Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : INVS_HUMAN

For an explanation of this page, click here

INVS_HUMAN
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

INVS_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	455
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	0 (rank : 2)	NC score	0.981358 (rank : 2)
Query Neighborhood Hits	455	Target Neighborhood Hits	609	Shared Neighborhood Hits	356
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR44_HUMAN
θ value	3.0428e-56 (rank : 3)	NC score	0.948816 (rank : 4)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	296
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANK2_HUMAN
θ value	8.28633e-54 (rank : 4)	NC score	0.873553 (rank : 69)
Query Neighborhood Hits	455	Target Neighborhood Hits	1615	Shared Neighborhood Hits	381
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR50_HUMAN
θ value	2.41096e-53 (rank : 5)	NC score	0.952126 (rank : 3)
Query Neighborhood Hits	455	Target Neighborhood Hits	361	Shared Neighborhood Hits	297
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR52_HUMAN
θ value	1.32293e-51 (rank : 6)	NC score	0.939845 (rank : 7)
Query Neighborhood Hits	455	Target Neighborhood Hits	322	Shared Neighborhood Hits	296
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR28_MOUSE
θ value	2.75849e-49 (rank : 7)	NC score	0.944648 (rank : 5)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	296
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
θ value	1.788e-48 (rank : 8)	NC score	0.944091 (rank : 6)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK1_HUMAN
θ value	2.3352e-48 (rank : 9)	NC score	0.932290 (rank : 13)
Query Neighborhood Hits	455	Target Neighborhood Hits	416	Shared Neighborhood Hits	302
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK3_HUMAN
θ value	3.98324e-48 (rank : 10)	NC score	0.920632 (rank : 20)
Query Neighborhood Hits	455	Target Neighborhood Hits	853	Shared Neighborhood Hits	326
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANK1_MOUSE
θ value	7.51208e-47 (rank : 11)	NC score	0.930230 (rank : 14)
Query Neighborhood Hits	455	Target Neighborhood Hits	430	Shared Neighborhood Hits	299
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR52_MOUSE
θ value	1.01529e-43 (rank : 12)	NC score	0.937826 (rank : 8)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	296
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANKK1_HUMAN
θ value	3.16345e-37 (rank : 13)	NC score	0.603394 (rank : 204)
Query Neighborhood Hits	455	Target Neighborhood Hits	1075	Shared Neighborhood Hits	301
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

TNKS1_HUMAN
θ value	5.96599e-36 (rank : 14)	NC score	0.924014 (rank : 16)
Query Neighborhood Hits	455	Target Neighborhood Hits	477	Shared Neighborhood Hits	309
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANKK1_MOUSE
θ value	9.52487e-34 (rank : 15)	NC score	0.587591 (rank : 210)
Query Neighborhood Hits	455	Target Neighborhood Hits	1072	Shared Neighborhood Hits	301
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

RIPK4_HUMAN
θ value	9.52487e-34 (rank : 16)	NC score	0.594016 (rank : 208)
Query Neighborhood Hits	455	Target Neighborhood Hits	1094	Shared Neighborhood Hits	309
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

TNKS2_HUMAN
θ value	1.79631e-32 (rank : 17)	NC score	0.922942 (rank : 17)
Query Neighborhood Hits	455	Target Neighborhood Hits	361	Shared Neighborhood Hits	295
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

DAPK1_HUMAN
θ value	4.14116e-29 (rank : 18)	NC score	0.418727 (rank : 260)
Query Neighborhood Hits	455	Target Neighborhood Hits	1130	Shared Neighborhood Hits	303
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_MOUSE
θ value	1.57365e-28 (rank : 19)	NC score	0.427798 (rank : 257)
Query Neighborhood Hits	455	Target Neighborhood Hits	1138	Shared Neighborhood Hits	306
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TRPA1_HUMAN
θ value	2.05525e-28 (rank : 20)	NC score	0.913580 (rank : 26)
Query Neighborhood Hits	455	Target Neighborhood Hits	339	Shared Neighborhood Hits	293
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

TRPA1_MOUSE
θ value	2.68423e-28 (rank : 21)	NC score	0.914127 (rank : 25)
Query Neighborhood Hits	455	Target Neighborhood Hits	343	Shared Neighborhood Hits	290
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

EHMT2_MOUSE
θ value	1.24688e-25 (rank : 22)	NC score	0.836877 (rank : 121)
Query Neighborhood Hits	455	Target Neighborhood Hits	750	Shared Neighborhood Hits	339
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANFY1_MOUSE
θ value	1.62847e-25 (rank : 23)	NC score	0.829984 (rank : 126)
Query Neighborhood Hits	455	Target Neighborhood Hits	480	Shared Neighborhood Hits	289
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB15_HUMAN
θ value	3.62785e-25 (rank : 24)	NC score	0.893567 (rank : 44)
Query Neighborhood Hits	455	Target Neighborhood Hits	305	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

EHMT2_HUMAN
θ value	1.37858e-24 (rank : 25)	NC score	0.849051 (rank : 107)
Query Neighborhood Hits	455	Target Neighborhood Hits	498	Shared Neighborhood Hits	303
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

CSKI1_HUMAN
θ value	1.80048e-24 (rank : 26)	NC score	0.850967 (rank : 100)
Query Neighborhood Hits	455	Target Neighborhood Hits	997	Shared Neighborhood Hits	337
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	2.35151e-24 (rank : 27)	NC score	0.849085 (rank : 106)
Query Neighborhood Hits	455	Target Neighborhood Hits	1031	Shared Neighborhood Hits	327
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RAI14_MOUSE
θ value	5.23862e-24 (rank : 28)	NC score	0.648378 (rank : 194)
Query Neighborhood Hits	455	Target Neighborhood Hits	1505	Shared Neighborhood Hits	325
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANKS1_HUMAN
θ value	1.5242e-23 (rank : 29)	NC score	0.882641 (rank : 51)
Query Neighborhood Hits	455	Target Neighborhood Hits	438	Shared Neighborhood Hits	293
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

EHMT1_HUMAN
θ value	1.5242e-23 (rank : 30)	NC score	0.859057 (rank : 88)
Query Neighborhood Hits	455	Target Neighborhood Hits	417	Shared Neighborhood Hits	301
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ASB15_MOUSE
θ value	1.99067e-23 (rank : 31)	NC score	0.882479 (rank : 52)
Query Neighborhood Hits	455	Target Neighborhood Hits	292	Shared Neighborhood Hits	270
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MIB2_MOUSE
θ value	2.59989e-23 (rank : 32)	NC score	0.872466 (rank : 73)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	282
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MIB2_HUMAN
θ value	4.43474e-23 (rank : 33)	NC score	0.872608 (rank : 72)
Query Neighborhood Hits	455	Target Neighborhood Hits	438	Shared Neighborhood Hits	290
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ASB3_MOUSE
θ value	9.87957e-23 (rank : 34)	NC score	0.922872 (rank : 18)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	292
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANKS1_MOUSE
θ value	1.29031e-22 (rank : 35)	NC score	0.871560 (rank : 75)
Query Neighborhood Hits	455	Target Neighborhood Hits	453	Shared Neighborhood Hits	294
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

RAI14_HUMAN
θ value	3.75424e-22 (rank : 36)	NC score	0.682338 (rank : 189)
Query Neighborhood Hits	455	Target Neighborhood Hits	1367	Shared Neighborhood Hits	314
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ASB10_HUMAN
θ value	1.09232e-21 (rank : 37)	NC score	0.912218 (rank : 27)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

MIB1_HUMAN
θ value	1.09232e-21 (rank : 38)	NC score	0.877107 (rank : 63)
Query Neighborhood Hits	455	Target Neighborhood Hits	470	Shared Neighborhood Hits	291
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	1.09232e-21 (rank : 39)	NC score	0.876722 (rank : 64)
Query Neighborhood Hits	455	Target Neighborhood Hits	471	Shared Neighborhood Hits	291
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ASB10_MOUSE
θ value	1.42661e-21 (rank : 40)	NC score	0.911275 (rank : 29)
Query Neighborhood Hits	455	Target Neighborhood Hits	301	Shared Neighborhood Hits	284
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

TNI3K_HUMAN
θ value	1.42661e-21 (rank : 41)	NC score	0.469574 (rank : 248)
Query Neighborhood Hits	455	Target Neighborhood Hits	1084	Shared Neighborhood Hits	305
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
θ value	1.42661e-21 (rank : 42)	NC score	0.464048 (rank : 249)
Query Neighborhood Hits	455	Target Neighborhood Hits	1079	Shared Neighborhood Hits	303
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANFY1_HUMAN
θ value	1.86321e-21 (rank : 43)	NC score	0.827399 (rank : 128)
Query Neighborhood Hits	455	Target Neighborhood Hits	480	Shared Neighborhood Hits	286
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB3_HUMAN
θ value	1.86321e-21 (rank : 44)	NC score	0.922678 (rank : 19)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR29_HUMAN
θ value	4.15078e-21 (rank : 45)	NC score	0.937627 (rank : 9)
Query Neighborhood Hits	455	Target Neighborhood Hits	294	Shared Neighborhood Hits	289
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
θ value	5.42112e-21 (rank : 46)	NC score	0.934178 (rank : 10)
Query Neighborhood Hits	455	Target Neighborhood Hits	301	Shared Neighborhood Hits	290
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
θ value	2.69047e-20 (rank : 47)	NC score	0.932812 (rank : 12)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	288
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ASB2_HUMAN
θ value	3.51386e-20 (rank : 48)	NC score	0.909621 (rank : 30)
Query Neighborhood Hits	455	Target Neighborhood Hits	309	Shared Neighborhood Hits	286
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

FANK1_MOUSE
θ value	1.02238e-19 (rank : 49)	NC score	0.918672 (rank : 22)
Query Neighborhood Hits	455	Target Neighborhood Hits	325	Shared Neighborhood Hits	284
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANKR6_HUMAN
θ value	2.27762e-19 (rank : 50)	NC score	0.925128 (rank : 15)
Query Neighborhood Hits	455	Target Neighborhood Hits	439	Shared Neighborhood Hits	301
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR16_HUMAN
θ value	2.27762e-19 (rank : 51)	NC score	0.933171 (rank : 11)
Query Neighborhood Hits	455	Target Neighborhood Hits	286	Shared Neighborhood Hits	280
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR35_HUMAN
θ value	6.62687e-19 (rank : 52)	NC score	0.841400 (rank : 117)
Query Neighborhood Hits	455	Target Neighborhood Hits	784	Shared Neighborhood Hits	297
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ANR42_MOUSE
θ value	6.62687e-19 (rank : 53)	NC score	0.911977 (rank : 28)
Query Neighborhood Hits	455	Target Neighborhood Hits	334	Shared Neighborhood Hits	282
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

UACA_HUMAN
θ value	8.65492e-19 (rank : 54)	NC score	0.541420 (rank : 223)
Query Neighborhood Hits	455	Target Neighborhood Hits	1622	Shared Neighborhood Hits	301
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

FANK1_HUMAN
θ value	1.47631e-18 (rank : 55)	NC score	0.919416 (rank : 21)
Query Neighborhood Hits	455	Target Neighborhood Hits	326	Shared Neighborhood Hits	286
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ASB7_MOUSE
θ value	2.5182e-18 (rank : 56)	NC score	0.915183 (rank : 23)
Query Neighborhood Hits	455	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

CSKI2_MOUSE
θ value	2.5182e-18 (rank : 57)	NC score	0.852322 (rank : 98)
Query Neighborhood Hits	455	Target Neighborhood Hits	812	Shared Neighborhood Hits	322
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB7_HUMAN
θ value	3.28887e-18 (rank : 58)	NC score	0.914906 (rank : 24)
Query Neighborhood Hits	455	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

CSKI2_HUMAN
θ value	4.29542e-18 (rank : 59)	NC score	0.850711 (rank : 101)
Query Neighborhood Hits	455	Target Neighborhood Hits	747	Shared Neighborhood Hits	312
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB14_MOUSE
θ value	5.60996e-18 (rank : 60)	NC score	0.881472 (rank : 55)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANKR1_MOUSE
θ value	7.32683e-18 (rank : 61)	NC score	0.899561 (rank : 40)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	284
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANR23_HUMAN
θ value	9.56915e-18 (rank : 62)	NC score	0.908449 (rank : 32)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	284
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR23_MOUSE
θ value	3.63628e-17 (rank : 63)	NC score	0.908475 (rank : 31)
Query Neighborhood Hits	455	Target Neighborhood Hits	296	Shared Neighborhood Hits	285
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

UACA_MOUSE
θ value	4.74913e-17 (rank : 64)	NC score	0.514138 (rank : 235)
Query Neighborhood Hits	455	Target Neighborhood Hits	1620	Shared Neighborhood Hits	299
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANKR1_HUMAN
θ value	6.20254e-17 (rank : 65)	NC score	0.900875 (rank : 37)
Query Neighborhood Hits	455	Target Neighborhood Hits	308	Shared Neighborhood Hits	279
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR2_MOUSE
θ value	8.10077e-17 (rank : 66)	NC score	0.907833 (rank : 33)
Query Neighborhood Hits	455	Target Neighborhood Hits	312	Shared Neighborhood Hits	286
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR2_HUMAN
θ value	1.058e-16 (rank : 67)	NC score	0.906966 (rank : 34)
Query Neighborhood Hits	455	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

NOTC1_HUMAN
θ value	1.058e-16 (rank : 68)	NC score	0.440507 (rank : 253)
Query Neighborhood Hits	455	Target Neighborhood Hits	906	Shared Neighborhood Hits	285
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANR21_HUMAN
θ value	1.80466e-16 (rank : 69)	NC score	0.785887 (rank : 145)
Query Neighborhood Hits	455	Target Neighborhood Hits	864	Shared Neighborhood Hits	302
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANKS6_HUMAN
θ value	3.07829e-16 (rank : 70)	NC score	0.884785 (rank : 48)
Query Neighborhood Hits	455	Target Neighborhood Hits	411	Shared Neighborhood Hits	302
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CTTB2_HUMAN
θ value	3.07829e-16 (rank : 71)	NC score	0.780451 (rank : 150)
Query Neighborhood Hits	455	Target Neighborhood Hits	1061	Shared Neighborhood Hits	306
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ZDH17_HUMAN
θ value	4.02038e-16 (rank : 72)	NC score	0.796949 (rank : 139)
Query Neighborhood Hits	455	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ZDH17_MOUSE
θ value	6.85773e-16 (rank : 73)	NC score	0.791949 (rank : 141)
Query Neighborhood Hits	455	Target Neighborhood Hits	328	Shared Neighborhood Hits	275
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ASB13_HUMAN
θ value	8.95645e-16 (rank : 74)	NC score	0.899173 (rank : 42)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	285
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	8.95645e-16 (rank : 75)	NC score	0.899505 (rank : 41)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

POT15_HUMAN
θ value	1.52774e-15 (rank : 76)	NC score	0.786008 (rank : 144)
Query Neighborhood Hits	455	Target Neighborhood Hits	893	Shared Neighborhood Hits	301
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

RN5A_MOUSE
θ value	1.52774e-15 (rank : 77)	NC score	0.802108 (rank : 135)
Query Neighborhood Hits	455	Target Neighborhood Hits	899	Shared Neighborhood Hits	297
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

BCL3_HUMAN
θ value	1.99529e-15 (rank : 78)	NC score	0.891029 (rank : 46)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	282
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

BCL3_MOUSE
θ value	2.60593e-15 (rank : 79)	NC score	0.885968 (rank : 47)
Query Neighborhood Hits	455	Target Neighborhood Hits	388	Shared Neighborhood Hits	289
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ASB9_HUMAN
θ value	4.44505e-15 (rank : 80)	NC score	0.866494 (rank : 79)
Query Neighborhood Hits	455	Target Neighborhood Hits	267	Shared Neighborhood Hits	257
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ANKS6_MOUSE
θ value	5.8054e-15 (rank : 81)	NC score	0.884400 (rank : 49)
Query Neighborhood Hits	455	Target Neighborhood Hits	435	Shared Neighborhood Hits	300
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR18_HUMAN
θ value	7.58209e-15 (rank : 82)	NC score	0.665792 (rank : 192)
Query Neighborhood Hits	455	Target Neighborhood Hits	1106	Shared Neighborhood Hits	283
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR42_HUMAN
θ value	7.58209e-15 (rank : 83)	NC score	0.905950 (rank : 35)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

PA2G6_HUMAN
θ value	9.90251e-15 (rank : 84)	NC score	0.880092 (rank : 58)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB11_HUMAN
θ value	1.29331e-14 (rank : 85)	NC score	0.863027 (rank : 82)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANKR5_HUMAN
θ value	2.20605e-14 (rank : 86)	NC score	0.877800 (rank : 61)
Query Neighborhood Hits	455	Target Neighborhood Hits	297	Shared Neighborhood Hits	283
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB2_MOUSE
θ value	2.88119e-14 (rank : 87)	NC score	0.900713 (rank : 39)
Query Neighborhood Hits	455	Target Neighborhood Hits	321	Shared Neighborhood Hits	283
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

NOTC2_HUMAN
θ value	2.88119e-14 (rank : 88)	NC score	0.437792 (rank : 255)
Query Neighborhood Hits	455	Target Neighborhood Hits	1113	Shared Neighborhood Hits	302
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ASB8_MOUSE
θ value	3.76295e-14 (rank : 89)	NC score	0.901304 (rank : 36)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

MYPT1_HUMAN
θ value	4.91457e-14 (rank : 90)	NC score	0.839124 (rank : 119)
Query Neighborhood Hits	455	Target Neighborhood Hits	723	Shared Neighborhood Hits	291
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	4.91457e-14 (rank : 91)	NC score	0.860070 (rank : 86)
Query Neighborhood Hits	455	Target Neighborhood Hits	539	Shared Neighborhood Hits	297
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

NOTC2_MOUSE
θ value	6.41864e-14 (rank : 92)	NC score	0.435000 (rank : 256)
Query Neighborhood Hits	455	Target Neighborhood Hits	1069	Shared Neighborhood Hits	295
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ASB5_HUMAN
θ value	8.38298e-14 (rank : 93)	NC score	0.861474 (rank : 85)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	270
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB8_HUMAN
θ value	8.38298e-14 (rank : 94)	NC score	0.900794 (rank : 38)
Query Neighborhood Hits	455	Target Neighborhood Hits	294	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASZ1_MOUSE
θ value	8.38298e-14 (rank : 95)	NC score	0.872990 (rank : 70)
Query Neighborhood Hits	455	Target Neighborhood Hits	319	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ZDH13_HUMAN
θ value	1.09485e-13 (rank : 96)	NC score	0.789307 (rank : 142)
Query Neighborhood Hits	455	Target Neighborhood Hits	322	Shared Neighborhood Hits	274
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ASZ1_HUMAN
θ value	1.42992e-13 (rank : 97)	NC score	0.871615 (rank : 74)
Query Neighborhood Hits	455	Target Neighborhood Hits	341	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

A20A1_HUMAN
θ value	1.86753e-13 (rank : 98)	NC score	0.718622 (rank : 178)
Query Neighborhood Hits	455	Target Neighborhood Hits	698	Shared Neighborhood Hits	276
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A3_HUMAN
θ value	1.86753e-13 (rank : 99)	NC score	0.721047 (rank : 174)
Query Neighborhood Hits	455	Target Neighborhood Hits	692	Shared Neighborhood Hits	280
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	1.86753e-13 (rank : 100)	NC score	0.715878 (rank : 180)
Query Neighborhood Hits	455	Target Neighborhood Hits	710	Shared Neighborhood Hits	280
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

RN5A_HUMAN
θ value	1.86753e-13 (rank : 101)	NC score	0.852726 (rank : 97)
Query Neighborhood Hits	455	Target Neighborhood Hits	608	Shared Neighborhood Hits	282
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ZDH13_MOUSE
θ value	1.86753e-13 (rank : 102)	NC score	0.785353 (rank : 147)
Query Neighborhood Hits	455	Target Neighborhood Hits	329	Shared Neighborhood Hits	277
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

A20A2_HUMAN
θ value	2.43908e-13 (rank : 103)	NC score	0.720062 (rank : 175)
Query Neighborhood Hits	455	Target Neighborhood Hits	716	Shared Neighborhood Hits	280
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANKR5_MOUSE
θ value	2.43908e-13 (rank : 104)	NC score	0.875240 (rank : 65)
Query Neighborhood Hits	455	Target Neighborhood Hits	298	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR7_HUMAN
θ value	2.43908e-13 (rank : 105)	NC score	0.882343 (rank : 53)
Query Neighborhood Hits	455	Target Neighborhood Hits	286	Shared Neighborhood Hits	277
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANKS3_MOUSE
θ value	3.18553e-13 (rank : 106)	NC score	0.880600 (rank : 57)
Query Neighborhood Hits	455	Target Neighborhood Hits	355	Shared Neighborhood Hits	278
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB12_HUMAN
θ value	3.18553e-13 (rank : 107)	NC score	0.854117 (rank : 95)
Query Neighborhood Hits	455	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

NOTC1_MOUSE
θ value	3.18553e-13 (rank : 108)	NC score	0.377403 (rank : 266)
Query Neighborhood Hits	455	Target Neighborhood Hits	916	Shared Neighborhood Hits	264
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
θ value	3.18553e-13 (rank : 109)	NC score	0.439965 (rank : 254)
Query Neighborhood Hits	455	Target Neighborhood Hits	1062	Shared Neighborhood Hits	295
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	3.18553e-13 (rank : 110)	NC score	0.442234 (rank : 252)
Query Neighborhood Hits	455	Target Neighborhood Hits	975	Shared Neighborhood Hits	290
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PA2G6_MOUSE
θ value	3.18553e-13 (rank : 111)	NC score	0.881168 (rank : 56)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANRA2_MOUSE
θ value	4.16044e-13 (rank : 112)	NC score	0.866898 (rank : 78)
Query Neighborhood Hits	455	Target Neighborhood Hits	287	Shared Neighborhood Hits	277
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR26_HUMAN
θ value	7.09661e-13 (rank : 113)	NC score	0.475934 (rank : 245)
Query Neighborhood Hits	455	Target Neighborhood Hits	1614	Shared Neighborhood Hits	306
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANRA2_HUMAN
θ value	9.26847e-13 (rank : 114)	NC score	0.867381 (rank : 77)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	277
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB11_MOUSE
θ value	9.26847e-13 (rank : 115)	NC score	0.862151 (rank : 84)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

