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Network neighborhood for query Sequence : ARVC_HUMAN

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ARVC_HUMAN
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARVC_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
θ value	0 (rank : 2)	NC score	0.995612 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

CTND1_HUMAN
θ value	0 (rank : 3)	NC score	0.974949 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_MOUSE
θ value	0 (rank : 4)	NC score	0.975107 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND2_HUMAN
θ value	5.41814e-138 (rank : 5)	NC score	0.925315 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	333	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CTND2_MOUSE
θ value	2.78268e-134 (rank : 6)	NC score	0.936130 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

PKP4_MOUSE
θ value	1.80368e-133 (rank : 7)	NC score	0.947803 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	129	Shared Neighborhood Hits	40
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP4_HUMAN
θ value	2.97994e-128 (rank : 8)	NC score	0.945767 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	107	Shared Neighborhood Hits	36
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP2_HUMAN
θ value	3.96481e-64 (rank : 9)	NC score	0.917456 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PKP3_HUMAN
θ value	5.17823e-64 (rank : 10)	NC score	0.910024 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
θ value	8.83269e-64 (rank : 11)	NC score	0.909052 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PKP1_HUMAN
θ value	1.41016e-61 (rank : 12)	NC score	0.904457 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP1_MOUSE
θ value	1.84173e-61 (rank : 13)	NC score	0.905882 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

CTNB1_HUMAN
θ value	3.41135e-07 (rank : 14)	NC score	0.323565 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	3.41135e-07 (rank : 15)	NC score	0.323637 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

ARMC4_HUMAN
θ value	5.81887e-07 (rank : 16)	NC score	0.405117 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

PLAK_MOUSE
θ value	1.09739e-05 (rank : 17)	NC score	0.289751 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

APC_HUMAN
θ value	0.000121331 (rank : 18)	NC score	0.231515 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	603	Shared Neighborhood Hits	36
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	0.000121331 (rank : 19)	NC score	0.237598 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	441	Shared Neighborhood Hits	32
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

PLAK_HUMAN
θ value	0.00390308 (rank : 20)	NC score	0.251343 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PDLI4_HUMAN
θ value	0.0193708 (rank : 21)	NC score	0.036198 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

CLIC6_HUMAN
θ value	0.0330416 (rank : 22)	NC score	0.021922 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	289	Shared Neighborhood Hits	7
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

IMA4_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.116203 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.116274 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

EDA_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.034255 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

SREC2_MOUSE
θ value	0.125558 (rank : 26)	NC score	0.009402 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	605	Shared Neighborhood Hits	10
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ASPP1_MOUSE
θ value	0.163984 (rank : 27)	NC score	0.018368 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	1244	Shared Neighborhood Hits	13
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

IMA7_HUMAN
θ value	0.163984 (rank : 28)	NC score	0.130150 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

ARMC6_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.085220 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

IMA5_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.130195 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

SSBP4_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.025425 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	753	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ARMC6_HUMAN
θ value	0.365318 (rank : 32)	NC score	0.084574 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NXE6, O94999, Q9BTH5	Gene names	ARMC6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

ARMX3_MOUSE
θ value	0.365318 (rank : 33)	NC score	0.072186 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BHS6, Q91VP8, Q9DC32	Gene names	Armcx3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3.

IMA1_MOUSE
θ value	0.365318 (rank : 34)	NC score	0.099217 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

NANO1_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.034915 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WY41	Gene names	NANOS1, NOS1
Domain Architecture
Description	Nanos homolog 1 (NOS-1) (EC_Rep1a).

XPC_MOUSE
θ value	0.365318 (rank : 36)	NC score	0.027458 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

ARMX3_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.071548 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UH62, Q53HC6, Q7LCF5, Q9NPE4	Gene names	ARMCX3, ALEX3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3 (Protein ALEX3) (ARM protein lost in epithelial cancers on chromosome X 3).

