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Network neighborhood for query Sequence : RNF12_HUMAN

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RNF12_HUMAN
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RNF12_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	173	Target Neighborhood Hits	173	Shared Neighborhood Hits	173
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF12_MOUSE
θ value	1.90044e-183 (rank : 2)	NC score	0.973585 (rank : 2)
Query Neighborhood Hits	173	Target Neighborhood Hits	159	Shared Neighborhood Hits	111
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF6_HUMAN
θ value	1.40363e-77 (rank : 3)	NC score	0.928925 (rank : 3)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF13_HUMAN
θ value	1.29331e-14 (rank : 4)	NC score	0.693716 (rank : 10)
Query Neighborhood Hits	173	Target Neighborhood Hits	147	Shared Neighborhood Hits	84
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	1.29331e-14 (rank : 5)	NC score	0.696773 (rank : 6)
Query Neighborhood Hits	173	Target Neighborhood Hits	164	Shared Neighborhood Hits	86
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RN167_HUMAN
θ value	3.76295e-14 (rank : 6)	NC score	0.701622 (rank : 4)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	3.76295e-14 (rank : 7)	NC score	0.698947 (rank : 5)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF38_HUMAN
θ value	5.43371e-13 (rank : 8)	NC score	0.695826 (rank : 8)
Query Neighborhood Hits	173	Target Neighborhood Hits	155	Shared Neighborhood Hits	94
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF38_MOUSE
θ value	2.69671e-12 (rank : 9)	NC score	0.690523 (rank : 11)
Query Neighborhood Hits	173	Target Neighborhood Hits	153	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

GOLI_MOUSE
θ value	7.34386e-10 (rank : 10)	NC score	0.661488 (rank : 13)
Query Neighborhood Hits	173	Target Neighborhood Hits	134	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
θ value	9.59137e-10 (rank : 11)	NC score	0.657876 (rank : 14)
Query Neighborhood Hits	173	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RN126_HUMAN
θ value	1.06045e-08 (rank : 12)	NC score	0.628154 (rank : 19)
Query Neighborhood Hits	173	Target Neighborhood Hits	126	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	1.38499e-08 (rank : 13)	NC score	0.633735 (rank : 15)
Query Neighborhood Hits	173	Target Neighborhood Hits	143	Shared Neighborhood Hits	94
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN165_HUMAN
θ value	1.38499e-08 (rank : 14)	NC score	0.681352 (rank : 12)
Query Neighborhood Hits	173	Target Neighborhood Hits	151	Shared Neighborhood Hits	94
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

ZN364_MOUSE
θ value	1.38499e-08 (rank : 15)	NC score	0.624060 (rank : 21)
Query Neighborhood Hits	173	Target Neighborhood Hits	140	Shared Neighborhood Hits	90
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RNF11_HUMAN
θ value	2.36244e-08 (rank : 16)	NC score	0.696418 (rank : 7)
Query Neighborhood Hits	173	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	2.36244e-08 (rank : 17)	NC score	0.694518 (rank : 9)
Query Neighborhood Hits	173	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

ZN364_HUMAN
θ value	3.08544e-08 (rank : 18)	NC score	0.624431 (rank : 20)
Query Neighborhood Hits	173	Target Neighborhood Hits	140	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

PJA1_HUMAN
θ value	1.17247e-07 (rank : 19)	NC score	0.584995 (rank : 25)
Query Neighborhood Hits	173	Target Neighborhood Hits	159	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	1.17247e-07 (rank : 20)	NC score	0.593559 (rank : 24)
Query Neighborhood Hits	173	Target Neighborhood Hits	145	Shared Neighborhood Hits	89
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RN122_HUMAN
θ value	6.43352e-06 (rank : 21)	NC score	0.631561 (rank : 17)
Query Neighborhood Hits	173	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	6.43352e-06 (rank : 22)	NC score	0.632542 (rank : 16)
Query Neighborhood Hits	173	Target Neighborhood Hits	121	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN133_HUMAN
θ value	6.43352e-06 (rank : 23)	NC score	0.629221 (rank : 18)
Query Neighborhood Hits	173	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

DZIP3_HUMAN
θ value	1.87187e-05 (rank : 24)	NC score	0.423428 (rank : 36)
Query Neighborhood Hits	173	Target Neighborhood Hits	399	Shared Neighborhood Hits	89
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	3.19293e-05 (rank : 25)	NC score	0.425294 (rank : 35)
Query Neighborhood Hits	173	Target Neighborhood Hits	414	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

