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Network neighborhood for query Sequence : ANFY1_MOUSE

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ANFY1_MOUSE
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ANFY1_HUMAN
θ value	0 (rank : 1)	NC score	0.996923 (rank : 2)
Query Neighborhood Hits	480	Target Neighborhood Hits	480	Shared Neighborhood Hits	462
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	480	Target Neighborhood Hits	480	Shared Neighborhood Hits	480
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANK3_HUMAN
θ value	4.69435e-57 (rank : 3)	NC score	0.839797 (rank : 11)
Query Neighborhood Hits	480	Target Neighborhood Hits	853	Shared Neighborhood Hits	311
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANK2_HUMAN
θ value	4.39379e-55 (rank : 4)	NC score	0.786490 (rank : 53)
Query Neighborhood Hits	480	Target Neighborhood Hits	1615	Shared Neighborhood Hits	316
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANK1_HUMAN
θ value	6.14528e-49 (rank : 5)	NC score	0.847867 (rank : 8)
Query Neighborhood Hits	480	Target Neighborhood Hits	416	Shared Neighborhood Hits	305
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	1.36902e-48 (rank : 6)	NC score	0.846966 (rank : 10)
Query Neighborhood Hits	480	Target Neighborhood Hits	430	Shared Neighborhood Hits	305
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR28_MOUSE
θ value	2.76489e-41 (rank : 7)	NC score	0.850711 (rank : 5)
Query Neighborhood Hits	480	Target Neighborhood Hits	314	Shared Neighborhood Hits	300
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_MOUSE
θ value	1.05066e-40 (rank : 8)	NC score	0.848554 (rank : 7)
Query Neighborhood Hits	480	Target Neighborhood Hits	318	Shared Neighborhood Hits	302
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
θ value	2.58786e-39 (rank : 9)	NC score	0.847826 (rank : 9)
Query Neighborhood Hits	480	Target Neighborhood Hits	322	Shared Neighborhood Hits	302
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR28_HUMAN
θ value	5.76516e-39 (rank : 10)	NC score	0.849787 (rank : 6)
Query Neighborhood Hits	480	Target Neighborhood Hits	314	Shared Neighborhood Hits	300
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR44_HUMAN
θ value	6.37413e-38 (rank : 11)	NC score	0.852057 (rank : 4)
Query Neighborhood Hits	480	Target Neighborhood Hits	318	Shared Neighborhood Hits	302
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR50_HUMAN
θ value	4.13158e-37 (rank : 12)	NC score	0.852118 (rank : 3)
Query Neighborhood Hits	480	Target Neighborhood Hits	361	Shared Neighborhood Hits	299
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TNKS1_HUMAN
θ value	1.98606e-31 (rank : 13)	NC score	0.832887 (rank : 12)
Query Neighborhood Hits	480	Target Neighborhood Hits	477	Shared Neighborhood Hits	303
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
θ value	6.38894e-30 (rank : 14)	NC score	0.831919 (rank : 15)
Query Neighborhood Hits	480	Target Neighborhood Hits	361	Shared Neighborhood Hits	304
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANKK1_MOUSE
θ value	7.06379e-29 (rank : 15)	NC score	0.524581 (rank : 209)
Query Neighborhood Hits	480	Target Neighborhood Hits	1072	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANKK1_HUMAN
θ value	2.68423e-28 (rank : 16)	NC score	0.537091 (rank : 205)
Query Neighborhood Hits	480	Target Neighborhood Hits	1075	Shared Neighborhood Hits	300
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

TRPA1_MOUSE
θ value	4.28545e-26 (rank : 17)	NC score	0.828516 (rank : 18)
Query Neighborhood Hits	480	Target Neighborhood Hits	343	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

INVS_HUMAN
θ value	1.62847e-25 (rank : 18)	NC score	0.829984 (rank : 17)
Query Neighborhood Hits	480	Target Neighborhood Hits	455	Shared Neighborhood Hits	289
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	2.77775e-25 (rank : 19)	NC score	0.821512 (rank : 22)
Query Neighborhood Hits	480	Target Neighborhood Hits	609	Shared Neighborhood Hits	289
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

TRPA1_HUMAN
θ value	1.05554e-24 (rank : 20)	NC score	0.828206 (rank : 19)
Query Neighborhood Hits	480	Target Neighborhood Hits	339	Shared Neighborhood Hits	300
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

RIPK4_HUMAN
θ value	9.87957e-23 (rank : 21)	NC score	0.525665 (rank : 208)
Query Neighborhood Hits	480	Target Neighborhood Hits	1094	Shared Neighborhood Hits	304
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

DAPK1_MOUSE
θ value	3.75424e-22 (rank : 22)	NC score	0.375426 (rank : 260)
Query Neighborhood Hits	480	Target Neighborhood Hits	1138	Shared Neighborhood Hits	297
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_HUMAN
θ value	7.82807e-20 (rank : 23)	NC score	0.367377 (rank : 261)
Query Neighborhood Hits	480	Target Neighborhood Hits	1130	Shared Neighborhood Hits	292
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ANKR6_HUMAN
θ value	2.27762e-19 (rank : 24)	NC score	0.832321 (rank : 14)
Query Neighborhood Hits	480	Target Neighborhood Hits	439	Shared Neighborhood Hits	294
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

MIB1_HUMAN
θ value	1.47631e-18 (rank : 25)	NC score	0.787275 (rank : 50)
Query Neighborhood Hits	480	Target Neighborhood Hits	470	Shared Neighborhood Hits	303
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	1.47631e-18 (rank : 26)	NC score	0.786965 (rank : 52)
Query Neighborhood Hits	480	Target Neighborhood Hits	471	Shared Neighborhood Hits	303
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RAI14_MOUSE
θ value	2.5182e-18 (rank : 27)	NC score	0.587883 (rank : 192)
Query Neighborhood Hits	480	Target Neighborhood Hits	1505	Shared Neighborhood Hits	311
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR35_HUMAN
θ value	7.32683e-18 (rank : 28)	NC score	0.763262 (rank : 89)
Query Neighborhood Hits	480	Target Neighborhood Hits	784	Shared Neighborhood Hits	308
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

RAI14_HUMAN
θ value	9.56915e-18 (rank : 29)	NC score	0.619395 (rank : 190)
Query Neighborhood Hits	480	Target Neighborhood Hits	1367	Shared Neighborhood Hits	317
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ASB15_HUMAN
θ value	3.63628e-17 (rank : 30)	NC score	0.791959 (rank : 43)
Query Neighborhood Hits	480	Target Neighborhood Hits	305	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

NOTC3_MOUSE
θ value	6.20254e-17 (rank : 31)	NC score	0.410356 (rank : 250)
Query Neighborhood Hits	480	Target Neighborhood Hits	975	Shared Neighborhood Hits	292
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
θ value	8.10077e-17 (rank : 32)	NC score	0.407885 (rank : 253)
Query Neighborhood Hits	480	Target Neighborhood Hits	1062	Shared Neighborhood Hits	290
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

AN30A_HUMAN
θ value	4.02038e-16 (rank : 33)	NC score	0.584194 (rank : 194)
Query Neighborhood Hits	480	Target Neighborhood Hits	1119	Shared Neighborhood Hits	282
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ASB2_MOUSE
θ value	4.02038e-16 (rank : 34)	NC score	0.807166 (rank : 34)
Query Neighborhood Hits	480	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB2_HUMAN
θ value	5.25075e-16 (rank : 35)	NC score	0.812041 (rank : 28)
Query Neighborhood Hits	480	Target Neighborhood Hits	309	Shared Neighborhood Hits	290
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_MOUSE
θ value	5.25075e-16 (rank : 36)	NC score	0.816512 (rank : 24)
Query Neighborhood Hits	480	Target Neighborhood Hits	316	Shared Neighborhood Hits	292
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR29_HUMAN
θ value	8.95645e-16 (rank : 37)	NC score	0.830276 (rank : 16)
Query Neighborhood Hits	480	Target Neighborhood Hits	294	Shared Neighborhood Hits	290
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

TNI3K_MOUSE
θ value	8.95645e-16 (rank : 38)	NC score	0.406721 (rank : 254)
Query Neighborhood Hits	480	Target Neighborhood Hits	1079	Shared Neighborhood Hits	298
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

PA2G6_MOUSE
θ value	1.16975e-15 (rank : 39)	NC score	0.809272 (rank : 30)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	290
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB3_HUMAN
θ value	1.99529e-15 (rank : 40)	NC score	0.820175 (rank : 23)
Query Neighborhood Hits	480	Target Neighborhood Hits	316	Shared Neighborhood Hits	295
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

FANK1_HUMAN
θ value	2.60593e-15 (rank : 41)	NC score	0.815925 (rank : 25)
Query Neighborhood Hits	480	Target Neighborhood Hits	326	Shared Neighborhood Hits	289
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
θ value	2.60593e-15 (rank : 42)	NC score	0.814321 (rank : 26)
Query Neighborhood Hits	480	Target Neighborhood Hits	325	Shared Neighborhood Hits	284
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

NOTC4_MOUSE
θ value	2.60593e-15 (rank : 43)	NC score	0.446049 (rank : 241)
Query Neighborhood Hits	480	Target Neighborhood Hits	872	Shared Neighborhood Hits	288
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

HGS_MOUSE
θ value	3.40345e-15 (rank : 44)	NC score	0.253932 (rank : 300)
Query Neighborhood Hits	480	Target Neighborhood Hits	589	Shared Neighborhood Hits	66
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
θ value	4.44505e-15 (rank : 45)	NC score	0.257139 (rank : 296)
Query Neighborhood Hits	480	Target Neighborhood Hits	517	Shared Neighborhood Hits	66
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

ANKS1_HUMAN
θ value	7.58209e-15 (rank : 46)	NC score	0.777871 (rank : 70)
Query Neighborhood Hits	480	Target Neighborhood Hits	438	Shared Neighborhood Hits	300
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ASB14_MOUSE
θ value	9.90251e-15 (rank : 47)	NC score	0.778036 (rank : 68)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

MIB2_MOUSE
θ value	9.90251e-15 (rank : 48)	NC score	0.777880 (rank : 69)
Query Neighborhood Hits	480	Target Neighborhood Hits	409	Shared Neighborhood Hits	285
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PA2G6_HUMAN
θ value	9.90251e-15 (rank : 49)	NC score	0.807314 (rank : 32)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

TNI3K_HUMAN
θ value	9.90251e-15 (rank : 50)	NC score	0.411288 (rank : 249)
Query Neighborhood Hits	480	Target Neighborhood Hits	1084	Shared Neighborhood Hits	298
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANR21_HUMAN
θ value	1.29331e-14 (rank : 51)	NC score	0.721407 (rank : 132)
Query Neighborhood Hits	480	Target Neighborhood Hits	864	Shared Neighborhood Hits	303
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ASB15_MOUSE
θ value	1.29331e-14 (rank : 52)	NC score	0.779915 (rank : 63)
Query Neighborhood Hits	480	Target Neighborhood Hits	292	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

NOTC2_HUMAN
θ value	1.29331e-14 (rank : 53)	NC score	0.403159 (rank : 256)
Query Neighborhood Hits	480	Target Neighborhood Hits	1113	Shared Neighborhood Hits	287
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MYPT2_HUMAN
θ value	1.68911e-14 (rank : 54)	NC score	0.760720 (rank : 93)
Query Neighborhood Hits	480	Target Neighborhood Hits	707	Shared Neighborhood Hits	299
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

NOTC2_MOUSE
θ value	1.68911e-14 (rank : 55)	NC score	0.400538 (rank : 257)
Query Neighborhood Hits	480	Target Neighborhood Hits	1069	Shared Neighborhood Hits	284
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MIB2_HUMAN
θ value	2.20605e-14 (rank : 56)	NC score	0.780041 (rank : 61)
Query Neighborhood Hits	480	Target Neighborhood Hits	438	Shared Neighborhood Hits	292
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

NOTC1_HUMAN
θ value	2.20605e-14 (rank : 57)	NC score	0.405806 (rank : 255)
Query Neighborhood Hits	480	Target Neighborhood Hits	906	Shared Neighborhood Hits	285
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

POT14_HUMAN
θ value	2.20605e-14 (rank : 58)	NC score	0.709340 (rank : 139)
Query Neighborhood Hits	480	Target Neighborhood Hits	403	Shared Neighborhood Hits	273
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

POT15_HUMAN
θ value	2.20605e-14 (rank : 59)	NC score	0.722177 (rank : 131)
Query Neighborhood Hits	480	Target Neighborhood Hits	893	Shared Neighborhood Hits	303
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

UACA_MOUSE
θ value	2.88119e-14 (rank : 60)	NC score	0.476271 (rank : 231)
Query Neighborhood Hits	480	Target Neighborhood Hits	1620	Shared Neighborhood Hits	307
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

NOTC4_HUMAN
θ value	3.76295e-14 (rank : 61)	NC score	0.440007 (rank : 244)
Query Neighborhood Hits	480	Target Neighborhood Hits	905	Shared Neighborhood Hits	292
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

BCL3_MOUSE
θ value	4.91457e-14 (rank : 62)	NC score	0.810206 (rank : 29)
Query Neighborhood Hits	480	Target Neighborhood Hits	388	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CSKI1_HUMAN
θ value	6.41864e-14 (rank : 63)	NC score	0.745191 (rank : 116)
Query Neighborhood Hits	480	Target Neighborhood Hits	997	Shared Neighborhood Hits	293
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	6.41864e-14 (rank : 64)	NC score	0.743767 (rank : 118)
Query Neighborhood Hits	480	Target Neighborhood Hits	1031	Shared Neighborhood Hits	294
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NFKB1_MOUSE
θ value	6.41864e-14 (rank : 65)	NC score	0.705671 (rank : 141)
Query Neighborhood Hits	480	Target Neighborhood Hits	300	Shared Neighborhood Hits	269
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

RN5A_HUMAN
θ value	6.41864e-14 (rank : 66)	NC score	0.766886 (rank : 84)
Query Neighborhood Hits	480	Target Neighborhood Hits	608	Shared Neighborhood Hits	287
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

A20A1_HUMAN
θ value	1.09485e-13 (rank : 67)	NC score	0.662564 (rank : 167)
Query Neighborhood Hits	480	Target Neighborhood Hits	698	Shared Neighborhood Hits	283
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A3_HUMAN
θ value	1.09485e-13 (rank : 68)	NC score	0.664534 (rank : 164)
Query Neighborhood Hits	480	Target Neighborhood Hits	692	Shared Neighborhood Hits	284
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	1.09485e-13 (rank : 69)	NC score	0.659500 (rank : 172)
Query Neighborhood Hits	480	Target Neighborhood Hits	710	Shared Neighborhood Hits	284
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

POTE8_HUMAN
θ value	1.09485e-13 (rank : 70)	NC score	0.764080 (rank : 87)
Query Neighborhood Hits	480	Target Neighborhood Hits	337	Shared Neighborhood Hits	291
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

A20A2_HUMAN
θ value	1.42992e-13 (rank : 71)	NC score	0.662525 (rank : 168)
Query Neighborhood Hits	480	Target Neighborhood Hits	716	Shared Neighborhood Hits	286
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANKS1_MOUSE
θ value	1.42992e-13 (rank : 72)	NC score	0.763608 (rank : 88)
Query Neighborhood Hits	480	Target Neighborhood Hits	453	Shared Neighborhood Hits	293
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

PSD10_MOUSE
θ value	1.42992e-13 (rank : 73)	NC score	0.827456 (rank : 21)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

UACA_HUMAN
θ value	1.42992e-13 (rank : 74)	NC score	0.499263 (rank : 219)
Query Neighborhood Hits	480	Target Neighborhood Hits	1622	Shared Neighborhood Hits	313
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

CSKI2_HUMAN
θ value	2.43908e-13 (rank : 75)	NC score	0.747653 (rank : 114)
Query Neighborhood Hits	480	Target Neighborhood Hits	747	Shared Neighborhood Hits	295
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

EHMT2_HUMAN
θ value	2.43908e-13 (rank : 76)	NC score	0.741477 (rank : 120)
Query Neighborhood Hits	480	Target Neighborhood Hits	498	Shared Neighborhood Hits	300
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PSD10_HUMAN
θ value	2.43908e-13 (rank : 77)	NC score	0.827741 (rank : 20)
Query Neighborhood Hits	480	Target Neighborhood Hits	301	Shared Neighborhood Hits	291
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR18_HUMAN
θ value	3.18553e-13 (rank : 78)	NC score	0.619771 (rank : 189)
Query Neighborhood Hits	480	Target Neighborhood Hits	1106	Shared Neighborhood Hits	292
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

BCL3_HUMAN
θ value	3.18553e-13 (rank : 79)	NC score	0.814243 (rank : 27)
Query Neighborhood Hits	480	Target Neighborhood Hits	324	Shared Neighborhood Hits	289
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

CSKI2_MOUSE
θ value	3.18553e-13 (rank : 80)	NC score	0.748036 (rank : 111)
Query Neighborhood Hits	480	Target Neighborhood Hits	812	Shared Neighborhood Hits	291
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR16_HUMAN
θ value	4.16044e-13 (rank : 81)	NC score	0.832365 (rank : 13)
Query Neighborhood Hits	480	Target Neighborhood Hits	286	Shared Neighborhood Hits	279
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR42_MOUSE
θ value	5.43371e-13 (rank : 82)	NC score	0.806537 (rank : 35)
Query Neighborhood Hits	480	Target Neighborhood Hits	334	Shared Neighborhood Hits	284
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB5_HUMAN
θ value	5.43371e-13 (rank : 83)	NC score	0.761370 (rank : 90)
Query Neighborhood Hits	480	Target Neighborhood Hits	283	Shared Neighborhood Hits	270
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

EHMT2_MOUSE
θ value	5.43371e-13 (rank : 84)	NC score	0.726149 (rank : 129)
Query Neighborhood Hits	480	Target Neighborhood Hits	750	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PP16A_MOUSE
θ value	5.43371e-13 (rank : 85)	NC score	0.775257 (rank : 74)
Query Neighborhood Hits	480	Target Neighborhood Hits	318	Shared Neighborhood Hits	283
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

NFKB1_HUMAN
θ value	7.09661e-13 (rank : 86)	NC score	0.705490 (rank : 142)
Query Neighborhood Hits	480	Target Neighborhood Hits	306	Shared Neighborhood Hits	278
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANR26_MOUSE
θ value	9.26847e-13 (rank : 87)	NC score	0.465916 (rank : 234)
Query Neighborhood Hits	480	Target Neighborhood Hits	1554	Shared Neighborhood Hits	307
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB10_MOUSE
θ value	9.26847e-13 (rank : 88)	NC score	0.804372 (rank : 36)
Query Neighborhood Hits	480	Target Neighborhood Hits	301	Shared Neighborhood Hits	283
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANKR7_HUMAN
θ value	2.0648e-12 (rank : 89)	NC score	0.800036 (rank : 40)
Query Neighborhood Hits	480	Target Neighborhood Hits	286	Shared Neighborhood Hits	281
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR19_HUMAN
θ value	2.69671e-12 (rank : 90)	NC score	0.761030 (rank : 91)
Query Neighborhood Hits	480	Target Neighborhood Hits	276	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ASB5_MOUSE
θ value	2.69671e-12 (rank : 91)	NC score	0.758864 (rank : 96)
Query Neighborhood Hits	480	Target Neighborhood Hits	266	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

IKBE_MOUSE
θ value	3.52202e-12 (rank : 92)	NC score	0.782904 (rank : 55)
Query Neighborhood Hits	480	Target Neighborhood Hits	308	Shared Neighborhood Hits	279
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ASB7_HUMAN
θ value	6.00763e-12 (rank : 93)	NC score	0.807399 (rank : 31)
Query Neighborhood Hits	480	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	6.00763e-12 (rank : 94)	NC score	0.807172 (rank : 33)
Query Neighborhood Hits	480	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

MPP8_HUMAN
θ value	7.84624e-12 (rank : 95)	NC score	0.637389 (rank : 182)
Query Neighborhood Hits	480	Target Neighborhood Hits	948	Shared Neighborhood Hits	264
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

RN5A_MOUSE
θ value	7.84624e-12 (rank : 96)	NC score	0.714109 (rank : 137)
Query Neighborhood Hits	480	Target Neighborhood Hits	899	Shared Neighborhood Hits	297
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR42_HUMAN
θ value	1.02475e-11 (rank : 97)	NC score	0.800718 (rank : 38)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR26_HUMAN
θ value	1.33837e-11 (rank : 98)	NC score	0.449737 (rank : 240)
Query Neighborhood Hits	480	Target Neighborhood Hits	1614	Shared Neighborhood Hits	313
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

EHMT1_HUMAN
θ value	1.33837e-11 (rank : 99)	NC score	0.747716 (rank : 113)
Query Neighborhood Hits	480	Target Neighborhood Hits	417	Shared Neighborhood Hits	296
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANKR5_MOUSE
θ value	1.74796e-11 (rank : 100)	NC score	0.773240 (rank : 78)
Query Neighborhood Hits	480	Target Neighborhood Hits	298	Shared Neighborhood Hits	279
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

MYPT1_MOUSE
θ value	1.74796e-11 (rank : 101)	NC score	0.771312 (rank : 80)
Query Neighborhood Hits	480	Target Neighborhood Hits	539	Shared Neighborhood Hits	295
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANKR5_HUMAN
θ value	2.28291e-11 (rank : 102)	NC score	0.776038 (rank : 72)
Query Neighborhood Hits	480	Target Neighborhood Hits	297	Shared Neighborhood Hits	280
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

MYPT1_HUMAN
θ value	2.28291e-11 (rank : 103)	NC score	0.755732 (rank : 105)
Query Neighborhood Hits	480	Target Neighborhood Hits	723	Shared Neighborhood Hits	303
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

CTTB2_HUMAN
θ value	2.98157e-11 (rank : 104)	NC score	0.691688 (rank : 150)
Query Neighborhood Hits	480	Target Neighborhood Hits	1061	Shared Neighborhood Hits	312
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

IKBB_MOUSE
θ value	2.98157e-11 (rank : 105)	NC score	0.761008 (rank : 92)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ASB8_MOUSE
θ value	3.89403e-11 (rank : 106)	NC score	0.800517 (rank : 39)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

PP16A_HUMAN
θ value	3.89403e-11 (rank : 107)	NC score	0.766707 (rank : 85)
Query Neighborhood Hits	480	Target Neighborhood Hits	340	Shared Neighborhood Hits	278
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

AN36B_HUMAN
θ value	6.64225e-11 (rank : 108)	NC score	0.778723 (rank : 66)
Query Neighborhood Hits	480	Target Neighborhood Hits	294	Shared Neighborhood Hits	286
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR47_MOUSE
θ value	6.64225e-11 (rank : 109)	NC score	0.700873 (rank : 144)
Query Neighborhood Hits	480	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB10_HUMAN
θ value	6.64225e-11 (rank : 110)	NC score	0.802648 (rank : 37)
Query Neighborhood Hits	480	Target Neighborhood Hits	291	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

NFKB2_MOUSE
θ value	6.64225e-11 (rank : 111)	NC score	0.685210 (rank : 157)
Query Neighborhood Hits	480	Target Neighborhood Hits	326	Shared Neighborhood Hits	277
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

KLHL7_HUMAN
θ value	8.67504e-11 (rank : 112)	NC score	0.251291 (rank : 307)
Query Neighborhood Hits	480	Target Neighborhood Hits	176	Shared Neighborhood Hits	99
SwissProt Accessions	Q8IXQ5, Q9BQF8	Gene names	KLHL7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

KLHL7_MOUSE
θ value	8.67504e-11 (rank : 113)	NC score	0.251299 (rank : 306)
Query Neighborhood Hits	480	Target Neighborhood Hits	179	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BUL5, Q9CZP4	Gene names	Klhl7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

IKBE_HUMAN
θ value	1.133e-10 (rank : 114)	NC score	0.766498 (rank : 86)
Query Neighborhood Hits	480	Target Neighborhood Hits	288	Shared Neighborhood Hits	269
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANR12_HUMAN
θ value	1.47974e-10 (rank : 115)	NC score	0.663266 (rank : 166)
Query Neighborhood Hits	480	Target Neighborhood Hits	1081	Shared Neighborhood Hits	297
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

WDFY3_HUMAN
θ value	1.47974e-10 (rank : 116)	NC score	0.171853 (rank : 415)
Query Neighborhood Hits	480	Target Neighborhood Hits	348	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
θ value	1.47974e-10 (rank : 117)	NC score	0.172434 (rank : 414)
Query Neighborhood Hits	480	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

ANKS3_HUMAN
θ value	2.52405e-10 (rank : 118)	NC score	0.779969 (rank : 62)
Query Neighborhood Hits	480	Target Neighborhood Hits	355	Shared Neighborhood Hits	277
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB8_HUMAN
θ value	2.52405e-10 (rank : 119)	NC score	0.799456 (rank : 41)
Query Neighborhood Hits	480	Target Neighborhood Hits	294	Shared Neighborhood Hits	285
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

NFKB2_HUMAN
θ value	4.30538e-10 (rank : 120)	NC score	0.695320 (rank : 146)
Query Neighborhood Hits	480	Target Neighborhood Hits	325	Shared Neighborhood Hits	281
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NOTC1_MOUSE
θ value	4.30538e-10 (rank : 121)	NC score	0.349536 (rank : 266)
Query Neighborhood Hits	480	Target Neighborhood Hits	916	Shared Neighborhood Hits	261
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KLHL8_MOUSE
θ value	5.62301e-10 (rank : 122)	NC score	0.243576 (rank : 314)
Query Neighborhood Hits	480	Target Neighborhood Hits	183	Shared Neighborhood Hits	104
SwissProt Accessions	P59280	Gene names	Klhl8
Domain Architecture
Description	Kelch-like protein 8.

ZFY28_HUMAN
θ value	5.62301e-10 (rank : 123)	NC score	0.299942 (rank : 282)
Query Neighborhood Hits	480	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ANKS3_MOUSE
θ value	7.34386e-10 (rank : 124)	NC score	0.780597 (rank : 57)
Query Neighborhood Hits	480	Target Neighborhood Hits	355	Shared Neighborhood Hits	278
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB9_HUMAN
θ value	9.59137e-10 (rank : 125)	NC score	0.756057 (rank : 104)
Query Neighborhood Hits	480	Target Neighborhood Hits	267	Shared Neighborhood Hits	255
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MTMR3_HUMAN
θ value	1.25267e-09 (rank : 126)	NC score	0.171052 (rank : 416)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	56
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

RUFY1_HUMAN
θ value	1.25267e-09 (rank : 127)	NC score	0.188304 (rank : 396)
Query Neighborhood Hits	480	Target Neighborhood Hits	848	Shared Neighborhood Hits	81
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

EEA1_MOUSE
θ value	1.63604e-09 (rank : 128)	NC score	0.129571 (rank : 439)
Query Neighborhood Hits	480	Target Neighborhood Hits	1637	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ZDH17_HUMAN
θ value	1.63604e-09 (rank : 129)	NC score	0.693142 (rank : 148)
Query Neighborhood Hits	480	Target Neighborhood Hits	334	Shared Neighborhood Hits	280
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ZFY21_HUMAN
θ value	1.63604e-09 (rank : 130)	NC score	0.305079 (rank : 281)
Query Neighborhood Hits	480	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
θ value	1.63604e-09 (rank : 131)	NC score	0.305960 (rank : 280)
Query Neighborhood Hits	480	Target Neighborhood Hits	72	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ANKS6_HUMAN
θ value	2.13673e-09 (rank : 132)	NC score	0.780242 (rank : 60)
Query Neighborhood Hits	480	Target Neighborhood Hits	411	Shared Neighborhood Hits	294
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ASB11_MOUSE
θ value	2.13673e-09 (rank : 133)	NC score	0.754701 (rank : 106)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	257
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

OSBL1_HUMAN
θ value	2.13673e-09 (rank : 134)	NC score	0.619887 (rank : 188)
Query Neighborhood Hits	480	Target Neighborhood Hits	368	Shared Neighborhood Hits	283
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

RUFY1_MOUSE
θ value	2.13673e-09 (rank : 135)	NC score	0.184248 (rank : 403)
Query Neighborhood Hits	480	Target Neighborhood Hits	765	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

ANR23_HUMAN
θ value	2.79066e-09 (rank : 136)	NC score	0.795121 (rank : 42)
Query Neighborhood Hits	480	Target Neighborhood Hits	291	Shared Neighborhood Hits	284
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ASB13_HUMAN
θ value	2.79066e-09 (rank : 137)	NC score	0.788940 (rank : 46)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

CDN2D_MOUSE
θ value	2.79066e-09 (rank : 138)	NC score	0.767588 (rank : 83)
Query Neighborhood Hits	480	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

IKBB_HUMAN
θ value	2.79066e-09 (rank : 139)	NC score	0.757174 (rank : 99)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

RUFY2_MOUSE
θ value	2.79066e-09 (rank : 140)	NC score	0.191517 (rank : 393)
Query Neighborhood Hits	480	Target Neighborhood Hits	820	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

ZDH17_MOUSE
θ value	2.79066e-09 (rank : 141)	NC score	0.687834 (rank : 154)
Query Neighborhood Hits	480	Target Neighborhood Hits	328	Shared Neighborhood Hits	275
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANKR2_MOUSE
θ value	3.64472e-09 (rank : 142)	NC score	0.788397 (rank : 47)
Query Neighborhood Hits	480	Target Neighborhood Hits	312	Shared Neighborhood Hits	287
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR47_HUMAN
θ value	3.64472e-09 (rank : 143)	NC score	0.682283 (rank : 159)
Query Neighborhood Hits	480	Target Neighborhood Hits	369	Shared Neighborhood Hits	254
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANKS6_MOUSE
θ value	4.76016e-09 (rank : 144)	NC score	0.780699 (rank : 56)
Query Neighborhood Hits	480	Target Neighborhood Hits	435	Shared Neighborhood Hits	293
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASB13_MOUSE
θ value	4.76016e-09 (rank : 145)	NC score	0.789718 (rank : 44)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB16_HUMAN
θ value	4.76016e-09 (rank : 146)	NC score	0.772885 (rank : 79)
Query Neighborhood Hits	480	Target Neighborhood Hits	286	Shared Neighborhood Hits	273
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

IKBA_MOUSE
θ value	4.76016e-09 (rank : 147)	NC score	0.770356 (rank : 81)
Query Neighborhood Hits	480	Target Neighborhood Hits	283	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

CDN2C_MOUSE
θ value	6.21693e-09 (rank : 148)	NC score	0.775138 (rank : 75)
Query Neighborhood Hits	480	Target Neighborhood Hits	270	Shared Neighborhood Hits	269
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

EEA1_HUMAN
θ value	6.21693e-09 (rank : 149)	NC score	0.123875 (rank : 442)
Query Neighborhood Hits	480	Target Neighborhood Hits	1796	Shared Neighborhood Hits	109
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

KBTB3_HUMAN
θ value	6.21693e-09 (rank : 150)	NC score	0.250274 (rank : 310)
Query Neighborhood Hits	480	Target Neighborhood Hits	176	Shared Neighborhood Hits	101
SwissProt Accessions	Q8NAB2, Q86X38, Q96NK5	Gene names	KBTBD3, BKLHD3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KBTBA_HUMAN
θ value	6.21693e-09 (rank : 151)	NC score	0.249239 (rank : 311)
Query Neighborhood Hits	480	Target Neighborhood Hits	184	Shared Neighborhood Hits	98
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

KLHL8_HUMAN
θ value	6.21693e-09 (rank : 152)	NC score	0.242391 (rank : 315)
Query Neighborhood Hits	480	Target Neighborhood Hits	180	Shared Neighborhood Hits	104
SwissProt Accessions	Q9P2G9	Gene names	KLHL8, KIAA1378
Domain Architecture
Description	Kelch-like protein 8.

