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PEA15_HUMAN
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| SwissProt Accessions | Q15121, O00511 | Gene names | PEA15 | |||
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Domain Architecture |
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| Description | Astrocytic phosphoprotein PEA-15 (Phosphoprotein enriched in diabetes) (PED). | |||||
| Rank Plots |
Jump to hits sorted by NC score
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PEA15_HUMAN
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| θ value | 9.11921e-69 (rank : 1) | NC score | 0.999962 (rank : 1) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 10 | Shared Neighborhood Hits | 10 | |
| SwissProt Accessions | Q15121, O00511 | Gene names | PEA15 | |||
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Domain Architecture |
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| Description | Astrocytic phosphoprotein PEA-15 (Phosphoprotein enriched in diabetes) (PED). | |||||
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PEA15_MOUSE
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| θ value | 2.65329e-68 (rank : 2) | NC score | 0.999258 (rank : 2) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 7 | Shared Neighborhood Hits | 7 | |
| SwissProt Accessions | Q62048, Q3U5N7 | Gene names | Pea15 | |||
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Domain Architecture |
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| Description | Astrocytic phosphoprotein PEA-15. | |||||
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FADD_MOUSE
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| θ value | 0.00020696 (rank : 3) | NC score | 0.319637 (rank : 3) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 23 | Shared Neighborhood Hits | 6 | |
| SwissProt Accessions | Q61160, Q3TC37, Q61082 | Gene names | Fadd, Mort1 | |||
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Domain Architecture |
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| Description | FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity). | |||||
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CASP8_HUMAN
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| θ value | 0.00228821 (rank : 4) | NC score | 0.198081 (rank : 4) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 62 | Shared Neighborhood Hits | 6 | |
| SwissProt Accessions | Q14790, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81 | Gene names | CASP8, MCH5 | |||
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Domain Architecture |
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| Description | Caspase-8 precursor (EC 3.4.22.-) (CASP-8) (ICE-like apoptotic protease 5) (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous ICE/CED-3-like protease) (FADD-like ICE) (FLICE) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10]. | |||||
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CASP8_MOUSE
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| θ value | 0.00665767 (rank : 5) | NC score | 0.187715 (rank : 5) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 57 | Shared Neighborhood Hits | 6 | |
| SwissProt Accessions | O89110, O35669 | Gene names | Casp8 | |||
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Domain Architecture |
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| Description | Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10]. | |||||
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CASPA_HUMAN
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| θ value | 0.0961366 (rank : 6) | NC score | 0.163259 (rank : 6) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 53 | Shared Neighborhood Hits | 6 | |
| SwissProt Accessions | Q92851, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7 | Gene names | CASP10, MCH4 | |||
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Domain Architecture |
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| Description | Caspase-10 precursor (EC 3.4.22.-) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12]. | |||||
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ACTN1_HUMAN
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| θ value | 5.27518 (rank : 7) | NC score | 0.017090 (rank : 22) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 221 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | P12814, Q9BTN1 | Gene names | ACTN1 | |||
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Domain Architecture |
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| Description | Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein). | |||||
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SGT1_HUMAN
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| θ value | 5.27518 (rank : 8) | NC score | 0.045142 (rank : 21) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 18 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | O95905 | Gene names | ECD, SGT1 | |||
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Domain Architecture |
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| Description | SGT1 protein (hSGT1) (Ecdysoneless homolog) (Suppressor of GCR2). | |||||
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ACTN3_HUMAN
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| θ value | 8.99809 (rank : 9) | NC score | 0.016066 (rank : 23) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 272 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | Q08043 | Gene names | ACTN3 | |||
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Domain Architecture |
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| Description | Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein). | |||||
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ACTN3_MOUSE
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| θ value | 8.99809 (rank : 10) | NC score | 0.015995 (rank : 24) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 265 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | O88990 | Gene names | Actn3 | |||
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Domain Architecture |
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| Description | Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein). | |||||
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CASP2_HUMAN
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| θ value | θ > 10 (rank : 11) | NC score | 0.058470 (rank : 18) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 31 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P42575, P42576, Q59F21, Q7KZL6, Q86UJ3, Q9BUP7, Q9BZK9 | Gene names | CASP2, ICH1 | |||
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Domain Architecture |
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| Description | Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (ICH- 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]. | |||||
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CASP2_MOUSE