RNF24_HUMAN
θ value	4.1701e-05 (rank : 26)	NC score	0.603967 (rank : 23)
Query Neighborhood Hits	173	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	4.1701e-05 (rank : 27)	NC score	0.605512 (rank : 22)
Query Neighborhood Hits	173	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

ZSWM2_MOUSE
θ value	4.1701e-05 (rank : 28)	NC score	0.454846 (rank : 32)
Query Neighborhood Hits	173	Target Neighborhood Hits	132	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

AMFR_MOUSE
θ value	5.44631e-05 (rank : 29)	NC score	0.468136 (rank : 28)
Query Neighborhood Hits	173	Target Neighborhood Hits	208	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
θ value	7.1131e-05 (rank : 30)	NC score	0.465618 (rank : 29)
Query Neighborhood Hits	173	Target Neighborhood Hits	219	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RN103_MOUSE
θ value	0.000121331 (rank : 31)	NC score	0.460117 (rank : 30)
Query Neighborhood Hits	173	Target Neighborhood Hits	143	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN139_HUMAN
θ value	0.000158464 (rank : 32)	NC score	0.490733 (rank : 26)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
θ value	0.000158464 (rank : 33)	NC score	0.483247 (rank : 27)
Query Neighborhood Hits	173	Target Neighborhood Hits	131	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN103_HUMAN
θ value	0.00035302 (rank : 34)	NC score	0.458229 (rank : 31)
Query Neighborhood Hits	173	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN141_MOUSE
θ value	0.00035302 (rank : 35)	NC score	0.442654 (rank : 33)
Query Neighborhood Hits	173	Target Neighborhood Hits	200	Shared Neighborhood Hits	81
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

ZSWM2_HUMAN
θ value	0.000602161 (rank : 36)	NC score	0.419769 (rank : 37)
Query Neighborhood Hits	173	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

BRAP_HUMAN
θ value	0.00102713 (rank : 37)	NC score	0.245105 (rank : 59)
Query Neighborhood Hits	173	Target Neighborhood Hits	560	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	0.00102713 (rank : 38)	NC score	0.276466 (rank : 49)
Query Neighborhood Hits	173	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

TTC3_HUMAN
θ value	0.00134147 (rank : 39)	NC score	0.256299 (rank : 52)
Query Neighborhood Hits	173	Target Neighborhood Hits	664	Shared Neighborhood Hits	78
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

RN141_HUMAN
θ value	0.00298849 (rank : 40)	NC score	0.433534 (rank : 34)
Query Neighborhood Hits	173	Target Neighborhood Hits	199	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

MDM4_HUMAN
θ value	0.00665767 (rank : 41)	NC score	0.114382 (rank : 93)
Query Neighborhood Hits	173	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MYCB2_MOUSE
θ value	0.00665767 (rank : 42)	NC score	0.157246 (rank : 77)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

CKAP2_HUMAN
θ value	0.00869519 (rank : 43)	NC score	0.095917 (rank : 103)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

MYCB2_HUMAN
θ value	0.00869519 (rank : 44)	NC score	0.158060 (rank : 74)
Query Neighborhood Hits	173	Target Neighborhood Hits	390	Shared Neighborhood Hits	53
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RAPSN_HUMAN
θ value	0.0148317 (rank : 45)	NC score	0.248888 (rank : 55)
Query Neighborhood Hits	173	Target Neighborhood Hits	84	Shared Neighborhood Hits	44
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
θ value	0.0148317 (rank : 46)	NC score	0.246051 (rank : 58)
Query Neighborhood Hits	173	Target Neighborhood Hits	92	Shared Neighborhood Hits	45
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RNF8_HUMAN
θ value	0.0148317 (rank : 47)	NC score	0.240620 (rank : 62)
Query Neighborhood Hits	173	Target Neighborhood Hits	622	Shared Neighborhood Hits	94
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

ZN363_HUMAN
θ value	0.0148317 (rank : 48)	NC score	0.338621 (rank : 41)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	51
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	0.0148317 (rank : 49)	NC score	0.346982 (rank : 40)
Query Neighborhood Hits	173	Target Neighborhood Hits	134	Shared Neighborhood Hits	51
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

TRI65_MOUSE
θ value	0.0193708 (rank : 50)	NC score	0.159028 (rank : 73)
Query Neighborhood Hits	173	Target Neighborhood Hits	340	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