SHAN1_HUMAN
θ value	6.21693e-09 (rank : 153)	NC score	0.659916 (rank : 170)
Query Neighborhood Hits	480	Target Neighborhood Hits	1041	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ZDH13_HUMAN
θ value	6.21693e-09 (rank : 154)	NC score	0.692724 (rank : 149)
Query Neighborhood Hits	480	Target Neighborhood Hits	322	Shared Neighborhood Hits	278
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

FGD6_HUMAN
θ value	8.11959e-09 (rank : 155)	NC score	0.209204 (rank : 373)
Query Neighborhood Hits	480	Target Neighborhood Hits	237	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

IKBA_HUMAN
θ value	8.11959e-09 (rank : 156)	NC score	0.777750 (rank : 71)
Query Neighborhood Hits	480	Target Neighborhood Hits	280	Shared Neighborhood Hits	276
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

KLHL1_HUMAN
θ value	8.11959e-09 (rank : 157)	NC score	0.229024 (rank : 332)
Query Neighborhood Hits	480	Target Neighborhood Hits	195	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NR64, Q5VZ64, Q9H4X4, Q9NR65, Q9P238	Gene names	KLHL1, KIAA1490
Domain Architecture
Description	Kelch-like protein 1.

KLHL1_MOUSE
θ value	8.11959e-09 (rank : 158)	NC score	0.229494 (rank : 328)
Query Neighborhood Hits	480	Target Neighborhood Hits	193	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

RUFY2_HUMAN
θ value	8.11959e-09 (rank : 159)	NC score	0.158637 (rank : 424)
Query Neighborhood Hits	480	Target Neighborhood Hits	1208	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SPOP_HUMAN
θ value	8.11959e-09 (rank : 160)	NC score	0.256715 (rank : 297)
Query Neighborhood Hits	480	Target Neighborhood Hits	168	Shared Neighborhood Hits	102
SwissProt Accessions	O43791	Gene names	SPOP
Domain Architecture
Description	Speckle-type POZ protein.

SPOP_MOUSE
θ value	8.11959e-09 (rank : 161)	NC score	0.256715 (rank : 298)
Query Neighborhood Hits	480	Target Neighborhood Hits	168	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZWS8	Gene names	Spop, Pcif1
Domain Architecture	No domain graphic available
Description	Speckle-type POZ protein (PDX-1 C-terminal-interacting factor 1) (PCIF1).

CDN2C_HUMAN
θ value	1.06045e-08 (rank : 162)	NC score	0.773899 (rank : 77)
Query Neighborhood Hits	480	Target Neighborhood Hits	262	Shared Neighborhood Hits	261
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

KRIT1_MOUSE
θ value	1.06045e-08 (rank : 163)	NC score	0.642051 (rank : 181)
Query Neighborhood Hits	480	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PKHF2_HUMAN
θ value	1.06045e-08 (rank : 164)	NC score	0.277392 (rank : 289)
Query Neighborhood Hits	480	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	1.06045e-08 (rank : 165)	NC score	0.277581 (rank : 288)
Query Neighborhood Hits	480	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

KLHL5_HUMAN
θ value	1.38499e-08 (rank : 166)	NC score	0.231871 (rank : 323)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	104
SwissProt Accessions	Q96PQ7, Q86XW0, Q9NUK3, Q9NV27, Q9NVA9, Q9Y2X2	Gene names	KLHL5
Domain Architecture
Description	Kelch-like protein 5.

CDN2D_HUMAN
θ value	1.80886e-08 (rank : 167)	NC score	0.768500 (rank : 82)
Query Neighborhood Hits	480	Target Neighborhood Hits	268	Shared Neighborhood Hits	265
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

GABP2_HUMAN
θ value	1.80886e-08 (rank : 168)	NC score	0.778174 (rank : 67)
Query Neighborhood Hits	480	Target Neighborhood Hits	454	Shared Neighborhood Hits	293
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ZFY16_HUMAN
θ value	2.36244e-08 (rank : 169)	NC score	0.252027 (rank : 305)
Query Neighborhood Hits	480	Target Neighborhood Hits	125	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
θ value	2.36244e-08 (rank : 170)	NC score	0.256324 (rank : 299)
Query Neighborhood Hits	480	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

GABP2_MOUSE
θ value	3.08544e-08 (rank : 171)	NC score	0.779311 (rank : 64)
Query Neighborhood Hits	480	Target Neighborhood Hits	429	Shared Neighborhood Hits	292
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

SNCAP_HUMAN
θ value	3.08544e-08 (rank : 172)	NC score	0.681509 (rank : 160)
Query Neighborhood Hits	480	Target Neighborhood Hits	313	Shared Neighborhood Hits	237
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANKR1_MOUSE
θ value	4.0297e-08 (rank : 173)	NC score	0.787586 (rank : 48)
Query Neighborhood Hits	480	Target Neighborhood Hits	316	Shared Neighborhood Hits	289
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB9_MOUSE
θ value	4.0297e-08 (rank : 174)	NC score	0.743938 (rank : 117)
Query Neighborhood Hits	480	Target Neighborhood Hits	257	Shared Neighborhood Hits	249
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

PP16B_MOUSE
θ value	5.26297e-08 (rank : 175)	NC score	0.756745 (rank : 100)
Query Neighborhood Hits	480	Target Neighborhood Hits	302	Shared Neighborhood Hits	282
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

WDFY2_HUMAN
θ value	5.26297e-08 (rank : 176)	NC score	0.176132 (rank : 407)
Query Neighborhood Hits	480	Target Neighborhood Hits	332	Shared Neighborhood Hits	50
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDFY2_MOUSE
θ value	5.26297e-08 (rank : 177)	NC score	0.177432 (rank : 406)
Query Neighborhood Hits	480	Target Neighborhood Hits	337	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

KBTB4_MOUSE
θ value	8.97725e-08 (rank : 178)	NC score	0.253731 (rank : 301)
Query Neighborhood Hits	480	Target Neighborhood Hits	182	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R179, Q9CQX1	Gene names	Kbtbd4, Bklhd4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

ANKR2_HUMAN
θ value	1.17247e-07 (rank : 179)	NC score	0.787093 (rank : 51)
Query Neighborhood Hits	480	Target Neighborhood Hits	321	Shared Neighborhood Hits	288
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASB16_MOUSE
θ value	1.17247e-07 (rank : 180)	NC score	0.778825 (rank : 65)
Query Neighborhood Hits	480	Target Neighborhood Hits	306	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

OSBL1_MOUSE
θ value	1.17247e-07 (rank : 181)	NC score	0.606258 (rank : 191)
Query Neighborhood Hits	480	Target Neighborhood Hits	336	Shared Neighborhood Hits	282
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PP16B_HUMAN
θ value	1.17247e-07 (rank : 182)	NC score	0.757563 (rank : 97)
Query Neighborhood Hits	480	Target Neighborhood Hits	307	Shared Neighborhood Hits	282
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ANR25_HUMAN
θ value	1.53129e-07 (rank : 183)	NC score	0.659865 (rank : 171)
Query Neighborhood Hits	480	Target Neighborhood Hits	350	Shared Neighborhood Hits	255
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR25_MOUSE
θ value	1.53129e-07 (rank : 184)	NC score	0.647324 (rank : 178)
Query Neighborhood Hits	480	Target Neighborhood Hits	398	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

KLHL3_HUMAN
θ value	1.53129e-07 (rank : 185)	NC score	0.233021 (rank : 322)
Query Neighborhood Hits	480	Target Neighborhood Hits	187	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UH77, Q9UH75, Q9UH76, Q9ULU0, Q9Y6V6	Gene names	KLHL3, KIAA1129
Domain Architecture
Description	Kelch-like protein 3.

WDFY1_HUMAN
θ value	1.53129e-07 (rank : 186)	NC score	0.178625 (rank : 405)
Query Neighborhood Hits	480	Target Neighborhood Hits	305	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

ASB11_HUMAN
θ value	1.99992e-07 (rank : 187)	NC score	0.751627 (rank : 109)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

FGD5_MOUSE
θ value	1.99992e-07 (rank : 188)	NC score	0.212778 (rank : 369)
Query Neighborhood Hits	480	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

ILK1_HUMAN
θ value	1.99992e-07 (rank : 189)	NC score	0.463219 (rank : 235)
Query Neighborhood Hits	480	Target Neighborhood Hits	857	Shared Neighborhood Hits	286
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	1.99992e-07 (rank : 190)	NC score	0.479697 (rank : 229)
Query Neighborhood Hits	480	Target Neighborhood Hits	848	Shared Neighborhood Hits	286
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

KBTB2_HUMAN
θ value	1.99992e-07 (rank : 191)	NC score	0.247346 (rank : 312)
Query Neighborhood Hits	480	Target Neighborhood Hits	179	Shared Neighborhood Hits	104
SwissProt Accessions	Q8IY47, Q86Y62, Q9P239, Q9UFM7	Gene names	KBTBD2, BKLHD1, KIAA1489
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1).

KBTB4_HUMAN
θ value	1.99992e-07 (rank : 192)	NC score	0.253455 (rank : 302)
Query Neighborhood Hits	480	Target Neighborhood Hits	187	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NVX7, Q6IA85, Q9BUC3, Q9NV76	Gene names	KBTBD4, BKLHD4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

ZDH13_MOUSE
θ value	1.99992e-07 (rank : 193)	NC score	0.686539 (rank : 155)
Query Neighborhood Hits	480	Target Neighborhood Hits	329	Shared Neighborhood Hits	280
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANKR1_HUMAN
θ value	2.61198e-07 (rank : 194)	NC score	0.787322 (rank : 49)
Query Neighborhood Hits	480	Target Neighborhood Hits	308	Shared Neighborhood Hits	281
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANR38_HUMAN
θ value	2.61198e-07 (rank : 195)	NC score	0.650950 (rank : 174)
Query Neighborhood Hits	480	Target Neighborhood Hits	443	Shared Neighborhood Hits	247
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

FGD2_MOUSE
θ value	2.61198e-07 (rank : 196)	NC score	0.189206 (rank : 394)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

KRIT1_HUMAN
θ value	2.61198e-07 (rank : 197)	NC score	0.636104 (rank : 183)
Query Neighborhood Hits	480	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ANR10_HUMAN
θ value	3.41135e-07 (rank : 198)	NC score	0.745718 (rank : 115)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	267
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR11_HUMAN
θ value	3.41135e-07 (rank : 199)	NC score	0.678203 (rank : 161)
Query Neighborhood Hits	480	Target Neighborhood Hits	1289	Shared Neighborhood Hits	292
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ASB4_HUMAN
θ value	3.41135e-07 (rank : 200)	NC score	0.759410 (rank : 95)
Query Neighborhood Hits	480	Target Neighborhood Hits	264	Shared Neighborhood Hits	259
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_MOUSE
θ value	3.41135e-07 (rank : 201)	NC score	0.759881 (rank : 94)
Query Neighborhood Hits	480	Target Neighborhood Hits	265	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ILK_MOUSE
θ value	3.41135e-07 (rank : 202)	NC score	0.460772 (rank : 236)
Query Neighborhood Hits	480	Target Neighborhood Hits	858	Shared Neighborhood Hits	285
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

FYV1_HUMAN
θ value	4.45536e-07 (rank : 203)	NC score	0.205671 (rank : 381)
Query Neighborhood Hits	480	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	4.45536e-07 (rank : 204)	NC score	0.205967 (rank : 380)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

IPP_HUMAN
θ value	4.45536e-07 (rank : 205)	NC score	0.227764 (rank : 338)
Query Neighborhood Hits	480	Target Neighborhood Hits	186	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y573	Gene names	IPP
Domain Architecture
Description	Actin-binding protein IPP (MIPP protein).

KLH17_HUMAN
θ value	4.45536e-07 (rank : 206)	NC score	0.231480 (rank : 324)
Query Neighborhood Hits	480	Target Neighborhood Hits	201	Shared Neighborhood Hits	104
SwissProt Accessions	Q6TDP4	Gene names	KLHL17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

KLH17_MOUSE
θ value	4.45536e-07 (rank : 207)	NC score	0.231071 (rank : 325)
Query Neighborhood Hits	480	Target Neighborhood Hits	200	Shared Neighborhood Hits	103
SwissProt Accessions	Q6TDP3	Gene names	Klhl17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

TRPV5_MOUSE
θ value	4.45536e-07 (rank : 208)	NC score	0.518298 (rank : 212)
Query Neighborhood Hits	480	Target Neighborhood Hits	278	Shared Neighborhood Hits	253
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_MOUSE
θ value	4.45536e-07 (rank : 209)	NC score	0.563657 (rank : 198)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	260
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ACBD6_MOUSE
θ value	5.81887e-07 (rank : 210)	NC score	0.736997 (rank : 125)
Query Neighborhood Hits	480	Target Neighborhood Hits	305	Shared Neighborhood Hits	291
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

PKHF1_HUMAN
θ value	7.59969e-07 (rank : 211)	NC score	0.272695 (rank : 291)
Query Neighborhood Hits	480	Target Neighborhood Hits	76	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

ANR49_MOUSE
θ value	9.92553e-07 (rank : 212)	NC score	0.780336 (rank : 58)
Query Neighborhood Hits	480	Target Neighborhood Hits	285	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

BTBD1_HUMAN
θ value	9.92553e-07 (rank : 213)	NC score	0.239487 (rank : 316)
Query Neighborhood Hits	480	Target Neighborhood Hits	127	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H0C5, Q9BX71, Q9NWN4	Gene names	BTBD1, C15orf1
Domain Architecture
Description	BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A- transactivated protein 8) (NS5ATP8).

FGD5_HUMAN
θ value	9.92553e-07 (rank : 214)	NC score	0.207259 (rank : 376)
Query Neighborhood Hits	480	Target Neighborhood Hits	235	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

KBTB3_MOUSE
θ value	9.92553e-07 (rank : 215)	NC score	0.245628 (rank : 313)
Query Neighborhood Hits	480	Target Neighborhood Hits	176	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BHI4, Q8BNJ8	Gene names	Kbtbd3, Bklhd3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KLH12_HUMAN
θ value	9.92553e-07 (rank : 216)	NC score	0.227857 (rank : 337)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	103
SwissProt Accessions	Q53G59, Q9HBX5	Gene names	KLHL12, C3IP1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

KLHL4_HUMAN
θ value	9.92553e-07 (rank : 217)	NC score	0.229001 (rank : 333)
Query Neighborhood Hits	480	Target Neighborhood Hits	212	Shared Neighborhood Hits	102
SwissProt Accessions	Q9C0H6, Q9Y3J5	Gene names	KLHL4, KIAA1687
Domain Architecture
Description	Kelch-like protein 4.

ANR15_HUMAN
θ value	1.29631e-06 (rank : 218)	NC score	0.691052 (rank : 151)
Query Neighborhood Hits	480	Target Neighborhood Hits	478	Shared Neighborhood Hits	279
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

BCOR_MOUSE
θ value	1.29631e-06 (rank : 219)	NC score	0.656076 (rank : 173)
Query Neighborhood Hits	480	Target Neighborhood Hits	521	Shared Neighborhood Hits	278
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

FGD6_MOUSE
θ value	1.29631e-06 (rank : 220)	NC score	0.200299 (rank : 385)
Query Neighborhood Hits	480	Target Neighborhood Hits	282	Shared Neighborhood Hits	56
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

LZTR1_HUMAN
θ value	1.29631e-06 (rank : 221)	NC score	0.211275 (rank : 371)
Query Neighborhood Hits	480	Target Neighborhood Hits	196	Shared Neighborhood Hits	100
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

ANR49_HUMAN
θ value	1.69304e-06 (rank : 222)	NC score	0.775645 (rank : 73)
Query Neighborhood Hits	480	Target Neighborhood Hits	282	Shared Neighborhood Hits	275
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

BARD1_MOUSE
θ value	1.69304e-06 (rank : 223)	NC score	0.719429 (rank : 133)
Query Neighborhood Hits	480	Target Neighborhood Hits	411	Shared Neighborhood Hits	281
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BCOR_HUMAN
θ value	1.69304e-06 (rank : 224)	NC score	0.647850 (rank : 177)
Query Neighborhood Hits	480	Target Neighborhood Hits	609	Shared Neighborhood Hits	279
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

GABP3_MOUSE
θ value	1.69304e-06 (rank : 225)	NC score	0.774359 (rank : 76)
Query Neighborhood Hits	480	Target Neighborhood Hits	330	Shared Neighborhood Hits	279
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

PKHF1_MOUSE
θ value	1.69304e-06 (rank : 226)	NC score	0.268772 (rank : 293)
Query Neighborhood Hits	480	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

FGD2_HUMAN
θ value	2.21117e-06 (rank : 227)	NC score	0.186005 (rank : 400)
Query Neighborhood Hits	480	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

KLH12_MOUSE
θ value	2.21117e-06 (rank : 228)	NC score	0.227478 (rank : 340)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BZM0, Q8K225	Gene names	Klhl12, C3ip1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

ABTB2_MOUSE
θ value	2.88788e-06 (rank : 229)	NC score	0.646590 (rank : 179)
Query Neighborhood Hits	480	Target Neighborhood Hits	414	Shared Neighborhood Hits	310
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR23_MOUSE
θ value	2.88788e-06 (rank : 230)	NC score	0.789070 (rank : 45)
Query Neighborhood Hits	480	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASZ1_MOUSE
θ value	2.88788e-06 (rank : 231)	NC score	0.756536 (rank : 102)
Query Neighborhood Hits	480	Target Neighborhood Hits	319	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

BTBD5_MOUSE
θ value	2.88788e-06 (rank : 232)	NC score	0.230993 (rank : 326)
Query Neighborhood Hits	480	Target Neighborhood Hits	189	Shared Neighborhood Hits	104
SwissProt Accessions	Q9CR40, Q9CYV0	Gene names	Btbd5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

POT22_HUMAN
θ value	2.88788e-06 (rank : 233)	NC score	0.661394 (rank : 169)
Query Neighborhood Hits	480	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANR32_HUMAN
θ value	3.77169e-06 (rank : 234)	NC score	0.711711 (rank : 138)
Query Neighborhood Hits	480	Target Neighborhood Hits	270	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR46_HUMAN
θ value	3.77169e-06 (rank : 235)	NC score	0.756302 (rank : 103)
Query Neighborhood Hits	480	Target Neighborhood Hits	281	Shared Neighborhood Hits	274
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ZFYV1_MOUSE
θ value	3.77169e-06 (rank : 236)	NC score	0.236814 (rank : 317)
Query Neighborhood Hits	480	Target Neighborhood Hits	153	Shared Neighborhood Hits	56
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ZFYV9_HUMAN
θ value	3.77169e-06 (rank : 237)	NC score	0.252957 (rank : 303)
Query Neighborhood Hits	480	Target Neighborhood Hits	134	Shared Neighborhood Hits	57
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

ACBD6_HUMAN
θ value	4.92598e-06 (rank : 238)	NC score	0.732422 (rank : 127)
Query Neighborhood Hits	480	Target Neighborhood Hits	304	Shared Neighborhood Hits	287
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

AN36A_HUMAN
θ value	4.92598e-06 (rank : 239)	NC score	0.741178 (rank : 122)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	271
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR10_MOUSE
θ value	4.92598e-06 (rank : 240)	NC score	0.741969 (rank : 119)
Query Neighborhood Hits	480	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR38_MOUSE
θ value	4.92598e-06 (rank : 241)	NC score	0.629618 (rank : 184)
Query Neighborhood Hits	480	Target Neighborhood Hits	512	Shared Neighborhood Hits	241
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

BTBD2_HUMAN
θ value	4.92598e-06 (rank : 242)	NC score	0.224240 (rank : 351)
Query Neighborhood Hits	480	Target Neighborhood Hits	161	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

BTBD9_MOUSE
θ value	4.92598e-06 (rank : 243)	NC score	0.252662 (rank : 304)
Query Neighborhood Hits	480	Target Neighborhood Hits	165	Shared Neighborhood Hits	97
SwissProt Accessions	Q8C726	Gene names	Btbd9
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

KLHL2_HUMAN
θ value	4.92598e-06 (rank : 244)	NC score	0.229493 (rank : 329)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	O95198, Q8N484, Q8TBH5	Gene names	KLHL2
Domain Architecture
Description	Kelch-like protein 2 (Actin-binding protein Mayven).

BTBD5_HUMAN
θ value	6.43352e-06 (rank : 245)	NC score	0.229733 (rank : 327)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NXS3	Gene names	BTBD5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

LZTR1_MOUSE
θ value	6.43352e-06 (rank : 246)	NC score	0.206714 (rank : 378)
Query Neighborhood Hits	480	Target Neighborhood Hits	200	Shared Neighborhood Hits	101
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

TRPV5_HUMAN
θ value	6.43352e-06 (rank : 247)	NC score	0.493818 (rank : 223)
Query Neighborhood Hits	480	Target Neighborhood Hits	261	Shared Neighborhood Hits	231
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR46_MOUSE
θ value	8.40245e-06 (rank : 248)	NC score	0.747937 (rank : 112)
Query Neighborhood Hits	480	Target Neighborhood Hits	274	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ABTB2_HUMAN
θ value	1.09739e-05 (rank : 249)	NC score	0.649446 (rank : 175)
Query Neighborhood Hits	480	Target Neighborhood Hits	391	Shared Neighborhood Hits	310
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR39_HUMAN
θ value	1.09739e-05 (rank : 250)	NC score	0.784927 (rank : 54)
Query Neighborhood Hits	480	Target Neighborhood Hits	285	Shared Neighborhood Hits	283
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

RCBT1_HUMAN
θ value	1.09739e-05 (rank : 251)	NC score	0.187510 (rank : 399)
Query Neighborhood Hits	480	Target Neighborhood Hits	158	Shared Neighborhood Hits	92
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

RCBT1_MOUSE
θ value	1.09739e-05 (rank : 252)	NC score	0.187751 (rank : 398)
Query Neighborhood Hits	480	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

BTBD6_MOUSE
θ value	1.43324e-05 (rank : 253)	NC score	0.221444 (rank : 355)
Query Neighborhood Hits	480	Target Neighborhood Hits	125	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K2J9	Gene names	Btbd6
Domain Architecture
Description	BTB/POZ domain-containing protein 6.

CT086_HUMAN
θ value	1.43324e-05 (rank : 254)	NC score	0.753955 (rank : 107)
Query Neighborhood Hits	480	Target Neighborhood Hits	277	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

FYCO1_HUMAN
θ value	1.43324e-05 (rank : 255)	NC score	0.135332 (rank : 438)
Query Neighborhood Hits	480	Target Neighborhood Hits	1149	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FGD1_MOUSE
θ value	1.87187e-05 (rank : 256)	NC score	0.173901 (rank : 413)
Query Neighborhood Hits	480	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

TRPV1_MOUSE
θ value	1.87187e-05 (rank : 257)	NC score	0.289945 (rank : 284)
Query Neighborhood Hits	480	Target Neighborhood Hits	189	Shared Neighborhood Hits	162
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ZFYV1_HUMAN
θ value	1.87187e-05 (rank : 258)	NC score	0.234881 (rank : 319)
Query Neighborhood Hits	480	Target Neighborhood Hits	166	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ASB6_MOUSE
θ value	2.44474e-05 (rank : 259)	NC score	0.705772 (rank : 140)
Query Neighborhood Hits	480	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

BTBD1_MOUSE
θ value	2.44474e-05 (rank : 260)	NC score	0.223336 (rank : 352)
Query Neighborhood Hits	480	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	P58544, Q8BTZ0, Q8K0J0	Gene names	Btbd1, Gsrp
Domain Architecture
Description	BTB/POZ domain-containing protein 1 (Glucose signal repressing protein).

FGD1_HUMAN
θ value	2.44474e-05 (rank : 261)	NC score	0.175006 (rank : 409)
Query Neighborhood Hits	480	Target Neighborhood Hits	367	Shared Neighborhood Hits	64
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

KLHL2_MOUSE
θ value	2.44474e-05 (rank : 262)	NC score	0.228483 (rank : 335)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	104
SwissProt Accessions	Q8JZP3, Q8CCU0, Q8R3U4	Gene names	Klhl2
Domain Architecture	No domain graphic available
Description	Kelch-like protein 2.

TDPZ4_MOUSE
θ value	2.44474e-05 (rank : 263)	NC score	0.235114 (rank : 318)
Query Neighborhood Hits	480	Target Neighborhood Hits	162	Shared Neighborhood Hits	101
SwissProt Accessions	Q6YCH2	Gene names	Tdpoz4
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 4.