AN30A_HUMAN
θ value	1.2105e-12 (rank : 116)	NC score	0.628790 (rank : 197)
Query Neighborhood Hits	455	Target Neighborhood Hits	1119	Shared Neighborhood Hits	298
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANKS3_HUMAN
θ value	1.58096e-12 (rank : 117)	NC score	0.877796 (rank : 62)
Query Neighborhood Hits	455	Target Neighborhood Hits	355	Shared Neighborhood Hits	281
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR19_HUMAN
θ value	1.58096e-12 (rank : 118)	NC score	0.833317 (rank : 124)
Query Neighborhood Hits	455	Target Neighborhood Hits	276	Shared Neighborhood Hits	270
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ASB4_MOUSE
θ value	1.58096e-12 (rank : 119)	NC score	0.856799 (rank : 91)
Query Neighborhood Hits	455	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB5_MOUSE
θ value	1.58096e-12 (rank : 120)	NC score	0.856433 (rank : 92)
Query Neighborhood Hits	455	Target Neighborhood Hits	266	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

NFKB1_HUMAN
θ value	1.58096e-12 (rank : 121)	NC score	0.762687 (rank : 156)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANR39_MOUSE
θ value	2.0648e-12 (rank : 122)	NC score	0.892263 (rank : 45)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

POTE8_HUMAN
θ value	2.0648e-12 (rank : 123)	NC score	0.834274 (rank : 123)
Query Neighborhood Hits	455	Target Neighborhood Hits	337	Shared Neighborhood Hits	282
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ASB9_MOUSE
θ value	4.59992e-12 (rank : 124)	NC score	0.852924 (rank : 96)
Query Neighborhood Hits	455	Target Neighborhood Hits	257	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MPP8_HUMAN
θ value	4.59992e-12 (rank : 125)	NC score	0.717121 (rank : 179)
Query Neighborhood Hits	455	Target Neighborhood Hits	948	Shared Neighborhood Hits	280
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

PP16B_HUMAN
θ value	4.59992e-12 (rank : 126)	NC score	0.851085 (rank : 99)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	281
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ANR39_HUMAN
θ value	6.00763e-12 (rank : 127)	NC score	0.894036 (rank : 43)
Query Neighborhood Hits	455	Target Neighborhood Hits	285	Shared Neighborhood Hits	278
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB12_MOUSE
θ value	6.00763e-12 (rank : 128)	NC score	0.848888 (rank : 109)
Query Neighborhood Hits	455	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

GABP2_HUMAN
θ value	6.00763e-12 (rank : 129)	NC score	0.881522 (rank : 54)
Query Neighborhood Hits	455	Target Neighborhood Hits	454	Shared Neighborhood Hits	288
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

NOTC4_MOUSE
θ value	6.00763e-12 (rank : 130)	NC score	0.485231 (rank : 242)
Query Neighborhood Hits	455	Target Neighborhood Hits	872	Shared Neighborhood Hits	286
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

OSBL1_HUMAN
θ value	6.00763e-12 (rank : 131)	NC score	0.697852 (rank : 185)
Query Neighborhood Hits	455	Target Neighborhood Hits	368	Shared Neighborhood Hits	280
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

GABP2_MOUSE
θ value	1.02475e-11 (rank : 132)	NC score	0.883599 (rank : 50)
Query Neighborhood Hits	455	Target Neighborhood Hits	429	Shared Neighborhood Hits	289
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

PP16A_MOUSE
θ value	1.02475e-11 (rank : 133)	NC score	0.858583 (rank : 89)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	285
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

PP16B_MOUSE
θ value	1.02475e-11 (rank : 134)	NC score	0.849026 (rank : 108)
Query Neighborhood Hits	455	Target Neighborhood Hits	302	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

CDN2C_HUMAN
θ value	1.33837e-11 (rank : 135)	NC score	0.875002 (rank : 67)
Query Neighborhood Hits	455	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2C_MOUSE
θ value	1.33837e-11 (rank : 136)	NC score	0.874230 (rank : 68)
Query Neighborhood Hits	455	Target Neighborhood Hits	270	Shared Neighborhood Hits	267
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

NOTC4_HUMAN
θ value	1.33837e-11 (rank : 137)	NC score	0.477985 (rank : 244)
Query Neighborhood Hits	455	Target Neighborhood Hits	905	Shared Neighborhood Hits	290
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANR26_MOUSE
θ value	1.74796e-11 (rank : 138)	NC score	0.494441 (rank : 239)
Query Neighborhood Hits	455	Target Neighborhood Hits	1554	Shared Neighborhood Hits	306
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MYPT2_HUMAN
θ value	1.74796e-11 (rank : 139)	NC score	0.841484 (rank : 116)
Query Neighborhood Hits	455	Target Neighborhood Hits	707	Shared Neighborhood Hits	300
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

AN36B_HUMAN
θ value	2.28291e-11 (rank : 140)	NC score	0.859546 (rank : 87)
Query Neighborhood Hits	455	Target Neighborhood Hits	294	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR11_HUMAN
θ value	2.28291e-11 (rank : 141)	NC score	0.772109 (rank : 153)
Query Neighborhood Hits	455	Target Neighborhood Hits	1289	Shared Neighborhood Hits	327
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

OSBL1_MOUSE
θ value	2.28291e-11 (rank : 142)	NC score	0.686353 (rank : 186)
Query Neighborhood Hits	455	Target Neighborhood Hits	336	Shared Neighborhood Hits	278
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

BARD1_HUMAN
θ value	2.98157e-11 (rank : 143)	NC score	0.827237 (rank : 129)
Query Neighborhood Hits	455	Target Neighborhood Hits	427	Shared Neighborhood Hits	285
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR12_HUMAN
θ value	6.64225e-11 (rank : 144)	NC score	0.743184 (rank : 165)
Query Neighborhood Hits	455	Target Neighborhood Hits	1081	Shared Neighborhood Hits	311
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

NFKB2_HUMAN
θ value	6.64225e-11 (rank : 145)	NC score	0.757917 (rank : 162)
Query Neighborhood Hits	455	Target Neighborhood Hits	325	Shared Neighborhood Hits	280
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NFKB2_MOUSE
θ value	6.64225e-11 (rank : 146)	NC score	0.741633 (rank : 167)
Query Neighborhood Hits	455	Target Neighborhood Hits	326	Shared Neighborhood Hits	274
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

RFXK_MOUSE
θ value	6.64225e-11 (rank : 147)	NC score	0.855383 (rank : 94)
Query Neighborhood Hits	455	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB16_MOUSE
θ value	8.67504e-11 (rank : 148)	NC score	0.872889 (rank : 71)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

NFKB1_MOUSE
θ value	8.67504e-11 (rank : 149)	NC score	0.761407 (rank : 157)
Query Neighborhood Hits	455	Target Neighborhood Hits	300	Shared Neighborhood Hits	272
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

POT14_HUMAN
θ value	8.67504e-11 (rank : 150)	NC score	0.773689 (rank : 151)
Query Neighborhood Hits	455	Target Neighborhood Hits	403	Shared Neighborhood Hits	278
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

RFXK_HUMAN
θ value	8.67504e-11 (rank : 151)	NC score	0.862676 (rank : 83)
Query Neighborhood Hits	455	Target Neighborhood Hits	282	Shared Neighborhood Hits	266
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ASB4_HUMAN
θ value	1.133e-10 (rank : 152)	NC score	0.856259 (rank : 93)
Query Neighborhood Hits	455	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

BARD1_MOUSE
θ value	1.133e-10 (rank : 153)	NC score	0.826546 (rank : 131)
Query Neighborhood Hits	455	Target Neighborhood Hits	411	Shared Neighborhood Hits	281
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

SHAN1_HUMAN
θ value	1.47974e-10 (rank : 154)	NC score	0.742661 (rank : 166)
Query Neighborhood Hits	455	Target Neighborhood Hits	1041	Shared Neighborhood Hits	301
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR15_HUMAN
θ value	2.52405e-10 (rank : 155)	NC score	0.773372 (rank : 152)
Query Neighborhood Hits	455	Target Neighborhood Hits	478	Shared Neighborhood Hits	272
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ACBD6_MOUSE
θ value	5.62301e-10 (rank : 156)	NC score	0.833250 (rank : 125)
Query Neighborhood Hits	455	Target Neighborhood Hits	305	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ILK1_HUMAN
θ value	5.62301e-10 (rank : 157)	NC score	0.528178 (rank : 229)
Query Neighborhood Hits	455	Target Neighborhood Hits	857	Shared Neighborhood Hits	286
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	5.62301e-10 (rank : 158)	NC score	0.546597 (rank : 221)
Query Neighborhood Hits	455	Target Neighborhood Hits	848	Shared Neighborhood Hits	286
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

GABP3_MOUSE
θ value	7.34386e-10 (rank : 159)	NC score	0.878380 (rank : 60)
Query Neighborhood Hits	455	Target Neighborhood Hits	330	Shared Neighborhood Hits	280
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ASB1_HUMAN
θ value	9.59137e-10 (rank : 160)	NC score	0.842682 (rank : 114)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

PP16A_HUMAN
θ value	9.59137e-10 (rank : 161)	NC score	0.850248 (rank : 102)
Query Neighborhood Hits	455	Target Neighborhood Hits	340	Shared Neighborhood Hits	283
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ASB16_HUMAN
θ value	1.25267e-09 (rank : 162)	NC score	0.866467 (rank : 80)
Query Neighborhood Hits	455	Target Neighborhood Hits	286	Shared Neighborhood Hits	270
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ILK_MOUSE
θ value	1.25267e-09 (rank : 163)	NC score	0.526352 (rank : 231)
Query Neighborhood Hits	455	Target Neighborhood Hits	858	Shared Neighborhood Hits	284
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ANR10_MOUSE
θ value	1.63604e-09 (rank : 164)	NC score	0.844344 (rank : 112)
Query Neighborhood Hits	455	Target Neighborhood Hits	273	Shared Neighborhood Hits	262
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

AN36A_HUMAN
θ value	2.13673e-09 (rank : 165)	NC score	0.826645 (rank : 130)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	264
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ACBD6_HUMAN
θ value	3.64472e-09 (rank : 166)	NC score	0.827913 (rank : 127)
Query Neighborhood Hits	455	Target Neighborhood Hits	304	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR49_MOUSE
θ value	3.64472e-09 (rank : 167)	NC score	0.879145 (rank : 59)
Query Neighborhood Hits	455	Target Neighborhood Hits	285	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB1_MOUSE
θ value	3.64472e-09 (rank : 168)	NC score	0.840385 (rank : 118)
Query Neighborhood Hits	455	Target Neighborhood Hits	292	Shared Neighborhood Hits	272
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR49_HUMAN
θ value	6.21693e-09 (rank : 169)	NC score	0.875092 (rank : 66)
Query Neighborhood Hits	455	Target Neighborhood Hits	282	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

IKBE_MOUSE
θ value	6.21693e-09 (rank : 170)	NC score	0.841901 (rank : 115)
Query Neighborhood Hits	455	Target Neighborhood Hits	308	Shared Neighborhood Hits	274
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANS4B_HUMAN
θ value	8.11959e-09 (rank : 171)	NC score	0.799239 (rank : 138)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR25_HUMAN
θ value	1.06045e-08 (rank : 172)	NC score	0.729746 (rank : 172)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	268
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

OSTF1_HUMAN
θ value	1.38499e-08 (rank : 173)	NC score	0.667080 (rank : 191)
Query Neighborhood Hits	455	Target Neighborhood Hits	466	Shared Neighborhood Hits	257
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

IKBB_HUMAN
θ value	1.80886e-08 (rank : 174)	NC score	0.815746 (rank : 133)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ANKY2_HUMAN
θ value	2.36244e-08 (rank : 175)	NC score	0.785856 (rank : 146)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR10_HUMAN
θ value	3.08544e-08 (rank : 176)	NC score	0.844838 (rank : 111)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR25_MOUSE
θ value	3.08544e-08 (rank : 177)	NC score	0.715626 (rank : 181)
Query Neighborhood Hits	455	Target Neighborhood Hits	398	Shared Neighborhood Hits	271
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

OSTF1_MOUSE
θ value	4.0297e-08 (rank : 178)	NC score	0.682712 (rank : 188)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	260
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

POT22_HUMAN
θ value	4.0297e-08 (rank : 179)	NC score	0.729279 (rank : 173)
Query Neighborhood Hits	455	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ANKY2_MOUSE
θ value	6.87365e-08 (rank : 180)	NC score	0.760333 (rank : 159)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	256
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR47_HUMAN
θ value	6.87365e-08 (rank : 181)	NC score	0.749463 (rank : 163)
Query Neighborhood Hits	455	Target Neighborhood Hits	369	Shared Neighborhood Hits	265
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

CDN2D_HUMAN
θ value	6.87365e-08 (rank : 182)	NC score	0.858184 (rank : 90)
Query Neighborhood Hits	455	Target Neighborhood Hits	268	Shared Neighborhood Hits	266
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

KRIT1_MOUSE
θ value	6.87365e-08 (rank : 183)	NC score	0.719976 (rank : 176)
Query Neighborhood Hits	455	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

IKBA_HUMAN
θ value	8.97725e-08 (rank : 184)	NC score	0.848123 (rank : 110)
Query Neighborhood Hits	455	Target Neighborhood Hits	280	Shared Neighborhood Hits	272
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANR46_HUMAN
θ value	1.17247e-07 (rank : 185)	NC score	0.849639 (rank : 103)
Query Neighborhood Hits	455	Target Neighborhood Hits	281	Shared Neighborhood Hits	274
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

IKBB_MOUSE
θ value	1.17247e-07 (rank : 186)	NC score	0.812602 (rank : 134)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR46_MOUSE
θ value	1.53129e-07 (rank : 187)	NC score	0.844201 (rank : 113)
Query Neighborhood Hits	455	Target Neighborhood Hits	274	Shared Neighborhood Hits	268
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR47_MOUSE
θ value	1.53129e-07 (rank : 188)	NC score	0.767640 (rank : 154)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

TEX14_MOUSE
θ value	1.53129e-07 (rank : 189)	NC score	0.422782 (rank : 258)
Query Neighborhood Hits	455	Target Neighborhood Hits	1333	Shared Neighborhood Hits	283
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANR38_HUMAN
θ value	1.99992e-07 (rank : 190)	NC score	0.710324 (rank : 183)
Query Neighborhood Hits	455	Target Neighborhood Hits	443	Shared Neighborhood Hits	247
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CENB2_HUMAN
θ value	1.99992e-07 (rank : 191)	NC score	0.560313 (rank : 219)
Query Neighborhood Hits	455	Target Neighborhood Hits	425	Shared Neighborhood Hits	253
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

IKBA_MOUSE
θ value	1.99992e-07 (rank : 192)	NC score	0.836039 (rank : 122)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANR38_MOUSE
θ value	2.61198e-07 (rank : 193)	NC score	0.685996 (rank : 187)
Query Neighborhood Hits	455	Target Neighborhood Hits	512	Shared Neighborhood Hits	248
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

KRIT1_HUMAN
θ value	2.61198e-07 (rank : 194)	NC score	0.709863 (rank : 184)
Query Neighborhood Hits	455	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

USH1G_HUMAN
θ value	2.61198e-07 (rank : 195)	NC score	0.799572 (rank : 137)
Query Neighborhood Hits	455	Target Neighborhood Hits	267	Shared Neighborhood Hits	261
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	2.61198e-07 (rank : 196)	NC score	0.799638 (rank : 136)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

MTPN_MOUSE
θ value	3.41135e-07 (rank : 197)	NC score	0.868415 (rank : 76)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANR22_HUMAN
θ value	5.81887e-07 (rank : 198)	NC score	0.849583 (rank : 105)
Query Neighborhood Hits	455	Target Neighborhood Hits	243	Shared Neighborhood Hits	240
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

BCOR_HUMAN
θ value	5.81887e-07 (rank : 199)	NC score	0.729767 (rank : 171)
Query Neighborhood Hits	455	Target Neighborhood Hits	609	Shared Neighborhood Hits	298
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANS4B_MOUSE
θ value	7.59969e-07 (rank : 200)	NC score	0.786977 (rank : 143)
Query Neighborhood Hits	455	Target Neighborhood Hits	294	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

BCOR_MOUSE
θ value	7.59969e-07 (rank : 201)	NC score	0.736408 (rank : 168)
Query Neighborhood Hits	455	Target Neighborhood Hits	521	Shared Neighborhood Hits	287
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

MTPN_HUMAN
θ value	9.92553e-07 (rank : 202)	NC score	0.863760 (rank : 81)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANR33_MOUSE
θ value	1.69304e-06 (rank : 203)	NC score	0.745937 (rank : 164)
Query Neighborhood Hits	455	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ASB14_HUMAN
θ value	1.69304e-06 (rank : 204)	NC score	0.601214 (rank : 205)
Query Neighborhood Hits	455	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

IKBE_HUMAN
θ value	2.21117e-06 (rank : 205)	NC score	0.817171 (rank : 132)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	268
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANR41_HUMAN
θ value	3.77169e-06 (rank : 206)	NC score	0.784752 (rank : 148)
Query Neighborhood Hits	455	Target Neighborhood Hits	332	Shared Neighborhood Hits	256
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

SNCAP_HUMAN
θ value	3.77169e-06 (rank : 207)	NC score	0.757985 (rank : 161)
Query Neighborhood Hits	455	Target Neighborhood Hits	313	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

CDN2D_MOUSE
θ value	4.92598e-06 (rank : 208)	NC score	0.849589 (rank : 104)
Query Neighborhood Hits	455	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

TRPV6_MOUSE
θ value	4.92598e-06 (rank : 209)	NC score	0.581947 (rank : 212)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	252
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

CLPB_MOUSE
θ value	6.43352e-06 (rank : 210)	NC score	0.719553 (rank : 177)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	250
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR33_HUMAN
θ value	8.40245e-06 (rank : 211)	NC score	0.733596 (rank : 170)
Query Neighborhood Hits	455	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR45_MOUSE
θ value	8.40245e-06 (rank : 212)	NC score	0.650293 (rank : 193)
Query Neighborhood Hits	455	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

CENB1_HUMAN
θ value	1.09739e-05 (rank : 213)	NC score	0.566518 (rank : 218)
Query Neighborhood Hits	455	Target Neighborhood Hits	383	Shared Neighborhood Hits	258
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

TEX14_HUMAN
θ value	1.87187e-05 (rank : 214)	NC score	0.418983 (rank : 259)
Query Neighborhood Hits	455	Target Neighborhood Hits	1103	Shared Neighborhood Hits	267
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANR37_MOUSE
θ value	2.44474e-05 (rank : 215)	NC score	0.736084 (rank : 169)
Query Neighborhood Hits	455	Target Neighborhood Hits	237	Shared Neighborhood Hits	232
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

CENB5_HUMAN
θ value	2.44474e-05 (rank : 216)	NC score	0.568333 (rank : 216)
Query Neighborhood Hits	455	Target Neighborhood Hits	395	Shared Neighborhood Hits	263
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ABTB2_MOUSE
θ value	3.19293e-05 (rank : 217)	NC score	0.601142 (rank : 206)
Query Neighborhood Hits	455	Target Neighborhood Hits	414	Shared Neighborhood Hits	238
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR32_HUMAN
θ value	3.19293e-05 (rank : 218)	NC score	0.794331 (rank : 140)
Query Neighborhood Hits	455	Target Neighborhood Hits	270	Shared Neighborhood Hits	260
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR37_HUMAN
θ value	3.19293e-05 (rank : 219)	NC score	0.758922 (rank : 160)
Query Neighborhood Hits	455	Target Neighborhood Hits	247	Shared Neighborhood Hits	242
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ABTB2_HUMAN
θ value	4.1701e-05 (rank : 220)	NC score	0.611783 (rank : 202)
Query Neighborhood Hits	455	Target Neighborhood Hits	391	Shared Neighborhood Hits	238
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR32_MOUSE
θ value	4.1701e-05 (rank : 221)	NC score	0.783566 (rank : 149)
Query Neighborhood Hits	455	Target Neighborhood Hits	285	Shared Neighborhood Hits	260
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

HECD1_HUMAN
θ value	9.29e-05 (rank : 222)	NC score	0.621722 (rank : 201)
Query Neighborhood Hits	455	Target Neighborhood Hits	371	Shared Neighborhood Hits	271
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

FILA_HUMAN
θ value	0.000121331 (rank : 223)	NC score	0.061683 (rank : 319)
Query Neighborhood Hits	455	Target Neighborhood Hits	685	Shared Neighborhood Hits	57
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GLSK_HUMAN
θ value	0.000121331 (rank : 224)	NC score	0.507527 (rank : 236)
Query Neighborhood Hits	455	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

CENG3_HUMAN
θ value	0.000158464 (rank : 225)	NC score	0.340566 (rank : 277)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.000158464 (rank : 226)	NC score	0.340870 (rank : 276)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	229
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ABTB1_MOUSE
θ value	0.00020696 (rank : 227)	NC score	0.341525 (rank : 275)
Query Neighborhood Hits	455	Target Neighborhood Hits	349	Shared Neighborhood Hits	176
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

CLPB_HUMAN
θ value	0.000270298 (rank : 228)	NC score	0.625558 (rank : 199)
Query Neighborhood Hits	455	Target Neighborhood Hits	265	Shared Neighborhood Hits	235
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CMTA2_HUMAN
θ value	0.000270298 (rank : 229)	NC score	0.214935 (rank : 295)
Query Neighborhood Hits	455	Target Neighborhood Hits	199	Shared Neighborhood Hits	98
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ANR45_HUMAN
θ value	0.00035302 (rank : 230)	NC score	0.607657 (rank : 203)
Query Neighborhood Hits	455	Target Neighborhood Hits	201	Shared Neighborhood Hits	186
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

CMTA2_MOUSE
θ value	0.00035302 (rank : 231)	NC score	0.203696 (rank : 296)
Query Neighborhood Hits	455	Target Neighborhood Hits	216	Shared Neighborhood Hits	85
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

IASPP_HUMAN
θ value	0.00035302 (rank : 232)	NC score	0.569313 (rank : 215)
Query Neighborhood Hits	455	Target Neighborhood Hits	688	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ABTB1_HUMAN
θ value	0.000461057 (rank : 233)	NC score	0.298851 (rank : 282)
Query Neighborhood Hits	455	Target Neighborhood Hits	325	Shared Neighborhood Hits	161
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ASPP2_HUMAN
θ value	0.000461057 (rank : 234)	NC score	0.572800 (rank : 214)
Query Neighborhood Hits	455	Target Neighborhood Hits	1156	Shared Neighborhood Hits	307
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

GLSL_HUMAN
θ value	0.000602161 (rank : 235)	NC score	0.546048 (rank : 222)
Query Neighborhood Hits	455	Target Neighborhood Hits	211	Shared Neighborhood Hits	204
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

CMTA1_HUMAN
θ value	0.000786445 (rank : 236)	NC score	0.253876 (rank : 289)
Query Neighborhood Hits	455	Target Neighborhood Hits	217	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

SRRM2_HUMAN
θ value	0.000786445 (rank : 237)	NC score	0.085014 (rank : 305)
Query Neighborhood Hits	455	Target Neighborhood Hits	1296	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

