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Network neighborhood for query Sequence : ANR47_MOUSE

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ANR47_MOUSE
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ANR47_HUMAN
θ value	0 (rank : 1)	NC score	0.974803 (rank : 2)
Query Neighborhood Hits	350	Target Neighborhood Hits	369	Shared Neighborhood Hits	277
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR47_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	350	Target Neighborhood Hits	350	Shared Neighborhood Hits	350
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR25_MOUSE
θ value	5.86991e-92 (rank : 3)	NC score	0.927085 (rank : 4)
Query Neighborhood Hits	350	Target Neighborhood Hits	398	Shared Neighborhood Hits	246
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR15_HUMAN
θ value	5.33382e-77 (rank : 4)	NC score	0.924891 (rank : 5)
Query Neighborhood Hits	350	Target Neighborhood Hits	478	Shared Neighborhood Hits	263
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR25_HUMAN
θ value	2.56397e-71 (rank : 5)	NC score	0.934024 (rank : 3)
Query Neighborhood Hits	350	Target Neighborhood Hits	350	Shared Neighborhood Hits	249
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR38_HUMAN
θ value	1.66577e-62 (rank : 6)	NC score	0.909383 (rank : 6)
Query Neighborhood Hits	350	Target Neighborhood Hits	443	Shared Neighborhood Hits	238
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR38_MOUSE
θ value	1.55911e-60 (rank : 7)	NC score	0.883267 (rank : 7)
Query Neighborhood Hits	350	Target Neighborhood Hits	512	Shared Neighborhood Hits	238
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR50_HUMAN
θ value	6.85773e-16 (rank : 8)	NC score	0.800981 (rank : 11)
Query Neighborhood Hits	350	Target Neighborhood Hits	361	Shared Neighborhood Hits	264
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR29_HUMAN
θ value	4.16044e-13 (rank : 9)	NC score	0.818266 (rank : 8)
Query Neighborhood Hits	350	Target Neighborhood Hits	294	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

RAI14_HUMAN
θ value	2.0648e-12 (rank : 10)	NC score	0.602948 (rank : 179)
Query Neighborhood Hits	350	Target Neighborhood Hits	1367	Shared Neighborhood Hits	290
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

CSKI1_MOUSE
θ value	3.52202e-12 (rank : 11)	NC score	0.727878 (rank : 88)
Query Neighborhood Hits	350	Target Neighborhood Hits	1031	Shared Neighborhood Hits	273
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_HUMAN
θ value	4.59992e-12 (rank : 12)	NC score	0.729014 (rank : 85)
Query Neighborhood Hits	350	Target Neighborhood Hits	997	Shared Neighborhood Hits	270
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PSD10_HUMAN
θ value	4.59992e-12 (rank : 13)	NC score	0.804839 (rank : 9)
Query Neighborhood Hits	350	Target Neighborhood Hits	301	Shared Neighborhood Hits	262
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

RAI14_MOUSE
θ value	4.59992e-12 (rank : 14)	NC score	0.568907 (rank : 187)
Query Neighborhood Hits	350	Target Neighborhood Hits	1505	Shared Neighborhood Hits	295
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

PSD10_MOUSE
θ value	1.02475e-11 (rank : 15)	NC score	0.803353 (rank : 10)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	262
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
θ value	1.33837e-11 (rank : 16)	NC score	0.790950 (rank : 13)
Query Neighborhood Hits	350	Target Neighborhood Hits	439	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ASB2_HUMAN
θ value	2.28291e-11 (rank : 17)	NC score	0.772412 (rank : 30)
Query Neighborhood Hits	350	Target Neighborhood Hits	309	Shared Neighborhood Hits	261
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR28_HUMAN
θ value	2.98157e-11 (rank : 18)	NC score	0.767855 (rank : 32)
Query Neighborhood Hits	350	Target Neighborhood Hits	314	Shared Neighborhood Hits	262
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANKS3_MOUSE
θ value	3.89403e-11 (rank : 19)	NC score	0.780015 (rank : 18)
Query Neighborhood Hits	350	Target Neighborhood Hits	355	Shared Neighborhood Hits	260
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANFY1_MOUSE
θ value	6.64225e-11 (rank : 20)	NC score	0.700873 (rank : 117)
Query Neighborhood Hits	350	Target Neighborhood Hits	480	Shared Neighborhood Hits	261
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANK2_HUMAN
θ value	1.133e-10 (rank : 21)	NC score	0.706928 (rank : 110)
Query Neighborhood Hits	350	Target Neighborhood Hits	1615	Shared Neighborhood Hits	291
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR28_MOUSE
θ value	1.47974e-10 (rank : 22)	NC score	0.768463 (rank : 31)
Query Neighborhood Hits	350	Target Neighborhood Hits	314	Shared Neighborhood Hits	262
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANRA2_HUMAN
θ value	2.52405e-10 (rank : 23)	NC score	0.776807 (rank : 22)
Query Neighborhood Hits	350	Target Neighborhood Hits	288	Shared Neighborhood Hits	254
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

NOTC1_HUMAN
θ value	2.52405e-10 (rank : 24)	NC score	0.402301 (rank : 245)
Query Neighborhood Hits	350	Target Neighborhood Hits	906	Shared Neighborhood Hits	261
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

RIPK4_HUMAN
θ value	2.52405e-10 (rank : 25)	NC score	0.492768 (rank : 210)
Query Neighborhood Hits	350	Target Neighborhood Hits	1094	Shared Neighborhood Hits	267
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANK3_HUMAN
θ value	4.30538e-10 (rank : 26)	NC score	0.750146 (rank : 56)
Query Neighborhood Hits	350	Target Neighborhood Hits	853	Shared Neighborhood Hits	271
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

TNKS1_HUMAN
θ value	4.30538e-10 (rank : 27)	NC score	0.763929 (rank : 39)
Query Neighborhood Hits	350	Target Neighborhood Hits	477	Shared Neighborhood Hits	266
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
θ value	4.30538e-10 (rank : 28)	NC score	0.766197 (rank : 34)
Query Neighborhood Hits	350	Target Neighborhood Hits	361	Shared Neighborhood Hits	262
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

UACA_HUMAN
θ value	4.30538e-10 (rank : 29)	NC score	0.482586 (rank : 216)
Query Neighborhood Hits	350	Target Neighborhood Hits	1622	Shared Neighborhood Hits	296
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ASB2_MOUSE
θ value	5.62301e-10 (rank : 30)	NC score	0.765210 (rank : 36)
Query Neighborhood Hits	350	Target Neighborhood Hits	321	Shared Neighborhood Hits	261
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANKS1_HUMAN
θ value	7.34386e-10 (rank : 31)	NC score	0.745971 (rank : 62)
Query Neighborhood Hits	350	Target Neighborhood Hits	438	Shared Neighborhood Hits	263
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANRA2_MOUSE
θ value	9.59137e-10 (rank : 32)	NC score	0.776340 (rank : 25)
Query Neighborhood Hits	350	Target Neighborhood Hits	287	Shared Neighborhood Hits	255
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANFY1_HUMAN
θ value	1.25267e-09 (rank : 33)	NC score	0.698195 (rank : 118)
Query Neighborhood Hits	350	Target Neighborhood Hits	480	Shared Neighborhood Hits	262
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKS6_MOUSE
θ value	1.25267e-09 (rank : 34)	NC score	0.773805 (rank : 28)
Query Neighborhood Hits	350	Target Neighborhood Hits	435	Shared Neighborhood Hits	263
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

RN5A_MOUSE
θ value	1.25267e-09 (rank : 35)	NC score	0.697890 (rank : 119)
Query Neighborhood Hits	350	Target Neighborhood Hits	899	Shared Neighborhood Hits	264
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR35_HUMAN
θ value	1.63604e-09 (rank : 36)	NC score	0.725116 (rank : 95)
Query Neighborhood Hits	350	Target Neighborhood Hits	784	Shared Neighborhood Hits	280
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASZ1_HUMAN
θ value	1.63604e-09 (rank : 37)	NC score	0.775936 (rank : 27)
Query Neighborhood Hits	350	Target Neighborhood Hits	341	Shared Neighborhood Hits	253
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

DAPK1_HUMAN
θ value	2.13673e-09 (rank : 38)	NC score	0.350364 (rank : 259)
Query Neighborhood Hits	350	Target Neighborhood Hits	1130	Shared Neighborhood Hits	267
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

UACA_MOUSE
θ value	2.13673e-09 (rank : 39)	NC score	0.458086 (rank : 222)
Query Neighborhood Hits	350	Target Neighborhood Hits	1620	Shared Neighborhood Hits	291
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANKS3_HUMAN
θ value	2.79066e-09 (rank : 40)	NC score	0.776163 (rank : 26)
Query Neighborhood Hits	350	Target Neighborhood Hits	355	Shared Neighborhood Hits	263
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR16_HUMAN
θ value	2.79066e-09 (rank : 41)	NC score	0.794664 (rank : 12)
Query Neighborhood Hits	350	Target Neighborhood Hits	286	Shared Neighborhood Hits	258
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

MPP8_HUMAN
θ value	2.79066e-09 (rank : 42)	NC score	0.658591 (rank : 150)
Query Neighborhood Hits	350	Target Neighborhood Hits	948	Shared Neighborhood Hits	258
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NOTC2_HUMAN
θ value	2.79066e-09 (rank : 43)	NC score	0.400942 (rank : 247)
Query Neighborhood Hits	350	Target Neighborhood Hits	1113	Shared Neighborhood Hits	257
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANKK1_HUMAN
θ value	3.64472e-09 (rank : 44)	NC score	0.495784 (rank : 209)
Query Neighborhood Hits	350	Target Neighborhood Hits	1075	Shared Neighborhood Hits	267
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

EHMT1_HUMAN
θ value	3.64472e-09 (rank : 45)	NC score	0.721320 (rank : 99)
Query Neighborhood Hits	350	Target Neighborhood Hits	417	Shared Neighborhood Hits	264
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

CDN2C_MOUSE
θ value	4.76016e-09 (rank : 46)	NC score	0.781326 (rank : 17)
Query Neighborhood Hits	350	Target Neighborhood Hits	270	Shared Neighborhood Hits	249
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

NOTC3_HUMAN
θ value	4.76016e-09 (rank : 47)	NC score	0.403994 (rank : 244)
Query Neighborhood Hits	350	Target Neighborhood Hits	1062	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	4.76016e-09 (rank : 48)	NC score	0.406417 (rank : 242)
Query Neighborhood Hits	350	Target Neighborhood Hits	975	Shared Neighborhood Hits	256
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANK1_HUMAN
θ value	6.21693e-09 (rank : 49)	NC score	0.754680 (rank : 48)
Query Neighborhood Hits	350	Target Neighborhood Hits	416	Shared Neighborhood Hits	267
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	6.21693e-09 (rank : 50)	NC score	0.753792 (rank : 50)
Query Neighborhood Hits	350	Target Neighborhood Hits	430	Shared Neighborhood Hits	266
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

MIB1_HUMAN
θ value	6.21693e-09 (rank : 51)	NC score	0.745886 (rank : 63)
Query Neighborhood Hits	350	Target Neighborhood Hits	470	Shared Neighborhood Hits	261
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	6.21693e-09 (rank : 52)	NC score	0.745189 (rank : 65)
Query Neighborhood Hits	350	Target Neighborhood Hits	471	Shared Neighborhood Hits	260
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

DAPK1_MOUSE
θ value	8.11959e-09 (rank : 53)	NC score	0.357948 (rank : 257)
Query Neighborhood Hits	350	Target Neighborhood Hits	1138	Shared Neighborhood Hits	266
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

IKBA_MOUSE
θ value	8.11959e-09 (rank : 54)	NC score	0.747221 (rank : 59)
Query Neighborhood Hits	350	Target Neighborhood Hits	283	Shared Neighborhood Hits	252
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

MYPT1_HUMAN
θ value	8.11959e-09 (rank : 55)	NC score	0.728622 (rank : 86)
Query Neighborhood Hits	350	Target Neighborhood Hits	723	Shared Neighborhood Hits	276
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

NOTC2_MOUSE
θ value	8.11959e-09 (rank : 56)	NC score	0.397650 (rank : 250)
Query Neighborhood Hits	350	Target Neighborhood Hits	1069	Shared Neighborhood Hits	257
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANKS6_HUMAN
θ value	1.38499e-08 (rank : 57)	NC score	0.773749 (rank : 29)
Query Neighborhood Hits	350	Target Neighborhood Hits	411	Shared Neighborhood Hits	263
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ASZ1_MOUSE
θ value	1.38499e-08 (rank : 58)	NC score	0.779349 (rank : 20)
Query Neighborhood Hits	350	Target Neighborhood Hits	319	Shared Neighborhood Hits	255
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

BCL3_HUMAN
θ value	1.38499e-08 (rank : 59)	NC score	0.776671 (rank : 23)
Query Neighborhood Hits	350	Target Neighborhood Hits	324	Shared Neighborhood Hits	258
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ASB3_MOUSE
θ value	1.80886e-08 (rank : 60)	NC score	0.764067 (rank : 38)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	261
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

MIB2_HUMAN
θ value	1.80886e-08 (rank : 61)	NC score	0.729635 (rank : 84)
Query Neighborhood Hits	350	Target Neighborhood Hits	438	Shared Neighborhood Hits	260
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

NOTC1_MOUSE
θ value	1.80886e-08 (rank : 62)	NC score	0.353455 (rank : 258)
Query Neighborhood Hits	350	Target Neighborhood Hits	916	Shared Neighborhood Hits	243
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKK1_MOUSE
θ value	2.36244e-08 (rank : 63)	NC score	0.480220 (rank : 218)
Query Neighborhood Hits	350	Target Neighborhood Hits	1072	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR52_MOUSE
θ value	2.36244e-08 (rank : 64)	NC score	0.754899 (rank : 46)
Query Neighborhood Hits	350	Target Neighborhood Hits	318	Shared Neighborhood Hits	262
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

BCL3_MOUSE
θ value	2.36244e-08 (rank : 65)	NC score	0.776848 (rank : 21)
Query Neighborhood Hits	350	Target Neighborhood Hits	388	Shared Neighborhood Hits	259
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANR52_HUMAN
θ value	3.08544e-08 (rank : 66)	NC score	0.753724 (rank : 51)
Query Neighborhood Hits	350	Target Neighborhood Hits	322	Shared Neighborhood Hits	262
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

NOTC4_HUMAN
θ value	3.08544e-08 (rank : 67)	NC score	0.432908 (rank : 233)
Query Neighborhood Hits	350	Target Neighborhood Hits	905	Shared Neighborhood Hits	260
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	3.08544e-08 (rank : 68)	NC score	0.438639 (rank : 230)
Query Neighborhood Hits	350	Target Neighborhood Hits	872	Shared Neighborhood Hits	258
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

RN5A_HUMAN
θ value	3.08544e-08 (rank : 69)	NC score	0.746490 (rank : 60)
Query Neighborhood Hits	350	Target Neighborhood Hits	608	Shared Neighborhood Hits	259
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ACBD6_HUMAN
θ value	4.0297e-08 (rank : 70)	NC score	0.750981 (rank : 55)
Query Neighborhood Hits	350	Target Neighborhood Hits	304	Shared Neighborhood Hits	255
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

FANK1_MOUSE
θ value	4.0297e-08 (rank : 71)	NC score	0.784728 (rank : 15)
Query Neighborhood Hits	350	Target Neighborhood Hits	325	Shared Neighborhood Hits	258
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANR44_HUMAN
θ value	5.26297e-08 (rank : 72)	NC score	0.764290 (rank : 37)
Query Neighborhood Hits	350	Target Neighborhood Hits	318	Shared Neighborhood Hits	262
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ASB10_MOUSE
θ value	5.26297e-08 (rank : 73)	NC score	0.751286 (rank : 54)
Query Neighborhood Hits	350	Target Neighborhood Hits	301	Shared Neighborhood Hits	258
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

IKBA_HUMAN
θ value	5.26297e-08 (rank : 74)	NC score	0.753144 (rank : 52)
Query Neighborhood Hits	350	Target Neighborhood Hits	280	Shared Neighborhood Hits	254
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

MYPT1_MOUSE
θ value	5.26297e-08 (rank : 75)	NC score	0.739670 (rank : 68)
Query Neighborhood Hits	350	Target Neighborhood Hits	539	Shared Neighborhood Hits	269
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

TNI3K_MOUSE
θ value	5.26297e-08 (rank : 76)	NC score	0.383663 (rank : 254)
Query Neighborhood Hits	350	Target Neighborhood Hits	1079	Shared Neighborhood Hits	267
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

MYPT2_HUMAN
θ value	6.87365e-08 (rank : 77)	NC score	0.721481 (rank : 98)
Query Neighborhood Hits	350	Target Neighborhood Hits	707	Shared Neighborhood Hits	275
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

CTTB2_HUMAN
θ value	8.97725e-08 (rank : 78)	NC score	0.664507 (rank : 144)
Query Neighborhood Hits	350	Target Neighborhood Hits	1061	Shared Neighborhood Hits	288
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANKS1_MOUSE
θ value	1.17247e-07 (rank : 79)	NC score	0.731680 (rank : 80)
Query Neighborhood Hits	350	Target Neighborhood Hits	453	Shared Neighborhood Hits	265
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR21_HUMAN
θ value	1.17247e-07 (rank : 80)	NC score	0.682081 (rank : 134)
Query Neighborhood Hits	350	Target Neighborhood Hits	864	Shared Neighborhood Hits	280
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR26_MOUSE
θ value	1.17247e-07 (rank : 81)	NC score	0.429258 (rank : 235)
Query Neighborhood Hits	350	Target Neighborhood Hits	1554	Shared Neighborhood Hits	288
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

FANK1_HUMAN
θ value	1.17247e-07 (rank : 82)	NC score	0.786703 (rank : 14)
Query Neighborhood Hits	350	Target Neighborhood Hits	326	Shared Neighborhood Hits	258
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

AN30A_HUMAN
θ value	1.53129e-07 (rank : 83)	NC score	0.555219 (rank : 195)
Query Neighborhood Hits	350	Target Neighborhood Hits	1119	Shared Neighborhood Hits	279
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

INVS_HUMAN
θ value	1.53129e-07 (rank : 84)	NC score	0.767640 (rank : 33)
Query Neighborhood Hits	350	Target Neighborhood Hits	455	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	1.53129e-07 (rank : 85)	NC score	0.760317 (rank : 40)
Query Neighborhood Hits	350	Target Neighborhood Hits	609	Shared Neighborhood Hits	266
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

POT15_HUMAN
θ value	1.53129e-07 (rank : 86)	NC score	0.683491 (rank : 132)
Query Neighborhood Hits	350	Target Neighborhood Hits	893	Shared Neighborhood Hits	278
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

IKBE_MOUSE
θ value	1.99992e-07 (rank : 87)	NC score	0.739246 (rank : 71)
Query Neighborhood Hits	350	Target Neighborhood Hits	308	Shared Neighborhood Hits	254
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

CSKI2_HUMAN
θ value	2.61198e-07 (rank : 88)	NC score	0.711753 (rank : 108)
Query Neighborhood Hits	350	Target Neighborhood Hits	747	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CDN2C_HUMAN
θ value	3.41135e-07 (rank : 89)	NC score	0.776369 (rank : 24)
Query Neighborhood Hits	350	Target Neighborhood Hits	262	Shared Neighborhood Hits	244
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

EHMT2_MOUSE
θ value	3.41135e-07 (rank : 90)	NC score	0.693500 (rank : 123)
Query Neighborhood Hits	350	Target Neighborhood Hits	750	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB6_HUMAN
θ value	4.45536e-07 (rank : 91)	NC score	0.681940 (rank : 135)
Query Neighborhood Hits	350	Target Neighborhood Hits	256	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CSKI2_MOUSE
θ value	4.45536e-07 (rank : 92)	NC score	0.710610 (rank : 109)
Query Neighborhood Hits	350	Target Neighborhood Hits	812	Shared Neighborhood Hits	270
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