FILA_HUMAN
θ value	0.0252991 (rank : 51)	NC score	0.069980 (rank : 126)
Query Neighborhood Hits	173	Target Neighborhood Hits	685	Shared Neighborhood Hits	37
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

RBX1_HUMAN
θ value	0.0252991 (rank : 52)	NC score	0.298354 (rank : 43)
Query Neighborhood Hits	173	Target Neighborhood Hits	51	Shared Neighborhood Hits	44
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
θ value	0.0252991 (rank : 53)	NC score	0.298354 (rank : 44)
Query Neighborhood Hits	173	Target Neighborhood Hits	51	Shared Neighborhood Hits	44
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

RNF8_MOUSE
θ value	0.0330416 (rank : 54)	NC score	0.246348 (rank : 56)
Query Neighborhood Hits	173	Target Neighborhood Hits	618	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SRRM2_HUMAN
θ value	0.0563607 (rank : 55)	NC score	0.067076 (rank : 131)
Query Neighborhood Hits	173	Target Neighborhood Hits	1296	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRAIP_HUMAN
θ value	0.0736092 (rank : 56)	NC score	0.173357 (rank : 70)
Query Neighborhood Hits	173	Target Neighborhood Hits	780	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	0.0736092 (rank : 57)	NC score	0.174166 (rank : 67)
Query Neighborhood Hits	173	Target Neighborhood Hits	745	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

EYA1_HUMAN
θ value	0.0961366 (rank : 58)	NC score	0.037540 (rank : 176)
Query Neighborhood Hits	173	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q99502	Gene names	EYA1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

MDM4_MOUSE
θ value	0.0961366 (rank : 59)	NC score	0.098663 (rank : 101)
Query Neighborhood Hits	173	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

APC11_MOUSE
θ value	0.125558 (rank : 60)	NC score	0.297755 (rank : 45)
Query Neighborhood Hits	173	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

RN175_HUMAN
θ value	0.125558 (rank : 61)	NC score	0.326176 (rank : 42)
Query Neighborhood Hits	173	Target Neighborhood Hits	68	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

CM007_MOUSE
θ value	0.163984 (rank : 62)	NC score	0.186601 (rank : 65)
Query Neighborhood Hits	173	Target Neighborhood Hits	416	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DTX3_HUMAN
θ value	0.163984 (rank : 63)	NC score	0.165815 (rank : 71)
Query Neighborhood Hits	173	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	0.163984 (rank : 64)	NC score	0.163519 (rank : 72)
Query Neighborhood Hits	173	Target Neighborhood Hits	202	Shared Neighborhood Hits	66
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

PEX10_HUMAN
θ value	0.163984 (rank : 65)	NC score	0.288013 (rank : 46)
Query Neighborhood Hits	173	Target Neighborhood Hits	255	Shared Neighborhood Hits	92
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RBX2_HUMAN
θ value	0.163984 (rank : 66)	NC score	0.363948 (rank : 39)
Query Neighborhood Hits	173	Target Neighborhood Hits	83	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	0.163984 (rank : 67)	NC score	0.364563 (rank : 38)
Query Neighborhood Hits	173	Target Neighborhood Hits	82	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RNF25_HUMAN
θ value	0.163984 (rank : 68)	NC score	0.195643 (rank : 64)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RNF25_MOUSE
θ value	0.163984 (rank : 69)	NC score	0.209346 (rank : 63)
Query Neighborhood Hits	173	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

SMAD4_HUMAN
θ value	0.163984 (rank : 70)	NC score	0.026246 (rank : 189)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

APC11_HUMAN
θ value	0.21417 (rank : 71)	NC score	0.285769 (rank : 48)
Query Neighborhood Hits	173	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

CM007_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.175271 (rank : 66)
Query Neighborhood Hits	173	Target Neighborhood Hits	422	Shared Neighborhood Hits	72
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

LEO1_MOUSE
θ value	0.21417 (rank : 73)	NC score	0.027873 (rank : 186)
Query Neighborhood Hits	173	Target Neighborhood Hits	946	Shared Neighborhood Hits	21
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TTC16_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.057582 (rank : 138)
Query Neighborhood Hits	173	Target Neighborhood Hits	417	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

VRK3_HUMAN
θ value	0.21417 (rank : 75)	NC score	0.027343 (rank : 187)
Query Neighborhood Hits	173	Target Neighborhood Hits	349	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

ZN297_MOUSE
θ value	0.21417 (rank : 76)	NC score	0.003838 (rank : 222)
Query Neighborhood Hits	173	Target Neighborhood Hits	816	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0G7	Gene names	Znf297, Bing1, Zfp297
Domain Architecture
Description	Zinc finger protein 297 (BING1 protein).