IASPP_MOUSE
θ value	0.00102713 (rank : 238)	NC score	0.519791 (rank : 234)
Query Neighborhood Hits	455	Target Neighborhood Hits	1024	Shared Neighborhood Hits	302
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CD2L5_HUMAN
θ value	0.00134147 (rank : 239)	NC score	0.016514 (rank : 413)
Query Neighborhood Hits	455	Target Neighborhood Hits	987	Shared Neighborhood Hits	39
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

HORN_MOUSE
θ value	0.00134147 (rank : 240)	NC score	0.047051 (rank : 341)
Query Neighborhood Hits	455	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

SRRM2_MOUSE
θ value	0.00134147 (rank : 241)	NC score	0.072325 (rank : 309)
Query Neighborhood Hits	455	Target Neighborhood Hits	1470	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

XPC_MOUSE
θ value	0.00175202 (rank : 242)	NC score	0.042845 (rank : 346)
Query Neighborhood Hits	455	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

AN13C_HUMAN
θ value	0.00228821 (rank : 243)	NC score	0.538025 (rank : 225)
Query Neighborhood Hits	455	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_MOUSE
θ value	0.00228821 (rank : 244)	NC score	0.527191 (rank : 230)
Query Neighborhood Hits	455	Target Neighborhood Hits	242	Shared Neighborhood Hits	230
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

CENG2_MOUSE
θ value	0.00228821 (rank : 245)	NC score	0.367647 (rank : 271)
Query Neighborhood Hits	455	Target Neighborhood Hits	463	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

GLSL_MOUSE
θ value	0.00228821 (rank : 246)	NC score	0.533176 (rank : 228)
Query Neighborhood Hits	455	Target Neighborhood Hits	212	Shared Neighborhood Hits	205
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TRPV6_HUMAN
θ value	0.00228821 (rank : 247)	NC score	0.493300 (rank : 240)
Query Neighborhood Hits	455	Target Neighborhood Hits	262	Shared Neighborhood Hits	224
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

DGKZ_HUMAN
θ value	0.00298849 (rank : 248)	NC score	0.391492 (rank : 264)
Query Neighborhood Hits	455	Target Neighborhood Hits	551	Shared Neighborhood Hits	220
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

LRRK1_MOUSE
θ value	0.00298849 (rank : 249)	NC score	0.100929 (rank : 303)
Query Neighborhood Hits	455	Target Neighborhood Hits	1267	Shared Neighborhood Hits	135
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

ASB6_HUMAN
θ value	0.00390308 (rank : 250)	NC score	0.764403 (rank : 155)
Query Neighborhood Hits	455	Target Neighborhood Hits	256	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

MYLK2_HUMAN
θ value	0.00390308 (rank : 251)	NC score	0.020584 (rank : 387)
Query Neighborhood Hits	455	Target Neighborhood Hits	920	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

CT086_HUMAN
θ value	0.00509761 (rank : 252)	NC score	0.836932 (rank : 120)
Query Neighborhood Hits	455	Target Neighborhood Hits	277	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

GIT2_MOUSE
θ value	0.00509761 (rank : 253)	NC score	0.519844 (rank : 233)
Query Neighborhood Hits	455	Target Neighborhood Hits	323	Shared Neighborhood Hits	252
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

NUD12_HUMAN
θ value	0.00509761 (rank : 254)	NC score	0.566952 (rank : 217)
Query Neighborhood Hits	455	Target Neighborhood Hits	222	Shared Neighborhood Hits	203
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

NUD12_MOUSE
θ value	0.00509761 (rank : 255)	NC score	0.595933 (rank : 207)
Query Neighborhood Hits	455	Target Neighborhood Hits	243	Shared Neighborhood Hits	222
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

AN13A_HUMAN
θ value	0.00665767 (rank : 256)	NC score	0.475687 (rank : 246)
Query Neighborhood Hits	455	Target Neighborhood Hits	243	Shared Neighborhood Hits	221
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ASB6_MOUSE
θ value	0.00665767 (rank : 257)	NC score	0.760510 (rank : 158)
Query Neighborhood Hits	455	Target Neighborhood Hits	264	Shared Neighborhood Hits	244
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

BAT2_MOUSE
θ value	0.00665767 (rank : 258)	NC score	0.057873 (rank : 323)
Query Neighborhood Hits	455	Target Neighborhood Hits	947	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DGKZ_MOUSE
θ value	0.00665767 (rank : 259)	NC score	0.371719 (rank : 267)
Query Neighborhood Hits	455	Target Neighborhood Hits	542	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

TRPV1_MOUSE
θ value	0.00665767 (rank : 260)	NC score	0.262401 (rank : 285)
Query Neighborhood Hits	455	Target Neighborhood Hits	189	Shared Neighborhood Hits	153
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV5_MOUSE
θ value	0.00665767 (rank : 261)	NC score	0.521420 (rank : 232)
Query Neighborhood Hits	455	Target Neighborhood Hits	278	Shared Neighborhood Hits	245
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ACINU_MOUSE
θ value	0.00869519 (rank : 262)	NC score	0.048841 (rank : 338)
Query Neighborhood Hits	455	Target Neighborhood Hits	712	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ANKY1_HUMAN
θ value	0.00869519 (rank : 263)	NC score	0.592254 (rank : 209)
Query Neighborhood Hits	455	Target Neighborhood Hits	248	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANKZ1_MOUSE
θ value	0.00869519 (rank : 264)	NC score	0.363336 (rank : 272)
Query Neighborhood Hits	455	Target Neighborhood Hits	208	Shared Neighborhood Hits	152
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ASPP1_HUMAN
θ value	0.00869519 (rank : 265)	NC score	0.551264 (rank : 220)
Query Neighborhood Hits	455	Target Neighborhood Hits	956	Shared Neighborhood Hits	283
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	0.00869519 (rank : 266)	NC score	0.536642 (rank : 227)
Query Neighborhood Hits	455	Target Neighborhood Hits	1244	Shared Neighborhood Hits	303
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CENG2_HUMAN
θ value	0.00869519 (rank : 267)	NC score	0.369154 (rank : 270)
Query Neighborhood Hits	455	Target Neighborhood Hits	471	Shared Neighborhood Hits	252
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

SFRS4_HUMAN
θ value	0.00869519 (rank : 268)	NC score	0.043637 (rank : 344)
Query Neighborhood Hits	455	Target Neighborhood Hits	384	Shared Neighborhood Hits	30
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

ANR43_HUMAN
θ value	0.0113563 (rank : 269)	NC score	0.630297 (rank : 196)
Query Neighborhood Hits	455	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_MOUSE
θ value	0.0113563 (rank : 270)	NC score	0.622068 (rank : 200)
Query Neighborhood Hits	455	Target Neighborhood Hits	214	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CD2A1_MOUSE
θ value	0.0113563 (rank : 271)	NC score	0.714394 (rank : 182)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	204
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

DDEF2_HUMAN
θ value	0.0113563 (rank : 272)	NC score	0.400488 (rank : 262)
Query Neighborhood Hits	455	Target Neighborhood Hits	599	Shared Neighborhood Hits	247
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.0113563 (rank : 273)	NC score	0.397817 (rank : 263)
Query Neighborhood Hits	455	Target Neighborhood Hits	625	Shared Neighborhood Hits	249
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_MOUSE
θ value	0.0113563 (rank : 274)	NC score	0.474749 (rank : 247)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	249
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

ANKZ1_HUMAN
θ value	0.0148317 (rank : 275)	NC score	0.346747 (rank : 274)
Query Neighborhood Hits	455	Target Neighborhood Hits	236	Shared Neighborhood Hits	157
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

CDN2B_MOUSE
θ value	0.0148317 (rank : 276)	NC score	0.675418 (rank : 190)
Query Neighborhood Hits	455	Target Neighborhood Hits	201	Shared Neighborhood Hits	198
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

AN13B_HUMAN
θ value	0.0193708 (rank : 277)	NC score	0.537987 (rank : 226)
Query Neighborhood Hits	455	Target Neighborhood Hits	265	Shared Neighborhood Hits	251
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	0.0193708 (rank : 278)	NC score	0.538592 (rank : 224)
Query Neighborhood Hits	455	Target Neighborhood Hits	276	Shared Neighborhood Hits	254
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CMGA_HUMAN
θ value	0.0193708 (rank : 279)	NC score	0.047087 (rank : 340)
Query Neighborhood Hits	455	Target Neighborhood Hits	238	Shared Neighborhood Hits	21
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

PRP1_HUMAN
θ value	0.0193708 (rank : 280)	NC score	0.063069 (rank : 316)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	48
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SFRS4_MOUSE
θ value	0.0193708 (rank : 281)	NC score	0.032055 (rank : 365)
Query Neighborhood Hits	455	Target Neighborhood Hits	406	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TRPV1_HUMAN
θ value	0.0193708 (rank : 282)	NC score	0.245269 (rank : 290)
Query Neighborhood Hits	455	Target Neighborhood Hits	184	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

CD2L5_MOUSE
θ value	0.0252991 (rank : 283)	NC score	0.015714 (rank : 415)
Query Neighborhood Hits	455	Target Neighborhood Hits	1011	Shared Neighborhood Hits	45
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

DDFL1_HUMAN
θ value	0.0252991 (rank : 284)	NC score	0.381161 (rank : 265)
Query Neighborhood Hits	455	Target Neighborhood Hits	353	Shared Neighborhood Hits	235
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FOG2_HUMAN
θ value	0.0252991 (rank : 285)	NC score	0.002364 (rank : 474)
Query Neighborhood Hits	455	Target Neighborhood Hits	731	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

RSNL2_HUMAN
θ value	0.0252991 (rank : 286)	NC score	0.260572 (rank : 286)
Query Neighborhood Hits	455	Target Neighborhood Hits	136	Shared Neighborhood Hits	114
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	0.0252991 (rank : 287)	NC score	0.224636 (rank : 293)
Query Neighborhood Hits	455	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

GIT2_HUMAN
θ value	0.0330416 (rank : 288)	NC score	0.479328 (rank : 243)
Query Neighborhood Hits	455	Target Neighborhood Hits	381	Shared Neighborhood Hits	245
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

MUC1_MOUSE
θ value	0.0330416 (rank : 289)	NC score	0.040591 (rank : 351)
Query Neighborhood Hits	455	Target Neighborhood Hits	388	Shared Neighborhood Hits	35
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

TRPV3_MOUSE
θ value	0.0330416 (rank : 290)	NC score	0.260189 (rank : 287)
Query Neighborhood Hits	455	Target Neighborhood Hits	188	Shared Neighborhood Hits	129
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

CJ047_HUMAN
θ value	0.0431538 (rank : 291)	NC score	0.035630 (rank : 358)
Query Neighborhood Hits	455	Target Neighborhood Hits	164	Shared Neighborhood Hits	23
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

DGKI_HUMAN
θ value	0.0431538 (rank : 292)	NC score	0.358996 (rank : 273)
Query Neighborhood Hits	455	Target Neighborhood Hits	609	Shared Neighborhood Hits	222
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

CDN2B_HUMAN
θ value	0.0563607 (rank : 293)	NC score	0.627279 (rank : 198)
Query Neighborhood Hits	455	Target Neighborhood Hits	196	Shared Neighborhood Hits	195
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CENG1_HUMAN
θ value	0.0563607 (rank : 294)	NC score	0.369222 (rank : 269)
Query Neighborhood Hits	455	Target Neighborhood Hits	544	Shared Neighborhood Hits	246
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	0.0563607 (rank : 295)	NC score	0.371322 (rank : 268)
Query Neighborhood Hits	455	Target Neighborhood Hits	531	Shared Neighborhood Hits	245
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CLIC6_HUMAN
θ value	0.0961366 (rank : 296)	NC score	0.017551 (rank : 408)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	30
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

PRP4B_MOUSE
θ value	0.0961366 (rank : 297)	NC score	0.018541 (rank : 403)
Query Neighborhood Hits	455	Target Neighborhood Hits	1040	Shared Neighborhood Hits	49
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

TRPV5_HUMAN
θ value	0.0961366 (rank : 298)	NC score	0.491142 (rank : 241)
Query Neighborhood Hits	455	Target Neighborhood Hits	261	Shared Neighborhood Hits	223
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

GIT1_HUMAN
θ value	0.125558 (rank : 299)	NC score	0.498096 (rank : 238)
Query Neighborhood Hits	455	Target Neighborhood Hits	336	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.125558 (rank : 300)	NC score	0.499435 (rank : 237)
Query Neighborhood Hits	455	Target Neighborhood Hits	341	Shared Neighborhood Hits	247
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

P_HUMAN
θ value	0.125558 (rank : 301)	NC score	0.020256 (rank : 390)
Query Neighborhood Hits	455	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q04671, Q15211, Q15212, Q96EN1, Q9UMI5	Gene names	OCA2, P
Domain Architecture
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog).

SPEG_HUMAN
θ value	0.125558 (rank : 302)	NC score	0.014957 (rank : 419)
Query Neighborhood Hits	455	Target Neighborhood Hits	1762	Shared Neighborhood Hits	89
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYN3_MOUSE
θ value	0.125558 (rank : 303)	NC score	0.026936 (rank : 374)
Query Neighborhood Hits	455	Target Neighborhood Hits	200	Shared Neighborhood Hits	33
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

AN13A_MOUSE
θ value	0.163984 (rank : 304)	NC score	0.448929 (rank : 251)
Query Neighborhood Hits	455	Target Neighborhood Hits	226	Shared Neighborhood Hits	215
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

DDEF1_MOUSE
θ value	0.163984 (rank : 305)	NC score	0.301940 (rank : 281)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	205
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

RRBP1_MOUSE
θ value	0.163984 (rank : 306)	NC score	0.041519 (rank : 349)
Query Neighborhood Hits	455	Target Neighborhood Hits	1650	Shared Neighborhood Hits	100
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TRPV3_HUMAN
θ value	0.163984 (rank : 307)	NC score	0.256336 (rank : 288)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	142
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

ASPM_MOUSE
θ value	0.21417 (rank : 308)	NC score	0.026323 (rank : 375)
Query Neighborhood Hits	455	Target Neighborhood Hits	150	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

BAT2_HUMAN
θ value	0.21417 (rank : 309)	NC score	0.058748 (rank : 322)
Query Neighborhood Hits	455	Target Neighborhood Hits	931	Shared Neighborhood Hits	91
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DSPP_HUMAN
θ value	0.21417 (rank : 310)	NC score	0.027504 (rank : 372)
Query Neighborhood Hits	455	Target Neighborhood Hits	645	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FYB_HUMAN
θ value	0.21417 (rank : 311)	NC score	0.036879 (rank : 357)
Query Neighborhood Hits	455	Target Neighborhood Hits	379	Shared Neighborhood Hits	51
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

RECQ5_HUMAN
θ value	0.21417 (rank : 312)	NC score	0.017810 (rank : 407)
Query Neighborhood Hits	455	Target Neighborhood Hits	390	Shared Neighborhood Hits	46
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

REPS1_HUMAN
θ value	0.21417 (rank : 313)	NC score	0.022462 (rank : 382)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	17
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RP3A_MOUSE
θ value	0.21417 (rank : 314)	NC score	0.009634 (rank : 444)
Query Neighborhood Hits	455	Target Neighborhood Hits	510	Shared Neighborhood Hits	54
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TRPC6_HUMAN
θ value	0.21417 (rank : 315)	NC score	0.112807 (rank : 302)
Query Neighborhood Hits	455	Target Neighborhood Hits	171	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

OBSCN_HUMAN
θ value	0.279714 (rank : 316)	NC score	0.013132 (rank : 430)
Query Neighborhood Hits	455	Target Neighborhood Hits	1931	Shared Neighborhood Hits	91
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PRB3_HUMAN
θ value	0.279714 (rank : 317)	NC score	0.041842 (rank : 348)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	42
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

SRCA_HUMAN
θ value	0.279714 (rank : 318)	NC score	0.022049 (rank : 384)
Query Neighborhood Hits	455	Target Neighborhood Hits	380	Shared Neighborhood Hits	41
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

ZN445_HUMAN
θ value	0.279714 (rank : 319)	NC score	-0.011534 (rank : 484)
Query Neighborhood Hits	455	Target Neighborhood Hits	764	Shared Neighborhood Hits	18
SwissProt Accessions	P59923	Gene names	ZNF445, ZNF168
Domain Architecture
Description	Zinc finger protein 445.

DOS_HUMAN
θ value	0.365318 (rank : 320)	NC score	0.027069 (rank : 373)
Query Neighborhood Hits	455	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

REPS1_MOUSE
θ value	0.365318 (rank : 321)	NC score	0.031829 (rank : 367)
Query Neighborhood Hits	455	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SRRM1_HUMAN
θ value	0.365318 (rank : 322)	NC score	0.060908 (rank : 320)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CASZ1_HUMAN
θ value	0.47712 (rank : 323)	NC score	0.007843 (rank : 451)
Query Neighborhood Hits	455	Target Neighborhood Hits	473	Shared Neighborhood Hits	15
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

CD2A1_HUMAN
θ value	0.47712 (rank : 324)	NC score	0.633335 (rank : 195)
Query Neighborhood Hits	455	Target Neighborhood Hits	196	Shared Neighborhood Hits	192
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

PKHA4_HUMAN
θ value	0.47712 (rank : 325)	NC score	0.028534 (rank : 370)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CO5A1_HUMAN
θ value	0.62314 (rank : 326)	NC score	0.012346 (rank : 431)
Query Neighborhood Hits	455	Target Neighborhood Hits	434	Shared Neighborhood Hits	41
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

MARK2_HUMAN
θ value	0.62314 (rank : 327)	NC score	0.019094 (rank : 401)
Query Neighborhood Hits	455	Target Neighborhood Hits	1056	Shared Neighborhood Hits	58
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MUCDL_MOUSE
θ value	0.62314 (rank : 328)	NC score	0.016618 (rank : 412)
Query Neighborhood Hits	455	Target Neighborhood Hits	461	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PP1RA_MOUSE
θ value	0.62314 (rank : 329)	NC score	0.020590 (rank : 386)
Query Neighborhood Hits	455	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

SRRM1_MOUSE
θ value	0.62314 (rank : 330)	NC score	0.070337 (rank : 312)
Query Neighborhood Hits	455	Target Neighborhood Hits	966	Shared Neighborhood Hits	91
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

YBOX2_MOUSE
θ value	0.62314 (rank : 331)	NC score	0.014708 (rank : 420)
Query Neighborhood Hits	455	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

ZN509_MOUSE
θ value	0.62314 (rank : 332)	NC score	-0.011654 (rank : 485)
Query Neighborhood Hits	455	Target Neighborhood Hits	990	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ANR40_HUMAN
θ value	1.06291 (rank : 333)	NC score	0.582936 (rank : 211)
Query Neighborhood Hits	455	Target Neighborhood Hits	224	Shared Neighborhood Hits	200
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

LRRK1_HUMAN
θ value	1.06291 (rank : 334)	NC score	0.073385 (rank : 308)
Query Neighborhood Hits	455	Target Neighborhood Hits	1237	Shared Neighborhood Hits	108
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

NFH_MOUSE
θ value	1.06291 (rank : 335)	NC score	0.046393 (rank : 342)
Query Neighborhood Hits	455	Target Neighborhood Hits	2247	Shared Neighborhood Hits	152
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RBM15_HUMAN
θ value	1.06291 (rank : 336)	NC score	0.019681 (rank : 396)
Query Neighborhood Hits	455	Target Neighborhood Hits	309	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

ROBO1_HUMAN
θ value	1.06291 (rank : 337)	NC score	-0.004142 (rank : 479)
Query Neighborhood Hits	455	Target Neighborhood Hits	529	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

SFPQ_MOUSE
θ value	1.06291 (rank : 338)	NC score	0.022191 (rank : 383)
Query Neighborhood Hits	455	Target Neighborhood Hits	958	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CCNK_MOUSE
θ value	1.38821 (rank : 339)	NC score	0.019105 (rank : 400)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	29
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CO1A1_HUMAN
θ value	1.38821 (rank : 340)	NC score	0.013647 (rank : 425)
Query Neighborhood Hits	455	Target Neighborhood Hits	475	Shared Neighborhood Hits	43
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO9A2_MOUSE
θ value	1.38821 (rank : 341)	NC score	0.004697 (rank : 463)
Query Neighborhood Hits	455	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

DNM3A_MOUSE
θ value	1.38821 (rank : 342)	NC score	0.011242 (rank : 436)
Query Neighborhood Hits	455	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

HTF4_HUMAN
θ value	1.38821 (rank : 343)	NC score	0.017336 (rank : 409)
Query Neighborhood Hits	455	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

HTF4_MOUSE
θ value	1.38821 (rank : 344)	NC score	0.015568 (rank : 416)
Query Neighborhood Hits	455	Target Neighborhood Hits	153	Shared Neighborhood Hits	12
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

NFH_HUMAN
θ value	1.38821 (rank : 345)	NC score	0.030223 (rank : 368)
Query Neighborhood Hits	455	Target Neighborhood Hits	1242	Shared Neighborhood Hits	84
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NKTR_MOUSE
θ value	1.38821 (rank : 346)	NC score	0.015325 (rank : 418)
Query Neighborhood Hits	455	Target Neighborhood Hits	417	Shared Neighborhood Hits	35
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

POL2_MOUSE
θ value	1.38821 (rank : 347)	NC score	0.010560 (rank : 439)
Query Neighborhood Hits	455	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P11369, Q60713, Q61787	Gene names	Pol
Domain Architecture
Description	Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element- 1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease].