POTE8_HUMAN
θ value	4.45536e-07 (rank : 93)	NC score	0.722525 (rank : 97)
Query Neighborhood Hits	350	Target Neighborhood Hits	337	Shared Neighborhood Hits	258
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

AN36B_HUMAN
θ value	5.81887e-07 (rank : 94)	NC score	0.731968 (rank : 79)
Query Neighborhood Hits	350	Target Neighborhood Hits	294	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR39_HUMAN
θ value	5.81887e-07 (rank : 95)	NC score	0.783829 (rank : 16)
Query Neighborhood Hits	350	Target Neighborhood Hits	285	Shared Neighborhood Hits	256
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
θ value	5.81887e-07 (rank : 96)	NC score	0.779717 (rank : 19)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB3_HUMAN
θ value	5.81887e-07 (rank : 97)	NC score	0.765266 (rank : 35)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

EHMT2_HUMAN
θ value	5.81887e-07 (rank : 98)	NC score	0.704545 (rank : 114)
Query Neighborhood Hits	350	Target Neighborhood Hits	498	Shared Neighborhood Hits	267
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR12_HUMAN
θ value	9.92553e-07 (rank : 99)	NC score	0.636862 (rank : 160)
Query Neighborhood Hits	350	Target Neighborhood Hits	1081	Shared Neighborhood Hits	283
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR42_MOUSE
θ value	9.92553e-07 (rank : 100)	NC score	0.736163 (rank : 75)
Query Neighborhood Hits	350	Target Neighborhood Hits	334	Shared Neighborhood Hits	258
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANKR2_MOUSE
θ value	1.29631e-06 (rank : 101)	NC score	0.756790 (rank : 45)
Query Neighborhood Hits	350	Target Neighborhood Hits	312	Shared Neighborhood Hits	260
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

TNI3K_HUMAN
θ value	1.29631e-06 (rank : 102)	NC score	0.387213 (rank : 252)
Query Neighborhood Hits	350	Target Neighborhood Hits	1084	Shared Neighborhood Hits	267
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANR23_MOUSE
θ value	1.69304e-06 (rank : 103)	NC score	0.758923 (rank : 43)
Query Neighborhood Hits	350	Target Neighborhood Hits	296	Shared Neighborhood Hits	260
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

CENB5_HUMAN
θ value	1.69304e-06 (rank : 104)	NC score	0.489285 (rank : 213)
Query Neighborhood Hits	350	Target Neighborhood Hits	395	Shared Neighborhood Hits	247
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ANKR1_HUMAN
θ value	2.21117e-06 (rank : 105)	NC score	0.754128 (rank : 49)
Query Neighborhood Hits	350	Target Neighborhood Hits	308	Shared Neighborhood Hits	258
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ASB6_MOUSE
θ value	2.21117e-06 (rank : 106)	NC score	0.685328 (rank : 131)
Query Neighborhood Hits	350	Target Neighborhood Hits	264	Shared Neighborhood Hits	232
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ACBD6_MOUSE
θ value	2.88788e-06 (rank : 107)	NC score	0.745840 (rank : 64)
Query Neighborhood Hits	350	Target Neighborhood Hits	305	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASB10_HUMAN
θ value	2.88788e-06 (rank : 108)	NC score	0.743356 (rank : 66)
Query Neighborhood Hits	350	Target Neighborhood Hits	291	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB14_MOUSE
θ value	2.88788e-06 (rank : 109)	NC score	0.730843 (rank : 82)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	254
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

OSBL1_HUMAN
θ value	2.88788e-06 (rank : 110)	NC score	0.590486 (rank : 183)
Query Neighborhood Hits	350	Target Neighborhood Hits	368	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR23_HUMAN
θ value	3.77169e-06 (rank : 111)	NC score	0.759985 (rank : 41)
Query Neighborhood Hits	350	Target Neighborhood Hits	291	Shared Neighborhood Hits	259
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

NFKB1_HUMAN
θ value	3.77169e-06 (rank : 112)	NC score	0.667759 (rank : 141)
Query Neighborhood Hits	350	Target Neighborhood Hits	306	Shared Neighborhood Hits	256
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

RFXK_HUMAN
θ value	4.92598e-06 (rank : 113)	NC score	0.741315 (rank : 67)
Query Neighborhood Hits	350	Target Neighborhood Hits	282	Shared Neighborhood Hits	247
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

TRPA1_HUMAN
θ value	4.92598e-06 (rank : 114)	NC score	0.739632 (rank : 69)
Query Neighborhood Hits	350	Target Neighborhood Hits	339	Shared Neighborhood Hits	261
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANR33_MOUSE
θ value	6.43352e-06 (rank : 115)	NC score	0.727211 (rank : 93)
Query Neighborhood Hits	350	Target Neighborhood Hits	225	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

GABP3_MOUSE
θ value	6.43352e-06 (rank : 116)	NC score	0.752923 (rank : 53)
Query Neighborhood Hits	350	Target Neighborhood Hits	330	Shared Neighborhood Hits	258
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

SHAN1_HUMAN
θ value	6.43352e-06 (rank : 117)	NC score	0.623016 (rank : 172)
Query Neighborhood Hits	350	Target Neighborhood Hits	1041	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANKR2_HUMAN
θ value	8.40245e-06 (rank : 118)	NC score	0.754738 (rank : 47)
Query Neighborhood Hits	350	Target Neighborhood Hits	321	Shared Neighborhood Hits	260
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASB15_HUMAN
θ value	8.40245e-06 (rank : 119)	NC score	0.727722 (rank : 89)
Query Neighborhood Hits	350	Target Neighborhood Hits	305	Shared Neighborhood Hits	257
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANKR5_HUMAN
θ value	1.09739e-05 (rank : 120)	NC score	0.736880 (rank : 73)
Query Neighborhood Hits	350	Target Neighborhood Hits	297	Shared Neighborhood Hits	257
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR33_HUMAN
θ value	1.09739e-05 (rank : 121)	NC score	0.714623 (rank : 101)
Query Neighborhood Hits	350	Target Neighborhood Hits	215	Shared Neighborhood Hits	211
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

MIB2_MOUSE
θ value	1.09739e-05 (rank : 122)	NC score	0.726204 (rank : 94)
Query Neighborhood Hits	350	Target Neighborhood Hits	409	Shared Neighborhood Hits	259
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANKR1_MOUSE
θ value	1.43324e-05 (rank : 123)	NC score	0.746430 (rank : 61)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKR5_MOUSE
θ value	1.43324e-05 (rank : 124)	NC score	0.739260 (rank : 70)
Query Neighborhood Hits	350	Target Neighborhood Hits	298	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB7_HUMAN
θ value	1.43324e-05 (rank : 125)	NC score	0.749227 (rank : 58)
Query Neighborhood Hits	350	Target Neighborhood Hits	296	Shared Neighborhood Hits	259
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	1.43324e-05 (rank : 126)	NC score	0.749534 (rank : 57)
Query Neighborhood Hits	350	Target Neighborhood Hits	296	Shared Neighborhood Hits	259
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

BCOR_MOUSE
θ value	1.43324e-05 (rank : 127)	NC score	0.658718 (rank : 149)
Query Neighborhood Hits	350	Target Neighborhood Hits	521	Shared Neighborhood Hits	257
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

TRPA1_MOUSE
θ value	1.43324e-05 (rank : 128)	NC score	0.737094 (rank : 72)
Query Neighborhood Hits	350	Target Neighborhood Hits	343	Shared Neighborhood Hits	261
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

BCOR_HUMAN
θ value	1.87187e-05 (rank : 129)	NC score	0.651675 (rank : 154)
Query Neighborhood Hits	350	Target Neighborhood Hits	609	Shared Neighborhood Hits	257
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CDN2D_HUMAN
θ value	1.87187e-05 (rank : 130)	NC score	0.735902 (rank : 77)
Query Neighborhood Hits	350	Target Neighborhood Hits	268	Shared Neighborhood Hits	247
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

PA2G6_HUMAN
θ value	1.87187e-05 (rank : 131)	NC score	0.727681 (rank : 90)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	256
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PP16A_MOUSE
θ value	1.87187e-05 (rank : 132)	NC score	0.714621 (rank : 102)
Query Neighborhood Hits	350	Target Neighborhood Hits	318	Shared Neighborhood Hits	257
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2D_MOUSE
θ value	3.19293e-05 (rank : 133)	NC score	0.729815 (rank : 83)
Query Neighborhood Hits	350	Target Neighborhood Hits	267	Shared Neighborhood Hits	246
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

GABP2_MOUSE
θ value	3.19293e-05 (rank : 134)	NC score	0.759708 (rank : 42)
Query Neighborhood Hits	350	Target Neighborhood Hits	429	Shared Neighborhood Hits	260
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

RFXK_MOUSE
θ value	3.19293e-05 (rank : 135)	NC score	0.736315 (rank : 74)
Query Neighborhood Hits	350	Target Neighborhood Hits	273	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

DDFL1_MOUSE
θ value	4.1701e-05 (rank : 136)	NC score	0.433894 (rank : 232)
Query Neighborhood Hits	350	Target Neighborhood Hits	324	Shared Neighborhood Hits	240
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GABP2_HUMAN
θ value	4.1701e-05 (rank : 137)	NC score	0.757324 (rank : 44)
Query Neighborhood Hits	350	Target Neighborhood Hits	454	Shared Neighborhood Hits	261
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

POT14_HUMAN
θ value	4.1701e-05 (rank : 138)	NC score	0.667375 (rank : 142)
Query Neighborhood Hits	350	Target Neighborhood Hits	403	Shared Neighborhood Hits	258
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANKY2_HUMAN
θ value	5.44631e-05 (rank : 139)	NC score	0.694199 (rank : 122)
Query Neighborhood Hits	350	Target Neighborhood Hits	306	Shared Neighborhood Hits	242
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR42_HUMAN
θ value	5.44631e-05 (rank : 140)	NC score	0.731099 (rank : 81)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	257
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

POT22_HUMAN
θ value	5.44631e-05 (rank : 141)	NC score	0.633712 (rank : 163)
Query Neighborhood Hits	350	Target Neighborhood Hits	266	Shared Neighborhood Hits	244
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ZDH17_HUMAN
θ value	5.44631e-05 (rank : 142)	NC score	0.646338 (rank : 155)
Query Neighborhood Hits	350	Target Neighborhood Hits	334	Shared Neighborhood Hits	254
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANKY2_MOUSE
θ value	7.1131e-05 (rank : 143)	NC score	0.671549 (rank : 137)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	239
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASB12_MOUSE
θ value	7.1131e-05 (rank : 144)	NC score	0.694955 (rank : 120)
Query Neighborhood Hits	350	Target Neighborhood Hits	261	Shared Neighborhood Hits	245
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB15_MOUSE
θ value	7.1131e-05 (rank : 145)	NC score	0.714187 (rank : 103)
Query Neighborhood Hits	350	Target Neighborhood Hits	292	Shared Neighborhood Hits	251
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASPP2_HUMAN
θ value	7.1131e-05 (rank : 146)	NC score	0.511924 (rank : 204)
Query Neighborhood Hits	350	Target Neighborhood Hits	1156	Shared Neighborhood Hits	279
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANR19_HUMAN
θ value	9.29e-05 (rank : 147)	NC score	0.703694 (rank : 116)
Query Neighborhood Hits	350	Target Neighborhood Hits	276	Shared Neighborhood Hits	249
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ILK1_HUMAN
θ value	9.29e-05 (rank : 148)	NC score	0.445915 (rank : 226)
Query Neighborhood Hits	350	Target Neighborhood Hits	857	Shared Neighborhood Hits	262
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	9.29e-05 (rank : 149)	NC score	0.461615 (rank : 221)
Query Neighborhood Hits	350	Target Neighborhood Hits	848	Shared Neighborhood Hits	262
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

OSBL1_MOUSE
θ value	0.000121331 (rank : 150)	NC score	0.568384 (rank : 188)
Query Neighborhood Hits	350	Target Neighborhood Hits	336	Shared Neighborhood Hits	253
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ZDH17_MOUSE
θ value	0.000121331 (rank : 151)	NC score	0.638439 (rank : 159)
Query Neighborhood Hits	350	Target Neighborhood Hits	328	Shared Neighborhood Hits	253
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANR11_HUMAN
θ value	0.000158464 (rank : 152)	NC score	0.655819 (rank : 152)
Query Neighborhood Hits	350	Target Neighborhood Hits	1289	Shared Neighborhood Hits	285
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR46_HUMAN
θ value	0.000158464 (rank : 153)	NC score	0.727634 (rank : 91)
Query Neighborhood Hits	350	Target Neighborhood Hits	281	Shared Neighborhood Hits	249
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASB16_HUMAN
θ value	0.000158464 (rank : 154)	NC score	0.713602 (rank : 105)
Query Neighborhood Hits	350	Target Neighborhood Hits	286	Shared Neighborhood Hits	250
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANR46_MOUSE
θ value	0.00020696 (rank : 155)	NC score	0.712793 (rank : 106)
Query Neighborhood Hits	350	Target Neighborhood Hits	274	Shared Neighborhood Hits	245
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ILK_MOUSE
θ value	0.00020696 (rank : 156)	NC score	0.443122 (rank : 228)
Query Neighborhood Hits	350	Target Neighborhood Hits	858	Shared Neighborhood Hits	262
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ANR18_HUMAN
θ value	0.000270298 (rank : 157)	NC score	0.570300 (rank : 186)
Query Neighborhood Hits	350	Target Neighborhood Hits	1106	Shared Neighborhood Hits	273
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR43_HUMAN
θ value	0.000270298 (rank : 158)	NC score	0.566304 (rank : 189)
Query Neighborhood Hits	350	Target Neighborhood Hits	209	Shared Neighborhood Hits	195
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

PA2G6_MOUSE
θ value	0.000270298 (rank : 159)	NC score	0.728038 (rank : 87)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	259
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR45_MOUSE
θ value	0.00035302 (rank : 160)	NC score	0.549810 (rank : 196)
Query Neighborhood Hits	350	Target Neighborhood Hits	204	Shared Neighborhood Hits	182
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

IKBE_HUMAN
θ value	0.00035302 (rank : 161)	NC score	0.713700 (rank : 104)
Query Neighborhood Hits	350	Target Neighborhood Hits	288	Shared Neighborhood Hits	248
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANKY1_HUMAN
θ value	0.000461057 (rank : 162)	NC score	0.538938 (rank : 200)
Query Neighborhood Hits	350	Target Neighborhood Hits	248	Shared Neighborhood Hits	197
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

GFAP_MOUSE
θ value	0.000461057 (rank : 163)	NC score	0.037400 (rank : 354)
Query Neighborhood Hits	350	Target Neighborhood Hits	725	Shared Neighborhood Hits	43
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

ABTB2_MOUSE
θ value	0.000602161 (rank : 164)	NC score	0.504966 (rank : 205)
Query Neighborhood Hits	350	Target Neighborhood Hits	414	Shared Neighborhood Hits	226
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

OSTF1_MOUSE
θ value	0.000602161 (rank : 165)	NC score	0.582028 (rank : 185)
Query Neighborhood Hits	350	Target Neighborhood Hits	467	Shared Neighborhood Hits	237
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

PP16A_HUMAN
θ value	0.000602161 (rank : 166)	NC score	0.703698 (rank : 115)
Query Neighborhood Hits	350	Target Neighborhood Hits	340	Shared Neighborhood Hits	256
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR26_HUMAN
θ value	0.000786445 (rank : 167)	NC score	0.405126 (rank : 243)
Query Neighborhood Hits	350	Target Neighborhood Hits	1614	Shared Neighborhood Hits	289
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NFKB2_HUMAN
θ value	0.000786445 (rank : 168)	NC score	0.627016 (rank : 168)
Query Neighborhood Hits	350	Target Neighborhood Hits	325	Shared Neighborhood Hits	255
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ASB12_HUMAN
θ value	0.00102713 (rank : 169)	NC score	0.683282 (rank : 133)
Query Neighborhood Hits	350	Target Neighborhood Hits	263	Shared Neighborhood Hits	249
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB16_MOUSE
θ value	0.00134147 (rank : 170)	NC score	0.716958 (rank : 100)
Query Neighborhood Hits	350	Target Neighborhood Hits	306	Shared Neighborhood Hits	255
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

HECD1_HUMAN
θ value	0.00134147 (rank : 171)	NC score	0.546727 (rank : 197)
Query Neighborhood Hits	350	Target Neighborhood Hits	371	Shared Neighborhood Hits	251
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

NFKB1_MOUSE
θ value	0.00134147 (rank : 172)	NC score	0.652018 (rank : 153)
Query Neighborhood Hits	350	Target Neighborhood Hits	300	Shared Neighborhood Hits	250
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANR22_HUMAN
θ value	0.00175202 (rank : 173)	NC score	0.727427 (rank : 92)
Query Neighborhood Hits	350	Target Neighborhood Hits	243	Shared Neighborhood Hits	228
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR43_MOUSE
θ value	0.00175202 (rank : 174)	NC score	0.559970 (rank : 192)
Query Neighborhood Hits	350	Target Neighborhood Hits	214	Shared Neighborhood Hits	199
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ASPP1_HUMAN
θ value	0.00175202 (rank : 175)	NC score	0.481538 (rank : 217)
Query Neighborhood Hits	350	Target Neighborhood Hits	956	Shared Neighborhood Hits	270
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	0.00175202 (rank : 176)	NC score	0.467040 (rank : 220)
Query Neighborhood Hits	350	Target Neighborhood Hits	1244	Shared Neighborhood Hits	275
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

IKBB_MOUSE
θ value	0.00175202 (rank : 177)	NC score	0.694577 (rank : 121)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	254
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

TEX14_MOUSE
θ value	0.00175202 (rank : 178)	NC score	0.347609 (rank : 260)
Query Neighborhood Hits	350	Target Neighborhood Hits	1333	Shared Neighborhood Hits	260
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ZDH13_MOUSE
θ value	0.00175202 (rank : 179)	NC score	0.625516 (rank : 170)
Query Neighborhood Hits	350	Target Neighborhood Hits	329	Shared Neighborhood Hits	256
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANR45_HUMAN
θ value	0.00228821 (rank : 180)	NC score	0.513034 (rank : 203)
Query Neighborhood Hits	350	Target Neighborhood Hits	201	Shared Neighborhood Hits	177
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASB1_HUMAN
θ value	0.00228821 (rank : 181)	NC score	0.670095 (rank : 139)
Query Neighborhood Hits	350	Target Neighborhood Hits	291	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

GFAP_HUMAN
θ value	0.00228821 (rank : 182)	NC score	0.037493 (rank : 352)
Query Neighborhood Hits	350	Target Neighborhood Hits	723	Shared Neighborhood Hits	43
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

ZDH13_HUMAN
θ value	0.00298849 (rank : 183)	NC score	0.631474 (rank : 166)
Query Neighborhood Hits	350	Target Neighborhood Hits	322	Shared Neighborhood Hits	253
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANKR7_HUMAN
θ value	0.00390308 (rank : 184)	NC score	0.736025 (rank : 76)
Query Neighborhood Hits	350	Target Neighborhood Hits	286	Shared Neighborhood Hits	259
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR10_HUMAN
θ value	0.00390308 (rank : 185)	NC score	0.668951 (rank : 140)
Query Neighborhood Hits	350	Target Neighborhood Hits	289	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR37_MOUSE
θ value	0.00390308 (rank : 186)	NC score	0.621811 (rank : 173)
Query Neighborhood Hits	350	Target Neighborhood Hits	237	Shared Neighborhood Hits	222
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

