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Network neighborhood for query Sequence : FADD_MOUSE

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FADD_MOUSE
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FADD_MOUSE
θ value	1.40038e-85 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

FADD_HUMAN
θ value	3.0428e-56 (rank : 2)	NC score	0.961678 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

RIPK1_MOUSE
θ value	2.21117e-06 (rank : 3)	NC score	0.076069 (rank : 28)
Query Neighborhood Hits	23	Target Neighborhood Hits	874	Shared Neighborhood Hits	11
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

CASP8_MOUSE
θ value	4.92598e-06 (rank : 4)	NC score	0.277227 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	O89110, O35669	Gene names	Casp8
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

RIPK1_HUMAN
θ value	8.40245e-06 (rank : 5)	NC score	0.073341 (rank : 29)
Query Neighborhood Hits	23	Target Neighborhood Hits	891	Shared Neighborhood Hits	12
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ANK2_HUMAN
θ value	1.43324e-05 (rank : 6)	NC score	0.138259 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	1615	Shared Neighborhood Hits	10
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CASP8_HUMAN
θ value	3.19293e-05 (rank : 7)	NC score	0.273121 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q14790, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81	Gene names	CASP8, MCH5
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) (ICE-like apoptotic protease 5) (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous ICE/CED-3-like protease) (FADD-like ICE) (FLICE) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

ANK1_MOUSE
θ value	7.1131e-05 (rank : 8)	NC score	0.148686 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	430	Shared Neighborhood Hits	9
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK1_HUMAN
θ value	9.29e-05 (rank : 9)	NC score	0.146586 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	416	Shared Neighborhood Hits	8
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

PEA15_HUMAN
θ value	0.00020696 (rank : 10)	NC score	0.319637 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q15121, O00511	Gene names	PEA15
Domain Architecture
Description	Astrocytic phosphoprotein PEA-15 (Phosphoprotein enriched in diabetes) (PED).

PEA15_MOUSE
θ value	0.000270298 (rank : 11)	NC score	0.318430 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q62048, Q3U5N7	Gene names	Pea15
Domain Architecture
Description	Astrocytic phosphoprotein PEA-15.

ANK3_HUMAN
θ value	0.000461057 (rank : 12)	NC score	0.140868 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	853	Shared Neighborhood Hits	11
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CASPA_HUMAN
θ value	0.00102713 (rank : 13)	NC score	0.246117 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q92851, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7	Gene names	CASP10, MCH4
Domain Architecture
Description	Caspase-10 precursor (EC 3.4.22.-) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12].

TNR1A_MOUSE
θ value	0.0252991 (rank : 14)	NC score	0.110716 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

CJ092_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.120157 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYW2, Q5JSF7, Q9NTQ5	Gene names	C10orf92
Domain Architecture	No domain graphic available
Description	Protein C10orf92.

CFLAR_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.187579 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	O35732, O35707, O35733	Gene names	Cflar, Cash
Domain Architecture
Description	CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin) [Contains: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12].

CFLAR_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.196922 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	O15519, O14673, O14674, O14675, O15137, O15138, O15356, O15510, O43618, O43619, O43620, O60458, O60459, Q96TE4, Q9UEW1	Gene names	CFLAR, CASH, CLARP, MRIT
Domain Architecture
Description	CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin) [Contains: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12].

TNR6_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.061434 (rank : 42)
Query Neighborhood Hits	23	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.060371 (rank : 48)
Query Neighborhood Hits	23	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

CJ120_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.044955 (rank : 109)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SQS8	Gene names	C10orf120
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf120.

TNR1A_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.101045 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	121	Shared Neighborhood Hits	11
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

CD2L7_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.011546 (rank : 111)
Query Neighborhood Hits	23	Target Neighborhood Hits	1275	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

SNX24_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.021606 (rank : 110)
Query Neighborhood Hits	23	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y343, Q6UY33	Gene names	SNX24
Domain Architecture
Description	Sorting nexin-24.

