	Shared Neighborhood Hits	74
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP4_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.085610 (rank : 233)
Query Neighborhood Hits	245	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP5_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.084807 (rank : 235)
Query Neighborhood Hits	245	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.084510 (rank : 236)
Query Neighborhood Hits	245	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP6_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.058689 (rank : 273)
Query Neighborhood Hits	245	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.061133 (rank : 270)
Query Neighborhood Hits	245	Target Neighborhood Hits	187	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

NEB1_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.076682 (rank : 249)
Query Neighborhood Hits	245	Target Neighborhood Hits	829	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.071297 (rank : 261)
Query Neighborhood Hits	245	Target Neighborhood Hits	883	Shared Neighborhood Hits	64
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.070976 (rank : 263)
Query Neighborhood Hits	245	Target Neighborhood Hits	889	Shared Neighborhood Hits	66
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NOS1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.079866 (rank : 240)
Query Neighborhood Hits	245	Target Neighborhood Hits	218	Shared Neighborhood Hits	82
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS1_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.068045 (rank : 265)
Query Neighborhood Hits	245	Target Neighborhood Hits	155	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PAR3L_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.162043 (rank : 188)
Query Neighborhood Hits	245	Target Neighborhood Hits	297	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PAR6A_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.076605 (rank : 250)
Query Neighborhood Hits	245	Target Neighborhood Hits	119	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.076953 (rank : 247)
Query Neighborhood Hits	245	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6B_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.088057 (rank : 227)
Query Neighborhood Hits	245	Target Neighborhood Hits	126	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.088167 (rank : 226)
Query Neighborhood Hits	245	Target Neighborhood Hits	128	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.089349 (rank : 224)
Query Neighborhood Hits	245	Target Neighborhood Hits	159	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.086285 (rank : 231)
Query Neighborhood Hits	245	Target Neighborhood Hits	121	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PARD3_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.166333 (rank : 185)
Query Neighborhood Hits	245	Target Neighborhood Hits	312	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PARD3_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.167586 (rank : 184)
Query Neighborhood Hits	245	Target Neighborhood Hits	290	Shared Neighborhood Hits	87
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PCLO_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.061230 (rank : 269)
Query Neighborhood Hits	245	Target Neighborhood Hits	2275	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDZK4_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.078412 (rank : 243)
Query Neighborhood Hits	245	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.078735 (rank : 242)
Query Neighborhood Hits	245	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PICK1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.099840 (rank : 217)
Query Neighborhood Hits	245	Target Neighborhood Hits	132	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.099656 (rank : 218)
Query Neighborhood Hits	245	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PZRN3_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.131339 (rank : 200)
Query Neighborhood Hits	245	Target Neighborhood Hits	461	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.133534 (rank : 199)
Query Neighborhood Hits	245	Target Neighborhood Hits	447	Shared Neighborhood Hits	87
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.137825 (rank : 198)
Query Neighborhood Hits	245	Target Neighborhood Hits	438	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RHPN2_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.068131 (rank : 264)
Query Neighborhood Hits	245	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RIMS1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.055616 (rank : 277)
Query Neighborhood Hits	245	Target Neighborhood Hits	437	Shared Neighborhood Hits	77
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SDCB1_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.100728 (rank : 216)
Query Neighborhood Hits	245	Target Neighborhood Hits	150	Shared Neighborhood Hits	83
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.105008 (rank : 213)
Query Neighborhood Hits	245	Target Neighborhood Hits	144	Shared Neighborhood Hits	83
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB2_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.095910 (rank : 220)
Query Neighborhood Hits	245	Target Neighborhood Hits	121	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.087605 (rank : 228)
Query Neighborhood Hits	245	Target Neighborhood Hits	118	Shared Neighborhood Hits	67
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SHAN1_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.077233 (rank : 246)
Query Neighborhood Hits	245	Target Neighborhood Hits	1041	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.123716 (rank : 201)
Query Neighborhood Hits	245	Target Neighborhood Hits	346	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.109004 (rank : 209)
Query Neighborhood Hits	245	Target Neighborhood Hits	446	Shared Neighborhood Hits	92
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

STXB4_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.077802 (rank : 244)
Query Neighborhood Hits	245	Target Neighborhood Hits	616	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.075205 (rank : 256)
Query Neighborhood Hits	245	Target Neighborhood Hits	629	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYNPO_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.077463 (rank : 245)
Query Neighborhood Hits	245	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SYNPO_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.079807 (rank : 241)
Query Neighborhood Hits	245	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

ZN185_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.075326 (rank : 255)
Query Neighborhood Hits	245	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

ZO1_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.162482 (rank : 187)
Query Neighborhood Hits	245	Target Neighborhood Hits	474	Shared Neighborhood Hits	107
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.160367 (rank : 189)
Query Neighborhood Hits	245	Target Neighborhood Hits	453	Shared Neighborhood Hits	106
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.158174 (rank : 190)
Query Neighborhood Hits	245	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.149364 (rank : 192)
Query Neighborhood Hits	245	Target Neighborhood Hits	296	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

Hits sorted by NC score

PDLI4_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.01004e-176 (rank : 1)
Query Neighborhood Hits	245	Target Neighborhood Hits	245	Shared Neighborhood Hits	245
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
NC score	0.990878 (rank : 2)	θ value	2.11095e-166 (rank : 2)
Query Neighborhood Hits	245	Target Neighborhood Hits	233	Shared Neighborhood Hits	210
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI3_HUMAN
NC score	0.952019 (rank : 3)	θ value	1.11475e-66 (rank : 6)
Query Neighborhood Hits	245	Target Neighborhood Hits	199	Shared Neighborhood Hits	182
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_MOUSE
NC score	0.951957 (rank : 4)	θ value	1.00825e-67 (rank : 5)
Query Neighborhood Hits	245	Target Neighborhood Hits	197	Shared Neighborhood Hits	179
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI1_HUMAN
NC score	0.937006 (rank : 5)	θ value	1.66191e-70 (rank : 3)
Query Neighborhood Hits	245	Target Neighborhood Hits	242	Shared Neighborhood Hits	166
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
NC score	0.931349 (rank : 6)	θ value	4.09345e-69 (rank : 4)
Query Neighborhood Hits	245	Target Neighborhood Hits	213	Shared Neighborhood Hits	157
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI2_MOUSE
NC score	0.871008 (rank : 7)	θ value	1.24399e-33 (rank : 8)
Query Neighborhood Hits	245	Target Neighborhood Hits	220	Shared Neighborhood Hits	162
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDLI2_HUMAN
NC score	0.867712 (rank : 8)	θ value	4.13158e-37 (rank : 7)
Query Neighborhood Hits	245	Target Neighborhood Hits	245	Shared Neighborhood Hits	164
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI7_MOUSE
NC score	0.731814 (rank : 9)	θ value	2.5182e-18 (rank : 13)
Query Neighborhood Hits	245	Target Neighborhood Hits	279	Shared Neighborhood Hits	186
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDLI7_HUMAN
NC score	0.725064 (rank : 10)	θ value	7.56453e-23 (rank : 9)
Query Neighborhood Hits	245	Target Neighborhood Hits	547	Shared Neighborhood Hits	196
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LDB3_MOUSE
NC score	0.721389 (rank : 11)	θ value	1.42661e-21 (rank : 10)
Query Neighborhood Hits	245	Target Neighborhood Hits	510	Shared Neighborhood Hits	189
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PDLI5_HUMAN
NC score	0.719995 (rank : 12)	θ value	2.5182e-18 (rank : 12)
Query Neighborhood Hits	245	Target Neighborhood Hits	322	Shared Neighborhood Hits	189
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

LDB3_HUMAN
NC score	0.718227 (rank : 13)	θ value	3.17815e-21 (rank : 11)
Query Neighborhood Hits	245	Target Neighborhood Hits	497	Shared Neighborhood Hits	192
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

PDLI5_MOUSE
NC score	0.717945 (rank : 14)	θ value	2.13179e-17 (rank : 14)
Query Neighborhood Hits	245	Target Neighborhood Hits	287	Shared Neighborhood Hits	190
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SYNP2_MOUSE
NC score	0.520350 (rank : 15)	θ value	9.59137e-10 (rank : 15)
Query Neighborhood Hits	245	Target Neighborhood Hits	252	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

LPXN_HUMAN
NC score	0.516324 (rank : 16)	θ value	7.59969e-07 (rank : 19)
Query Neighborhood Hits	245	Target Neighborhood Hits	159	Shared Neighborhood Hits	108
SwissProt Accessions	O60711	Gene names	LPXN, LDLP
Domain Architecture
Description	Leupaxin.