TRIM2_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.157619 (rank : 75)
Query Neighborhood Hits	173	Target Neighborhood Hits	330	Shared Neighborhood Hits	78
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.157391 (rank : 76)
Query Neighborhood Hits	173	Target Neighborhood Hits	331	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

CHD5_HUMAN
θ value	0.365318 (rank : 79)	NC score	0.030891 (rank : 182)
Query Neighborhood Hits	173	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

GP124_MOUSE
θ value	0.365318 (rank : 80)	NC score	0.015666 (rank : 201)
Query Neighborhood Hits	173	Target Neighborhood Hits	423	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

TRI39_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.079896 (rank : 112)
Query Neighborhood Hits	173	Target Neighborhood Hits	693	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.365318 (rank : 82)	NC score	0.078728 (rank : 115)
Query Neighborhood Hits	173	Target Neighborhood Hits	691	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RNF4_HUMAN
θ value	0.47712 (rank : 83)	NC score	0.244740 (rank : 60)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	78
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	0.47712 (rank : 84)	NC score	0.242787 (rank : 61)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TOPRS_HUMAN
θ value	0.47712 (rank : 85)	NC score	0.253066 (rank : 53)
Query Neighborhood Hits	173	Target Neighborhood Hits	286	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	0.47712 (rank : 86)	NC score	0.257433 (rank : 51)
Query Neighborhood Hits	173	Target Neighborhood Hits	263	Shared Neighborhood Hits	91
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI29_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.050595 (rank : 165)
Query Neighborhood Hits	173	Target Neighborhood Hits	273	Shared Neighborhood Hits	21
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

VPS11_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.118972 (rank : 90)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

VPS11_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.119585 (rank : 89)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

CHFR_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.246228 (rank : 57)
Query Neighborhood Hits	173	Target Neighborhood Hits	255	Shared Neighborhood Hits	79
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	0.813845 (rank : 91)	NC score	0.249118 (rank : 54)
Query Neighborhood Hits	173	Target Neighborhood Hits	264	Shared Neighborhood Hits	78
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

SFRS4_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.036675 (rank : 177)
Query Neighborhood Hits	173	Target Neighborhood Hits	384	Shared Neighborhood Hits	24
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SUHW1_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.006310 (rank : 217)
Query Neighborhood Hits	173	Target Neighborhood Hits	648	Shared Neighborhood Hits	8
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

TARA_HUMAN
θ value	0.813845 (rank : 94)	NC score	0.053047 (rank : 154)
Query Neighborhood Hits	173	Target Neighborhood Hits	1626	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRI13_MOUSE
θ value	0.813845 (rank : 95)	NC score	0.114823 (rank : 92)
Query Neighborhood Hits	173	Target Neighborhood Hits	282	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI50_MOUSE
θ value	0.813845 (rank : 96)	NC score	0.064813 (rank : 134)
Query Neighborhood Hits	173	Target Neighborhood Hits	326	Shared Neighborhood Hits	60
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRIM3_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.138943 (rank : 80)
Query Neighborhood Hits	173	Target Neighborhood Hits	357	Shared Neighborhood Hits	75
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	0.813845 (rank : 98)	NC score	0.134879 (rank : 84)
Query Neighborhood Hits	173	Target Neighborhood Hits	351	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

LIPB2_MOUSE
θ value	1.06291 (rank : 99)	NC score	0.014061 (rank : 202)
Query Neighborhood Hits	173	Target Neighborhood Hits	570	Shared Neighborhood Hits	9
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

MUC13_MOUSE
θ value	1.06291 (rank : 100)	NC score	0.031240 (rank : 181)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SFRS4_MOUSE
θ value	1.06291 (rank : 101)	NC score	0.044175 (rank : 174)
Query Neighborhood Hits	173	Target Neighborhood Hits	406	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TRI13_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.111659 (rank : 95)
Query Neighborhood Hits	173	Target Neighborhood Hits	274	Shared Neighborhood Hits	73
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

AT10B_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.010205 (rank : 213)
Query Neighborhood Hits	173	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O94823, Q9H725	Gene names	ATP10B, ATPVB, KIAA0715
Domain Architecture
Description	Probable phospholipid-transporting ATPase VB (EC 3.6.3.1).