RIMB1_MOUSE
θ value	1.38821 (rank : 348)	NC score	0.025344 (rank : 376)
Query Neighborhood Hits	455	Target Neighborhood Hits	1376	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TRPC3_HUMAN
θ value	1.38821 (rank : 349)	NC score	0.089068 (rank : 304)
Query Neighborhood Hits	455	Target Neighborhood Hits	137	Shared Neighborhood Hits	79
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
θ value	1.38821 (rank : 350)	NC score	0.082180 (rank : 306)
Query Neighborhood Hits	455	Target Neighborhood Hits	171	Shared Neighborhood Hits	87
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPV2_HUMAN
θ value	1.38821 (rank : 351)	NC score	0.224430 (rank : 294)
Query Neighborhood Hits	455	Target Neighborhood Hits	130	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CABYR_MOUSE
θ value	1.81305 (rank : 352)	NC score	0.019620 (rank : 397)
Query Neighborhood Hits	455	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CD5R2_MOUSE
θ value	1.81305 (rank : 353)	NC score	0.010708 (rank : 438)
Query Neighborhood Hits	455	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

DBNL_MOUSE
θ value	1.81305 (rank : 354)	NC score	0.014124 (rank : 423)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	21
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

ENL_HUMAN
θ value	1.81305 (rank : 355)	NC score	0.035437 (rank : 359)
Query Neighborhood Hits	455	Target Neighborhood Hits	305	Shared Neighborhood Hits	37
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

FOG1_MOUSE
θ value	1.81305 (rank : 356)	NC score	0.002735 (rank : 473)
Query Neighborhood Hits	455	Target Neighborhood Hits	1237	Shared Neighborhood Hits	73
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

K1683_HUMAN
θ value	1.81305 (rank : 357)	NC score	0.029530 (rank : 369)
Query Neighborhood Hits	455	Target Neighborhood Hits	240	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

K1914_HUMAN
θ value	1.81305 (rank : 358)	NC score	0.018505 (rank : 404)
Query Neighborhood Hits	455	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

KCNQ2_HUMAN
θ value	1.81305 (rank : 359)	NC score	0.007881 (rank : 450)
Query Neighborhood Hits	455	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

NCOR2_HUMAN
θ value	1.81305 (rank : 360)	NC score	0.032049 (rank : 366)
Query Neighborhood Hits	455	Target Neighborhood Hits	870	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

RNF25_HUMAN
θ value	1.81305 (rank : 361)	NC score	0.017937 (rank : 406)
Query Neighborhood Hits	455	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

SYN3_HUMAN
θ value	1.81305 (rank : 362)	NC score	0.020417 (rank : 389)
Query Neighborhood Hits	455	Target Neighborhood Hits	203	Shared Neighborhood Hits	31
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TIF1G_MOUSE
θ value	1.81305 (rank : 363)	NC score	0.004179 (rank : 467)
Query Neighborhood Hits	455	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ASPX_HUMAN
θ value	2.36792 (rank : 364)	NC score	0.019578 (rank : 399)
Query Neighborhood Hits	455	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

GLI1_MOUSE
θ value	2.36792 (rank : 365)	NC score	-0.010854 (rank : 483)
Query Neighborhood Hits	455	Target Neighborhood Hits	785	Shared Neighborhood Hits	22
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

ITF2_HUMAN
θ value	2.36792 (rank : 366)	NC score	0.019905 (rank : 394)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	17
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

MYO3A_HUMAN
θ value	2.36792 (rank : 367)	NC score	0.009750 (rank : 442)
Query Neighborhood Hits	455	Target Neighborhood Hits	1033	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

PRB4S_HUMAN
θ value	2.36792 (rank : 368)	NC score	0.045565 (rank : 343)
Query Neighborhood Hits	455	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

RBMX2_HUMAN
θ value	2.36792 (rank : 369)	NC score	0.005700 (rank : 458)
Query Neighborhood Hits	455	Target Neighborhood Hits	351	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y388, Q5JY82, Q9Y3I8	Gene names	RBMX2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

RGS3_HUMAN
θ value	2.36792 (rank : 370)	NC score	0.019830 (rank : 395)
Query Neighborhood Hits	455	Target Neighborhood Hits	1375	Shared Neighborhood Hits	92
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	2.36792 (rank : 371)	NC score	0.033493 (rank : 361)
Query Neighborhood Hits	455	Target Neighborhood Hits	1621	Shared Neighborhood Hits	118
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SFPQ_HUMAN
θ value	2.36792 (rank : 372)	NC score	0.020422 (rank : 388)
Query Neighborhood Hits	455	Target Neighborhood Hits	986	Shared Neighborhood Hits	63
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

STRAD_MOUSE
θ value	2.36792 (rank : 373)	NC score	0.028225 (rank : 371)
Query Neighborhood Hits	455	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	Q60924	Gene names	Stra13
Domain Architecture	No domain graphic available
Description	Retinoic acid-inducible E3 protein (Hematopoietic-specific protein E3).

TCAL5_HUMAN
θ value	2.36792 (rank : 374)	NC score	0.020722 (rank : 385)
Query Neighborhood Hits	455	Target Neighborhood Hits	806	Shared Neighborhood Hits	62
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ANR40_MOUSE
θ value	3.0926 (rank : 375)	NC score	0.577465 (rank : 213)
Query Neighborhood Hits	455	Target Neighborhood Hits	228	Shared Neighborhood Hits	202
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

BPTF_HUMAN
θ value	3.0926 (rank : 376)	NC score	0.017321 (rank : 411)
Query Neighborhood Hits	455	Target Neighborhood Hits	786	Shared Neighborhood Hits	49
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CAC1B_HUMAN
θ value	3.0926 (rank : 377)	NC score	0.003833 (rank : 469)
Query Neighborhood Hits	455	Target Neighborhood Hits	257	Shared Neighborhood Hits	23
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1H_HUMAN
θ value	3.0926 (rank : 378)	NC score	0.004565 (rank : 465)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	28
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CK035_HUMAN
θ value	3.0926 (rank : 379)	NC score	0.010130 (rank : 441)
Query Neighborhood Hits	455	Target Neighborhood Hits	149	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXW0	Gene names	C11orf35
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35.

CM003_HUMAN
θ value	3.0926 (rank : 380)	NC score	0.012061 (rank : 432)
Query Neighborhood Hits	455	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IX90, Q5VZV5, Q86WR2, Q8NBG1, Q96D22	Gene names	C13orf3, RAMA1
Domain Architecture	No domain graphic available
Description	Protein C13orf3.

ELOA3_HUMAN
θ value	3.0926 (rank : 381)	NC score	0.013801 (rank : 424)
Query Neighborhood Hits	455	Target Neighborhood Hits	98	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

GGN_HUMAN
θ value	3.0926 (rank : 382)	NC score	0.014231 (rank : 421)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	27
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

IRX5_MOUSE
θ value	3.0926 (rank : 383)	NC score	0.005684 (rank : 459)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

KCNQ5_HUMAN
θ value	3.0926 (rank : 384)	NC score	0.008753 (rank : 446)
Query Neighborhood Hits	455	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

PAK6_HUMAN
θ value	3.0926 (rank : 385)	NC score	0.011983 (rank : 433)
Query Neighborhood Hits	455	Target Neighborhood Hits	915	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

PP1RA_HUMAN
θ value	3.0926 (rank : 386)	NC score	0.015377 (rank : 417)
Query Neighborhood Hits	455	Target Neighborhood Hits	180	Shared Neighborhood Hits	22
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

PPRB_MOUSE
θ value	3.0926 (rank : 387)	NC score	0.024278 (rank : 377)
Query Neighborhood Hits	455	Target Neighborhood Hits	354	Shared Neighborhood Hits	37
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RNF12_HUMAN
θ value	3.0926 (rank : 388)	NC score	0.007133 (rank : 454)
Query Neighborhood Hits	455	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

TARA_HUMAN
θ value	3.0926 (rank : 389)	NC score	0.064104 (rank : 314)
Query Neighborhood Hits	455	Target Neighborhood Hits	1626	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TTBK1_HUMAN
θ value	3.0926 (rank : 390)	NC score	0.005819 (rank : 456)
Query Neighborhood Hits	455	Target Neighborhood Hits	1058	Shared Neighborhood Hits	51
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ZN447_HUMAN
θ value	3.0926 (rank : 391)	NC score	-0.005076 (rank : 480)
Query Neighborhood Hits	455	Target Neighborhood Hits	899	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

ACINU_HUMAN
θ value	4.03905 (rank : 392)	NC score	0.040933 (rank : 350)
Query Neighborhood Hits	455	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF4_HUMAN
θ value	4.03905 (rank : 393)	NC score	0.037395 (rank : 355)
Query Neighborhood Hits	455	Target Neighborhood Hits	611	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CUTL1_HUMAN
θ value	4.03905 (rank : 394)	NC score	0.024057 (rank : 378)
Query Neighborhood Hits	455	Target Neighborhood Hits	1574	Shared Neighborhood Hits	70
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DHDDS_MOUSE
θ value	4.03905 (rank : 395)	NC score	0.015826 (rank : 414)
Query Neighborhood Hits	455	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KU1, Q3UF13, Q8BZ16, Q8BZK8	Gene names	Dhdds
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).

ITF2_MOUSE
θ value	4.03905 (rank : 396)	NC score	0.019964 (rank : 393)
Query Neighborhood Hits	455	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

JPH2_MOUSE
θ value	4.03905 (rank : 397)	NC score	0.014207 (rank : 422)
Query Neighborhood Hits	455	Target Neighborhood Hits	279	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MARCO_HUMAN
θ value	4.03905 (rank : 398)	NC score	0.002990 (rank : 472)
Query Neighborhood Hits	455	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

MUCDL_HUMAN
θ value	4.03905 (rank : 399)	NC score	0.032996 (rank : 363)
Query Neighborhood Hits	455	Target Neighborhood Hits	777	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NACAM_MOUSE
θ value	4.03905 (rank : 400)	NC score	0.047720 (rank : 339)
Query Neighborhood Hits	455	Target Neighborhood Hits	1866	Shared Neighborhood Hits	130
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PCLO_HUMAN
θ value	4.03905 (rank : 401)	NC score	0.042154 (rank : 347)
Query Neighborhood Hits	455	Target Neighborhood Hits	2046	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PKHA5_HUMAN
θ value	4.03905 (rank : 402)	NC score	0.019073 (rank : 402)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RNF25_MOUSE
θ value	4.03905 (rank : 403)	NC score	0.011523 (rank : 434)
Query Neighborhood Hits	455	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

SPTN4_HUMAN
θ value	4.03905 (rank : 404)	NC score	0.002085 (rank : 475)
Query Neighborhood Hits	455	Target Neighborhood Hits	570	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

ST5_HUMAN
θ value	4.03905 (rank : 405)	NC score	0.005045 (rank : 461)
Query Neighborhood Hits	455	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

UT14B_MOUSE
θ value	4.03905 (rank : 406)	NC score	0.008494 (rank : 447)
Query Neighborhood Hits	455	Target Neighborhood Hits	226	Shared Neighborhood Hits	14
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

AATK_MOUSE
θ value	5.27518 (rank : 407)	NC score	0.013183 (rank : 429)
Query Neighborhood Hits	455	Target Neighborhood Hits	942	Shared Neighborhood Hits	48
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

AFF1_HUMAN
θ value	5.27518 (rank : 408)	NC score	0.037670 (rank : 354)
Query Neighborhood Hits	455	Target Neighborhood Hits	506	Shared Neighborhood Hits	62
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ANKF1_HUMAN
θ value	5.27518 (rank : 409)	NC score	0.142129 (rank : 298)
Query Neighborhood Hits	455	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CD2_HUMAN
θ value	5.27518 (rank : 410)	NC score	0.020070 (rank : 392)
Query Neighborhood Hits	455	Target Neighborhood Hits	504	Shared Neighborhood Hits	41
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CO039_HUMAN
θ value	5.27518 (rank : 411)	NC score	0.017323 (rank : 410)
Query Neighborhood Hits	455	Target Neighborhood Hits	264	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

FBX42_HUMAN
θ value	5.27518 (rank : 412)	NC score	0.005802 (rank : 457)
Query Neighborhood Hits	455	Target Neighborhood Hits	121	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

IF39_MOUSE
θ value	5.27518 (rank : 413)	NC score	0.011342 (rank : 435)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	18
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

IQGA1_MOUSE
θ value	5.27518 (rank : 414)	NC score	0.010299 (rank : 440)
Query Neighborhood Hits	455	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

MEF2D_HUMAN
θ value	5.27518 (rank : 415)	NC score	0.005265 (rank : 460)
Query Neighborhood Hits	455	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MMP10_HUMAN
θ value	5.27518 (rank : 416)	NC score	-0.001612 (rank : 478)
Query Neighborhood Hits	455	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

PCLO_MOUSE
θ value	5.27518 (rank : 417)	NC score	0.034805 (rank : 360)
Query Neighborhood Hits	455	Target Neighborhood Hits	2275	Shared Neighborhood Hits	133
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SFR11_HUMAN
θ value	5.27518 (rank : 418)	NC score	0.043634 (rank : 345)
Query Neighborhood Hits	455	Target Neighborhood Hits	246	Shared Neighborhood Hits	26
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SPTN5_HUMAN
θ value	5.27518 (rank : 419)	NC score	0.010980 (rank : 437)
Query Neighborhood Hits	455	Target Neighborhood Hits	674	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

ADRM1_HUMAN
θ value	6.88961 (rank : 420)	NC score	0.019606 (rank : 398)
Query Neighborhood Hits	455	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

AL2S4_HUMAN
θ value	6.88961 (rank : 421)	NC score	0.013327 (rank : 427)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q96Q45, Q53TS9, Q53TT2, Q7Z3B6, Q8IZ18, Q8NBF8, Q96CY1	Gene names	ALS2CR4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein.

APXL_HUMAN
θ value	6.88961 (rank : 422)	NC score	0.018002 (rank : 405)
Query Neighborhood Hits	455	Target Neighborhood Hits	553	Shared Neighborhood Hits	49
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CD2L6_MOUSE
θ value	6.88961 (rank : 423)	NC score	0.008085 (rank : 449)
Query Neighborhood Hits	455	Target Neighborhood Hits	851	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

DOT1L_HUMAN
θ value	6.88961 (rank : 424)	NC score	0.023466 (rank : 379)
Query Neighborhood Hits	455	Target Neighborhood Hits	660	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GON4L_MOUSE
θ value	6.88961 (rank : 425)	NC score	0.020192 (rank : 391)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HORN_HUMAN
θ value	6.88961 (rank : 426)	NC score	0.032114 (rank : 364)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

JHD2C_MOUSE
θ value	6.88961 (rank : 427)	NC score	0.009664 (rank : 443)
Query Neighborhood Hits	455	Target Neighborhood Hits	297	Shared Neighborhood Hits	30
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

KCNQ3_HUMAN
θ value	6.88961 (rank : 428)	NC score	0.004311 (rank : 466)
Query Neighborhood Hits	455	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	6.88961 (rank : 429)	NC score	0.004577 (rank : 464)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MAP1B_MOUSE
θ value	6.88961 (rank : 430)	NC score	0.038168 (rank : 353)
Query Neighborhood Hits	455	Target Neighborhood Hits	977	Shared Neighborhood Hits	71
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYO3A_MOUSE
θ value	6.88961 (rank : 431)	NC score	0.007213 (rank : 453)
Query Neighborhood Hits	455	Target Neighborhood Hits	902	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

NDST2_MOUSE
θ value	6.88961 (rank : 432)	NC score	0.000212 (rank : 476)
Query Neighborhood Hits	455	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NIN_MOUSE
θ value	6.88961 (rank : 433)	NC score	0.033122 (rank : 362)
Query Neighborhood Hits	455	Target Neighborhood Hits	1376	Shared Neighborhood Hits	50
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

RTEL1_HUMAN
θ value	6.88961 (rank : 434)	NC score	0.004768 (rank : 462)
Query Neighborhood Hits	455	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

SEPT7_HUMAN
θ value	6.88961 (rank : 435)	NC score	0.007608 (rank : 452)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

SET1A_HUMAN
θ value	6.88961 (rank : 436)	NC score	0.049460 (rank : 337)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	57
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SPAG4_MOUSE
θ value	6.88961 (rank : 437)	NC score	0.003262 (rank : 471)
Query Neighborhood Hits	455	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJF2	Gene names	Spag4
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 4 protein (Outer dense fiber-associated protein SPAG4).

ZAN_MOUSE
θ value	6.88961 (rank : 438)	NC score	0.037019 (rank : 356)
Query Neighborhood Hits	455	Target Neighborhood Hits	808	Shared Neighborhood Hits	20
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZEP2_HUMAN
θ value	6.88961 (rank : 439)	NC score	-0.008401 (rank : 481)
Query Neighborhood Hits	455	Target Neighborhood Hits	937	Shared Neighborhood Hits	35
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZN394_HUMAN
θ value	6.88961 (rank : 440)	NC score	-0.012833 (rank : 486)
Query Neighborhood Hits	455	Target Neighborhood Hits	752	Shared Neighborhood Hits	16
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.

CLR59_HUMAN
θ value	8.99809 (rank : 441)	NC score	0.309483 (rank : 280)
Query Neighborhood Hits	455	Target Neighborhood Hits	163	Shared Neighborhood Hits	141
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CO3A1_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.013531 (rank : 426)
Query Neighborhood Hits	455	Target Neighborhood Hits	452	Shared Neighborhood Hits	43
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	8.99809 (rank : 443)	NC score	0.013256 (rank : 428)
Query Neighborhood Hits	455	Target Neighborhood Hits	466	Shared Neighborhood Hits	40
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COIA1_MOUSE
θ value	8.99809 (rank : 444)	NC score	0.003491 (rank : 470)
Query Neighborhood Hits	455	Target Neighborhood Hits	481	Shared Neighborhood Hits	40
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CT012_MOUSE
θ value	8.99809 (rank : 445)	NC score	0.451139 (rank : 250)
Query Neighborhood Hits	455	Target Neighborhood Hits	229	Shared Neighborhood Hits	176
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

HCN2_HUMAN
θ value	8.99809 (rank : 446)	NC score	0.008800 (rank : 445)
Query Neighborhood Hits	455	Target Neighborhood Hits	369	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HDC_HUMAN
θ value	8.99809 (rank : 447)	NC score	0.006762 (rank : 455)
Query Neighborhood Hits	455	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBI9	Gene names	HECA, HDC
Domain Architecture	No domain graphic available
Description	Headcase protein homolog (hHDC).

HME2_HUMAN
θ value	8.99809 (rank : 448)	NC score	-0.008497 (rank : 482)
Query Neighborhood Hits	455	Target Neighborhood Hits	355	Shared Neighborhood Hits	4
SwissProt Accessions	P19622	Gene names	EN2
Domain Architecture
Description	Homeobox protein engrailed-2 (Hu-En-2).

MAGI2_HUMAN
θ value	8.99809 (rank : 449)	NC score	-0.000260 (rank : 477)
Query Neighborhood Hits	455	Target Neighborhood Hits	373	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MSH5_HUMAN
θ value	8.99809 (rank : 450)	NC score	0.004095 (rank : 468)
Query Neighborhood Hits	455	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.

MYO9B_HUMAN
θ value	8.99809 (rank : 451)	NC score	0.008242 (rank : 448)
Query Neighborhood Hits	455	Target Neighborhood Hits	641	Shared Neighborhood Hits	64
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PPRB_HUMAN
θ value	8.99809 (rank : 452)	NC score	0.022823 (rank : 381)
Query Neighborhood Hits	455	Target Neighborhood Hits	311	Shared Neighborhood Hits	30
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

RP1L1_HUMAN
θ value	8.99809 (rank : 453)	NC score	0.039917 (rank : 352)
Query Neighborhood Hits	455	Target Neighborhood Hits	1072	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TARSH_HUMAN
θ value	8.99809 (rank : 454)	NC score	0.023134 (rank : 380)
Query Neighborhood Hits	455	Target Neighborhood Hits	768	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TRPV2_MOUSE
θ value	8.99809 (rank : 455)	NC score	0.172244 (rank : 297)
Query Neighborhood Hits	455	Target Neighborhood Hits	111	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

ANKR9_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.228509 (rank : 292)
Query Neighborhood Hits	455	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.279279 (rank : 283)
Query Neighborhood Hits	455	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BAT4_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.241808 (rank : 291)
Query Neighborhood Hits	455	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.271454 (rank : 284)
Query Neighborhood Hits	455	Target Neighborhood Hits	171	Shared Neighborhood Hits	121
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CT012_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.409135 (rank : 261)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	164
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

CU081_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.125305 (rank : 300)
Query Neighborhood Hits	455	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

FADD_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.054845 (rank : 325)
Query Neighborhood Hits	455	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

FADD_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.060654 (rank : 321)
Query Neighborhood Hits	455	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

IKBL_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.327839 (rank : 278)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.320840 (rank : 279)
Query Neighborhood Hits	455	Target Neighborhood Hits	196	Shared Neighborhood Hits	140
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.050137 (rank : 336)
Query Neighborhood Hits	455	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

RELB_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.051190 (rank : 332)
Query Neighborhood Hits	455	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

RELB_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.051190 (rank : 333)
Query Neighborhood Hits	455	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

REL_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.052148 (rank : 329)
Query Neighborhood Hits	455	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

REL_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.053993 (rank : 327)
Query Neighborhood Hits	455	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

SMAP1_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.051288 (rank : 331)
Query Neighborhood Hits	455	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SPSB2_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.054401 (rank : 326)
Query Neighborhood Hits	455	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SSB4_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.055238 (rank : 324)
Query Neighborhood Hits	455	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

SSB4_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.050716 (rank : 335)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R5B6, Q8BJI9, Q8VHS8	Gene names	Spsb4, Ssb4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

TF65_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.051778 (rank : 330)
Query Neighborhood Hits	455	Target Neighborhood Hits	115	Shared Neighborhood Hits	17
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TF65_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.051081 (rank : 334)
Query Neighborhood Hits	455	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TRDN_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.052775 (rank : 328)
Query Neighborhood Hits	455	Target Neighborhood Hits	542	Shared Neighborhood Hits	36
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPC3_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.077756 (rank : 307)
Query Neighborhood Hits	455	Target Neighborhood Hits	131	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC4_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.061928 (rank : 318)
Query Neighborhood Hits	455	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.062039 (rank : 317)
Query Neighborhood Hits	455	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.063971 (rank : 315)
Query Neighborhood Hits	455	Target Neighborhood Hits	122	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.065402 (rank : 313)
Query Neighborhood Hits	455	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC7_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.070931 (rank : 311)
Query Neighborhood Hits	455	Target Neighborhood Hits	123	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.071494 (rank : 310)
Query Neighborhood Hits	455	Target Neighborhood Hits	114	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPV4_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.132322 (rank : 299)
Query Neighborhood Hits	455	Target Neighborhood Hits	150	Shared Neighborhood Hits	80
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.121731 (rank : 301)
Query Neighborhood Hits	455	Target Neighborhood Hits	117	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

Hits sorted by NC score

INVS_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	455
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
NC score	0.981358 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	455	Target Neighborhood Hits	609	Shared Neighborhood Hits	356
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR50_HUMAN
NC score	0.952126 (rank : 3)	θ value	2.41096e-53 (rank : 5)
Query Neighborhood Hits	455	Target Neighborhood Hits	361	Shared Neighborhood Hits	297
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR44_HUMAN
NC score	0.948816 (rank : 4)	θ value	3.0428e-56 (rank : 3)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	296
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR28_MOUSE
NC score	0.944648 (rank : 5)	θ value	2.75849e-49 (rank : 7)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	296
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR28_HUMAN
NC score	0.944091 (rank : 6)	θ value	1.788e-48 (rank : 8)
Query Neighborhood Hits	455	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_HUMAN
NC score	0.939845 (rank : 7)	θ value	1.32293e-51 (rank : 6)
Query Neighborhood Hits	455	Target Neighborhood Hits	322	Shared Neighborhood Hits	296
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
NC score	0.937826 (rank : 8)	θ value	1.01529e-43 (rank : 12)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	296
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR29_HUMAN
NC score	0.937627 (rank : 9)	θ value	4.15078e-21 (rank : 45)
Query Neighborhood Hits	455	Target Neighborhood Hits	294	Shared Neighborhood Hits	289
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