CASC3_MOUSE
θ value	0.47712 (rank : 38)	NC score	0.037476 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	333	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

IMA1_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.099336 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

RTDR1_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.082229 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

IMA7_MOUSE
θ value	0.813845 (rank : 41)	NC score	0.131616 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

KLF13_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.000445 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	757	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

CLAP2_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.020678 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	O75122, Q7L8F6, Q8N6R6, Q9BQT3, Q9BQT4, Q9H7A3, Q9NSZ2	Gene names	CLASP2, KIAA0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

HEAT3_MOUSE
θ value	1.06291 (rank : 44)	NC score	0.074819 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BQM4, Q8C731	Gene names	Heatr3
Domain Architecture
Description	HEAT repeat-containing protein 3.

K1849_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.012791 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

OGFR_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.016184 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	1582	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

EDA_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.026461 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

FOXC1_MOUSE
θ value	1.38821 (rank : 48)	NC score	0.006248 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

NACAM_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.029540 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	1866	Shared Neighborhood Hits	27
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ANK2_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.007008 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	1615	Shared Neighborhood Hits	21
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ARMX1_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.049126 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX83	Gene names	Armcx1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1.

UN45A_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.019157 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	129	Shared Neighborhood Hits	13
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

ADA2A_HUMAN
θ value	3.0926 (rank : 53)	NC score	-0.001106 (rank : 96)
Query Neighborhood Hits	95	Target Neighborhood Hits	911	Shared Neighborhood Hits	4
SwissProt Accessions	P08913, Q2XN99, Q86TH8, Q9BZK1	Gene names	ADRA2A, ADRA2R, ADRAR
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR) (Alpha-2 adrenergic receptor subtype C10).

HASP_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.014848 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

HRBL_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.009597 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	269	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

IMA2_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.119180 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

SHC1_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.006869 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

TCF20_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.017375 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	396	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ARMX1_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.056515 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P291, Q53HK2, Q9H2Q0	Gene names	ARMCX1, ALEX1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1 (Protein ALEX1) (ARM protein lost in epithelial cancers on chromosome X 1).

HEAT3_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.051002 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4Q2, Q8N525, Q8WV56, Q96CC9, Q9NWN7	Gene names	HEATR3
Domain Architecture
Description	HEAT repeat-containing protein 3.

IMA2_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.118380 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

MYST4_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.007458 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	416	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

ZN335_HUMAN
θ value	4.03905 (rank : 63)	NC score	-0.001391 (rank : 97)
Query Neighborhood Hits	95	Target Neighborhood Hits	973	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

AKAP4_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.009730 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

ANR47_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.004579 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	350	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ARMX2_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.046488 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ARMX2_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.041406 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	349	Shared Neighborhood Hits	19
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ASPP1_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.010523 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	956	Shared Neighborhood Hits	9
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ELF1_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.009906 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	139	Shared Neighborhood Hits	5
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

FOG1_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.001174 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	1237	Shared Neighborhood Hits	19
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

NR4A3_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.001970 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NRX1A_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.003808 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

AKAP5_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.013556 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

ARRD1_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.007649 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

CADH4_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.001067 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	P55283, Q2M208, Q5VZ44, Q9BZ05	Gene names	CDH4
Domain Architecture
Description	Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD).

CLAP2_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.016102 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

COX10_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.009780 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

GCH1_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.011595 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

HMMR_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.007915 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	1178	Shared Neighborhood Hits	9
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

IMA3_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.105554 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.105872 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	56	Shared Neighborhood Hits	31
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

KIF4A_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.000768 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	1033	Shared Neighborhood Hits	7
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MAPK5_HUMAN
θ value	6.88961 (rank : 83)	NC score	-0.002652 (rank : 99)
Query Neighborhood Hits	95	Target Neighborhood Hits	795	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IW41, O60491, Q86X46, Q9BVX9, Q9UG86	Gene names	MAPKAPK5, PRAK
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated protein kinase).

NCOA6_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.016075 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	1202	Shared Neighborhood Hits	21
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TCF20_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.013109 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	323	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CADH4_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.000849 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	P39038	Gene names	Cdh4
Domain Architecture
Description	Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD).

CCDC9_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.007979 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CS007_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.005976 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	401	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

IF38_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.009132 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

LYPD4_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.012758 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVP6	Gene names	Lypd4
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 4 precursor.