ANR39_MOUSE
θ value	3.19293e-05 (rank : 264)	NC score	0.780303 (rank : 59)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

RFXK_HUMAN
θ value	3.19293e-05 (rank : 265)	NC score	0.740961 (rank : 123)
Query Neighborhood Hits	480	Target Neighborhood Hits	282	Shared Neighborhood Hits	264
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANR32_MOUSE
θ value	4.1701e-05 (rank : 266)	NC score	0.697207 (rank : 145)
Query Neighborhood Hits	480	Target Neighborhood Hits	285	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR37_MOUSE
θ value	4.1701e-05 (rank : 267)	NC score	0.663526 (rank : 165)
Query Neighborhood Hits	480	Target Neighborhood Hits	237	Shared Neighborhood Hits	236
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ASPP1_HUMAN
θ value	4.1701e-05 (rank : 268)	NC score	0.508351 (rank : 216)
Query Neighborhood Hits	480	Target Neighborhood Hits	956	Shared Neighborhood Hits	275
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	4.1701e-05 (rank : 269)	NC score	0.491948 (rank : 227)
Query Neighborhood Hits	480	Target Neighborhood Hits	1244	Shared Neighborhood Hits	281
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BARD1_HUMAN
θ value	4.1701e-05 (rank : 270)	NC score	0.719345 (rank : 134)
Query Neighborhood Hits	480	Target Neighborhood Hits	427	Shared Neighborhood Hits	288
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BTBD9_HUMAN
θ value	4.1701e-05 (rank : 271)	NC score	0.250936 (rank : 308)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	99
SwissProt Accessions	Q96Q07, Q96M00	Gene names	BTBD9, KIAA1880
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

FGD4_HUMAN
θ value	4.1701e-05 (rank : 272)	NC score	0.174748 (rank : 411)
Query Neighborhood Hits	480	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FYCO1_MOUSE
θ value	4.1701e-05 (rank : 273)	NC score	0.123168 (rank : 444)
Query Neighborhood Hits	480	Target Neighborhood Hits	1059	Shared Neighborhood Hits	84
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

TRPV3_HUMAN
θ value	4.1701e-05 (rank : 274)	NC score	0.287731 (rank : 285)
Query Neighborhood Hits	480	Target Neighborhood Hits	198	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV6_HUMAN
θ value	4.1701e-05 (rank : 275)	NC score	0.492464 (rank : 226)
Query Neighborhood Hits	480	Target Neighborhood Hits	262	Shared Neighborhood Hits	233
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

ANR22_HUMAN
θ value	5.44631e-05 (rank : 276)	NC score	0.756596 (rank : 101)
Query Neighborhood Hits	480	Target Neighborhood Hits	243	Shared Neighborhood Hits	243
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

CENB2_HUMAN
θ value	5.44631e-05 (rank : 277)	NC score	0.498466 (rank : 220)
Query Neighborhood Hits	480	Target Neighborhood Hits	425	Shared Neighborhood Hits	260
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ENC1_HUMAN
θ value	5.44631e-05 (rank : 278)	NC score	0.229027 (rank : 331)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	100
SwissProt Accessions	O14682, O75464, Q9UPG9	Gene names	ENC1, NRPB, PIG10
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1) (p53-induced protein 10) (Nuclear matrix protein NRP/B).

ENC1_MOUSE
θ value	5.44631e-05 (rank : 279)	NC score	0.228918 (rank : 334)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	100
SwissProt Accessions	O35709	Gene names	Enc1, Enc-1
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1).

FGD4_MOUSE
θ value	5.44631e-05 (rank : 280)	NC score	0.176002 (rank : 408)
Query Neighborhood Hits	480	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

IASPP_HUMAN
θ value	5.44631e-05 (rank : 281)	NC score	0.518614 (rank : 211)
Query Neighborhood Hits	480	Target Neighborhood Hits	688	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KLHL6_MOUSE
θ value	5.44631e-05 (rank : 282)	NC score	0.234566 (rank : 320)
Query Neighborhood Hits	480	Target Neighborhood Hits	186	Shared Neighborhood Hits	99
SwissProt Accessions	Q6V595	Gene names	Klhl6
Domain Architecture	No domain graphic available
Description	Kelch-like protein 6.

MTPN_HUMAN
θ value	5.44631e-05 (rank : 283)	NC score	0.753200 (rank : 108)
Query Neighborhood Hits	480	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

RCBT2_HUMAN
θ value	5.44631e-05 (rank : 284)	NC score	0.161445 (rank : 421)
Query Neighborhood Hits	480	Target Neighborhood Hits	158	Shared Neighborhood Hits	81
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

RFXK_MOUSE
θ value	5.44631e-05 (rank : 285)	NC score	0.734674 (rank : 126)
Query Neighborhood Hits	480	Target Neighborhood Hits	273	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB12_MOUSE
θ value	7.1131e-05 (rank : 286)	NC score	0.724713 (rank : 130)
Query Neighborhood Hits	480	Target Neighborhood Hits	261	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

RCBT2_MOUSE
θ value	7.1131e-05 (rank : 287)	NC score	0.163983 (rank : 419)
Query Neighborhood Hits	480	Target Neighborhood Hits	156	Shared Neighborhood Hits	83
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

ZBT40_HUMAN
θ value	7.1131e-05 (rank : 288)	NC score	0.020269 (rank : 539)
Query Neighborhood Hits	480	Target Neighborhood Hits	949	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ASPP2_HUMAN
θ value	9.29e-05 (rank : 289)	NC score	0.521359 (rank : 210)
Query Neighborhood Hits	480	Target Neighborhood Hits	1156	Shared Neighborhood Hits	286
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MTPN_MOUSE
θ value	9.29e-05 (rank : 290)	NC score	0.757522 (rank : 98)
Query Neighborhood Hits	480	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

TDPZ5_MOUSE
θ value	9.29e-05 (rank : 291)	NC score	0.226823 (rank : 345)
Query Neighborhood Hits	480	Target Neighborhood Hits	160	Shared Neighborhood Hits	98
SwissProt Accessions	Q6YCH1	Gene names	Tdpoz5
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 5.

ANS4B_HUMAN
θ value	0.000121331 (rank : 292)	NC score	0.694154 (rank : 147)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

HECD1_HUMAN
θ value	0.000121331 (rank : 293)	NC score	0.550306 (rank : 201)
Query Neighborhood Hits	480	Target Neighborhood Hits	371	Shared Neighborhood Hits	273
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

TEX14_HUMAN
θ value	0.000121331 (rank : 294)	NC score	0.366219 (rank : 262)
Query Neighborhood Hits	480	Target Neighborhood Hits	1103	Shared Neighborhood Hits	247
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANRA2_HUMAN
θ value	0.00020696 (rank : 295)	NC score	0.741310 (rank : 121)
Query Neighborhood Hits	480	Target Neighborhood Hits	288	Shared Neighborhood Hits	277
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
θ value	0.00020696 (rank : 296)	NC score	0.740569 (rank : 124)
Query Neighborhood Hits	480	Target Neighborhood Hits	287	Shared Neighborhood Hits	277
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

IPP_MOUSE
θ value	0.00020696 (rank : 297)	NC score	0.224915 (rank : 350)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	104
SwissProt Accessions	P28575	Gene names	Ipp, Mipp
Domain Architecture
Description	Actin-binding protein IPP (MIPP protein) (Murine IAP-promoted placenta-expressed protein).

USH1G_HUMAN
θ value	0.00020696 (rank : 298)	NC score	0.689531 (rank : 153)
Query Neighborhood Hits	480	Target Neighborhood Hits	267	Shared Neighborhood Hits	260
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	0.00020696 (rank : 299)	NC score	0.689730 (rank : 152)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ZFY19_HUMAN
θ value	0.00020696 (rank : 300)	NC score	0.205001 (rank : 382)
Query Neighborhood Hits	480	Target Neighborhood Hits	206	Shared Neighborhood Hits	53
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

AN13C_HUMAN
θ value	0.000270298 (rank : 301)	NC score	0.495782 (rank : 221)
Query Neighborhood Hits	480	Target Neighborhood Hits	241	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ASZ1_HUMAN
θ value	0.000270298 (rank : 302)	NC score	0.750862 (rank : 110)
Query Neighborhood Hits	480	Target Neighborhood Hits	341	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

GIT2_MOUSE
θ value	0.000270298 (rank : 303)	NC score	0.472692 (rank : 232)
Query Neighborhood Hits	480	Target Neighborhood Hits	323	Shared Neighborhood Hits	252
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

KLH21_HUMAN
θ value	0.000270298 (rank : 304)	NC score	0.227279 (rank : 342)
Query Neighborhood Hits	480	Target Neighborhood Hits	173	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UJP4, O75057	Gene names	KLHL21, KIAA0469
Domain Architecture
Description	Kelch-like protein 21.

KLH22_HUMAN
θ value	0.000270298 (rank : 305)	NC score	0.217061 (rank : 359)
Query Neighborhood Hits	480	Target Neighborhood Hits	198	Shared Neighborhood Hits	104
SwissProt Accessions	Q53GT1, Q96B68, Q96KC6	Gene names	KLHL22
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

RBNS5_HUMAN
θ value	0.000270298 (rank : 306)	NC score	0.194927 (rank : 386)
Query Neighborhood Hits	480	Target Neighborhood Hits	242	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	0.000270298 (rank : 307)	NC score	0.192995 (rank : 389)
Query Neighborhood Hits	480	Target Neighborhood Hits	266	Shared Neighborhood Hits	52
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

KLHL6_HUMAN
θ value	0.00035302 (rank : 308)	NC score	0.233724 (rank : 321)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WZ60, Q8N5I1, Q8N892	Gene names	KLHL6
Domain Architecture
Description	Kelch-like protein 6.

TRPV1_HUMAN
θ value	0.00035302 (rank : 309)	NC score	0.272069 (rank : 292)
Query Neighborhood Hits	480	Target Neighborhood Hits	184	Shared Neighborhood Hits	155
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

ASB12_HUMAN
θ value	0.000461057 (rank : 310)	NC score	0.726449 (rank : 128)
Query Neighborhood Hits	480	Target Neighborhood Hits	263	Shared Neighborhood Hits	260
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

FGD3_HUMAN
θ value	0.000461057 (rank : 311)	NC score	0.161248 (rank : 422)
Query Neighborhood Hits	480	Target Neighborhood Hits	249	Shared Neighborhood Hits	58
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

AN13C_MOUSE
θ value	0.000602161 (rank : 312)	NC score	0.484996 (rank : 228)
Query Neighborhood Hits	480	Target Neighborhood Hits	242	Shared Neighborhood Hits	234
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANS4B_MOUSE
θ value	0.000602161 (rank : 313)	NC score	0.683530 (rank : 158)
Query Neighborhood Hits	480	Target Neighborhood Hits	294	Shared Neighborhood Hits	254
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

CENG1_HUMAN
θ value	0.000602161 (rank : 314)	NC score	0.341136 (rank : 269)
Query Neighborhood Hits	480	Target Neighborhood Hits	544	Shared Neighborhood Hits	242
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

OSTF1_HUMAN
θ value	0.000602161 (rank : 315)	NC score	0.568176 (rank : 197)
Query Neighborhood Hits	480	Target Neighborhood Hits	466	Shared Neighborhood Hits	252
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

TEX14_MOUSE
θ value	0.000602161 (rank : 316)	NC score	0.366102 (rank : 263)
Query Neighborhood Hits	480	Target Neighborhood Hits	1333	Shared Neighborhood Hits	269
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ZFY19_MOUSE
θ value	0.000602161 (rank : 317)	NC score	0.206564 (rank : 379)
Query Neighborhood Hits	480	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY27_HUMAN
θ value	0.000602161 (rank : 318)	NC score	0.174759 (rank : 410)
Query Neighborhood Hits	480	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

CENB1_HUMAN
θ value	0.000786445 (rank : 319)	NC score	0.507580 (rank : 217)
Query Neighborhood Hits	480	Target Neighborhood Hits	383	Shared Neighborhood Hits	259
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

KLH11_HUMAN
θ value	0.000786445 (rank : 320)	NC score	0.225468 (rank : 348)
Query Neighborhood Hits	480	Target Neighborhood Hits	183	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NVR0	Gene names	KLHL11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

KLH23_MOUSE
θ value	0.000786445 (rank : 321)	NC score	0.227233 (rank : 343)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	101
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

ZFY27_MOUSE
θ value	0.000786445 (rank : 322)	NC score	0.174003 (rank : 412)
Query Neighborhood Hits	480	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

AN13B_HUMAN
θ value	0.00102713 (rank : 323)	NC score	0.492961 (rank : 225)
Query Neighborhood Hits	480	Target Neighborhood Hits	265	Shared Neighborhood Hits	254
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	0.00102713 (rank : 324)	NC score	0.493473 (rank : 224)
Query Neighborhood Hits	480	Target Neighborhood Hits	276	Shared Neighborhood Hits	254
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ASB6_HUMAN
θ value	0.00102713 (rank : 325)	NC score	0.701417 (rank : 143)
Query Neighborhood Hits	480	Target Neighborhood Hits	256	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

BTBD3_HUMAN
θ value	0.00102713 (rank : 326)	NC score	0.218815 (rank : 356)
Query Neighborhood Hits	480	Target Neighborhood Hits	127	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y2F9	Gene names	BTBD3, KIAA0952
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

BTBD3_MOUSE
θ value	0.00102713 (rank : 327)	NC score	0.217332 (rank : 357)
Query Neighborhood Hits	480	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	P58545	Gene names	Btbd3
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

IASPP_MOUSE
θ value	0.00102713 (rank : 328)	NC score	0.466483 (rank : 233)
Query Neighborhood Hits	480	Target Neighborhood Hits	1024	Shared Neighborhood Hits	261
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KLH11_MOUSE
θ value	0.00102713 (rank : 329)	NC score	0.225200 (rank : 349)
Query Neighborhood Hits	480	Target Neighborhood Hits	177	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CE33, Q3TDZ6, Q91VP6	Gene names	Klhl11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

OSTF1_MOUSE
θ value	0.00102713 (rank : 330)	NC score	0.581359 (rank : 195)
Query Neighborhood Hits	480	Target Neighborhood Hits	467	Shared Neighborhood Hits	254
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

TDPZ2_MOUSE
θ value	0.00102713 (rank : 331)	NC score	0.227412 (rank : 341)
Query Neighborhood Hits	480	Target Neighborhood Hits	162	Shared Neighborhood Hits	103
SwissProt Accessions	Q717B2	Gene names	Tdpoz2
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 2.

CENG1_MOUSE
θ value	0.00134147 (rank : 332)	NC score	0.342691 (rank : 268)
Query Neighborhood Hits	480	Target Neighborhood Hits	531	Shared Neighborhood Hits	242
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

TDPZ1_MOUSE
θ value	0.00134147 (rank : 333)	NC score	0.227519 (rank : 339)
Query Neighborhood Hits	480	Target Neighborhood Hits	164	Shared Neighborhood Hits	100
SwissProt Accessions	Q717B3, Q71G58, Q8BZV7, Q8VI39	Gene names	Tdpoz1, 2cpoz56, Mapp2, Spopl1
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 1 (MAPP family protein 2).

AN13A_HUMAN
θ value	0.00175202 (rank : 334)	NC score	0.441365 (rank : 243)
Query Neighborhood Hits	480	Target Neighborhood Hits	243	Shared Neighborhood Hits	227
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANR37_HUMAN
θ value	0.00175202 (rank : 335)	NC score	0.670012 (rank : 162)
Query Neighborhood Hits	480	Target Neighborhood Hits	247	Shared Neighborhood Hits	246
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

GAN_HUMAN
θ value	0.00175202 (rank : 336)	NC score	0.226755 (rank : 346)
Query Neighborhood Hits	480	Target Neighborhood Hits	180	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2C0	Gene names	GAN, GAN1, KLHL16
Domain Architecture
Description	Gigaxonin (Kelch-like protein 16).

TRPV3_MOUSE
θ value	0.00175202 (rank : 337)	NC score	0.287391 (rank : 286)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	138
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

ABTB1_MOUSE
θ value	0.00228821 (rank : 338)	NC score	0.434413 (rank : 246)
Query Neighborhood Hits	480	Target Neighborhood Hits	349	Shared Neighborhood Hits	270
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ASB1_MOUSE
θ value	0.00228821 (rank : 339)	NC score	0.717465 (rank : 136)
Query Neighborhood Hits	480	Target Neighborhood Hits	292	Shared Neighborhood Hits	276
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

GIT2_HUMAN
θ value	0.00228821 (rank : 340)	NC score	0.439356 (rank : 245)
Query Neighborhood Hits	480	Target Neighborhood Hits	381	Shared Neighborhood Hits	251
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

ANKY1_HUMAN
θ value	0.00298849 (rank : 341)	NC score	0.537280 (rank : 204)
Query Neighborhood Hits	480	Target Neighborhood Hits	248	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

KLH23_HUMAN
θ value	0.00298849 (rank : 342)	NC score	0.229268 (rank : 330)
Query Neighborhood Hits	480	Target Neighborhood Hits	198	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

ANKY2_HUMAN
θ value	0.00390308 (rank : 343)	NC score	0.669906 (rank : 163)
Query Neighborhood Hits	480	Target Neighborhood Hits	306	Shared Neighborhood Hits	266
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR41_HUMAN
θ value	0.00390308 (rank : 344)	NC score	0.686458 (rank : 156)
Query Neighborhood Hits	480	Target Neighborhood Hits	332	Shared Neighborhood Hits	255
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ASB1_HUMAN
θ value	0.00390308 (rank : 345)	NC score	0.718581 (rank : 135)
Query Neighborhood Hits	480	Target Neighborhood Hits	291	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CENG2_HUMAN
θ value	0.00390308 (rank : 346)	NC score	0.335952 (rank : 271)
Query Neighborhood Hits	480	Target Neighborhood Hits	471	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

GIT1_HUMAN
θ value	0.00390308 (rank : 347)	NC score	0.457683 (rank : 238)
Query Neighborhood Hits	480	Target Neighborhood Hits	336	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.00390308 (rank : 348)	NC score	0.459197 (rank : 237)
Query Neighborhood Hits	480	Target Neighborhood Hits	341	Shared Neighborhood Hits	250
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

TDPZ3_MOUSE
θ value	0.00390308 (rank : 349)	NC score	0.226160 (rank : 347)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	102
SwissProt Accessions	Q717B4	Gene names	Tdpoz3
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 3.

ANR45_MOUSE
θ value	0.00509761 (rank : 350)	NC score	0.568424 (rank : 196)
Query Neighborhood Hits	480	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

CENB5_HUMAN
θ value	0.00509761 (rank : 351)	NC score	0.508417 (rank : 215)
Query Neighborhood Hits	480	Target Neighborhood Hits	395	Shared Neighborhood Hits	270
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CLPB_MOUSE
θ value	0.00509761 (rank : 352)	NC score	0.624696 (rank : 187)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	249
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

FGD3_MOUSE
θ value	0.00509761 (rank : 353)	NC score	0.144201 (rank : 431)
Query Neighborhood Hits	480	Target Neighborhood Hits	257	Shared Neighborhood Hits	57
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

KLH22_MOUSE
θ value	0.00509761 (rank : 354)	NC score	0.214558 (rank : 363)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	105
SwissProt Accessions	Q99JN2, Q8BT13	Gene names	Klhl22, Kelchl
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

KLH26_HUMAN
θ value	0.00509761 (rank : 355)	NC score	0.207151 (rank : 377)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	101
SwissProt Accessions	Q53HC5, Q8TAP0, Q9NUX3	Gene names	KLHL26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

CENG3_HUMAN
θ value	0.00665767 (rank : 356)	NC score	0.311072 (rank : 278)
Query Neighborhood Hits	480	Target Neighborhood Hits	455	Shared Neighborhood Hits	229
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.00665767 (rank : 357)	NC score	0.311296 (rank : 277)
Query Neighborhood Hits	480	Target Neighborhood Hits	467	Shared Neighborhood Hits	229
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

BKLH5_HUMAN
θ value	0.00869519 (rank : 358)	NC score	0.208500 (rank : 374)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	Q96NJ5, Q96PY7	Gene names	BKLHD5, KIAA1900
Domain Architecture
Description	BTB and kelch domain-containing protein 5.

DDFL1_MOUSE
θ value	0.00869519 (rank : 359)	NC score	0.420851 (rank : 247)
Query Neighborhood Hits	480	Target Neighborhood Hits	324	Shared Neighborhood Hits	252
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CENG2_MOUSE
θ value	0.0113563 (rank : 360)	NC score	0.332119 (rank : 273)
Query Neighborhood Hits	480	Target Neighborhood Hits	463	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DGKZ_HUMAN
θ value	0.0113563 (rank : 361)	NC score	0.349621 (rank : 265)
Query Neighborhood Hits	480	Target Neighborhood Hits	551	Shared Neighborhood Hits	222
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

KBTB9_MOUSE
θ value	0.0113563 (rank : 362)	NC score	0.215534 (rank : 362)
Query Neighborhood Hits	480	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KLH10_HUMAN
θ value	0.0113563 (rank : 363)	NC score	0.223172 (rank : 353)
Query Neighborhood Hits	480	Target Neighborhood Hits	194	Shared Neighborhood Hits	104
SwissProt Accessions	Q6JEL2, Q6NW28, Q96MC0	Gene names	KLHL10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KLH26_MOUSE
θ value	0.0113563 (rank : 364)	NC score	0.207850 (rank : 375)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BGY4, Q8CIG6, Q8R153	Gene names	Klhl26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

ANR33_MOUSE
θ value	0.0148317 (rank : 365)	NC score	0.648654 (rank : 176)
Query Neighborhood Hits	480	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

GOGA4_HUMAN
θ value	0.0148317 (rank : 366)	NC score	0.054033 (rank : 492)
Query Neighborhood Hits	480	Target Neighborhood Hits	2034	Shared Neighborhood Hits	66
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

ZBT16_HUMAN
θ value	0.0148317 (rank : 367)	NC score	0.020041 (rank : 540)
Query Neighborhood Hits	480	Target Neighborhood Hits	1010	Shared Neighborhood Hits	99
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

AN13A_MOUSE
θ value	0.0252991 (rank : 368)	NC score	0.419249 (rank : 248)
Query Neighborhood Hits	480	Target Neighborhood Hits	226	Shared Neighborhood Hits	216
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CALI_HUMAN
θ value	0.0252991 (rank : 369)	NC score	0.216509 (rank : 360)
Query Neighborhood Hits	480	Target Neighborhood Hits	183	Shared Neighborhood Hits	98
SwissProt Accessions	Q13939, Q9BXG7	Gene names	CCIN
Domain Architecture
Description	Calicin.

GMCL1_HUMAN
θ value	0.0252991 (rank : 370)	NC score	0.147345 (rank : 430)
Query Neighborhood Hits	480	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	Q96IK5, Q9H826, Q9H8V7, Q9H927	Gene names	GMCL1, GCL
Domain Architecture
Description	Germ cell-less protein-like 1.

KBTBB_HUMAN
θ value	0.0252991 (rank : 371)	NC score	0.184022 (rank : 404)
Query Neighborhood Hits	480	Target Neighborhood Hits	195	Shared Neighborhood Hits	86
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

KBTBB_MOUSE
θ value	0.0252991 (rank : 372)	NC score	0.187890 (rank : 397)
Query Neighborhood Hits	480	Target Neighborhood Hits	184	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BNW9	Gene names	Kbtbd11, Kiaa0711
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 11.

ANR45_HUMAN
θ value	0.0330416 (rank : 373)	NC score	0.530864 (rank : 207)
Query Neighborhood Hits	480	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

RHBT1_HUMAN
θ value	0.0330416 (rank : 374)	NC score	0.068399 (rank : 470)
Query Neighborhood Hits	480	Target Neighborhood Hits	262	Shared Neighborhood Hits	79
SwissProt Accessions	O94844	Gene names	RHOBTB1, KIAA0740
Domain Architecture
Description	Rho-related BTB domain-containing protein 1.

ANKY2_MOUSE
θ value	0.0431538 (rank : 375)	NC score	0.645733 (rank : 180)
Query Neighborhood Hits	480	Target Neighborhood Hits	316	Shared Neighborhood Hits	266
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

KLH18_HUMAN
θ value	0.0431538 (rank : 376)	NC score	0.210174 (rank : 372)
Query Neighborhood Hits	480	Target Neighborhood Hits	143	Shared Neighborhood Hits	75
SwissProt Accessions	O94889, Q8N125	Gene names	KLHL18, KIAA0795
Domain Architecture
Description	Kelch-like protein 18.

CLR59_HUMAN
θ value	0.0563607 (rank : 377)	NC score	0.285045 (rank : 287)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	141
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

DDFL1_HUMAN
θ value	0.0563607 (rank : 378)	NC score	0.337499 (rank : 270)
Query Neighborhood Hits	480	Target Neighborhood Hits	353	Shared Neighborhood Hits	229
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

KBTB9_HUMAN
θ value	0.0563607 (rank : 379)	NC score	0.214295 (rank : 364)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	100
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

GMCL1_MOUSE
θ value	0.0736092 (rank : 380)	NC score	0.147649 (rank : 429)
Query Neighborhood Hits	480	Target Neighborhood Hits	87	Shared Neighborhood Hits	65
SwissProt Accessions	Q920G9, Q9DBW5, Q9QUP6	Gene names	Gmcl1, Gcl, Gcl1
Domain Architecture
Description	Germ cell-less protein-like 1 (mGcl-1) (DP-interacting protein) (DIP).

KBTB6_HUMAN
θ value	0.0736092 (rank : 381)	NC score	0.217246 (rank : 358)
Query Neighborhood Hits	480	Target Neighborhood Hits	175	Shared Neighborhood Hits	101
SwissProt Accessions	Q86V97, Q8N8L0, Q8NDM5, Q96MP6	Gene names	KBTBD6
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 6.

CT012_HUMAN
θ value	0.0961366 (rank : 382)	NC score	0.381672 (rank : 259)
Query Neighborhood Hits	480	Target Neighborhood Hits	205	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DGKZ_MOUSE
θ value	0.0961366 (rank : 383)	NC score	0.331333 (rank : 274)
Query Neighborhood Hits	480	Target Neighborhood Hits	542	Shared Neighborhood Hits	208
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

IKBL_HUMAN
θ value	0.0961366 (rank : 384)	NC score	0.334251 (rank : 272)
Query Neighborhood Hits	480	Target Neighborhood Hits	168	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	0.0961366 (rank : 385)	NC score	0.326389 (rank : 275)
Query Neighborhood Hits	480	Target Neighborhood Hits	196	Shared Neighborhood Hits	139
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ANR33_HUMAN
θ value	0.163984 (rank : 386)	NC score	0.628709 (rank : 185)
Query Neighborhood Hits	480	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR43_HUMAN
θ value	0.163984 (rank : 387)	NC score	0.558323 (rank : 199)
Query Neighborhood Hits	480	Target Neighborhood Hits	209	Shared Neighborhood Hits	201
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

NUD12_HUMAN
θ value	0.163984 (rank : 388)	NC score	0.478851 (rank : 230)
Query Neighborhood Hits	480	Target Neighborhood Hits	222	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPV2_HUMAN
θ value	0.163984 (rank : 389)	NC score	0.250869 (rank : 309)
Query Neighborhood Hits	480	Target Neighborhood Hits	130	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ANR43_MOUSE
θ value	0.21417 (rank : 390)	NC score	0.547169 (rank : 202)
Query Neighborhood Hits	480	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

BAT4_MOUSE
θ value	0.21417 (rank : 391)	NC score	0.259452 (rank : 295)
Query Neighborhood Hits	480	Target Neighborhood Hits	171	Shared Neighborhood Hits	119
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CD2A1_MOUSE
θ value	0.21417 (rank : 392)	NC score	0.624787 (rank : 186)
Query Neighborhood Hits	480	Target Neighborhood Hits	206	Shared Neighborhood Hits	202
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CN037_MOUSE
θ value	0.21417 (rank : 393)	NC score	0.032453 (rank : 526)
Query Neighborhood Hits	480	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

MIPO1_MOUSE
θ value	0.21417 (rank : 394)	NC score	0.058934 (rank : 479)
Query Neighborhood Hits	480	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D9F8	Gene names	Mipol1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein homolog.

SMC4_HUMAN
θ value	0.21417 (rank : 395)	NC score	0.047807 (rank : 515)
Query Neighborhood Hits	480	Target Neighborhood Hits	937	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

DDEF2_HUMAN
θ value	0.279714 (rank : 396)	NC score	0.351417 (rank : 264)
Query Neighborhood Hits	480	Target Neighborhood Hits	599	Shared Neighborhood Hits	235
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.279714 (rank : 397)	NC score	0.349362 (rank : 267)
Query Neighborhood Hits	480	Target Neighborhood Hits	625	Shared Neighborhood Hits	239
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

KBTB7_HUMAN
θ value	0.279714 (rank : 398)	NC score	0.215663 (rank : 361)
Query Neighborhood Hits	480	Target Neighborhood Hits	183	Shared Neighborhood Hits	102
SwissProt Accessions	Q8WVZ9, Q8NB99, Q9H0I6	Gene names	KBTBD7
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 7.

ANR40_MOUSE
θ value	0.365318 (rank : 399)	NC score	0.516135 (rank : 214)
Query Neighborhood Hits	480	Target Neighborhood Hits	228	Shared Neighborhood Hits	203
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

GLSL_HUMAN
θ value	0.365318 (rank : 400)	NC score	0.454627 (rank : 239)
Query Neighborhood Hits	480	Target Neighborhood Hits	211	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GMCLL_HUMAN
θ value	0.365318 (rank : 401)	NC score	0.138778 (rank : 435)
Query Neighborhood Hits	480	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NEA9, Q8TC88, Q8TC89	Gene names	GMCL1L, GCL
Domain Architecture
Description	Germ cell-less protein-like 1-like.