PSD10_HUMAN
NC score	0.934178 (rank : 10)	θ value	5.42112e-21 (rank : 46)
Query Neighborhood Hits	455	Target Neighborhood Hits	301	Shared Neighborhood Hits	290
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR16_HUMAN
NC score	0.933171 (rank : 11)	θ value	2.27762e-19 (rank : 51)
Query Neighborhood Hits	455	Target Neighborhood Hits	286	Shared Neighborhood Hits	280
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

PSD10_MOUSE
NC score	0.932812 (rank : 12)	θ value	2.69047e-20 (rank : 47)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	288
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANK1_HUMAN
NC score	0.932290 (rank : 13)	θ value	2.3352e-48 (rank : 9)
Query Neighborhood Hits	455	Target Neighborhood Hits	416	Shared Neighborhood Hits	302
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.930230 (rank : 14)	θ value	7.51208e-47 (rank : 11)
Query Neighborhood Hits	455	Target Neighborhood Hits	430	Shared Neighborhood Hits	299
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANKR6_HUMAN
NC score	0.925128 (rank : 15)	θ value	2.27762e-19 (rank : 50)
Query Neighborhood Hits	455	Target Neighborhood Hits	439	Shared Neighborhood Hits	301
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

TNKS1_HUMAN
NC score	0.924014 (rank : 16)	θ value	5.96599e-36 (rank : 14)
Query Neighborhood Hits	455	Target Neighborhood Hits	477	Shared Neighborhood Hits	309
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
NC score	0.922942 (rank : 17)	θ value	1.79631e-32 (rank : 17)
Query Neighborhood Hits	455	Target Neighborhood Hits	361	Shared Neighborhood Hits	295
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ASB3_MOUSE
NC score	0.922872 (rank : 18)	θ value	9.87957e-23 (rank : 34)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	292
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_HUMAN
NC score	0.922678 (rank : 19)	θ value	1.86321e-21 (rank : 44)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANK3_HUMAN
NC score	0.920632 (rank : 20)	θ value	3.98324e-48 (rank : 10)
Query Neighborhood Hits	455	Target Neighborhood Hits	853	Shared Neighborhood Hits	326
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

FANK1_HUMAN
NC score	0.919416 (rank : 21)	θ value	1.47631e-18 (rank : 55)
Query Neighborhood Hits	455	Target Neighborhood Hits	326	Shared Neighborhood Hits	286
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
NC score	0.918672 (rank : 22)	θ value	1.02238e-19 (rank : 49)
Query Neighborhood Hits	455	Target Neighborhood Hits	325	Shared Neighborhood Hits	284
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ASB7_MOUSE
NC score	0.915183 (rank : 23)	θ value	2.5182e-18 (rank : 56)
Query Neighborhood Hits	455	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.914906 (rank : 24)	θ value	3.28887e-18 (rank : 58)
Query Neighborhood Hits	455	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

TRPA1_MOUSE
NC score	0.914127 (rank : 25)	θ value	2.68423e-28 (rank : 21)
Query Neighborhood Hits	455	Target Neighborhood Hits	343	Shared Neighborhood Hits	290
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPA1_HUMAN
NC score	0.913580 (rank : 26)	θ value	2.05525e-28 (rank : 20)
Query Neighborhood Hits	455	Target Neighborhood Hits	339	Shared Neighborhood Hits	293
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ASB10_HUMAN
NC score	0.912218 (rank : 27)	θ value	1.09232e-21 (rank : 37)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANR42_MOUSE
NC score	0.911977 (rank : 28)	θ value	6.62687e-19 (rank : 53)
Query Neighborhood Hits	455	Target Neighborhood Hits	334	Shared Neighborhood Hits	282
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB10_MOUSE
NC score	0.911275 (rank : 29)	θ value	1.42661e-21 (rank : 40)
Query Neighborhood Hits	455	Target Neighborhood Hits	301	Shared Neighborhood Hits	284
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB2_HUMAN
NC score	0.909621 (rank : 30)	θ value	3.51386e-20 (rank : 48)
Query Neighborhood Hits	455	Target Neighborhood Hits	309	Shared Neighborhood Hits	286
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR23_MOUSE
NC score	0.908475 (rank : 31)	θ value	3.63628e-17 (rank : 63)
Query Neighborhood Hits	455	Target Neighborhood Hits	296	Shared Neighborhood Hits	285
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR23_HUMAN
NC score	0.908449 (rank : 32)	θ value	9.56915e-18 (rank : 62)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	284
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANKR2_MOUSE
NC score	0.907833 (rank : 33)	θ value	8.10077e-17 (rank : 66)
Query Neighborhood Hits	455	Target Neighborhood Hits	312	Shared Neighborhood Hits	286
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR2_HUMAN
NC score	0.906966 (rank : 34)	θ value	1.058e-16 (rank : 67)
Query Neighborhood Hits	455	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR42_HUMAN
NC score	0.905950 (rank : 35)	θ value	7.58209e-15 (rank : 83)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB8_MOUSE
NC score	0.901304 (rank : 36)	θ value	3.76295e-14 (rank : 89)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANKR1_HUMAN
NC score	0.900875 (rank : 37)	θ value	6.20254e-17 (rank : 65)
Query Neighborhood Hits	455	Target Neighborhood Hits	308	Shared Neighborhood Hits	279
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ASB8_HUMAN
NC score	0.900794 (rank : 38)	θ value	8.38298e-14 (rank : 94)
Query Neighborhood Hits	455	Target Neighborhood Hits	294	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB2_MOUSE
NC score	0.900713 (rank : 39)	θ value	2.88119e-14 (rank : 87)
Query Neighborhood Hits	455	Target Neighborhood Hits	321	Shared Neighborhood Hits	283
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANKR1_MOUSE
NC score	0.899561 (rank : 40)	θ value	7.32683e-18 (rank : 61)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	284
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB13_MOUSE
NC score	0.899505 (rank : 41)	θ value	8.95645e-16 (rank : 75)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_HUMAN
NC score	0.899173 (rank : 42)	θ value	8.95645e-16 (rank : 74)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	285
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANR39_HUMAN
NC score	0.894036 (rank : 43)	θ value	6.00763e-12 (rank : 127)
Query Neighborhood Hits	455	Target Neighborhood Hits	285	Shared Neighborhood Hits	278
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB15_HUMAN
NC score	0.893567 (rank : 44)	θ value	3.62785e-25 (rank : 24)
Query Neighborhood Hits	455	Target Neighborhood Hits	305	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANR39_MOUSE
NC score	0.892263 (rank : 45)	θ value	2.0648e-12 (rank : 122)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

BCL3_HUMAN
NC score	0.891029 (rank : 46)	θ value	1.99529e-15 (rank : 78)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	282
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

BCL3_MOUSE
NC score	0.885968 (rank : 47)	θ value	2.60593e-15 (rank : 79)
Query Neighborhood Hits	455	Target Neighborhood Hits	388	Shared Neighborhood Hits	289
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANKS6_HUMAN
NC score	0.884785 (rank : 48)	θ value	3.07829e-16 (rank : 70)
Query Neighborhood Hits	455	Target Neighborhood Hits	411	Shared Neighborhood Hits	302
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKS6_MOUSE
NC score	0.884400 (rank : 49)	θ value	5.8054e-15 (rank : 81)
Query Neighborhood Hits	455	Target Neighborhood Hits	435	Shared Neighborhood Hits	300
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

GABP2_MOUSE
NC score	0.883599 (rank : 50)	θ value	1.02475e-11 (rank : 132)
Query Neighborhood Hits	455	Target Neighborhood Hits	429	Shared Neighborhood Hits	289
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANKS1_HUMAN
NC score	0.882641 (rank : 51)	θ value	1.5242e-23 (rank : 29)
Query Neighborhood Hits	455	Target Neighborhood Hits	438	Shared Neighborhood Hits	293
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ASB15_MOUSE
NC score	0.882479 (rank : 52)	θ value	1.99067e-23 (rank : 31)
Query Neighborhood Hits	455	Target Neighborhood Hits	292	Shared Neighborhood Hits	270
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANKR7_HUMAN
NC score	0.882343 (rank : 53)	θ value	2.43908e-13 (rank : 105)
Query Neighborhood Hits	455	Target Neighborhood Hits	286	Shared Neighborhood Hits	277
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

GABP2_HUMAN
NC score	0.881522 (rank : 54)	θ value	6.00763e-12 (rank : 129)
Query Neighborhood Hits	455	Target Neighborhood Hits	454	Shared Neighborhood Hits	288
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ASB14_MOUSE
NC score	0.881472 (rank : 55)	θ value	5.60996e-18 (rank : 60)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

PA2G6_MOUSE
NC score	0.881168 (rank : 56)	θ value	3.18553e-13 (rank : 111)
Query Neighborhood Hits	455	Target Neighborhood Hits	293	Shared Neighborhood Hits	282
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANKS3_MOUSE
NC score	0.880600 (rank : 57)	θ value	3.18553e-13 (rank : 106)
Query Neighborhood Hits	455	Target Neighborhood Hits	355	Shared Neighborhood Hits	278
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

PA2G6_HUMAN
NC score	0.880092 (rank : 58)	θ value	9.90251e-15 (rank : 84)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR49_MOUSE
NC score	0.879145 (rank : 59)	θ value	3.64472e-09 (rank : 167)
Query Neighborhood Hits	455	Target Neighborhood Hits	285	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

GABP3_MOUSE
NC score	0.878380 (rank : 60)	θ value	7.34386e-10 (rank : 159)
Query Neighborhood Hits	455	Target Neighborhood Hits	330	Shared Neighborhood Hits	280
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANKR5_HUMAN
NC score	0.877800 (rank : 61)	θ value	2.20605e-14 (rank : 86)
Query Neighborhood Hits	455	Target Neighborhood Hits	297	Shared Neighborhood Hits	283
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS3_HUMAN
NC score	0.877796 (rank : 62)	θ value	1.58096e-12 (rank : 117)
Query Neighborhood Hits	455	Target Neighborhood Hits	355	Shared Neighborhood Hits	281
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

MIB1_HUMAN
NC score	0.877107 (rank : 63)	θ value	1.09232e-21 (rank : 38)
Query Neighborhood Hits	455	Target Neighborhood Hits	470	Shared Neighborhood Hits	291
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.876722 (rank : 64)	θ value	1.09232e-21 (rank : 39)
Query Neighborhood Hits	455	Target Neighborhood Hits	471	Shared Neighborhood Hits	291
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANKR5_MOUSE
NC score	0.875240 (rank : 65)	θ value	2.43908e-13 (rank : 104)
Query Neighborhood Hits	455	Target Neighborhood Hits	298	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR49_HUMAN
NC score	0.875092 (rank : 66)	θ value	6.21693e-09 (rank : 169)
Query Neighborhood Hits	455	Target Neighborhood Hits	282	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

CDN2C_HUMAN
NC score	0.875002 (rank : 67)	θ value	1.33837e-11 (rank : 135)
Query Neighborhood Hits	455	Target Neighborhood Hits	262	Shared Neighborhood Hits	262
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2C_MOUSE
NC score	0.874230 (rank : 68)	θ value	1.33837e-11 (rank : 136)
Query Neighborhood Hits	455	Target Neighborhood Hits	270	Shared Neighborhood Hits	267
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANK2_HUMAN
NC score	0.873553 (rank : 69)	θ value	8.28633e-54 (rank : 4)
Query Neighborhood Hits	455	Target Neighborhood Hits	1615	Shared Neighborhood Hits	381
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASZ1_MOUSE
NC score	0.872990 (rank : 70)	θ value	8.38298e-14 (rank : 95)
Query Neighborhood Hits	455	Target Neighborhood Hits	319	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB16_MOUSE
NC score	0.872889 (rank : 71)	θ value	8.67504e-11 (rank : 148)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

MIB2_HUMAN
NC score	0.872608 (rank : 72)	θ value	4.43474e-23 (rank : 33)
Query Neighborhood Hits	455	Target Neighborhood Hits	438	Shared Neighborhood Hits	290
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
NC score	0.872466 (rank : 73)	θ value	2.59989e-23 (rank : 32)
Query Neighborhood Hits	455	Target Neighborhood Hits	409	Shared Neighborhood Hits	282
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ASZ1_HUMAN
NC score	0.871615 (rank : 74)	θ value	1.42992e-13 (rank : 97)
Query Neighborhood Hits	455	Target Neighborhood Hits	341	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANKS1_MOUSE
NC score	0.871560 (rank : 75)	θ value	1.29031e-22 (rank : 35)
Query Neighborhood Hits	455	Target Neighborhood Hits	453	Shared Neighborhood Hits	294
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

MTPN_MOUSE
NC score	0.868415 (rank : 76)	θ value	3.41135e-07 (rank : 197)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANRA2_HUMAN
NC score	0.867381 (rank : 77)	θ value	9.26847e-13 (rank : 114)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	277
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
NC score	0.866898 (rank : 78)	θ value	4.16044e-13 (rank : 112)
Query Neighborhood Hits	455	Target Neighborhood Hits	287	Shared Neighborhood Hits	277
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB9_HUMAN
NC score	0.866494 (rank : 79)	θ value	4.44505e-15 (rank : 80)
Query Neighborhood Hits	455	Target Neighborhood Hits	267	Shared Neighborhood Hits	257
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASB16_HUMAN
NC score	0.866467 (rank : 80)	θ value	1.25267e-09 (rank : 162)
Query Neighborhood Hits	455	Target Neighborhood Hits	286	Shared Neighborhood Hits	270
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

MTPN_HUMAN
NC score	0.863760 (rank : 81)	θ value	9.92553e-07 (rank : 202)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ASB11_HUMAN
NC score	0.863027 (rank : 82)	θ value	1.29331e-14 (rank : 85)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

RFXK_HUMAN
NC score	0.862676 (rank : 83)	θ value	8.67504e-11 (rank : 151)
Query Neighborhood Hits	455	Target Neighborhood Hits	282	Shared Neighborhood Hits	266
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ASB11_MOUSE
NC score	0.862151 (rank : 84)	θ value	9.26847e-13 (rank : 115)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB5_HUMAN
NC score	0.861474 (rank : 85)	θ value	8.38298e-14 (rank : 93)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	270
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

MYPT1_MOUSE
NC score	0.860070 (rank : 86)	θ value	4.91457e-14 (rank : 91)
Query Neighborhood Hits	455	Target Neighborhood Hits	539	Shared Neighborhood Hits	297
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

AN36B_HUMAN
NC score	0.859546 (rank : 87)	θ value	2.28291e-11 (rank : 140)
Query Neighborhood Hits	455	Target Neighborhood Hits	294	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

EHMT1_HUMAN
NC score	0.859057 (rank : 88)	θ value	1.5242e-23 (rank : 30)
Query Neighborhood Hits	455	Target Neighborhood Hits	417	Shared Neighborhood Hits	301
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

PP16A_MOUSE
NC score	0.858583 (rank : 89)	θ value	1.02475e-11 (rank : 133)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	285
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2D_HUMAN
NC score	0.858184 (rank : 90)	θ value	6.87365e-08 (rank : 182)
Query Neighborhood Hits	455	Target Neighborhood Hits	268	Shared Neighborhood Hits	266
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB4_MOUSE
NC score	0.856799 (rank : 91)	θ value	1.58096e-12 (rank : 119)
Query Neighborhood Hits	455	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB5_MOUSE
NC score	0.856433 (rank : 92)	θ value	1.58096e-12 (rank : 120)
Query Neighborhood Hits	455	Target Neighborhood Hits	266	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB4_HUMAN
NC score	0.856259 (rank : 93)	θ value	1.133e-10 (rank : 152)
Query Neighborhood Hits	455	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

RFXK_MOUSE
NC score	0.855383 (rank : 94)	θ value	6.64225e-11 (rank : 147)
Query Neighborhood Hits	455	Target Neighborhood Hits	273	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB12_HUMAN
NC score	0.854117 (rank : 95)	θ value	3.18553e-13 (rank : 107)
Query Neighborhood Hits	455	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB9_MOUSE
NC score	0.852924 (rank : 96)	θ value	4.59992e-12 (rank : 124)
Query Neighborhood Hits	455	Target Neighborhood Hits	257	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

RN5A_HUMAN
NC score	0.852726 (rank : 97)	θ value	1.86753e-13 (rank : 101)
Query Neighborhood Hits	455	Target Neighborhood Hits	608	Shared Neighborhood Hits	282
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

CSKI2_MOUSE
NC score	0.852322 (rank : 98)	θ value	2.5182e-18 (rank : 57)
Query Neighborhood Hits	455	Target Neighborhood Hits	812	Shared Neighborhood Hits	322
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PP16B_HUMAN
NC score	0.851085 (rank : 99)	θ value	4.59992e-12 (rank : 126)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	281
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

CSKI1_HUMAN
NC score	0.850967 (rank : 100)	θ value	1.80048e-24 (rank : 26)
Query Neighborhood Hits	455	Target Neighborhood Hits	997	Shared Neighborhood Hits	337
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
NC score	0.850711 (rank : 101)	θ value	4.29542e-18 (rank : 59)
Query Neighborhood Hits	455	Target Neighborhood Hits	747	Shared Neighborhood Hits	312
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PP16A_HUMAN
NC score	0.850248 (rank : 102)	θ value	9.59137e-10 (rank : 161)
Query Neighborhood Hits	455	Target Neighborhood Hits	340	Shared Neighborhood Hits	283
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR46_HUMAN
NC score	0.849639 (rank : 103)	θ value	1.17247e-07 (rank : 185)
Query Neighborhood Hits	455	Target Neighborhood Hits	281	Shared Neighborhood Hits	274
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

CDN2D_MOUSE
NC score	0.849589 (rank : 104)	θ value	4.92598e-06 (rank : 208)
Query Neighborhood Hits	455	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANR22_HUMAN
NC score	0.849583 (rank : 105)	θ value	5.81887e-07 (rank : 198)
Query Neighborhood Hits	455	Target Neighborhood Hits	243	Shared Neighborhood Hits	240
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

CSKI1_MOUSE
NC score	0.849085 (rank : 106)	θ value	2.35151e-24 (rank : 27)
Query Neighborhood Hits	455	Target Neighborhood Hits	1031	Shared Neighborhood Hits	327
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EHMT2_HUMAN
NC score	0.849051 (rank : 107)	θ value	1.37858e-24 (rank : 25)
Query Neighborhood Hits	455	Target Neighborhood Hits	498	Shared Neighborhood Hits	303
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PP16B_MOUSE
NC score	0.849026 (rank : 108)	θ value	1.02475e-11 (rank : 134)
Query Neighborhood Hits	455	Target Neighborhood Hits	302	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ASB12_MOUSE
NC score	0.848888 (rank : 109)	θ value	6.00763e-12 (rank : 128)
Query Neighborhood Hits	455	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

IKBA_HUMAN
NC score	0.848123 (rank : 110)	θ value	8.97725e-08 (rank : 184)
Query Neighborhood Hits	455	Target Neighborhood Hits	280	Shared Neighborhood Hits	272
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANR10_HUMAN
NC score	0.844838 (rank : 111)	θ value	3.08544e-08 (rank : 176)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR10_MOUSE
NC score	0.844344 (rank : 112)	θ value	1.63604e-09 (rank : 164)
Query Neighborhood Hits	455	Target Neighborhood Hits	273	Shared Neighborhood Hits	262
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR46_MOUSE
NC score	0.844201 (rank : 113)	θ value	1.53129e-07 (rank : 187)
Query Neighborhood Hits	455	Target Neighborhood Hits	274	Shared Neighborhood Hits	268
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASB1_HUMAN
NC score	0.842682 (rank : 114)	θ value	9.59137e-10 (rank : 160)
Query Neighborhood Hits	455	Target Neighborhood Hits	291	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

IKBE_MOUSE
NC score	0.841901 (rank : 115)	θ value	6.21693e-09 (rank : 170)
Query Neighborhood Hits	455	Target Neighborhood Hits	308	Shared Neighborhood Hits	274
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

MYPT2_HUMAN
NC score	0.841484 (rank : 116)	θ value	1.74796e-11 (rank : 139)
Query Neighborhood Hits	455	Target Neighborhood Hits	707	Shared Neighborhood Hits	300
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANR35_HUMAN
NC score	0.841400 (rank : 117)	θ value	6.62687e-19 (rank : 52)
Query Neighborhood Hits	455	Target Neighborhood Hits	784	Shared Neighborhood Hits	297
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB1_MOUSE
NC score	0.840385 (rank : 118)	θ value	3.64472e-09 (rank : 168)
Query Neighborhood Hits	455	Target Neighborhood Hits	292	Shared Neighborhood Hits	272
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

MYPT1_HUMAN
NC score	0.839124 (rank : 119)	θ value	4.91457e-14 (rank : 90)
Query Neighborhood Hits	455	Target Neighborhood Hits	723	Shared Neighborhood Hits	291
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

CT086_HUMAN
NC score	0.836932 (rank : 120)	θ value	0.00509761 (rank : 252)
Query Neighborhood Hits	455	Target Neighborhood Hits	277	Shared Neighborhood Hits	272
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

EHMT2_MOUSE
NC score	0.836877 (rank : 121)	θ value	1.24688e-25 (rank : 22)
Query Neighborhood Hits	455	Target Neighborhood Hits	750	Shared Neighborhood Hits	339
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

IKBA_MOUSE
NC score	0.836039 (rank : 122)	θ value	1.99992e-07 (rank : 192)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

POTE8_HUMAN
NC score	0.834274 (rank : 123)	θ value	2.0648e-12 (rank : 123)
Query Neighborhood Hits	455	Target Neighborhood Hits	337	Shared Neighborhood Hits	282
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANR19_HUMAN
NC score	0.833317 (rank : 124)	θ value	1.58096e-12 (rank : 118)
Query Neighborhood Hits	455	Target Neighborhood Hits	276	Shared Neighborhood Hits	270
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ACBD6_MOUSE
NC score	0.833250 (rank : 125)	θ value	5.62301e-10 (rank : 156)
Query Neighborhood Hits	455	Target Neighborhood Hits	305	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANFY1_MOUSE
NC score	0.829984 (rank : 126)	θ value	1.62847e-25 (rank : 23)
Query Neighborhood Hits	455	Target Neighborhood Hits	480	Shared Neighborhood Hits	289
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ACBD6_HUMAN
NC score	0.827913 (rank : 127)	θ value	3.64472e-09 (rank : 166)
Query Neighborhood Hits	455	Target Neighborhood Hits	304	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANFY1_HUMAN
NC score	0.827399 (rank : 128)	θ value	1.86321e-21 (rank : 43)
Query Neighborhood Hits	455	Target Neighborhood Hits	480	Shared Neighborhood Hits	286
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