NANO1_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.018894 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WY3, Q3UTS9, Q8BIJ9	Gene names	Nanos1, Nos
Domain Architecture
Description	Nanos homolog 1.

NSD1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.004945 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TRI56_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.003205 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	339	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

ZBED4_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.013447 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O75132, Q9UGG8	Gene names	ZBED4, KIAA0637
Domain Architecture
Description	Zinc finger BED domain-containing protein 4.

ZNF12_HUMAN
θ value	8.99809 (rank : 95)	NC score	-0.002578 (rank : 98)
Query Neighborhood Hits	95	Target Neighborhood Hits	779	Shared Neighborhood Hits	6
SwissProt Accessions	P17014, Q9ULZ6	Gene names	ZNF12, GIOT3, KOX3, ZNF325
Domain Architecture	No domain graphic available
Description	Zinc finger protein 12 (Zinc finger protein KOX3) (Zinc finger protein 325) (Gonadotropin-inducible transcription repressor 3) (GIOT-3).

ARMC7_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.058872 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H6L4	Gene names	ARMC7
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 7.

ARMC7_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.060259 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UJZ3, Q8R599	Gene names	Armc7
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 7.

GDS1_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.148364 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

SPAG6_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.052603 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

Hits sorted by NC score

ARVC_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
NC score	0.995612 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

CTND1_MOUSE
NC score	0.975107 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
NC score	0.974949 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

PKP4_MOUSE
NC score	0.947803 (rank : 5)	θ value	1.80368e-133 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	129	Shared Neighborhood Hits	40
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP4_HUMAN
NC score	0.945767 (rank : 6)	θ value	2.97994e-128 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	107	Shared Neighborhood Hits	36
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

CTND2_MOUSE
NC score	0.936130 (rank : 7)	θ value	2.78268e-134 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.925315 (rank : 8)	θ value	5.41814e-138 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	333	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PKP2_HUMAN
NC score	0.917456 (rank : 9)	θ value	3.96481e-64 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PKP3_HUMAN
NC score	0.910024 (rank : 10)	θ value	5.17823e-64 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
NC score	0.909052 (rank : 11)	θ value	8.83269e-64 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PKP1_MOUSE
NC score	0.905882 (rank : 12)	θ value	1.84173e-61 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP1_HUMAN
NC score	0.904457 (rank : 13)	θ value	1.41016e-61 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

ARMC4_HUMAN
NC score	0.405117 (rank : 14)	θ value	5.81887e-07 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_MOUSE
NC score	0.323637 (rank : 15)	θ value	3.41135e-07 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.323565 (rank : 16)	θ value	3.41135e-07 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.289751 (rank : 17)	θ value	1.09739e-05 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
NC score	0.251343 (rank : 18)	θ value	0.00390308 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

APC_MOUSE
NC score	0.237598 (rank : 19)	θ value	0.000121331 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	441	Shared Neighborhood Hits	32
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.231515 (rank : 20)	θ value	0.000121331 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	603	Shared Neighborhood Hits	36
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

GDS1_HUMAN
NC score	0.148364 (rank : 21)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	95	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

IMA7_MOUSE
NC score	0.131616 (rank : 22)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA5_HUMAN
NC score	0.130195 (rank : 23)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_HUMAN
NC score	0.130150 (rank : 24)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA2_HUMAN
NC score	0.119180 (rank : 25)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
NC score	0.118380 (rank : 26)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA4_MOUSE
NC score	0.116274 (rank : 27)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA4_HUMAN
NC score	0.116203 (rank : 28)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA3_MOUSE
NC score	0.105872 (rank : 29)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	56	Shared Neighborhood Hits	31
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
NC score	0.105554 (rank : 30)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA1_HUMAN
NC score	0.099336 (rank : 31)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
NC score	0.099217 (rank : 32)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

ARMC6_MOUSE
NC score	0.085220 (rank : 33)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

ARMC6_HUMAN
NC score	0.084574 (rank : 34)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NXE6, O94999, Q9BTH5	Gene names	ARMC6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

RTDR1_HUMAN
NC score	0.082229 (rank : 35)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

HEAT3_MOUSE
NC score	0.074819 (rank : 36)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BQM4, Q8C731	Gene names	Heatr3
Domain Architecture
Description	HEAT repeat-containing protein 3.