SYP2L_HUMAN
NC score	0.515584 (rank : 17)	θ value	6.21693e-09 (rank : 17)
Query Neighborhood Hits	245	Target Neighborhood Hits	400	Shared Neighborhood Hits	111
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

SYNP2_HUMAN
NC score	0.509066 (rank : 18)	θ value	4.76016e-09 (rank : 16)
Query Neighborhood Hits	245	Target Neighborhood Hits	323	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

LPXN_MOUSE
NC score	0.503394 (rank : 19)	θ value	2.88788e-06 (rank : 21)
Query Neighborhood Hits	245	Target Neighborhood Hits	227	Shared Neighborhood Hits	109
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

PAXI_HUMAN
NC score	0.499797 (rank : 20)	θ value	2.44474e-05 (rank : 24)
Query Neighborhood Hits	245	Target Neighborhood Hits	173	Shared Neighborhood Hits	110
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

PAXI_MOUSE
NC score	0.499779 (rank : 21)	θ value	2.44474e-05 (rank : 25)
Query Neighborhood Hits	245	Target Neighborhood Hits	176	Shared Neighborhood Hits	109
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

PINC_HUMAN
NC score	0.490808 (rank : 22)	θ value	0.00102713 (rank : 45)
Query Neighborhood Hits	245	Target Neighborhood Hits	231	Shared Neighborhood Hits	109
SwissProt Accessions	P48059, Q53TE0, Q9BS44	Gene names	LIMS1
Domain Architecture
Description	Protein PINCH (Particularly interesting new Cys-His protein) (LIM and senescent cell antigen-like domains 1) (NY-REN-48 antigen).

LIMD1_MOUSE
NC score	0.476848 (rank : 23)	θ value	5.44631e-05 (rank : 27)
Query Neighborhood Hits	245	Target Neighborhood Hits	291	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

LIMD1_HUMAN
NC score	0.472854 (rank : 24)	θ value	0.00020696 (rank : 36)
Query Neighborhood Hits	245	Target Neighborhood Hits	201	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

SYP2L_MOUSE
NC score	0.470439 (rank : 25)	θ value	9.92553e-07 (rank : 20)
Query Neighborhood Hits	245	Target Neighborhood Hits	289	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TRIP6_HUMAN
NC score	0.459400 (rank : 26)	θ value	0.000121331 (rank : 33)
Query Neighborhood Hits	245	Target Neighborhood Hits	228	Shared Neighborhood Hits	101
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

ABLM3_HUMAN
NC score	0.457107 (rank : 27)	θ value	1.43324e-05 (rank : 22)
Query Neighborhood Hits	245	Target Neighborhood Hits	293	Shared Neighborhood Hits	119
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM3_MOUSE
NC score	0.456877 (rank : 28)	θ value	2.44474e-05 (rank : 23)
Query Neighborhood Hits	245	Target Neighborhood Hits	294	Shared Neighborhood Hits	120
SwissProt Accessions	Q69ZX8, Q52KR1, Q6PAI7	Gene names	Ablim3, Kiaa0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

ABLM2_HUMAN
NC score	0.448111 (rank : 29)	θ value	0.000121331 (rank : 30)
Query Neighborhood Hits	245	Target Neighborhood Hits	317	Shared Neighborhood Hits	112
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

LPP_MOUSE
NC score	0.443546 (rank : 30)	θ value	5.44631e-05 (rank : 28)
Query Neighborhood Hits	245	Target Neighborhood Hits	247	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

ABLM2_MOUSE
NC score	0.442219 (rank : 31)	θ value	0.00102713 (rank : 43)
Query Neighborhood Hits	245	Target Neighborhood Hits	306	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BL65, Q6H8P8, Q80WK6, Q8BUT1, Q8BXI7	Gene names	Ablim2
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

FBLI1_HUMAN
NC score	0.442119 (rank : 32)	θ value	0.00665767 (rank : 59)
Query Neighborhood Hits	245	Target Neighborhood Hits	200	Shared Neighborhood Hits	106
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

FBLI1_MOUSE
NC score	0.438173 (rank : 33)	θ value	0.0431538 (rank : 92)
Query Neighborhood Hits	245	Target Neighborhood Hits	228	Shared Neighborhood Hits	113
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

APXL_HUMAN
NC score	0.437771 (rank : 34)	θ value	5.81887e-07 (rank : 18)
Query Neighborhood Hits	245	Target Neighborhood Hits	553	Shared Neighborhood Hits	88
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

TES_MOUSE
NC score	0.435952 (rank : 35)	θ value	0.00020696 (rank : 37)
Query Neighborhood Hits	245	Target Neighborhood Hits	171	Shared Neighborhood Hits	106
SwissProt Accessions	P47226	Gene names	Tes
Domain Architecture
Description	Testin (TES1/TES2).

TES_HUMAN
NC score	0.430176 (rank : 36)	θ value	0.000270298 (rank : 40)
Query Neighborhood Hits	245	Target Neighborhood Hits	131	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UGI8, Q9GZQ1, Q9HAJ9	Gene names	TES
Domain Architecture
Description	Testin (TESS).

ABLM1_MOUSE
NC score	0.427326 (rank : 37)	θ value	0.00102713 (rank : 42)
Query Neighborhood Hits	245	Target Neighborhood Hits	356	Shared Neighborhood Hits	117
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

ABLM1_HUMAN
NC score	0.426093 (rank : 38)	θ value	0.000602161 (rank : 41)
Query Neighborhood Hits	245	Target Neighborhood Hits	387	Shared Neighborhood Hits	119
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

PRIC2_MOUSE
NC score	0.423441 (rank : 39)	θ value	0.00298849 (rank : 52)
Query Neighborhood Hits	245	Target Neighborhood Hits	185	Shared Neighborhood Hits	108
SwissProt Accessions	Q80Y24	Gene names	Prickle2
Domain Architecture	No domain graphic available
Description	Prickle-like protein 2.

FHL3_HUMAN
NC score	0.423216 (rank : 40)	θ value	0.0736092 (rank : 105)
Query Neighborhood Hits	245	Target Neighborhood Hits	354	Shared Neighborhood Hits	113
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

ZYX_HUMAN
NC score	0.422891 (rank : 41)	θ value	0.0252991 (rank : 86)
Query Neighborhood Hits	245	Target Neighborhood Hits	387	Shared Neighborhood Hits	121
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

PRIC2_HUMAN
NC score	0.422759 (rank : 42)	θ value	0.00390308 (rank : 56)
Query Neighborhood Hits	245	Target Neighborhood Hits	197	Shared Neighborhood Hits	108
SwissProt Accessions	Q7Z3G6	Gene names	PRICKLE2
Domain Architecture	No domain graphic available
Description	Prickle-like protein 2.

ZYX_MOUSE
NC score	0.422331 (rank : 43)	θ value	0.0113563 (rank : 71)
Query Neighborhood Hits	245	Target Neighborhood Hits	347	Shared Neighborhood Hits	116
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

FHL3_MOUSE
NC score	0.415001 (rank : 44)	θ value	0.0736092 (rank : 106)
Query Neighborhood Hits	245	Target Neighborhood Hits	424	Shared Neighborhood Hits	118
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

CF049_HUMAN
NC score	0.409302 (rank : 45)	θ value	0.0736092 (rank : 102)
Query Neighborhood Hits	245	Target Neighborhood Hits	123	Shared Neighborhood Hits	97
SwissProt Accessions	Q2TBC4, Q5T3D4, Q9NSV1	Gene names	C6orf49
Domain Architecture	No domain graphic available
Description	Protein C6orf49.

PRIC1_HUMAN
NC score	0.408340 (rank : 46)	θ value	0.0563607 (rank : 100)
Query Neighborhood Hits	245	Target Neighborhood Hits	187	Shared Neighborhood Hits	106
SwissProt Accessions	Q96MT3, Q71QF8, Q96N00	Gene names	PRICKLE1, RILP
Domain Architecture	No domain graphic available
Description	Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1).

LMO6_MOUSE
NC score	0.397837 (rank : 47)	θ value	0.0736092 (rank : 109)
Query Neighborhood Hits	245	Target Neighborhood Hits	277	Shared Neighborhood Hits	107
SwissProt Accessions	Q80VL3, Q8CAY9	Gene names	Lmo6
Domain Architecture	No domain graphic available
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

LPP_HUMAN
NC score	0.396816 (rank : 48)	θ value	0.000121331 (rank : 32)
Query Neighborhood Hits	245	Target Neighborhood Hits	775	Shared Neighborhood Hits	131
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

FHL1_MOUSE
NC score	0.395814 (rank : 49)	θ value	0.00665767 (rank : 60)
Query Neighborhood Hits	245	Target Neighborhood Hits	462	Shared Neighborhood Hits	119
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

LMO6_HUMAN
NC score	0.390688 (rank : 50)	θ value	0.0961366 (rank : 117)
Query Neighborhood Hits	245	Target Neighborhood Hits	337	Shared Neighborhood Hits	111
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

FHL1_HUMAN
NC score	0.389749 (rank : 51)	θ value	0.0961366 (rank : 113)
Query Neighborhood Hits	245	Target Neighborhood Hits	436	Shared Neighborhood Hits	117
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

FHL5_MOUSE
NC score	0.388421 (rank : 52)	θ value	0.0330416 (rank : 87)
Query Neighborhood Hits	245	Target Neighborhood Hits	463	Shared Neighborhood Hits	114
SwissProt Accessions	Q9WTX7	Gene names	Fhl5, Act
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

PDZD7_HUMAN
NC score	0.383834 (rank : 53)	θ value	0.0113563 (rank : 69)
Query Neighborhood Hits	245	Target Neighborhood Hits	181	Shared Neighborhood Hits	108
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

FHL5_HUMAN
NC score	0.378042 (rank : 54)	θ value	0.125558 (rank : 124)
Query Neighborhood Hits	245	Target Neighborhood Hits	523	Shared Neighborhood Hits	117
SwissProt Accessions	Q5TD97, Q5TD98, Q8WW21, Q9NQU2	Gene names	FHL5, ACT
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

LMCD1_HUMAN
NC score	0.375200 (rank : 55)	θ value	0.47712 (rank : 164)
Query Neighborhood Hits	245	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZU5	Gene names	LMCD1
Domain Architecture
Description	LIM and cysteine-rich domains protein 1 (Dyxin).