BAT4_MOUSE
θ value	0.00390308 (rank : 187)	NC score	0.318342 (rank : 267)
Query Neighborhood Hits	350	Target Neighborhood Hits	171	Shared Neighborhood Hits	114
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CENB1_HUMAN
θ value	0.00390308 (rank : 188)	NC score	0.468617 (rank : 219)
Query Neighborhood Hits	350	Target Neighborhood Hits	383	Shared Neighborhood Hits	240
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ANS4B_HUMAN
θ value	0.00509761 (rank : 189)	NC score	0.644447 (rank : 156)
Query Neighborhood Hits	350	Target Neighborhood Hits	289	Shared Neighborhood Hits	244
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ASB1_MOUSE
θ value	0.00509761 (rank : 190)	NC score	0.662570 (rank : 148)
Query Neighborhood Hits	350	Target Neighborhood Hits	292	Shared Neighborhood Hits	251
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CENG2_HUMAN
θ value	0.00509761 (rank : 191)	NC score	0.320033 (rank : 265)
Query Neighborhood Hits	350	Target Neighborhood Hits	471	Shared Neighborhood Hits	242
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CT086_HUMAN
θ value	0.00509761 (rank : 192)	NC score	0.689262 (rank : 129)
Query Neighborhood Hits	350	Target Neighborhood Hits	277	Shared Neighborhood Hits	250
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

TRPV3_MOUSE
θ value	0.00509761 (rank : 193)	NC score	0.236916 (rank : 284)
Query Neighborhood Hits	350	Target Neighborhood Hits	188	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

AN36A_HUMAN
θ value	0.00665767 (rank : 194)	NC score	0.685992 (rank : 130)
Query Neighborhood Hits	350	Target Neighborhood Hits	271	Shared Neighborhood Hits	248
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANS4B_MOUSE
θ value	0.00665767 (rank : 195)	NC score	0.630362 (rank : 167)
Query Neighborhood Hits	350	Target Neighborhood Hits	294	Shared Neighborhood Hits	239
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

TRPV3_HUMAN
θ value	0.00665767 (rank : 196)	NC score	0.237096 (rank : 283)
Query Neighborhood Hits	350	Target Neighborhood Hits	198	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

IKBB_HUMAN
θ value	0.00869519 (rank : 197)	NC score	0.692147 (rank : 125)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

MTPN_MOUSE
θ value	0.00869519 (rank : 198)	NC score	0.732513 (rank : 78)
Query Neighborhood Hits	350	Target Neighborhood Hits	269	Shared Neighborhood Hits	252
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANR41_HUMAN
θ value	0.0113563 (rank : 199)	NC score	0.641643 (rank : 157)
Query Neighborhood Hits	350	Target Neighborhood Hits	332	Shared Neighborhood Hits	230
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

NUD12_MOUSE
θ value	0.0113563 (rank : 200)	NC score	0.544659 (rank : 199)
Query Neighborhood Hits	350	Target Neighborhood Hits	243	Shared Neighborhood Hits	213
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CENG2_MOUSE
θ value	0.0148317 (rank : 201)	NC score	0.320086 (rank : 264)
Query Neighborhood Hits	350	Target Neighborhood Hits	463	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

ANR10_MOUSE
θ value	0.0193708 (rank : 202)	NC score	0.663843 (rank : 145)
Query Neighborhood Hits	350	Target Neighborhood Hits	273	Shared Neighborhood Hits	247
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

BARD1_HUMAN
θ value	0.0193708 (rank : 203)	NC score	0.679217 (rank : 136)
Query Neighborhood Hits	350	Target Neighborhood Hits	427	Shared Neighborhood Hits	257
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	0.0193708 (rank : 204)	NC score	0.670218 (rank : 138)
Query Neighborhood Hits	350	Target Neighborhood Hits	411	Shared Neighborhood Hits	253
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BAT4_HUMAN
θ value	0.0193708 (rank : 205)	NC score	0.276779 (rank : 274)
Query Neighborhood Hits	350	Target Neighborhood Hits	157	Shared Neighborhood Hits	104
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

NFKB2_MOUSE
θ value	0.0193708 (rank : 206)	NC score	0.609841 (rank : 177)
Query Neighborhood Hits	350	Target Neighborhood Hits	326	Shared Neighborhood Hits	253
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

OSTF1_HUMAN
θ value	0.0193708 (rank : 207)	NC score	0.565585 (rank : 191)
Query Neighborhood Hits	350	Target Neighborhood Hits	466	Shared Neighborhood Hits	237
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

A20A1_HUMAN
θ value	0.0252991 (rank : 208)	NC score	0.592960 (rank : 182)
Query Neighborhood Hits	350	Target Neighborhood Hits	698	Shared Neighborhood Hits	274
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A3_HUMAN
θ value	0.0252991 (rank : 209)	NC score	0.594105 (rank : 180)
Query Neighborhood Hits	350	Target Neighborhood Hits	692	Shared Neighborhood Hits	276
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	0.0252991 (rank : 210)	NC score	0.590065 (rank : 184)
Query Neighborhood Hits	350	Target Neighborhood Hits	710	Shared Neighborhood Hits	276
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

MTPN_HUMAN
θ value	0.0252991 (rank : 211)	NC score	0.723979 (rank : 96)
Query Neighborhood Hits	350	Target Neighborhood Hits	269	Shared Neighborhood Hits	252
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

NUD12_HUMAN
θ value	0.0252991 (rank : 212)	NC score	0.523448 (rank : 201)
Query Neighborhood Hits	350	Target Neighborhood Hits	222	Shared Neighborhood Hits	195
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CLPB_HUMAN
θ value	0.0330416 (rank : 213)	NC score	0.546650 (rank : 198)
Query Neighborhood Hits	350	Target Neighborhood Hits	265	Shared Neighborhood Hits	219
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

PP16B_HUMAN
θ value	0.0330416 (rank : 214)	NC score	0.690647 (rank : 126)
Query Neighborhood Hits	350	Target Neighborhood Hits	307	Shared Neighborhood Hits	261
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

PP16B_MOUSE
θ value	0.0330416 (rank : 215)	NC score	0.690265 (rank : 128)
Query Neighborhood Hits	350	Target Neighborhood Hits	302	Shared Neighborhood Hits	261
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR32_HUMAN
θ value	0.0431538 (rank : 216)	NC score	0.665758 (rank : 143)
Query Neighborhood Hits	350	Target Neighborhood Hits	270	Shared Neighborhood Hits	245
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB4_MOUSE
θ value	0.0431538 (rank : 217)	NC score	0.662573 (rank : 147)
Query Neighborhood Hits	350	Target Neighborhood Hits	265	Shared Neighborhood Hits	246
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

A20A2_HUMAN
θ value	0.0563607 (rank : 218)	NC score	0.593343 (rank : 181)
Query Neighborhood Hits	350	Target Neighborhood Hits	716	Shared Neighborhood Hits	276
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANR32_MOUSE
θ value	0.0736092 (rank : 219)	NC score	0.658368 (rank : 151)
Query Neighborhood Hits	350	Target Neighborhood Hits	285	Shared Neighborhood Hits	245
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR49_MOUSE
θ value	0.0736092 (rank : 220)	NC score	0.712300 (rank : 107)
Query Neighborhood Hits	350	Target Neighborhood Hits	285	Shared Neighborhood Hits	258
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB8_MOUSE
θ value	0.0736092 (rank : 221)	NC score	0.706394 (rank : 111)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	254
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

AN13B_HUMAN
θ value	0.0961366 (rank : 222)	NC score	0.456571 (rank : 224)
Query Neighborhood Hits	350	Target Neighborhood Hits	265	Shared Neighborhood Hits	242
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

NRBF2_HUMAN
θ value	0.0961366 (rank : 223)	NC score	0.049000 (rank : 340)
Query Neighborhood Hits	350	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

TRPV6_MOUSE
θ value	0.0961366 (rank : 224)	NC score	0.489848 (rank : 212)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	236
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

AN13B_MOUSE
θ value	0.125558 (rank : 225)	NC score	0.457397 (rank : 223)
Query Neighborhood Hits	350	Target Neighborhood Hits	276	Shared Neighborhood Hits	244
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ASB11_MOUSE
θ value	0.125558 (rank : 226)	NC score	0.639911 (rank : 158)
Query Neighborhood Hits	350	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB4_HUMAN
θ value	0.125558 (rank : 227)	NC score	0.662945 (rank : 146)
Query Neighborhood Hits	350	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CLPB_MOUSE
θ value	0.125558 (rank : 228)	NC score	0.615755 (rank : 176)
Query Neighborhood Hits	350	Target Neighborhood Hits	289	Shared Neighborhood Hits	233
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

SYNE2_HUMAN
θ value	0.125558 (rank : 229)	NC score	0.040165 (rank : 348)
Query Neighborhood Hits	350	Target Neighborhood Hits	1323	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TEX14_HUMAN
θ value	0.125558 (rank : 230)	NC score	0.340611 (rank : 261)
Query Neighborhood Hits	350	Target Neighborhood Hits	1103	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ASB13_MOUSE
θ value	0.163984 (rank : 231)	NC score	0.692785 (rank : 124)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	255
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB8_HUMAN
θ value	0.163984 (rank : 232)	NC score	0.705446 (rank : 113)
Query Neighborhood Hits	350	Target Neighborhood Hits	294	Shared Neighborhood Hits	254
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

TRPV5_MOUSE
θ value	0.163984 (rank : 233)	NC score	0.442636 (rank : 229)
Query Neighborhood Hits	350	Target Neighborhood Hits	278	Shared Neighborhood Hits	229
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR49_HUMAN
θ value	0.21417 (rank : 234)	NC score	0.705974 (rank : 112)
Query Neighborhood Hits	350	Target Neighborhood Hits	282	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

KRIT1_HUMAN
θ value	0.21417 (rank : 235)	NC score	0.558469 (rank : 193)
Query Neighborhood Hits	350	Target Neighborhood Hits	258	Shared Neighborhood Hits	215
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

NIPBL_HUMAN
θ value	0.21417 (rank : 236)	NC score	0.035637 (rank : 356)
Query Neighborhood Hits	350	Target Neighborhood Hits	1311	Shared Neighborhood Hits	54
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SNCAP_HUMAN
θ value	0.21417 (rank : 237)	NC score	0.616508 (rank : 175)
Query Neighborhood Hits	350	Target Neighborhood Hits	313	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

AN13A_MOUSE
θ value	0.279714 (rank : 238)	NC score	0.380001 (rank : 256)
Query Neighborhood Hits	350	Target Neighborhood Hits	226	Shared Neighborhood Hits	207
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

ANR37_HUMAN
θ value	0.279714 (rank : 239)	NC score	0.621350 (rank : 174)
Query Neighborhood Hits	350	Target Neighborhood Hits	247	Shared Neighborhood Hits	229
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASB13_HUMAN
θ value	0.279714 (rank : 240)	NC score	0.690500 (rank : 127)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

NFM_HUMAN
θ value	0.279714 (rank : 241)	NC score	0.041499 (rank : 347)
Query Neighborhood Hits	350	Target Neighborhood Hits	1328	Shared Neighborhood Hits	73
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

ALEX_HUMAN
θ value	0.365318 (rank : 242)	NC score	0.038540 (rank : 350)
Query Neighborhood Hits	350	Target Neighborhood Hits	361	Shared Neighborhood Hits	15
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CAC1A_HUMAN
θ value	0.365318 (rank : 243)	NC score	0.006980 (rank : 402)
Query Neighborhood Hits	350	Target Neighborhood Hits	387	Shared Neighborhood Hits	13
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CCD41_MOUSE
θ value	0.365318 (rank : 244)	NC score	0.050460 (rank : 334)
Query Neighborhood Hits	350	Target Neighborhood Hits	1399	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CENG1_HUMAN
θ value	0.365318 (rank : 245)	NC score	0.301638 (rank : 270)
Query Neighborhood Hits	350	Target Neighborhood Hits	544	Shared Neighborhood Hits	230
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

RIMB1_MOUSE
θ value	0.365318 (rank : 246)	NC score	0.036293 (rank : 355)
Query Neighborhood Hits	350	Target Neighborhood Hits	1376	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

AN13A_HUMAN
θ value	0.47712 (rank : 247)	NC score	0.400308 (rank : 248)
Query Neighborhood Hits	350	Target Neighborhood Hits	243	Shared Neighborhood Hits	212
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

DDEF1_MOUSE
θ value	0.47712 (rank : 248)	NC score	0.246104 (rank : 282)
Query Neighborhood Hits	350	Target Neighborhood Hits	592	Shared Neighborhood Hits	189
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

IASPP_HUMAN
θ value	0.47712 (rank : 249)	NC score	0.490401 (rank : 211)
Query Neighborhood Hits	350	Target Neighborhood Hits	688	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

K1H4_HUMAN
θ value	0.47712 (rank : 250)	NC score	0.025078 (rank : 368)
Query Neighborhood Hits	350	Target Neighborhood Hits	476	Shared Neighborhood Hits	37
SwissProt Accessions	O76011	Gene names	KRTHA4, HHA4, HKA4
Domain Architecture
Description	Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4).

PDE4C_MOUSE
θ value	0.47712 (rank : 251)	NC score	0.007213 (rank : 401)
Query Neighborhood Hits	350	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

RP1L1_HUMAN
θ value	0.47712 (rank : 252)	NC score	0.043690 (rank : 345)
Query Neighborhood Hits	350	Target Neighborhood Hits	1072	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TRPV5_HUMAN
θ value	0.47712 (rank : 253)	NC score	0.425880 (rank : 237)
Query Neighborhood Hits	350	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
θ value	0.47712 (rank : 254)	NC score	0.416011 (rank : 240)
Query Neighborhood Hits	350	Target Neighborhood Hits	262	Shared Neighborhood Hits	211
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

DGKZ_HUMAN
θ value	0.62314 (rank : 255)	NC score	0.320548 (rank : 263)
Query Neighborhood Hits	350	Target Neighborhood Hits	551	Shared Neighborhood Hits	207
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

HIP1_HUMAN
θ value	0.62314 (rank : 256)	NC score	0.039523 (rank : 349)
Query Neighborhood Hits	350	Target Neighborhood Hits	1016	Shared Neighborhood Hits	53
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

LRRK1_MOUSE
θ value	0.62314 (rank : 257)	NC score	0.075068 (rank : 302)
Query Neighborhood Hits	350	Target Neighborhood Hits	1267	Shared Neighborhood Hits	120
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

NRBF2_MOUSE
θ value	0.62314 (rank : 258)	NC score	0.055762 (rank : 315)
Query Neighborhood Hits	350	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

P210L_HUMAN
θ value	0.62314 (rank : 259)	NC score	0.022830 (rank : 371)
Query Neighborhood Hits	350	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VU65, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6	Gene names	NUP210L
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

ABTB2_HUMAN
θ value	0.813845 (rank : 260)	NC score	0.496796 (rank : 207)
Query Neighborhood Hits	350	Target Neighborhood Hits	391	Shared Neighborhood Hits	226
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

B3A2_HUMAN
θ value	0.813845 (rank : 261)	NC score	0.007809 (rank : 399)
Query Neighborhood Hits	350	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

CENG1_MOUSE
θ value	0.813845 (rank : 262)	NC score	0.300115 (rank : 271)
Query Neighborhood Hits	350	Target Neighborhood Hits	531	Shared Neighborhood Hits	226
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

IASPP_MOUSE
θ value	0.813845 (rank : 263)	NC score	0.444223 (rank : 227)
Query Neighborhood Hits	350	Target Neighborhood Hits	1024	Shared Neighborhood Hits	256
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

P210L_MOUSE
θ value	0.813845 (rank : 264)	NC score	0.021107 (rank : 375)
Query Neighborhood Hits	350	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2F7	Gene names	Nup210l
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

RB6I2_HUMAN
θ value	0.813845 (rank : 265)	NC score	0.049392 (rank : 339)
Query Neighborhood Hits	350	Target Neighborhood Hits	1584	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

K1543_MOUSE
θ value	1.06291 (rank : 266)	NC score	0.035313 (rank : 357)
Query Neighborhood Hits	350	Target Neighborhood Hits	497	Shared Neighborhood Hits	26
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LMNB2_MOUSE
θ value	1.06291 (rank : 267)	NC score	0.034255 (rank : 359)
Query Neighborhood Hits	350	Target Neighborhood Hits	674	Shared Neighborhood Hits	41
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

USH1G_HUMAN
θ value	1.06291 (rank : 268)	NC score	0.632936 (rank : 164)
Query Neighborhood Hits	350	Target Neighborhood Hits	267	Shared Neighborhood Hits	243
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	1.06291 (rank : 269)	NC score	0.632561 (rank : 165)
Query Neighborhood Hits	350	Target Neighborhood Hits	271	Shared Neighborhood Hits	244
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ABL2_HUMAN
θ value	1.38821 (rank : 270)	NC score	0.010466 (rank : 393)
Query Neighborhood Hits	350	Target Neighborhood Hits	1045	Shared Neighborhood Hits	24
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ASB11_HUMAN
θ value	1.38821 (rank : 271)	NC score	0.634755 (rank : 162)
Query Neighborhood Hits	350	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

CEL_HUMAN
θ value	1.38821 (rank : 272)	NC score	0.014078 (rank : 385)
Query Neighborhood Hits	350	Target Neighborhood Hits	896	Shared Neighborhood Hits	29
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

DDFL1_HUMAN
θ value	1.38821 (rank : 273)	NC score	0.319796 (rank : 266)
Query Neighborhood Hits	350	Target Neighborhood Hits	353	Shared Neighborhood Hits	220
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDX18_MOUSE
θ value	1.38821 (rank : 274)	NC score	0.001464 (rank : 421)
Query Neighborhood Hits	350	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

HOME3_MOUSE
θ value	1.38821 (rank : 275)	NC score	0.028743 (rank : 364)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	28
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

LMNB2_HUMAN
θ value	1.38821 (rank : 276)	NC score	0.034002 (rank : 360)
Query Neighborhood Hits	350	Target Neighborhood Hits	723	Shared Neighborhood Hits	45
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

AKAP9_HUMAN
θ value	1.81305 (rank : 277)	NC score	0.049655 (rank : 338)
Query Neighborhood Hits	350	Target Neighborhood Hits	1710	Shared Neighborhood Hits	70
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANR40_HUMAN
θ value	1.81305 (rank : 278)	NC score	0.499623 (rank : 206)
Query Neighborhood Hits	350	Target Neighborhood Hits	224	Shared Neighborhood Hits	192
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	1.81305 (rank : 279)	NC score	0.496316 (rank : 208)
Query Neighborhood Hits	350	Target Neighborhood Hits	228	Shared Neighborhood Hits	195
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ARI1A_HUMAN
θ value	1.81305 (rank : 280)	NC score	0.025390 (rank : 366)
Query Neighborhood Hits	350	Target Neighborhood Hits	787	Shared Neighborhood Hits	35
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

FOXE2_HUMAN
θ value	1.81305 (rank : 281)	NC score	0.004068 (rank : 414)
Query Neighborhood Hits	350	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

GLSL_MOUSE
θ value	1.81305 (rank : 282)	NC score	0.426301 (rank : 236)
Query Neighborhood Hits	350	Target Neighborhood Hits	212	Shared Neighborhood Hits	192
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TLN1_HUMAN
θ value	1.81305 (rank : 283)	NC score	0.016052 (rank : 382)
Query Neighborhood Hits	350	Target Neighborhood Hits	218	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	1.81305 (rank : 284)	NC score	0.025116 (rank : 367)
Query Neighborhood Hits	350	Target Neighborhood Hits	213	Shared Neighborhood Hits	14
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

CENG3_HUMAN
θ value	2.36792 (rank : 285)	NC score	0.270451 (rank : 275)
Query Neighborhood Hits	350	Target Neighborhood Hits	455	Shared Neighborhood Hits	216
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	2.36792 (rank : 286)	NC score	0.270029 (rank : 276)
Query Neighborhood Hits	350	Target Neighborhood Hits	467	Shared Neighborhood Hits	215
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CF055_MOUSE
θ value	2.36792 (rank : 287)	NC score	0.015139 (rank : 384)
Query Neighborhood Hits	350	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

GIT1_HUMAN
θ value	2.36792 (rank : 288)	NC score	0.399541 (rank : 249)
Query Neighborhood Hits	350	Target Neighborhood Hits	336	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	2.36792 (rank : 289)	NC score	0.400984 (rank : 246)
Query Neighborhood Hits	350	Target Neighborhood Hits	341	Shared Neighborhood Hits	232
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

KCNQ1_MOUSE
θ value	2.36792 (rank : 290)	NC score	0.003211 (rank : 417)
Query Neighborhood Hits	350	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

SPTN5_HUMAN
θ value	2.36792 (rank : 291)	NC score	0.020126 (rank : 377)
Query Neighborhood Hits	350	Target Neighborhood Hits	674	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

IRS2_HUMAN
θ value	3.0926 (rank : 292)	NC score	0.016663 (rank : 380)
Query Neighborhood Hits	350	Target Neighborhood Hits	262	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

KI21A_MOUSE
θ value	3.0926 (rank : 293)	NC score	0.020195 (rank : 376)
Query Neighborhood Hits	350	Target Neighborhood Hits	1317	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KTN1_MOUSE
θ value	3.0926 (rank : 294)	NC score	0.046516 (rank : 341)
Query Neighborhood Hits	350	Target Neighborhood Hits	1324	Shared Neighborhood Hits	64
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MATK_HUMAN
θ value	3.0926 (rank : 295)	NC score	0.009955 (rank : 397)
Query Neighborhood Hits	350	Target Neighborhood Hits	954	Shared Neighborhood Hits	21
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MN1_HUMAN
θ value	3.0926 (rank : 296)	NC score	0.021119 (rank : 374)
Query Neighborhood Hits	350	Target Neighborhood Hits	196	Shared Neighborhood Hits	12
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

NCOA2_MOUSE
θ value	3.0926 (rank : 297)	NC score	0.005587 (rank : 406)
Query Neighborhood Hits	350	Target Neighborhood Hits	281	Shared Neighborhood Hits	10
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

TM16H_HUMAN
θ value	3.0926 (rank : 298)	NC score	0.012607 (rank : 388)
Query Neighborhood Hits	350	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

BIG2_HUMAN
θ value	4.03905 (rank : 299)	NC score	0.004705 (rank : 410)
Query Neighborhood Hits	350	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

CCD12_MOUSE
θ value	4.03905 (rank : 300)	NC score	0.030980 (rank : 362)
Query Neighborhood Hits	350	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R344, Q9CZH5	Gene names	Ccdc12
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 12.