ARMX3_MOUSE
NC score	0.072186 (rank : 37)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BHS6, Q91VP8, Q9DC32	Gene names	Armcx3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3.

ARMX3_HUMAN
NC score	0.071548 (rank : 38)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UH62, Q53HC6, Q7LCF5, Q9NPE4	Gene names	ARMCX3, ALEX3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3 (Protein ALEX3) (ARM protein lost in epithelial cancers on chromosome X 3).

ARMC7_MOUSE
NC score	0.060259 (rank : 39)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	95	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UJZ3, Q8R599	Gene names	Armc7
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 7.

ARMC7_HUMAN
NC score	0.058872 (rank : 40)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	95	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H6L4	Gene names	ARMC7
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 7.

ARMX1_HUMAN
NC score	0.056515 (rank : 41)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P291, Q53HK2, Q9H2Q0	Gene names	ARMCX1, ALEX1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1 (Protein ALEX1) (ARM protein lost in epithelial cancers on chromosome X 1).

SPAG6_HUMAN
NC score	0.052603 (rank : 42)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	95	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

HEAT3_HUMAN
NC score	0.051002 (rank : 43)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4Q2, Q8N525, Q8WV56, Q96CC9, Q9NWN7	Gene names	HEATR3
Domain Architecture
Description	HEAT repeat-containing protein 3.

ARMX1_MOUSE
NC score	0.049126 (rank : 44)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX83	Gene names	Armcx1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1.

ARMX2_HUMAN
NC score	0.046488 (rank : 45)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	134	Shared Neighborhood Hits	19
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ARMX2_MOUSE
NC score	0.041406 (rank : 46)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	349	Shared Neighborhood Hits	19
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

CASC3_MOUSE
NC score	0.037476 (rank : 47)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	333	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

PDLI4_HUMAN
NC score	0.036198 (rank : 48)	θ value	0.0193708 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

NANO1_HUMAN
NC score	0.034915 (rank : 49)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WY41	Gene names	NANOS1, NOS1
Domain Architecture
Description	Nanos homolog 1 (NOS-1) (EC_Rep1a).

EDA_MOUSE
NC score	0.034255 (rank : 50)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

NACAM_MOUSE
NC score	0.029540 (rank : 51)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	1866	Shared Neighborhood Hits	27
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

XPC_MOUSE
NC score	0.027458 (rank : 52)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

EDA_HUMAN
NC score	0.026461 (rank : 53)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

SSBP4_HUMAN
NC score	0.025425 (rank : 54)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	753	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CLIC6_HUMAN
NC score	0.021922 (rank : 55)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	289	Shared Neighborhood Hits	7
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CLAP2_HUMAN
NC score	0.020678 (rank : 56)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	O75122, Q7L8F6, Q8N6R6, Q9BQT3, Q9BQT4, Q9H7A3, Q9NSZ2	Gene names	CLASP2, KIAA0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

UN45A_MOUSE
NC score	0.019157 (rank : 57)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	129	Shared Neighborhood Hits	13
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

NANO1_MOUSE
NC score	0.018894 (rank : 58)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WY3, Q3UTS9, Q8BIJ9	Gene names	Nanos1, Nos
Domain Architecture
Description	Nanos homolog 1.

ASPP1_MOUSE
NC score	0.018368 (rank : 59)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	1244	Shared Neighborhood Hits	13
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TCF20_MOUSE
NC score	0.017375 (rank : 60)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	396	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

OGFR_HUMAN
NC score	0.016184 (rank : 61)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	1582	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CLAP2_MOUSE
NC score	0.016102 (rank : 62)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

NCOA6_HUMAN
NC score	0.016075 (rank : 63)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	1202	Shared Neighborhood Hits	21
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

HASP_MOUSE
NC score	0.014848 (rank : 64)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

AKAP5_HUMAN
NC score	0.013556 (rank : 65)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

ZBED4_HUMAN
NC score	0.013447 (rank : 66)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O75132, Q9UGG8	Gene names	ZBED4, KIAA0637
Domain Architecture
Description	Zinc finger BED domain-containing protein 4.