ANFY1_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.063857 (rank : 35)
Query Neighborhood Hits	23	Target Neighborhood Hits	480	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
θ value	θ > 10 (rank : 25)	NC score	0.063773 (rank : 38)
Query Neighborhood Hits	23	Target Neighborhood Hits	480	Shared Neighborhood Hits	4
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKK1_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.054660 (rank : 67)
Query Neighborhood Hits	23	Target Neighborhood Hits	1075	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANKK1_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.055307 (rank : 63)
Query Neighborhood Hits	23	Target Neighborhood Hits	1072	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANKR5_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.053689 (rank : 72)
Query Neighborhood Hits	23	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR6_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.052027 (rank : 87)
Query Neighborhood Hits	23	Target Neighborhood Hits	439	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANKS1_MOUSE
θ value	θ > 10 (rank : 30)	NC score	0.051519 (rank : 93)
Query Neighborhood Hits	23	Target Neighborhood Hits	453	Shared Neighborhood Hits	4
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKS6_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.057504 (rank : 54)
Query Neighborhood Hits	23	Target Neighborhood Hits	411	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKS6_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.058662 (rank : 51)
Query Neighborhood Hits	23	Target Neighborhood Hits	435	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKY1_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.060495 (rank : 47)
Query Neighborhood Hits	23	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANR16_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.061208 (rank : 44)
Query Neighborhood Hits	23	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR22_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.059383 (rank : 49)
Query Neighborhood Hits	23	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR28_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.063836 (rank : 36)
Query Neighborhood Hits	23	Target Neighborhood Hits	314	Shared Neighborhood Hits	4
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.063231 (rank : 41)
Query Neighborhood Hits	23	Target Neighborhood Hits	314	Shared Neighborhood Hits	4
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR29_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.055799 (rank : 58)
Query Neighborhood Hits	23	Target Neighborhood Hits	294	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR40_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.050417 (rank : 104)
Query Neighborhood Hits	23	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR41_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.053592 (rank : 74)
Query Neighborhood Hits	23	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR42_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.055354 (rank : 62)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR42_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.058407 (rank : 53)
Query Neighborhood Hits	23	Target Neighborhood Hits	334	Shared Neighborhood Hits	4
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR44_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.063476 (rank : 40)
Query Neighborhood Hits	23	Target Neighborhood Hits	318	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR45_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.052103 (rank : 86)
Query Neighborhood Hits	23	Target Neighborhood Hits	204	Shared Neighborhood Hits	4
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR49_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.052479 (rank : 83)
Query Neighborhood Hits	23	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANR49_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.053206 (rank : 78)
Query Neighborhood Hits	23	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR50_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.066608 (rank : 32)
Query Neighborhood Hits	23	Target Neighborhood Hits	361	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR52_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.064050 (rank : 34)
Query Neighborhood Hits	23	Target Neighborhood Hits	322	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.063792 (rank : 37)
Query Neighborhood Hits	23	Target Neighborhood Hits	318	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ASB10_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.052937 (rank : 81)
Query Neighborhood Hits	23	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.051781 (rank : 90)
Query Neighborhood Hits	23	Target Neighborhood Hits	301	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB11_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.050864 (rank : 99)
Query Neighborhood Hits	23	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB12_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.050993 (rank : 98)
Query Neighborhood Hits	23	Target Neighborhood Hits	263	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB12_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.050480 (rank : 101)
Query Neighborhood Hits	23	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB13_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.050456 (rank : 102)
Query Neighborhood Hits	23	Target Neighborhood Hits	293	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.050327 (rank : 106)
Query Neighborhood Hits	23	Target Neighborhood Hits	293	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB14_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.055553 (rank : 59)
Query Neighborhood Hits	23	Target Neighborhood Hits	293	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB15_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.058549 (rank : 52)
Query Neighborhood Hits	23	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB15_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.059003 (rank : 50)
Query Neighborhood Hits	23	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB16_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.050452 (rank : 103)
Query Neighborhood Hits	23	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB16_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.051066 (rank : 97)
Query Neighborhood Hits	23	Target Neighborhood Hits	306	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.054925 (rank : 65)
Query Neighborhood Hits	23	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB2_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.054533 (rank : 68)
Query Neighborhood Hits	23	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.055390 (rank : 60)
Query Neighborhood Hits	23	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.056820 (rank : 57)
Query Neighborhood Hits	23	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB4_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.054330 (rank : 70)
Query Neighborhood Hits	23	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.053666 (rank : 73)
Query Neighborhood Hits	23	Target Neighborhood Hits	265	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB5_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.051562 (rank : 92)
Query Neighborhood Hits	23	Target Neighborhood Hits	283	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB5_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.051931 (rank : 88)
Query Neighborhood Hits	23	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB7_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.053286 (rank : 77)
Query Neighborhood Hits	23	Target Neighborhood Hits	296	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.053188 (rank : 79)
Query Neighborhood Hits	23	Target Neighborhood Hits	296	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB9_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.050284 (rank : 108)
Query Neighborhood Hits	23	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB9_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.053481 (rank : 75)
Query Neighborhood Hits	23	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASZ1_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.050287 (rank : 107)
Query Neighborhood Hits	23	Target Neighborhood Hits	341	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASZ1_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.051296 (rank : 95)
Query Neighborhood Hits	23	Target Neighborhood Hits	319	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CASP1_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.052786 (rank : 82)
Query Neighborhood Hits	23	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P29466, Q9UCN3	Gene names	CASP1, IL1BC, IL1BCE
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