CSRP2_MOUSE
NC score	0.369781 (rank : 56)	θ value	0.0736092 (rank : 104)
Query Neighborhood Hits	245	Target Neighborhood Hits	152	Shared Neighborhood Hits	109
SwissProt Accessions	P97314, Q9CZG5	Gene names	Csrp2, Dlp1
Domain Architecture
Description	Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (Double LIM protein 1) (DLP-1).

LMCD1_MOUSE
NC score	0.369387 (rank : 57)	θ value	0.0252991 (rank : 83)
Query Neighborhood Hits	245	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VEE1	Gene names	Lmcd1
Domain Architecture
Description	LIM and cysteine-rich domains protein 1.

CSRP1_MOUSE
NC score	0.367877 (rank : 58)	θ value	0.00298849 (rank : 50)
Query Neighborhood Hits	245	Target Neighborhood Hits	132	Shared Neighborhood Hits	107
SwissProt Accessions	P97315	Gene names	Csrp1, Crp1, Csrp
Domain Architecture
Description	Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP1) (CRP).

CSRP2_HUMAN
NC score	0.367371 (rank : 59)	θ value	0.0736092 (rank : 103)
Query Neighborhood Hits	245	Target Neighborhood Hits	150	Shared Neighborhood Hits	109
SwissProt Accessions	Q16527, Q93030	Gene names	CSRP2, LMO5, SMLIM
Domain Architecture
Description	Cysteine and glycine-rich protein 2 (Cysteine-rich protein 2) (CRP2) (Smooth muscle cell LIM protein) (SmLIM) (LIM-only protein 5).

CSRP1_HUMAN
NC score	0.365497 (rank : 60)	θ value	0.00390308 (rank : 53)
Query Neighborhood Hits	245	Target Neighborhood Hits	128	Shared Neighborhood Hits	105
SwissProt Accessions	P21291	Gene names	CSRP1, CSRP, CYRP
Domain Architecture
Description	Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP1) (CRP).

LIN7A_HUMAN
NC score	0.362253 (rank : 61)	θ value	0.0193708 (rank : 77)
Query Neighborhood Hits	245	Target Neighborhood Hits	193	Shared Neighborhood Hits	107
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
NC score	0.361827 (rank : 62)	θ value	0.0193708 (rank : 78)
Query Neighborhood Hits	245	Target Neighborhood Hits	193	Shared Neighborhood Hits	107
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

NHERF_HUMAN
NC score	0.357829 (rank : 63)	θ value	0.00102713 (rank : 44)
Query Neighborhood Hits	245	Target Neighborhood Hits	190	Shared Neighborhood Hits	106
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

CSRP3_MOUSE
NC score	0.356163 (rank : 64)	θ value	0.125558 (rank : 122)
Query Neighborhood Hits	245	Target Neighborhood Hits	146	Shared Neighborhood Hits	108
SwissProt Accessions	P50462	Gene names	Csrp3, Clp, Mlp
Domain Architecture
Description	Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein).

LIN7B_HUMAN
NC score	0.355016 (rank : 65)	θ value	0.0563607 (rank : 97)
Query Neighborhood Hits	245	Target Neighborhood Hits	200	Shared Neighborhood Hits	106
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

NHRF2_MOUSE
NC score	0.354325 (rank : 66)	θ value	0.000270298 (rank : 39)
Query Neighborhood Hits	245	Target Neighborhood Hits	194	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

CSRP3_HUMAN
NC score	0.353427 (rank : 67)	θ value	0.125558 (rank : 121)
Query Neighborhood Hits	245	Target Neighborhood Hits	150	Shared Neighborhood Hits	108
SwissProt Accessions	P50461, Q9P131	Gene names	CSRP3, CLP, MLP
Domain Architecture
Description	Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein).

NHERF_MOUSE
NC score	0.351706 (rank : 68)	θ value	0.00175202 (rank : 48)
Query Neighborhood Hits	245	Target Neighborhood Hits	195	Shared Neighborhood Hits	106
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
NC score	0.351639 (rank : 69)	θ value	0.000270298 (rank : 38)
Query Neighborhood Hits	245	Target Neighborhood Hits	197	Shared Neighborhood Hits	106
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

LIN7B_MOUSE
NC score	0.350570 (rank : 70)	θ value	0.0736092 (rank : 108)
Query Neighborhood Hits	245	Target Neighborhood Hits	200	Shared Neighborhood Hits	106
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7C_HUMAN
NC score	0.345745 (rank : 71)	θ value	0.125558 (rank : 132)
Query Neighborhood Hits	245	Target Neighborhood Hits	198	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.345745 (rank : 72)	θ value	0.125558 (rank : 133)
Query Neighborhood Hits	245	Target Neighborhood Hits	198	Shared Neighborhood Hits	106
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

FHL2_HUMAN
NC score	0.345165 (rank : 73)	θ value	0.21417 (rank : 146)
Query Neighborhood Hits	245	Target Neighborhood Hits	533	Shared Neighborhood Hits	116
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

PDZ11_HUMAN
NC score	0.344377 (rank : 74)	θ value	0.279714 (rank : 155)
Query Neighborhood Hits	245	Target Neighborhood Hits	160	Shared Neighborhood Hits	99
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
NC score	0.341263 (rank : 75)	θ value	0.47712 (rank : 165)
Query Neighborhood Hits	245	Target Neighborhood Hits	154	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

FHL2_MOUSE
NC score	0.339649 (rank : 76)	θ value	0.163984 (rank : 139)
Query Neighborhood Hits	245	Target Neighborhood Hits	539	Shared Neighborhood Hits	116
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

WHRN_MOUSE
NC score	0.339157 (rank : 77)	θ value	0.0193708 (rank : 82)
Query Neighborhood Hits	245	Target Neighborhood Hits	412	Shared Neighborhood Hits	119
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

LMO4_HUMAN
NC score	0.339056 (rank : 78)	θ value	0.0961366 (rank : 115)
Query Neighborhood Hits	245	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	P61968, O00158, O88894	Gene names	LMO4
Domain Architecture
Description	LIM domain transcription factor LMO4 (LIM domain only protein 4) (LMO- 4) (Breast tumor autoantigen).

LMO4_MOUSE
NC score	0.339056 (rank : 79)	θ value	0.0961366 (rank : 116)
Query Neighborhood Hits	245	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	P61969, O00158, O88894	Gene names	Lmo4
Domain Architecture
Description	LIM domain transcription factor LMO4 (LIM domain only protein 4) (LMO- 4) (Breast tumor autoantigen).

WHRN_HUMAN
NC score	0.338436 (rank : 80)	θ value	0.0193708 (rank : 81)
Query Neighborhood Hits	245	Target Neighborhood Hits	325	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

MAGI1_HUMAN
NC score	0.334537 (rank : 81)	θ value	3.19293e-05 (rank : 26)
Query Neighborhood Hits	245	Target Neighborhood Hits	388	Shared Neighborhood Hits	112
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

USH1C_HUMAN
NC score	0.331848 (rank : 82)	θ value	0.125558 (rank : 135)
Query Neighborhood Hits	245	Target Neighborhood Hits	327	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

CRIP1_HUMAN
NC score	0.328821 (rank : 83)	θ value	0.62314 (rank : 167)
Query Neighborhood Hits	245	Target Neighborhood Hits	113	Shared Neighborhood Hits	100
SwissProt Accessions	P50238, Q13628, Q96J34	Gene names	CRIP1, CRIP
Domain Architecture
Description	Cysteine-rich protein 1 (Cysteine-rich intestinal protein) (CRIP) (Cysteine-rich heart protein) (hCRHP).

LHX9_MOUSE
NC score	0.328401 (rank : 84)	θ value	0.000158464 (rank : 35)
Query Neighborhood Hits	245	Target Neighborhood Hits	445	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WUH2, Q9QYQ5, Q9QYQ6, Q9QZ00, Q9WU44	Gene names	Lhx9
Domain Architecture
Description	LIM/homeobox protein Lhx9.

LHX9_HUMAN
NC score	0.328369 (rank : 85)	θ value	0.000158464 (rank : 34)
Query Neighborhood Hits	245	Target Neighborhood Hits	444	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NQ69, Q5VUE3, Q9BYU6, Q9NQ70	Gene names	LHX9
Domain Architecture
Description	LIM/homeobox protein Lhx9.

RBTN2_MOUSE
NC score	0.327504 (rank : 86)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	245	Target Neighborhood Hits	114	Shared Neighborhood Hits	103
SwissProt Accessions	P25801	Gene names	Lmo2, Rbtn-2, Rbtn2, Rhom-2
Domain Architecture
Description	Rhombotin-2 (Cysteine-rich protein TTG-2) (T-cell translocation protein 2) (LIM-only protein 2).