ANKZ1_HUMAN
θ value	0.47712 (rank : 402)	NC score	0.298576 (rank : 283)
Query Neighborhood Hits	480	Target Neighborhood Hits	236	Shared Neighborhood Hits	160
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANR40_HUMAN
θ value	0.47712 (rank : 403)	NC score	0.518282 (rank : 213)
Query Neighborhood Hits	480	Target Neighborhood Hits	224	Shared Neighborhood Hits	199
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CDN2B_MOUSE
θ value	0.47712 (rank : 404)	NC score	0.585931 (rank : 193)
Query Neighborhood Hits	480	Target Neighborhood Hits	201	Shared Neighborhood Hits	195
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

RSNL2_HUMAN
θ value	0.47712 (rank : 405)	NC score	0.226831 (rank : 344)
Query Neighborhood Hits	480	Target Neighborhood Hits	136	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TDRKH_HUMAN
θ value	0.62314 (rank : 406)	NC score	0.010918 (rank : 545)
Query Neighborhood Hits	480	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TRPC6_HUMAN
θ value	0.62314 (rank : 407)	NC score	0.112594 (rank : 449)
Query Neighborhood Hits	480	Target Neighborhood Hits	171	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

CT012_MOUSE
θ value	0.813845 (rank : 408)	NC score	0.410261 (rank : 252)
Query Neighborhood Hits	480	Target Neighborhood Hits	229	Shared Neighborhood Hits	180
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

DGKI_HUMAN
θ value	0.813845 (rank : 409)	NC score	0.315935 (rank : 276)
Query Neighborhood Hits	480	Target Neighborhood Hits	609	Shared Neighborhood Hits	222
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

NUD12_MOUSE
θ value	0.813845 (rank : 410)	NC score	0.502167 (rank : 218)
Query Neighborhood Hits	480	Target Neighborhood Hits	243	Shared Neighborhood Hits	222
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

RC3H1_HUMAN
θ value	0.813845 (rank : 411)	NC score	0.018178 (rank : 544)
Query Neighborhood Hits	480	Target Neighborhood Hits	433	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	0.813845 (rank : 412)	NC score	0.019013 (rank : 542)
Query Neighborhood Hits	480	Target Neighborhood Hits	244	Shared Neighborhood Hits	13
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

ANKZ1_MOUSE
θ value	1.06291 (rank : 413)	NC score	0.306217 (rank : 279)
Query Neighborhood Hits	480	Target Neighborhood Hits	208	Shared Neighborhood Hits	152
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

GLSL_MOUSE
θ value	1.06291 (rank : 414)	NC score	0.443747 (rank : 242)
Query Neighborhood Hits	480	Target Neighborhood Hits	212	Shared Neighborhood Hits	202
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

KHL15_HUMAN
θ value	1.06291 (rank : 415)	NC score	0.201559 (rank : 383)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	102
SwissProt Accessions	Q96M94, Q32MN3, Q8NDA3, Q96BM6, Q9C0I6	Gene names	KLHL15, KIAA1677
Domain Architecture	No domain graphic available
Description	Kelch-like protein 15.

RFFL_MOUSE
θ value	1.06291 (rank : 416)	NC score	0.078358 (rank : 458)
Query Neighborhood Hits	480	Target Neighborhood Hits	145	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

ZBT25_HUMAN
θ value	1.06291 (rank : 417)	NC score	0.075035 (rank : 462)
Query Neighborhood Hits	480	Target Neighborhood Hits	644	Shared Neighborhood Hits	83
SwissProt Accessions	P24278, Q8IYH9	Gene names	ZBTB25, KUP, ZNF46
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP).

ZBTB5_HUMAN
θ value	1.06291 (rank : 418)	NC score	0.065172 (rank : 474)
Query Neighborhood Hits	480	Target Neighborhood Hits	811	Shared Neighborhood Hits	100
SwissProt Accessions	O15062	Gene names	ZBTB5, KIAA0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5.

ZBTB5_MOUSE
θ value	1.06291 (rank : 419)	NC score	0.065300 (rank : 472)
Query Neighborhood Hits	480	Target Neighborhood Hits	801	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).

ZF161_HUMAN
θ value	1.06291 (rank : 420)	NC score	0.027095 (rank : 529)
Query Neighborhood Hits	480	Target Neighborhood Hits	822	Shared Neighborhood Hits	97
SwissProt Accessions	O43829, O00403	Gene names	ZFP161, ZBTB14
Domain Architecture
Description	Zinc finger protein 161 homolog (Zfp-161) (Zinc finger protein 5) (hZF5) (Zinc finger and BTB domain-containing protein 14).

CD2A1_HUMAN
θ value	1.38821 (rank : 421)	NC score	0.551619 (rank : 200)
Query Neighborhood Hits	480	Target Neighborhood Hits	196	Shared Neighborhood Hits	190
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CLPB_HUMAN
θ value	1.38821 (rank : 422)	NC score	0.530883 (rank : 206)
Query Neighborhood Hits	480	Target Neighborhood Hits	265	Shared Neighborhood Hits	238
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ZBT17_HUMAN
θ value	1.38821 (rank : 423)	NC score	0.018327 (rank : 543)
Query Neighborhood Hits	480	Target Neighborhood Hits	925	Shared Neighborhood Hits	106
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

ZBT38_HUMAN
θ value	1.38821 (rank : 424)	NC score	0.020686 (rank : 538)
Query Neighborhood Hits	480	Target Neighborhood Hits	885	Shared Neighborhood Hits	101
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

ZF161_MOUSE
θ value	1.38821 (rank : 425)	NC score	0.026961 (rank : 530)
Query Neighborhood Hits	480	Target Neighborhood Hits	821	Shared Neighborhood Hits	97
SwissProt Accessions	Q08376	Gene names	Zfp161, Zfp-5, Zfp5
Domain Architecture
Description	Zinc finger protein 161 (Zfp-161) (Zinc finger protein 5) (ZF5).

ZN318_HUMAN
θ value	1.38821 (rank : 426)	NC score	0.023613 (rank : 534)
Query Neighborhood Hits	480	Target Neighborhood Hits	497	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

CDN2B_HUMAN
θ value	1.81305 (rank : 427)	NC score	0.541399 (rank : 203)
Query Neighborhood Hits	480	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

GCC1_HUMAN
θ value	1.81305 (rank : 428)	NC score	0.042312 (rank : 518)
Query Neighborhood Hits	480	Target Neighborhood Hits	887	Shared Neighborhood Hits	40
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

NOL1_HUMAN
θ value	1.81305 (rank : 429)	NC score	0.026145 (rank : 533)
Query Neighborhood Hits	480	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	P46087	Gene names	NOL1
Domain Architecture
Description	Proliferating-cell nucleolar antigen p120 (Proliferation-associated nucleolar protein p120).

TRPC3_HUMAN
θ value	1.81305 (rank : 430)	NC score	0.091506 (rank : 452)
Query Neighborhood Hits	480	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC5_HUMAN
θ value	1.81305 (rank : 431)	NC score	0.076380 (rank : 461)
Query Neighborhood Hits	480	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	1.81305 (rank : 432)	NC score	0.077715 (rank : 459)
Query Neighborhood Hits	480	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC6_MOUSE
θ value	1.81305 (rank : 433)	NC score	0.088173 (rank : 453)
Query Neighborhood Hits	480	Target Neighborhood Hits	171	Shared Neighborhood Hits	97
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPV4_HUMAN
θ value	1.81305 (rank : 434)	NC score	0.166839 (rank : 417)
Query Neighborhood Hits	480	Target Neighborhood Hits	150	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	1.81305 (rank : 435)	NC score	0.156590 (rank : 425)
Query Neighborhood Hits	480	Target Neighborhood Hits	117	Shared Neighborhood Hits	85
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ZBT37_HUMAN
θ value	1.81305 (rank : 436)	NC score	0.045147 (rank : 516)
Query Neighborhood Hits	480	Target Neighborhood Hits	815	Shared Neighborhood Hits	93
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

ZBT45_HUMAN
θ value	1.81305 (rank : 437)	NC score	0.021142 (rank : 537)
Query Neighborhood Hits	480	Target Neighborhood Hits	901	Shared Neighborhood Hits	85
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

TRPC3_MOUSE
θ value	2.36792 (rank : 438)	NC score	0.084062 (rank : 455)
Query Neighborhood Hits	480	Target Neighborhood Hits	131	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

ZBT34_HUMAN
θ value	2.36792 (rank : 439)	NC score	0.043201 (rank : 517)
Query Neighborhood Hits	480	Target Neighborhood Hits	799	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NCN2	Gene names	ZBTB34, KIAA1993
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 34.

ZBTB2_HUMAN
θ value	2.36792 (rank : 440)	NC score	0.027697 (rank : 527)
Query Neighborhood Hits	480	Target Neighborhood Hits	752	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N680, Q5SZ81, Q9P245	Gene names	ZBTB2, KIAA1483, ZNF437
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 2.

ABTB1_HUMAN
θ value	3.0926 (rank : 441)	NC score	0.391752 (rank : 258)
Query Neighborhood Hits	480	Target Neighborhood Hits	325	Shared Neighborhood Hits	252
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

TRPV2_MOUSE
θ value	3.0926 (rank : 442)	NC score	0.201276 (rank : 384)
Query Neighborhood Hits	480	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

ZBTB6_HUMAN
θ value	3.0926 (rank : 443)	NC score	0.026676 (rank : 531)
Query Neighborhood Hits	480	Target Neighborhood Hits	805	Shared Neighborhood Hits	84
SwissProt Accessions	Q15916	Gene names	ZBTB6, ZID, ZNF482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain).

ZBTB6_MOUSE
θ value	3.0926 (rank : 444)	NC score	0.026320 (rank : 532)
Query Neighborhood Hits	480	Target Neighborhood Hits	793	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K088, Q8BLM4	Gene names	Zbtb6, Zfp482, Znf482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482).

ZN131_HUMAN
θ value	3.0926 (rank : 445)	NC score	0.032550 (rank : 525)
Query Neighborhood Hits	480	Target Neighborhood Hits	833	Shared Neighborhood Hits	97
SwissProt Accessions	P52739, Q6PIF0	Gene names	ZNF131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

ZN131_MOUSE
θ value	3.0926 (rank : 446)	NC score	0.032768 (rank : 524)
Query Neighborhood Hits	480	Target Neighborhood Hits	833	Shared Neighborhood Hits	99
SwissProt Accessions	Q8K3J5, Q3UYZ4, Q80UU7, Q8C8D0, Q9D042	Gene names	Znf131, Zfp131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

ANKR9_HUMAN
θ value	4.03905 (rank : 447)	NC score	0.228286 (rank : 336)
Query Neighborhood Hits	480	Target Neighborhood Hits	99	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	4.03905 (rank : 448)	NC score	0.274363 (rank : 290)
Query Neighborhood Hits	480	Target Neighborhood Hits	120	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

RFFL_HUMAN
θ value	4.03905 (rank : 449)	NC score	0.072833 (rank : 466)
Query Neighborhood Hits	480	Target Neighborhood Hits	175	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

TRPC4_HUMAN
θ value	4.03905 (rank : 450)	NC score	0.074033 (rank : 465)
Query Neighborhood Hits	480	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	4.03905 (rank : 451)	NC score	0.074166 (rank : 463)
Query Neighborhood Hits	480	Target Neighborhood Hits	141	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

ZN295_HUMAN
θ value	4.03905 (rank : 452)	NC score	0.053422 (rank : 497)
Query Neighborhood Hits	480	Target Neighborhood Hits	847	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

TRPC7_HUMAN
θ value	5.27518 (rank : 453)	NC score	0.079777 (rank : 457)
Query Neighborhood Hits	480	Target Neighborhood Hits	123	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	5.27518 (rank : 454)	NC score	0.079887 (rank : 456)
Query Neighborhood Hits	480	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRRAP_HUMAN
θ value	5.27518 (rank : 455)	NC score	0.008797 (rank : 547)
Query Neighborhood Hits	480	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

TRRAP_MOUSE
θ value	5.27518 (rank : 456)	NC score	0.009148 (rank : 546)
Query Neighborhood Hits	480	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

ZBT12_HUMAN
θ value	5.27518 (rank : 457)	NC score	0.027309 (rank : 528)
Query Neighborhood Hits	480	Target Neighborhood Hits	784	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y330, Q5JQ98	Gene names	ZBTB12, C6orf46, G10, NG35
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 12 (Protein G10).

ANKF1_HUMAN
θ value	6.88961 (rank : 458)	NC score	0.138910 (rank : 434)
Query Neighborhood Hits	480	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

BTBD8_HUMAN
θ value	6.88961 (rank : 459)	NC score	0.188460 (rank : 395)
Query Neighborhood Hits	480	Target Neighborhood Hits	146	Shared Neighborhood Hits	88
SwissProt Accessions	Q5XKL5, Q6V9S5	Gene names	BTBD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 8.

COE3_MOUSE
θ value	6.88961 (rank : 460)	NC score	0.006871 (rank : 548)
Query Neighborhood Hits	480	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

DDEF1_MOUSE
θ value	6.88961 (rank : 461)	NC score	0.265994 (rank : 294)
Query Neighborhood Hits	480	Target Neighborhood Hits	592	Shared Neighborhood Hits	199
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

GLSK_HUMAN
θ value	6.88961 (rank : 462)	NC score	0.410311 (rank : 251)
Query Neighborhood Hits	480	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

NELL1_HUMAN
θ value	6.88961 (rank : 463)	NC score	0.035107 (rank : 521)
Query Neighborhood Hits	480	Target Neighborhood Hits	451	Shared Neighborhood Hits	10
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

PDZD6_HUMAN
θ value	6.88961 (rank : 464)	NC score	0.005893 (rank : 549)
Query Neighborhood Hits	480	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PGFRA_HUMAN
θ value	6.88961 (rank : 465)	NC score	0.002795 (rank : 552)
Query Neighborhood Hits	480	Target Neighborhood Hits	980	Shared Neighborhood Hits	17
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PK3CG_HUMAN
θ value	6.88961 (rank : 466)	NC score	0.002962 (rank : 550)
Query Neighborhood Hits	480	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
θ value	6.88961 (rank : 467)	NC score	0.002953 (rank : 551)
Query Neighborhood Hits	480	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

RNF34_HUMAN
θ value	6.88961 (rank : 468)	NC score	0.072158 (rank : 467)
Query Neighborhood Hits	480	Target Neighborhood Hits	153	Shared Neighborhood Hits	37
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

TRI56_HUMAN
θ value	6.88961 (rank : 469)	NC score	-0.001364 (rank : 554)
Query Neighborhood Hits	480	Target Neighborhood Hits	339	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

Z297B_MOUSE
θ value	6.88961 (rank : 470)	NC score	0.036326 (rank : 520)
Query Neighborhood Hits	480	Target Neighborhood Hits	806	Shared Neighborhood Hits	93
SwissProt Accessions	Q9DAI4	Gene names	Znf297b, Kiaa0414, Zfp297b
Domain Architecture
Description	Zinc finger protein 297B.

GOGA4_MOUSE
θ value	8.99809 (rank : 471)	NC score	0.047967 (rank : 514)
Query Neighborhood Hits	480	Target Neighborhood Hits	1939	Shared Neighborhood Hits	64
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

KI21A_HUMAN
θ value	8.99809 (rank : 472)	NC score	0.023166 (rank : 536)
Query Neighborhood Hits	480	Target Neighborhood Hits	1543	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KI21A_MOUSE
θ value	8.99809 (rank : 473)	NC score	0.019357 (rank : 541)
Query Neighborhood Hits	480	Target Neighborhood Hits	1317	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MIPO1_HUMAN
θ value	8.99809 (rank : 474)	NC score	0.039631 (rank : 519)
Query Neighborhood Hits	480	Target Neighborhood Hits	486	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MRCKB_MOUSE
θ value	8.99809 (rank : 475)	NC score	0.023465 (rank : 535)
Query Neighborhood Hits	480	Target Neighborhood Hits	2180	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PGFRA_MOUSE
θ value	8.99809 (rank : 476)	NC score	0.002599 (rank : 553)
Query Neighborhood Hits	480	Target Neighborhood Hits	975	Shared Neighborhood Hits	17
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

RNF34_MOUSE
θ value	8.99809 (rank : 477)	NC score	0.074066 (rank : 464)
Query Neighborhood Hits	480	Target Neighborhood Hits	160	Shared Neighborhood Hits	39
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

TRI41_HUMAN
θ value	8.99809 (rank : 478)	NC score	-0.001652 (rank : 555)
Query Neighborhood Hits	480	Target Neighborhood Hits	349	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

ZN238_HUMAN
θ value	8.99809 (rank : 479)	NC score	0.032889 (rank : 523)
Query Neighborhood Hits	480	Target Neighborhood Hits	836	Shared Neighborhood Hits	98
SwissProt Accessions	Q99592, Q13397, Q5VU40, Q8N463	Gene names	ZNF238, RP58, TAZ1, ZBTB18
Domain Architecture
Description	Zinc finger protein 238 (Transcriptional repressor RP58) (58 kDa repressor protein) (Zinc finger protein C2H2-171) (Translin-associated zinc finger protein 1) (TAZ-1) (Zinc finger and BTB domain-containing protein 18).

ZN238_MOUSE
θ value	8.99809 (rank : 480)	NC score	0.033253 (rank : 522)
Query Neighborhood Hits	480	Target Neighborhood Hits	837	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WUK6	Gene names	Znf238, Rp58, Zfp238
Domain Architecture
Description	Zinc finger protein 238 (Zfp-238) (Transcriptional repressor RP58) (58 kDa repressor protein).

ASB14_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.494810 (rank : 222)
Query Neighborhood Hits	480	Target Neighborhood Hits	187	Shared Neighborhood Hits	172
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ATRN_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.053549 (rank : 495)
Query Neighborhood Hits	480	Target Neighborhood Hits	525	Shared Neighborhood Hits	53
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

BACH1_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.118610 (rank : 447)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH1_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.118900 (rank : 446)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

BACH2_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.123480 (rank : 443)
Query Neighborhood Hits	480	Target Neighborhood Hits	234	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH2_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.118002 (rank : 448)
Query Neighborhood Hits	480	Target Neighborhood Hits	248	Shared Neighborhood Hits	93
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BAT4_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.221535 (rank : 354)
Query Neighborhood Hits	480	Target Neighborhood Hits	157	Shared Neighborhood Hits	109
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BTBD6_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.192510 (rank : 391)
Query Neighborhood Hits	480	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	Q96KE9, Q8IVQ7, Q9BR94	Gene names	BTBD6, BDPL
Domain Architecture
Description	BTB/POZ domain-containing protein 6 (Lens BTB domain protein).

BTBD7_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.094900 (rank : 451)
Query Neighborhood Hits	480	Target Neighborhood Hits	176	Shared Neighborhood Hits	79
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

BTBD7_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.100980 (rank : 450)
Query Neighborhood Hits	480	Target Neighborhood Hits	228	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

CCD41_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.050287 (rank : 510)
Query Neighborhood Hits	480	Target Neighborhood Hits	1139	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CI039_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.050092 (rank : 513)
Query Neighborhood Hits	480	Target Neighborhood Hits	1171	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CMTA1_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.165673 (rank : 418)
Query Neighborhood Hits	480	Target Neighborhood Hits	217	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.129320 (rank : 440)
Query Neighborhood Hits	480	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.121594 (rank : 445)
Query Neighborhood Hits	480	Target Neighborhood Hits	216	Shared Neighborhood Hits	74
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CP135_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.050326 (rank : 509)
Query Neighborhood Hits	480	Target Neighborhood Hits	1290	Shared Neighborhood Hits	50
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CRUM2_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.050173 (rank : 512)
Query Neighborhood Hits	480	Target Neighborhood Hits	453	Shared Neighborhood Hits	9
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CU081_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.128056 (rank : 441)
Query Neighborhood Hits	480	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DNER_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.050583 (rank : 508)
Query Neighborhood Hits	480	Target Neighborhood Hits	460	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.051510 (rank : 506)
Query Neighborhood Hits	480	Target Neighborhood Hits	413	Shared Neighborhood Hits	9
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

FADD_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.057441 (rank : 480)
Query Neighborhood Hits	480	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

FADD_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.063773 (rank : 476)
Query Neighborhood Hits	480	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

JAG1_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.051618 (rank : 505)
Query Neighborhood Hits	480	Target Neighborhood Hits	514	Shared Neighborhood Hits	9
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.051260 (rank : 507)
Query Neighborhood Hits	480	Target Neighborhood Hits	518	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.051663 (rank : 503)
Query Neighborhood Hits	480	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.052802 (rank : 500)
Query Neighborhood Hits	480	Target Neighborhood Hits	504	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KEAP1_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.213344 (rank : 368)
Query Neighborhood Hits	480	Target Neighborhood Hits	181	Shared Neighborhood Hits	101
SwissProt Accessions	Q14145, Q6LEP0	Gene names	KEAP1, KIAA0132, KLHL19
Domain Architecture	No domain graphic available
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (Kelch-like protein 19).

KEAP1_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.212751 (rank : 370)
Query Neighborhood Hits	480	Target Neighborhood Hits	182	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z2X8	Gene names	Keap1
Domain Architecture
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2).

KLD7B_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.155389 (rank : 426)
Query Neighborhood Hits	480	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q96G42	Gene names	KLHDC7B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 7B.

KLD8A_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.148717 (rank : 428)
Query Neighborhood Hits	480	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IYD2, Q9NVG5	Gene names	KLHDC8A
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLD8A_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.149267 (rank : 427)
Query Neighborhood Hits	480	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XA8	Gene names	Klhdc8a
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLD8B_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.139924 (rank : 433)
Query Neighborhood Hits	480	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IXV7	Gene names	KLHDC8B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLD8B_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.140585 (rank : 432)
Query Neighborhood Hits	480	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D2D9	Gene names	Klhdc8b
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLDC3_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.077282 (rank : 460)
Query Neighborhood Hits	480	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BQ90	Gene names	KLHDC3, PEAS
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

KLDC3_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.085489 (rank : 454)
Query Neighborhood Hits	480	Target Neighborhood Hits	77	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEM9, Q3TCN9, Q3UR95, Q91XU6, Q99JH9, Q9DBG8	Gene names	Klhdc3, Peas
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

KLDC5_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.162164 (rank : 420)
Query Neighborhood Hits	480	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P2K6, Q2VPK1, Q8N334	Gene names	KLHDC5, KIAA1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

KLDC5_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.159855 (rank : 423)
Query Neighborhood Hits	480	Target Neighborhood Hits	86	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BFQ9, Q6ZPT4	Gene names	Klhdc5, Kiaa1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

KLH10_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.213606 (rank : 367)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D5V2, Q8BVM3, Q9DA07	Gene names	Klhl10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KLH13_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.193379 (rank : 388)
Query Neighborhood Hits	480	Target Neighborhood Hits	193	Shared Neighborhood Hits	102
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLH13_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.193651 (rank : 387)
Query Neighborhood Hits	480	Target Neighborhood Hits	193	Shared Neighborhood Hits	102
SwissProt Accessions	Q80TF4, Q9DBY7	Gene names	Klhl13, Bklhd2, Kiaa1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLH14_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.185944 (rank : 401)
Query Neighborhood Hits	480	Target Neighborhood Hits	194	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2G3	Gene names	KLHL14, KIAA1384
Domain Architecture	No domain graphic available
Description	Kelch-like protein 14.

KLH20_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.214150 (rank : 366)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y2M5, Q5TZF2, Q9H457	Gene names	KLHL20, KLEIP
Domain Architecture
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch- like protein X).

KLH20_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.214177 (rank : 365)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	102
SwissProt Accessions	Q8VCK5, Q8BWA2	Gene names	Klhl20, Kleip
Domain Architecture	No domain graphic available
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein).

KLHL9_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.192430 (rank : 392)
Query Neighborhood Hits	480	Target Neighborhood Hits	194	Shared Neighborhood Hits	101
SwissProt Accessions	Q9P2J3, Q8TCQ2	Gene names	KLHL9, KIAA1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

KLHL9_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.192672 (rank : 390)
Query Neighborhood Hits	480	Target Neighborhood Hits	195	Shared Neighborhood Hits	101
SwissProt Accessions	Q6ZPT1	Gene names	Klhl9, Kiaa1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

KMHN1_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.053532 (rank : 496)
Query Neighborhood Hits	480	Target Neighborhood Hits	950	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KMHN1_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.054096 (rank : 491)
Query Neighborhood Hits	480	Target Neighborhood Hits	949	Shared Neighborhood Hits	44
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LCE1B_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.055003 (rank : 486)
Query Neighborhood Hits	480	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.051643 (rank : 504)
Query Neighborhood Hits	480	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.052276 (rank : 501)
Query Neighborhood Hits	480	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LRRK1_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.069773 (rank : 469)
Query Neighborhood Hits	480	Target Neighborhood Hits	1267	Shared Neighborhood Hits	121
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MMRN1_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.064601 (rank : 475)
Query Neighborhood Hits	480	Target Neighborhood Hits	636	Shared Neighborhood Hits	41
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

PIBF1_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.053681 (rank : 494)
Query Neighborhood Hits	480	Target Neighborhood Hits	1041	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

RELB_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.054263 (rank : 490)
Query Neighborhood Hits	480	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

RELB_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.054312 (rank : 489)
Query Neighborhood Hits	480	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

REL_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.055311 (rank : 485)
Query Neighborhood Hits	480	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

REL_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.055669 (rank : 483)
Query Neighborhood Hits	480	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

RHBT1_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.067970 (rank : 471)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	81
SwissProt Accessions	Q9DAK3	Gene names	Rhobtb1
Domain Architecture
Description	Rho-related BTB domain-containing protein 1.

RHBT3_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.135510 (rank : 437)
Query Neighborhood Hits	480	Target Neighborhood Hits	116	Shared Neighborhood Hits	71
SwissProt Accessions	O94955, Q8IW06	Gene names	RHOBTB3, KIAA0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

RHBT3_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.135680 (rank : 436)
Query Neighborhood Hits	480	Target Neighborhood Hits	120	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CTN4, Q80X55, Q9CVT0	Gene names	Rhobtb3, Kiaa0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

RSNL2_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.185039 (rank : 402)
Query Neighborhood Hits	480	Target Neighborhood Hits	129	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RUFY3_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.070039 (rank : 468)
Query Neighborhood Hits	480	Target Neighborhood Hits	594	Shared Neighborhood Hits	34
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.065215 (rank : 473)
Query Neighborhood Hits	480	Target Neighborhood Hits	579	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

TF65_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.052950 (rank : 499)
Query Neighborhood Hits	480	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TF65_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.053838 (rank : 493)
Query Neighborhood Hits	480	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TRDN_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.053414 (rank : 498)
Query Neighborhood Hits	480	Target Neighborhood Hits	542	Shared Neighborhood Hits	26
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRIPB_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.050284 (rank : 511)
Query Neighborhood Hits	480	Target Neighborhood Hits	1587	Shared Neighborhood Hits	59
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TRPC1_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.052156 (rank : 502)
Query Neighborhood Hits	480	Target Neighborhood Hits	91	Shared Neighborhood Hits	58
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

ZBT10_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.055332 (rank : 484)
Query Neighborhood Hits	480	Target Neighborhood Hits	831	Shared Neighborhood Hits	101
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

ZBTB3_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.055923 (rank : 482)
Query Neighborhood Hits	480	Target Neighborhood Hits	910	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ZBTB3_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.054736 (rank : 488)
Query Neighborhood Hits	480	Target Neighborhood Hits	792	Shared Neighborhood Hits	89
SwissProt Accessions	Q91X45, Q8BIJ4	Gene names	Zbtb3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

ZBTB8_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.054853 (rank : 487)
Query Neighborhood Hits	480	Target Neighborhood Hits	786	Shared Neighborhood Hits	95
SwissProt Accessions	Q8NAP8, Q5VXR5	Gene names	ZBTB8
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 8.

ZBTB8_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.056300 (rank : 481)
Query Neighborhood Hits	480	Target Neighborhood Hits	791	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CII0	Gene names	Zbtb8
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 8.