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| θ value | θ > 10 (rank : 12) | NC score | 0.057473 (rank : 19) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 34 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P29594, O08737, Q3TCM0, Q8C9H7, Q8K241 | Gene names | Casp2, Ich1, Nedd-2, Nedd2 | |||
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Domain Architecture |
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| Description | Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural precursor cell expressed developmentally down- regulated protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]. | |||||
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CASP3_HUMAN
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| θ value | θ > 10 (rank : 13) | NC score | 0.065023 (rank : 15) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 27 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P42574, Q96AN1, Q96KP2 | Gene names | CASP3, CPP32 | |||
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Domain Architecture |
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| Description | Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit]. | |||||
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CASP3_MOUSE
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| θ value | θ > 10 (rank : 14) | NC score | 0.065748 (rank : 13) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 23 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P70677, O08668, Q8CHV5, Q9QWI4 | Gene names | Casp3, Cpp32 | |||
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Domain Architecture |
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| Description | Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) (LICE) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit]. | |||||
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CASP6_HUMAN
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| θ value | θ > 10 (rank : 15) | NC score | 0.064706 (rank : 16) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 24 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P55212, Q9BQE7 | Gene names | CASP6, MCH2 | |||
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Domain Architecture |
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| Description | Caspase-6 precursor (EC 3.4.22.-) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11]. | |||||
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CASP6_MOUSE
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| θ value | θ > 10 (rank : 16) | NC score | 0.065272 (rank : 14) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 24 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | O08738 | Gene names | Casp6 | |||
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Domain Architecture |
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| Description | Caspase-6 precursor (EC 3.4.22.-) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11]. | |||||
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CASP7_HUMAN
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| θ value | θ > 10 (rank : 17) | NC score | 0.069792 (rank : 11) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 26 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P55210, Q13364, Q96BA0 | Gene names | CASP7, MCH3 | |||
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Domain Architecture |
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| Description | Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3) (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11]. | |||||
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CASP7_MOUSE
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| θ value | θ > 10 (rank : 18) | NC score | 0.071350 (rank : 10) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 24 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P97864, O08669 | Gene names | Casp7, Lice2, Mch3 | |||
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Domain Architecture |
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| Description | Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (LICE2 cysteine protease) (Apoptotic protease Mch-3) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11]. | |||||
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CASP9_HUMAN
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| θ value | θ > 10 (rank : 19) | NC score | 0.068624 (rank : 12) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 33 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P55211, O95348, Q92852, Q9BQ62, Q9UEQ3, Q9UIJ8 | Gene names | CASP9, MCH6 | |||
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Domain Architecture |
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| Description | Caspase-9 precursor (EC 3.4.22.-) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease- activating factor 3) (APAF-3) [Contains: Caspase-9 subunit p35; Caspase-9 subunit p10]. | |||||
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CASPE_HUMAN
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| θ value | θ > 10 (rank : 20) | NC score | 0.058500 (rank : 17) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 26 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P31944, O95823, Q3SYC9 | Gene names | CASP14 | |||
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Domain Architecture |
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| Description | Caspase-14 precursor (EC 3.4.22.-) (CASP-14) [Contains: Caspase-14 subunit 1; Caspase-14 subunit 2]. | |||||
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CASPE_MOUSE
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| θ value | θ > 10 (rank : 21) | NC score | 0.056367 (rank : 20) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 23 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | O89094 | Gene names | Casp14 | |||
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Domain Architecture |
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| Description | Caspase-14 precursor (EC 3.4.22.-) (CASP-14) (Mini-ICE) (MICE) [Contains: Caspase-14 subunit 1; Caspase-14 subunit 2]. | |||||
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CFLAR_HUMAN
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| θ value | θ > 10 (rank : 22) | NC score | 0.082262 (rank : 8) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 47 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | O15519, O14673, O14674, O14675, O15137, O15138, O15356, O15510, O43618, O43619, O43620, O60458, O60459, Q96TE4, Q9UEW1 | Gene names | CFLAR, CASH, CLARP, MRIT | |||
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Domain Architecture |
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| Description | CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin) [Contains: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]. | |||||
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CFLAR_MOUSE