EMSY_HUMAN
θ value	4.03905 (rank : 301)	NC score	0.010293 (rank : 395)
Query Neighborhood Hits	350	Target Neighborhood Hits	296	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

GLSL_HUMAN
θ value	4.03905 (rank : 302)	NC score	0.432163 (rank : 234)
Query Neighborhood Hits	350	Target Neighborhood Hits	211	Shared Neighborhood Hits	192
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GON4L_HUMAN
θ value	4.03905 (rank : 303)	NC score	0.017247 (rank : 379)
Query Neighborhood Hits	350	Target Neighborhood Hits	555	Shared Neighborhood Hits	28
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MAP1B_HUMAN
θ value	4.03905 (rank : 304)	NC score	0.031337 (rank : 361)
Query Neighborhood Hits	350	Target Neighborhood Hits	903	Shared Neighborhood Hits	45
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

PHLB1_HUMAN
θ value	4.03905 (rank : 305)	NC score	0.042818 (rank : 346)
Query Neighborhood Hits	350	Target Neighborhood Hits	1038	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	4.03905 (rank : 306)	NC score	0.029136 (rank : 363)
Query Neighborhood Hits	350	Target Neighborhood Hits	678	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RAI1_HUMAN
θ value	4.03905 (rank : 307)	NC score	0.010872 (rank : 390)
Query Neighborhood Hits	350	Target Neighborhood Hits	360	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAPSN_HUMAN
θ value	4.03905 (rank : 308)	NC score	0.016618 (rank : 381)
Query Neighborhood Hits	350	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

UBXD6_MOUSE
θ value	4.03905 (rank : 309)	NC score	0.013907 (rank : 386)
Query Neighborhood Hits	350	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ49	Gene names	Ubxd6, D0H8S2298E, Rep8
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 6 (Reproduction 8 protein) (Protein Rep- 8).

ZN445_HUMAN
θ value	4.03905 (rank : 310)	NC score	-0.011456 (rank : 422)
Query Neighborhood Hits	350	Target Neighborhood Hits	764	Shared Neighborhood Hits	5
SwissProt Accessions	P59923	Gene names	ZNF445, ZNF168
Domain Architecture
Description	Zinc finger protein 445.

AN13C_HUMAN
θ value	5.27518 (rank : 311)	NC score	0.422473 (rank : 238)
Query Neighborhood Hits	350	Target Neighborhood Hits	241	Shared Neighborhood Hits	223
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_MOUSE
θ value	5.27518 (rank : 312)	NC score	0.415494 (rank : 241)
Query Neighborhood Hits	350	Target Neighborhood Hits	242	Shared Neighborhood Hits	219
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ARVC_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.004579 (rank : 413)
Query Neighborhood Hits	350	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

B4GN3_HUMAN
θ value	5.27518 (rank : 314)	NC score	0.005899 (rank : 405)
Query Neighborhood Hits	350	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

CECR6_MOUSE
θ value	5.27518 (rank : 315)	NC score	0.010657 (rank : 392)
Query Neighborhood Hits	350	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

CHD6_HUMAN
θ value	5.27518 (rank : 316)	NC score	0.003343 (rank : 416)
Query Neighborhood Hits	350	Target Neighborhood Hits	342	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CTRO_MOUSE
θ value	5.27518 (rank : 317)	NC score	0.026880 (rank : 365)
Query Neighborhood Hits	350	Target Neighborhood Hits	2344	Shared Neighborhood Hits	82
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GIT2_MOUSE
θ value	5.27518 (rank : 318)	NC score	0.417851 (rank : 239)
Query Neighborhood Hits	350	Target Neighborhood Hits	323	Shared Neighborhood Hits	234
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

KIF17_MOUSE
θ value	5.27518 (rank : 319)	NC score	0.007314 (rank : 400)
Query Neighborhood Hits	350	Target Neighborhood Hits	452	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

LEO1_HUMAN
θ value	5.27518 (rank : 320)	NC score	0.021905 (rank : 372)
Query Neighborhood Hits	350	Target Neighborhood Hits	958	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MAGD4_HUMAN
θ value	5.27518 (rank : 321)	NC score	0.005376 (rank : 407)
Query Neighborhood Hits	350	Target Neighborhood Hits	338	Shared Neighborhood Hits	13
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MEIS2_MOUSE
θ value	5.27518 (rank : 322)	NC score	0.010309 (rank : 394)
Query Neighborhood Hits	350	Target Neighborhood Hits	208	Shared Neighborhood Hits	8
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

MYOC_HUMAN
θ value	5.27518 (rank : 323)	NC score	0.013895 (rank : 387)
Query Neighborhood Hits	350	Target Neighborhood Hits	489	Shared Neighborhood Hits	35
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

ASB5_HUMAN
θ value	6.88961 (rank : 324)	NC score	0.635389 (rank : 161)
Query Neighborhood Hits	350	Target Neighborhood Hits	283	Shared Neighborhood Hits	249
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

BNC2_HUMAN
θ value	6.88961 (rank : 325)	NC score	0.002552 (rank : 419)
Query Neighborhood Hits	350	Target Neighborhood Hits	439	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

CCD62_HUMAN
θ value	6.88961 (rank : 326)	NC score	0.035113 (rank : 358)
Query Neighborhood Hits	350	Target Neighborhood Hits	631	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CP250_MOUSE
θ value	6.88961 (rank : 327)	NC score	0.045173 (rank : 343)
Query Neighborhood Hits	350	Target Neighborhood Hits	1583	Shared Neighborhood Hits	70
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CTRO_HUMAN
θ value	6.88961 (rank : 328)	NC score	0.023854 (rank : 369)
Query Neighborhood Hits	350	Target Neighborhood Hits	2092	Shared Neighborhood Hits	71
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DC1L2_MOUSE
θ value	6.88961 (rank : 329)	NC score	0.006114 (rank : 404)
Query Neighborhood Hits	350	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

DCAK3_HUMAN
θ value	6.88961 (rank : 330)	NC score	0.003472 (rank : 415)
Query Neighborhood Hits	350	Target Neighborhood Hits	888	Shared Neighborhood Hits	21
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

GOGA3_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.045719 (rank : 342)
Query Neighborhood Hits	350	Target Neighborhood Hits	1437	Shared Neighborhood Hits	64
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MEIS2_HUMAN
θ value	6.88961 (rank : 332)	NC score	0.009071 (rank : 398)
Query Neighborhood Hits	350	Target Neighborhood Hits	182	Shared Neighborhood Hits	6
SwissProt Accessions	O14770, Q96KI4, Q96KI5, Q9NRS1, Q9NRS2, Q9NRS3	Gene names	MEIS2, MRG1
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

NASP_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.037465 (rank : 353)
Query Neighborhood Hits	350	Target Neighborhood Hits	709	Shared Neighborhood Hits	37
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

RAPSN_MOUSE
θ value	6.88961 (rank : 334)	NC score	0.015662 (rank : 383)
Query Neighborhood Hits	350	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

TULP2_HUMAN
θ value	6.88961 (rank : 335)	NC score	0.004607 (rank : 412)
Query Neighborhood Hits	350	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	O00295	Gene names	TULP2
Domain Architecture
Description	Tubby-related protein 2 (Tubby-like protein 2).

ZSWM5_MOUSE
θ value	6.88961 (rank : 336)	NC score	0.004858 (rank : 409)
Query Neighborhood Hits	350	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TC6	Gene names	Zswim5, Kiaa1511
Domain Architecture	No domain graphic available
Description	Zinc finger SWIM domain-containing protein 5.

ADNP_MOUSE
θ value	8.99809 (rank : 337)	NC score	0.010161 (rank : 396)
Query Neighborhood Hits	350	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z103	Gene names	Adnp
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

CABIN_HUMAN
θ value	8.99809 (rank : 338)	NC score	0.018507 (rank : 378)
Query Neighborhood Hits	350	Target Neighborhood Hits	490	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CENPE_HUMAN
θ value	8.99809 (rank : 339)	NC score	0.037709 (rank : 351)
Query Neighborhood Hits	350	Target Neighborhood Hits	2060	Shared Neighborhood Hits	75
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GCC1_MOUSE
θ value	8.99809 (rank : 340)	NC score	0.044469 (rank : 344)
Query Neighborhood Hits	350	Target Neighborhood Hits	777	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GLI3_MOUSE
θ value	8.99809 (rank : 341)	NC score	-0.011754 (rank : 423)
Query Neighborhood Hits	350	Target Neighborhood Hits	807	Shared Neighborhood Hits	5
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

GSCR2_HUMAN
θ value	8.99809 (rank : 342)	NC score	0.010762 (rank : 391)
Query Neighborhood Hits	350	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZM5, Q9BTC6, Q9HAX6, Q9NPP1, Q9NPR4, Q9UFI2	Gene names	GLTSCR2
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 2 protein (p60).

JARD2_MOUSE
θ value	8.99809 (rank : 343)	NC score	0.006302 (rank : 403)
Query Neighborhood Hits	350	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

LSD1_HUMAN
θ value	8.99809 (rank : 344)	NC score	0.021499 (rank : 373)
Query Neighborhood Hits	350	Target Neighborhood Hits	455	Shared Neighborhood Hits	29
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	8.99809 (rank : 345)	NC score	0.022907 (rank : 370)
Query Neighborhood Hits	350	Target Neighborhood Hits	224	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MYCB2_HUMAN
θ value	8.99809 (rank : 346)	NC score	0.005050 (rank : 408)
Query Neighborhood Hits	350	Target Neighborhood Hits	390	Shared Neighborhood Hits	14
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PDE9A_HUMAN
θ value	8.99809 (rank : 347)	NC score	0.002642 (rank : 418)
Query Neighborhood Hits	350	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PHC2_MOUSE
θ value	8.99809 (rank : 348)	NC score	0.004694 (rank : 411)
Query Neighborhood Hits	350	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PZP_HUMAN
θ value	8.99809 (rank : 349)	NC score	0.002152 (rank : 420)
Query Neighborhood Hits	350	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

SEPT9_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.011675 (rank : 389)
Query Neighborhood Hits	350	Target Neighborhood Hits	706	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ABTB1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.211291 (rank : 287)
Query Neighborhood Hits	350	Target Neighborhood Hits	325	Shared Neighborhood Hits	154
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.248839 (rank : 281)
Query Neighborhood Hits	350	Target Neighborhood Hits	349	Shared Neighborhood Hits	168
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ANKF1_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.118563 (rank : 297)
Query Neighborhood Hits	350	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.182912 (rank : 290)
Query Neighborhood Hits	350	Target Neighborhood Hits	99	Shared Neighborhood Hits	91
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.222763 (rank : 286)
Query Neighborhood Hits	350	Target Neighborhood Hits	120	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKZ1_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.259570 (rank : 279)
Query Neighborhood Hits	350	Target Neighborhood Hits	236	Shared Neighborhood Hits	148
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANKZ1_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.268492 (rank : 277)
Query Neighborhood Hits	350	Target Neighborhood Hits	208	Shared Neighborhood Hits	143
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ASB14_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.434499 (rank : 231)
Query Neighborhood Hits	350	Target Neighborhood Hits	187	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB5_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.625942 (rank : 169)
Query Neighborhood Hits	350	Target Neighborhood Hits	266	Shared Neighborhood Hits	240
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB9_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.623297 (rank : 171)
Query Neighborhood Hits	350	Target Neighborhood Hits	267	Shared Neighborhood Hits	240
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB9_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.609544 (rank : 178)
Query Neighborhood Hits	350	Target Neighborhood Hits	257	Shared Neighborhood Hits	237
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CD2A1_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.484035 (rank : 215)
Query Neighborhood Hits	350	Target Neighborhood Hits	196	Shared Neighborhood Hits	178
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CD2A1_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.557153 (rank : 194)
Query Neighborhood Hits	350	Target Neighborhood Hits	206	Shared Neighborhood Hits	188
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CDN2B_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.484760 (rank : 214)
Query Neighborhood Hits	350	Target Neighborhood Hits	196	Shared Neighborhood Hits	179
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CDN2B_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.516014 (rank : 202)
Query Neighborhood Hits	350	Target Neighborhood Hits	201	Shared Neighborhood Hits	184
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CENB2_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.449279 (rank : 225)
Query Neighborhood Hits	350	Target Neighborhood Hits	425	Shared Neighborhood Hits	245
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CLR59_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.236564 (rank : 285)
Query Neighborhood Hits	350	Target Neighborhood Hits	163	Shared Neighborhood Hits	135
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CMTA1_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.161586 (rank : 293)
Query Neighborhood Hits	350	Target Neighborhood Hits	217	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.122399 (rank : 296)
Query Neighborhood Hits	350	Target Neighborhood Hits	199	Shared Neighborhood Hits	82
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.112322 (rank : 298)
Query Neighborhood Hits	350	Target Neighborhood Hits	216	Shared Neighborhood Hits	74
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CRUM1_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.055431 (rank : 316)
Query Neighborhood Hits	350	Target Neighborhood Hits	457	Shared Neighborhood Hits	8
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.055184 (rank : 318)
Query Neighborhood Hits	350	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.056214 (rank : 314)
Query Neighborhood Hits	350	Target Neighborhood Hits	453	Shared Neighborhood Hits	8
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CT012_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.335545 (rank : 262)
Query Neighborhood Hits	350	Target Neighborhood Hits	205	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

CT012_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.383198 (rank : 255)
Query Neighborhood Hits	350	Target Neighborhood Hits	229	Shared Neighborhood Hits	164
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

CU081_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.066227 (rank : 303)
Query Neighborhood Hits	350	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DDEF2_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.315505 (rank : 268)
Query Neighborhood Hits	350	Target Neighborhood Hits	599	Shared Neighborhood Hits	229
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.315040 (rank : 269)
Query Neighborhood Hits	350	Target Neighborhood Hits	625	Shared Neighborhood Hits	232
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DGKI_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.278699 (rank : 273)
Query Neighborhood Hits	350	Target Neighborhood Hits	609	Shared Neighborhood Hits	205
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

DGKZ_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.290858 (rank : 272)
Query Neighborhood Hits	350	Target Neighborhood Hits	542	Shared Neighborhood Hits	193
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DLK_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.050190 (rank : 337)
Query Neighborhood Hits	350	Target Neighborhood Hits	374	Shared Neighborhood Hits	8
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.050987 (rank : 328)
Query Neighborhood Hits	350	Target Neighborhood Hits	419	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.052150 (rank : 323)
Query Neighborhood Hits	350	Target Neighborhood Hits	399	Shared Neighborhood Hits	8
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.050281 (rank : 335)
Query Neighborhood Hits	350	Target Neighborhood Hits	435	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.051287 (rank : 325)
Query Neighborhood Hits	350	Target Neighborhood Hits	440	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.056704 (rank : 313)
Query Neighborhood Hits	350	Target Neighborhood Hits	460	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.057566 (rank : 311)
Query Neighborhood Hits	350	Target Neighborhood Hits	413	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EGFL9_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.054081 (rank : 320)
Query Neighborhood Hits	350	Target Neighborhood Hits	365	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.053846 (rank : 321)
Query Neighborhood Hits	350	Target Neighborhood Hits	379	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FBN1_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.050708 (rank : 331)
Query Neighborhood Hits	350	Target Neighborhood Hits	557	Shared Neighborhood Hits	10
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.050826 (rank : 330)
Query Neighborhood Hits	350	Target Neighborhood Hits	563	Shared Neighborhood Hits	9
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.050989 (rank : 327)
Query Neighborhood Hits	350	Target Neighborhood Hits	560	Shared Neighborhood Hits	8
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.050833 (rank : 329)
Query Neighborhood Hits	350	Target Neighborhood Hits	549	Shared Neighborhood Hits	8
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.051467 (rank : 324)
Query Neighborhood Hits	350	Target Neighborhood Hits	543	Shared Neighborhood Hits	8
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GIT2_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.383994 (rank : 253)
Query Neighborhood Hits	350	Target Neighborhood Hits	381	Shared Neighborhood Hits	230
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GLSK_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.393230 (rank : 251)
Query Neighborhood Hits	350	Target Neighborhood Hits	204	Shared Neighborhood Hits	182
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

IKBL_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.264892 (rank : 278)
Query Neighborhood Hits	350	Target Neighborhood Hits	168	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.258197 (rank : 280)
Query Neighborhood Hits	350	Target Neighborhood Hits	196	Shared Neighborhood Hits	136
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

JAG1_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.057932 (rank : 308)
Query Neighborhood Hits	350	Target Neighborhood Hits	514	Shared Neighborhood Hits	8
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.057571 (rank : 310)
Query Neighborhood Hits	350	Target Neighborhood Hits	518	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.057914 (rank : 309)
Query Neighborhood Hits	350	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.058972 (rank : 306)
Query Neighborhood Hits	350	Target Neighborhood Hits	504	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR104_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.051175 (rank : 326)
Query Neighborhood Hits	350	Target Neighborhood Hits	313	Shared Neighborhood Hits	9
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRIT1_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.566146 (rank : 190)
Query Neighborhood Hits	350	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

KTN1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.050700 (rank : 332)
Query Neighborhood Hits	350	Target Neighborhood Hits	1197	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

LCE1B_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.058624 (rank : 307)
Query Neighborhood Hits	350	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.055344 (rank : 317)
Query Neighborhood Hits	350	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.054898 (rank : 319)
Query Neighborhood Hits	350	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LRRK1_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.050249 (rank : 336)
Query Neighborhood Hits	350	Target Neighborhood Hits	1237	Shared Neighborhood Hits	97
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MMRN1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.053565 (rank : 322)
Query Neighborhood Hits	350	Target Neighborhood Hits	636	Shared Neighborhood Hits	38
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