ZBTB9_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.060774 (rank : 477)
Query Neighborhood Hits	480	Target Neighborhood Hits	764	Shared Neighborhood Hits	94
SwissProt Accessions	Q96C00	Gene names	ZBTB9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

ZBTB9_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.059175 (rank : 478)
Query Neighborhood Hits	480	Target Neighborhood Hits	780	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

Hits sorted by NC score

ANFY1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	480	Target Neighborhood Hits	480	Shared Neighborhood Hits	480
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.996923 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	480	Target Neighborhood Hits	480	Shared Neighborhood Hits	462
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR50_HUMAN
NC score	0.852118 (rank : 3)	θ value	4.13158e-37 (rank : 12)
Query Neighborhood Hits	480	Target Neighborhood Hits	361	Shared Neighborhood Hits	299
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR44_HUMAN
NC score	0.852057 (rank : 4)	θ value	6.37413e-38 (rank : 11)
Query Neighborhood Hits	480	Target Neighborhood Hits	318	Shared Neighborhood Hits	302
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR28_MOUSE
NC score	0.850711 (rank : 5)	θ value	2.76489e-41 (rank : 7)
Query Neighborhood Hits	480	Target Neighborhood Hits	314	Shared Neighborhood Hits	300
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
NC score	0.849787 (rank : 6)	θ value	5.76516e-39 (rank : 10)
Query Neighborhood Hits	480	Target Neighborhood Hits	314	Shared Neighborhood Hits	300
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_MOUSE
NC score	0.848554 (rank : 7)	θ value	1.05066e-40 (rank : 8)
Query Neighborhood Hits	480	Target Neighborhood Hits	318	Shared Neighborhood Hits	302
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANK1_HUMAN
NC score	0.847867 (rank : 8)	θ value	6.14528e-49 (rank : 5)
Query Neighborhood Hits	480	Target Neighborhood Hits	416	Shared Neighborhood Hits	305
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANR52_HUMAN
NC score	0.847826 (rank : 9)	θ value	2.58786e-39 (rank : 9)
Query Neighborhood Hits	480	Target Neighborhood Hits	322	Shared Neighborhood Hits	302
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANK1_MOUSE
NC score	0.846966 (rank : 10)	θ value	1.36902e-48 (rank : 6)
Query Neighborhood Hits	480	Target Neighborhood Hits	430	Shared Neighborhood Hits	305
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK3_HUMAN
NC score	0.839797 (rank : 11)	θ value	4.69435e-57 (rank : 3)
Query Neighborhood Hits	480	Target Neighborhood Hits	853	Shared Neighborhood Hits	311
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

TNKS1_HUMAN
NC score	0.832887 (rank : 12)	θ value	1.98606e-31 (rank : 13)
Query Neighborhood Hits	480	Target Neighborhood Hits	477	Shared Neighborhood Hits	303
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR16_HUMAN
NC score	0.832365 (rank : 13)	θ value	4.16044e-13 (rank : 81)
Query Neighborhood Hits	480	Target Neighborhood Hits	286	Shared Neighborhood Hits	279
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANKR6_HUMAN
NC score	0.832321 (rank : 14)	θ value	2.27762e-19 (rank : 24)
Query Neighborhood Hits	480	Target Neighborhood Hits	439	Shared Neighborhood Hits	294
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

TNKS2_HUMAN
NC score	0.831919 (rank : 15)	θ value	6.38894e-30 (rank : 14)
Query Neighborhood Hits	480	Target Neighborhood Hits	361	Shared Neighborhood Hits	304
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR29_HUMAN
NC score	0.830276 (rank : 16)	θ value	8.95645e-16 (rank : 37)
Query Neighborhood Hits	480	Target Neighborhood Hits	294	Shared Neighborhood Hits	290
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

INVS_HUMAN
NC score	0.829984 (rank : 17)	θ value	1.62847e-25 (rank : 18)
Query Neighborhood Hits	480	Target Neighborhood Hits	455	Shared Neighborhood Hits	289
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

TRPA1_MOUSE
NC score	0.828516 (rank : 18)	θ value	4.28545e-26 (rank : 17)
Query Neighborhood Hits	480	Target Neighborhood Hits	343	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPA1_HUMAN
NC score	0.828206 (rank : 19)	θ value	1.05554e-24 (rank : 20)
Query Neighborhood Hits	480	Target Neighborhood Hits	339	Shared Neighborhood Hits	300
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

PSD10_HUMAN
NC score	0.827741 (rank : 20)	θ value	2.43908e-13 (rank : 77)
Query Neighborhood Hits	480	Target Neighborhood Hits	301	Shared Neighborhood Hits	291
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.827456 (rank : 21)	θ value	1.42992e-13 (rank : 73)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

INVS_MOUSE
NC score	0.821512 (rank : 22)	θ value	2.77775e-25 (rank : 19)
Query Neighborhood Hits	480	Target Neighborhood Hits	609	Shared Neighborhood Hits	289
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB3_HUMAN
NC score	0.820175 (rank : 23)	θ value	1.99529e-15 (rank : 40)
Query Neighborhood Hits	480	Target Neighborhood Hits	316	Shared Neighborhood Hits	295
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_MOUSE
NC score	0.816512 (rank : 24)	θ value	5.25075e-16 (rank : 36)
Query Neighborhood Hits	480	Target Neighborhood Hits	316	Shared Neighborhood Hits	292
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

FANK1_HUMAN
NC score	0.815925 (rank : 25)	θ value	2.60593e-15 (rank : 41)
Query Neighborhood Hits	480	Target Neighborhood Hits	326	Shared Neighborhood Hits	289
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
NC score	0.814321 (rank : 26)	θ value	2.60593e-15 (rank : 42)
Query Neighborhood Hits	480	Target Neighborhood Hits	325	Shared Neighborhood Hits	284
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

BCL3_HUMAN
NC score	0.814243 (rank : 27)	θ value	3.18553e-13 (rank : 79)
Query Neighborhood Hits	480	Target Neighborhood Hits	324	Shared Neighborhood Hits	289
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ASB2_HUMAN
NC score	0.812041 (rank : 28)	θ value	5.25075e-16 (rank : 35)
Query Neighborhood Hits	480	Target Neighborhood Hits	309	Shared Neighborhood Hits	290
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

BCL3_MOUSE
NC score	0.810206 (rank : 29)	θ value	4.91457e-14 (rank : 62)
Query Neighborhood Hits	480	Target Neighborhood Hits	388	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

PA2G6_MOUSE
NC score	0.809272 (rank : 30)	θ value	1.16975e-15 (rank : 39)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	290
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB7_HUMAN
NC score	0.807399 (rank : 31)	θ value	6.00763e-12 (rank : 93)
Query Neighborhood Hits	480	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

PA2G6_HUMAN
NC score	0.807314 (rank : 32)	θ value	9.90251e-15 (rank : 49)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	280
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB7_MOUSE
NC score	0.807172 (rank : 33)	θ value	6.00763e-12 (rank : 94)
Query Neighborhood Hits	480	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB2_MOUSE
NC score	0.807166 (rank : 34)	θ value	4.02038e-16 (rank : 34)
Query Neighborhood Hits	480	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR42_MOUSE
NC score	0.806537 (rank : 35)	θ value	5.43371e-13 (rank : 82)
Query Neighborhood Hits	480	Target Neighborhood Hits	334	Shared Neighborhood Hits	284
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB10_MOUSE
NC score	0.804372 (rank : 36)	θ value	9.26847e-13 (rank : 88)
Query Neighborhood Hits	480	Target Neighborhood Hits	301	Shared Neighborhood Hits	283
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_HUMAN
NC score	0.802648 (rank : 37)	θ value	6.64225e-11 (rank : 110)
Query Neighborhood Hits	480	Target Neighborhood Hits	291	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANR42_HUMAN
NC score	0.800718 (rank : 38)	θ value	1.02475e-11 (rank : 97)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB8_MOUSE
NC score	0.800517 (rank : 39)	θ value	3.89403e-11 (rank : 106)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANKR7_HUMAN
NC score	0.800036 (rank : 40)	θ value	2.0648e-12 (rank : 89)
Query Neighborhood Hits	480	Target Neighborhood Hits	286	Shared Neighborhood Hits	281
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ASB8_HUMAN
NC score	0.799456 (rank : 41)	θ value	2.52405e-10 (rank : 119)
Query Neighborhood Hits	480	Target Neighborhood Hits	294	Shared Neighborhood Hits	285
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR23_HUMAN
NC score	0.795121 (rank : 42)	θ value	2.79066e-09 (rank : 136)
Query Neighborhood Hits	480	Target Neighborhood Hits	291	Shared Neighborhood Hits	284
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ASB15_HUMAN
NC score	0.791959 (rank : 43)	θ value	3.63628e-17 (rank : 30)
Query Neighborhood Hits	480	Target Neighborhood Hits	305	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB13_MOUSE
NC score	0.789718 (rank : 44)	θ value	4.76016e-09 (rank : 145)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANR23_MOUSE
NC score	0.789070 (rank : 45)	θ value	2.88788e-06 (rank : 230)
Query Neighborhood Hits	480	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB13_HUMAN
NC score	0.788940 (rank : 46)	θ value	2.79066e-09 (rank : 137)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANKR2_MOUSE
NC score	0.788397 (rank : 47)	θ value	3.64472e-09 (rank : 142)
Query Neighborhood Hits	480	Target Neighborhood Hits	312	Shared Neighborhood Hits	287
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR1_MOUSE
NC score	0.787586 (rank : 48)	θ value	4.0297e-08 (rank : 173)
Query Neighborhood Hits	480	Target Neighborhood Hits	316	Shared Neighborhood Hits	289
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKR1_HUMAN
NC score	0.787322 (rank : 49)	θ value	2.61198e-07 (rank : 194)
Query Neighborhood Hits	480	Target Neighborhood Hits	308	Shared Neighborhood Hits	281
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

MIB1_HUMAN
NC score	0.787275 (rank : 50)	θ value	1.47631e-18 (rank : 25)
Query Neighborhood Hits	480	Target Neighborhood Hits	470	Shared Neighborhood Hits	303
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

ANKR2_HUMAN
NC score	0.787093 (rank : 51)	θ value	1.17247e-07 (rank : 179)
Query Neighborhood Hits	480	Target Neighborhood Hits	321	Shared Neighborhood Hits	288
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

MIB1_MOUSE
NC score	0.786965 (rank : 52)	θ value	1.47631e-18 (rank : 26)
Query Neighborhood Hits	480	Target Neighborhood Hits	471	Shared Neighborhood Hits	303
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANK2_HUMAN
NC score	0.786490 (rank : 53)	θ value	4.39379e-55 (rank : 4)
Query Neighborhood Hits	480	Target Neighborhood Hits	1615	Shared Neighborhood Hits	316
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR39_HUMAN
NC score	0.784927 (rank : 54)	θ value	1.09739e-05 (rank : 250)
Query Neighborhood Hits	480	Target Neighborhood Hits	285	Shared Neighborhood Hits	283
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

IKBE_MOUSE
NC score	0.782904 (rank : 55)	θ value	3.52202e-12 (rank : 92)
Query Neighborhood Hits	480	Target Neighborhood Hits	308	Shared Neighborhood Hits	279
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANKS6_MOUSE
NC score	0.780699 (rank : 56)	θ value	4.76016e-09 (rank : 144)
Query Neighborhood Hits	480	Target Neighborhood Hits	435	Shared Neighborhood Hits	293
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKS3_MOUSE
NC score	0.780597 (rank : 57)	θ value	7.34386e-10 (rank : 124)
Query Neighborhood Hits	480	Target Neighborhood Hits	355	Shared Neighborhood Hits	278
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR49_MOUSE
NC score	0.780336 (rank : 58)	θ value	9.92553e-07 (rank : 212)
Query Neighborhood Hits	480	Target Neighborhood Hits	285	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR39_MOUSE
NC score	0.780303 (rank : 59)	θ value	3.19293e-05 (rank : 264)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANKS6_HUMAN
NC score	0.780242 (rank : 60)	θ value	2.13673e-09 (rank : 132)
Query Neighborhood Hits	480	Target Neighborhood Hits	411	Shared Neighborhood Hits	294
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

MIB2_HUMAN
NC score	0.780041 (rank : 61)	θ value	2.20605e-14 (rank : 56)
Query Neighborhood Hits	480	Target Neighborhood Hits	438	Shared Neighborhood Hits	292
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ANKS3_HUMAN
NC score	0.779969 (rank : 62)	θ value	2.52405e-10 (rank : 118)
Query Neighborhood Hits	480	Target Neighborhood Hits	355	Shared Neighborhood Hits	277
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB15_MOUSE
NC score	0.779915 (rank : 63)	θ value	1.29331e-14 (rank : 52)
Query Neighborhood Hits	480	Target Neighborhood Hits	292	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

GABP2_MOUSE
NC score	0.779311 (rank : 64)	θ value	3.08544e-08 (rank : 171)
Query Neighborhood Hits	480	Target Neighborhood Hits	429	Shared Neighborhood Hits	292
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ASB16_MOUSE
NC score	0.778825 (rank : 65)	θ value	1.17247e-07 (rank : 180)
Query Neighborhood Hits	480	Target Neighborhood Hits	306	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

AN36B_HUMAN
NC score	0.778723 (rank : 66)	θ value	6.64225e-11 (rank : 108)
Query Neighborhood Hits	480	Target Neighborhood Hits	294	Shared Neighborhood Hits	286
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

GABP2_HUMAN
NC score	0.778174 (rank : 67)	θ value	1.80886e-08 (rank : 168)
Query Neighborhood Hits	480	Target Neighborhood Hits	454	Shared Neighborhood Hits	293
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ASB14_MOUSE
NC score	0.778036 (rank : 68)	θ value	9.90251e-15 (rank : 47)
Query Neighborhood Hits	480	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

MIB2_MOUSE
NC score	0.777880 (rank : 69)	θ value	9.90251e-15 (rank : 48)
Query Neighborhood Hits	480	Target Neighborhood Hits	409	Shared Neighborhood Hits	285
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANKS1_HUMAN
NC score	0.777871 (rank : 70)	θ value	7.58209e-15 (rank : 46)
Query Neighborhood Hits	480	Target Neighborhood Hits	438	Shared Neighborhood Hits	300
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

IKBA_HUMAN
NC score	0.777750 (rank : 71)	θ value	8.11959e-09 (rank : 156)
Query Neighborhood Hits	480	Target Neighborhood Hits	280	Shared Neighborhood Hits	276
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANKR5_HUMAN
NC score	0.776038 (rank : 72)	θ value	2.28291e-11 (rank : 102)
Query Neighborhood Hits	480	Target Neighborhood Hits	297	Shared Neighborhood Hits	280
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR49_HUMAN
NC score	0.775645 (rank : 73)	θ value	1.69304e-06 (rank : 222)
Query Neighborhood Hits	480	Target Neighborhood Hits	282	Shared Neighborhood Hits	275
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

PP16A_MOUSE
NC score	0.775257 (rank : 74)	θ value	5.43371e-13 (rank : 85)
Query Neighborhood Hits	480	Target Neighborhood Hits	318	Shared Neighborhood Hits	283
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2C_MOUSE
NC score	0.775138 (rank : 75)	θ value	6.21693e-09 (rank : 148)
Query Neighborhood Hits	480	Target Neighborhood Hits	270	Shared Neighborhood Hits	269
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

GABP3_MOUSE
NC score	0.774359 (rank : 76)	θ value	1.69304e-06 (rank : 225)
Query Neighborhood Hits	480	Target Neighborhood Hits	330	Shared Neighborhood Hits	279
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

CDN2C_HUMAN
NC score	0.773899 (rank : 77)	θ value	1.06045e-08 (rank : 162)
Query Neighborhood Hits	480	Target Neighborhood Hits	262	Shared Neighborhood Hits	261
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANKR5_MOUSE
NC score	0.773240 (rank : 78)	θ value	1.74796e-11 (rank : 100)
Query Neighborhood Hits	480	Target Neighborhood Hits	298	Shared Neighborhood Hits	279
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB16_HUMAN
NC score	0.772885 (rank : 79)	θ value	4.76016e-09 (rank : 146)
Query Neighborhood Hits	480	Target Neighborhood Hits	286	Shared Neighborhood Hits	273
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

MYPT1_MOUSE
NC score	0.771312 (rank : 80)	θ value	1.74796e-11 (rank : 101)
Query Neighborhood Hits	480	Target Neighborhood Hits	539	Shared Neighborhood Hits	295
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

IKBA_MOUSE
NC score	0.770356 (rank : 81)	θ value	4.76016e-09 (rank : 147)
Query Neighborhood Hits	480	Target Neighborhood Hits	283	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

CDN2D_HUMAN
NC score	0.768500 (rank : 82)	θ value	1.80886e-08 (rank : 167)
Query Neighborhood Hits	480	Target Neighborhood Hits	268	Shared Neighborhood Hits	265
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CDN2D_MOUSE
NC score	0.767588 (rank : 83)	θ value	2.79066e-09 (rank : 138)
Query Neighborhood Hits	480	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

RN5A_HUMAN
NC score	0.766886 (rank : 84)	θ value	6.41864e-14 (rank : 66)
Query Neighborhood Hits	480	Target Neighborhood Hits	608	Shared Neighborhood Hits	287
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

PP16A_HUMAN
NC score	0.766707 (rank : 85)	θ value	3.89403e-11 (rank : 107)
Query Neighborhood Hits	480	Target Neighborhood Hits	340	Shared Neighborhood Hits	278
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

IKBE_HUMAN
NC score	0.766498 (rank : 86)	θ value	1.133e-10 (rank : 114)
Query Neighborhood Hits	480	Target Neighborhood Hits	288	Shared Neighborhood Hits	269
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

POTE8_HUMAN
NC score	0.764080 (rank : 87)	θ value	1.09485e-13 (rank : 70)
Query Neighborhood Hits	480	Target Neighborhood Hits	337	Shared Neighborhood Hits	291
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANKS1_MOUSE
NC score	0.763608 (rank : 88)	θ value	1.42992e-13 (rank : 72)
Query Neighborhood Hits	480	Target Neighborhood Hits	453	Shared Neighborhood Hits	293
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR35_HUMAN
NC score	0.763262 (rank : 89)	θ value	7.32683e-18 (rank : 28)
Query Neighborhood Hits	480	Target Neighborhood Hits	784	Shared Neighborhood Hits	308
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB5_HUMAN
NC score	0.761370 (rank : 90)	θ value	5.43371e-13 (rank : 83)
Query Neighborhood Hits	480	Target Neighborhood Hits	283	Shared Neighborhood Hits	270
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANR19_HUMAN
NC score	0.761030 (rank : 91)	θ value	2.69671e-12 (rank : 90)
Query Neighborhood Hits	480	Target Neighborhood Hits	276	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

IKBB_MOUSE
NC score	0.761008 (rank : 92)	θ value	2.98157e-11 (rank : 105)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

MYPT2_HUMAN
NC score	0.760720 (rank : 93)	θ value	1.68911e-14 (rank : 54)
Query Neighborhood Hits	480	Target Neighborhood Hits	707	Shared Neighborhood Hits	299
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ASB4_MOUSE
NC score	0.759881 (rank : 94)	θ value	3.41135e-07 (rank : 201)
Query Neighborhood Hits	480	Target Neighborhood Hits	265	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_HUMAN
NC score	0.759410 (rank : 95)	θ value	3.41135e-07 (rank : 200)
Query Neighborhood Hits	480	Target Neighborhood Hits	264	Shared Neighborhood Hits	259
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB5_MOUSE
NC score	0.758864 (rank : 96)	θ value	2.69671e-12 (rank : 91)
Query Neighborhood Hits	480	Target Neighborhood Hits	266	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

PP16B_HUMAN
NC score	0.757563 (rank : 97)	θ value	1.17247e-07 (rank : 182)
Query Neighborhood Hits	480	Target Neighborhood Hits	307	Shared Neighborhood Hits	282
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

MTPN_MOUSE
NC score	0.757522 (rank : 98)	θ value	9.29e-05 (rank : 290)
Query Neighborhood Hits	480	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

IKBB_HUMAN
NC score	0.757174 (rank : 99)	θ value	2.79066e-09 (rank : 139)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

PP16B_MOUSE
NC score	0.756745 (rank : 100)	θ value	5.26297e-08 (rank : 175)
Query Neighborhood Hits	480	Target Neighborhood Hits	302	Shared Neighborhood Hits	282
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR22_HUMAN
NC score	0.756596 (rank : 101)	θ value	5.44631e-05 (rank : 276)
Query Neighborhood Hits	480	Target Neighborhood Hits	243	Shared Neighborhood Hits	243
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASZ1_MOUSE
NC score	0.756536 (rank : 102)	θ value	2.88788e-06 (rank : 231)
Query Neighborhood Hits	480	Target Neighborhood Hits	319	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANR46_HUMAN
NC score	0.756302 (rank : 103)	θ value	3.77169e-06 (rank : 235)
Query Neighborhood Hits	480	Target Neighborhood Hits	281	Shared Neighborhood Hits	274
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASB9_HUMAN
NC score	0.756057 (rank : 104)	θ value	9.59137e-10 (rank : 125)
Query Neighborhood Hits	480	Target Neighborhood Hits	267	Shared Neighborhood Hits	255
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MYPT1_HUMAN
NC score	0.755732 (rank : 105)	θ value	2.28291e-11 (rank : 103)
Query Neighborhood Hits	480	Target Neighborhood Hits	723	Shared Neighborhood Hits	303
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ASB11_MOUSE
NC score	0.754701 (rank : 106)	θ value	2.13673e-09 (rank : 133)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	257
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

CT086_HUMAN
NC score	0.753955 (rank : 107)	θ value	1.43324e-05 (rank : 254)
Query Neighborhood Hits	480	Target Neighborhood Hits	277	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

MTPN_HUMAN
NC score	0.753200 (rank : 108)	θ value	5.44631e-05 (rank : 283)
Query Neighborhood Hits	480	Target Neighborhood Hits	269	Shared Neighborhood Hits	267
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ASB11_HUMAN
NC score	0.751627 (rank : 109)	θ value	1.99992e-07 (rank : 187)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	260
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASZ1_HUMAN
NC score	0.750862 (rank : 110)	θ value	0.000270298 (rank : 302)
Query Neighborhood Hits	480	Target Neighborhood Hits	341	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CSKI2_MOUSE
NC score	0.748036 (rank : 111)	θ value	3.18553e-13 (rank : 80)
Query Neighborhood Hits	480	Target Neighborhood Hits	812	Shared Neighborhood Hits	291
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR46_MOUSE
NC score	0.747937 (rank : 112)	θ value	8.40245e-06 (rank : 248)
Query Neighborhood Hits	480	Target Neighborhood Hits	274	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

EHMT1_HUMAN
NC score	0.747716 (rank : 113)	θ value	1.33837e-11 (rank : 99)
Query Neighborhood Hits	480	Target Neighborhood Hits	417	Shared Neighborhood Hits	296
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

CSKI2_HUMAN
NC score	0.747653 (rank : 114)	θ value	2.43908e-13 (rank : 75)
Query Neighborhood Hits	480	Target Neighborhood Hits	747	Shared Neighborhood Hits	295
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR10_HUMAN
NC score	0.745718 (rank : 115)	θ value	3.41135e-07 (rank : 198)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	267
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

CSKI1_HUMAN
NC score	0.745191 (rank : 116)	θ value	6.41864e-14 (rank : 63)
Query Neighborhood Hits	480	Target Neighborhood Hits	997	Shared Neighborhood Hits	293
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ASB9_MOUSE
NC score	0.743938 (rank : 117)	θ value	4.0297e-08 (rank : 174)
Query Neighborhood Hits	480	Target Neighborhood Hits	257	Shared Neighborhood Hits	249
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CSKI1_MOUSE
NC score	0.743767 (rank : 118)	θ value	6.41864e-14 (rank : 64)
Query Neighborhood Hits	480	Target Neighborhood Hits	1031	Shared Neighborhood Hits	294
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR10_MOUSE
NC score	0.741969 (rank : 119)	θ value	4.92598e-06 (rank : 240)
Query Neighborhood Hits	480	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

EHMT2_HUMAN
NC score	0.741477 (rank : 120)	θ value	2.43908e-13 (rank : 76)
Query Neighborhood Hits	480	Target Neighborhood Hits	498	Shared Neighborhood Hits	300
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANRA2_HUMAN
NC score	0.741310 (rank : 121)	θ value	0.00020696 (rank : 295)
Query Neighborhood Hits	480	Target Neighborhood Hits	288	Shared Neighborhood Hits	277
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

AN36A_HUMAN
NC score	0.741178 (rank : 122)	θ value	4.92598e-06 (rank : 239)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	271
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

RFXK_HUMAN
NC score	0.740961 (rank : 123)	θ value	3.19293e-05 (rank : 265)
Query Neighborhood Hits	480	Target Neighborhood Hits	282	Shared Neighborhood Hits	264
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANRA2_MOUSE
NC score	0.740569 (rank : 124)	θ value	0.00020696 (rank : 296)
Query Neighborhood Hits	480	Target Neighborhood Hits	287	Shared Neighborhood Hits	277
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ACBD6_MOUSE
NC score	0.736997 (rank : 125)	θ value	5.81887e-07 (rank : 210)
Query Neighborhood Hits	480	Target Neighborhood Hits	305	Shared Neighborhood Hits	291
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

RFXK_MOUSE
NC score	0.734674 (rank : 126)	θ value	5.44631e-05 (rank : 285)
Query Neighborhood Hits	480	Target Neighborhood Hits	273	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ACBD6_HUMAN
NC score	0.732422 (rank : 127)	θ value	4.92598e-06 (rank : 238)
Query Neighborhood Hits	480	Target Neighborhood Hits	304	Shared Neighborhood Hits	287
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASB12_HUMAN
NC score	0.726449 (rank : 128)	θ value	0.000461057 (rank : 310)
Query Neighborhood Hits	480	Target Neighborhood Hits	263	Shared Neighborhood Hits	260
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

EHMT2_MOUSE
NC score	0.726149 (rank : 129)	θ value	5.43371e-13 (rank : 84)
Query Neighborhood Hits	480	Target Neighborhood Hits	750	Shared Neighborhood Hits	299
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB12_MOUSE
NC score	0.724713 (rank : 130)	θ value	7.1131e-05 (rank : 286)
Query Neighborhood Hits	480	Target Neighborhood Hits	261	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

POT15_HUMAN
NC score	0.722177 (rank : 131)	θ value	2.20605e-14 (rank : 59)
Query Neighborhood Hits	480	Target Neighborhood Hits	893	Shared Neighborhood Hits	303
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANR21_HUMAN
NC score	0.721407 (rank : 132)	θ value	1.29331e-14 (rank : 51)
Query Neighborhood Hits	480	Target Neighborhood Hits	864	Shared Neighborhood Hits	303
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

BARD1_MOUSE
NC score	0.719429 (rank : 133)	θ value	1.69304e-06 (rank : 223)
Query Neighborhood Hits	480	Target Neighborhood Hits	411	Shared Neighborhood Hits	281
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_HUMAN
NC score	0.719345 (rank : 134)	θ value	4.1701e-05 (rank : 270)
Query Neighborhood Hits	480	Target Neighborhood Hits	427	Shared Neighborhood Hits	288
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB1_HUMAN
NC score	0.718581 (rank : 135)	θ value	0.00390308 (rank : 345)
Query Neighborhood Hits	480	Target Neighborhood Hits	291	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_MOUSE
NC score	0.717465 (rank : 136)	θ value	0.00228821 (rank : 339)
Query Neighborhood Hits	480	Target Neighborhood Hits	292	Shared Neighborhood Hits	276
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

RN5A_MOUSE
NC score	0.714109 (rank : 137)	θ value	7.84624e-12 (rank : 96)
Query Neighborhood Hits	480	Target Neighborhood Hits	899	Shared Neighborhood Hits	297
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR32_HUMAN
NC score	0.711711 (rank : 138)	θ value	3.77169e-06 (rank : 234)
Query Neighborhood Hits	480	Target Neighborhood Hits	270	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

POT14_HUMAN
NC score	0.709340 (rank : 139)	θ value	2.20605e-14 (rank : 58)
Query Neighborhood Hits	480	Target Neighborhood Hits	403	Shared Neighborhood Hits	273
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ASB6_MOUSE
NC score	0.705772 (rank : 140)	θ value	2.44474e-05 (rank : 259)
Query Neighborhood Hits	480	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

NFKB1_MOUSE
NC score	0.705671 (rank : 141)	θ value	6.41864e-14 (rank : 65)
Query Neighborhood Hits	480	Target Neighborhood Hits	300	Shared Neighborhood Hits	269
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NFKB1_HUMAN
NC score	0.705490 (rank : 142)	θ value	7.09661e-13 (rank : 86)
Query Neighborhood Hits	480	Target Neighborhood Hits	306	Shared Neighborhood Hits	278
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ASB6_HUMAN
NC score	0.701417 (rank : 143)	θ value	0.00102713 (rank : 325)
Query Neighborhood Hits	480	Target Neighborhood Hits	256	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR47_MOUSE
NC score	0.700873 (rank : 144)	θ value	6.64225e-11 (rank : 109)
Query Neighborhood Hits	480	Target Neighborhood Hits	350	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR32_MOUSE
NC score	0.697207 (rank : 145)	θ value	4.1701e-05 (rank : 266)
Query Neighborhood Hits	480	Target Neighborhood Hits	285	Shared Neighborhood Hits	262
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

NFKB2_HUMAN
NC score	0.695320 (rank : 146)	θ value	4.30538e-10 (rank : 120)
Query Neighborhood Hits	480	Target Neighborhood Hits	325	Shared Neighborhood Hits	281
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANS4B_HUMAN
NC score	0.694154 (rank : 147)	θ value	0.000121331 (rank : 292)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH17_HUMAN
NC score	0.693142 (rank : 148)	θ value	1.63604e-09 (rank : 129)
Query Neighborhood Hits	480	Target Neighborhood Hits	334	Shared Neighborhood Hits	280
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ZDH13_HUMAN
NC score	0.692724 (rank : 149)	θ value	6.21693e-09 (rank : 154)
Query Neighborhood Hits	480	Target Neighborhood Hits	322	Shared Neighborhood Hits	278
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