TCF20_HUMAN
NC score	0.013109 (rank : 67)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	323	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

K1849_HUMAN
NC score	0.012791 (rank : 68)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LYPD4_MOUSE
NC score	0.012758 (rank : 69)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVP6	Gene names	Lypd4
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 4 precursor.

GCH1_HUMAN
NC score	0.011595 (rank : 70)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

ASPP1_HUMAN
NC score	0.010523 (rank : 71)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	956	Shared Neighborhood Hits	9
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ELF1_MOUSE
NC score	0.009906 (rank : 72)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	139	Shared Neighborhood Hits	5
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

COX10_MOUSE
NC score	0.009780 (rank : 73)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

AKAP4_HUMAN
NC score	0.009730 (rank : 74)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

HRBL_MOUSE
NC score	0.009597 (rank : 75)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	269	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

SREC2_MOUSE
NC score	0.009402 (rank : 76)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	605	Shared Neighborhood Hits	10
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

IF38_HUMAN
NC score	0.009132 (rank : 77)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

CCDC9_MOUSE
NC score	0.007979 (rank : 78)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

HMMR_MOUSE
NC score	0.007915 (rank : 79)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	1178	Shared Neighborhood Hits	9
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

ARRD1_HUMAN
NC score	0.007649 (rank : 80)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5I2	Gene names	ARRDC1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

MYST4_MOUSE
NC score	0.007458 (rank : 81)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	416	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

ANK2_HUMAN
NC score	0.007008 (rank : 82)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	1615	Shared Neighborhood Hits	21
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SHC1_MOUSE
NC score	0.006869 (rank : 83)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

FOXC1_MOUSE
NC score	0.006248 (rank : 84)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

CS007_HUMAN
NC score	0.005976 (rank : 85)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	401	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

NSD1_MOUSE
NC score	0.004945 (rank : 86)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

ANR47_MOUSE
NC score	0.004579 (rank : 87)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	350	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NRX1A_HUMAN
NC score	0.003808 (rank : 88)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

TRI56_HUMAN
NC score	0.003205 (rank : 89)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	339	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

NR4A3_MOUSE
NC score	0.001970 (rank : 90)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

FOG1_MOUSE
NC score	0.001174 (rank : 91)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	1237	Shared Neighborhood Hits	19
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CADH4_HUMAN
NC score	0.001067 (rank : 92)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	P55283, Q2M208, Q5VZ44, Q9BZ05	Gene names	CDH4
Domain Architecture
Description	Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD).

CADH4_MOUSE
NC score	0.000849 (rank : 93)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	P39038	Gene names	Cdh4
Domain Architecture
Description	Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD).

KIF4A_MOUSE
NC score	0.000768 (rank : 94)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	1033	Shared Neighborhood Hits	7
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KLF13_MOUSE
NC score	0.000445 (rank : 95)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	757	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

ADA2A_HUMAN
NC score	-0.001106 (rank : 96)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	911	Shared Neighborhood Hits	4
SwissProt Accessions	P08913, Q2XN99, Q86TH8, Q9BZK1	Gene names	ADRA2A, ADRA2R, ADRAR
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR) (Alpha-2 adrenergic receptor subtype C10).

ZN335_HUMAN
NC score	-0.001391 (rank : 97)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	973	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ZNF12_HUMAN
NC score	-0.002578 (rank : 98)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	779	Shared Neighborhood Hits	6
SwissProt Accessions	P17014, Q9ULZ6	Gene names	ZNF12, GIOT3, KOX3, ZNF325
Domain Architecture	No domain graphic available
Description	Zinc finger protein 12 (Zinc finger protein KOX3) (Zinc finger protein 325) (Gonadotropin-inducible transcription repressor 3) (GIOT-3).

MAPK5_HUMAN
NC score	-0.002652 (rank : 99)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	795	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IW41, O60491, Q86X46, Q9BVX9, Q9UG86	Gene names	MAPKAPK5, PRAK
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 5 (EC 2.7.11.1) (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated protein kinase).