RSNL2_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.182177 (rank : 291)
Query Neighborhood Hits	350	Target Neighborhood Hits	136	Shared Neighborhood Hits	110
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.153061 (rank : 294)
Query Neighborhood Hits	350	Target Neighborhood Hits	129	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPC3_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.063774 (rank : 304)
Query Neighborhood Hits	350	Target Neighborhood Hits	137	Shared Neighborhood Hits	73
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC3_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.056986 (rank : 312)
Query Neighborhood Hits	350	Target Neighborhood Hits	131	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC5_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.050589 (rank : 333)
Query Neighborhood Hits	350	Target Neighborhood Hits	124	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC6_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.083434 (rank : 301)
Query Neighborhood Hits	350	Target Neighborhood Hits	171	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC6_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.059727 (rank : 305)
Query Neighborhood Hits	350	Target Neighborhood Hits	171	Shared Neighborhood Hits	82
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPV1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.188485 (rank : 289)
Query Neighborhood Hits	350	Target Neighborhood Hits	184	Shared Neighborhood Hits	138
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.201142 (rank : 288)
Query Neighborhood Hits	350	Target Neighborhood Hits	189	Shared Neighborhood Hits	145
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV2_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.169945 (rank : 292)
Query Neighborhood Hits	350	Target Neighborhood Hits	130	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.131461 (rank : 295)
Query Neighborhood Hits	350	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV4_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.106759 (rank : 299)
Query Neighborhood Hits	350	Target Neighborhood Hits	150	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.096912 (rank : 300)
Query Neighborhood Hits	350	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

Hits sorted by NC score

ANR47_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	350	Target Neighborhood Hits	350	Shared Neighborhood Hits	350
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR47_HUMAN
NC score	0.974803 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	350	Target Neighborhood Hits	369	Shared Neighborhood Hits	277
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR25_HUMAN
NC score	0.934024 (rank : 3)	θ value	2.56397e-71 (rank : 5)
Query Neighborhood Hits	350	Target Neighborhood Hits	350	Shared Neighborhood Hits	249
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR25_MOUSE
NC score	0.927085 (rank : 4)	θ value	5.86991e-92 (rank : 3)
Query Neighborhood Hits	350	Target Neighborhood Hits	398	Shared Neighborhood Hits	246
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR15_HUMAN
NC score	0.924891 (rank : 5)	θ value	5.33382e-77 (rank : 4)
Query Neighborhood Hits	350	Target Neighborhood Hits	478	Shared Neighborhood Hits	263
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR38_HUMAN
NC score	0.909383 (rank : 6)	θ value	1.66577e-62 (rank : 6)
Query Neighborhood Hits	350	Target Neighborhood Hits	443	Shared Neighborhood Hits	238
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR38_MOUSE
NC score	0.883267 (rank : 7)	θ value	1.55911e-60 (rank : 7)
Query Neighborhood Hits	350	Target Neighborhood Hits	512	Shared Neighborhood Hits	238
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR29_HUMAN
NC score	0.818266 (rank : 8)	θ value	4.16044e-13 (rank : 9)
Query Neighborhood Hits	350	Target Neighborhood Hits	294	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
NC score	0.804839 (rank : 9)	θ value	4.59992e-12 (rank : 13)
Query Neighborhood Hits	350	Target Neighborhood Hits	301	Shared Neighborhood Hits	262
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.803353 (rank : 10)	θ value	1.02475e-11 (rank : 15)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	262
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR50_HUMAN
NC score	0.800981 (rank : 11)	θ value	6.85773e-16 (rank : 8)
Query Neighborhood Hits	350	Target Neighborhood Hits	361	Shared Neighborhood Hits	264
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR16_HUMAN
NC score	0.794664 (rank : 12)	θ value	2.79066e-09 (rank : 41)
Query Neighborhood Hits	350	Target Neighborhood Hits	286	Shared Neighborhood Hits	258
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANKR6_HUMAN
NC score	0.790950 (rank : 13)	θ value	1.33837e-11 (rank : 16)
Query Neighborhood Hits	350	Target Neighborhood Hits	439	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

FANK1_HUMAN
NC score	0.786703 (rank : 14)	θ value	1.17247e-07 (rank : 82)
Query Neighborhood Hits	350	Target Neighborhood Hits	326	Shared Neighborhood Hits	258
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
NC score	0.784728 (rank : 15)	θ value	4.0297e-08 (rank : 71)
Query Neighborhood Hits	350	Target Neighborhood Hits	325	Shared Neighborhood Hits	258
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANR39_HUMAN
NC score	0.783829 (rank : 16)	θ value	5.81887e-07 (rank : 95)
Query Neighborhood Hits	350	Target Neighborhood Hits	285	Shared Neighborhood Hits	256
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

CDN2C_MOUSE
NC score	0.781326 (rank : 17)	θ value	4.76016e-09 (rank : 46)
Query Neighborhood Hits	350	Target Neighborhood Hits	270	Shared Neighborhood Hits	249
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANKS3_MOUSE
NC score	0.780015 (rank : 18)	θ value	3.89403e-11 (rank : 19)
Query Neighborhood Hits	350	Target Neighborhood Hits	355	Shared Neighborhood Hits	260
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR39_MOUSE
NC score	0.779717 (rank : 19)	θ value	5.81887e-07 (rank : 96)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASZ1_MOUSE
NC score	0.779349 (rank : 20)	θ value	1.38499e-08 (rank : 58)
Query Neighborhood Hits	350	Target Neighborhood Hits	319	Shared Neighborhood Hits	255
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

BCL3_MOUSE
NC score	0.776848 (rank : 21)	θ value	2.36244e-08 (rank : 65)
Query Neighborhood Hits	350	Target Neighborhood Hits	388	Shared Neighborhood Hits	259
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANRA2_HUMAN
NC score	0.776807 (rank : 22)	θ value	2.52405e-10 (rank : 23)
Query Neighborhood Hits	350	Target Neighborhood Hits	288	Shared Neighborhood Hits	254
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

BCL3_HUMAN
NC score	0.776671 (rank : 23)	θ value	1.38499e-08 (rank : 59)
Query Neighborhood Hits	350	Target Neighborhood Hits	324	Shared Neighborhood Hits	258
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

CDN2C_HUMAN
NC score	0.776369 (rank : 24)	θ value	3.41135e-07 (rank : 89)
Query Neighborhood Hits	350	Target Neighborhood Hits	262	Shared Neighborhood Hits	244
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANRA2_MOUSE
NC score	0.776340 (rank : 25)	θ value	9.59137e-10 (rank : 32)
Query Neighborhood Hits	350	Target Neighborhood Hits	287	Shared Neighborhood Hits	255
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANKS3_HUMAN
NC score	0.776163 (rank : 26)	θ value	2.79066e-09 (rank : 40)
Query Neighborhood Hits	350	Target Neighborhood Hits	355	Shared Neighborhood Hits	263
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASZ1_HUMAN
NC score	0.775936 (rank : 27)	θ value	1.63604e-09 (rank : 37)
Query Neighborhood Hits	350	Target Neighborhood Hits	341	Shared Neighborhood Hits	253
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKS6_MOUSE
NC score	0.773805 (rank : 28)	θ value	1.25267e-09 (rank : 34)
Query Neighborhood Hits	350	Target Neighborhood Hits	435	Shared Neighborhood Hits	263
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKS6_HUMAN
NC score	0.773749 (rank : 29)	θ value	1.38499e-08 (rank : 57)
Query Neighborhood Hits	350	Target Neighborhood Hits	411	Shared Neighborhood Hits	263
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ASB2_HUMAN
NC score	0.772412 (rank : 30)	θ value	2.28291e-11 (rank : 17)
Query Neighborhood Hits	350	Target Neighborhood Hits	309	Shared Neighborhood Hits	261
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR28_MOUSE
NC score	0.768463 (rank : 31)	θ value	1.47974e-10 (rank : 22)
Query Neighborhood Hits	350	Target Neighborhood Hits	314	Shared Neighborhood Hits	262
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
NC score	0.767855 (rank : 32)	θ value	2.98157e-11 (rank : 18)
Query Neighborhood Hits	350	Target Neighborhood Hits	314	Shared Neighborhood Hits	262
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

INVS_HUMAN
NC score	0.767640 (rank : 33)	θ value	1.53129e-07 (rank : 84)
Query Neighborhood Hits	350	Target Neighborhood Hits	455	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

TNKS2_HUMAN
NC score	0.766197 (rank : 34)	θ value	4.30538e-10 (rank : 28)
Query Neighborhood Hits	350	Target Neighborhood Hits	361	Shared Neighborhood Hits	262
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ASB3_HUMAN
NC score	0.765266 (rank : 35)	θ value	5.81887e-07 (rank : 97)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB2_MOUSE
NC score	0.765210 (rank : 36)	θ value	5.62301e-10 (rank : 30)
Query Neighborhood Hits	350	Target Neighborhood Hits	321	Shared Neighborhood Hits	261
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR44_HUMAN
NC score	0.764290 (rank : 37)	θ value	5.26297e-08 (rank : 72)
Query Neighborhood Hits	350	Target Neighborhood Hits	318	Shared Neighborhood Hits	262
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ASB3_MOUSE
NC score	0.764067 (rank : 38)	θ value	1.80886e-08 (rank : 60)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	261
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

TNKS1_HUMAN
NC score	0.763929 (rank : 39)	θ value	4.30538e-10 (rank : 27)
Query Neighborhood Hits	350	Target Neighborhood Hits	477	Shared Neighborhood Hits	266
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

INVS_MOUSE
NC score	0.760317 (rank : 40)	θ value	1.53129e-07 (rank : 85)
Query Neighborhood Hits	350	Target Neighborhood Hits	609	Shared Neighborhood Hits	266
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR23_HUMAN
NC score	0.759985 (rank : 41)	θ value	3.77169e-06 (rank : 111)
Query Neighborhood Hits	350	Target Neighborhood Hits	291	Shared Neighborhood Hits	259
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

GABP2_MOUSE
NC score	0.759708 (rank : 42)	θ value	3.19293e-05 (rank : 134)
Query Neighborhood Hits	350	Target Neighborhood Hits	429	Shared Neighborhood Hits	260
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANR23_MOUSE
NC score	0.758923 (rank : 43)	θ value	1.69304e-06 (rank : 103)
Query Neighborhood Hits	350	Target Neighborhood Hits	296	Shared Neighborhood Hits	260
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

GABP2_HUMAN
NC score	0.757324 (rank : 44)	θ value	4.1701e-05 (rank : 137)
Query Neighborhood Hits	350	Target Neighborhood Hits	454	Shared Neighborhood Hits	261
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ANKR2_MOUSE
NC score	0.756790 (rank : 45)	θ value	1.29631e-06 (rank : 101)
Query Neighborhood Hits	350	Target Neighborhood Hits	312	Shared Neighborhood Hits	260
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR52_MOUSE
NC score	0.754899 (rank : 46)	θ value	2.36244e-08 (rank : 64)
Query Neighborhood Hits	350	Target Neighborhood Hits	318	Shared Neighborhood Hits	262
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANKR2_HUMAN
NC score	0.754738 (rank : 47)	θ value	8.40245e-06 (rank : 118)
Query Neighborhood Hits	350	Target Neighborhood Hits	321	Shared Neighborhood Hits	260
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANK1_HUMAN
NC score	0.754680 (rank : 48)	θ value	6.21693e-09 (rank : 49)
Query Neighborhood Hits	350	Target Neighborhood Hits	416	Shared Neighborhood Hits	267
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANKR1_HUMAN
NC score	0.754128 (rank : 49)	θ value	2.21117e-06 (rank : 105)
Query Neighborhood Hits	350	Target Neighborhood Hits	308	Shared Neighborhood Hits	258
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANK1_MOUSE
NC score	0.753792 (rank : 50)	θ value	6.21693e-09 (rank : 50)
Query Neighborhood Hits	350	Target Neighborhood Hits	430	Shared Neighborhood Hits	266
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR52_HUMAN
NC score	0.753724 (rank : 51)	θ value	3.08544e-08 (rank : 66)
Query Neighborhood Hits	350	Target Neighborhood Hits	322	Shared Neighborhood Hits	262
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

IKBA_HUMAN
NC score	0.753144 (rank : 52)	θ value	5.26297e-08 (rank : 74)
Query Neighborhood Hits	350	Target Neighborhood Hits	280	Shared Neighborhood Hits	254
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

GABP3_MOUSE
NC score	0.752923 (rank : 53)	θ value	6.43352e-06 (rank : 116)
Query Neighborhood Hits	350	Target Neighborhood Hits	330	Shared Neighborhood Hits	258
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ASB10_MOUSE
NC score	0.751286 (rank : 54)	θ value	5.26297e-08 (rank : 73)
Query Neighborhood Hits	350	Target Neighborhood Hits	301	Shared Neighborhood Hits	258
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ACBD6_HUMAN
NC score	0.750981 (rank : 55)	θ value	4.0297e-08 (rank : 70)
Query Neighborhood Hits	350	Target Neighborhood Hits	304	Shared Neighborhood Hits	255
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANK3_HUMAN
NC score	0.750146 (rank : 56)	θ value	4.30538e-10 (rank : 26)
Query Neighborhood Hits	350	Target Neighborhood Hits	853	Shared Neighborhood Hits	271
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ASB7_MOUSE
NC score	0.749534 (rank : 57)	θ value	1.43324e-05 (rank : 126)
Query Neighborhood Hits	350	Target Neighborhood Hits	296	Shared Neighborhood Hits	259
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.749227 (rank : 58)	θ value	1.43324e-05 (rank : 125)
Query Neighborhood Hits	350	Target Neighborhood Hits	296	Shared Neighborhood Hits	259
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

IKBA_MOUSE
NC score	0.747221 (rank : 59)	θ value	8.11959e-09 (rank : 54)
Query Neighborhood Hits	350	Target Neighborhood Hits	283	Shared Neighborhood Hits	252
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

RN5A_HUMAN
NC score	0.746490 (rank : 60)	θ value	3.08544e-08 (rank : 69)
Query Neighborhood Hits	350	Target Neighborhood Hits	608	Shared Neighborhood Hits	259
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANKR1_MOUSE
NC score	0.746430 (rank : 61)	θ value	1.43324e-05 (rank : 123)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKS1_HUMAN
NC score	0.745971 (rank : 62)	θ value	7.34386e-10 (rank : 31)
Query Neighborhood Hits	350	Target Neighborhood Hits	438	Shared Neighborhood Hits	263
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

MIB1_HUMAN
NC score	0.745886 (rank : 63)	θ value	6.21693e-09 (rank : 51)
Query Neighborhood Hits	350	Target Neighborhood Hits	470	Shared Neighborhood Hits	261
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

ACBD6_MOUSE
NC score	0.745840 (rank : 64)	θ value	2.88788e-06 (rank : 107)
Query Neighborhood Hits	350	Target Neighborhood Hits	305	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

MIB1_MOUSE
NC score	0.745189 (rank : 65)	θ value	6.21693e-09 (rank : 52)
Query Neighborhood Hits	350	Target Neighborhood Hits	471	Shared Neighborhood Hits	260
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ASB10_HUMAN
NC score	0.743356 (rank : 66)	θ value	2.88788e-06 (rank : 108)
Query Neighborhood Hits	350	Target Neighborhood Hits	291	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

RFXK_HUMAN
NC score	0.741315 (rank : 67)	θ value	4.92598e-06 (rank : 113)
Query Neighborhood Hits	350	Target Neighborhood Hits	282	Shared Neighborhood Hits	247
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

MYPT1_MOUSE
NC score	0.739670 (rank : 68)	θ value	5.26297e-08 (rank : 75)
Query Neighborhood Hits	350	Target Neighborhood Hits	539	Shared Neighborhood Hits	269
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

TRPA1_HUMAN
NC score	0.739632 (rank : 69)	θ value	4.92598e-06 (rank : 114)
Query Neighborhood Hits	350	Target Neighborhood Hits	339	Shared Neighborhood Hits	261
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANKR5_MOUSE
NC score	0.739260 (rank : 70)	θ value	1.43324e-05 (rank : 124)
Query Neighborhood Hits	350	Target Neighborhood Hits	298	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

IKBE_MOUSE
NC score	0.739246 (rank : 71)	θ value	1.99992e-07 (rank : 87)
Query Neighborhood Hits	350	Target Neighborhood Hits	308	Shared Neighborhood Hits	254
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

TRPA1_MOUSE
NC score	0.737094 (rank : 72)	θ value	1.43324e-05 (rank : 128)
Query Neighborhood Hits	350	Target Neighborhood Hits	343	Shared Neighborhood Hits	261
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANKR5_HUMAN
NC score	0.736880 (rank : 73)	θ value	1.09739e-05 (rank : 120)
Query Neighborhood Hits	350	Target Neighborhood Hits	297	Shared Neighborhood Hits	257
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

RFXK_MOUSE
NC score	0.736315 (rank : 74)	θ value	3.19293e-05 (rank : 135)
Query Neighborhood Hits	350	Target Neighborhood Hits	273	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ANR42_MOUSE
NC score	0.736163 (rank : 75)	θ value	9.92553e-07 (rank : 100)
Query Neighborhood Hits	350	Target Neighborhood Hits	334	Shared Neighborhood Hits	258
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANKR7_HUMAN
NC score	0.736025 (rank : 76)	θ value	0.00390308 (rank : 184)
Query Neighborhood Hits	350	Target Neighborhood Hits	286	Shared Neighborhood Hits	259
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

CDN2D_HUMAN
NC score	0.735902 (rank : 77)	θ value	1.87187e-05 (rank : 130)
Query Neighborhood Hits	350	Target Neighborhood Hits	268	Shared Neighborhood Hits	247
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

MTPN_MOUSE
NC score	0.732513 (rank : 78)	θ value	0.00869519 (rank : 198)
Query Neighborhood Hits	350	Target Neighborhood Hits	269	Shared Neighborhood Hits	252
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

AN36B_HUMAN
NC score	0.731968 (rank : 79)	θ value	5.81887e-07 (rank : 94)
Query Neighborhood Hits	350	Target Neighborhood Hits	294	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANKS1_MOUSE
NC score	0.731680 (rank : 80)	θ value	1.17247e-07 (rank : 79)
Query Neighborhood Hits	350	Target Neighborhood Hits	453	Shared Neighborhood Hits	265
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR42_HUMAN
NC score	0.731099 (rank : 81)	θ value	5.44631e-05 (rank : 140)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	257
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB14_MOUSE
NC score	0.730843 (rank : 82)	θ value	2.88788e-06 (rank : 109)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	254
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CDN2D_MOUSE
NC score	0.729815 (rank : 83)	θ value	3.19293e-05 (rank : 133)
Query Neighborhood Hits	350	Target Neighborhood Hits	267	Shared Neighborhood Hits	246
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

MIB2_HUMAN
NC score	0.729635 (rank : 84)	θ value	1.80886e-08 (rank : 61)
Query Neighborhood Hits	350	Target Neighborhood Hits	438	Shared Neighborhood Hits	260
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CSKI1_HUMAN
NC score	0.729014 (rank : 85)	θ value	4.59992e-12 (rank : 12)
Query Neighborhood Hits	350	Target Neighborhood Hits	997	Shared Neighborhood Hits	270
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYPT1_HUMAN
NC score	0.728622 (rank : 86)	θ value	8.11959e-09 (rank : 55)
Query Neighborhood Hits	350	Target Neighborhood Hits	723	Shared Neighborhood Hits	276
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

PA2G6_MOUSE
NC score	0.728038 (rank : 87)	θ value	0.000270298 (rank : 159)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	259
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

CSKI1_MOUSE
NC score	0.727878 (rank : 88)	θ value	3.52202e-12 (rank : 11)
Query Neighborhood Hits	350	Target Neighborhood Hits	1031	Shared Neighborhood Hits	273
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ASB15_HUMAN
NC score	0.727722 (rank : 89)	θ value	8.40245e-06 (rank : 119)
Query Neighborhood Hits	350	Target Neighborhood Hits	305	Shared Neighborhood Hits	257
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

PA2G6_HUMAN
NC score	0.727681 (rank : 90)	θ value	1.87187e-05 (rank : 131)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	256
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR46_HUMAN
NC score	0.727634 (rank : 91)	θ value	0.000158464 (rank : 153)
Query Neighborhood Hits	350	Target Neighborhood Hits	281	Shared Neighborhood Hits	249
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR22_HUMAN
NC score	0.727427 (rank : 92)	θ value	0.00175202 (rank : 173)
Query Neighborhood Hits	350	Target Neighborhood Hits	243	Shared Neighborhood Hits	228
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR33_MOUSE
NC score	0.727211 (rank : 93)	θ value	6.43352e-06 (rank : 115)
Query Neighborhood Hits	350	Target Neighborhood Hits	225	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