CASP1_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.057001 (rank : 56)
Query Neighborhood Hits	23	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	P29452	Gene names	Casp1, Il1bc
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

CASP2_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.087962 (rank : 24)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	P42575, P42576, Q59F21, Q7KZL6, Q86UJ3, Q9BUP7, Q9BZK9	Gene names	CASP2, ICH1
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (ICH- 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

CASP2_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.086678 (rank : 25)
Query Neighborhood Hits	23	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	P29594, O08737, Q3TCM0, Q8C9H7, Q8K241	Gene names	Casp2, Ich1, Nedd-2, Nedd2
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural precursor cell expressed developmentally down- regulated protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

CASP3_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.097271 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	P42574, Q96AN1, Q96KP2	Gene names	CASP3, CPP32
Domain Architecture
Description	Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit].

CASP3_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.097938 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P70677, O08668, Q8CHV5, Q9QWI4	Gene names	Casp3, Cpp32
Domain Architecture
Description	Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) (LICE) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit].

CASP4_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.051654 (rank : 91)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P70343, O08735	Gene names	Casp4, Casp11, Caspl, Ich3
Domain Architecture
Description	Caspase-4 precursor (EC 3.4.22.-) (CASP-4) (Caspase-11) (ICH-3 protease) [Contains: Caspase-4 subunit p10; Caspase-4 subunit p20].

CASP5_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.050537 (rank : 100)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P51878	Gene names	CASP5, ICH3
Domain Architecture
Description	Caspase-5 precursor (EC 3.4.22.-) (CASP-5) (ICH-3 protease) (TY protease) (ICE(rel)-III) [Contains: Caspase-5 subunit p20; Caspase-5 subunit p10].

CASP6_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.096464 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P55212, Q9BQE7	Gene names	CASP6, MCH2
Domain Architecture
Description	Caspase-6 precursor (EC 3.4.22.-) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11].

CASP6_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.096603 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	O08738	Gene names	Casp6
Domain Architecture
Description	Caspase-6 precursor (EC 3.4.22.-) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11].

CASP7_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.103176 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P55210, Q13364, Q96BA0	Gene names	CASP7, MCH3
Domain Architecture
Description	Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3) (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11].

CASP7_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.105059 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P97864, O08669	Gene names	Casp7, Lice2, Mch3
Domain Architecture
Description	Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (LICE2 cysteine protease) (Apoptotic protease Mch-3) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11].

CASP9_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.099931 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P55211, O95348, Q92852, Q9BQ62, Q9UEQ3, Q9UIJ8	Gene names	CASP9, MCH6
Domain Architecture
Description	Caspase-9 precursor (EC 3.4.22.-) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease- activating factor 3) (APAF-3) [Contains: Caspase-9 subunit p35; Caspase-9 subunit p10].

CASPE_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.079707 (rank : 26)
Query Neighborhood Hits	23	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	P31944, O95823, Q3SYC9	Gene names	CASP14
Domain Architecture
Description	Caspase-14 precursor (EC 3.4.22.-) (CASP-14) [Contains: Caspase-14 subunit 1; Caspase-14 subunit 2].

CASPE_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.078441 (rank : 27)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	O89094	Gene names	Casp14
Domain Architecture
Description	Caspase-14 precursor (EC 3.4.22.-) (CASP-14) (Mini-ICE) (MICE) [Contains: Caspase-14 subunit 1; Caspase-14 subunit 2].