RBTN2_HUMAN
NC score	0.327494 (rank : 87)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	245	Target Neighborhood Hits	114	Shared Neighborhood Hits	103
SwissProt Accessions	P25791, Q9HD58	Gene names	LMO2, RBTN2, RHOM2, TTG2
Domain Architecture
Description	Rhombotin-2 (Cysteine-rich protein TTG-2) (T-cell translocation protein 2) (LIM-only protein 2).

MAGI2_HUMAN
NC score	0.326481 (rank : 88)	θ value	0.00665767 (rank : 62)
Query Neighborhood Hits	245	Target Neighborhood Hits	373	Shared Neighborhood Hits	114
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

SNTG1_MOUSE
NC score	0.322564 (rank : 89)	θ value	0.0252991 (rank : 85)
Query Neighborhood Hits	245	Target Neighborhood Hits	179	Shared Neighborhood Hits	106
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SYJ2B_HUMAN
NC score	0.321192 (rank : 90)	θ value	0.0431538 (rank : 96)
Query Neighborhood Hits	245	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

RBTN1_MOUSE
NC score	0.321112 (rank : 91)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	245	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	Q924W9	Gene names	Lmo1, Rbtn1, Rhom1, Ttg1
Domain Architecture	No domain graphic available
Description	Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM-only protein 1).

RBTN1_HUMAN
NC score	0.320591 (rank : 92)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	245	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	P25800, Q4VBC5	Gene names	LMO1, RBTN1, RHOM1, TTG1
Domain Architecture
Description	Rhombotin-1 (Cysteine-rich protein TTG-1) (T-cell translocation protein 1) (LIM-only protein 1).

SNTG1_HUMAN
NC score	0.319839 (rank : 93)	θ value	0.0330416 (rank : 90)
Query Neighborhood Hits	245	Target Neighborhood Hits	181	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

PDZD3_HUMAN
NC score	0.319551 (rank : 94)	θ value	0.0563607 (rank : 99)
Query Neighborhood Hits	245	Target Neighborhood Hits	180	Shared Neighborhood Hits	104
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

CRIP1_MOUSE
NC score	0.319246 (rank : 95)	θ value	1.81305 (rank : 185)
Query Neighborhood Hits	245	Target Neighborhood Hits	118	Shared Neighborhood Hits	100
SwissProt Accessions	P63254, P04006, Q3THF0	Gene names	Crip1, Crip
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 1 (Cysteine-rich intestinal protein) (CRIP).

LHX2_HUMAN
NC score	0.318348 (rank : 96)	θ value	0.00134147 (rank : 46)
Query Neighborhood Hits	245	Target Neighborhood Hits	432	Shared Neighborhood Hits	104
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

LHX2_MOUSE
NC score	0.317842 (rank : 97)	θ value	0.00134147 (rank : 47)
Query Neighborhood Hits	245	Target Neighborhood Hits	431	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

MAGI2_MOUSE
NC score	0.317346 (rank : 98)	θ value	0.00665767 (rank : 63)
Query Neighborhood Hits	245	Target Neighborhood Hits	370	Shared Neighborhood Hits	113
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

LMO3_HUMAN
NC score	0.317250 (rank : 99)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	245	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	Q8TAP4, Q8N974, Q9UDD5	Gene names	LMO3, RBTN3, RHOM3
Domain Architecture
Description	LIM-only protein 3 (Neuronal-specific transcription factor DAT1) (Rhombotin-3).

LMO3_MOUSE
NC score	0.317250 (rank : 100)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	245	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BZL8	Gene names	Lmo3
Domain Architecture
Description	LIM-only protein 3 (Neuronal-specific transcription factor DAT1).

MAGI1_MOUSE
NC score	0.316513 (rank : 101)	θ value	0.00665767 (rank : 61)
Query Neighborhood Hits	245	Target Neighborhood Hits	403	Shared Neighborhood Hits	111
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

SNTA1_MOUSE
NC score	0.313264 (rank : 102)	θ value	0.0113563 (rank : 70)
Query Neighborhood Hits	245	Target Neighborhood Hits	170	Shared Neighborhood Hits	104
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

SNTA1_HUMAN
NC score	0.312867 (rank : 103)	θ value	0.0193708 (rank : 80)
Query Neighborhood Hits	245	Target Neighborhood Hits	186	Shared Neighborhood Hits	105
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

LHX4_MOUSE
NC score	0.312424 (rank : 104)	θ value	0.0113563 (rank : 67)
Query Neighborhood Hits	245	Target Neighborhood Hits	457	Shared Neighborhood Hits	106
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LHX4_HUMAN
NC score	0.312290 (rank : 105)	θ value	0.0113563 (rank : 66)
Query Neighborhood Hits	245	Target Neighborhood Hits	455	Shared Neighborhood Hits	106
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

USH1C_MOUSE
NC score	0.311078 (rank : 106)	θ value	0.125558 (rank : 136)
Query Neighborhood Hits	245	Target Neighborhood Hits	557	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

LHX3_MOUSE
NC score	0.309015 (rank : 107)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	245	Target Neighborhood Hits	451	Shared Neighborhood Hits	108
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

LHX3_HUMAN
NC score	0.307605 (rank : 108)	θ value	0.00298849 (rank : 51)
Query Neighborhood Hits	245	Target Neighborhood Hits	474	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UBR4, Q9NZB5, Q9P0I8, Q9P0I9	Gene names	LHX3
Domain Architecture
Description	LIM/homeobox protein Lhx3.

LIMD2_HUMAN
NC score	0.307456 (rank : 109)	θ value	0.21417 (rank : 148)
Query Neighborhood Hits	245	Target Neighborhood Hits	106	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BT23, Q96S91	Gene names	LIMD2
Domain Architecture	No domain graphic available
Description	LIM domain-containing protein 2.

SNTG2_HUMAN
NC score	0.305612 (rank : 110)	θ value	0.163984 (rank : 143)
Query Neighborhood Hits	245	Target Neighborhood Hits	191	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

LIMD2_MOUSE
NC score	0.304183 (rank : 111)	θ value	0.47712 (rank : 163)
Query Neighborhood Hits	245	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BGB5	Gene names	Limd2
Domain Architecture	No domain graphic available
Description	LIM domain-containing protein 2.

LASP1_MOUSE
NC score	0.301125 (rank : 112)	θ value	0.000121331 (rank : 31)
Query Neighborhood Hits	245	Target Neighborhood Hits	297	Shared Neighborhood Hits	101
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

SNTB2_HUMAN
NC score	0.298907 (rank : 113)	θ value	0.279714 (rank : 156)
Query Neighborhood Hits	245	Target Neighborhood Hits	180	Shared Neighborhood Hits	97
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

GOPC_MOUSE
NC score	0.298694 (rank : 114)	θ value	0.125558 (rank : 125)
Query Neighborhood Hits	245	Target Neighborhood Hits	323	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

ISL2_HUMAN
NC score	0.298059 (rank : 115)	θ value	0.0330416 (rank : 88)
Query Neighborhood Hits	245	Target Neighborhood Hits	435	Shared Neighborhood Hits	99
SwissProt Accessions	Q96A47	Gene names	ISL2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

SNTB2_MOUSE
NC score	0.297830 (rank : 116)	θ value	0.279714 (rank : 157)
Query Neighborhood Hits	245	Target Neighborhood Hits	181	Shared Neighborhood Hits	97
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

LHX61_MOUSE
NC score	0.296733 (rank : 117)	θ value	0.125558 (rank : 131)
Query Neighborhood Hits	245	Target Neighborhood Hits	396	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R1R0, Q9R1R1	Gene names	Lhx6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1.

LASP1_HUMAN
NC score	0.296294 (rank : 118)	θ value	9.29e-05 (rank : 29)
Query Neighborhood Hits	245	Target Neighborhood Hits	293	Shared Neighborhood Hits	99
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ISL2_MOUSE
NC score	0.295198 (rank : 119)	θ value	0.0431538 (rank : 93)
Query Neighborhood Hits	245	Target Neighborhood Hits	426	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CXV0	Gene names	Isl2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

GOPC_HUMAN
NC score	0.295024 (rank : 120)	θ value	0.0961366 (rank : 114)
Query Neighborhood Hits	245	Target Neighborhood Hits	377	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SNTG2_MOUSE
NC score	0.292479 (rank : 121)	θ value	0.0961366 (rank : 120)
Query Neighborhood Hits	245	Target Neighborhood Hits	176	Shared Neighborhood Hits	105
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PDZD1_HUMAN
NC score	0.290681 (rank : 122)	θ value	0.0330416 (rank : 89)
Query Neighborhood Hits	245	Target Neighborhood Hits	190	Shared Neighborhood Hits	103
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ISL1_HUMAN
NC score	0.290296 (rank : 123)	θ value	0.125558 (rank : 128)
Query Neighborhood Hits	245	Target Neighborhood Hits	421	Shared Neighborhood Hits	97
SwissProt Accessions	P61371, P20663, P47894	Gene names	ISL1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

ISL1_MOUSE
NC score	0.290296 (rank : 124)	θ value	0.125558 (rank : 129)
Query Neighborhood Hits	245	Target Neighborhood Hits	421	Shared Neighborhood Hits	97
SwissProt Accessions	P61372, P20663, P47894, Q812D8	Gene names	Isl1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

SNTB1_HUMAN
NC score	0.290068 (rank : 125)	θ value	0.21417 (rank : 149)
Query Neighborhood Hits	245	Target Neighborhood Hits	157	Shared Neighborhood Hits	98
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

PDZD1_MOUSE
NC score	0.288360 (rank : 126)	θ value	0.0113563 (rank : 68)
Query Neighborhood Hits	245	Target Neighborhood Hits	191	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SNTB1_MOUSE
NC score	0.288047 (rank : 127)	θ value	0.21417 (rank : 150)
Query Neighborhood Hits	245	Target Neighborhood Hits	160	Shared Neighborhood Hits	98
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

LHX61_HUMAN
NC score	0.286509 (rank : 128)	θ value	0.125558 (rank : 130)
Query Neighborhood Hits	245	Target Neighborhood Hits	412	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UPM6, Q5T7S8, Q9NTK3, Q9UPM5	Gene names	LHX6, LHX6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1 (Lhx6).