CTTB2_HUMAN
NC score	0.691688 (rank : 150)	θ value	2.98157e-11 (rank : 104)
Query Neighborhood Hits	480	Target Neighborhood Hits	1061	Shared Neighborhood Hits	312
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR15_HUMAN
NC score	0.691052 (rank : 151)	θ value	1.29631e-06 (rank : 218)
Query Neighborhood Hits	480	Target Neighborhood Hits	478	Shared Neighborhood Hits	279
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

USH1G_MOUSE
NC score	0.689730 (rank : 152)	θ value	0.00020696 (rank : 299)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.689531 (rank : 153)	θ value	0.00020696 (rank : 298)
Query Neighborhood Hits	480	Target Neighborhood Hits	267	Shared Neighborhood Hits	260
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ZDH17_MOUSE
NC score	0.687834 (rank : 154)	θ value	2.79066e-09 (rank : 141)
Query Neighborhood Hits	480	Target Neighborhood Hits	328	Shared Neighborhood Hits	275
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ZDH13_MOUSE
NC score	0.686539 (rank : 155)	θ value	1.99992e-07 (rank : 193)
Query Neighborhood Hits	480	Target Neighborhood Hits	329	Shared Neighborhood Hits	280
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANR41_HUMAN
NC score	0.686458 (rank : 156)	θ value	0.00390308 (rank : 344)
Query Neighborhood Hits	480	Target Neighborhood Hits	332	Shared Neighborhood Hits	255
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

NFKB2_MOUSE
NC score	0.685210 (rank : 157)	θ value	6.64225e-11 (rank : 111)
Query Neighborhood Hits	480	Target Neighborhood Hits	326	Shared Neighborhood Hits	277
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANS4B_MOUSE
NC score	0.683530 (rank : 158)	θ value	0.000602161 (rank : 313)
Query Neighborhood Hits	480	Target Neighborhood Hits	294	Shared Neighborhood Hits	254
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR47_HUMAN
NC score	0.682283 (rank : 159)	θ value	3.64472e-09 (rank : 143)
Query Neighborhood Hits	480	Target Neighborhood Hits	369	Shared Neighborhood Hits	254
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

SNCAP_HUMAN
NC score	0.681509 (rank : 160)	θ value	3.08544e-08 (rank : 172)
Query Neighborhood Hits	480	Target Neighborhood Hits	313	Shared Neighborhood Hits	237
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ANR11_HUMAN
NC score	0.678203 (rank : 161)	θ value	3.41135e-07 (rank : 199)
Query Neighborhood Hits	480	Target Neighborhood Hits	1289	Shared Neighborhood Hits	292
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR37_HUMAN
NC score	0.670012 (rank : 162)	θ value	0.00175202 (rank : 335)
Query Neighborhood Hits	480	Target Neighborhood Hits	247	Shared Neighborhood Hits	246
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANKY2_HUMAN
NC score	0.669906 (rank : 163)	θ value	0.00390308 (rank : 343)
Query Neighborhood Hits	480	Target Neighborhood Hits	306	Shared Neighborhood Hits	266
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

A20A3_HUMAN
NC score	0.664534 (rank : 164)	θ value	1.09485e-13 (rank : 68)
Query Neighborhood Hits	480	Target Neighborhood Hits	692	Shared Neighborhood Hits	284
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

ANR37_MOUSE
NC score	0.663526 (rank : 165)	θ value	4.1701e-05 (rank : 267)
Query Neighborhood Hits	480	Target Neighborhood Hits	237	Shared Neighborhood Hits	236
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR12_HUMAN
NC score	0.663266 (rank : 166)	θ value	1.47974e-10 (rank : 115)
Query Neighborhood Hits	480	Target Neighborhood Hits	1081	Shared Neighborhood Hits	297
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

A20A1_HUMAN
NC score	0.662564 (rank : 167)	θ value	1.09485e-13 (rank : 67)
Query Neighborhood Hits	480	Target Neighborhood Hits	698	Shared Neighborhood Hits	283
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
NC score	0.662525 (rank : 168)	θ value	1.42992e-13 (rank : 71)
Query Neighborhood Hits	480	Target Neighborhood Hits	716	Shared Neighborhood Hits	286
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

POT22_HUMAN
NC score	0.661394 (rank : 169)	θ value	2.88788e-06 (rank : 233)
Query Neighborhood Hits	480	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

SHAN1_HUMAN
NC score	0.659916 (rank : 170)	θ value	6.21693e-09 (rank : 153)
Query Neighborhood Hits	480	Target Neighborhood Hits	1041	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR25_HUMAN
NC score	0.659865 (rank : 171)	θ value	1.53129e-07 (rank : 183)
Query Neighborhood Hits	480	Target Neighborhood Hits	350	Shared Neighborhood Hits	255
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

A20A4_HUMAN
NC score	0.659500 (rank : 172)	θ value	1.09485e-13 (rank : 69)
Query Neighborhood Hits	480	Target Neighborhood Hits	710	Shared Neighborhood Hits	284
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

BCOR_MOUSE
NC score	0.656076 (rank : 173)	θ value	1.29631e-06 (rank : 219)
Query Neighborhood Hits	480	Target Neighborhood Hits	521	Shared Neighborhood Hits	278
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR38_HUMAN
NC score	0.650950 (rank : 174)	θ value	2.61198e-07 (rank : 195)
Query Neighborhood Hits	480	Target Neighborhood Hits	443	Shared Neighborhood Hits	247
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ABTB2_HUMAN
NC score	0.649446 (rank : 175)	θ value	1.09739e-05 (rank : 249)
Query Neighborhood Hits	480	Target Neighborhood Hits	391	Shared Neighborhood Hits	310
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR33_MOUSE
NC score	0.648654 (rank : 176)	θ value	0.0148317 (rank : 365)
Query Neighborhood Hits	480	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

BCOR_HUMAN
NC score	0.647850 (rank : 177)	θ value	1.69304e-06 (rank : 224)
Query Neighborhood Hits	480	Target Neighborhood Hits	609	Shared Neighborhood Hits	279
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR25_MOUSE
NC score	0.647324 (rank : 178)	θ value	1.53129e-07 (rank : 184)
Query Neighborhood Hits	480	Target Neighborhood Hits	398	Shared Neighborhood Hits	258
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ABTB2_MOUSE
NC score	0.646590 (rank : 179)	θ value	2.88788e-06 (rank : 229)
Query Neighborhood Hits	480	Target Neighborhood Hits	414	Shared Neighborhood Hits	310
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANKY2_MOUSE
NC score	0.645733 (rank : 180)	θ value	0.0431538 (rank : 375)
Query Neighborhood Hits	480	Target Neighborhood Hits	316	Shared Neighborhood Hits	266
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

KRIT1_MOUSE
NC score	0.642051 (rank : 181)	θ value	1.06045e-08 (rank : 163)
Query Neighborhood Hits	480	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MPP8_HUMAN
NC score	0.637389 (rank : 182)	θ value	7.84624e-12 (rank : 95)
Query Neighborhood Hits	480	Target Neighborhood Hits	948	Shared Neighborhood Hits	264
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

KRIT1_HUMAN
NC score	0.636104 (rank : 183)	θ value	2.61198e-07 (rank : 197)
Query Neighborhood Hits	480	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

ANR38_MOUSE
NC score	0.629618 (rank : 184)	θ value	4.92598e-06 (rank : 241)
Query Neighborhood Hits	480	Target Neighborhood Hits	512	Shared Neighborhood Hits	241
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR33_HUMAN
NC score	0.628709 (rank : 185)	θ value	0.163984 (rank : 386)
Query Neighborhood Hits	480	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CD2A1_MOUSE
NC score	0.624787 (rank : 186)	θ value	0.21417 (rank : 392)
Query Neighborhood Hits	480	Target Neighborhood Hits	206	Shared Neighborhood Hits	202
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CLPB_MOUSE
NC score	0.624696 (rank : 187)	θ value	0.00509761 (rank : 352)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	249
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

OSBL1_HUMAN
NC score	0.619887 (rank : 188)	θ value	2.13673e-09 (rank : 134)
Query Neighborhood Hits	480	Target Neighborhood Hits	368	Shared Neighborhood Hits	283
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR18_HUMAN
NC score	0.619771 (rank : 189)	θ value	3.18553e-13 (rank : 78)
Query Neighborhood Hits	480	Target Neighborhood Hits	1106	Shared Neighborhood Hits	292
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

RAI14_HUMAN
NC score	0.619395 (rank : 190)	θ value	9.56915e-18 (rank : 29)
Query Neighborhood Hits	480	Target Neighborhood Hits	1367	Shared Neighborhood Hits	317
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

OSBL1_MOUSE
NC score	0.606258 (rank : 191)	θ value	1.17247e-07 (rank : 181)
Query Neighborhood Hits	480	Target Neighborhood Hits	336	Shared Neighborhood Hits	282
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

RAI14_MOUSE
NC score	0.587883 (rank : 192)	θ value	2.5182e-18 (rank : 27)
Query Neighborhood Hits	480	Target Neighborhood Hits	1505	Shared Neighborhood Hits	311
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CDN2B_MOUSE
NC score	0.585931 (rank : 193)	θ value	0.47712 (rank : 404)
Query Neighborhood Hits	480	Target Neighborhood Hits	201	Shared Neighborhood Hits	195
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

AN30A_HUMAN
NC score	0.584194 (rank : 194)	θ value	4.02038e-16 (rank : 33)
Query Neighborhood Hits	480	Target Neighborhood Hits	1119	Shared Neighborhood Hits	282
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

OSTF1_MOUSE
NC score	0.581359 (rank : 195)	θ value	0.00102713 (rank : 330)
Query Neighborhood Hits	480	Target Neighborhood Hits	467	Shared Neighborhood Hits	254
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANR45_MOUSE
NC score	0.568424 (rank : 196)	θ value	0.00509761 (rank : 350)
Query Neighborhood Hits	480	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

OSTF1_HUMAN
NC score	0.568176 (rank : 197)	θ value	0.000602161 (rank : 315)
Query Neighborhood Hits	480	Target Neighborhood Hits	466	Shared Neighborhood Hits	252
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

TRPV6_MOUSE
NC score	0.563657 (rank : 198)	θ value	4.45536e-07 (rank : 209)
Query Neighborhood Hits	480	Target Neighborhood Hits	284	Shared Neighborhood Hits	260
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR43_HUMAN
NC score	0.558323 (rank : 199)	θ value	0.163984 (rank : 387)
Query Neighborhood Hits	480	Target Neighborhood Hits	209	Shared Neighborhood Hits	201
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CD2A1_HUMAN
NC score	0.551619 (rank : 200)	θ value	1.38821 (rank : 421)
Query Neighborhood Hits	480	Target Neighborhood Hits	196	Shared Neighborhood Hits	190
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

HECD1_HUMAN
NC score	0.550306 (rank : 201)	θ value	0.000121331 (rank : 293)
Query Neighborhood Hits	480	Target Neighborhood Hits	371	Shared Neighborhood Hits	273
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ANR43_MOUSE
NC score	0.547169 (rank : 202)	θ value	0.21417 (rank : 390)
Query Neighborhood Hits	480	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CDN2B_HUMAN
NC score	0.541399 (rank : 203)	θ value	1.81305 (rank : 427)
Query Neighborhood Hits	480	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ANKY1_HUMAN
NC score	0.537280 (rank : 204)	θ value	0.00298849 (rank : 341)
Query Neighborhood Hits	480	Target Neighborhood Hits	248	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANKK1_HUMAN
NC score	0.537091 (rank : 205)	θ value	2.68423e-28 (rank : 16)
Query Neighborhood Hits	480	Target Neighborhood Hits	1075	Shared Neighborhood Hits	300
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

CLPB_HUMAN
NC score	0.530883 (rank : 206)	θ value	1.38821 (rank : 422)
Query Neighborhood Hits	480	Target Neighborhood Hits	265	Shared Neighborhood Hits	238
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR45_HUMAN
NC score	0.530864 (rank : 207)	θ value	0.0330416 (rank : 373)
Query Neighborhood Hits	480	Target Neighborhood Hits	201	Shared Neighborhood Hits	185
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

RIPK4_HUMAN
NC score	0.525665 (rank : 208)	θ value	9.87957e-23 (rank : 21)
Query Neighborhood Hits	480	Target Neighborhood Hits	1094	Shared Neighborhood Hits	304
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKK1_MOUSE
NC score	0.524581 (rank : 209)	θ value	7.06379e-29 (rank : 15)
Query Neighborhood Hits	480	Target Neighborhood Hits	1072	Shared Neighborhood Hits	297
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ASPP2_HUMAN
NC score	0.521359 (rank : 210)	θ value	9.29e-05 (rank : 289)
Query Neighborhood Hits	480	Target Neighborhood Hits	1156	Shared Neighborhood Hits	286
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

IASPP_HUMAN
NC score	0.518614 (rank : 211)	θ value	5.44631e-05 (rank : 281)
Query Neighborhood Hits	480	Target Neighborhood Hits	688	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TRPV5_MOUSE
NC score	0.518298 (rank : 212)	θ value	4.45536e-07 (rank : 208)
Query Neighborhood Hits	480	Target Neighborhood Hits	278	Shared Neighborhood Hits	253
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR40_HUMAN
NC score	0.518282 (rank : 213)	θ value	0.47712 (rank : 403)
Query Neighborhood Hits	480	Target Neighborhood Hits	224	Shared Neighborhood Hits	199
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
NC score	0.516135 (rank : 214)	θ value	0.365318 (rank : 399)
Query Neighborhood Hits	480	Target Neighborhood Hits	228	Shared Neighborhood Hits	203
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CENB5_HUMAN
NC score	0.508417 (rank : 215)	θ value	0.00509761 (rank : 351)
Query Neighborhood Hits	480	Target Neighborhood Hits	395	Shared Neighborhood Hits	270
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ASPP1_HUMAN
NC score	0.508351 (rank : 216)	θ value	4.1701e-05 (rank : 268)
Query Neighborhood Hits	480	Target Neighborhood Hits	956	Shared Neighborhood Hits	275
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CENB1_HUMAN
NC score	0.507580 (rank : 217)	θ value	0.000786445 (rank : 319)
Query Neighborhood Hits	480	Target Neighborhood Hits	383	Shared Neighborhood Hits	259
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

NUD12_MOUSE
NC score	0.502167 (rank : 218)	θ value	0.813845 (rank : 410)
Query Neighborhood Hits	480	Target Neighborhood Hits	243	Shared Neighborhood Hits	222
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

UACA_HUMAN
NC score	0.499263 (rank : 219)	θ value	1.42992e-13 (rank : 74)
Query Neighborhood Hits	480	Target Neighborhood Hits	1622	Shared Neighborhood Hits	313
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

CENB2_HUMAN
NC score	0.498466 (rank : 220)	θ value	5.44631e-05 (rank : 277)
Query Neighborhood Hits	480	Target Neighborhood Hits	425	Shared Neighborhood Hits	260
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

AN13C_HUMAN
NC score	0.495782 (rank : 221)	θ value	0.000270298 (rank : 301)
Query Neighborhood Hits	480	Target Neighborhood Hits	241	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ASB14_HUMAN
NC score	0.494810 (rank : 222)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	480	Target Neighborhood Hits	187	Shared Neighborhood Hits	172
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

TRPV5_HUMAN
NC score	0.493818 (rank : 223)	θ value	6.43352e-06 (rank : 247)
Query Neighborhood Hits	480	Target Neighborhood Hits	261	Shared Neighborhood Hits	231
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

AN13B_MOUSE
NC score	0.493473 (rank : 224)	θ value	0.00102713 (rank : 324)
Query Neighborhood Hits	480	Target Neighborhood Hits	276	Shared Neighborhood Hits	254
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.492961 (rank : 225)	θ value	0.00102713 (rank : 323)
Query Neighborhood Hits	480	Target Neighborhood Hits	265	Shared Neighborhood Hits	254
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

TRPV6_HUMAN
NC score	0.492464 (rank : 226)	θ value	4.1701e-05 (rank : 275)
Query Neighborhood Hits	480	Target Neighborhood Hits	262	Shared Neighborhood Hits	233
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

ASPP1_MOUSE
NC score	0.491948 (rank : 227)	θ value	4.1701e-05 (rank : 269)
Query Neighborhood Hits	480	Target Neighborhood Hits	1244	Shared Neighborhood Hits	281
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

AN13C_MOUSE
NC score	0.484996 (rank : 228)	θ value	0.000602161 (rank : 312)
Query Neighborhood Hits	480	Target Neighborhood Hits	242	Shared Neighborhood Hits	234
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ILK2_HUMAN
NC score	0.479697 (rank : 229)	θ value	1.99992e-07 (rank : 190)
Query Neighborhood Hits	480	Target Neighborhood Hits	848	Shared Neighborhood Hits	286
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

NUD12_HUMAN
NC score	0.478851 (rank : 230)	θ value	0.163984 (rank : 388)
Query Neighborhood Hits	480	Target Neighborhood Hits	222	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

UACA_MOUSE
NC score	0.476271 (rank : 231)	θ value	2.88119e-14 (rank : 60)
Query Neighborhood Hits	480	Target Neighborhood Hits	1620	Shared Neighborhood Hits	307
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GIT2_MOUSE
NC score	0.472692 (rank : 232)	θ value	0.000270298 (rank : 303)
Query Neighborhood Hits	480	Target Neighborhood Hits	323	Shared Neighborhood Hits	252
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

IASPP_MOUSE
NC score	0.466483 (rank : 233)	θ value	0.00102713 (rank : 328)
Query Neighborhood Hits	480	Target Neighborhood Hits	1024	Shared Neighborhood Hits	261
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANR26_MOUSE
NC score	0.465916 (rank : 234)	θ value	9.26847e-13 (rank : 87)
Query Neighborhood Hits	480	Target Neighborhood Hits	1554	Shared Neighborhood Hits	307
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ILK1_HUMAN
NC score	0.463219 (rank : 235)	θ value	1.99992e-07 (rank : 189)
Query Neighborhood Hits	480	Target Neighborhood Hits	857	Shared Neighborhood Hits	286
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK_MOUSE
NC score	0.460772 (rank : 236)	θ value	3.41135e-07 (rank : 202)
Query Neighborhood Hits	480	Target Neighborhood Hits	858	Shared Neighborhood Hits	285
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

GIT1_MOUSE
NC score	0.459197 (rank : 237)	θ value	0.00390308 (rank : 348)
Query Neighborhood Hits	480	Target Neighborhood Hits	341	Shared Neighborhood Hits	250
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.457683 (rank : 238)	θ value	0.00390308 (rank : 347)
Query Neighborhood Hits	480	Target Neighborhood Hits	336	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GLSL_HUMAN
NC score	0.454627 (rank : 239)	θ value	0.365318 (rank : 400)
Query Neighborhood Hits	480	Target Neighborhood Hits	211	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ANR26_HUMAN
NC score	0.449737 (rank : 240)	θ value	1.33837e-11 (rank : 98)
Query Neighborhood Hits	480	Target Neighborhood Hits	1614	Shared Neighborhood Hits	313
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC4_MOUSE
NC score	0.446049 (rank : 241)	θ value	2.60593e-15 (rank : 43)
Query Neighborhood Hits	480	Target Neighborhood Hits	872	Shared Neighborhood Hits	288
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

GLSL_MOUSE
NC score	0.443747 (rank : 242)	θ value	1.06291 (rank : 414)
Query Neighborhood Hits	480	Target Neighborhood Hits	212	Shared Neighborhood Hits	202
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

AN13A_HUMAN
NC score	0.441365 (rank : 243)	θ value	0.00175202 (rank : 334)
Query Neighborhood Hits	480	Target Neighborhood Hits	243	Shared Neighborhood Hits	227
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

NOTC4_HUMAN
NC score	0.440007 (rank : 244)	θ value	3.76295e-14 (rank : 61)
Query Neighborhood Hits	480	Target Neighborhood Hits	905	Shared Neighborhood Hits	292
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

GIT2_HUMAN
NC score	0.439356 (rank : 245)	θ value	0.00228821 (rank : 340)
Query Neighborhood Hits	480	Target Neighborhood Hits	381	Shared Neighborhood Hits	251
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

ABTB1_MOUSE
NC score	0.434413 (rank : 246)	θ value	0.00228821 (rank : 338)
Query Neighborhood Hits	480	Target Neighborhood Hits	349	Shared Neighborhood Hits	270
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

DDFL1_MOUSE
NC score	0.420851 (rank : 247)	θ value	0.00869519 (rank : 359)
Query Neighborhood Hits	480	Target Neighborhood Hits	324	Shared Neighborhood Hits	252
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

AN13A_MOUSE
NC score	0.419249 (rank : 248)	θ value	0.0252991 (rank : 368)
Query Neighborhood Hits	480	Target Neighborhood Hits	226	Shared Neighborhood Hits	216
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

TNI3K_HUMAN
NC score	0.411288 (rank : 249)	θ value	9.90251e-15 (rank : 50)
Query Neighborhood Hits	480	Target Neighborhood Hits	1084	Shared Neighborhood Hits	298
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

NOTC3_MOUSE
NC score	0.410356 (rank : 250)	θ value	6.20254e-17 (rank : 31)
Query Neighborhood Hits	480	Target Neighborhood Hits	975	Shared Neighborhood Hits	292
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

GLSK_HUMAN
NC score	0.410311 (rank : 251)	θ value	6.88961 (rank : 462)
Query Neighborhood Hits	480	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

CT012_MOUSE
NC score	0.410261 (rank : 252)	θ value	0.813845 (rank : 408)
Query Neighborhood Hits	480	Target Neighborhood Hits	229	Shared Neighborhood Hits	180
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

NOTC3_HUMAN
NC score	0.407885 (rank : 253)	θ value	8.10077e-17 (rank : 32)
Query Neighborhood Hits	480	Target Neighborhood Hits	1062	Shared Neighborhood Hits	290
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TNI3K_MOUSE
NC score	0.406721 (rank : 254)	θ value	8.95645e-16 (rank : 38)
Query Neighborhood Hits	480	Target Neighborhood Hits	1079	Shared Neighborhood Hits	298
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

NOTC1_HUMAN
NC score	0.405806 (rank : 255)	θ value	2.20605e-14 (rank : 57)
Query Neighborhood Hits	480	Target Neighborhood Hits	906	Shared Neighborhood Hits	285
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
NC score	0.403159 (rank : 256)	θ value	1.29331e-14 (rank : 53)
Query Neighborhood Hits	480	Target Neighborhood Hits	1113	Shared Neighborhood Hits	287
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
NC score	0.400538 (rank : 257)	θ value	1.68911e-14 (rank : 55)
Query Neighborhood Hits	480	Target Neighborhood Hits	1069	Shared Neighborhood Hits	284
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ABTB1_HUMAN
NC score	0.391752 (rank : 258)	θ value	3.0926 (rank : 441)
Query Neighborhood Hits	480	Target Neighborhood Hits	325	Shared Neighborhood Hits	252
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

CT012_HUMAN
NC score	0.381672 (rank : 259)	θ value	0.0961366 (rank : 382)
Query Neighborhood Hits	480	Target Neighborhood Hits	205	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DAPK1_MOUSE
NC score	0.375426 (rank : 260)	θ value	3.75424e-22 (rank : 22)
Query Neighborhood Hits	480	Target Neighborhood Hits	1138	Shared Neighborhood Hits	297
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_HUMAN
NC score	0.367377 (rank : 261)	θ value	7.82807e-20 (rank : 23)
Query Neighborhood Hits	480	Target Neighborhood Hits	1130	Shared Neighborhood Hits	292
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TEX14_HUMAN
NC score	0.366219 (rank : 262)	θ value	0.000121331 (rank : 294)
Query Neighborhood Hits	480	Target Neighborhood Hits	1103	Shared Neighborhood Hits	247
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
NC score	0.366102 (rank : 263)	θ value	0.000602161 (rank : 316)
Query Neighborhood Hits	480	Target Neighborhood Hits	1333	Shared Neighborhood Hits	269
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDEF2_HUMAN
NC score	0.351417 (rank : 264)	θ value	0.279714 (rank : 396)
Query Neighborhood Hits	480	Target Neighborhood Hits	599	Shared Neighborhood Hits	235
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DGKZ_HUMAN
NC score	0.349621 (rank : 265)	θ value	0.0113563 (rank : 361)
Query Neighborhood Hits	480	Target Neighborhood Hits	551	Shared Neighborhood Hits	222
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

NOTC1_MOUSE
NC score	0.349536 (rank : 266)	θ value	4.30538e-10 (rank : 121)
Query Neighborhood Hits	480	Target Neighborhood Hits	916	Shared Neighborhood Hits	261
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DDEF2_MOUSE
NC score	0.349362 (rank : 267)	θ value	0.279714 (rank : 397)
Query Neighborhood Hits	480	Target Neighborhood Hits	625	Shared Neighborhood Hits	239
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CENG1_MOUSE
NC score	0.342691 (rank : 268)	θ value	0.00134147 (rank : 332)
Query Neighborhood Hits	480	Target Neighborhood Hits	531	Shared Neighborhood Hits	242
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.341136 (rank : 269)	θ value	0.000602161 (rank : 314)
Query Neighborhood Hits	480	Target Neighborhood Hits	544	Shared Neighborhood Hits	242
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

DDFL1_HUMAN
NC score	0.337499 (rank : 270)	θ value	0.0563607 (rank : 378)
Query Neighborhood Hits	480	Target Neighborhood Hits	353	Shared Neighborhood Hits	229
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

CENG2_HUMAN
NC score	0.335952 (rank : 271)	θ value	0.00390308 (rank : 346)
Query Neighborhood Hits	480	Target Neighborhood Hits	471	Shared Neighborhood Hits	257
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

IKBL_HUMAN
NC score	0.334251 (rank : 272)	θ value	0.0961366 (rank : 384)
Query Neighborhood Hits	480	Target Neighborhood Hits	168	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CENG2_MOUSE
NC score	0.332119 (rank : 273)	θ value	0.0113563 (rank : 360)
Query Neighborhood Hits	480	Target Neighborhood Hits	463	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DGKZ_MOUSE
NC score	0.331333 (rank : 274)	θ value	0.0961366 (rank : 383)
Query Neighborhood Hits	480	Target Neighborhood Hits	542	Shared Neighborhood Hits	208
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

IKBL_MOUSE
NC score	0.326389 (rank : 275)	θ value	0.0961366 (rank : 385)
Query Neighborhood Hits	480	Target Neighborhood Hits	196	Shared Neighborhood Hits	139
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

DGKI_HUMAN
NC score	0.315935 (rank : 276)	θ value	0.813845 (rank : 409)
Query Neighborhood Hits	480	Target Neighborhood Hits	609	Shared Neighborhood Hits	222
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

CENG3_MOUSE
NC score	0.311296 (rank : 277)	θ value	0.00665767 (rank : 357)
Query Neighborhood Hits	480	Target Neighborhood Hits	467	Shared Neighborhood Hits	229
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.311072 (rank : 278)	θ value	0.00665767 (rank : 356)
Query Neighborhood Hits	480	Target Neighborhood Hits	455	Shared Neighborhood Hits	229
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ANKZ1_MOUSE
NC score	0.306217 (rank : 279)	θ value	1.06291 (rank : 413)
Query Neighborhood Hits	480	Target Neighborhood Hits	208	Shared Neighborhood Hits	152
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ZFY21_MOUSE
NC score	0.305960 (rank : 280)	θ value	1.63604e-09 (rank : 131)
Query Neighborhood Hits	480	Target Neighborhood Hits	72	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_HUMAN
NC score	0.305079 (rank : 281)	θ value	1.63604e-09 (rank : 130)
Query Neighborhood Hits	480	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
NC score	0.299942 (rank : 282)	θ value	5.62301e-10 (rank : 123)
Query Neighborhood Hits	480	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ANKZ1_HUMAN
NC score	0.298576 (rank : 283)	θ value	0.47712 (rank : 402)
Query Neighborhood Hits	480	Target Neighborhood Hits	236	Shared Neighborhood Hits	160
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

TRPV1_MOUSE
NC score	0.289945 (rank : 284)	θ value	1.87187e-05 (rank : 257)
Query Neighborhood Hits	480	Target Neighborhood Hits	189	Shared Neighborhood Hits	162
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV3_HUMAN
NC score	0.287731 (rank : 285)	θ value	4.1701e-05 (rank : 274)
Query Neighborhood Hits	480	Target Neighborhood Hits	198	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.287391 (rank : 286)	θ value	0.00175202 (rank : 337)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	138
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

CLR59_HUMAN
NC score	0.285045 (rank : 287)	θ value	0.0563607 (rank : 377)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	141
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

PKHF2_MOUSE
NC score	0.277581 (rank : 288)	θ value	1.06045e-08 (rank : 165)
Query Neighborhood Hits	480	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHF2_HUMAN
NC score	0.277392 (rank : 289)	θ value	1.06045e-08 (rank : 164)
Query Neighborhood Hits	480	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

ANKR9_MOUSE
NC score	0.274363 (rank : 290)	θ value	4.03905 (rank : 448)
Query Neighborhood Hits	480	Target Neighborhood Hits	120	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

PKHF1_HUMAN
NC score	0.272695 (rank : 291)	θ value	7.59969e-07 (rank : 211)
Query Neighborhood Hits	480	Target Neighborhood Hits	76	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

TRPV1_HUMAN
NC score	0.272069 (rank : 292)	θ value	0.00035302 (rank : 309)
Query Neighborhood Hits	480	Target Neighborhood Hits	184	Shared Neighborhood Hits	155
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

PKHF1_MOUSE
NC score	0.268772 (rank : 293)	θ value	1.69304e-06 (rank : 226)
Query Neighborhood Hits	480	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

DDEF1_MOUSE
NC score	0.265994 (rank : 294)	θ value	6.88961 (rank : 461)
Query Neighborhood Hits	480	Target Neighborhood Hits	592	Shared Neighborhood Hits	199
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

BAT4_MOUSE
NC score	0.259452 (rank : 295)	θ value	0.21417 (rank : 391)
Query Neighborhood Hits	480	Target Neighborhood Hits	171	Shared Neighborhood Hits	119
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

HGS_HUMAN
NC score	0.257139 (rank : 296)	θ value	4.44505e-15 (rank : 45)
Query Neighborhood Hits	480	Target Neighborhood Hits	517	Shared Neighborhood Hits	66
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

SPOP_HUMAN
NC score	0.256715 (rank : 297)	θ value	8.11959e-09 (rank : 160)
Query Neighborhood Hits	480	Target Neighborhood Hits	168	Shared Neighborhood Hits	102
SwissProt Accessions	O43791	Gene names	SPOP
Domain Architecture
Description	Speckle-type POZ protein.