CD2A1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.054841 (rank : 66)
Query Neighborhood Hits	23	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CDN2B_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.052110 (rank : 85)
Query Neighborhood Hits	23	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CDN2D_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.053385 (rank : 76)
Query Neighborhood Hits	23	Target Neighborhood Hits	268	Shared Neighborhood Hits	4
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CDN2D_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.053809 (rank : 71)
Query Neighborhood Hits	23	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CT086_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.057102 (rank : 55)
Query Neighborhood Hits	23	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

IKBB_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.054423 (rank : 69)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBB_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.052113 (rank : 84)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

INVS_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.060654 (rank : 46)
Query Neighborhood Hits	23	Target Neighborhood Hits	455	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.061332 (rank : 43)
Query Neighborhood Hits	23	Target Neighborhood Hits	609	Shared Neighborhood Hits	4
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

PA2G6_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.055221 (rank : 64)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PA2G6_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.055375 (rank : 61)
Query Neighborhood Hits	23	Target Neighborhood Hits	293	Shared Neighborhood Hits	4
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PIDD_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.051818 (rank : 89)
Query Neighborhood Hits	23	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

PP16B_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.050371 (rank : 105)
Query Neighborhood Hits	23	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

RIPK4_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.053186 (rank : 80)
Query Neighborhood Hits	23	Target Neighborhood Hits	1094	Shared Neighborhood Hits	7
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

RN5A_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.051514 (rank : 94)
Query Neighborhood Hits	23	Target Neighborhood Hits	899	Shared Neighborhood Hits	7
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

TNKS1_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.068238 (rank : 31)
Query Neighborhood Hits	23	Target Neighborhood Hits	477	Shared Neighborhood Hits	4
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.068395 (rank : 30)
Query Neighborhood Hits	23	Target Neighborhood Hits	361	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TR10B_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.061164 (rank : 45)
Query Neighborhood Hits	23	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TRADD_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.051117 (rank : 96)
Query Neighborhood Hits	23	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q15628	Gene names	TRADD
Domain Architecture
Description	Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain).

TRPA1_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.064346 (rank : 33)
Query Neighborhood Hits	23	Target Neighborhood Hits	339	Shared Neighborhood Hits	4
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

TRPA1_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.063611 (rank : 39)
Query Neighborhood Hits	23	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

Hits sorted by NC score

FADD_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.40038e-85 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

FADD_HUMAN
NC score	0.961678 (rank : 2)	θ value	3.0428e-56 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

PEA15_HUMAN
NC score	0.319637 (rank : 3)	θ value	0.00020696 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q15121, O00511	Gene names	PEA15
Domain Architecture
Description	Astrocytic phosphoprotein PEA-15 (Phosphoprotein enriched in diabetes) (PED).

PEA15_MOUSE
NC score	0.318430 (rank : 4)	θ value	0.000270298 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	Q62048, Q3U5N7	Gene names	Pea15
Domain Architecture
Description	Astrocytic phosphoprotein PEA-15.

CASP8_MOUSE
NC score	0.277227 (rank : 5)	θ value	4.92598e-06 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	O89110, O35669	Gene names	Casp8
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

CASP8_HUMAN
NC score	0.273121 (rank : 6)	θ value	3.19293e-05 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q14790, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81	Gene names	CASP8, MCH5
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) (ICE-like apoptotic protease 5) (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous ICE/CED-3-like protease) (FADD-like ICE) (FLICE) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

CASPA_HUMAN
NC score	0.246117 (rank : 7)	θ value	0.00102713 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q92851, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7	Gene names	CASP10, MCH4
Domain Architecture
Description	Caspase-10 precursor (EC 3.4.22.-) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12].

CFLAR_HUMAN
NC score	0.196922 (rank : 8)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	O15519, O14673, O14674, O14675, O15137, O15138, O15356, O15510, O43618, O43619, O43620, O60458, O60459, Q96TE4, Q9UEW1	Gene names	CFLAR, CASH, CLARP, MRIT
Domain Architecture
Description	CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin) [Contains: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12].

CFLAR_MOUSE
NC score	0.187579 (rank : 9)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	O35732, O35707, O35733	Gene names	Cflar, Cash
Domain Architecture
Description	CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin) [Contains: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12].

ANK1_MOUSE
NC score	0.148686 (rank : 10)	θ value	7.1131e-05 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	430	Shared Neighborhood Hits	9
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK1_HUMAN
NC score	0.146586 (rank : 11)	θ value	9.29e-05 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	416	Shared Neighborhood Hits	8
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK3_HUMAN
NC score	0.140868 (rank : 12)	θ value	0.000461057 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	853	Shared Neighborhood Hits	11
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANK2_HUMAN
NC score	0.138259 (rank : 13)	θ value	1.43324e-05 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	1615	Shared Neighborhood Hits	10
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CJ092_HUMAN
NC score	0.120157 (rank : 14)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYW2, Q5JSF7, Q9NTQ5	Gene names	C10orf92
Domain Architecture	No domain graphic available
Description	Protein C10orf92.