MIB2_MOUSE
NC score	0.726204 (rank : 94)	θ value	1.09739e-05 (rank : 122)
Query Neighborhood Hits	350	Target Neighborhood Hits	409	Shared Neighborhood Hits	259
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANR35_HUMAN
NC score	0.725116 (rank : 95)	θ value	1.63604e-09 (rank : 36)
Query Neighborhood Hits	350	Target Neighborhood Hits	784	Shared Neighborhood Hits	280
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

MTPN_HUMAN
NC score	0.723979 (rank : 96)	θ value	0.0252991 (rank : 211)
Query Neighborhood Hits	350	Target Neighborhood Hits	269	Shared Neighborhood Hits	252
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

POTE8_HUMAN
NC score	0.722525 (rank : 97)	θ value	4.45536e-07 (rank : 93)
Query Neighborhood Hits	350	Target Neighborhood Hits	337	Shared Neighborhood Hits	258
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

MYPT2_HUMAN
NC score	0.721481 (rank : 98)	θ value	6.87365e-08 (rank : 77)
Query Neighborhood Hits	350	Target Neighborhood Hits	707	Shared Neighborhood Hits	275
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

EHMT1_HUMAN
NC score	0.721320 (rank : 99)	θ value	3.64472e-09 (rank : 45)
Query Neighborhood Hits	350	Target Neighborhood Hits	417	Shared Neighborhood Hits	264
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ASB16_MOUSE
NC score	0.716958 (rank : 100)	θ value	0.00134147 (rank : 170)
Query Neighborhood Hits	350	Target Neighborhood Hits	306	Shared Neighborhood Hits	255
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANR33_HUMAN
NC score	0.714623 (rank : 101)	θ value	1.09739e-05 (rank : 121)
Query Neighborhood Hits	350	Target Neighborhood Hits	215	Shared Neighborhood Hits	211
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

PP16A_MOUSE
NC score	0.714621 (rank : 102)	θ value	1.87187e-05 (rank : 132)
Query Neighborhood Hits	350	Target Neighborhood Hits	318	Shared Neighborhood Hits	257
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ASB15_MOUSE
NC score	0.714187 (rank : 103)	θ value	7.1131e-05 (rank : 145)
Query Neighborhood Hits	350	Target Neighborhood Hits	292	Shared Neighborhood Hits	251
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

IKBE_HUMAN
NC score	0.713700 (rank : 104)	θ value	0.00035302 (rank : 161)
Query Neighborhood Hits	350	Target Neighborhood Hits	288	Shared Neighborhood Hits	248
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ASB16_HUMAN
NC score	0.713602 (rank : 105)	θ value	0.000158464 (rank : 154)
Query Neighborhood Hits	350	Target Neighborhood Hits	286	Shared Neighborhood Hits	250
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANR46_MOUSE
NC score	0.712793 (rank : 106)	θ value	0.00020696 (rank : 155)
Query Neighborhood Hits	350	Target Neighborhood Hits	274	Shared Neighborhood Hits	245
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR49_MOUSE
NC score	0.712300 (rank : 107)	θ value	0.0736092 (rank : 220)
Query Neighborhood Hits	350	Target Neighborhood Hits	285	Shared Neighborhood Hits	258
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

CSKI2_HUMAN
NC score	0.711753 (rank : 108)	θ value	2.61198e-07 (rank : 88)
Query Neighborhood Hits	350	Target Neighborhood Hits	747	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
NC score	0.710610 (rank : 109)	θ value	4.45536e-07 (rank : 92)
Query Neighborhood Hits	350	Target Neighborhood Hits	812	Shared Neighborhood Hits	270
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANK2_HUMAN
NC score	0.706928 (rank : 110)	θ value	1.133e-10 (rank : 21)
Query Neighborhood Hits	350	Target Neighborhood Hits	1615	Shared Neighborhood Hits	291
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASB8_MOUSE
NC score	0.706394 (rank : 111)	θ value	0.0736092 (rank : 221)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	254
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR49_HUMAN
NC score	0.705974 (rank : 112)	θ value	0.21417 (rank : 234)
Query Neighborhood Hits	350	Target Neighborhood Hits	282	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASB8_HUMAN
NC score	0.705446 (rank : 113)	θ value	0.163984 (rank : 232)
Query Neighborhood Hits	350	Target Neighborhood Hits	294	Shared Neighborhood Hits	254
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

EHMT2_HUMAN
NC score	0.704545 (rank : 114)	θ value	5.81887e-07 (rank : 98)
Query Neighborhood Hits	350	Target Neighborhood Hits	498	Shared Neighborhood Hits	267
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PP16A_HUMAN
NC score	0.703698 (rank : 115)	θ value	0.000602161 (rank : 166)
Query Neighborhood Hits	350	Target Neighborhood Hits	340	Shared Neighborhood Hits	256
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR19_HUMAN
NC score	0.703694 (rank : 116)	θ value	9.29e-05 (rank : 147)
Query Neighborhood Hits	350	Target Neighborhood Hits	276	Shared Neighborhood Hits	249
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANFY1_MOUSE
NC score	0.700873 (rank : 117)	θ value	6.64225e-11 (rank : 20)
Query Neighborhood Hits	350	Target Neighborhood Hits	480	Shared Neighborhood Hits	261
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.698195 (rank : 118)	θ value	1.25267e-09 (rank : 33)
Query Neighborhood Hits	350	Target Neighborhood Hits	480	Shared Neighborhood Hits	262
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

RN5A_MOUSE
NC score	0.697890 (rank : 119)	θ value	1.25267e-09 (rank : 35)
Query Neighborhood Hits	350	Target Neighborhood Hits	899	Shared Neighborhood Hits	264
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB12_MOUSE
NC score	0.694955 (rank : 120)	θ value	7.1131e-05 (rank : 144)
Query Neighborhood Hits	350	Target Neighborhood Hits	261	Shared Neighborhood Hits	245
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

IKBB_MOUSE
NC score	0.694577 (rank : 121)	θ value	0.00175202 (rank : 177)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	254
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANKY2_HUMAN
NC score	0.694199 (rank : 122)	θ value	5.44631e-05 (rank : 139)
Query Neighborhood Hits	350	Target Neighborhood Hits	306	Shared Neighborhood Hits	242
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

EHMT2_MOUSE
NC score	0.693500 (rank : 123)	θ value	3.41135e-07 (rank : 90)
Query Neighborhood Hits	350	Target Neighborhood Hits	750	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB13_MOUSE
NC score	0.692785 (rank : 124)	θ value	0.163984 (rank : 231)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	255
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

IKBB_HUMAN
NC score	0.692147 (rank : 125)	θ value	0.00869519 (rank : 197)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

PP16B_HUMAN
NC score	0.690647 (rank : 126)	θ value	0.0330416 (rank : 214)
Query Neighborhood Hits	350	Target Neighborhood Hits	307	Shared Neighborhood Hits	261
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASB13_HUMAN
NC score	0.690500 (rank : 127)	θ value	0.279714 (rank : 240)
Query Neighborhood Hits	350	Target Neighborhood Hits	293	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

PP16B_MOUSE
NC score	0.690265 (rank : 128)	θ value	0.0330416 (rank : 215)
Query Neighborhood Hits	350	Target Neighborhood Hits	302	Shared Neighborhood Hits	261
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

CT086_HUMAN
NC score	0.689262 (rank : 129)	θ value	0.00509761 (rank : 192)
Query Neighborhood Hits	350	Target Neighborhood Hits	277	Shared Neighborhood Hits	250
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

AN36A_HUMAN
NC score	0.685992 (rank : 130)	θ value	0.00665767 (rank : 194)
Query Neighborhood Hits	350	Target Neighborhood Hits	271	Shared Neighborhood Hits	248
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ASB6_MOUSE
NC score	0.685328 (rank : 131)	θ value	2.21117e-06 (rank : 106)
Query Neighborhood Hits	350	Target Neighborhood Hits	264	Shared Neighborhood Hits	232
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

POT15_HUMAN
NC score	0.683491 (rank : 132)	θ value	1.53129e-07 (rank : 86)
Query Neighborhood Hits	350	Target Neighborhood Hits	893	Shared Neighborhood Hits	278
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ASB12_HUMAN
NC score	0.683282 (rank : 133)	θ value	0.00102713 (rank : 169)
Query Neighborhood Hits	350	Target Neighborhood Hits	263	Shared Neighborhood Hits	249
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANR21_HUMAN
NC score	0.682081 (rank : 134)	θ value	1.17247e-07 (rank : 80)
Query Neighborhood Hits	350	Target Neighborhood Hits	864	Shared Neighborhood Hits	280
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ASB6_HUMAN
NC score	0.681940 (rank : 135)	θ value	4.45536e-07 (rank : 91)
Query Neighborhood Hits	350	Target Neighborhood Hits	256	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

BARD1_HUMAN
NC score	0.679217 (rank : 136)	θ value	0.0193708 (rank : 203)
Query Neighborhood Hits	350	Target Neighborhood Hits	427	Shared Neighborhood Hits	257
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANKY2_MOUSE
NC score	0.671549 (rank : 137)	θ value	7.1131e-05 (rank : 143)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	239
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

BARD1_MOUSE
NC score	0.670218 (rank : 138)	θ value	0.0193708 (rank : 204)
Query Neighborhood Hits	350	Target Neighborhood Hits	411	Shared Neighborhood Hits	253
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB1_HUMAN
NC score	0.670095 (rank : 139)	θ value	0.00228821 (rank : 181)
Query Neighborhood Hits	350	Target Neighborhood Hits	291	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR10_HUMAN
NC score	0.668951 (rank : 140)	θ value	0.00390308 (rank : 185)
Query Neighborhood Hits	350	Target Neighborhood Hits	289	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

NFKB1_HUMAN
NC score	0.667759 (rank : 141)	θ value	3.77169e-06 (rank : 112)
Query Neighborhood Hits	350	Target Neighborhood Hits	306	Shared Neighborhood Hits	256
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

POT14_HUMAN
NC score	0.667375 (rank : 142)	θ value	4.1701e-05 (rank : 138)
Query Neighborhood Hits	350	Target Neighborhood Hits	403	Shared Neighborhood Hits	258
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANR32_HUMAN
NC score	0.665758 (rank : 143)	θ value	0.0431538 (rank : 216)
Query Neighborhood Hits	350	Target Neighborhood Hits	270	Shared Neighborhood Hits	245
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

CTTB2_HUMAN
NC score	0.664507 (rank : 144)	θ value	8.97725e-08 (rank : 78)
Query Neighborhood Hits	350	Target Neighborhood Hits	1061	Shared Neighborhood Hits	288
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR10_MOUSE
NC score	0.663843 (rank : 145)	θ value	0.0193708 (rank : 202)
Query Neighborhood Hits	350	Target Neighborhood Hits	273	Shared Neighborhood Hits	247
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB4_HUMAN
NC score	0.662945 (rank : 146)	θ value	0.125558 (rank : 227)
Query Neighborhood Hits	350	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_MOUSE
NC score	0.662573 (rank : 147)	θ value	0.0431538 (rank : 217)
Query Neighborhood Hits	350	Target Neighborhood Hits	265	Shared Neighborhood Hits	246
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB1_MOUSE
NC score	0.662570 (rank : 148)	θ value	0.00509761 (rank : 190)
Query Neighborhood Hits	350	Target Neighborhood Hits	292	Shared Neighborhood Hits	251
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

BCOR_MOUSE
NC score	0.658718 (rank : 149)	θ value	1.43324e-05 (rank : 127)
Query Neighborhood Hits	350	Target Neighborhood Hits	521	Shared Neighborhood Hits	257
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

MPP8_HUMAN
NC score	0.658591 (rank : 150)	θ value	2.79066e-09 (rank : 42)
Query Neighborhood Hits	350	Target Neighborhood Hits	948	Shared Neighborhood Hits	258
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR32_MOUSE
NC score	0.658368 (rank : 151)	θ value	0.0736092 (rank : 219)
Query Neighborhood Hits	350	Target Neighborhood Hits	285	Shared Neighborhood Hits	245
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR11_HUMAN
NC score	0.655819 (rank : 152)	θ value	0.000158464 (rank : 152)
Query Neighborhood Hits	350	Target Neighborhood Hits	1289	Shared Neighborhood Hits	285
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

NFKB1_MOUSE
NC score	0.652018 (rank : 153)	θ value	0.00134147 (rank : 172)
Query Neighborhood Hits	350	Target Neighborhood Hits	300	Shared Neighborhood Hits	250
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

BCOR_HUMAN
NC score	0.651675 (rank : 154)	θ value	1.87187e-05 (rank : 129)
Query Neighborhood Hits	350	Target Neighborhood Hits	609	Shared Neighborhood Hits	257
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ZDH17_HUMAN
NC score	0.646338 (rank : 155)	θ value	5.44631e-05 (rank : 142)
Query Neighborhood Hits	350	Target Neighborhood Hits	334	Shared Neighborhood Hits	254
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANS4B_HUMAN
NC score	0.644447 (rank : 156)	θ value	0.00509761 (rank : 189)
Query Neighborhood Hits	350	Target Neighborhood Hits	289	Shared Neighborhood Hits	244
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR41_HUMAN
NC score	0.641643 (rank : 157)	θ value	0.0113563 (rank : 199)
Query Neighborhood Hits	350	Target Neighborhood Hits	332	Shared Neighborhood Hits	230
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ASB11_MOUSE
NC score	0.639911 (rank : 158)	θ value	0.125558 (rank : 226)
Query Neighborhood Hits	350	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ZDH17_MOUSE
NC score	0.638439 (rank : 159)	θ value	0.000121331 (rank : 151)
Query Neighborhood Hits	350	Target Neighborhood Hits	328	Shared Neighborhood Hits	253
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANR12_HUMAN
NC score	0.636862 (rank : 160)	θ value	9.92553e-07 (rank : 99)
Query Neighborhood Hits	350	Target Neighborhood Hits	1081	Shared Neighborhood Hits	283
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ASB5_HUMAN
NC score	0.635389 (rank : 161)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	350	Target Neighborhood Hits	283	Shared Neighborhood Hits	249
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB11_HUMAN
NC score	0.634755 (rank : 162)	θ value	1.38821 (rank : 271)
Query Neighborhood Hits	350	Target Neighborhood Hits	271	Shared Neighborhood Hits	243
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

POT22_HUMAN
NC score	0.633712 (rank : 163)	θ value	5.44631e-05 (rank : 141)
Query Neighborhood Hits	350	Target Neighborhood Hits	266	Shared Neighborhood Hits	244
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

USH1G_HUMAN
NC score	0.632936 (rank : 164)	θ value	1.06291 (rank : 268)
Query Neighborhood Hits	350	Target Neighborhood Hits	267	Shared Neighborhood Hits	243
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
NC score	0.632561 (rank : 165)	θ value	1.06291 (rank : 269)
Query Neighborhood Hits	350	Target Neighborhood Hits	271	Shared Neighborhood Hits	244
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ZDH13_HUMAN
NC score	0.631474 (rank : 166)	θ value	0.00298849 (rank : 183)
Query Neighborhood Hits	350	Target Neighborhood Hits	322	Shared Neighborhood Hits	253
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANS4B_MOUSE
NC score	0.630362 (rank : 167)	θ value	0.00665767 (rank : 195)
Query Neighborhood Hits	350	Target Neighborhood Hits	294	Shared Neighborhood Hits	239
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

NFKB2_HUMAN
NC score	0.627016 (rank : 168)	θ value	0.000786445 (rank : 168)
Query Neighborhood Hits	350	Target Neighborhood Hits	325	Shared Neighborhood Hits	255
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ASB5_MOUSE
NC score	0.625942 (rank : 169)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	350	Target Neighborhood Hits	266	Shared Neighborhood Hits	240
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ZDH13_MOUSE
NC score	0.625516 (rank : 170)	θ value	0.00175202 (rank : 179)
Query Neighborhood Hits	350	Target Neighborhood Hits	329	Shared Neighborhood Hits	256
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ASB9_HUMAN
NC score	0.623297 (rank : 171)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	350	Target Neighborhood Hits	267	Shared Neighborhood Hits	240
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

SHAN1_HUMAN
NC score	0.623016 (rank : 172)	θ value	6.43352e-06 (rank : 117)
Query Neighborhood Hits	350	Target Neighborhood Hits	1041	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR37_MOUSE
NC score	0.621811 (rank : 173)	θ value	0.00390308 (rank : 186)
Query Neighborhood Hits	350	Target Neighborhood Hits	237	Shared Neighborhood Hits	222
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR37_HUMAN
NC score	0.621350 (rank : 174)	θ value	0.279714 (rank : 239)
Query Neighborhood Hits	350	Target Neighborhood Hits	247	Shared Neighborhood Hits	229
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

SNCAP_HUMAN
NC score	0.616508 (rank : 175)	θ value	0.21417 (rank : 237)
Query Neighborhood Hits	350	Target Neighborhood Hits	313	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

CLPB_MOUSE
NC score	0.615755 (rank : 176)	θ value	0.125558 (rank : 228)
Query Neighborhood Hits	350	Target Neighborhood Hits	289	Shared Neighborhood Hits	233
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

NFKB2_MOUSE
NC score	0.609841 (rank : 177)	θ value	0.0193708 (rank : 206)
Query Neighborhood Hits	350	Target Neighborhood Hits	326	Shared Neighborhood Hits	253
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ASB9_MOUSE
NC score	0.609544 (rank : 178)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	350	Target Neighborhood Hits	257	Shared Neighborhood Hits	237
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

RAI14_HUMAN
NC score	0.602948 (rank : 179)	θ value	2.0648e-12 (rank : 10)
Query Neighborhood Hits	350	Target Neighborhood Hits	1367	Shared Neighborhood Hits	290
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

A20A3_HUMAN
NC score	0.594105 (rank : 180)	θ value	0.0252991 (rank : 209)
Query Neighborhood Hits	350	Target Neighborhood Hits	692	Shared Neighborhood Hits	276
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.593343 (rank : 181)	θ value	0.0563607 (rank : 218)
Query Neighborhood Hits	350	Target Neighborhood Hits	716	Shared Neighborhood Hits	276
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.592960 (rank : 182)	θ value	0.0252991 (rank : 208)
Query Neighborhood Hits	350	Target Neighborhood Hits	698	Shared Neighborhood Hits	274
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

OSBL1_HUMAN
NC score	0.590486 (rank : 183)	θ value	2.88788e-06 (rank : 110)
Query Neighborhood Hits	350	Target Neighborhood Hits	368	Shared Neighborhood Hits	258
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

A20A4_HUMAN
NC score	0.590065 (rank : 184)	θ value	0.0252991 (rank : 210)
Query Neighborhood Hits	350	Target Neighborhood Hits	710	Shared Neighborhood Hits	276
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

OSTF1_MOUSE
NC score	0.582028 (rank : 185)	θ value	0.000602161 (rank : 165)
Query Neighborhood Hits	350	Target Neighborhood Hits	467	Shared Neighborhood Hits	237
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANR18_HUMAN
NC score	0.570300 (rank : 186)	θ value	0.000270298 (rank : 157)
Query Neighborhood Hits	350	Target Neighborhood Hits	1106	Shared Neighborhood Hits	273
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

RAI14_MOUSE
NC score	0.568907 (rank : 187)	θ value	4.59992e-12 (rank : 14)
Query Neighborhood Hits	350	Target Neighborhood Hits	1505	Shared Neighborhood Hits	295
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

OSBL1_MOUSE
NC score	0.568384 (rank : 188)	θ value	0.000121331 (rank : 150)
Query Neighborhood Hits	350	Target Neighborhood Hits	336	Shared Neighborhood Hits	253
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR43_HUMAN
NC score	0.566304 (rank : 189)	θ value	0.000270298 (rank : 158)
Query Neighborhood Hits	350	Target Neighborhood Hits	209	Shared Neighborhood Hits	195
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