SPOP_MOUSE
NC score	0.256715 (rank : 298)	θ value	8.11959e-09 (rank : 161)
Query Neighborhood Hits	480	Target Neighborhood Hits	168	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZWS8	Gene names	Spop, Pcif1
Domain Architecture	No domain graphic available
Description	Speckle-type POZ protein (PDX-1 C-terminal-interacting factor 1) (PCIF1).

ZFY16_MOUSE
NC score	0.256324 (rank : 299)	θ value	2.36244e-08 (rank : 170)
Query Neighborhood Hits	480	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

HGS_MOUSE
NC score	0.253932 (rank : 300)	θ value	3.40345e-15 (rank : 44)
Query Neighborhood Hits	480	Target Neighborhood Hits	589	Shared Neighborhood Hits	66
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

KBTB4_MOUSE
NC score	0.253731 (rank : 301)	θ value	8.97725e-08 (rank : 178)
Query Neighborhood Hits	480	Target Neighborhood Hits	182	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R179, Q9CQX1	Gene names	Kbtbd4, Bklhd4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

KBTB4_HUMAN
NC score	0.253455 (rank : 302)	θ value	1.99992e-07 (rank : 192)
Query Neighborhood Hits	480	Target Neighborhood Hits	187	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NVX7, Q6IA85, Q9BUC3, Q9NV76	Gene names	KBTBD4, BKLHD4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

ZFYV9_HUMAN
NC score	0.252957 (rank : 303)	θ value	3.77169e-06 (rank : 237)
Query Neighborhood Hits	480	Target Neighborhood Hits	134	Shared Neighborhood Hits	57
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

BTBD9_MOUSE
NC score	0.252662 (rank : 304)	θ value	4.92598e-06 (rank : 243)
Query Neighborhood Hits	480	Target Neighborhood Hits	165	Shared Neighborhood Hits	97
SwissProt Accessions	Q8C726	Gene names	Btbd9
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

ZFY16_HUMAN
NC score	0.252027 (rank : 305)	θ value	2.36244e-08 (rank : 169)
Query Neighborhood Hits	480	Target Neighborhood Hits	125	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

KLHL7_MOUSE
NC score	0.251299 (rank : 306)	θ value	8.67504e-11 (rank : 113)
Query Neighborhood Hits	480	Target Neighborhood Hits	179	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BUL5, Q9CZP4	Gene names	Klhl7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

KLHL7_HUMAN
NC score	0.251291 (rank : 307)	θ value	8.67504e-11 (rank : 112)
Query Neighborhood Hits	480	Target Neighborhood Hits	176	Shared Neighborhood Hits	99
SwissProt Accessions	Q8IXQ5, Q9BQF8	Gene names	KLHL7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

BTBD9_HUMAN
NC score	0.250936 (rank : 308)	θ value	4.1701e-05 (rank : 271)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	99
SwissProt Accessions	Q96Q07, Q96M00	Gene names	BTBD9, KIAA1880
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

TRPV2_HUMAN
NC score	0.250869 (rank : 309)	θ value	0.163984 (rank : 389)
Query Neighborhood Hits	480	Target Neighborhood Hits	130	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

KBTB3_HUMAN
NC score	0.250274 (rank : 310)	θ value	6.21693e-09 (rank : 150)
Query Neighborhood Hits	480	Target Neighborhood Hits	176	Shared Neighborhood Hits	101
SwissProt Accessions	Q8NAB2, Q86X38, Q96NK5	Gene names	KBTBD3, BKLHD3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KBTBA_HUMAN
NC score	0.249239 (rank : 311)	θ value	6.21693e-09 (rank : 151)
Query Neighborhood Hits	480	Target Neighborhood Hits	184	Shared Neighborhood Hits	98
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

KBTB2_HUMAN
NC score	0.247346 (rank : 312)	θ value	1.99992e-07 (rank : 191)
Query Neighborhood Hits	480	Target Neighborhood Hits	179	Shared Neighborhood Hits	104
SwissProt Accessions	Q8IY47, Q86Y62, Q9P239, Q9UFM7	Gene names	KBTBD2, BKLHD1, KIAA1489
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1).

KBTB3_MOUSE
NC score	0.245628 (rank : 313)	θ value	9.92553e-07 (rank : 215)
Query Neighborhood Hits	480	Target Neighborhood Hits	176	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BHI4, Q8BNJ8	Gene names	Kbtbd3, Bklhd3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KLHL8_MOUSE
NC score	0.243576 (rank : 314)	θ value	5.62301e-10 (rank : 122)
Query Neighborhood Hits	480	Target Neighborhood Hits	183	Shared Neighborhood Hits	104
SwissProt Accessions	P59280	Gene names	Klhl8
Domain Architecture
Description	Kelch-like protein 8.

KLHL8_HUMAN
NC score	0.242391 (rank : 315)	θ value	6.21693e-09 (rank : 152)
Query Neighborhood Hits	480	Target Neighborhood Hits	180	Shared Neighborhood Hits	104
SwissProt Accessions	Q9P2G9	Gene names	KLHL8, KIAA1378
Domain Architecture
Description	Kelch-like protein 8.

BTBD1_HUMAN
NC score	0.239487 (rank : 316)	θ value	9.92553e-07 (rank : 213)
Query Neighborhood Hits	480	Target Neighborhood Hits	127	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H0C5, Q9BX71, Q9NWN4	Gene names	BTBD1, C15orf1
Domain Architecture
Description	BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A- transactivated protein 8) (NS5ATP8).

ZFYV1_MOUSE
NC score	0.236814 (rank : 317)	θ value	3.77169e-06 (rank : 236)
Query Neighborhood Hits	480	Target Neighborhood Hits	153	Shared Neighborhood Hits	56
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

TDPZ4_MOUSE
NC score	0.235114 (rank : 318)	θ value	2.44474e-05 (rank : 263)
Query Neighborhood Hits	480	Target Neighborhood Hits	162	Shared Neighborhood Hits	101
SwissProt Accessions	Q6YCH2	Gene names	Tdpoz4
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 4.

ZFYV1_HUMAN
NC score	0.234881 (rank : 319)	θ value	1.87187e-05 (rank : 258)
Query Neighborhood Hits	480	Target Neighborhood Hits	166	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

KLHL6_MOUSE
NC score	0.234566 (rank : 320)	θ value	5.44631e-05 (rank : 282)
Query Neighborhood Hits	480	Target Neighborhood Hits	186	Shared Neighborhood Hits	99
SwissProt Accessions	Q6V595	Gene names	Klhl6
Domain Architecture	No domain graphic available
Description	Kelch-like protein 6.

KLHL6_HUMAN
NC score	0.233724 (rank : 321)	θ value	0.00035302 (rank : 308)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WZ60, Q8N5I1, Q8N892	Gene names	KLHL6
Domain Architecture
Description	Kelch-like protein 6.

KLHL3_HUMAN
NC score	0.233021 (rank : 322)	θ value	1.53129e-07 (rank : 185)
Query Neighborhood Hits	480	Target Neighborhood Hits	187	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UH77, Q9UH75, Q9UH76, Q9ULU0, Q9Y6V6	Gene names	KLHL3, KIAA1129
Domain Architecture
Description	Kelch-like protein 3.

KLHL5_HUMAN
NC score	0.231871 (rank : 323)	θ value	1.38499e-08 (rank : 166)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	104
SwissProt Accessions	Q96PQ7, Q86XW0, Q9NUK3, Q9NV27, Q9NVA9, Q9Y2X2	Gene names	KLHL5
Domain Architecture
Description	Kelch-like protein 5.

KLH17_HUMAN
NC score	0.231480 (rank : 324)	θ value	4.45536e-07 (rank : 206)
Query Neighborhood Hits	480	Target Neighborhood Hits	201	Shared Neighborhood Hits	104
SwissProt Accessions	Q6TDP4	Gene names	KLHL17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

KLH17_MOUSE
NC score	0.231071 (rank : 325)	θ value	4.45536e-07 (rank : 207)
Query Neighborhood Hits	480	Target Neighborhood Hits	200	Shared Neighborhood Hits	103
SwissProt Accessions	Q6TDP3	Gene names	Klhl17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

BTBD5_MOUSE
NC score	0.230993 (rank : 326)	θ value	2.88788e-06 (rank : 232)
Query Neighborhood Hits	480	Target Neighborhood Hits	189	Shared Neighborhood Hits	104
SwissProt Accessions	Q9CR40, Q9CYV0	Gene names	Btbd5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

BTBD5_HUMAN
NC score	0.229733 (rank : 327)	θ value	6.43352e-06 (rank : 245)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NXS3	Gene names	BTBD5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

KLHL1_MOUSE
NC score	0.229494 (rank : 328)	θ value	8.11959e-09 (rank : 158)
Query Neighborhood Hits	480	Target Neighborhood Hits	193	Shared Neighborhood Hits	100
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

KLHL2_HUMAN
NC score	0.229493 (rank : 329)	θ value	4.92598e-06 (rank : 244)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	O95198, Q8N484, Q8TBH5	Gene names	KLHL2
Domain Architecture
Description	Kelch-like protein 2 (Actin-binding protein Mayven).

KLH23_HUMAN
NC score	0.229268 (rank : 330)	θ value	0.00298849 (rank : 342)
Query Neighborhood Hits	480	Target Neighborhood Hits	198	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

ENC1_HUMAN
NC score	0.229027 (rank : 331)	θ value	5.44631e-05 (rank : 278)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	100
SwissProt Accessions	O14682, O75464, Q9UPG9	Gene names	ENC1, NRPB, PIG10
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1) (p53-induced protein 10) (Nuclear matrix protein NRP/B).

KLHL1_HUMAN
NC score	0.229024 (rank : 332)	θ value	8.11959e-09 (rank : 157)
Query Neighborhood Hits	480	Target Neighborhood Hits	195	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NR64, Q5VZ64, Q9H4X4, Q9NR65, Q9P238	Gene names	KLHL1, KIAA1490
Domain Architecture
Description	Kelch-like protein 1.

KLHL4_HUMAN
NC score	0.229001 (rank : 333)	θ value	9.92553e-07 (rank : 217)
Query Neighborhood Hits	480	Target Neighborhood Hits	212	Shared Neighborhood Hits	102
SwissProt Accessions	Q9C0H6, Q9Y3J5	Gene names	KLHL4, KIAA1687
Domain Architecture
Description	Kelch-like protein 4.

ENC1_MOUSE
NC score	0.228918 (rank : 334)	θ value	5.44631e-05 (rank : 279)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	100
SwissProt Accessions	O35709	Gene names	Enc1, Enc-1
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1).

KLHL2_MOUSE
NC score	0.228483 (rank : 335)	θ value	2.44474e-05 (rank : 262)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	104
SwissProt Accessions	Q8JZP3, Q8CCU0, Q8R3U4	Gene names	Klhl2
Domain Architecture	No domain graphic available
Description	Kelch-like protein 2.

ANKR9_HUMAN
NC score	0.228286 (rank : 336)	θ value	4.03905 (rank : 447)
Query Neighborhood Hits	480	Target Neighborhood Hits	99	Shared Neighborhood Hits	98
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

KLH12_HUMAN
NC score	0.227857 (rank : 337)	θ value	9.92553e-07 (rank : 216)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	103
SwissProt Accessions	Q53G59, Q9HBX5	Gene names	KLHL12, C3IP1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

IPP_HUMAN
NC score	0.227764 (rank : 338)	θ value	4.45536e-07 (rank : 205)
Query Neighborhood Hits	480	Target Neighborhood Hits	186	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y573	Gene names	IPP
Domain Architecture
Description	Actin-binding protein IPP (MIPP protein).

TDPZ1_MOUSE
NC score	0.227519 (rank : 339)	θ value	0.00134147 (rank : 333)
Query Neighborhood Hits	480	Target Neighborhood Hits	164	Shared Neighborhood Hits	100
SwissProt Accessions	Q717B3, Q71G58, Q8BZV7, Q8VI39	Gene names	Tdpoz1, 2cpoz56, Mapp2, Spopl1
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 1 (MAPP family protein 2).

KLH12_MOUSE
NC score	0.227478 (rank : 340)	θ value	2.21117e-06 (rank : 228)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BZM0, Q8K225	Gene names	Klhl12, C3ip1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

TDPZ2_MOUSE
NC score	0.227412 (rank : 341)	θ value	0.00102713 (rank : 331)
Query Neighborhood Hits	480	Target Neighborhood Hits	162	Shared Neighborhood Hits	103
SwissProt Accessions	Q717B2	Gene names	Tdpoz2
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 2.

KLH21_HUMAN
NC score	0.227279 (rank : 342)	θ value	0.000270298 (rank : 304)
Query Neighborhood Hits	480	Target Neighborhood Hits	173	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UJP4, O75057	Gene names	KLHL21, KIAA0469
Domain Architecture
Description	Kelch-like protein 21.

KLH23_MOUSE
NC score	0.227233 (rank : 343)	θ value	0.000786445 (rank : 321)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	101
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

RSNL2_HUMAN
NC score	0.226831 (rank : 344)	θ value	0.47712 (rank : 405)
Query Neighborhood Hits	480	Target Neighborhood Hits	136	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TDPZ5_MOUSE
NC score	0.226823 (rank : 345)	θ value	9.29e-05 (rank : 291)
Query Neighborhood Hits	480	Target Neighborhood Hits	160	Shared Neighborhood Hits	98
SwissProt Accessions	Q6YCH1	Gene names	Tdpoz5
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 5.

GAN_HUMAN
NC score	0.226755 (rank : 346)	θ value	0.00175202 (rank : 336)
Query Neighborhood Hits	480	Target Neighborhood Hits	180	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2C0	Gene names	GAN, GAN1, KLHL16
Domain Architecture
Description	Gigaxonin (Kelch-like protein 16).

TDPZ3_MOUSE
NC score	0.226160 (rank : 347)	θ value	0.00390308 (rank : 349)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	102
SwissProt Accessions	Q717B4	Gene names	Tdpoz3
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 3.

KLH11_HUMAN
NC score	0.225468 (rank : 348)	θ value	0.000786445 (rank : 320)
Query Neighborhood Hits	480	Target Neighborhood Hits	183	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NVR0	Gene names	KLHL11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

KLH11_MOUSE
NC score	0.225200 (rank : 349)	θ value	0.00102713 (rank : 329)
Query Neighborhood Hits	480	Target Neighborhood Hits	177	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CE33, Q3TDZ6, Q91VP6	Gene names	Klhl11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

IPP_MOUSE
NC score	0.224915 (rank : 350)	θ value	0.00020696 (rank : 297)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	104
SwissProt Accessions	P28575	Gene names	Ipp, Mipp
Domain Architecture
Description	Actin-binding protein IPP (MIPP protein) (Murine IAP-promoted placenta-expressed protein).

BTBD2_HUMAN
NC score	0.224240 (rank : 351)	θ value	4.92598e-06 (rank : 242)
Query Neighborhood Hits	480	Target Neighborhood Hits	161	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

BTBD1_MOUSE
NC score	0.223336 (rank : 352)	θ value	2.44474e-05 (rank : 260)
Query Neighborhood Hits	480	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	P58544, Q8BTZ0, Q8K0J0	Gene names	Btbd1, Gsrp
Domain Architecture
Description	BTB/POZ domain-containing protein 1 (Glucose signal repressing protein).

KLH10_HUMAN
NC score	0.223172 (rank : 353)	θ value	0.0113563 (rank : 363)
Query Neighborhood Hits	480	Target Neighborhood Hits	194	Shared Neighborhood Hits	104
SwissProt Accessions	Q6JEL2, Q6NW28, Q96MC0	Gene names	KLHL10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

BAT4_HUMAN
NC score	0.221535 (rank : 354)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	480	Target Neighborhood Hits	157	Shared Neighborhood Hits	109
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BTBD6_MOUSE
NC score	0.221444 (rank : 355)	θ value	1.43324e-05 (rank : 253)
Query Neighborhood Hits	480	Target Neighborhood Hits	125	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K2J9	Gene names	Btbd6
Domain Architecture
Description	BTB/POZ domain-containing protein 6.

BTBD3_HUMAN
NC score	0.218815 (rank : 356)	θ value	0.00102713 (rank : 326)
Query Neighborhood Hits	480	Target Neighborhood Hits	127	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y2F9	Gene names	BTBD3, KIAA0952
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

BTBD3_MOUSE
NC score	0.217332 (rank : 357)	θ value	0.00102713 (rank : 327)
Query Neighborhood Hits	480	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	P58545	Gene names	Btbd3
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

KBTB6_HUMAN
NC score	0.217246 (rank : 358)	θ value	0.0736092 (rank : 381)
Query Neighborhood Hits	480	Target Neighborhood Hits	175	Shared Neighborhood Hits	101
SwissProt Accessions	Q86V97, Q8N8L0, Q8NDM5, Q96MP6	Gene names	KBTBD6
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 6.

KLH22_HUMAN
NC score	0.217061 (rank : 359)	θ value	0.000270298 (rank : 305)
Query Neighborhood Hits	480	Target Neighborhood Hits	198	Shared Neighborhood Hits	104
SwissProt Accessions	Q53GT1, Q96B68, Q96KC6	Gene names	KLHL22
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

CALI_HUMAN
NC score	0.216509 (rank : 360)	θ value	0.0252991 (rank : 369)
Query Neighborhood Hits	480	Target Neighborhood Hits	183	Shared Neighborhood Hits	98
SwissProt Accessions	Q13939, Q9BXG7	Gene names	CCIN
Domain Architecture
Description	Calicin.

KBTB7_HUMAN
NC score	0.215663 (rank : 361)	θ value	0.279714 (rank : 398)
Query Neighborhood Hits	480	Target Neighborhood Hits	183	Shared Neighborhood Hits	102
SwissProt Accessions	Q8WVZ9, Q8NB99, Q9H0I6	Gene names	KBTBD7
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 7.

KBTB9_MOUSE
NC score	0.215534 (rank : 362)	θ value	0.0113563 (rank : 362)
Query Neighborhood Hits	480	Target Neighborhood Hits	197	Shared Neighborhood Hits	100
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KLH22_MOUSE
NC score	0.214558 (rank : 363)	θ value	0.00509761 (rank : 354)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	105
SwissProt Accessions	Q99JN2, Q8BT13	Gene names	Klhl22, Kelchl
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

KBTB9_HUMAN
NC score	0.214295 (rank : 364)	θ value	0.0563607 (rank : 379)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	100
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KLH20_MOUSE
NC score	0.214177 (rank : 365)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	102
SwissProt Accessions	Q8VCK5, Q8BWA2	Gene names	Klhl20, Kleip
Domain Architecture	No domain graphic available
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein).

KLH20_HUMAN
NC score	0.214150 (rank : 366)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y2M5, Q5TZF2, Q9H457	Gene names	KLHL20, KLEIP
Domain Architecture
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch- like protein X).

KLH10_MOUSE
NC score	0.213606 (rank : 367)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	480	Target Neighborhood Hits	192	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D5V2, Q8BVM3, Q9DA07	Gene names	Klhl10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KEAP1_HUMAN
NC score	0.213344 (rank : 368)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	480	Target Neighborhood Hits	181	Shared Neighborhood Hits	101
SwissProt Accessions	Q14145, Q6LEP0	Gene names	KEAP1, KIAA0132, KLHL19
Domain Architecture	No domain graphic available
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (Kelch-like protein 19).

FGD5_MOUSE
NC score	0.212778 (rank : 369)	θ value	1.99992e-07 (rank : 188)
Query Neighborhood Hits	480	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

KEAP1_MOUSE
NC score	0.212751 (rank : 370)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	480	Target Neighborhood Hits	182	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z2X8	Gene names	Keap1
Domain Architecture
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2).

LZTR1_HUMAN
NC score	0.211275 (rank : 371)	θ value	1.29631e-06 (rank : 221)
Query Neighborhood Hits	480	Target Neighborhood Hits	196	Shared Neighborhood Hits	100
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

KLH18_HUMAN
NC score	0.210174 (rank : 372)	θ value	0.0431538 (rank : 376)
Query Neighborhood Hits	480	Target Neighborhood Hits	143	Shared Neighborhood Hits	75
SwissProt Accessions	O94889, Q8N125	Gene names	KLHL18, KIAA0795
Domain Architecture
Description	Kelch-like protein 18.

FGD6_HUMAN
NC score	0.209204 (rank : 373)	θ value	8.11959e-09 (rank : 155)
Query Neighborhood Hits	480	Target Neighborhood Hits	237	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

BKLH5_HUMAN
NC score	0.208500 (rank : 374)	θ value	0.00869519 (rank : 358)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	104
SwissProt Accessions	Q96NJ5, Q96PY7	Gene names	BKLHD5, KIAA1900
Domain Architecture
Description	BTB and kelch domain-containing protein 5.

KLH26_MOUSE
NC score	0.207850 (rank : 375)	θ value	0.0113563 (rank : 364)
Query Neighborhood Hits	480	Target Neighborhood Hits	190	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BGY4, Q8CIG6, Q8R153	Gene names	Klhl26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

FGD5_HUMAN
NC score	0.207259 (rank : 376)	θ value	9.92553e-07 (rank : 214)
Query Neighborhood Hits	480	Target Neighborhood Hits	235	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

KLH26_HUMAN
NC score	0.207151 (rank : 377)	θ value	0.00509761 (rank : 355)
Query Neighborhood Hits	480	Target Neighborhood Hits	188	Shared Neighborhood Hits	101
SwissProt Accessions	Q53HC5, Q8TAP0, Q9NUX3	Gene names	KLHL26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

LZTR1_MOUSE
NC score	0.206714 (rank : 378)	θ value	6.43352e-06 (rank : 246)
Query Neighborhood Hits	480	Target Neighborhood Hits	200	Shared Neighborhood Hits	101
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

ZFY19_MOUSE
NC score	0.206564 (rank : 379)	θ value	0.000602161 (rank : 317)
Query Neighborhood Hits	480	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

FYV1_MOUSE
NC score	0.205967 (rank : 380)	θ value	4.45536e-07 (rank : 204)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.205671 (rank : 381)	θ value	4.45536e-07 (rank : 203)
Query Neighborhood Hits	480	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

ZFY19_HUMAN
NC score	0.205001 (rank : 382)	θ value	0.00020696 (rank : 300)
Query Neighborhood Hits	480	Target Neighborhood Hits	206	Shared Neighborhood Hits	53
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

KHL15_HUMAN
NC score	0.201559 (rank : 383)	θ value	1.06291 (rank : 415)
Query Neighborhood Hits	480	Target Neighborhood Hits	191	Shared Neighborhood Hits	102
SwissProt Accessions	Q96M94, Q32MN3, Q8NDA3, Q96BM6, Q9C0I6	Gene names	KLHL15, KIAA1677
Domain Architecture	No domain graphic available
Description	Kelch-like protein 15.

TRPV2_MOUSE
NC score	0.201276 (rank : 384)	θ value	3.0926 (rank : 442)
Query Neighborhood Hits	480	Target Neighborhood Hits	111	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

FGD6_MOUSE
NC score	0.200299 (rank : 385)	θ value	1.29631e-06 (rank : 220)
Query Neighborhood Hits	480	Target Neighborhood Hits	282	Shared Neighborhood Hits	56
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

RBNS5_HUMAN
NC score	0.194927 (rank : 386)	θ value	0.000270298 (rank : 306)
Query Neighborhood Hits	480	Target Neighborhood Hits	242	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

KLH13_MOUSE
NC score	0.193651 (rank : 387)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	480	Target Neighborhood Hits	193	Shared Neighborhood Hits	102
SwissProt Accessions	Q80TF4, Q9DBY7	Gene names	Klhl13, Bklhd2, Kiaa1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLH13_HUMAN
NC score	0.193379 (rank : 388)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	480	Target Neighborhood Hits	193	Shared Neighborhood Hits	102
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

RBNS5_MOUSE
NC score	0.192995 (rank : 389)	θ value	0.000270298 (rank : 307)
Query Neighborhood Hits	480	Target Neighborhood Hits	266	Shared Neighborhood Hits	52
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

KLHL9_MOUSE
NC score	0.192672 (rank : 390)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	480	Target Neighborhood Hits	195	Shared Neighborhood Hits	101
SwissProt Accessions	Q6ZPT1	Gene names	Klhl9, Kiaa1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

BTBD6_HUMAN
NC score	0.192510 (rank : 391)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	480	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	Q96KE9, Q8IVQ7, Q9BR94	Gene names	BTBD6, BDPL
Domain Architecture
Description	BTB/POZ domain-containing protein 6 (Lens BTB domain protein).

KLHL9_HUMAN
NC score	0.192430 (rank : 392)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	480	Target Neighborhood Hits	194	Shared Neighborhood Hits	101
SwissProt Accessions	Q9P2J3, Q8TCQ2	Gene names	KLHL9, KIAA1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

RUFY2_MOUSE
NC score	0.191517 (rank : 393)	θ value	2.79066e-09 (rank : 140)
Query Neighborhood Hits	480	Target Neighborhood Hits	820	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

FGD2_MOUSE
NC score	0.189206 (rank : 394)	θ value	2.61198e-07 (rank : 196)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

BTBD8_HUMAN
NC score	0.188460 (rank : 395)	θ value	6.88961 (rank : 459)
Query Neighborhood Hits	480	Target Neighborhood Hits	146	Shared Neighborhood Hits	88
SwissProt Accessions	Q5XKL5, Q6V9S5	Gene names	BTBD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 8.

RUFY1_HUMAN
NC score	0.188304 (rank : 396)	θ value	1.25267e-09 (rank : 127)
Query Neighborhood Hits	480	Target Neighborhood Hits	848	Shared Neighborhood Hits	81
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

KBTBB_MOUSE
NC score	0.187890 (rank : 397)	θ value	0.0252991 (rank : 372)
Query Neighborhood Hits	480	Target Neighborhood Hits	184	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BNW9	Gene names	Kbtbd11, Kiaa0711
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 11.

RCBT1_MOUSE
NC score	0.187751 (rank : 398)	θ value	1.09739e-05 (rank : 252)
Query Neighborhood Hits	480	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

RCBT1_HUMAN
NC score	0.187510 (rank : 399)	θ value	1.09739e-05 (rank : 251)
Query Neighborhood Hits	480	Target Neighborhood Hits	158	Shared Neighborhood Hits	92
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

FGD2_HUMAN
NC score	0.186005 (rank : 400)	θ value	2.21117e-06 (rank : 227)
Query Neighborhood Hits	480	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

KLH14_HUMAN
NC score	0.185944 (rank : 401)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	480	Target Neighborhood Hits	194	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2G3	Gene names	KLHL14, KIAA1384
Domain Architecture	No domain graphic available
Description	Kelch-like protein 14.