TNR1A_MOUSE
NC score	0.110716 (rank : 15)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

CASP7_MOUSE
NC score	0.105059 (rank : 16)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P97864, O08669	Gene names	Casp7, Lice2, Mch3
Domain Architecture
Description	Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (LICE2 cysteine protease) (Apoptotic protease Mch-3) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11].

CASP7_HUMAN
NC score	0.103176 (rank : 17)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	23	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	P55210, Q13364, Q96BA0	Gene names	CASP7, MCH3
Domain Architecture
Description	Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3) (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11].

TNR1A_HUMAN
NC score	0.101045 (rank : 18)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	121	Shared Neighborhood Hits	11
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

CASP9_HUMAN
NC score	0.099931 (rank : 19)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	23	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P55211, O95348, Q92852, Q9BQ62, Q9UEQ3, Q9UIJ8	Gene names	CASP9, MCH6
Domain Architecture
Description	Caspase-9 precursor (EC 3.4.22.-) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease- activating factor 3) (APAF-3) [Contains: Caspase-9 subunit p35; Caspase-9 subunit p10].

CASP3_MOUSE
NC score	0.097938 (rank : 20)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P70677, O08668, Q8CHV5, Q9QWI4	Gene names	Casp3, Cpp32
Domain Architecture
Description	Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) (LICE) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit].

CASP3_HUMAN
NC score	0.097271 (rank : 21)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	P42574, Q96AN1, Q96KP2	Gene names	CASP3, CPP32
Domain Architecture
Description	Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit].

CASP6_MOUSE
NC score	0.096603 (rank : 22)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	O08738	Gene names	Casp6
Domain Architecture
Description	Caspase-6 precursor (EC 3.4.22.-) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11].

CASP6_HUMAN
NC score	0.096464 (rank : 23)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	23	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P55212, Q9BQE7	Gene names	CASP6, MCH2
Domain Architecture
Description	Caspase-6 precursor (EC 3.4.22.-) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11].

CASP2_HUMAN
NC score	0.087962 (rank : 24)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	P42575, P42576, Q59F21, Q7KZL6, Q86UJ3, Q9BUP7, Q9BZK9	Gene names	CASP2, ICH1
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (ICH- 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

CASP2_MOUSE
NC score	0.086678 (rank : 25)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	23	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	P29594, O08737, Q3TCM0, Q8C9H7, Q8K241	Gene names	Casp2, Ich1, Nedd-2, Nedd2
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural precursor cell expressed developmentally down- regulated protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

CASPE_HUMAN
NC score	0.079707 (rank : 26)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	23	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	P31944, O95823, Q3SYC9	Gene names	CASP14
Domain Architecture
Description	Caspase-14 precursor (EC 3.4.22.-) (CASP-14) [Contains: Caspase-14 subunit 1; Caspase-14 subunit 2].

CASPE_MOUSE
NC score	0.078441 (rank : 27)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	O89094	Gene names	Casp14
Domain Architecture
Description	Caspase-14 precursor (EC 3.4.22.-) (CASP-14) (Mini-ICE) (MICE) [Contains: Caspase-14 subunit 1; Caspase-14 subunit 2].

RIPK1_MOUSE
NC score	0.076069 (rank : 28)	θ value	2.21117e-06 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	874	Shared Neighborhood Hits	11
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_HUMAN
NC score	0.073341 (rank : 29)	θ value	8.40245e-06 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	891	Shared Neighborhood Hits	12
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

TNKS2_HUMAN
NC score	0.068395 (rank : 30)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	23	Target Neighborhood Hits	361	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
NC score	0.068238 (rank : 31)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	23	Target Neighborhood Hits	477	Shared Neighborhood Hits	4
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR50_HUMAN
NC score	0.066608 (rank : 32)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	23	Target Neighborhood Hits	361	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