PDZD3_MOUSE
NC score	0.285175 (rank : 129)	θ value	2.36792 (rank : 193)
Query Neighborhood Hits	245	Target Neighborhood Hits	171	Shared Neighborhood Hits	103
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

TX1B3_MOUSE
NC score	0.284885 (rank : 130)	θ value	0.62314 (rank : 174)
Query Neighborhood Hits	245	Target Neighborhood Hits	158	Shared Neighborhood Hits	96
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

CRIP2_HUMAN
NC score	0.284877 (rank : 131)	θ value	0.62314 (rank : 168)
Query Neighborhood Hits	245	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P52943	Gene names	CRIP2, CRP2
Domain Architecture
Description	Cysteine-rich protein 2 (CRP2) (Protein ESP1).

TX1B3_HUMAN
NC score	0.284808 (rank : 132)	θ value	0.62314 (rank : 173)
Query Neighborhood Hits	245	Target Neighborhood Hits	161	Shared Neighborhood Hits	96
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

GRASP_HUMAN
NC score	0.283818 (rank : 133)	θ value	0.0193708 (rank : 75)
Query Neighborhood Hits	245	Target Neighborhood Hits	147	Shared Neighborhood Hits	98
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

LHX8_MOUSE
NC score	0.282650 (rank : 134)	θ value	0.0736092 (rank : 107)
Query Neighborhood Hits	245	Target Neighborhood Hits	406	Shared Neighborhood Hits	96
SwissProt Accessions	O35652, O70163, O88707	Gene names	Lhx8, Lhx7
Domain Architecture
Description	LIM/homeobox protein Lhx8 (LIM homeodomain Lhx7) (L3).

GRASP_MOUSE
NC score	0.281915 (rank : 135)	θ value	0.0193708 (rank : 76)
Query Neighborhood Hits	245	Target Neighborhood Hits	131	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

LIMA1_MOUSE
NC score	0.277443 (rank : 136)	θ value	0.0148317 (rank : 72)
Query Neighborhood Hits	245	Target Neighborhood Hits	298	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

LHX6_MOUSE
NC score	0.276838 (rank : 137)	θ value	0.279714 (rank : 154)
Query Neighborhood Hits	245	Target Neighborhood Hits	399	Shared Neighborhood Hits	98
SwissProt Accessions	O88706	Gene names	Lhx6
Domain Architecture
Description	LIM/homeobox protein Lhx6.

LMX1A_MOUSE
NC score	0.275803 (rank : 138)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	245	Target Neighborhood Hits	405	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JKU8	Gene names	Lmx1a
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

LHX5_MOUSE
NC score	0.275361 (rank : 139)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	245	Target Neighborhood Hits	456	Shared Neighborhood Hits	103
SwissProt Accessions	P61375, P50459	Gene names	Lhx5
Domain Architecture
Description	LIM/homeobox protein Lhx5.

LHX5_HUMAN
NC score	0.274157 (rank : 140)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	245	Target Neighborhood Hits	453	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H2C1	Gene names	LHX5
Domain Architecture
Description	LIM/homeobox protein Lhx5.

LMX1B_MOUSE
NC score	0.274107 (rank : 141)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	245	Target Neighborhood Hits	394	Shared Neighborhood Hits	96
SwissProt Accessions	O88609	Gene names	Lmx1b
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

LMX1B_HUMAN
NC score	0.273379 (rank : 142)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	245	Target Neighborhood Hits	404	Shared Neighborhood Hits	96
SwissProt Accessions	O60663, O75463	Gene names	LMX1B
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

LMX1A_HUMAN
NC score	0.272123 (rank : 143)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	245	Target Neighborhood Hits	406	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TE12, Q8TE11	Gene names	LMX1A
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

MPDZ_MOUSE
NC score	0.269305 (rank : 144)	θ value	0.00390308 (rank : 55)
Query Neighborhood Hits	245	Target Neighborhood Hits	298	Shared Neighborhood Hits	109
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

LHX1_HUMAN
NC score	0.268960 (rank : 145)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	245	Target Neighborhood Hits	453	Shared Neighborhood Hits	102
SwissProt Accessions	P48742, Q3MIW0	Gene names	LHX1, LIM1
Domain Architecture
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

LHX1_MOUSE
NC score	0.268859 (rank : 146)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	245	Target Neighborhood Hits	453	Shared Neighborhood Hits	102
SwissProt Accessions	P63006, P36199	Gene names	Lhx1, Lim-1, Lim1
Domain Architecture	No domain graphic available
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

LIMA1_HUMAN
NC score	0.267351 (rank : 147)	θ value	0.0431538 (rank : 94)
Query Neighborhood Hits	245	Target Neighborhood Hits	309	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

RHPN1_MOUSE
NC score	0.264371 (rank : 148)	θ value	0.0961366 (rank : 119)
Query Neighborhood Hits	245	Target Neighborhood Hits	154	Shared Neighborhood Hits	101
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

GRIP1_MOUSE
NC score	0.262859 (rank : 149)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	245	Target Neighborhood Hits	241	Shared Neighborhood Hits	111
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

INADL_MOUSE
NC score	0.262534 (rank : 150)	θ value	0.125558 (rank : 127)
Query Neighborhood Hits	245	Target Neighborhood Hits	290	Shared Neighborhood Hits	110
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

MPDZ_HUMAN
NC score	0.262267 (rank : 151)	θ value	0.00509761 (rank : 57)
Query Neighborhood Hits	245	Target Neighborhood Hits	261	Shared Neighborhood Hits	108
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

RHPN1_HUMAN
NC score	0.262107 (rank : 152)	θ value	0.0961366 (rank : 118)
Query Neighborhood Hits	245	Target Neighborhood Hits	158	Shared Neighborhood Hits	101
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

CRIP3_HUMAN
NC score	0.261288 (rank : 153)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	245	Target Neighborhood Hits	104	Shared Neighborhood Hits	91
SwissProt Accessions	Q6Q6R5, Q5T043, Q6Q6R4, Q6Q6R6, Q6Q6R7	Gene names	CRIP3
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Chromosome 6 LIM-only protein) (h6LIMo).

GRIP1_HUMAN
NC score	0.258777 (rank : 154)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	245	Target Neighborhood Hits	231	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP2_HUMAN
NC score	0.251203 (rank : 155)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	245	Target Neighborhood Hits	256	Shared Neighborhood Hits	112
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

INADL_HUMAN
NC score	0.250852 (rank : 156)	θ value	0.125558 (rank : 126)
Query Neighborhood Hits	245	Target Neighborhood Hits	260	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

CRIP2_MOUSE
NC score	0.250566 (rank : 157)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	245	Target Neighborhood Hits	98	Shared Neighborhood Hits	90
SwissProt Accessions	Q9DCT8	Gene names	Crip2, Crp2, Hlp
Domain Architecture
Description	Cysteine-rich protein 2 (CRP2) (Heart LIM protein).

LNX2_HUMAN
NC score	0.239834 (rank : 158)	θ value	0.0736092 (rank : 110)
Query Neighborhood Hits	245	Target Neighborhood Hits	389	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
NC score	0.236880 (rank : 159)	θ value	0.163984 (rank : 140)
Query Neighborhood Hits	245	Target Neighborhood Hits	407	Shared Neighborhood Hits	104
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RPGF6_HUMAN
NC score	0.230020 (rank : 160)	θ value	0.0148317 (rank : 73)
Query Neighborhood Hits	245	Target Neighborhood Hits	266	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

NRAP_HUMAN
NC score	0.228771 (rank : 161)	θ value	0.00869519 (rank : 65)
Query Neighborhood Hits	245	Target Neighborhood Hits	159	Shared Neighborhood Hits	98
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

NRAP_MOUSE
NC score	0.228060 (rank : 162)	θ value	0.0193708 (rank : 79)
Query Neighborhood Hits	245	Target Neighborhood Hits	167	Shared Neighborhood Hits	91
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

DLG4_MOUSE
NC score	0.221251 (rank : 163)	θ value	0.47712 (rank : 162)
Query Neighborhood Hits	245	Target Neighborhood Hits	282	Shared Neighborhood Hits	106
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.220963 (rank : 164)	θ value	0.47712 (rank : 161)
Query Neighborhood Hits	245	Target Neighborhood Hits	286	Shared Neighborhood Hits	106
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