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| θ value | θ > 10 (rank : 23) | NC score | 0.077796 (rank : 9) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 32 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | O35732, O35707, O35733 | Gene names | Cflar, Cash | |||
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Domain Architecture |
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| Description | CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin) [Contains: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]. | |||||
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FADD_HUMAN
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| θ value | θ > 10 (rank : 24) | NC score | 0.137249 (rank : 7) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 20 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | Q13158, Q14866 | Gene names | FADD, MORT1 | |||
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Domain Architecture |
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| Description | FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity). | |||||
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PEA15_HUMAN
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| NC score | 0.999962 (rank : 1) | θ value | 9.11921e-69 (rank : 1) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 10 | Shared Neighborhood Hits | 10 | |
| SwissProt Accessions | Q15121, O00511 | Gene names | PEA15 | |||
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Domain Architecture |
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| Description | Astrocytic phosphoprotein PEA-15 (Phosphoprotein enriched in diabetes) (PED). | |||||
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PEA15_MOUSE
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| NC score | 0.999258 (rank : 2) | θ value | 2.65329e-68 (rank : 2) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 7 | Shared Neighborhood Hits | 7 | |
| SwissProt Accessions | Q62048, Q3U5N7 | Gene names | Pea15 | |||
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Domain Architecture |
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| Description | Astrocytic phosphoprotein PEA-15. | |||||
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FADD_MOUSE
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| NC score | 0.319637 (rank : 3) | θ value | 0.00020696 (rank : 3) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 23 | Shared Neighborhood Hits | 6 | |
| SwissProt Accessions | Q61160, Q3TC37, Q61082 | Gene names | Fadd, Mort1 | |||
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Domain Architecture |
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| Description | FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity). | |||||
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CASP8_HUMAN
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| NC score | 0.198081 (rank : 4) | θ value | 0.00228821 (rank : 4) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 62 | Shared Neighborhood Hits | 6 | |
| SwissProt Accessions | Q14790, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81 | Gene names | CASP8, MCH5 | |||
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Domain Architecture |
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| Description | Caspase-8 precursor (EC 3.4.22.-) (CASP-8) (ICE-like apoptotic protease 5) (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous ICE/CED-3-like protease) (FADD-like ICE) (FLICE) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10]. | |||||
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CASP8_MOUSE
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| NC score | 0.187715 (rank : 5) | θ value | 0.00665767 (rank : 5) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 57 | Shared Neighborhood Hits | 6 | |
| SwissProt Accessions | O89110, O35669 | Gene names | Casp8 | |||
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Domain Architecture |
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| Description | Caspase-8 precursor (EC 3.4.22.-) (CASP-8) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10]. | |||||
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CASPA_HUMAN
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| NC score | 0.163259 (rank : 6) | θ value | 0.0961366 (rank : 6) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 53 | Shared Neighborhood Hits | 6 | |
| SwissProt Accessions | Q92851, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7 | Gene names | CASP10, MCH4 | |||
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Domain Architecture |
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| Description | Caspase-10 precursor (EC 3.4.22.-) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12]. | |||||
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FADD_HUMAN
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| NC score | 0.137249 (rank : 7) | θ value | θ > 10 (rank : 24) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 20 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | Q13158, Q14866 | Gene names | FADD, MORT1 | |||
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Domain Architecture |
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| Description | FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity). | |||||
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CFLAR_HUMAN
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| NC score | 0.082262 (rank : 8) | θ value | θ > 10 (rank : 22) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 47 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | O15519, O14673, O14674, O14675, O15137, O15138, O15356, O15510, O43618, O43619, O43620, O60458, O60459, Q96TE4, Q9UEW1 | Gene names | CFLAR, CASH, CLARP, MRIT | |||
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Domain Architecture |
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| Description | CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin) [Contains: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]. | |||||
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CFLAR_MOUSE
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| NC score | 0.077796 (rank : 9) | θ value | θ > 10 (rank : 23) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 32 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | O35732, O35707, O35733 | Gene names | Cflar, Cash | |||
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Domain Architecture |
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| Description | CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Usurpin) [Contains: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]. | |||||
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CASP7_MOUSE
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| NC score | 0.071350 (rank : 10) | θ value | θ > 10 (rank : 18) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 24 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P97864, O08669 | Gene names | Casp7, Lice2, Mch3 | |||
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Domain Architecture |