TRPA1_HUMAN
NC score	0.064346 (rank : 33)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	23	Target Neighborhood Hits	339	Shared Neighborhood Hits	4
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANR52_HUMAN
NC score	0.064050 (rank : 34)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	23	Target Neighborhood Hits	322	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANFY1_HUMAN
NC score	0.063857 (rank : 35)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	23	Target Neighborhood Hits	480	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR28_HUMAN
NC score	0.063836 (rank : 36)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	23	Target Neighborhood Hits	314	Shared Neighborhood Hits	4
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_MOUSE
NC score	0.063792 (rank : 37)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	23	Target Neighborhood Hits	318	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANFY1_MOUSE
NC score	0.063773 (rank : 38)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	23	Target Neighborhood Hits	480	Shared Neighborhood Hits	4
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

TRPA1_MOUSE
NC score	0.063611 (rank : 39)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	23	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANR44_HUMAN
NC score	0.063476 (rank : 40)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	23	Target Neighborhood Hits	318	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR28_MOUSE
NC score	0.063231 (rank : 41)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	23	Target Neighborhood Hits	314	Shared Neighborhood Hits	4
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

TNR6_HUMAN
NC score	0.061434 (rank : 42)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

INVS_MOUSE
NC score	0.061332 (rank : 43)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	23	Target Neighborhood Hits	609	Shared Neighborhood Hits	4
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR16_HUMAN
NC score	0.061208 (rank : 44)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	23	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

TR10B_MOUSE
NC score	0.061164 (rank : 45)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	23	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

INVS_HUMAN
NC score	0.060654 (rank : 46)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	23	Target Neighborhood Hits	455	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANKY1_HUMAN
NC score	0.060495 (rank : 47)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	23	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

TNR6_MOUSE
NC score	0.060371 (rank : 48)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

ANR22_HUMAN
NC score	0.059383 (rank : 49)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	23	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASB15_MOUSE
NC score	0.059003 (rank : 50)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	23	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANKS6_MOUSE
NC score	0.058662 (rank : 51)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	23	Target Neighborhood Hits	435	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASB15_HUMAN
NC score	0.058549 (rank : 52)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	23	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANR42_MOUSE
NC score	0.058407 (rank : 53)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	23	Target Neighborhood Hits	334	Shared Neighborhood Hits	4
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANKS6_HUMAN
NC score	0.057504 (rank : 54)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	23	Target Neighborhood Hits	411	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CT086_HUMAN
NC score	0.057102 (rank : 55)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	23	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

CASP1_MOUSE
NC score	0.057001 (rank : 56)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	23	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	P29452	Gene names	Casp1, Il1bc
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

ASB3_MOUSE
NC score	0.056820 (rank : 57)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	23	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR29_HUMAN
NC score	0.055799 (rank : 58)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	23	Target Neighborhood Hits	294	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ASB14_MOUSE
NC score	0.055553 (rank : 59)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	23	Target Neighborhood Hits	293	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB3_HUMAN
NC score	0.055390 (rank : 60)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	23	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

PA2G6_MOUSE
NC score	0.055375 (rank : 61)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	23	Target Neighborhood Hits	293	Shared Neighborhood Hits	4
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR42_HUMAN
NC score	0.055354 (rank : 62)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANKK1_MOUSE
NC score	0.055307 (rank : 63)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	23	Target Neighborhood Hits	1072	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

PA2G6_HUMAN
NC score	0.055221 (rank : 64)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB2_HUMAN
NC score	0.054925 (rank : 65)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	23	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CD2A1_HUMAN
NC score	0.054841 (rank : 66)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	23	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANKK1_HUMAN
NC score	0.054660 (rank : 67)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	23	Target Neighborhood Hits	1075	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ASB2_MOUSE
NC score	0.054533 (rank : 68)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	23	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

IKBB_HUMAN
NC score	0.054423 (rank : 69)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ASB4_HUMAN
NC score	0.054330 (rank : 70)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	23	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CDN2D_MOUSE
NC score	0.053809 (rank : 71)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	23	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANKR5_HUMAN
NC score	0.053689 (rank : 72)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	23	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB4_MOUSE
NC score	0.053666 (rank : 73)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	23	Target Neighborhood Hits	265	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ANR41_HUMAN
NC score	0.053592 (rank : 74)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	23	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ASB9_MOUSE
NC score	0.053481 (rank : 75)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	23	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CDN2D_HUMAN
NC score	0.053385 (rank : 76)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	23	Target Neighborhood Hits	268	Shared Neighborhood Hits	4
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB7_HUMAN
NC score	0.053286 (rank : 77)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	23	Target Neighborhood Hits	296	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR49_MOUSE
NC score	0.053206 (rank : 78)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	23	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB7_MOUSE
NC score	0.053188 (rank : 79)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	23	Target Neighborhood Hits	296	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