KRIT1_MOUSE
NC score	0.566146 (rank : 190)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	350	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

OSTF1_HUMAN
NC score	0.565585 (rank : 191)	θ value	0.0193708 (rank : 207)
Query Neighborhood Hits	350	Target Neighborhood Hits	466	Shared Neighborhood Hits	237
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR43_MOUSE
NC score	0.559970 (rank : 192)	θ value	0.00175202 (rank : 174)
Query Neighborhood Hits	350	Target Neighborhood Hits	214	Shared Neighborhood Hits	199
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

KRIT1_HUMAN
NC score	0.558469 (rank : 193)	θ value	0.21417 (rank : 235)
Query Neighborhood Hits	350	Target Neighborhood Hits	258	Shared Neighborhood Hits	215
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

CD2A1_MOUSE
NC score	0.557153 (rank : 194)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	350	Target Neighborhood Hits	206	Shared Neighborhood Hits	188
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

AN30A_HUMAN
NC score	0.555219 (rank : 195)	θ value	1.53129e-07 (rank : 83)
Query Neighborhood Hits	350	Target Neighborhood Hits	1119	Shared Neighborhood Hits	279
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR45_MOUSE
NC score	0.549810 (rank : 196)	θ value	0.00035302 (rank : 160)
Query Neighborhood Hits	350	Target Neighborhood Hits	204	Shared Neighborhood Hits	182
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HECD1_HUMAN
NC score	0.546727 (rank : 197)	θ value	0.00134147 (rank : 171)
Query Neighborhood Hits	350	Target Neighborhood Hits	371	Shared Neighborhood Hits	251
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

CLPB_HUMAN
NC score	0.546650 (rank : 198)	θ value	0.0330416 (rank : 213)
Query Neighborhood Hits	350	Target Neighborhood Hits	265	Shared Neighborhood Hits	219
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

NUD12_MOUSE
NC score	0.544659 (rank : 199)	θ value	0.0113563 (rank : 200)
Query Neighborhood Hits	350	Target Neighborhood Hits	243	Shared Neighborhood Hits	213
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ANKY1_HUMAN
NC score	0.538938 (rank : 200)	θ value	0.000461057 (rank : 162)
Query Neighborhood Hits	350	Target Neighborhood Hits	248	Shared Neighborhood Hits	197
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

NUD12_HUMAN
NC score	0.523448 (rank : 201)	θ value	0.0252991 (rank : 212)
Query Neighborhood Hits	350	Target Neighborhood Hits	222	Shared Neighborhood Hits	195
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CDN2B_MOUSE
NC score	0.516014 (rank : 202)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	350	Target Neighborhood Hits	201	Shared Neighborhood Hits	184
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

ANR45_HUMAN
NC score	0.513034 (rank : 203)	θ value	0.00228821 (rank : 180)
Query Neighborhood Hits	350	Target Neighborhood Hits	201	Shared Neighborhood Hits	177
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASPP2_HUMAN
NC score	0.511924 (rank : 204)	θ value	7.1131e-05 (rank : 146)
Query Neighborhood Hits	350	Target Neighborhood Hits	1156	Shared Neighborhood Hits	279
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ABTB2_MOUSE
NC score	0.504966 (rank : 205)	θ value	0.000602161 (rank : 164)
Query Neighborhood Hits	350	Target Neighborhood Hits	414	Shared Neighborhood Hits	226
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR40_HUMAN
NC score	0.499623 (rank : 206)	θ value	1.81305 (rank : 278)
Query Neighborhood Hits	350	Target Neighborhood Hits	224	Shared Neighborhood Hits	192
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ABTB2_HUMAN
NC score	0.496796 (rank : 207)	θ value	0.813845 (rank : 260)
Query Neighborhood Hits	350	Target Neighborhood Hits	391	Shared Neighborhood Hits	226
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR40_MOUSE
NC score	0.496316 (rank : 208)	θ value	1.81305 (rank : 279)
Query Neighborhood Hits	350	Target Neighborhood Hits	228	Shared Neighborhood Hits	195
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANKK1_HUMAN
NC score	0.495784 (rank : 209)	θ value	3.64472e-09 (rank : 44)
Query Neighborhood Hits	350	Target Neighborhood Hits	1075	Shared Neighborhood Hits	267
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

RIPK4_HUMAN
NC score	0.492768 (rank : 210)	θ value	2.52405e-10 (rank : 25)
Query Neighborhood Hits	350	Target Neighborhood Hits	1094	Shared Neighborhood Hits	267
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

IASPP_HUMAN
NC score	0.490401 (rank : 211)	θ value	0.47712 (rank : 249)
Query Neighborhood Hits	350	Target Neighborhood Hits	688	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TRPV6_MOUSE
NC score	0.489848 (rank : 212)	θ value	0.0961366 (rank : 224)
Query Neighborhood Hits	350	Target Neighborhood Hits	284	Shared Neighborhood Hits	236
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

CENB5_HUMAN
NC score	0.489285 (rank : 213)	θ value	1.69304e-06 (rank : 104)
Query Neighborhood Hits	350	Target Neighborhood Hits	395	Shared Neighborhood Hits	247
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CDN2B_HUMAN
NC score	0.484760 (rank : 214)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	350	Target Neighborhood Hits	196	Shared Neighborhood Hits	179
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CD2A1_HUMAN
NC score	0.484035 (rank : 215)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	350	Target Neighborhood Hits	196	Shared Neighborhood Hits	178
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

UACA_HUMAN
NC score	0.482586 (rank : 216)	θ value	4.30538e-10 (rank : 29)
Query Neighborhood Hits	350	Target Neighborhood Hits	1622	Shared Neighborhood Hits	296
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ASPP1_HUMAN
NC score	0.481538 (rank : 217)	θ value	0.00175202 (rank : 175)
Query Neighborhood Hits	350	Target Neighborhood Hits	956	Shared Neighborhood Hits	270
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ANKK1_MOUSE
NC score	0.480220 (rank : 218)	θ value	2.36244e-08 (rank : 63)
Query Neighborhood Hits	350	Target Neighborhood Hits	1072	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

CENB1_HUMAN
NC score	0.468617 (rank : 219)	θ value	0.00390308 (rank : 188)
Query Neighborhood Hits	350	Target Neighborhood Hits	383	Shared Neighborhood Hits	240
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ASPP1_MOUSE
NC score	0.467040 (rank : 220)	θ value	0.00175202 (rank : 176)
Query Neighborhood Hits	350	Target Neighborhood Hits	1244	Shared Neighborhood Hits	275
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ILK2_HUMAN
NC score	0.461615 (rank : 221)	θ value	9.29e-05 (rank : 149)
Query Neighborhood Hits	350	Target Neighborhood Hits	848	Shared Neighborhood Hits	262
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

UACA_MOUSE
NC score	0.458086 (rank : 222)	θ value	2.13673e-09 (rank : 39)
Query Neighborhood Hits	350	Target Neighborhood Hits	1620	Shared Neighborhood Hits	291
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AN13B_MOUSE
NC score	0.457397 (rank : 223)	θ value	0.125558 (rank : 225)
Query Neighborhood Hits	350	Target Neighborhood Hits	276	Shared Neighborhood Hits	244
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.456571 (rank : 224)	θ value	0.0961366 (rank : 222)
Query Neighborhood Hits	350	Target Neighborhood Hits	265	Shared Neighborhood Hits	242
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CENB2_HUMAN
NC score	0.449279 (rank : 225)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	350	Target Neighborhood Hits	425	Shared Neighborhood Hits	245
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ILK1_HUMAN
NC score	0.445915 (rank : 226)	θ value	9.29e-05 (rank : 148)
Query Neighborhood Hits	350	Target Neighborhood Hits	857	Shared Neighborhood Hits	262
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

IASPP_MOUSE
NC score	0.444223 (rank : 227)	θ value	0.813845 (rank : 263)
Query Neighborhood Hits	350	Target Neighborhood Hits	1024	Shared Neighborhood Hits	256
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ILK_MOUSE
NC score	0.443122 (rank : 228)	θ value	0.00020696 (rank : 156)
Query Neighborhood Hits	350	Target Neighborhood Hits	858	Shared Neighborhood Hits	262
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

TRPV5_MOUSE
NC score	0.442636 (rank : 229)	θ value	0.163984 (rank : 233)
Query Neighborhood Hits	350	Target Neighborhood Hits	278	Shared Neighborhood Hits	229
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

NOTC4_MOUSE
NC score	0.438639 (rank : 230)	θ value	3.08544e-08 (rank : 68)
Query Neighborhood Hits	350	Target Neighborhood Hits	872	Shared Neighborhood Hits	258
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ASB14_HUMAN
NC score	0.434499 (rank : 231)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	350	Target Neighborhood Hits	187	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

DDFL1_MOUSE
NC score	0.433894 (rank : 232)	θ value	4.1701e-05 (rank : 136)
Query Neighborhood Hits	350	Target Neighborhood Hits	324	Shared Neighborhood Hits	240
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

NOTC4_HUMAN
NC score	0.432908 (rank : 233)	θ value	3.08544e-08 (rank : 67)
Query Neighborhood Hits	350	Target Neighborhood Hits	905	Shared Neighborhood Hits	260
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

GLSL_HUMAN
NC score	0.432163 (rank : 234)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	350	Target Neighborhood Hits	211	Shared Neighborhood Hits	192
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ANR26_MOUSE
NC score	0.429258 (rank : 235)	θ value	1.17247e-07 (rank : 81)
Query Neighborhood Hits	350	Target Neighborhood Hits	1554	Shared Neighborhood Hits	288
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GLSL_MOUSE
NC score	0.426301 (rank : 236)	θ value	1.81305 (rank : 282)
Query Neighborhood Hits	350	Target Neighborhood Hits	212	Shared Neighborhood Hits	192
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TRPV5_HUMAN
NC score	0.425880 (rank : 237)	θ value	0.47712 (rank : 253)
Query Neighborhood Hits	350	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

AN13C_HUMAN
NC score	0.422473 (rank : 238)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	350	Target Neighborhood Hits	241	Shared Neighborhood Hits	223
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT2_MOUSE
NC score	0.417851 (rank : 239)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	350	Target Neighborhood Hits	323	Shared Neighborhood Hits	234
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

TRPV6_HUMAN
NC score	0.416011 (rank : 240)	θ value	0.47712 (rank : 254)
Query Neighborhood Hits	350	Target Neighborhood Hits	262	Shared Neighborhood Hits	211
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

AN13C_MOUSE
NC score	0.415494 (rank : 241)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	350	Target Neighborhood Hits	242	Shared Neighborhood Hits	219
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

NOTC3_MOUSE
NC score	0.406417 (rank : 242)	θ value	4.76016e-09 (rank : 48)
Query Neighborhood Hits	350	Target Neighborhood Hits	975	Shared Neighborhood Hits	256
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANR26_HUMAN
NC score	0.405126 (rank : 243)	θ value	0.000786445 (rank : 167)
Query Neighborhood Hits	350	Target Neighborhood Hits	1614	Shared Neighborhood Hits	289
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC3_HUMAN
NC score	0.403994 (rank : 244)	θ value	4.76016e-09 (rank : 47)
Query Neighborhood Hits	350	Target Neighborhood Hits	1062	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.402301 (rank : 245)	θ value	2.52405e-10 (rank : 24)
Query Neighborhood Hits	350	Target Neighborhood Hits	906	Shared Neighborhood Hits	261
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

GIT1_MOUSE
NC score	0.400984 (rank : 246)	θ value	2.36792 (rank : 289)
Query Neighborhood Hits	350	Target Neighborhood Hits	341	Shared Neighborhood Hits	232
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

NOTC2_HUMAN
NC score	0.400942 (rank : 247)	θ value	2.79066e-09 (rank : 43)
Query Neighborhood Hits	350	Target Neighborhood Hits	1113	Shared Neighborhood Hits	257
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

AN13A_HUMAN
NC score	0.400308 (rank : 248)	θ value	0.47712 (rank : 247)
Query Neighborhood Hits	350	Target Neighborhood Hits	243	Shared Neighborhood Hits	212
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

GIT1_HUMAN
NC score	0.399541 (rank : 249)	θ value	2.36792 (rank : 288)
Query Neighborhood Hits	350	Target Neighborhood Hits	336	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

NOTC2_MOUSE
NC score	0.397650 (rank : 250)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	350	Target Neighborhood Hits	1069	Shared Neighborhood Hits	257
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

GLSK_HUMAN
NC score	0.393230 (rank : 251)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	350	Target Neighborhood Hits	204	Shared Neighborhood Hits	182
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

TNI3K_HUMAN
NC score	0.387213 (rank : 252)	θ value	1.29631e-06 (rank : 102)
Query Neighborhood Hits	350	Target Neighborhood Hits	1084	Shared Neighborhood Hits	267
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

GIT2_HUMAN
NC score	0.383994 (rank : 253)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	350	Target Neighborhood Hits	381	Shared Neighborhood Hits	230
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

TNI3K_MOUSE
NC score	0.383663 (rank : 254)	θ value	5.26297e-08 (rank : 76)
Query Neighborhood Hits	350	Target Neighborhood Hits	1079	Shared Neighborhood Hits	267
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CT012_MOUSE
NC score	0.383198 (rank : 255)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	350	Target Neighborhood Hits	229	Shared Neighborhood Hits	164
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

AN13A_MOUSE
NC score	0.380001 (rank : 256)	θ value	0.279714 (rank : 238)
Query Neighborhood Hits	350	Target Neighborhood Hits	226	Shared Neighborhood Hits	207
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

DAPK1_MOUSE
NC score	0.357948 (rank : 257)	θ value	8.11959e-09 (rank : 53)
Query Neighborhood Hits	350	Target Neighborhood Hits	1138	Shared Neighborhood Hits	266
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

NOTC1_MOUSE
NC score	0.353455 (rank : 258)	θ value	1.80886e-08 (rank : 62)
Query Neighborhood Hits	350	Target Neighborhood Hits	916	Shared Neighborhood Hits	243
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DAPK1_HUMAN
NC score	0.350364 (rank : 259)	θ value	2.13673e-09 (rank : 38)
Query Neighborhood Hits	350	Target Neighborhood Hits	1130	Shared Neighborhood Hits	267
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TEX14_MOUSE
NC score	0.347609 (rank : 260)	θ value	0.00175202 (rank : 178)
Query Neighborhood Hits	350	Target Neighborhood Hits	1333	Shared Neighborhood Hits	260
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_HUMAN
NC score	0.340611 (rank : 261)	θ value	0.125558 (rank : 230)
Query Neighborhood Hits	350	Target Neighborhood Hits	1103	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CT012_HUMAN
NC score	0.335545 (rank : 262)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	350	Target Neighborhood Hits	205	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DGKZ_HUMAN
NC score	0.320548 (rank : 263)	θ value	0.62314 (rank : 255)
Query Neighborhood Hits	350	Target Neighborhood Hits	551	Shared Neighborhood Hits	207
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG2_MOUSE
NC score	0.320086 (rank : 264)	θ value	0.0148317 (rank : 201)
Query Neighborhood Hits	350	Target Neighborhood Hits	463	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG2_HUMAN
NC score	0.320033 (rank : 265)	θ value	0.00509761 (rank : 191)
Query Neighborhood Hits	350	Target Neighborhood Hits	471	Shared Neighborhood Hits	242
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

DDFL1_HUMAN
NC score	0.319796 (rank : 266)	θ value	1.38821 (rank : 273)
Query Neighborhood Hits	350	Target Neighborhood Hits	353	Shared Neighborhood Hits	220
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

BAT4_MOUSE
NC score	0.318342 (rank : 267)	θ value	0.00390308 (rank : 187)
Query Neighborhood Hits	350	Target Neighborhood Hits	171	Shared Neighborhood Hits	114
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

DDEF2_HUMAN
NC score	0.315505 (rank : 268)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	350	Target Neighborhood Hits	599	Shared Neighborhood Hits	229
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.315040 (rank : 269)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	350	Target Neighborhood Hits	625	Shared Neighborhood Hits	232
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CENG1_HUMAN
NC score	0.301638 (rank : 270)	θ value	0.365318 (rank : 245)
Query Neighborhood Hits	350	Target Neighborhood Hits	544	Shared Neighborhood Hits	230
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
NC score	0.300115 (rank : 271)	θ value	0.813845 (rank : 262)
Query Neighborhood Hits	350	Target Neighborhood Hits	531	Shared Neighborhood Hits	226
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

DGKZ_MOUSE
NC score	0.290858 (rank : 272)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	350	Target Neighborhood Hits	542	Shared Neighborhood Hits	193
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKI_HUMAN
NC score	0.278699 (rank : 273)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	350	Target Neighborhood Hits	609	Shared Neighborhood Hits	205
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

BAT4_HUMAN
NC score	0.276779 (rank : 274)	θ value	0.0193708 (rank : 205)
Query Neighborhood Hits	350	Target Neighborhood Hits	157	Shared Neighborhood Hits	104
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CENG3_HUMAN
NC score	0.270451 (rank : 275)	θ value	2.36792 (rank : 285)
Query Neighborhood Hits	350	Target Neighborhood Hits	455	Shared Neighborhood Hits	216
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
NC score	0.270029 (rank : 276)	θ value	2.36792 (rank : 286)
Query Neighborhood Hits	350	Target Neighborhood Hits	467	Shared Neighborhood Hits	215
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ANKZ1_MOUSE
NC score	0.268492 (rank : 277)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	350	Target Neighborhood Hits	208	Shared Neighborhood Hits	143
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

IKBL_HUMAN
NC score	0.264892 (rank : 278)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	350	Target Neighborhood Hits	168	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ANKZ1_HUMAN
NC score	0.259570 (rank : 279)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	350	Target Neighborhood Hits	236	Shared Neighborhood Hits	148
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

IKBL_MOUSE
NC score	0.258197 (rank : 280)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	350	Target Neighborhood Hits	196	Shared Neighborhood Hits	136
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ABTB1_MOUSE
NC score	0.248839 (rank : 281)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	350	Target Neighborhood Hits	349	Shared Neighborhood Hits	168
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

DDEF1_MOUSE
NC score	0.246104 (rank : 282)	θ value	0.47712 (rank : 248)
Query Neighborhood Hits	350	Target Neighborhood Hits	592	Shared Neighborhood Hits	189
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

TRPV3_HUMAN
NC score	0.237096 (rank : 283)	θ value	0.00665767 (rank : 196)
Query Neighborhood Hits	350	Target Neighborhood Hits	198	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.236916 (rank : 284)	θ value	0.00509761 (rank : 193)
Query Neighborhood Hits	350	Target Neighborhood Hits	188	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

CLR59_HUMAN
NC score	0.236564 (rank : 285)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	350	Target Neighborhood Hits	163	Shared Neighborhood Hits	135
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

ANKR9_MOUSE
NC score	0.222763 (rank : 286)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	350	Target Neighborhood Hits	120	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ABTB1_HUMAN
NC score	0.211291 (rank : 287)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	350	Target Neighborhood Hits	325	Shared Neighborhood Hits	154
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

TRPV1_MOUSE
NC score	0.201142 (rank : 288)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	350	Target Neighborhood Hits	189	Shared Neighborhood Hits	145
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
NC score	0.188485 (rank : 289)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	350	Target Neighborhood Hits	184	Shared Neighborhood Hits	138
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

ANKR9_HUMAN
NC score	0.182912 (rank : 290)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	350	Target Neighborhood Hits	99	Shared Neighborhood Hits	91
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

RSNL2_HUMAN
NC score	0.182177 (rank : 291)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	350	Target Neighborhood Hits	136	Shared Neighborhood Hits	110
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV2_HUMAN
NC score	0.169945 (rank : 292)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	350	Target Neighborhood Hits	130	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CMTA1_HUMAN
NC score	0.161586 (rank : 293)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	350	Target Neighborhood Hits	217	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

RSNL2_MOUSE
NC score	0.153061 (rank : 294)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	350	Target Neighborhood Hits	129	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV2_MOUSE
NC score	0.131461 (rank : 295)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	350	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CMTA2_HUMAN
NC score	0.122399 (rank : 296)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	350	Target Neighborhood Hits	199	Shared Neighborhood Hits	82
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ANKF1_HUMAN
NC score	0.118563 (rank : 297)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	350	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CMTA2_MOUSE
NC score	0.112322 (rank : 298)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	350	Target Neighborhood Hits	216	Shared Neighborhood Hits	74
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPV4_HUMAN
NC score	0.106759 (rank : 299)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	350	Target Neighborhood Hits	150	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
NC score	0.096912 (rank : 300)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	350	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPC6_HUMAN
NC score	0.083434 (rank : 301)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	350	Target Neighborhood Hits	171	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

LRRK1_MOUSE
NC score	0.075068 (rank : 302)	θ value	0.62314 (rank : 257)
Query Neighborhood Hits	350	Target Neighborhood Hits	1267	Shared Neighborhood Hits	120
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

CU081_HUMAN
NC score	0.066227 (rank : 303)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	350	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

TRPC3_HUMAN
NC score	0.063774 (rank : 304)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	350	Target Neighborhood Hits	137	Shared Neighborhood Hits	73
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
NC score	0.059727 (rank : 305)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	350	Target Neighborhood Hits	171	Shared Neighborhood Hits	82
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

JAG2_MOUSE
NC score	0.058972 (rank : 306)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	350	Target Neighborhood Hits	504	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LCE1B_HUMAN
NC score	0.058624 (rank : 307)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	350	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

JAG1_HUMAN
NC score	0.057932 (rank : 308)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	350	Target Neighborhood Hits	514	Shared Neighborhood Hits	8
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG2_HUMAN
NC score	0.057914 (rank : 309)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	350	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG1_MOUSE
NC score	0.057571 (rank : 310)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	350	Target Neighborhood Hits	518	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DNER_MOUSE
NC score	0.057566 (rank : 311)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	350	Target Neighborhood Hits	413	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

TRPC3_MOUSE
NC score	0.056986 (rank : 312)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	350	Target Neighborhood Hits	131	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

DNER_HUMAN
NC score	0.056704 (rank : 313)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	350	Target Neighborhood Hits	460	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CRUM2_HUMAN
NC score	0.056214 (rank : 314)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	350	Target Neighborhood Hits	453	Shared Neighborhood Hits	8
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

NRBF2_MOUSE
NC score	0.055762 (rank : 315)	θ value	0.62314 (rank : 258)
Query Neighborhood Hits	350	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCQ3, Q9DCG3	Gene names	Nrbf2
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2).