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| Description | Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (LICE2 cysteine protease) (Apoptotic protease Mch-3) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11]. | |||||
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CASP7_HUMAN
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| NC score | 0.069792 (rank : 11) | θ value | θ > 10 (rank : 17) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 26 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P55210, Q13364, Q96BA0 | Gene names | CASP7, MCH3 | |||
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Domain Architecture |
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| Description | Caspase-7 precursor (EC 3.4.22.-) (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3) (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11]. | |||||
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CASP9_HUMAN
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| NC score | 0.068624 (rank : 12) | θ value | θ > 10 (rank : 19) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 33 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P55211, O95348, Q92852, Q9BQ62, Q9UEQ3, Q9UIJ8 | Gene names | CASP9, MCH6 | |||
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Domain Architecture |
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| Description | Caspase-9 precursor (EC 3.4.22.-) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease- activating factor 3) (APAF-3) [Contains: Caspase-9 subunit p35; Caspase-9 subunit p10]. | |||||
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CASP3_MOUSE
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| NC score | 0.065748 (rank : 13) | θ value | θ > 10 (rank : 14) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 23 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P70677, O08668, Q8CHV5, Q9QWI4 | Gene names | Casp3, Cpp32 | |||
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Domain Architecture |
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| Description | Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) (LICE) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit]. | |||||
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CASP6_MOUSE
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| NC score | 0.065272 (rank : 14) | θ value | θ > 10 (rank : 16) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 24 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | O08738 | Gene names | Casp6 | |||
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Domain Architecture |
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| Description | Caspase-6 precursor (EC 3.4.22.-) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11]. | |||||
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CASP3_HUMAN
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| NC score | 0.065023 (rank : 15) | θ value | θ > 10 (rank : 13) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 27 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P42574, Q96AN1, Q96KP2 | Gene names | CASP3, CPP32 | |||
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Domain Architecture |
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| Description | Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit]. | |||||
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CASP6_HUMAN
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| NC score | 0.064706 (rank : 16) | θ value | θ > 10 (rank : 15) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 24 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P55212, Q9BQE7 | Gene names | CASP6, MCH2 | |||
|
Domain Architecture |
|
|||||
| Description | Caspase-6 precursor (EC 3.4.22.-) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11]. | |||||
|
CASPE_HUMAN
|
||||||
| NC score | 0.058500 (rank : 17) | θ value | θ > 10 (rank : 20) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 26 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P31944, O95823, Q3SYC9 | Gene names | CASP14 | |||
|
Domain Architecture |
|
|||||
| Description | Caspase-14 precursor (EC 3.4.22.-) (CASP-14) [Contains: Caspase-14 subunit 1; Caspase-14 subunit 2]. | |||||
|
CASP2_HUMAN
|
||||||
| NC score | 0.058470 (rank : 18) | θ value | θ > 10 (rank : 11) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 31 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P42575, P42576, Q59F21, Q7KZL6, Q86UJ3, Q9BUP7, Q9BZK9 | Gene names | CASP2, ICH1 | |||
|
Domain Architecture |
|
|||||
| Description | Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (ICH- 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]. | |||||
|
CASP2_MOUSE
|
||||||
| NC score | 0.057473 (rank : 19) | θ value | θ > 10 (rank : 12) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 34 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | P29594, O08737, Q3TCM0, Q8C9H7, Q8K241 | Gene names | Casp2, Ich1, Nedd-2, Nedd2 | |||
|
Domain Architecture |
|
|||||
| Description | Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural precursor cell expressed developmentally down- regulated protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]. | |||||
|
CASPE_MOUSE
|
||||||
| NC score | 0.056367 (rank : 20) | θ value | θ > 10 (rank : 21) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 23 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | O89094 | Gene names | Casp14 | |||
|
Domain Architecture |
|
|||||
| Description | Caspase-14 precursor (EC 3.4.22.-) (CASP-14) (Mini-ICE) (MICE) [Contains: Caspase-14 subunit 1; Caspase-14 subunit 2]. | |||||
|
SGT1_HUMAN
|
||||||
| NC score | 0.045142 (rank : 21) | θ value | 5.27518 (rank : 8) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 18 | Shared Neighborhood Hits | 3 | |
| SwissProt Accessions | O95905 | Gene names | ECD, SGT1 | |||
|
Domain Architecture |
|
|||||
| Description | SGT1 protein (hSGT1) (Ecdysoneless homolog) (Suppressor of GCR2). | |||||
|
ACTN1_HUMAN
|
||||||
| NC score | 0.017090 (rank : 22) | θ value | 5.27518 (rank : 7) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 221 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | P12814, Q9BTN1 | Gene names | ACTN1 | |||
|
Domain Architecture |
|
|||||
| Description | Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein). | |||||
|
ACTN3_HUMAN
|
||||||
| NC score | 0.016066 (rank : 23) | θ value | 8.99809 (rank : 9) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 272 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | Q08043 | Gene names | ACTN3 | |||
|
Domain Architecture |
|
|||||
| Description | Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein). | |||||
|
ACTN3_MOUSE
|
||||||
| NC score | 0.015995 (rank : 24) | θ value | 8.99809 (rank : 10) | |||
| Query Neighborhood Hits | 10 | Target Neighborhood Hits | 265 | Shared Neighborhood Hits | 4 | |
| SwissProt Accessions | O88990 | Gene names | Actn3 | |||
|
Domain Architecture |
|
|||||
| Description | Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein). | |||||