BARD1_HUMAN
NC score	0.827237 (rank : 129)	θ value	2.98157e-11 (rank : 143)
Query Neighborhood Hits	455	Target Neighborhood Hits	427	Shared Neighborhood Hits	285
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

AN36A_HUMAN
NC score	0.826645 (rank : 130)	θ value	2.13673e-09 (rank : 165)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	264
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

BARD1_MOUSE
NC score	0.826546 (rank : 131)	θ value	1.133e-10 (rank : 153)
Query Neighborhood Hits	455	Target Neighborhood Hits	411	Shared Neighborhood Hits	281
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

IKBE_HUMAN
NC score	0.817171 (rank : 132)	θ value	2.21117e-06 (rank : 205)
Query Neighborhood Hits	455	Target Neighborhood Hits	288	Shared Neighborhood Hits	268
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

IKBB_HUMAN
NC score	0.815746 (rank : 133)	θ value	1.80886e-08 (rank : 174)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBB_MOUSE
NC score	0.812602 (rank : 134)	θ value	1.17247e-07 (rank : 186)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

RN5A_MOUSE
NC score	0.802108 (rank : 135)	θ value	1.52774e-15 (rank : 77)
Query Neighborhood Hits	455	Target Neighborhood Hits	899	Shared Neighborhood Hits	297
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

USH1G_MOUSE
NC score	0.799638 (rank : 136)	θ value	2.61198e-07 (rank : 196)
Query Neighborhood Hits	455	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.799572 (rank : 137)	θ value	2.61198e-07 (rank : 195)
Query Neighborhood Hits	455	Target Neighborhood Hits	267	Shared Neighborhood Hits	261
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ANS4B_HUMAN
NC score	0.799239 (rank : 138)	θ value	8.11959e-09 (rank : 171)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	259
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH17_HUMAN
NC score	0.796949 (rank : 139)	θ value	4.02038e-16 (rank : 72)
Query Neighborhood Hits	455	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR32_HUMAN
NC score	0.794331 (rank : 140)	θ value	3.19293e-05 (rank : 218)
Query Neighborhood Hits	455	Target Neighborhood Hits	270	Shared Neighborhood Hits	260
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ZDH17_MOUSE
NC score	0.791949 (rank : 141)	θ value	6.85773e-16 (rank : 73)
Query Neighborhood Hits	455	Target Neighborhood Hits	328	Shared Neighborhood Hits	275
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ZDH13_HUMAN
NC score	0.789307 (rank : 142)	θ value	1.09485e-13 (rank : 96)
Query Neighborhood Hits	455	Target Neighborhood Hits	322	Shared Neighborhood Hits	274
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANS4B_MOUSE
NC score	0.786977 (rank : 143)	θ value	7.59969e-07 (rank : 200)
Query Neighborhood Hits	455	Target Neighborhood Hits	294	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

POT15_HUMAN
NC score	0.786008 (rank : 144)	θ value	1.52774e-15 (rank : 76)
Query Neighborhood Hits	455	Target Neighborhood Hits	893	Shared Neighborhood Hits	301
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANR21_HUMAN
NC score	0.785887 (rank : 145)	θ value	1.80466e-16 (rank : 69)
Query Neighborhood Hits	455	Target Neighborhood Hits	864	Shared Neighborhood Hits	302
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANKY2_HUMAN
NC score	0.785856 (rank : 146)	θ value	2.36244e-08 (rank : 175)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	262
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ZDH13_MOUSE
NC score	0.785353 (rank : 147)	θ value	1.86753e-13 (rank : 102)
Query Neighborhood Hits	455	Target Neighborhood Hits	329	Shared Neighborhood Hits	277
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANR41_HUMAN
NC score	0.784752 (rank : 148)	θ value	3.77169e-06 (rank : 206)
Query Neighborhood Hits	455	Target Neighborhood Hits	332	Shared Neighborhood Hits	256
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR32_MOUSE
NC score	0.783566 (rank : 149)	θ value	4.1701e-05 (rank : 221)
Query Neighborhood Hits	455	Target Neighborhood Hits	285	Shared Neighborhood Hits	260
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

CTTB2_HUMAN
NC score	0.780451 (rank : 150)	θ value	3.07829e-16 (rank : 71)
Query Neighborhood Hits	455	Target Neighborhood Hits	1061	Shared Neighborhood Hits	306
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

POT14_HUMAN
NC score	0.773689 (rank : 151)	θ value	8.67504e-11 (rank : 150)
Query Neighborhood Hits	455	Target Neighborhood Hits	403	Shared Neighborhood Hits	278
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANR15_HUMAN
NC score	0.773372 (rank : 152)	θ value	2.52405e-10 (rank : 155)
Query Neighborhood Hits	455	Target Neighborhood Hits	478	Shared Neighborhood Hits	272
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR11_HUMAN
NC score	0.772109 (rank : 153)	θ value	2.28291e-11 (rank : 141)
Query Neighborhood Hits	455	Target Neighborhood Hits	1289	Shared Neighborhood Hits	327
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR47_MOUSE
NC score	0.767640 (rank : 154)	θ value	1.53129e-07 (rank : 188)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB6_HUMAN
NC score	0.764403 (rank : 155)	θ value	0.00390308 (rank : 250)
Query Neighborhood Hits	455	Target Neighborhood Hits	256	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

NFKB1_HUMAN
NC score	0.762687 (rank : 156)	θ value	1.58096e-12 (rank : 121)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB1_MOUSE
NC score	0.761407 (rank : 157)	θ value	8.67504e-11 (rank : 149)
Query Neighborhood Hits	455	Target Neighborhood Hits	300	Shared Neighborhood Hits	272
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ASB6_MOUSE
NC score	0.760510 (rank : 158)	θ value	0.00665767 (rank : 257)
Query Neighborhood Hits	455	Target Neighborhood Hits	264	Shared Neighborhood Hits	244
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANKY2_MOUSE
NC score	0.760333 (rank : 159)	θ value	6.87365e-08 (rank : 180)
Query Neighborhood Hits	455	Target Neighborhood Hits	316	Shared Neighborhood Hits	256
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR37_HUMAN
NC score	0.758922 (rank : 160)	θ value	3.19293e-05 (rank : 219)
Query Neighborhood Hits	455	Target Neighborhood Hits	247	Shared Neighborhood Hits	242
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

SNCAP_HUMAN
NC score	0.757985 (rank : 161)	θ value	3.77169e-06 (rank : 207)
Query Neighborhood Hits	455	Target Neighborhood Hits	313	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

NFKB2_HUMAN
NC score	0.757917 (rank : 162)	θ value	6.64225e-11 (rank : 145)
Query Neighborhood Hits	455	Target Neighborhood Hits	325	Shared Neighborhood Hits	280
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR47_HUMAN
NC score	0.749463 (rank : 163)	θ value	6.87365e-08 (rank : 181)
Query Neighborhood Hits	455	Target Neighborhood Hits	369	Shared Neighborhood Hits	265
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR33_MOUSE
NC score	0.745937 (rank : 164)	θ value	1.69304e-06 (rank : 203)
Query Neighborhood Hits	455	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR12_HUMAN
NC score	0.743184 (rank : 165)	θ value	6.64225e-11 (rank : 144)
Query Neighborhood Hits	455	Target Neighborhood Hits	1081	Shared Neighborhood Hits	311
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

SHAN1_HUMAN
NC score	0.742661 (rank : 166)	θ value	1.47974e-10 (rank : 154)
Query Neighborhood Hits	455	Target Neighborhood Hits	1041	Shared Neighborhood Hits	301
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

NFKB2_MOUSE
NC score	0.741633 (rank : 167)	θ value	6.64225e-11 (rank : 146)
Query Neighborhood Hits	455	Target Neighborhood Hits	326	Shared Neighborhood Hits	274
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

BCOR_MOUSE
NC score	0.736408 (rank : 168)	θ value	7.59969e-07 (rank : 201)
Query Neighborhood Hits	455	Target Neighborhood Hits	521	Shared Neighborhood Hits	287
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR37_MOUSE
NC score	0.736084 (rank : 169)	θ value	2.44474e-05 (rank : 215)
Query Neighborhood Hits	455	Target Neighborhood Hits	237	Shared Neighborhood Hits	232
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR33_HUMAN
NC score	0.733596 (rank : 170)	θ value	8.40245e-06 (rank : 211)
Query Neighborhood Hits	455	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

BCOR_HUMAN
NC score	0.729767 (rank : 171)	θ value	5.81887e-07 (rank : 199)
Query Neighborhood Hits	455	Target Neighborhood Hits	609	Shared Neighborhood Hits	298
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR25_HUMAN
NC score	0.729746 (rank : 172)	θ value	1.06045e-08 (rank : 172)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	268
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

POT22_HUMAN
NC score	0.729279 (rank : 173)	θ value	4.0297e-08 (rank : 179)
Query Neighborhood Hits	455	Target Neighborhood Hits	266	Shared Neighborhood Hits	255
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

A20A3_HUMAN
NC score	0.721047 (rank : 174)	θ value	1.86753e-13 (rank : 99)
Query Neighborhood Hits	455	Target Neighborhood Hits	692	Shared Neighborhood Hits	280
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.720062 (rank : 175)	θ value	2.43908e-13 (rank : 103)
Query Neighborhood Hits	455	Target Neighborhood Hits	716	Shared Neighborhood Hits	280
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

KRIT1_MOUSE
NC score	0.719976 (rank : 176)	θ value	6.87365e-08 (rank : 183)
Query Neighborhood Hits	455	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

CLPB_MOUSE
NC score	0.719553 (rank : 177)	θ value	6.43352e-06 (rank : 210)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	250
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

A20A1_HUMAN
NC score	0.718622 (rank : 178)	θ value	1.86753e-13 (rank : 98)
Query Neighborhood Hits	455	Target Neighborhood Hits	698	Shared Neighborhood Hits	276
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

MPP8_HUMAN
NC score	0.717121 (rank : 179)	θ value	4.59992e-12 (rank : 125)
Query Neighborhood Hits	455	Target Neighborhood Hits	948	Shared Neighborhood Hits	280
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

A20A4_HUMAN
NC score	0.715878 (rank : 180)	θ value	1.86753e-13 (rank : 100)
Query Neighborhood Hits	455	Target Neighborhood Hits	710	Shared Neighborhood Hits	280
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR25_MOUSE
NC score	0.715626 (rank : 181)	θ value	3.08544e-08 (rank : 177)
Query Neighborhood Hits	455	Target Neighborhood Hits	398	Shared Neighborhood Hits	271
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CD2A1_MOUSE
NC score	0.714394 (rank : 182)	θ value	0.0113563 (rank : 271)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	204
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ANR38_HUMAN
NC score	0.710324 (rank : 183)	θ value	1.99992e-07 (rank : 190)
Query Neighborhood Hits	455	Target Neighborhood Hits	443	Shared Neighborhood Hits	247
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

KRIT1_HUMAN
NC score	0.709863 (rank : 184)	θ value	2.61198e-07 (rank : 194)
Query Neighborhood Hits	455	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

OSBL1_HUMAN
NC score	0.697852 (rank : 185)	θ value	6.00763e-12 (rank : 131)
Query Neighborhood Hits	455	Target Neighborhood Hits	368	Shared Neighborhood Hits	280
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
NC score	0.686353 (rank : 186)	θ value	2.28291e-11 (rank : 142)
Query Neighborhood Hits	455	Target Neighborhood Hits	336	Shared Neighborhood Hits	278
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR38_MOUSE
NC score	0.685996 (rank : 187)	θ value	2.61198e-07 (rank : 193)
Query Neighborhood Hits	455	Target Neighborhood Hits	512	Shared Neighborhood Hits	248
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSTF1_MOUSE
NC score	0.682712 (rank : 188)	θ value	4.0297e-08 (rank : 178)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	260
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

RAI14_HUMAN
NC score	0.682338 (rank : 189)	θ value	3.75424e-22 (rank : 36)
Query Neighborhood Hits	455	Target Neighborhood Hits	1367	Shared Neighborhood Hits	314
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

CDN2B_MOUSE
NC score	0.675418 (rank : 190)	θ value	0.0148317 (rank : 276)
Query Neighborhood Hits	455	Target Neighborhood Hits	201	Shared Neighborhood Hits	198
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

OSTF1_HUMAN
NC score	0.667080 (rank : 191)	θ value	1.38499e-08 (rank : 173)
Query Neighborhood Hits	455	Target Neighborhood Hits	466	Shared Neighborhood Hits	257
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR18_HUMAN
NC score	0.665792 (rank : 192)	θ value	7.58209e-15 (rank : 82)
Query Neighborhood Hits	455	Target Neighborhood Hits	1106	Shared Neighborhood Hits	283
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR45_MOUSE
NC score	0.650293 (rank : 193)	θ value	8.40245e-06 (rank : 212)
Query Neighborhood Hits	455	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

RAI14_MOUSE
NC score	0.648378 (rank : 194)	θ value	5.23862e-24 (rank : 28)
Query Neighborhood Hits	455	Target Neighborhood Hits	1505	Shared Neighborhood Hits	325
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CD2A1_HUMAN
NC score	0.633335 (rank : 195)	θ value	0.47712 (rank : 324)
Query Neighborhood Hits	455	Target Neighborhood Hits	196	Shared Neighborhood Hits	192
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANR43_HUMAN
NC score	0.630297 (rank : 196)	θ value	0.0113563 (rank : 269)
Query Neighborhood Hits	455	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

AN30A_HUMAN
NC score	0.628790 (rank : 197)	θ value	1.2105e-12 (rank : 116)
Query Neighborhood Hits	455	Target Neighborhood Hits	1119	Shared Neighborhood Hits	298
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CDN2B_HUMAN
NC score	0.627279 (rank : 198)	θ value	0.0563607 (rank : 293)
Query Neighborhood Hits	455	Target Neighborhood Hits	196	Shared Neighborhood Hits	195
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CLPB_HUMAN
NC score	0.625558 (rank : 199)	θ value	0.000270298 (rank : 228)
Query Neighborhood Hits	455	Target Neighborhood Hits	265	Shared Neighborhood Hits	235
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR43_MOUSE
NC score	0.622068 (rank : 200)	θ value	0.0113563 (rank : 270)
Query Neighborhood Hits	455	Target Neighborhood Hits	214	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

HECD1_HUMAN
NC score	0.621722 (rank : 201)	θ value	9.29e-05 (rank : 222)
Query Neighborhood Hits	455	Target Neighborhood Hits	371	Shared Neighborhood Hits	271
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ABTB2_HUMAN
NC score	0.611783 (rank : 202)	θ value	4.1701e-05 (rank : 220)
Query Neighborhood Hits	455	Target Neighborhood Hits	391	Shared Neighborhood Hits	238
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR45_HUMAN
NC score	0.607657 (rank : 203)	θ value	0.00035302 (rank : 230)
Query Neighborhood Hits	455	Target Neighborhood Hits	201	Shared Neighborhood Hits	186
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANKK1_HUMAN
NC score	0.603394 (rank : 204)	θ value	3.16345e-37 (rank : 13)
Query Neighborhood Hits	455	Target Neighborhood Hits	1075	Shared Neighborhood Hits	301
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ASB14_HUMAN
NC score	0.601214 (rank : 205)	θ value	1.69304e-06 (rank : 204)
Query Neighborhood Hits	455	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ABTB2_MOUSE
NC score	0.601142 (rank : 206)	θ value	3.19293e-05 (rank : 217)
Query Neighborhood Hits	455	Target Neighborhood Hits	414	Shared Neighborhood Hits	238
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

NUD12_MOUSE
NC score	0.595933 (rank : 207)	θ value	0.00509761 (rank : 255)
Query Neighborhood Hits	455	Target Neighborhood Hits	243	Shared Neighborhood Hits	222
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

RIPK4_HUMAN
NC score	0.594016 (rank : 208)	θ value	9.52487e-34 (rank : 16)
Query Neighborhood Hits	455	Target Neighborhood Hits	1094	Shared Neighborhood Hits	309
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKY1_HUMAN
NC score	0.592254 (rank : 209)	θ value	0.00869519 (rank : 263)
Query Neighborhood Hits	455	Target Neighborhood Hits	248	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANKK1_MOUSE
NC score	0.587591 (rank : 210)	θ value	9.52487e-34 (rank : 15)
Query Neighborhood Hits	455	Target Neighborhood Hits	1072	Shared Neighborhood Hits	301
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR40_HUMAN
NC score	0.582936 (rank : 211)	θ value	1.06291 (rank : 333)
Query Neighborhood Hits	455	Target Neighborhood Hits	224	Shared Neighborhood Hits	200
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

TRPV6_MOUSE
NC score	0.581947 (rank : 212)	θ value	4.92598e-06 (rank : 209)
Query Neighborhood Hits	455	Target Neighborhood Hits	284	Shared Neighborhood Hits	252
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR40_MOUSE
NC score	0.577465 (rank : 213)	θ value	3.0926 (rank : 375)
Query Neighborhood Hits	455	Target Neighborhood Hits	228	Shared Neighborhood Hits	202
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ASPP2_HUMAN
NC score	0.572800 (rank : 214)	θ value	0.000461057 (rank : 234)
Query Neighborhood Hits	455	Target Neighborhood Hits	1156	Shared Neighborhood Hits	307
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

IASPP_HUMAN
NC score	0.569313 (rank : 215)	θ value	0.00035302 (rank : 232)
Query Neighborhood Hits	455	Target Neighborhood Hits	688	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CENB5_HUMAN
NC score	0.568333 (rank : 216)	θ value	2.44474e-05 (rank : 216)
Query Neighborhood Hits	455	Target Neighborhood Hits	395	Shared Neighborhood Hits	263
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

NUD12_HUMAN
NC score	0.566952 (rank : 217)	θ value	0.00509761 (rank : 254)
Query Neighborhood Hits	455	Target Neighborhood Hits	222	Shared Neighborhood Hits	203
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CENB1_HUMAN
NC score	0.566518 (rank : 218)	θ value	1.09739e-05 (rank : 213)
Query Neighborhood Hits	455	Target Neighborhood Hits	383	Shared Neighborhood Hits	258
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
NC score	0.560313 (rank : 219)	θ value	1.99992e-07 (rank : 191)
Query Neighborhood Hits	455	Target Neighborhood Hits	425	Shared Neighborhood Hits	253
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ASPP1_HUMAN
NC score	0.551264 (rank : 220)	θ value	0.00869519 (rank : 265)
Query Neighborhood Hits	455	Target Neighborhood Hits	956	Shared Neighborhood Hits	283
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ILK2_HUMAN
NC score	0.546597 (rank : 221)	θ value	5.62301e-10 (rank : 158)
Query Neighborhood Hits	455	Target Neighborhood Hits	848	Shared Neighborhood Hits	286
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

GLSL_HUMAN
NC score	0.546048 (rank : 222)	θ value	0.000602161 (rank : 235)
Query Neighborhood Hits	455	Target Neighborhood Hits	211	Shared Neighborhood Hits	204
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

UACA_HUMAN
NC score	0.541420 (rank : 223)	θ value	8.65492e-19 (rank : 54)
Query Neighborhood Hits	455	Target Neighborhood Hits	1622	Shared Neighborhood Hits	301
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AN13B_MOUSE
NC score	0.538592 (rank : 224)	θ value	0.0193708 (rank : 278)
Query Neighborhood Hits	455	Target Neighborhood Hits	276	Shared Neighborhood Hits	254
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13C_HUMAN
NC score	0.538025 (rank : 225)	θ value	0.00228821 (rank : 243)
Query Neighborhood Hits	455	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13B_HUMAN
NC score	0.537987 (rank : 226)	θ value	0.0193708 (rank : 277)
Query Neighborhood Hits	455	Target Neighborhood Hits	265	Shared Neighborhood Hits	251
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ASPP1_MOUSE
NC score	0.536642 (rank : 227)	θ value	0.00869519 (rank : 266)
Query Neighborhood Hits	455	Target Neighborhood Hits	1244	Shared Neighborhood Hits	303
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

GLSL_MOUSE
NC score	0.533176 (rank : 228)	θ value	0.00228821 (rank : 246)
Query Neighborhood Hits	455	Target Neighborhood Hits	212	Shared Neighborhood Hits	205
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ILK1_HUMAN
NC score	0.528178 (rank : 229)	θ value	5.62301e-10 (rank : 157)
Query Neighborhood Hits	455	Target Neighborhood Hits	857	Shared Neighborhood Hits	286
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

AN13C_MOUSE
NC score	0.527191 (rank : 230)	θ value	0.00228821 (rank : 244)
Query Neighborhood Hits	455	Target Neighborhood Hits	242	Shared Neighborhood Hits	230
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ILK_MOUSE
NC score	0.526352 (rank : 231)	θ value	1.25267e-09 (rank : 163)
Query Neighborhood Hits	455	Target Neighborhood Hits	858	Shared Neighborhood Hits	284
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

TRPV5_MOUSE
NC score	0.521420 (rank : 232)	θ value	0.00665767 (rank : 261)
Query Neighborhood Hits	455	Target Neighborhood Hits	278	Shared Neighborhood Hits	245
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

GIT2_MOUSE
NC score	0.519844 (rank : 233)	θ value	0.00509761 (rank : 253)
Query Neighborhood Hits	455	Target Neighborhood Hits	323	Shared Neighborhood Hits	252
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

IASPP_MOUSE
NC score	0.519791 (rank : 234)	θ value	0.00102713 (rank : 238)
Query Neighborhood Hits	455	Target Neighborhood Hits	1024	Shared Neighborhood Hits	302
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

UACA_MOUSE
NC score	0.514138 (rank : 235)	θ value	4.74913e-17 (rank : 64)
Query Neighborhood Hits	455	Target Neighborhood Hits	1620	Shared Neighborhood Hits	299
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GLSK_HUMAN
NC score	0.507527 (rank : 236)	θ value	0.000121331 (rank : 224)
Query Neighborhood Hits	455	Target Neighborhood Hits	204	Shared Neighborhood Hits	191
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GIT1_MOUSE
NC score	0.499435 (rank : 237)	θ value	0.125558 (rank : 300)
Query Neighborhood Hits	455	Target Neighborhood Hits	341	Shared Neighborhood Hits	247
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.498096 (rank : 238)	θ value	0.125558 (rank : 299)
Query Neighborhood Hits	455	Target Neighborhood Hits	336	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

ANR26_MOUSE
NC score	0.494441 (rank : 239)	θ value	1.74796e-11 (rank : 138)
Query Neighborhood Hits	455	Target Neighborhood Hits	1554	Shared Neighborhood Hits	306
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TRPV6_HUMAN
NC score	0.493300 (rank : 240)	θ value	0.00228821 (rank : 247)
Query Neighborhood Hits	455	Target Neighborhood Hits	262	Shared Neighborhood Hits	224
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV5_HUMAN
NC score	0.491142 (rank : 241)	θ value	0.0961366 (rank : 298)
Query Neighborhood Hits	455	Target Neighborhood Hits	261	Shared Neighborhood Hits	223
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