RSNL2_MOUSE
NC score	0.185039 (rank : 402)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	480	Target Neighborhood Hits	129	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RUFY1_MOUSE
NC score	0.184248 (rank : 403)	θ value	2.13673e-09 (rank : 135)
Query Neighborhood Hits	480	Target Neighborhood Hits	765	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

KBTBB_HUMAN
NC score	0.184022 (rank : 404)	θ value	0.0252991 (rank : 371)
Query Neighborhood Hits	480	Target Neighborhood Hits	195	Shared Neighborhood Hits	86
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

WDFY1_HUMAN
NC score	0.178625 (rank : 405)	θ value	1.53129e-07 (rank : 186)
Query Neighborhood Hits	480	Target Neighborhood Hits	305	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

WDFY2_MOUSE
NC score	0.177432 (rank : 406)	θ value	5.26297e-08 (rank : 177)
Query Neighborhood Hits	480	Target Neighborhood Hits	337	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY2_HUMAN
NC score	0.176132 (rank : 407)	θ value	5.26297e-08 (rank : 176)
Query Neighborhood Hits	480	Target Neighborhood Hits	332	Shared Neighborhood Hits	50
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

FGD4_MOUSE
NC score	0.176002 (rank : 408)	θ value	5.44631e-05 (rank : 280)
Query Neighborhood Hits	480	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD1_HUMAN
NC score	0.175006 (rank : 409)	θ value	2.44474e-05 (rank : 261)
Query Neighborhood Hits	480	Target Neighborhood Hits	367	Shared Neighborhood Hits	64
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ZFY27_HUMAN
NC score	0.174759 (rank : 410)	θ value	0.000602161 (rank : 318)
Query Neighborhood Hits	480	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

FGD4_HUMAN
NC score	0.174748 (rank : 411)	θ value	4.1701e-05 (rank : 272)
Query Neighborhood Hits	480	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

ZFY27_MOUSE
NC score	0.174003 (rank : 412)	θ value	0.000786445 (rank : 322)
Query Neighborhood Hits	480	Target Neighborhood Hits	53	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TXX3, Q8CFP8	Gene names	Zfyve27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

FGD1_MOUSE
NC score	0.173901 (rank : 413)	θ value	1.87187e-05 (rank : 256)
Query Neighborhood Hits	480	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

WDFY3_MOUSE
NC score	0.172434 (rank : 414)	θ value	1.47974e-10 (rank : 117)
Query Neighborhood Hits	480	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

WDFY3_HUMAN
NC score	0.171853 (rank : 415)	θ value	1.47974e-10 (rank : 116)
Query Neighborhood Hits	480	Target Neighborhood Hits	348	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

MTMR3_HUMAN
NC score	0.171052 (rank : 416)	θ value	1.25267e-09 (rank : 126)
Query Neighborhood Hits	480	Target Neighborhood Hits	163	Shared Neighborhood Hits	56
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

TRPV4_HUMAN
NC score	0.166839 (rank : 417)	θ value	1.81305 (rank : 434)
Query Neighborhood Hits	480	Target Neighborhood Hits	150	Shared Neighborhood Hits	88
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CMTA1_HUMAN
NC score	0.165673 (rank : 418)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	480	Target Neighborhood Hits	217	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

RCBT2_MOUSE
NC score	0.163983 (rank : 419)	θ value	7.1131e-05 (rank : 287)
Query Neighborhood Hits	480	Target Neighborhood Hits	156	Shared Neighborhood Hits	83
SwissProt Accessions	Q99LJ7, Q3TUA3, Q8BMG2	Gene names	Rcbtb2, Chc1l
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like).

KLDC5_HUMAN
NC score	0.162164 (rank : 420)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	480	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P2K6, Q2VPK1, Q8N334	Gene names	KLHDC5, KIAA1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

RCBT2_HUMAN
NC score	0.161445 (rank : 421)	θ value	5.44631e-05 (rank : 284)
Query Neighborhood Hits	480	Target Neighborhood Hits	158	Shared Neighborhood Hits	81
SwissProt Accessions	O95199	Gene names	RCBTB2, CHC1L, RLG
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 2 (Regulator of chromosome condensation and BTB domain-containing protein 2) (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor).

FGD3_HUMAN
NC score	0.161248 (rank : 422)	θ value	0.000461057 (rank : 311)
Query Neighborhood Hits	480	Target Neighborhood Hits	249	Shared Neighborhood Hits	58
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

KLDC5_MOUSE
NC score	0.159855 (rank : 423)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	480	Target Neighborhood Hits	86	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BFQ9, Q6ZPT4	Gene names	Klhdc5, Kiaa1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

RUFY2_HUMAN
NC score	0.158637 (rank : 424)	θ value	8.11959e-09 (rank : 159)
Query Neighborhood Hits	480	Target Neighborhood Hits	1208	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

TRPV4_MOUSE
NC score	0.156590 (rank : 425)	θ value	1.81305 (rank : 435)
Query Neighborhood Hits	480	Target Neighborhood Hits	117	Shared Neighborhood Hits	85
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

KLD7B_HUMAN
NC score	0.155389 (rank : 426)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	480	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q96G42	Gene names	KLHDC7B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 7B.

KLD8A_MOUSE
NC score	0.149267 (rank : 427)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	480	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XA8	Gene names	Klhdc8a
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLD8A_HUMAN
NC score	0.148717 (rank : 428)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	480	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IYD2, Q9NVG5	Gene names	KLHDC8A
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

GMCL1_MOUSE
NC score	0.147649 (rank : 429)	θ value	0.0736092 (rank : 380)
Query Neighborhood Hits	480	Target Neighborhood Hits	87	Shared Neighborhood Hits	65
SwissProt Accessions	Q920G9, Q9DBW5, Q9QUP6	Gene names	Gmcl1, Gcl, Gcl1
Domain Architecture
Description	Germ cell-less protein-like 1 (mGcl-1) (DP-interacting protein) (DIP).

GMCL1_HUMAN
NC score	0.147345 (rank : 430)	θ value	0.0252991 (rank : 370)
Query Neighborhood Hits	480	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	Q96IK5, Q9H826, Q9H8V7, Q9H927	Gene names	GMCL1, GCL
Domain Architecture
Description	Germ cell-less protein-like 1.

FGD3_MOUSE
NC score	0.144201 (rank : 431)	θ value	0.00509761 (rank : 353)
Query Neighborhood Hits	480	Target Neighborhood Hits	257	Shared Neighborhood Hits	57
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

KLD8B_MOUSE
NC score	0.140585 (rank : 432)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	480	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D2D9	Gene names	Klhdc8b
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLD8B_HUMAN
NC score	0.139924 (rank : 433)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	480	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IXV7	Gene names	KLHDC8B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

ANKF1_HUMAN
NC score	0.138910 (rank : 434)	θ value	6.88961 (rank : 458)
Query Neighborhood Hits	480	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

GMCLL_HUMAN
NC score	0.138778 (rank : 435)	θ value	0.365318 (rank : 401)
Query Neighborhood Hits	480	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NEA9, Q8TC88, Q8TC89	Gene names	GMCL1L, GCL
Domain Architecture
Description	Germ cell-less protein-like 1-like.

RHBT3_MOUSE
NC score	0.135680 (rank : 436)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	480	Target Neighborhood Hits	120	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CTN4, Q80X55, Q9CVT0	Gene names	Rhobtb3, Kiaa0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

RHBT3_HUMAN
NC score	0.135510 (rank : 437)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	480	Target Neighborhood Hits	116	Shared Neighborhood Hits	71
SwissProt Accessions	O94955, Q8IW06	Gene names	RHOBTB3, KIAA0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

FYCO1_HUMAN
NC score	0.135332 (rank : 438)	θ value	1.43324e-05 (rank : 255)
Query Neighborhood Hits	480	Target Neighborhood Hits	1149	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

EEA1_MOUSE
NC score	0.129571 (rank : 439)	θ value	1.63604e-09 (rank : 128)
Query Neighborhood Hits	480	Target Neighborhood Hits	1637	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CMTA2_HUMAN
NC score	0.129320 (rank : 440)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	480	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CU081_HUMAN
NC score	0.128056 (rank : 441)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	480	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

EEA1_HUMAN
NC score	0.123875 (rank : 442)	θ value	6.21693e-09 (rank : 149)
Query Neighborhood Hits	480	Target Neighborhood Hits	1796	Shared Neighborhood Hits	109
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

BACH2_HUMAN
NC score	0.123480 (rank : 443)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	480	Target Neighborhood Hits	234	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

FYCO1_MOUSE
NC score	0.123168 (rank : 444)	θ value	4.1701e-05 (rank : 273)
Query Neighborhood Hits	480	Target Neighborhood Hits	1059	Shared Neighborhood Hits	84
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

CMTA2_MOUSE
NC score	0.121594 (rank : 445)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	480	Target Neighborhood Hits	216	Shared Neighborhood Hits	74
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

BACH1_MOUSE
NC score	0.118900 (rank : 446)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

BACH1_HUMAN
NC score	0.118610 (rank : 447)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	480	Target Neighborhood Hits	289	Shared Neighborhood Hits	97
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH2_MOUSE
NC score	0.118002 (rank : 448)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	480	Target Neighborhood Hits	248	Shared Neighborhood Hits	93
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

TRPC6_HUMAN
NC score	0.112594 (rank : 449)	θ value	0.62314 (rank : 407)
Query Neighborhood Hits	480	Target Neighborhood Hits	171	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

BTBD7_MOUSE
NC score	0.100980 (rank : 450)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	480	Target Neighborhood Hits	228	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

BTBD7_HUMAN
NC score	0.094900 (rank : 451)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	480	Target Neighborhood Hits	176	Shared Neighborhood Hits	79
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

TRPC3_HUMAN
NC score	0.091506 (rank : 452)	θ value	1.81305 (rank : 430)
Query Neighborhood Hits	480	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
NC score	0.088173 (rank : 453)	θ value	1.81305 (rank : 433)
Query Neighborhood Hits	480	Target Neighborhood Hits	171	Shared Neighborhood Hits	97
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

KLDC3_MOUSE
NC score	0.085489 (rank : 454)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	480	Target Neighborhood Hits	77	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VEM9, Q3TCN9, Q3UR95, Q91XU6, Q99JH9, Q9DBG8	Gene names	Klhdc3, Peas
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

TRPC3_MOUSE
NC score	0.084062 (rank : 455)	θ value	2.36792 (rank : 438)
Query Neighborhood Hits	480	Target Neighborhood Hits	131	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC7_MOUSE
NC score	0.079887 (rank : 456)	θ value	5.27518 (rank : 454)
Query Neighborhood Hits	480	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.079777 (rank : 457)	θ value	5.27518 (rank : 453)
Query Neighborhood Hits	480	Target Neighborhood Hits	123	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

RFFL_MOUSE
NC score	0.078358 (rank : 458)	θ value	1.06291 (rank : 416)
Query Neighborhood Hits	480	Target Neighborhood Hits	145	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

TRPC5_MOUSE
NC score	0.077715 (rank : 459)	θ value	1.81305 (rank : 432)
Query Neighborhood Hits	480	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

KLDC3_HUMAN
NC score	0.077282 (rank : 460)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	480	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BQ90	Gene names	KLHDC3, PEAS
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

TRPC5_HUMAN
NC score	0.076380 (rank : 461)	θ value	1.81305 (rank : 431)
Query Neighborhood Hits	480	Target Neighborhood Hits	122	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

ZBT25_HUMAN
NC score	0.075035 (rank : 462)	θ value	1.06291 (rank : 417)
Query Neighborhood Hits	480	Target Neighborhood Hits	644	Shared Neighborhood Hits	83
SwissProt Accessions	P24278, Q8IYH9	Gene names	ZBTB25, KUP, ZNF46
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP).

TRPC4_MOUSE
NC score	0.074166 (rank : 463)	θ value	4.03905 (rank : 451)
Query Neighborhood Hits	480	Target Neighborhood Hits	141	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

RNF34_MOUSE
NC score	0.074066 (rank : 464)	θ value	8.99809 (rank : 477)
Query Neighborhood Hits	480	Target Neighborhood Hits	160	Shared Neighborhood Hits	39
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

TRPC4_HUMAN
NC score	0.074033 (rank : 465)	θ value	4.03905 (rank : 450)
Query Neighborhood Hits	480	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

RFFL_HUMAN
NC score	0.072833 (rank : 466)	θ value	4.03905 (rank : 449)
Query Neighborhood Hits	480	Target Neighborhood Hits	175	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RNF34_HUMAN
NC score	0.072158 (rank : 467)	θ value	6.88961 (rank : 468)
Query Neighborhood Hits	480	Target Neighborhood Hits	153	Shared Neighborhood Hits	37
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RUFY3_HUMAN
NC score	0.070039 (rank : 468)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	480	Target Neighborhood Hits	594	Shared Neighborhood Hits	34
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

LRRK1_MOUSE
NC score	0.069773 (rank : 469)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	480	Target Neighborhood Hits	1267	Shared Neighborhood Hits	121
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

RHBT1_HUMAN
NC score	0.068399 (rank : 470)	θ value	0.0330416 (rank : 374)
Query Neighborhood Hits	480	Target Neighborhood Hits	262	Shared Neighborhood Hits	79
SwissProt Accessions	O94844	Gene names	RHOBTB1, KIAA0740
Domain Architecture
Description	Rho-related BTB domain-containing protein 1.

RHBT1_MOUSE
NC score	0.067970 (rank : 471)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	480	Target Neighborhood Hits	271	Shared Neighborhood Hits	81
SwissProt Accessions	Q9DAK3	Gene names	Rhobtb1
Domain Architecture
Description	Rho-related BTB domain-containing protein 1.

ZBTB5_MOUSE
NC score	0.065300 (rank : 472)	θ value	1.06291 (rank : 419)
Query Neighborhood Hits	480	Target Neighborhood Hits	801	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).

RUFY3_MOUSE
NC score	0.065215 (rank : 473)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	480	Target Neighborhood Hits	579	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

ZBTB5_HUMAN
NC score	0.065172 (rank : 474)	θ value	1.06291 (rank : 418)
Query Neighborhood Hits	480	Target Neighborhood Hits	811	Shared Neighborhood Hits	100
SwissProt Accessions	O15062	Gene names	ZBTB5, KIAA0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5.

MMRN1_HUMAN
NC score	0.064601 (rank : 475)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	480	Target Neighborhood Hits	636	Shared Neighborhood Hits	41
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

FADD_MOUSE
NC score	0.063773 (rank : 476)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	480	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

ZBTB9_HUMAN
NC score	0.060774 (rank : 477)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	480	Target Neighborhood Hits	764	Shared Neighborhood Hits	94
SwissProt Accessions	Q96C00	Gene names	ZBTB9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

ZBTB9_MOUSE
NC score	0.059175 (rank : 478)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	480	Target Neighborhood Hits	780	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

MIPO1_MOUSE
NC score	0.058934 (rank : 479)	θ value	0.21417 (rank : 394)
Query Neighborhood Hits	480	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D9F8	Gene names	Mipol1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein homolog.

FADD_HUMAN
NC score	0.057441 (rank : 480)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	480	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

ZBTB8_MOUSE
NC score	0.056300 (rank : 481)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	480	Target Neighborhood Hits	791	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CII0	Gene names	Zbtb8
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 8.

ZBTB3_HUMAN
NC score	0.055923 (rank : 482)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	480	Target Neighborhood Hits	910	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

REL_MOUSE
NC score	0.055669 (rank : 483)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	480	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

ZBT10_HUMAN
NC score	0.055332 (rank : 484)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	480	Target Neighborhood Hits	831	Shared Neighborhood Hits	101
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

REL_HUMAN
NC score	0.055311 (rank : 485)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	480	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

LCE1B_HUMAN
NC score	0.055003 (rank : 486)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	480	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

ZBTB8_HUMAN
NC score	0.054853 (rank : 487)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	480	Target Neighborhood Hits	786	Shared Neighborhood Hits	95
SwissProt Accessions	Q8NAP8, Q5VXR5	Gene names	ZBTB8
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 8.

ZBTB3_MOUSE
NC score	0.054736 (rank : 488)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	480	Target Neighborhood Hits	792	Shared Neighborhood Hits	89
SwissProt Accessions	Q91X45, Q8BIJ4	Gene names	Zbtb3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

RELB_MOUSE
NC score	0.054312 (rank : 489)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	480	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

RELB_HUMAN
NC score	0.054263 (rank : 490)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	480	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

KMHN1_MOUSE
NC score	0.054096 (rank : 491)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	480	Target Neighborhood Hits	949	Shared Neighborhood Hits	44
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

GOGA4_HUMAN
NC score	0.054033 (rank : 492)	θ value	0.0148317 (rank : 366)
Query Neighborhood Hits	480	Target Neighborhood Hits	2034	Shared Neighborhood Hits	66
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

TF65_MOUSE
NC score	0.053838 (rank : 493)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	480	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

PIBF1_HUMAN
NC score	0.053681 (rank : 494)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	480	Target Neighborhood Hits	1041	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

ATRN_HUMAN
NC score	0.053549 (rank : 495)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	480	Target Neighborhood Hits	525	Shared Neighborhood Hits	53
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

KMHN1_HUMAN
NC score	0.053532 (rank : 496)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	480	Target Neighborhood Hits	950	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

ZN295_HUMAN
NC score	0.053422 (rank : 497)	θ value	4.03905 (rank : 452)
Query Neighborhood Hits	480	Target Neighborhood Hits	847	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

TRDN_HUMAN
NC score	0.053414 (rank : 498)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	480	Target Neighborhood Hits	542	Shared Neighborhood Hits	26
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TF65_HUMAN
NC score	0.052950 (rank : 499)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	480	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

JAG2_MOUSE
NC score	0.052802 (rank : 500)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	480	Target Neighborhood Hits	504	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LCE1D_HUMAN
NC score	0.052276 (rank : 501)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	480	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

TRPC1_HUMAN
NC score	0.052156 (rank : 502)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	480	Target Neighborhood Hits	91	Shared Neighborhood Hits	58
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

JAG2_HUMAN
NC score	0.051663 (rank : 503)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	480	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LCE1C_HUMAN
NC score	0.051643 (rank : 504)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	480	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

JAG1_HUMAN
NC score	0.051618 (rank : 505)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	480	Target Neighborhood Hits	514	Shared Neighborhood Hits	9
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DNER_MOUSE
NC score	0.051510 (rank : 506)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	480	Target Neighborhood Hits	413	Shared Neighborhood Hits	9
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

JAG1_MOUSE
NC score	0.051260 (rank : 507)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	480	Target Neighborhood Hits	518	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DNER_HUMAN
NC score	0.050583 (rank : 508)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	480	Target Neighborhood Hits	460	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CP135_HUMAN
NC score	0.050326 (rank : 509)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	480	Target Neighborhood Hits	1290	Shared Neighborhood Hits	50
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CCD41_HUMAN
NC score	0.050287 (rank : 510)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	480	Target Neighborhood Hits	1139	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

TRIPB_HUMAN
NC score	0.050284 (rank : 511)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	480	Target Neighborhood Hits	1587	Shared Neighborhood Hits	59
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CRUM2_HUMAN
NC score	0.050173 (rank : 512)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	480	Target Neighborhood Hits	453	Shared Neighborhood Hits	9
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CI039_HUMAN
NC score	0.050092 (rank : 513)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	480	Target Neighborhood Hits	1171	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

GOGA4_MOUSE
NC score	0.047967 (rank : 514)	θ value	8.99809 (rank : 471)
Query Neighborhood Hits	480	Target Neighborhood Hits	1939	Shared Neighborhood Hits	64
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SMC4_HUMAN
NC score	0.047807 (rank : 515)	θ value	0.21417 (rank : 395)
Query Neighborhood Hits	480	Target Neighborhood Hits	937	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

ZBT37_HUMAN
NC score	0.045147 (rank : 516)	θ value	1.81305 (rank : 436)
Query Neighborhood Hits	480	Target Neighborhood Hits	815	Shared Neighborhood Hits	93
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

ZBT34_HUMAN
NC score	0.043201 (rank : 517)	θ value	2.36792 (rank : 439)
Query Neighborhood Hits	480	Target Neighborhood Hits	799	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NCN2	Gene names	ZBTB34, KIAA1993
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 34.

GCC1_HUMAN
NC score	0.042312 (rank : 518)	θ value	1.81305 (rank : 428)
Query Neighborhood Hits	480	Target Neighborhood Hits	887	Shared Neighborhood Hits	40
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

MIPO1_HUMAN
NC score	0.039631 (rank : 519)	θ value	8.99809 (rank : 474)
Query Neighborhood Hits	480	Target Neighborhood Hits	486	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

Z297B_MOUSE
NC score	0.036326 (rank : 520)	θ value	6.88961 (rank : 470)
Query Neighborhood Hits	480	Target Neighborhood Hits	806	Shared Neighborhood Hits	93
SwissProt Accessions	Q9DAI4	Gene names	Znf297b, Kiaa0414, Zfp297b
Domain Architecture
Description	Zinc finger protein 297B.

NELL1_HUMAN
NC score	0.035107 (rank : 521)	θ value	6.88961 (rank : 463)
Query Neighborhood Hits	480	Target Neighborhood Hits	451	Shared Neighborhood Hits	10
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

ZN238_MOUSE
NC score	0.033253 (rank : 522)	θ value	8.99809 (rank : 480)
Query Neighborhood Hits	480	Target Neighborhood Hits	837	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WUK6	Gene names	Znf238, Rp58, Zfp238
Domain Architecture
Description	Zinc finger protein 238 (Zfp-238) (Transcriptional repressor RP58) (58 kDa repressor protein).

ZN238_HUMAN
NC score	0.032889 (rank : 523)	θ value	8.99809 (rank : 479)
Query Neighborhood Hits	480	Target Neighborhood Hits	836	Shared Neighborhood Hits	98
SwissProt Accessions	Q99592, Q13397, Q5VU40, Q8N463	Gene names	ZNF238, RP58, TAZ1, ZBTB18
Domain Architecture
Description	Zinc finger protein 238 (Transcriptional repressor RP58) (58 kDa repressor protein) (Zinc finger protein C2H2-171) (Translin-associated zinc finger protein 1) (TAZ-1) (Zinc finger and BTB domain-containing protein 18).

ZN131_MOUSE
NC score	0.032768 (rank : 524)	θ value	3.0926 (rank : 446)
Query Neighborhood Hits	480	Target Neighborhood Hits	833	Shared Neighborhood Hits	99
SwissProt Accessions	Q8K3J5, Q3UYZ4, Q80UU7, Q8C8D0, Q9D042	Gene names	Znf131, Zfp131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

ZN131_HUMAN
NC score	0.032550 (rank : 525)	θ value	3.0926 (rank : 445)
Query Neighborhood Hits	480	Target Neighborhood Hits	833	Shared Neighborhood Hits	97
SwissProt Accessions	P52739, Q6PIF0	Gene names	ZNF131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

CN037_MOUSE
NC score	0.032453 (rank : 526)	θ value	0.21417 (rank : 393)
Query Neighborhood Hits	480	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

ZBTB2_HUMAN
NC score	0.027697 (rank : 527)	θ value	2.36792 (rank : 440)
Query Neighborhood Hits	480	Target Neighborhood Hits	752	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N680, Q5SZ81, Q9P245	Gene names	ZBTB2, KIAA1483, ZNF437
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 2.

ZBT12_HUMAN
NC score	0.027309 (rank : 528)	θ value	5.27518 (rank : 457)
Query Neighborhood Hits	480	Target Neighborhood Hits	784	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y330, Q5JQ98	Gene names	ZBTB12, C6orf46, G10, NG35
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 12 (Protein G10).

ZF161_HUMAN
NC score	0.027095 (rank : 529)	θ value	1.06291 (rank : 420)
Query Neighborhood Hits	480	Target Neighborhood Hits	822	Shared Neighborhood Hits	97
SwissProt Accessions	O43829, O00403	Gene names	ZFP161, ZBTB14
Domain Architecture
Description	Zinc finger protein 161 homolog (Zfp-161) (Zinc finger protein 5) (hZF5) (Zinc finger and BTB domain-containing protein 14).

ZF161_MOUSE
NC score	0.026961 (rank : 530)	θ value	1.38821 (rank : 425)
Query Neighborhood Hits	480	Target Neighborhood Hits	821	Shared Neighborhood Hits	97
SwissProt Accessions	Q08376	Gene names	Zfp161, Zfp-5, Zfp5
Domain Architecture
Description	Zinc finger protein 161 (Zfp-161) (Zinc finger protein 5) (ZF5).

ZBTB6_HUMAN
NC score	0.026676 (rank : 531)	θ value	3.0926 (rank : 443)
Query Neighborhood Hits	480	Target Neighborhood Hits	805	Shared Neighborhood Hits	84
SwissProt Accessions	Q15916	Gene names	ZBTB6, ZID, ZNF482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain).

ZBTB6_MOUSE
NC score	0.026320 (rank : 532)	θ value	3.0926 (rank : 444)
Query Neighborhood Hits	480	Target Neighborhood Hits	793	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K088, Q8BLM4	Gene names	Zbtb6, Zfp482, Znf482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482).

NOL1_HUMAN
NC score	0.026145 (rank : 533)	θ value	1.81305 (rank : 429)
Query Neighborhood Hits	480	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	P46087	Gene names	NOL1
Domain Architecture
Description	Proliferating-cell nucleolar antigen p120 (Proliferation-associated nucleolar protein p120).

ZN318_HUMAN
NC score	0.023613 (rank : 534)	θ value	1.38821 (rank : 426)
Query Neighborhood Hits	480	Target Neighborhood Hits	497	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

MRCKB_MOUSE
NC score	0.023465 (rank : 535)	θ value	8.99809 (rank : 475)
Query Neighborhood Hits	480	Target Neighborhood Hits	2180	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

KI21A_HUMAN
NC score	0.023166 (rank : 536)	θ value	8.99809 (rank : 472)
Query Neighborhood Hits	480	Target Neighborhood Hits	1543	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

ZBT45_HUMAN
NC score	0.021142 (rank : 537)	θ value	1.81305 (rank : 437)
Query Neighborhood Hits	480	Target Neighborhood Hits	901	Shared Neighborhood Hits	85
SwissProt Accessions	Q96K62	Gene names	ZBTB45, ZNF499
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499).

ZBT38_HUMAN
NC score	0.020686 (rank : 538)	θ value	1.38821 (rank : 424)
Query Neighborhood Hits	480	Target Neighborhood Hits	885	Shared Neighborhood Hits	101
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

ZBT40_HUMAN
NC score	0.020269 (rank : 539)	θ value	7.1131e-05 (rank : 288)
Query Neighborhood Hits	480	Target Neighborhood Hits	949	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ZBT16_HUMAN
NC score	0.020041 (rank : 540)	θ value	0.0148317 (rank : 367)
Query Neighborhood Hits	480	Target Neighborhood Hits	1010	Shared Neighborhood Hits	99
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

KI21A_MOUSE
NC score	0.019357 (rank : 541)	θ value	8.99809 (rank : 473)
Query Neighborhood Hits	480	Target Neighborhood Hits	1317	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

RC3H1_MOUSE
NC score	0.019013 (rank : 542)	θ value	0.813845 (rank : 412)
Query Neighborhood Hits	480	Target Neighborhood Hits	244	Shared Neighborhood Hits	13
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

ZBT17_HUMAN
NC score	0.018327 (rank : 543)	θ value	1.38821 (rank : 423)
Query Neighborhood Hits	480	Target Neighborhood Hits	925	Shared Neighborhood Hits	106
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

RC3H1_HUMAN
NC score	0.018178 (rank : 544)	θ value	0.813845 (rank : 411)
Query Neighborhood Hits	480	Target Neighborhood Hits	433	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TDRKH_HUMAN
NC score	0.010918 (rank : 545)	θ value	0.62314 (rank : 406)
Query Neighborhood Hits	480	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TRRAP_MOUSE
NC score	0.009148 (rank : 546)	θ value	5.27518 (rank : 456)
Query Neighborhood Hits	480	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

TRRAP_HUMAN
NC score	0.008797 (rank : 547)	θ value	5.27518 (rank : 455)
Query Neighborhood Hits	480	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

COE3_MOUSE
NC score	0.006871 (rank : 548)	θ value	6.88961 (rank : 460)
Query Neighborhood Hits	480	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

PDZD6_HUMAN
NC score	0.005893 (rank : 549)	θ value	6.88961 (rank : 464)
Query Neighborhood Hits	480	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PK3CG_HUMAN
NC score	0.002962 (rank : 550)	θ value	6.88961 (rank : 466)
Query Neighborhood Hits	480	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.002953 (rank : 551)	θ value	6.88961 (rank : 467)
Query Neighborhood Hits	480	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PGFRA_HUMAN
NC score	0.002795 (rank : 552)	θ value	6.88961 (rank : 465)
Query Neighborhood Hits	480	Target Neighborhood Hits	980	Shared Neighborhood Hits	17
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
NC score	0.002599 (rank : 553)	θ value	8.99809 (rank : 476)
Query Neighborhood Hits	480	Target Neighborhood Hits	975	Shared Neighborhood Hits	17
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

TRI56_HUMAN
NC score	-0.001364 (rank : 554)	θ value	6.88961 (rank : 469)
Query Neighborhood Hits	480	Target Neighborhood Hits	339	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI41_HUMAN
NC score	-0.001652 (rank : 555)	θ value	8.99809 (rank : 478)
Query Neighborhood Hits	480	Target Neighborhood Hits	349	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.