RIPK4_HUMAN
NC score	0.053186 (rank : 80)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	23	Target Neighborhood Hits	1094	Shared Neighborhood Hits	7
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ASB10_HUMAN
NC score	0.052937 (rank : 81)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	23	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

CASP1_HUMAN
NC score	0.052786 (rank : 82)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	23	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P29466, Q9UCN3	Gene names	CASP1, IL1BC, IL1BCE
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

ANR49_HUMAN
NC score	0.052479 (rank : 83)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	23	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

IKBB_MOUSE
NC score	0.052113 (rank : 84)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

CDN2B_MOUSE
NC score	0.052110 (rank : 85)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	23	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

ANR45_MOUSE
NC score	0.052103 (rank : 86)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	23	Target Neighborhood Hits	204	Shared Neighborhood Hits	4
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANKR6_HUMAN
NC score	0.052027 (rank : 87)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	23	Target Neighborhood Hits	439	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ASB5_MOUSE
NC score	0.051931 (rank : 88)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	23	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

PIDD_HUMAN
NC score	0.051818 (rank : 89)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	23	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

ASB10_MOUSE
NC score	0.051781 (rank : 90)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	23	Target Neighborhood Hits	301	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

CASP4_MOUSE
NC score	0.051654 (rank : 91)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P70343, O08735	Gene names	Casp4, Casp11, Caspl, Ich3
Domain Architecture
Description	Caspase-4 precursor (EC 3.4.22.-) (CASP-4) (Caspase-11) (ICH-3 protease) [Contains: Caspase-4 subunit p10; Caspase-4 subunit p20].

ASB5_HUMAN
NC score	0.051562 (rank : 92)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	23	Target Neighborhood Hits	283	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANKS1_MOUSE
NC score	0.051519 (rank : 93)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	23	Target Neighborhood Hits	453	Shared Neighborhood Hits	4
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

RN5A_MOUSE
NC score	0.051514 (rank : 94)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	23	Target Neighborhood Hits	899	Shared Neighborhood Hits	7
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASZ1_MOUSE
NC score	0.051296 (rank : 95)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	23	Target Neighborhood Hits	319	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

TRADD_HUMAN
NC score	0.051117 (rank : 96)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	23	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q15628	Gene names	TRADD
Domain Architecture
Description	Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain).

ASB16_MOUSE
NC score	0.051066 (rank : 97)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	23	Target Neighborhood Hits	306	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB12_HUMAN
NC score	0.050993 (rank : 98)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	23	Target Neighborhood Hits	263	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB11_HUMAN
NC score	0.050864 (rank : 99)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	23	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

CASP5_HUMAN
NC score	0.050537 (rank : 100)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P51878	Gene names	CASP5, ICH3
Domain Architecture
Description	Caspase-5 precursor (EC 3.4.22.-) (CASP-5) (ICH-3 protease) (TY protease) (ICE(rel)-III) [Contains: Caspase-5 subunit p20; Caspase-5 subunit p10].

ASB12_MOUSE
NC score	0.050480 (rank : 101)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	23	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB13_HUMAN
NC score	0.050456 (rank : 102)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	23	Target Neighborhood Hits	293	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB16_HUMAN
NC score	0.050452 (rank : 103)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	23	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANR40_HUMAN
NC score	0.050417 (rank : 104)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	23	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

PP16B_HUMAN
NC score	0.050371 (rank : 105)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	23	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASB13_MOUSE
NC score	0.050327 (rank : 106)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	23	Target Neighborhood Hits	293	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASZ1_HUMAN
NC score	0.050287 (rank : 107)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	23	Target Neighborhood Hits	341	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB9_HUMAN
NC score	0.050284 (rank : 108)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	23	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CJ120_HUMAN
NC score	0.044955 (rank : 109)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SQS8	Gene names	C10orf120
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf120.

SNX24_HUMAN
NC score	0.021606 (rank : 110)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y343, Q6UY33	Gene names	SNX24
Domain Architecture
Description	Sorting nexin-24.

CD2L7_HUMAN
NC score	0.011546 (rank : 111)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	1275	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).