NOTC4_MOUSE
NC score	0.485231 (rank : 242)	θ value	6.00763e-12 (rank : 130)
Query Neighborhood Hits	455	Target Neighborhood Hits	872	Shared Neighborhood Hits	286
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

GIT2_HUMAN
NC score	0.479328 (rank : 243)	θ value	0.0330416 (rank : 288)
Query Neighborhood Hits	455	Target Neighborhood Hits	381	Shared Neighborhood Hits	245
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

NOTC4_HUMAN
NC score	0.477985 (rank : 244)	θ value	1.33837e-11 (rank : 137)
Query Neighborhood Hits	455	Target Neighborhood Hits	905	Shared Neighborhood Hits	290
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANR26_HUMAN
NC score	0.475934 (rank : 245)	θ value	7.09661e-13 (rank : 113)
Query Neighborhood Hits	455	Target Neighborhood Hits	1614	Shared Neighborhood Hits	306
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN13A_HUMAN
NC score	0.475687 (rank : 246)	θ value	0.00665767 (rank : 256)
Query Neighborhood Hits	455	Target Neighborhood Hits	243	Shared Neighborhood Hits	221
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

DDFL1_MOUSE
NC score	0.474749 (rank : 247)	θ value	0.0113563 (rank : 274)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	249
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

TNI3K_HUMAN
NC score	0.469574 (rank : 248)	θ value	1.42661e-21 (rank : 41)
Query Neighborhood Hits	455	Target Neighborhood Hits	1084	Shared Neighborhood Hits	305
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
NC score	0.464048 (rank : 249)	θ value	1.42661e-21 (rank : 42)
Query Neighborhood Hits	455	Target Neighborhood Hits	1079	Shared Neighborhood Hits	303
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CT012_MOUSE
NC score	0.451139 (rank : 250)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	455	Target Neighborhood Hits	229	Shared Neighborhood Hits	176
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

AN13A_MOUSE
NC score	0.448929 (rank : 251)	θ value	0.163984 (rank : 304)
Query Neighborhood Hits	455	Target Neighborhood Hits	226	Shared Neighborhood Hits	215
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

NOTC3_MOUSE
NC score	0.442234 (rank : 252)	θ value	3.18553e-13 (rank : 110)
Query Neighborhood Hits	455	Target Neighborhood Hits	975	Shared Neighborhood Hits	290
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.440507 (rank : 253)	θ value	1.058e-16 (rank : 68)
Query Neighborhood Hits	455	Target Neighborhood Hits	906	Shared Neighborhood Hits	285
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
NC score	0.439965 (rank : 254)	θ value	3.18553e-13 (rank : 109)
Query Neighborhood Hits	455	Target Neighborhood Hits	1062	Shared Neighborhood Hits	295
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.437792 (rank : 255)	θ value	2.88119e-14 (rank : 88)
Query Neighborhood Hits	455	Target Neighborhood Hits	1113	Shared Neighborhood Hits	302
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
NC score	0.435000 (rank : 256)	θ value	6.41864e-14 (rank : 92)
Query Neighborhood Hits	455	Target Neighborhood Hits	1069	Shared Neighborhood Hits	295
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DAPK1_MOUSE
NC score	0.427798 (rank : 257)	θ value	1.57365e-28 (rank : 19)
Query Neighborhood Hits	455	Target Neighborhood Hits	1138	Shared Neighborhood Hits	306
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TEX14_MOUSE
NC score	0.422782 (rank : 258)	θ value	1.53129e-07 (rank : 189)
Query Neighborhood Hits	455	Target Neighborhood Hits	1333	Shared Neighborhood Hits	283
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_HUMAN
NC score	0.418983 (rank : 259)	θ value	1.87187e-05 (rank : 214)
Query Neighborhood Hits	455	Target Neighborhood Hits	1103	Shared Neighborhood Hits	267
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DAPK1_HUMAN
NC score	0.418727 (rank : 260)	θ value	4.14116e-29 (rank : 18)
Query Neighborhood Hits	455	Target Neighborhood Hits	1130	Shared Neighborhood Hits	303
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

CT012_HUMAN
NC score	0.409135 (rank : 261)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	164
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DDEF2_HUMAN
NC score	0.400488 (rank : 262)	θ value	0.0113563 (rank : 272)
Query Neighborhood Hits	455	Target Neighborhood Hits	599	Shared Neighborhood Hits	247
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.397817 (rank : 263)	θ value	0.0113563 (rank : 273)
Query Neighborhood Hits	455	Target Neighborhood Hits	625	Shared Neighborhood Hits	249
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DGKZ_HUMAN
NC score	0.391492 (rank : 264)	θ value	0.00298849 (rank : 248)
Query Neighborhood Hits	455	Target Neighborhood Hits	551	Shared Neighborhood Hits	220
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DDFL1_HUMAN
NC score	0.381161 (rank : 265)	θ value	0.0252991 (rank : 284)
Query Neighborhood Hits	455	Target Neighborhood Hits	353	Shared Neighborhood Hits	235
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

NOTC1_MOUSE
NC score	0.377403 (rank : 266)	θ value	3.18553e-13 (rank : 108)
Query Neighborhood Hits	455	Target Neighborhood Hits	916	Shared Neighborhood Hits	264
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DGKZ_MOUSE
NC score	0.371719 (rank : 267)	θ value	0.00665767 (rank : 259)
Query Neighborhood Hits	455	Target Neighborhood Hits	542	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG1_MOUSE
NC score	0.371322 (rank : 268)	θ value	0.0563607 (rank : 295)
Query Neighborhood Hits	455	Target Neighborhood Hits	531	Shared Neighborhood Hits	245
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.369222 (rank : 269)	θ value	0.0563607 (rank : 294)
Query Neighborhood Hits	455	Target Neighborhood Hits	544	Shared Neighborhood Hits	246
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_HUMAN
NC score	0.369154 (rank : 270)	θ value	0.00869519 (rank : 267)
Query Neighborhood Hits	455	Target Neighborhood Hits	471	Shared Neighborhood Hits	252
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
NC score	0.367647 (rank : 271)	θ value	0.00228821 (rank : 245)
Query Neighborhood Hits	455	Target Neighborhood Hits	463	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

ANKZ1_MOUSE
NC score	0.363336 (rank : 272)	θ value	0.00869519 (rank : 264)
Query Neighborhood Hits	455	Target Neighborhood Hits	208	Shared Neighborhood Hits	152
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

DGKI_HUMAN
NC score	0.358996 (rank : 273)	θ value	0.0431538 (rank : 292)
Query Neighborhood Hits	455	Target Neighborhood Hits	609	Shared Neighborhood Hits	222
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

ANKZ1_HUMAN
NC score	0.346747 (rank : 274)	θ value	0.0148317 (rank : 275)
Query Neighborhood Hits	455	Target Neighborhood Hits	236	Shared Neighborhood Hits	157
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ABTB1_MOUSE
NC score	0.341525 (rank : 275)	θ value	0.00020696 (rank : 227)
Query Neighborhood Hits	455	Target Neighborhood Hits	349	Shared Neighborhood Hits	176
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

CENG3_MOUSE
NC score	0.340870 (rank : 276)	θ value	0.000158464 (rank : 226)
Query Neighborhood Hits	455	Target Neighborhood Hits	467	Shared Neighborhood Hits	229
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.340566 (rank : 277)	θ value	0.000158464 (rank : 225)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

IKBL_HUMAN
NC score	0.327839 (rank : 278)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
NC score	0.320840 (rank : 279)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	455	Target Neighborhood Hits	196	Shared Neighborhood Hits	140
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CLR59_HUMAN
NC score	0.309483 (rank : 280)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	455	Target Neighborhood Hits	163	Shared Neighborhood Hits	141
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

DDEF1_MOUSE
NC score	0.301940 (rank : 281)	θ value	0.163984 (rank : 305)
Query Neighborhood Hits	455	Target Neighborhood Hits	592	Shared Neighborhood Hits	205
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

ABTB1_HUMAN
NC score	0.298851 (rank : 282)	θ value	0.000461057 (rank : 233)
Query Neighborhood Hits	455	Target Neighborhood Hits	325	Shared Neighborhood Hits	161
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ANKR9_MOUSE
NC score	0.279279 (rank : 283)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	455	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BAT4_MOUSE
NC score	0.271454 (rank : 284)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	455	Target Neighborhood Hits	171	Shared Neighborhood Hits	121
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

TRPV1_MOUSE
NC score	0.262401 (rank : 285)	θ value	0.00665767 (rank : 260)
Query Neighborhood Hits	455	Target Neighborhood Hits	189	Shared Neighborhood Hits	153
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

RSNL2_HUMAN
NC score	0.260572 (rank : 286)	θ value	0.0252991 (rank : 286)
Query Neighborhood Hits	455	Target Neighborhood Hits	136	Shared Neighborhood Hits	114
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV3_MOUSE
NC score	0.260189 (rank : 287)	θ value	0.0330416 (rank : 290)
Query Neighborhood Hits	455	Target Neighborhood Hits	188	Shared Neighborhood Hits	129
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
NC score	0.256336 (rank : 288)	θ value	0.163984 (rank : 307)
Query Neighborhood Hits	455	Target Neighborhood Hits	198	Shared Neighborhood Hits	142
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

CMTA1_HUMAN
NC score	0.253876 (rank : 289)	θ value	0.000786445 (rank : 236)
Query Neighborhood Hits	455	Target Neighborhood Hits	217	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

TRPV1_HUMAN
NC score	0.245269 (rank : 290)	θ value	0.0193708 (rank : 282)
Query Neighborhood Hits	455	Target Neighborhood Hits	184	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

BAT4_HUMAN
NC score	0.241808 (rank : 291)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	455	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

ANKR9_HUMAN
NC score	0.228509 (rank : 292)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	455	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

RSNL2_MOUSE
NC score	0.224636 (rank : 293)	θ value	0.0252991 (rank : 287)
Query Neighborhood Hits	455	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV2_HUMAN
NC score	0.224430 (rank : 294)	θ value	1.38821 (rank : 351)
Query Neighborhood Hits	455	Target Neighborhood Hits	130	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CMTA2_HUMAN
NC score	0.214935 (rank : 295)	θ value	0.000270298 (rank : 229)
Query Neighborhood Hits	455	Target Neighborhood Hits	199	Shared Neighborhood Hits	98
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
NC score	0.203696 (rank : 296)	θ value	0.00035302 (rank : 231)
Query Neighborhood Hits	455	Target Neighborhood Hits	216	Shared Neighborhood Hits	85
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPV2_MOUSE
NC score	0.172244 (rank : 297)	θ value	8.99809 (rank : 455)
Query Neighborhood Hits	455	Target Neighborhood Hits	111	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

ANKF1_HUMAN
NC score	0.142129 (rank : 298)	θ value	5.27518 (rank : 409)
Query Neighborhood Hits	455	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

TRPV4_HUMAN
NC score	0.132322 (rank : 299)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	455	Target Neighborhood Hits	150	Shared Neighborhood Hits	80
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CU081_HUMAN
NC score	0.125305 (rank : 300)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	455	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

TRPV4_MOUSE
NC score	0.121731 (rank : 301)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	455	Target Neighborhood Hits	117	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPC6_HUMAN
NC score	0.112807 (rank : 302)	θ value	0.21417 (rank : 315)
Query Neighborhood Hits	455	Target Neighborhood Hits	171	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

LRRK1_MOUSE
NC score	0.100929 (rank : 303)	θ value	0.00298849 (rank : 249)
Query Neighborhood Hits	455	Target Neighborhood Hits	1267	Shared Neighborhood Hits	135
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

TRPC3_HUMAN
NC score	0.089068 (rank : 304)	θ value	1.38821 (rank : 349)
Query Neighborhood Hits	455	Target Neighborhood Hits	137	Shared Neighborhood Hits	79
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

SRRM2_HUMAN
NC score	0.085014 (rank : 305)	θ value	0.000786445 (rank : 237)
Query Neighborhood Hits	455	Target Neighborhood Hits	1296	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRPC6_MOUSE
NC score	0.082180 (rank : 306)	θ value	1.38821 (rank : 350)
Query Neighborhood Hits	455	Target Neighborhood Hits	171	Shared Neighborhood Hits	87
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC3_MOUSE
NC score	0.077756 (rank : 307)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	455	Target Neighborhood Hits	131	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

LRRK1_HUMAN
NC score	0.073385 (rank : 308)	θ value	1.06291 (rank : 334)
Query Neighborhood Hits	455	Target Neighborhood Hits	1237	Shared Neighborhood Hits	108
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

SRRM2_MOUSE
NC score	0.072325 (rank : 309)	θ value	0.00134147 (rank : 241)
Query Neighborhood Hits	455	Target Neighborhood Hits	1470	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TRPC7_MOUSE
NC score	0.071494 (rank : 310)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	455	Target Neighborhood Hits	114	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.070931 (rank : 311)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	455	Target Neighborhood Hits	123	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

SRRM1_MOUSE
NC score	0.070337 (rank : 312)	θ value	0.62314 (rank : 330)
Query Neighborhood Hits	455	Target Neighborhood Hits	966	Shared Neighborhood Hits	91
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TRPC5_MOUSE
NC score	0.065402 (rank : 313)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	455	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TARA_HUMAN
NC score	0.064104 (rank : 314)	θ value	3.0926 (rank : 389)
Query Neighborhood Hits	455	Target Neighborhood Hits	1626	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRPC5_HUMAN
NC score	0.063971 (rank : 315)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	455	Target Neighborhood Hits	122	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

PRP1_HUMAN
NC score	0.063069 (rank : 316)	θ value	0.0193708 (rank : 280)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	48
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

TRPC4_MOUSE
NC score	0.062039 (rank : 317)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	455	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
NC score	0.061928 (rank : 318)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	455	Target Neighborhood Hits	140	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

FILA_HUMAN
NC score	0.061683 (rank : 319)	θ value	0.000121331 (rank : 223)
Query Neighborhood Hits	455	Target Neighborhood Hits	685	Shared Neighborhood Hits	57
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

SRRM1_HUMAN
NC score	0.060908 (rank : 320)	θ value	0.365318 (rank : 322)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

FADD_MOUSE
NC score	0.060654 (rank : 321)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	455	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

BAT2_HUMAN
NC score	0.058748 (rank : 322)	θ value	0.21417 (rank : 309)
Query Neighborhood Hits	455	Target Neighborhood Hits	931	Shared Neighborhood Hits	91
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
NC score	0.057873 (rank : 323)	θ value	0.00665767 (rank : 258)
Query Neighborhood Hits	455	Target Neighborhood Hits	947	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SSB4_HUMAN
NC score	0.055238 (rank : 324)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	455	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

FADD_HUMAN
NC score	0.054845 (rank : 325)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	455	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

SPSB2_MOUSE
NC score	0.054401 (rank : 326)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	455	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

REL_MOUSE
NC score	0.053993 (rank : 327)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	455	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

TRDN_HUMAN
NC score	0.052775 (rank : 328)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	455	Target Neighborhood Hits	542	Shared Neighborhood Hits	36
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

REL_HUMAN
NC score	0.052148 (rank : 329)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	455	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

TF65_HUMAN
NC score	0.051778 (rank : 330)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	455	Target Neighborhood Hits	115	Shared Neighborhood Hits	17
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

SMAP1_MOUSE
NC score	0.051288 (rank : 331)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	455	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

RELB_HUMAN
NC score	0.051190 (rank : 332)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	455	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

RELB_MOUSE
NC score	0.051190 (rank : 333)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	455	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

TF65_MOUSE
NC score	0.051081 (rank : 334)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	455	Target Neighborhood Hits	66	Shared Neighborhood Hits	7
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

SSB4_MOUSE
NC score	0.050716 (rank : 335)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R5B6, Q8BJI9, Q8VHS8	Gene names	Spsb4, Ssb4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

LCE1B_HUMAN
NC score	0.050137 (rank : 336)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	455	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

SET1A_HUMAN
NC score	0.049460 (rank : 337)	θ value	6.88961 (rank : 436)
Query Neighborhood Hits	455	Target Neighborhood Hits	690	Shared Neighborhood Hits	57
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ACINU_MOUSE
NC score	0.048841 (rank : 338)	θ value	0.00869519 (rank : 262)
Query Neighborhood Hits	455	Target Neighborhood Hits	712	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NACAM_MOUSE
NC score	0.047720 (rank : 339)	θ value	4.03905 (rank : 400)
Query Neighborhood Hits	455	Target Neighborhood Hits	1866	Shared Neighborhood Hits	130
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CMGA_HUMAN
NC score	0.047087 (rank : 340)	θ value	0.0193708 (rank : 279)
Query Neighborhood Hits	455	Target Neighborhood Hits	238	Shared Neighborhood Hits	21
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

HORN_MOUSE
NC score	0.047051 (rank : 341)	θ value	0.00134147 (rank : 240)
Query Neighborhood Hits	455	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

NFH_MOUSE
NC score	0.046393 (rank : 342)	θ value	1.06291 (rank : 335)
Query Neighborhood Hits	455	Target Neighborhood Hits	2247	Shared Neighborhood Hits	152
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRB4S_HUMAN
NC score	0.045565 (rank : 343)	θ value	2.36792 (rank : 368)
Query Neighborhood Hits	455	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SFRS4_HUMAN
NC score	0.043637 (rank : 344)	θ value	0.00869519 (rank : 268)
Query Neighborhood Hits	455	Target Neighborhood Hits	384	Shared Neighborhood Hits	30
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SFR11_HUMAN
NC score	0.043634 (rank : 345)	θ value	5.27518 (rank : 418)
Query Neighborhood Hits	455	Target Neighborhood Hits	246	Shared Neighborhood Hits	26
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

XPC_MOUSE
NC score	0.042845 (rank : 346)	θ value	0.00175202 (rank : 242)
Query Neighborhood Hits	455	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

PCLO_HUMAN
NC score	0.042154 (rank : 347)	θ value	4.03905 (rank : 401)
Query Neighborhood Hits	455	Target Neighborhood Hits	2046	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRB3_HUMAN
NC score	0.041842 (rank : 348)	θ value	0.279714 (rank : 317)
Query Neighborhood Hits	455	Target Neighborhood Hits	318	Shared Neighborhood Hits	42
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

RRBP1_MOUSE
NC score	0.041519 (rank : 349)	θ value	0.163984 (rank : 306)
Query Neighborhood Hits	455	Target Neighborhood Hits	1650	Shared Neighborhood Hits	100
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ACINU_HUMAN
NC score	0.040933 (rank : 350)	θ value	4.03905 (rank : 392)
Query Neighborhood Hits	455	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MUC1_MOUSE
NC score	0.040591 (rank : 351)	θ value	0.0330416 (rank : 289)
Query Neighborhood Hits	455	Target Neighborhood Hits	388	Shared Neighborhood Hits	35
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

RP1L1_HUMAN
NC score	0.039917 (rank : 352)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	455	Target Neighborhood Hits	1072	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MAP1B_MOUSE
NC score	0.038168 (rank : 353)	θ value	6.88961 (rank : 430)
Query Neighborhood Hits	455	Target Neighborhood Hits	977	Shared Neighborhood Hits	71
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

AFF1_HUMAN
NC score	0.037670 (rank : 354)	θ value	5.27518 (rank : 408)
Query Neighborhood Hits	455	Target Neighborhood Hits	506	Shared Neighborhood Hits	62
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF4_HUMAN
NC score	0.037395 (rank : 355)	θ value	4.03905 (rank : 393)
Query Neighborhood Hits	455	Target Neighborhood Hits	611	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ZAN_MOUSE
NC score	0.037019 (rank : 356)	θ value	6.88961 (rank : 438)
Query Neighborhood Hits	455	Target Neighborhood Hits	808	Shared Neighborhood Hits	20
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FYB_HUMAN
NC score	0.036879 (rank : 357)	θ value	0.21417 (rank : 311)
Query Neighborhood Hits	455	Target Neighborhood Hits	379	Shared Neighborhood Hits	51
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

CJ047_HUMAN
NC score	0.035630 (rank : 358)	θ value	0.0431538 (rank : 291)
Query Neighborhood Hits	455	Target Neighborhood Hits	164	Shared Neighborhood Hits	23
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

ENL_HUMAN
NC score	0.035437 (rank : 359)	θ value	1.81305 (rank : 355)
Query Neighborhood Hits	455	Target Neighborhood Hits	305	Shared Neighborhood Hits	37
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

PCLO_MOUSE
NC score	0.034805 (rank : 360)	θ value	5.27518 (rank : 417)
Query Neighborhood Hits	455	Target Neighborhood Hits	2275	Shared Neighborhood Hits	133
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RGS3_MOUSE
NC score	0.033493 (rank : 361)	θ value	2.36792 (rank : 371)
Query Neighborhood Hits	455	Target Neighborhood Hits	1621	Shared Neighborhood Hits	118
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NIN_MOUSE
NC score	0.033122 (rank : 362)	θ value	6.88961 (rank : 433)
Query Neighborhood Hits	455	Target Neighborhood Hits	1376	Shared Neighborhood Hits	50
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

MUCDL_HUMAN
NC score	0.032996 (rank : 363)	θ value	4.03905 (rank : 399)
Query Neighborhood Hits	455	Target Neighborhood Hits	777	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

HORN_HUMAN
NC score	0.032114 (rank : 364)	θ value	6.88961 (rank : 426)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

SFRS4_MOUSE
NC score	0.032055 (rank : 365)	θ value	0.0193708 (rank : 281)
Query Neighborhood Hits	455	Target Neighborhood Hits	406	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

NCOR2_HUMAN
NC score	0.032049 (rank : 366)	θ value	1.81305 (rank : 360)
Query Neighborhood Hits	455	Target Neighborhood Hits	870	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

REPS1_MOUSE
NC score	0.031829 (rank : 367)	θ value	0.365318 (rank : 321)
Query Neighborhood Hits	455	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

NFH_HUMAN
NC score	0.030223 (rank : 368)	θ value	1.38821 (rank : 345)
Query Neighborhood Hits	455	Target Neighborhood Hits	1242	Shared Neighborhood Hits	84
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

K1683_HUMAN
NC score	0.029530 (rank : 369)	θ value	1.81305 (rank : 357)
Query Neighborhood Hits	455	Target Neighborhood Hits	240	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

PKHA4_HUMAN
NC score	0.028534 (rank : 370)	θ value	0.47712 (rank : 325)
Query Neighborhood Hits	455	Target Neighborhood Hits	283	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

STRAD_MOUSE
NC score	0.028225 (rank : 371)	θ value	2.36792 (rank : 373)
Query Neighborhood Hits	455	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	Q60924	Gene names	Stra13
Domain Architecture	No domain graphic available
Description	Retinoic acid-inducible E3 protein (Hematopoietic-specific protein E3).