ZO3_MOUSE
NC score	0.219201 (rank : 165)	θ value	0.279714 (rank : 158)
Query Neighborhood Hits	245	Target Neighborhood Hits	224	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

PSCBP_MOUSE
NC score	0.218432 (rank : 166)	θ value	2.36792 (rank : 194)
Query Neighborhood Hits	245	Target Neighborhood Hits	118	Shared Neighborhood Hits	97
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

DLG1_HUMAN
NC score	0.217944 (rank : 167)	θ value	0.125558 (rank : 123)
Query Neighborhood Hits	245	Target Neighborhood Hits	290	Shared Neighborhood Hits	98
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

PDZD2_HUMAN
NC score	0.217316 (rank : 168)	θ value	1.06291 (rank : 178)
Query Neighborhood Hits	245	Target Neighborhood Hits	772	Shared Neighborhood Hits	118
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

DLG3_MOUSE
NC score	0.213615 (rank : 169)	θ value	0.163984 (rank : 138)
Query Neighborhood Hits	245	Target Neighborhood Hits	274	Shared Neighborhood Hits	102
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.213398 (rank : 170)	θ value	0.163984 (rank : 137)
Query Neighborhood Hits	245	Target Neighborhood Hits	269	Shared Neighborhood Hits	101
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

IL16_HUMAN
NC score	0.209475 (rank : 171)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	245	Target Neighborhood Hits	207	Shared Neighborhood Hits	86
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

DLG1_MOUSE
NC score	0.206180 (rank : 172)	θ value	0.0961366 (rank : 112)
Query Neighborhood Hits	245	Target Neighborhood Hits	285	Shared Neighborhood Hits	97
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

LNX1_MOUSE
NC score	0.205800 (rank : 173)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	245	Target Neighborhood Hits	377	Shared Neighborhood Hits	100
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_HUMAN
NC score	0.203019 (rank : 174)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	245	Target Neighborhood Hits	379	Shared Neighborhood Hits	96
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

DLG2_HUMAN
NC score	0.196621 (rank : 175)	θ value	0.21417 (rank : 144)
Query Neighborhood Hits	245	Target Neighborhood Hits	279	Shared Neighborhood Hits	102
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

CRIP3_MOUSE
NC score	0.196548 (rank : 176)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	245	Target Neighborhood Hits	94	Shared Neighborhood Hits	80
SwissProt Accessions	Q6Q6R3, Q91V23, Q91V60	Gene names	Crip3, Tlp
Domain Architecture	No domain graphic available
Description	Cysteine-rich protein 3 (CRP3) (Thymus LIM protein) (m17TLP).

DLG2_MOUSE
NC score	0.196179 (rank : 177)	θ value	0.21417 (rank : 145)
Query Neighborhood Hits	245	Target Neighborhood Hits	271	Shared Neighborhood Hits	100
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PSCBP_HUMAN
NC score	0.194170 (rank : 178)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	245	Target Neighborhood Hits	123	Shared Neighborhood Hits	88
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

ZO3_HUMAN
NC score	0.194070 (rank : 179)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	245	Target Neighborhood Hits	219	Shared Neighborhood Hits	107
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

RPGF2_HUMAN
NC score	0.192041 (rank : 180)	θ value	0.0563607 (rank : 101)
Query Neighborhood Hits	245	Target Neighborhood Hits	242	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

IL16_MOUSE
NC score	0.191746 (rank : 181)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	245	Target Neighborhood Hits	189	Shared Neighborhood Hits	82
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LAP4_HUMAN
NC score	0.180788 (rank : 182)	θ value	0.21417 (rank : 147)
Query Neighborhood Hits	245	Target Neighborhood Hits	608	Shared Neighborhood Hits	118
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
NC score	0.169130 (rank : 183)	θ value	0.279714 (rank : 153)
Query Neighborhood Hits	245	Target Neighborhood Hits	590	Shared Neighborhood Hits	114
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PARD3_MOUSE
NC score	0.167586 (rank : 184)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	245	Target Neighborhood Hits	290	Shared Neighborhood Hits	87
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PARD3_HUMAN
NC score	0.166333 (rank : 185)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	245	Target Neighborhood Hits	312	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

RGS12_HUMAN
NC score	0.162661 (rank : 186)	θ value	0.163984 (rank : 142)
Query Neighborhood Hits	245	Target Neighborhood Hits	333	Shared Neighborhood Hits	104
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

ZO1_HUMAN
NC score	0.162482 (rank : 187)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	245	Target Neighborhood Hits	474	Shared Neighborhood Hits	107
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

PAR3L_HUMAN
NC score	0.162043 (rank : 188)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	245	Target Neighborhood Hits	297	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

ZO1_MOUSE
NC score	0.160367 (rank : 189)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	245	Target Neighborhood Hits	453	Shared Neighborhood Hits	106
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
NC score	0.158174 (rank : 190)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	245	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

LIMK1_HUMAN
NC score	0.150346 (rank : 191)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	245	Target Neighborhood Hits	1005	Shared Neighborhood Hits	160
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

ZO2_MOUSE
NC score	0.149364 (rank : 192)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	245	Target Neighborhood Hits	296	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

LIMK1_MOUSE
NC score	0.148739 (rank : 193)	θ value	0.00390308 (rank : 54)
Query Neighborhood Hits	245	Target Neighborhood Hits	1008	Shared Neighborhood Hits	157
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

PTN13_HUMAN
NC score	0.146280 (rank : 194)	θ value	0.0736092 (rank : 111)
Query Neighborhood Hits	245	Target Neighborhood Hits	471	Shared Neighborhood Hits	104
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

DLG5_HUMAN
NC score	0.144712 (rank : 195)	θ value	0.00665767 (rank : 58)
Query Neighborhood Hits	245	Target Neighborhood Hits	1088	Shared Neighborhood Hits	106
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PTN13_MOUSE
NC score	0.143936 (rank : 196)	θ value	0.125558 (rank : 134)
Query Neighborhood Hits	245	Target Neighborhood Hits	426	Shared Neighborhood Hits	106
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

ARHGB_HUMAN
NC score	0.141953 (rank : 197)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	245	Target Neighborhood Hits	375	Shared Neighborhood Hits	107
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PZRN4_HUMAN
NC score	0.137825 (rank : 198)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	245	Target Neighborhood Hits	438	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PZRN3_MOUSE
NC score	0.133534 (rank : 199)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	245	Target Neighborhood Hits	447	Shared Neighborhood Hits	87
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.131339 (rank : 200)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	245	Target Neighborhood Hits	461	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SHAN2_HUMAN
NC score	0.123716 (rank : 201)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	245	Target Neighborhood Hits	346	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

LIMK2_MOUSE
NC score	0.123496 (rank : 202)	θ value	1.06291 (rank : 177)
Query Neighborhood Hits	245	Target Neighborhood Hits	998	Shared Neighborhood Hits	145
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

PTN3_HUMAN
NC score	0.123432 (rank : 203)	θ value	0.0431538 (rank : 95)
Query Neighborhood Hits	245	Target Neighborhood Hits	258	Shared Neighborhood Hits	96
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

LIMK2_HUMAN
NC score	0.122284 (rank : 204)	θ value	0.813845 (rank : 176)
Query Neighborhood Hits	245	Target Neighborhood Hits	986	Shared Neighborhood Hits	146
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

K1849_HUMAN
NC score	0.121150 (rank : 205)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	245	Target Neighborhood Hits	220	Shared Neighborhood Hits	81
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
NC score	0.120215 (rank : 206)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	245	Target Neighborhood Hits	335	Shared Neighborhood Hits	85
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ARHGC_HUMAN
NC score	0.112039 (rank : 207)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	245	Target Neighborhood Hits	351	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.111147 (rank : 208)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	245	Target Neighborhood Hits	344	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SHAN2_MOUSE
NC score	0.109004 (rank : 209)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	245	Target Neighborhood Hits	446	Shared Neighborhood Hits	92
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

AFAD_HUMAN
NC score	0.108060 (rank : 210)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	245	Target Neighborhood Hits	689	Shared Neighborhood Hits	83
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

PTN4_HUMAN
NC score	0.107043 (rank : 211)	θ value	0.365318 (rank : 160)
Query Neighborhood Hits	245	Target Neighborhood Hits	303	Shared Neighborhood Hits	93
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

MICA2_MOUSE
NC score	0.105173 (rank : 212)	θ value	0.163984 (rank : 141)
Query Neighborhood Hits	245	Target Neighborhood Hits	144	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BML1, Q3UPU6	Gene names	Mical2
Domain Architecture
Description	Protein MICAL-2.

SDCB1_MOUSE
NC score	0.105008 (rank : 213)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	245	Target Neighborhood Hits	144	Shared Neighborhood Hits	83
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

MICA3_HUMAN
NC score	0.102816 (rank : 214)	θ value	1.81305 (rank : 187)
Query Neighborhood Hits	245	Target Neighborhood Hits	160	Shared Neighborhood Hits	87
SwissProt Accessions	Q7RTP6, Q6ICK4, Q9P2I3	Gene names	MICAL3, KIAA1364
Domain Architecture
Description	Protein MICAL-3.