CRUM1_HUMAN
NC score	0.055431 (rank : 316)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	350	Target Neighborhood Hits	457	Shared Neighborhood Hits	8
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

LCE1C_HUMAN
NC score	0.055344 (rank : 317)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	350	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

CRUM1_MOUSE
NC score	0.055184 (rank : 318)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	350	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

LCE1D_HUMAN
NC score	0.054898 (rank : 319)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	350	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

EGFL9_HUMAN
NC score	0.054081 (rank : 320)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	350	Target Neighborhood Hits	365	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
NC score	0.053846 (rank : 321)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	350	Target Neighborhood Hits	379	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

MMRN1_HUMAN
NC score	0.053565 (rank : 322)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	350	Target Neighborhood Hits	636	Shared Neighborhood Hits	38
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

DLL3_MOUSE
NC score	0.052150 (rank : 323)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	350	Target Neighborhood Hits	399	Shared Neighborhood Hits	8
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FBN3_HUMAN
NC score	0.051467 (rank : 324)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	350	Target Neighborhood Hits	543	Shared Neighborhood Hits	8
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

DLL4_MOUSE
NC score	0.051287 (rank : 325)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	350	Target Neighborhood Hits	440	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KR104_HUMAN
NC score	0.051175 (rank : 326)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	350	Target Neighborhood Hits	313	Shared Neighborhood Hits	9
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

FBN2_HUMAN
NC score	0.050989 (rank : 327)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	350	Target Neighborhood Hits	560	Shared Neighborhood Hits	8
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

DLL3_HUMAN
NC score	0.050987 (rank : 328)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	350	Target Neighborhood Hits	419	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FBN2_MOUSE
NC score	0.050833 (rank : 329)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	350	Target Neighborhood Hits	549	Shared Neighborhood Hits	8
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.050826 (rank : 330)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	350	Target Neighborhood Hits	563	Shared Neighborhood Hits	9
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
NC score	0.050708 (rank : 331)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	350	Target Neighborhood Hits	557	Shared Neighborhood Hits	10
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

KTN1_HUMAN
NC score	0.050700 (rank : 332)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	350	Target Neighborhood Hits	1197	Shared Neighborhood Hits	57
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TRPC5_MOUSE
NC score	0.050589 (rank : 333)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	350	Target Neighborhood Hits	124	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

CCD41_MOUSE
NC score	0.050460 (rank : 334)	θ value	0.365318 (rank : 244)
Query Neighborhood Hits	350	Target Neighborhood Hits	1399	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DLL4_HUMAN
NC score	0.050281 (rank : 335)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	350	Target Neighborhood Hits	435	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LRRK1_HUMAN
NC score	0.050249 (rank : 336)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	350	Target Neighborhood Hits	1237	Shared Neighborhood Hits	97
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

DLK_MOUSE
NC score	0.050190 (rank : 337)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	350	Target Neighborhood Hits	374	Shared Neighborhood Hits	8
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

AKAP9_HUMAN
NC score	0.049655 (rank : 338)	θ value	1.81305 (rank : 277)
Query Neighborhood Hits	350	Target Neighborhood Hits	1710	Shared Neighborhood Hits	70
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

RB6I2_HUMAN
NC score	0.049392 (rank : 339)	θ value	0.813845 (rank : 265)
Query Neighborhood Hits	350	Target Neighborhood Hits	1584	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

NRBF2_HUMAN
NC score	0.049000 (rank : 340)	θ value	0.0961366 (rank : 223)
Query Neighborhood Hits	350	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

KTN1_MOUSE
NC score	0.046516 (rank : 341)	θ value	3.0926 (rank : 294)
Query Neighborhood Hits	350	Target Neighborhood Hits	1324	Shared Neighborhood Hits	64
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

GOGA3_MOUSE
NC score	0.045719 (rank : 342)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	350	Target Neighborhood Hits	1437	Shared Neighborhood Hits	64
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CP250_MOUSE
NC score	0.045173 (rank : 343)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	350	Target Neighborhood Hits	1583	Shared Neighborhood Hits	70
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

GCC1_MOUSE
NC score	0.044469 (rank : 344)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	350	Target Neighborhood Hits	777	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

RP1L1_HUMAN
NC score	0.043690 (rank : 345)	θ value	0.47712 (rank : 252)
Query Neighborhood Hits	350	Target Neighborhood Hits	1072	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

PHLB1_HUMAN
NC score	0.042818 (rank : 346)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	350	Target Neighborhood Hits	1038	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

NFM_HUMAN
NC score	0.041499 (rank : 347)	θ value	0.279714 (rank : 241)
Query Neighborhood Hits	350	Target Neighborhood Hits	1328	Shared Neighborhood Hits	73
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SYNE2_HUMAN
NC score	0.040165 (rank : 348)	θ value	0.125558 (rank : 229)
Query Neighborhood Hits	350	Target Neighborhood Hits	1323	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

HIP1_HUMAN
NC score	0.039523 (rank : 349)	θ value	0.62314 (rank : 256)
Query Neighborhood Hits	350	Target Neighborhood Hits	1016	Shared Neighborhood Hits	53
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

ALEX_HUMAN
NC score	0.038540 (rank : 350)	θ value	0.365318 (rank : 242)
Query Neighborhood Hits	350	Target Neighborhood Hits	361	Shared Neighborhood Hits	15
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CENPE_HUMAN
NC score	0.037709 (rank : 351)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	350	Target Neighborhood Hits	2060	Shared Neighborhood Hits	75
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GFAP_HUMAN
NC score	0.037493 (rank : 352)	θ value	0.00228821 (rank : 182)
Query Neighborhood Hits	350	Target Neighborhood Hits	723	Shared Neighborhood Hits	43
SwissProt Accessions	P14136, Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4, Q96P18, Q9UFD0	Gene names	GFAP
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

NASP_HUMAN
NC score	0.037465 (rank : 353)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	350	Target Neighborhood Hits	709	Shared Neighborhood Hits	37
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

GFAP_MOUSE
NC score	0.037400 (rank : 354)	θ value	0.000461057 (rank : 163)
Query Neighborhood Hits	350	Target Neighborhood Hits	725	Shared Neighborhood Hits	43
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

RIMB1_MOUSE
NC score	0.036293 (rank : 355)	θ value	0.365318 (rank : 246)
Query Neighborhood Hits	350	Target Neighborhood Hits	1376	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NIPBL_HUMAN
NC score	0.035637 (rank : 356)	θ value	0.21417 (rank : 236)
Query Neighborhood Hits	350	Target Neighborhood Hits	1311	Shared Neighborhood Hits	54
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

K1543_MOUSE
NC score	0.035313 (rank : 357)	θ value	1.06291 (rank : 266)
Query Neighborhood Hits	350	Target Neighborhood Hits	497	Shared Neighborhood Hits	26
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

CCD62_HUMAN
NC score	0.035113 (rank : 358)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	350	Target Neighborhood Hits	631	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

LMNB2_MOUSE
NC score	0.034255 (rank : 359)	θ value	1.06291 (rank : 267)
Query Neighborhood Hits	350	Target Neighborhood Hits	674	Shared Neighborhood Hits	41
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

LMNB2_HUMAN
NC score	0.034002 (rank : 360)	θ value	1.38821 (rank : 276)
Query Neighborhood Hits	350	Target Neighborhood Hits	723	Shared Neighborhood Hits	45
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

MAP1B_HUMAN
NC score	0.031337 (rank : 361)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	350	Target Neighborhood Hits	903	Shared Neighborhood Hits	45
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CCD12_MOUSE
NC score	0.030980 (rank : 362)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	350	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R344, Q9CZH5	Gene names	Ccdc12
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 12.

PHLB1_MOUSE
NC score	0.029136 (rank : 363)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	350	Target Neighborhood Hits	678	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

HOME3_MOUSE
NC score	0.028743 (rank : 364)	θ value	1.38821 (rank : 275)
Query Neighborhood Hits	350	Target Neighborhood Hits	316	Shared Neighborhood Hits	28
SwissProt Accessions	Q99JP6, Q9Z215	Gene names	Homer3
Domain Architecture
Description	Homer protein homolog 3 (Homer-3).

CTRO_MOUSE
NC score	0.026880 (rank : 365)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	350	Target Neighborhood Hits	2344	Shared Neighborhood Hits	82
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ARI1A_HUMAN
NC score	0.025390 (rank : 366)	θ value	1.81305 (rank : 280)
Query Neighborhood Hits	350	Target Neighborhood Hits	787	Shared Neighborhood Hits	35
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

TLN1_MOUSE
NC score	0.025116 (rank : 367)	θ value	1.81305 (rank : 284)
Query Neighborhood Hits	350	Target Neighborhood Hits	213	Shared Neighborhood Hits	14
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

K1H4_HUMAN
NC score	0.025078 (rank : 368)	θ value	0.47712 (rank : 250)
Query Neighborhood Hits	350	Target Neighborhood Hits	476	Shared Neighborhood Hits	37
SwissProt Accessions	O76011	Gene names	KRTHA4, HHA4, HKA4
Domain Architecture
Description	Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4).

CTRO_HUMAN
NC score	0.023854 (rank : 369)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	350	Target Neighborhood Hits	2092	Shared Neighborhood Hits	71
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

LSD1_MOUSE
NC score	0.022907 (rank : 370)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	350	Target Neighborhood Hits	224	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

P210L_HUMAN
NC score	0.022830 (rank : 371)	θ value	0.62314 (rank : 259)
Query Neighborhood Hits	350	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VU65, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6	Gene names	NUP210L
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

LEO1_HUMAN
NC score	0.021905 (rank : 372)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	350	Target Neighborhood Hits	958	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LSD1_HUMAN
NC score	0.021499 (rank : 373)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	350	Target Neighborhood Hits	455	Shared Neighborhood Hits	29
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MN1_HUMAN
NC score	0.021119 (rank : 374)	θ value	3.0926 (rank : 296)
Query Neighborhood Hits	350	Target Neighborhood Hits	196	Shared Neighborhood Hits	12
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

P210L_MOUSE
NC score	0.021107 (rank : 375)	θ value	0.813845 (rank : 264)
Query Neighborhood Hits	350	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2F7	Gene names	Nup210l
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

KI21A_MOUSE
NC score	0.020195 (rank : 376)	θ value	3.0926 (rank : 293)
Query Neighborhood Hits	350	Target Neighborhood Hits	1317	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

SPTN5_HUMAN
NC score	0.020126 (rank : 377)	θ value	2.36792 (rank : 291)
Query Neighborhood Hits	350	Target Neighborhood Hits	674	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

CABIN_HUMAN
NC score	0.018507 (rank : 378)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	350	Target Neighborhood Hits	490	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

GON4L_HUMAN
NC score	0.017247 (rank : 379)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	350	Target Neighborhood Hits	555	Shared Neighborhood Hits	28
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IRS2_HUMAN
NC score	0.016663 (rank : 380)	θ value	3.0926 (rank : 292)
Query Neighborhood Hits	350	Target Neighborhood Hits	262	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

RAPSN_HUMAN
NC score	0.016618 (rank : 381)	θ value	4.03905 (rank : 308)
Query Neighborhood Hits	350	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

TLN1_HUMAN
NC score	0.016052 (rank : 382)	θ value	1.81305 (rank : 283)
Query Neighborhood Hits	350	Target Neighborhood Hits	218	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

RAPSN_MOUSE
NC score	0.015662 (rank : 383)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	350	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

CF055_MOUSE
NC score	0.015139 (rank : 384)	θ value	2.36792 (rank : 287)
Query Neighborhood Hits	350	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

CEL_HUMAN
NC score	0.014078 (rank : 385)	θ value	1.38821 (rank : 272)
Query Neighborhood Hits	350	Target Neighborhood Hits	896	Shared Neighborhood Hits	29
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

UBXD6_MOUSE
NC score	0.013907 (rank : 386)	θ value	4.03905 (rank : 309)
Query Neighborhood Hits	350	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ49	Gene names	Ubxd6, D0H8S2298E, Rep8
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 6 (Reproduction 8 protein) (Protein Rep- 8).

MYOC_HUMAN
NC score	0.013895 (rank : 387)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	350	Target Neighborhood Hits	489	Shared Neighborhood Hits	35
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

TM16H_HUMAN
NC score	0.012607 (rank : 388)	θ value	3.0926 (rank : 298)
Query Neighborhood Hits	350	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

SEPT9_HUMAN
NC score	0.011675 (rank : 389)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	350	Target Neighborhood Hits	706	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

RAI1_HUMAN
NC score	0.010872 (rank : 390)	θ value	4.03905 (rank : 307)
Query Neighborhood Hits	350	Target Neighborhood Hits	360	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

GSCR2_HUMAN
NC score	0.010762 (rank : 391)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	350	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZM5, Q9BTC6, Q9HAX6, Q9NPP1, Q9NPR4, Q9UFI2	Gene names	GLTSCR2
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 2 protein (p60).

CECR6_MOUSE
NC score	0.010657 (rank : 392)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	350	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

ABL2_HUMAN
NC score	0.010466 (rank : 393)	θ value	1.38821 (rank : 270)
Query Neighborhood Hits	350	Target Neighborhood Hits	1045	Shared Neighborhood Hits	24
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

MEIS2_MOUSE
NC score	0.010309 (rank : 394)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	350	Target Neighborhood Hits	208	Shared Neighborhood Hits	8
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

EMSY_HUMAN
NC score	0.010293 (rank : 395)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	350	Target Neighborhood Hits	296	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

ADNP_MOUSE
NC score	0.010161 (rank : 396)	θ value	8.99809 (rank : 337)
Query Neighborhood Hits	350	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z103	Gene names	Adnp
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

MATK_HUMAN
NC score	0.009955 (rank : 397)	θ value	3.0926 (rank : 295)
Query Neighborhood Hits	350	Target Neighborhood Hits	954	Shared Neighborhood Hits	21
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MEIS2_HUMAN
NC score	0.009071 (rank : 398)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	350	Target Neighborhood Hits	182	Shared Neighborhood Hits	6
SwissProt Accessions	O14770, Q96KI4, Q96KI5, Q9NRS1, Q9NRS2, Q9NRS3	Gene names	MEIS2, MRG1
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

B3A2_HUMAN
NC score	0.007809 (rank : 399)	θ value	0.813845 (rank : 261)
Query Neighborhood Hits	350	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

KIF17_MOUSE
NC score	0.007314 (rank : 400)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	350	Target Neighborhood Hits	452	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

PDE4C_MOUSE
NC score	0.007213 (rank : 401)	θ value	0.47712 (rank : 251)
Query Neighborhood Hits	350	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

CAC1A_HUMAN
NC score	0.006980 (rank : 402)	θ value	0.365318 (rank : 243)
Query Neighborhood Hits	350	Target Neighborhood Hits	387	Shared Neighborhood Hits	13
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

JARD2_MOUSE
NC score	0.006302 (rank : 403)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	350	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

DC1L2_MOUSE
NC score	0.006114 (rank : 404)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	350	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

B4GN3_HUMAN
NC score	0.005899 (rank : 405)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	350	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

NCOA2_MOUSE
NC score	0.005587 (rank : 406)	θ value	3.0926 (rank : 297)
Query Neighborhood Hits	350	Target Neighborhood Hits	281	Shared Neighborhood Hits	10
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

MAGD4_HUMAN
NC score	0.005376 (rank : 407)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	350	Target Neighborhood Hits	338	Shared Neighborhood Hits	13
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MYCB2_HUMAN
NC score	0.005050 (rank : 408)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	350	Target Neighborhood Hits	390	Shared Neighborhood Hits	14
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ZSWM5_MOUSE
NC score	0.004858 (rank : 409)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	350	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TC6	Gene names	Zswim5, Kiaa1511
Domain Architecture	No domain graphic available
Description	Zinc finger SWIM domain-containing protein 5.

BIG2_HUMAN
NC score	0.004705 (rank : 410)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	350	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

PHC2_MOUSE
NC score	0.004694 (rank : 411)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	350	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

TULP2_HUMAN
NC score	0.004607 (rank : 412)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	350	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	O00295	Gene names	TULP2
Domain Architecture
Description	Tubby-related protein 2 (Tubby-like protein 2).

ARVC_HUMAN
NC score	0.004579 (rank : 413)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	350	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

FOXE2_HUMAN
NC score	0.004068 (rank : 414)	θ value	1.81305 (rank : 281)
Query Neighborhood Hits	350	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

DCAK3_HUMAN
NC score	0.003472 (rank : 415)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	350	Target Neighborhood Hits	888	Shared Neighborhood Hits	21
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

CHD6_HUMAN
NC score	0.003343 (rank : 416)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	350	Target Neighborhood Hits	342	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

KCNQ1_MOUSE
NC score	0.003211 (rank : 417)	θ value	2.36792 (rank : 290)
Query Neighborhood Hits	350	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

PDE9A_HUMAN
NC score	0.002642 (rank : 418)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	350	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

BNC2_HUMAN
NC score	0.002552 (rank : 419)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	350	Target Neighborhood Hits	439	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

PZP_HUMAN
NC score	0.002152 (rank : 420)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	350	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

DDX18_MOUSE
NC score	0.001464 (rank : 421)	θ value	1.38821 (rank : 274)
Query Neighborhood Hits	350	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

ZN445_HUMAN
NC score	-0.011456 (rank : 422)	θ value	4.03905 (rank : 310)
Query Neighborhood Hits	350	Target Neighborhood Hits	764	Shared Neighborhood Hits	5
SwissProt Accessions	P59923	Gene names	ZNF445, ZNF168
Domain Architecture
Description	Zinc finger protein 445.

GLI3_MOUSE
NC score	-0.011754 (rank : 423)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	350	Target Neighborhood Hits	807	Shared Neighborhood Hits	5
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.