DSPP_HUMAN
NC score	0.027504 (rank : 372)	θ value	0.21417 (rank : 310)
Query Neighborhood Hits	455	Target Neighborhood Hits	645	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DOS_HUMAN
NC score	0.027069 (rank : 373)	θ value	0.365318 (rank : 320)
Query Neighborhood Hits	455	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

SYN3_MOUSE
NC score	0.026936 (rank : 374)	θ value	0.125558 (rank : 303)
Query Neighborhood Hits	455	Target Neighborhood Hits	200	Shared Neighborhood Hits	33
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

ASPM_MOUSE
NC score	0.026323 (rank : 375)	θ value	0.21417 (rank : 308)
Query Neighborhood Hits	455	Target Neighborhood Hits	150	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

RIMB1_MOUSE
NC score	0.025344 (rank : 376)	θ value	1.38821 (rank : 348)
Query Neighborhood Hits	455	Target Neighborhood Hits	1376	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PPRB_MOUSE
NC score	0.024278 (rank : 377)	θ value	3.0926 (rank : 387)
Query Neighborhood Hits	455	Target Neighborhood Hits	354	Shared Neighborhood Hits	37
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

CUTL1_HUMAN
NC score	0.024057 (rank : 378)	θ value	4.03905 (rank : 394)
Query Neighborhood Hits	455	Target Neighborhood Hits	1574	Shared Neighborhood Hits	70
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DOT1L_HUMAN
NC score	0.023466 (rank : 379)	θ value	6.88961 (rank : 424)
Query Neighborhood Hits	455	Target Neighborhood Hits	660	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

TARSH_HUMAN
NC score	0.023134 (rank : 380)	θ value	8.99809 (rank : 454)
Query Neighborhood Hits	455	Target Neighborhood Hits	768	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PPRB_HUMAN
NC score	0.022823 (rank : 381)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	455	Target Neighborhood Hits	311	Shared Neighborhood Hits	30
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

REPS1_HUMAN
NC score	0.022462 (rank : 382)	θ value	0.21417 (rank : 313)
Query Neighborhood Hits	455	Target Neighborhood Hits	205	Shared Neighborhood Hits	17
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SFPQ_MOUSE
NC score	0.022191 (rank : 383)	θ value	1.06291 (rank : 338)
Query Neighborhood Hits	455	Target Neighborhood Hits	958	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SRCA_HUMAN
NC score	0.022049 (rank : 384)	θ value	0.279714 (rank : 318)
Query Neighborhood Hits	455	Target Neighborhood Hits	380	Shared Neighborhood Hits	41
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TCAL5_HUMAN
NC score	0.020722 (rank : 385)	θ value	2.36792 (rank : 374)
Query Neighborhood Hits	455	Target Neighborhood Hits	806	Shared Neighborhood Hits	62
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

PP1RA_MOUSE
NC score	0.020590 (rank : 386)	θ value	0.62314 (rank : 329)
Query Neighborhood Hits	455	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

MYLK2_HUMAN
NC score	0.020584 (rank : 387)	θ value	0.00390308 (rank : 251)
Query Neighborhood Hits	455	Target Neighborhood Hits	920	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

SFPQ_HUMAN
NC score	0.020422 (rank : 388)	θ value	2.36792 (rank : 372)
Query Neighborhood Hits	455	Target Neighborhood Hits	986	Shared Neighborhood Hits	63
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SYN3_HUMAN
NC score	0.020417 (rank : 389)	θ value	1.81305 (rank : 362)
Query Neighborhood Hits	455	Target Neighborhood Hits	203	Shared Neighborhood Hits	31
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

P_HUMAN
NC score	0.020256 (rank : 390)	θ value	0.125558 (rank : 301)
Query Neighborhood Hits	455	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q04671, Q15211, Q15212, Q96EN1, Q9UMI5	Gene names	OCA2, P
Domain Architecture
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog).

GON4L_MOUSE
NC score	0.020192 (rank : 391)	θ value	6.88961 (rank : 425)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

CD2_HUMAN
NC score	0.020070 (rank : 392)	θ value	5.27518 (rank : 410)
Query Neighborhood Hits	455	Target Neighborhood Hits	504	Shared Neighborhood Hits	41
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

ITF2_MOUSE
NC score	0.019964 (rank : 393)	θ value	4.03905 (rank : 396)
Query Neighborhood Hits	455	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

ITF2_HUMAN
NC score	0.019905 (rank : 394)	θ value	2.36792 (rank : 366)
Query Neighborhood Hits	455	Target Neighborhood Hits	168	Shared Neighborhood Hits	17
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

RGS3_HUMAN
NC score	0.019830 (rank : 395)	θ value	2.36792 (rank : 370)
Query Neighborhood Hits	455	Target Neighborhood Hits	1375	Shared Neighborhood Hits	92
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RBM15_HUMAN
NC score	0.019681 (rank : 396)	θ value	1.06291 (rank : 336)
Query Neighborhood Hits	455	Target Neighborhood Hits	309	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

CABYR_MOUSE
NC score	0.019620 (rank : 397)	θ value	1.81305 (rank : 352)
Query Neighborhood Hits	455	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

ADRM1_HUMAN
NC score	0.019606 (rank : 398)	θ value	6.88961 (rank : 420)
Query Neighborhood Hits	455	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

ASPX_HUMAN
NC score	0.019578 (rank : 399)	θ value	2.36792 (rank : 364)
Query Neighborhood Hits	455	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

CCNK_MOUSE
NC score	0.019105 (rank : 400)	θ value	1.38821 (rank : 339)
Query Neighborhood Hits	455	Target Neighborhood Hits	350	Shared Neighborhood Hits	29
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

MARK2_HUMAN
NC score	0.019094 (rank : 401)	θ value	0.62314 (rank : 327)
Query Neighborhood Hits	455	Target Neighborhood Hits	1056	Shared Neighborhood Hits	58
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

PKHA5_HUMAN
NC score	0.019073 (rank : 402)	θ value	4.03905 (rank : 402)
Query Neighborhood Hits	455	Target Neighborhood Hits	455	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PRP4B_MOUSE
NC score	0.018541 (rank : 403)	θ value	0.0961366 (rank : 297)
Query Neighborhood Hits	455	Target Neighborhood Hits	1040	Shared Neighborhood Hits	49
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

K1914_HUMAN
NC score	0.018505 (rank : 404)	θ value	1.81305 (rank : 358)
Query Neighborhood Hits	455	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

APXL_HUMAN
NC score	0.018002 (rank : 405)	θ value	6.88961 (rank : 422)
Query Neighborhood Hits	455	Target Neighborhood Hits	553	Shared Neighborhood Hits	49
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

RNF25_HUMAN
NC score	0.017937 (rank : 406)	θ value	1.81305 (rank : 361)
Query Neighborhood Hits	455	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RECQ5_HUMAN
NC score	0.017810 (rank : 407)	θ value	0.21417 (rank : 312)
Query Neighborhood Hits	455	Target Neighborhood Hits	390	Shared Neighborhood Hits	46
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

CLIC6_HUMAN
NC score	0.017551 (rank : 408)	θ value	0.0961366 (rank : 296)
Query Neighborhood Hits	455	Target Neighborhood Hits	289	Shared Neighborhood Hits	30
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

HTF4_HUMAN
NC score	0.017336 (rank : 409)	θ value	1.38821 (rank : 343)
Query Neighborhood Hits	455	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

CO039_HUMAN
NC score	0.017323 (rank : 410)	θ value	5.27518 (rank : 411)
Query Neighborhood Hits	455	Target Neighborhood Hits	264	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

BPTF_HUMAN
NC score	0.017321 (rank : 411)	θ value	3.0926 (rank : 376)
Query Neighborhood Hits	455	Target Neighborhood Hits	786	Shared Neighborhood Hits	49
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MUCDL_MOUSE
NC score	0.016618 (rank : 412)	θ value	0.62314 (rank : 328)
Query Neighborhood Hits	455	Target Neighborhood Hits	461	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CD2L5_HUMAN
NC score	0.016514 (rank : 413)	θ value	0.00134147 (rank : 239)
Query Neighborhood Hits	455	Target Neighborhood Hits	987	Shared Neighborhood Hits	39
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

DHDDS_MOUSE
NC score	0.015826 (rank : 414)	θ value	4.03905 (rank : 395)
Query Neighborhood Hits	455	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KU1, Q3UF13, Q8BZ16, Q8BZK8	Gene names	Dhdds
Domain Architecture
Description	Dehydrodolichyl diphosphate synthase (EC 2.5.1.-) (Dedol-PP synthase).

CD2L5_MOUSE
NC score	0.015714 (rank : 415)	θ value	0.0252991 (rank : 283)
Query Neighborhood Hits	455	Target Neighborhood Hits	1011	Shared Neighborhood Hits	45
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

HTF4_MOUSE
NC score	0.015568 (rank : 416)	θ value	1.38821 (rank : 344)
Query Neighborhood Hits	455	Target Neighborhood Hits	153	Shared Neighborhood Hits	12
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

PP1RA_HUMAN
NC score	0.015377 (rank : 417)	θ value	3.0926 (rank : 386)
Query Neighborhood Hits	455	Target Neighborhood Hits	180	Shared Neighborhood Hits	22
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

NKTR_MOUSE
NC score	0.015325 (rank : 418)	θ value	1.38821 (rank : 346)
Query Neighborhood Hits	455	Target Neighborhood Hits	417	Shared Neighborhood Hits	35
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

SPEG_HUMAN
NC score	0.014957 (rank : 419)	θ value	0.125558 (rank : 302)
Query Neighborhood Hits	455	Target Neighborhood Hits	1762	Shared Neighborhood Hits	89
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

YBOX2_MOUSE
NC score	0.014708 (rank : 420)	θ value	0.62314 (rank : 331)
Query Neighborhood Hits	455	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

GGN_HUMAN
NC score	0.014231 (rank : 421)	θ value	3.0926 (rank : 382)
Query Neighborhood Hits	455	Target Neighborhood Hits	269	Shared Neighborhood Hits	27
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

JPH2_MOUSE
NC score	0.014207 (rank : 422)	θ value	4.03905 (rank : 397)
Query Neighborhood Hits	455	Target Neighborhood Hits	279	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

DBNL_MOUSE
NC score	0.014124 (rank : 423)	θ value	1.81305 (rank : 354)
Query Neighborhood Hits	455	Target Neighborhood Hits	306	Shared Neighborhood Hits	21
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

ELOA3_HUMAN
NC score	0.013801 (rank : 424)	θ value	3.0926 (rank : 381)
Query Neighborhood Hits	455	Target Neighborhood Hits	98	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

CO1A1_HUMAN
NC score	0.013647 (rank : 425)	θ value	1.38821 (rank : 340)
Query Neighborhood Hits	455	Target Neighborhood Hits	475	Shared Neighborhood Hits	43
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
NC score	0.013531 (rank : 426)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	455	Target Neighborhood Hits	452	Shared Neighborhood Hits	43
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

AL2S4_HUMAN
NC score	0.013327 (rank : 427)	θ value	6.88961 (rank : 421)
Query Neighborhood Hits	455	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q96Q45, Q53TS9, Q53TT2, Q7Z3B6, Q8IZ18, Q8NBF8, Q96CY1	Gene names	ALS2CR4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein.

CO3A1_MOUSE
NC score	0.013256 (rank : 428)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	455	Target Neighborhood Hits	466	Shared Neighborhood Hits	40
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

AATK_MOUSE
NC score	0.013183 (rank : 429)	θ value	5.27518 (rank : 407)
Query Neighborhood Hits	455	Target Neighborhood Hits	942	Shared Neighborhood Hits	48
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

OBSCN_HUMAN
NC score	0.013132 (rank : 430)	θ value	0.279714 (rank : 316)
Query Neighborhood Hits	455	Target Neighborhood Hits	1931	Shared Neighborhood Hits	91
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

CO5A1_HUMAN
NC score	0.012346 (rank : 431)	θ value	0.62314 (rank : 326)
Query Neighborhood Hits	455	Target Neighborhood Hits	434	Shared Neighborhood Hits	41
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CM003_HUMAN
NC score	0.012061 (rank : 432)	θ value	3.0926 (rank : 380)
Query Neighborhood Hits	455	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IX90, Q5VZV5, Q86WR2, Q8NBG1, Q96D22	Gene names	C13orf3, RAMA1
Domain Architecture	No domain graphic available
Description	Protein C13orf3.

PAK6_HUMAN
NC score	0.011983 (rank : 433)	θ value	3.0926 (rank : 385)
Query Neighborhood Hits	455	Target Neighborhood Hits	915	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

RNF25_MOUSE
NC score	0.011523 (rank : 434)	θ value	4.03905 (rank : 403)
Query Neighborhood Hits	455	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

IF39_MOUSE
NC score	0.011342 (rank : 435)	θ value	5.27518 (rank : 413)
Query Neighborhood Hits	455	Target Neighborhood Hits	206	Shared Neighborhood Hits	18
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

DNM3A_MOUSE
NC score	0.011242 (rank : 436)	θ value	1.38821 (rank : 342)
Query Neighborhood Hits	455	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

SPTN5_HUMAN
NC score	0.010980 (rank : 437)	θ value	5.27518 (rank : 419)
Query Neighborhood Hits	455	Target Neighborhood Hits	674	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

CD5R2_MOUSE
NC score	0.010708 (rank : 438)	θ value	1.81305 (rank : 353)
Query Neighborhood Hits	455	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	O35926, O35277	Gene names	Cdk5r2, Nck5ai
Domain Architecture
Description	Cyclin-dependent kinase 5 activator 2 precursor (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (P39) (P39I).

POL2_MOUSE
NC score	0.010560 (rank : 439)	θ value	1.38821 (rank : 347)
Query Neighborhood Hits	455	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P11369, Q60713, Q61787	Gene names	Pol
Domain Architecture
Description	Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element- 1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease].

IQGA1_MOUSE
NC score	0.010299 (rank : 440)	θ value	5.27518 (rank : 414)
Query Neighborhood Hits	455	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

CK035_HUMAN
NC score	0.010130 (rank : 441)	θ value	3.0926 (rank : 379)
Query Neighborhood Hits	455	Target Neighborhood Hits	149	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXW0	Gene names	C11orf35
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35.

MYO3A_HUMAN
NC score	0.009750 (rank : 442)	θ value	2.36792 (rank : 367)
Query Neighborhood Hits	455	Target Neighborhood Hits	1033	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

JHD2C_MOUSE
NC score	0.009664 (rank : 443)	θ value	6.88961 (rank : 427)
Query Neighborhood Hits	455	Target Neighborhood Hits	297	Shared Neighborhood Hits	30
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

RP3A_MOUSE
NC score	0.009634 (rank : 444)	θ value	0.21417 (rank : 314)
Query Neighborhood Hits	455	Target Neighborhood Hits	510	Shared Neighborhood Hits	54
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

HCN2_HUMAN
NC score	0.008800 (rank : 445)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	455	Target Neighborhood Hits	369	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

KCNQ5_HUMAN
NC score	0.008753 (rank : 446)	θ value	3.0926 (rank : 384)
Query Neighborhood Hits	455	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

UT14B_MOUSE
NC score	0.008494 (rank : 447)	θ value	4.03905 (rank : 406)
Query Neighborhood Hits	455	Target Neighborhood Hits	226	Shared Neighborhood Hits	14
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

MYO9B_HUMAN
NC score	0.008242 (rank : 448)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	455	Target Neighborhood Hits	641	Shared Neighborhood Hits	64
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CD2L6_MOUSE
NC score	0.008085 (rank : 449)	θ value	6.88961 (rank : 423)
Query Neighborhood Hits	455	Target Neighborhood Hits	851	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

KCNQ2_HUMAN
NC score	0.007881 (rank : 450)	θ value	1.81305 (rank : 359)
Query Neighborhood Hits	455	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

CASZ1_HUMAN
NC score	0.007843 (rank : 451)	θ value	0.47712 (rank : 323)
Query Neighborhood Hits	455	Target Neighborhood Hits	473	Shared Neighborhood Hits	15
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

SEPT7_HUMAN
NC score	0.007608 (rank : 452)	θ value	6.88961 (rank : 435)
Query Neighborhood Hits	455	Target Neighborhood Hits	385	Shared Neighborhood Hits	17
SwissProt Accessions	Q16181, Q6NX50	Gene names	SEPT7, CDC10
Domain Architecture
Description	Septin-7 (CDC10 protein homolog).

MYO3A_MOUSE
NC score	0.007213 (rank : 453)	θ value	6.88961 (rank : 431)
Query Neighborhood Hits	455	Target Neighborhood Hits	902	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3H5	Gene names	Myo3a
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

RNF12_HUMAN
NC score	0.007133 (rank : 454)	θ value	3.0926 (rank : 388)
Query Neighborhood Hits	455	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

HDC_HUMAN
NC score	0.006762 (rank : 455)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	455	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBI9	Gene names	HECA, HDC
Domain Architecture	No domain graphic available
Description	Headcase protein homolog (hHDC).

TTBK1_HUMAN
NC score	0.005819 (rank : 456)	θ value	3.0926 (rank : 390)
Query Neighborhood Hits	455	Target Neighborhood Hits	1058	Shared Neighborhood Hits	51
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

FBX42_HUMAN
NC score	0.005802 (rank : 457)	θ value	5.27518 (rank : 412)
Query Neighborhood Hits	455	Target Neighborhood Hits	121	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

RBMX2_HUMAN
NC score	0.005700 (rank : 458)	θ value	2.36792 (rank : 369)
Query Neighborhood Hits	455	Target Neighborhood Hits	351	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y388, Q5JY82, Q9Y3I8	Gene names	RBMX2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

IRX5_MOUSE
NC score	0.005684 (rank : 459)	θ value	3.0926 (rank : 383)
Query Neighborhood Hits	455	Target Neighborhood Hits	324	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

MEF2D_HUMAN
NC score	0.005265 (rank : 460)	θ value	5.27518 (rank : 415)
Query Neighborhood Hits	455	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

ST5_HUMAN
NC score	0.005045 (rank : 461)	θ value	4.03905 (rank : 405)
Query Neighborhood Hits	455	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

RTEL1_HUMAN
NC score	0.004768 (rank : 462)	θ value	6.88961 (rank : 434)
Query Neighborhood Hits	455	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

CO9A2_MOUSE
NC score	0.004697 (rank : 463)	θ value	1.38821 (rank : 341)
Query Neighborhood Hits	455	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

KCNQ3_MOUSE
NC score	0.004577 (rank : 464)	θ value	6.88961 (rank : 429)
Query Neighborhood Hits	455	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

CAC1H_HUMAN
NC score	0.004565 (rank : 465)	θ value	3.0926 (rank : 378)
Query Neighborhood Hits	455	Target Neighborhood Hits	307	Shared Neighborhood Hits	28
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

KCNQ3_HUMAN
NC score	0.004311 (rank : 466)	θ value	6.88961 (rank : 428)
Query Neighborhood Hits	455	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

TIF1G_MOUSE
NC score	0.004179 (rank : 467)	θ value	1.81305 (rank : 363)
Query Neighborhood Hits	455	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

MSH5_HUMAN
NC score	0.004095 (rank : 468)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	455	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.

CAC1B_HUMAN
NC score	0.003833 (rank : 469)	θ value	3.0926 (rank : 377)
Query Neighborhood Hits	455	Target Neighborhood Hits	257	Shared Neighborhood Hits	23
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

COIA1_MOUSE
NC score	0.003491 (rank : 470)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	455	Target Neighborhood Hits	481	Shared Neighborhood Hits	40
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

SPAG4_MOUSE
NC score	0.003262 (rank : 471)	θ value	6.88961 (rank : 437)
Query Neighborhood Hits	455	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJF2	Gene names	Spag4
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 4 protein (Outer dense fiber-associated protein SPAG4).

MARCO_HUMAN
NC score	0.002990 (rank : 472)	θ value	4.03905 (rank : 398)
Query Neighborhood Hits	455	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

FOG1_MOUSE
NC score	0.002735 (rank : 473)	θ value	1.81305 (rank : 356)
Query Neighborhood Hits	455	Target Neighborhood Hits	1237	Shared Neighborhood Hits	73
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

FOG2_HUMAN
NC score	0.002364 (rank : 474)	θ value	0.0252991 (rank : 285)
Query Neighborhood Hits	455	Target Neighborhood Hits	731	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

SPTN4_HUMAN
NC score	0.002085 (rank : 475)	θ value	4.03905 (rank : 404)
Query Neighborhood Hits	455	Target Neighborhood Hits	570	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

NDST2_MOUSE
NC score	0.000212 (rank : 476)	θ value	6.88961 (rank : 432)
Query Neighborhood Hits	455	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

MAGI2_HUMAN
NC score	-0.000260 (rank : 477)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	455	Target Neighborhood Hits	373	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MMP10_HUMAN
NC score	-0.001612 (rank : 478)	θ value	5.27518 (rank : 416)
Query Neighborhood Hits	455	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P09238	Gene names	MMP10, STMY2
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

ROBO1_HUMAN
NC score	-0.004142 (rank : 479)	θ value	1.06291 (rank : 337)
Query Neighborhood Hits	455	Target Neighborhood Hits	529	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ZN447_HUMAN
NC score	-0.005076 (rank : 480)	θ value	3.0926 (rank : 391)
Query Neighborhood Hits	455	Target Neighborhood Hits	899	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

ZEP2_HUMAN
NC score	-0.008401 (rank : 481)	θ value	6.88961 (rank : 439)
Query Neighborhood Hits	455	Target Neighborhood Hits	937	Shared Neighborhood Hits	35
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

HME2_HUMAN
NC score	-0.008497 (rank : 482)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	455	Target Neighborhood Hits	355	Shared Neighborhood Hits	4
SwissProt Accessions	P19622	Gene names	EN2
Domain Architecture
Description	Homeobox protein engrailed-2 (Hu-En-2).

GLI1_MOUSE
NC score	-0.010854 (rank : 483)	θ value	2.36792 (rank : 365)
Query Neighborhood Hits	455	Target Neighborhood Hits	785	Shared Neighborhood Hits	22
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

ZN445_HUMAN
NC score	-0.011534 (rank : 484)	θ value	0.279714 (rank : 319)
Query Neighborhood Hits	455	Target Neighborhood Hits	764	Shared Neighborhood Hits	18
SwissProt Accessions	P59923	Gene names	ZNF445, ZNF168
Domain Architecture
Description	Zinc finger protein 445.

ZN509_MOUSE
NC score	-0.011654 (rank : 485)	θ value	0.62314 (rank : 332)
Query Neighborhood Hits	455	Target Neighborhood Hits	990	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN394_HUMAN
NC score	-0.012833 (rank : 486)	θ value	6.88961 (rank : 440)
Query Neighborhood Hits	455	Target Neighborhood Hits	752	Shared Neighborhood Hits	16
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.