MICA2_HUMAN
NC score	0.101187 (rank : 215)	θ value	0.62314 (rank : 169)
Query Neighborhood Hits	245	Target Neighborhood Hits	174	Shared Neighborhood Hits	80
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

SDCB1_HUMAN
NC score	0.100728 (rank : 216)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	245	Target Neighborhood Hits	150	Shared Neighborhood Hits	83
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

PICK1_HUMAN
NC score	0.099840 (rank : 217)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	245	Target Neighborhood Hits	132	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
NC score	0.099656 (rank : 218)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	245	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

MPP4_HUMAN
NC score	0.098629 (rank : 219)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	245	Target Neighborhood Hits	205	Shared Neighborhood Hits	74
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

SDCB2_HUMAN
NC score	0.095910 (rank : 220)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	245	Target Neighborhood Hits	121	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

APBA2_HUMAN
NC score	0.091877 (rank : 221)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	245	Target Neighborhood Hits	220	Shared Neighborhood Hits	80
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

DEMA_HUMAN
NC score	0.090912 (rank : 222)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	245	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q08495, Q13215, Q9BRE3	Gene names	EPB49, DMT
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

DEMA_MOUSE
NC score	0.090201 (rank : 223)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	245	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

PAR6G_HUMAN
NC score	0.089349 (rank : 224)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	245	Target Neighborhood Hits	159	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

APBA1_HUMAN
NC score	0.088471 (rank : 225)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	245	Target Neighborhood Hits	325	Shared Neighborhood Hits	78
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PAR6B_MOUSE
NC score	0.088167 (rank : 226)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	245	Target Neighborhood Hits	128	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_HUMAN
NC score	0.088057 (rank : 227)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	245	Target Neighborhood Hits	126	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

SDCB2_MOUSE
NC score	0.087605 (rank : 228)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	245	Target Neighborhood Hits	118	Shared Neighborhood Hits	67
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

APBA2_MOUSE
NC score	0.087263 (rank : 229)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	245	Target Neighborhood Hits	219	Shared Neighborhood Hits	79
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
NC score	0.086462 (rank : 230)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	245	Target Neighborhood Hits	201	Shared Neighborhood Hits	76
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6G_MOUSE
NC score	0.086285 (rank : 231)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	245	Target Neighborhood Hits	121	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

MPP3_MOUSE
NC score	0.085613 (rank : 232)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	245	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_MOUSE
NC score	0.085610 (rank : 233)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	245	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP3_HUMAN
NC score	0.085358 (rank : 234)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	245	Target Neighborhood Hits	171	Shared Neighborhood Hits	68
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP5_HUMAN
NC score	0.084807 (rank : 235)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	245	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.084510 (rank : 236)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	245	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

LMO7_HUMAN
NC score	0.084005 (rank : 237)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	245	Target Neighborhood Hits	507	Shared Neighborhood Hits	97
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

APBA3_MOUSE
NC score	0.081129 (rank : 238)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	245	Target Neighborhood Hits	174	Shared Neighborhood Hits	74
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

MILK2_HUMAN
NC score	0.079919 (rank : 239)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	245	Target Neighborhood Hits	457	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

NOS1_HUMAN
NC score	0.079866 (rank : 240)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	245	Target Neighborhood Hits	218	Shared Neighborhood Hits	82
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SYNPO_MOUSE
NC score	0.079807 (rank : 241)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	245	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

PDZK4_MOUSE
NC score	0.078735 (rank : 242)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	245	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_HUMAN
NC score	0.078412 (rank : 243)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	245	Target Neighborhood Hits	165	Shared Neighborhood Hits	67
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

STXB4_HUMAN
NC score	0.077802 (rank : 244)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	245	Target Neighborhood Hits	616	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYNPO_HUMAN
NC score	0.077463 (rank : 245)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	245	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SHAN1_HUMAN
NC score	0.077233 (rank : 246)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	245	Target Neighborhood Hits	1041	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PAR6A_MOUSE
NC score	0.076953 (rank : 247)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	245	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

MILK1_MOUSE
NC score	0.076913 (rank : 248)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	245	Target Neighborhood Hits	788	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NEB1_HUMAN
NC score	0.076682 (rank : 249)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	245	Target Neighborhood Hits	829	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PAR6A_HUMAN
NC score	0.076605 (rank : 250)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	245	Target Neighborhood Hits	119	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

DVL3_MOUSE
NC score	0.076245 (rank : 251)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	245	Target Neighborhood Hits	198	Shared Neighborhood Hits	63
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL2_HUMAN
NC score	0.075660 (rank : 252)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	245	Target Neighborhood Hits	223	Shared Neighborhood Hits	65
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL1_HUMAN
NC score	0.075569 (rank : 253)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	245	Target Neighborhood Hits	158	Shared Neighborhood Hits	65
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

EM55_HUMAN
NC score	0.075350 (rank : 254)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	245	Target Neighborhood Hits	228	Shared Neighborhood Hits	67
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

ZN185_HUMAN
NC score	0.075326 (rank : 255)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	245	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

STXB4_MOUSE
NC score	0.075205 (rank : 256)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	245	Target Neighborhood Hits	629	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DVL3_HUMAN
NC score	0.075050 (rank : 257)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	245	Target Neighborhood Hits	194	Shared Neighborhood Hits	60
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1_MOUSE
NC score	0.073638 (rank : 258)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	245	Target Neighborhood Hits	146	Shared Neighborhood Hits	63
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

EM55_MOUSE
NC score	0.072074 (rank : 259)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	245	Target Neighborhood Hits	221	Shared Neighborhood Hits	65
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

DVL2_MOUSE
NC score	0.071758 (rank : 260)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	245	Target Neighborhood Hits	233	Shared Neighborhood Hits	63
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

NEB2_HUMAN
NC score	0.071297 (rank : 261)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	245	Target Neighborhood Hits	883	Shared Neighborhood Hits	64
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

DVL1L_HUMAN
NC score	0.071062 (rank : 262)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	245	Target Neighborhood Hits	146	Shared Neighborhood Hits	63
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

NEB2_MOUSE
NC score	0.070976 (rank : 263)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	245	Target Neighborhood Hits	889	Shared Neighborhood Hits	66
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

RHPN2_MOUSE
NC score	0.068131 (rank : 264)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	245	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

NOS1_MOUSE
NC score	0.068045 (rank : 265)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	245	Target Neighborhood Hits	155	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

LRRC7_HUMAN
NC score	0.062650 (rank : 266)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	245	Target Neighborhood Hits	423	Shared Neighborhood Hits	79
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.062051 (rank : 267)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	245	Target Neighborhood Hits	416	Shared Neighborhood Hits	81
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MICA1_HUMAN
NC score	0.061374 (rank : 268)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	245	Target Neighborhood Hits	279	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

PCLO_MOUSE
NC score	0.061230 (rank : 269)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	245	Target Neighborhood Hits	2275	Shared Neighborhood Hits	112
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MPP6_MOUSE
NC score	0.061133 (rank : 270)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	245	Target Neighborhood Hits	187	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP2_MOUSE
NC score	0.060214 (rank : 271)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	245	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP2_HUMAN
NC score	0.059177 (rank : 272)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	245	Target Neighborhood Hits	173	Shared Neighborhood Hits	57
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP6_HUMAN
NC score	0.058689 (rank : 273)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	245	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MILK1_HUMAN
NC score	0.056398 (rank : 274)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	245	Target Neighborhood Hits	427	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

GIPC1_MOUSE
NC score	0.056370 (rank : 275)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	245	Target Neighborhood Hits	92	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

LAP2_HUMAN
NC score	0.056102 (rank : 276)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	245	Target Neighborhood Hits	499	Shared Neighborhood Hits	70
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

RIMS1_HUMAN
NC score	0.055616 (rank : 277)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	245	Target Neighborhood Hits	437	Shared Neighborhood Hits	77
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

LAP2_MOUSE
NC score	0.053849 (rank : 278)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	245	Target Neighborhood Hits	482	Shared Neighborhood Hits	73
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MICA3_MOUSE
NC score	0.052507 (rank : 279)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	245	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CJ19, Q80TE8, Q8BXB1	Gene names	Mical3, Kiaa1364
Domain Architecture
Description	Protein MICAL-3.

MICA1_MOUSE
NC score	0.050289 (rank : 280)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	245	Target Neighborhood Hits	400	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MAST1_MOUSE
NC score	0.048187 (rank : 281)	θ value	0.0252991 (rank : 84)
Query Neighborhood Hits	245	Target Neighborhood Hits	1123	Shared Neighborhood Hits	98
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_HUMAN
NC score	0.047903 (rank : 282)	θ value	0.0563607 (rank : 98)
Query Neighborhood Hits	245	Target Neighborhood Hits	1146	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MUC1_HUMAN
NC score	0.047282 (rank : 283)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	245	Target Neighborhood Hits	975	Shared Neighborhood Hits	47
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MAST4_HUMAN
NC score	0.044290 (rank : 284)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	245	Target Neighborhood Hits	1804	Shared Neighborhood Hits	114
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

RGS3_HUMAN
NC score	0.044195 (rank : 285)	θ value	0.47712 (rank : 166)
Query Neighborhood Hits	245	Target Neighborhood Hits	1375	Shared Neighborhood Hits	74
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PRB4S_HUMAN
NC score	0.043744 (rank : 286)	θ value	0.62314 (rank : 171)
Query Neighborhood Hits	245	Target Neighborhood Hits	330	Shared Neighborhood Hits	22
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

MDC1_MOUSE
NC score	0.042847 (rank : 287)	θ value	1.81305 (rank : 186)
Query Neighborhood Hits	245	Target Neighborhood Hits	998	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MAST2_MOUSE
NC score	0.041149 (rank : 288)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	245	Target Neighborhood Hits	1110	Shared Neighborhood Hits	102
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MLL3_MOUSE
NC score	0.041028 (rank : 289)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	245	Target Neighborhood Hits	1399	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MAST2_HUMAN
NC score	0.040876 (rank : 290)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	245	Target Neighborhood Hits	1189	Shared Neighborhood Hits	100
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST3_HUMAN
NC score	0.037536 (rank : 291)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	245	Target Neighborhood Hits	1128	Shared Neighborhood Hits	92
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

ARVC_HUMAN
NC score	0.036198 (rank : 292)	θ value	0.0193708 (rank : 74)
Query Neighborhood Hits	245	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
NC score	0.035464 (rank : 293)	θ value	0.0431538 (rank : 91)
Query Neighborhood Hits	245	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

MTSS1_MOUSE
NC score	0.031933 (rank : 294)	θ value	0.365318 (rank : 159)
Query Neighborhood Hits	245	Target Neighborhood Hits	592	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

BSN_MOUSE
NC score	0.031091 (rank : 295)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	245	Target Neighborhood Hits	2057	Shared Neighborhood Hits	59
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MTSS1_HUMAN
NC score	0.029627 (rank : 296)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	245	Target Neighborhood Hits	504	Shared Neighborhood Hits	19
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

IRS2_MOUSE
NC score	0.026445 (rank : 297)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	245	Target Neighborhood Hits	248	Shared Neighborhood Hits	21
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

DMRTA_MOUSE
NC score	0.024257 (rank : 298)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	245	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFG4	Gene names	Dmrta1, Dmrt4
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1 (Doublesex- and mab-3-related transcription factor 4).

MY18A_MOUSE
NC score	0.022112 (rank : 299)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	245	Target Neighborhood Hits	1989	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ENAH_MOUSE
NC score	0.021705 (rank : 300)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	245	Target Neighborhood Hits	919	Shared Neighborhood Hits	36
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

TARA_MOUSE
NC score	0.019669 (rank : 301)	θ value	0.62314 (rank : 172)
Query Neighborhood Hits	245	Target Neighborhood Hits	1133	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CCDC3_MOUSE
NC score	0.016669 (rank : 302)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	245	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

PWWP2_HUMAN
NC score	0.015143 (rank : 303)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	245	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

MAML1_MOUSE
NC score	0.014850 (rank : 304)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	245	Target Neighborhood Hits	279	Shared Neighborhood Hits	9
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

LR37A_HUMAN
NC score	0.014819 (rank : 305)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	245	Target Neighborhood Hits	720	Shared Neighborhood Hits	26
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

CRTC1_HUMAN
NC score	0.014093 (rank : 306)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	245	Target Neighborhood Hits	319	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

F125B_HUMAN
NC score	0.013578 (rank : 307)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	245	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7P6, Q8N6S7	Gene names	FAM125B, C9orf28
Domain Architecture	No domain graphic available
Description	Protein FAM125B.

JADE2_MOUSE
NC score	0.013542 (rank : 308)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	245	Target Neighborhood Hits	560	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

F125B_MOUSE
NC score	0.012624 (rank : 309)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	245	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q6KAU4, Q6PB42	Gene names	Fam125b
Domain Architecture	No domain graphic available
Description	Protein FAM125B.

GP112_HUMAN
NC score	0.010768 (rank : 310)	θ value	0.813845 (rank : 175)
Query Neighborhood Hits	245	Target Neighborhood Hits	441	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

ZNF96_HUMAN
NC score	0.010126 (rank : 311)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	245	Target Neighborhood Hits	869	Shared Neighborhood Hits	53
SwissProt Accessions	O43309, O43724	Gene names	ZNF96, KIAA0426, ZNF305, ZSCAN12
Domain Architecture
Description	Zinc finger protein 96 (Zinc finger protein 305) (Zinc finger and SCAN domain-containing protein 12).

ZN337_HUMAN
NC score	0.009975 (rank : 312)	θ value	0.21417 (rank : 152)
Query Neighborhood Hits	245	Target Neighborhood Hits	781	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y3M9, Q9Y3Y5	Gene names	ZNF337
Domain Architecture
Description	Zinc finger protein 337.

ENAH_HUMAN
NC score	0.007829 (rank : 313)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	245	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PAK4_MOUSE
NC score	0.005755 (rank : 314)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	245	Target Neighborhood Hits	1098	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

ETV5_MOUSE
NC score	0.004999 (rank : 315)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	245	Target Neighborhood Hits	328	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

ULK1_HUMAN
NC score	0.004666 (rank : 316)	θ value	1.81305 (rank : 188)
Query Neighborhood Hits	245	Target Neighborhood Hits	1121	Shared Neighborhood Hits	23
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZNF25_HUMAN
NC score	0.004549 (rank : 317)	θ value	2.36792 (rank : 196)
Query Neighborhood Hits	245	Target Neighborhood Hits	763	Shared Neighborhood Hits	29
SwissProt Accessions	P17030, Q8IYE3, Q8NDD6, Q96MU2	Gene names	ZNF25, KOX19
Domain Architecture
Description	Zinc finger protein 25 (Zinc finger protein KOX19).

TMPSD_MOUSE
NC score	0.004530 (rank : 318)	θ value	0.21417 (rank : 151)
Query Neighborhood Hits	245	Target Neighborhood Hits	334	Shared Neighborhood Hits	11
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ZN584_HUMAN
NC score	0.004068 (rank : 319)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	245	Target Neighborhood Hits	741	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IVC4	Gene names	ZNF584
Domain Architecture	No domain graphic available
Description	Zinc finger protein 584.

COIA1_MOUSE
NC score	0.003949 (rank : 320)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	245	Target Neighborhood Hits	481	Shared Neighborhood Hits	16
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

OBSCN_HUMAN
NC score	0.003719 (rank : 321)	θ value	0.62314 (rank : 170)
Query Neighborhood Hits	245	Target Neighborhood Hits	1931	Shared Neighborhood Hits	34
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ZN260_MOUSE
NC score	0.003708 (rank : 322)	θ value	2.36792 (rank : 195)
Query Neighborhood Hits	245	Target Neighborhood Hits	765	Shared Neighborhood Hits	31
SwissProt Accessions	Q62513, Q3U170, Q8C2Q6, Q9R2B4	Gene names	Znf260, Zfp260
Domain Architecture	No domain graphic available
Description	Zinc finger protein 260 (Zfp-260).

ZNF32_MOUSE
NC score	0.003700 (rank : 323)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	245	Target Neighborhood Hits	737	Shared Neighborhood Hits	29
SwissProt Accessions	Q80V23, Q3UIS3	Gene names	Znf32, Zfp637
Domain Architecture	No domain graphic available
Description	Zinc finger protein 32 (Zinc finger protein 637).

GLI4_HUMAN
NC score	0.003262 (rank : 324)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	245	Target Neighborhood Hits	735	Shared Neighborhood Hits	29
SwissProt Accessions	P10075, Q96CK9	Gene names	GLI4, HKR4
Domain Architecture
Description	Zinc finger protein GLI4 (Krueppel-related zinc finger protein 4) (Protein HKR4).

ZN230_HUMAN
NC score	0.003207 (rank : 325)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	245	Target Neighborhood Hits	750	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UIE0, O15322, Q9P1U6	Gene names	ZNF230, FDZF2
Domain Architecture
Description	Zinc finger protein 230 (Zinc finger protein FDZF2).

ADA12_MOUSE
NC score	0.003143 (rank : 326)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	245	Target Neighborhood Hits	474	Shared Neighborhood Hits	14
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

AZI1_HUMAN
NC score	0.002835 (rank : 327)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	245	Target Neighborhood Hits	1000	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

ZNF32_HUMAN
NC score	0.002031 (rank : 328)	θ value	3.0926 (rank : 205)
Query Neighborhood Hits	245	Target Neighborhood Hits	735	Shared Neighborhood Hits	24
SwissProt Accessions	P17041, Q92951	Gene names	ZNF32, KOX30
Domain Architecture	No domain graphic available
Description	Zinc finger protein 32 (Zinc finger protein KOX30) (C2H2-546).

TMPSD_HUMAN
NC score	0.001760 (rank : 329)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	245	Target Neighborhood Hits	333	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ZN545_HUMAN
NC score	0.001433 (rank : 330)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	245	Target Neighborhood Hits	744	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N141, Q8NC63, Q8TF53	Gene names	ZNF545, KIAA1948
Domain Architecture	No domain graphic available
Description	Zinc finger protein 545.

ADA15_MOUSE
NC score	0.001241 (rank : 331)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	245	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ZN545_MOUSE
NC score	0.001128 (rank : 332)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	245	Target Neighborhood Hits	739	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P9Y7, Q6ZPG0	Gene names	Znf545, Kiaa1948, Zfp82
Domain Architecture	No domain graphic available
Description	Zinc finger protein 545 (Zinc finger protein 82).