CHD3_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.030758 (rank : 183)
Query Neighborhood Hits	173	Target Neighborhood Hits	397	Shared Neighborhood Hits	23
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

COHA1_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.018258 (rank : 197)
Query Neighborhood Hits	173	Target Neighborhood Hits	400	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

PDZD2_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.019528 (rank : 195)
Query Neighborhood Hits	173	Target Neighborhood Hits	772	Shared Neighborhood Hits	22
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RNF41_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.173663 (rank : 68)
Query Neighborhood Hits	173	Target Neighborhood Hits	226	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	1.38821 (rank : 108)	NC score	0.173650 (rank : 69)
Query Neighborhood Hits	173	Target Neighborhood Hits	224	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SFR16_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.056006 (rank : 143)
Query Neighborhood Hits	173	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N2M8, O96026, Q6UW71, Q96DX2	Gene names	SFRS16, SWAP2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2).

EYA1_MOUSE
θ value	1.81305 (rank : 110)	NC score	0.030142 (rank : 184)
Query Neighborhood Hits	173	Target Neighborhood Hits	108	Shared Neighborhood Hits	9
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

M3K15_HUMAN
θ value	1.81305 (rank : 111)	NC score	-0.001848 (rank : 226)
Query Neighborhood Hits	173	Target Neighborhood Hits	914	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

PGCA_MOUSE
θ value	1.81305 (rank : 112)	NC score	0.011816 (rank : 207)
Query Neighborhood Hits	173	Target Neighborhood Hits	643	Shared Neighborhood Hits	17
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

RAD18_HUMAN
θ value	1.81305 (rank : 113)	NC score	0.135518 (rank : 82)
Query Neighborhood Hits	173	Target Neighborhood Hits	284	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	1.81305 (rank : 114)	NC score	0.135285 (rank : 83)
Query Neighborhood Hits	173	Target Neighborhood Hits	230	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

CBLC_HUMAN
θ value	2.36792 (rank : 115)	NC score	0.112566 (rank : 94)
Query Neighborhood Hits	173	Target Neighborhood Hits	173	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

ZN294_HUMAN
θ value	2.36792 (rank : 116)	NC score	0.094078 (rank : 106)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

ZN294_MOUSE
θ value	2.36792 (rank : 117)	NC score	0.094522 (rank : 105)
Query Neighborhood Hits	173	Target Neighborhood Hits	81	Shared Neighborhood Hits	41
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

DTX3L_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.138074 (rank : 81)
Query Neighborhood Hits	173	Target Neighborhood Hits	187	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

INVS_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.007133 (rank : 215)
Query Neighborhood Hits	173	Target Neighborhood Hits	455	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

LNX1_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.050040 (rank : 170)
Query Neighborhood Hits	173	Target Neighborhood Hits	377	Shared Neighborhood Hits	53
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RIMS1_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.024189 (rank : 192)
Query Neighborhood Hits	173	Target Neighborhood Hits	437	Shared Neighborhood Hits	19
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SON_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.010396 (rank : 212)
Query Neighborhood Hits	173	Target Neighborhood Hits	1568	Shared Neighborhood Hits	25
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TARA_MOUSE
θ value	3.0926 (rank : 123)	NC score	0.032291 (rank : 180)
Query Neighborhood Hits	173	Target Neighborhood Hits	1133	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRI29_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.044661 (rank : 173)
Query Neighborhood Hits	173	Target Neighborhood Hits	306	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

CBLC_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.138960 (rank : 79)
Query Neighborhood Hits	173	Target Neighborhood Hits	186	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

K0082_MOUSE
θ value	4.03905 (rank : 126)	NC score	0.016967 (rank : 198)
Query Neighborhood Hits	173	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBC3, Q3U3G5, Q3U7Y9, Q6A0D5, Q8C7V0	Gene names	Kiaa0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

NMDE2_HUMAN
θ value	4.03905 (rank : 127)	NC score	0.013106 (rank : 204)
Query Neighborhood Hits	173	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
θ value	4.03905 (rank : 128)	NC score	0.013103 (rank : 205)
Query Neighborhood Hits	173	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NSMA2_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.020270 (rank : 194)
Query Neighborhood Hits	173	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

RO52_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.053379 (rank : 153)
Query Neighborhood Hits	173	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

SFR16_MOUSE
θ value	4.03905 (rank : 131)	NC score	0.046363 (rank : 172)
Query Neighborhood Hits	173	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CFC7, Q8CFC8, Q9Z2N3	Gene names	Sfrs16, Clasp, Swap2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2) (Clk4-associating SR-related protein).

SRRM2_MOUSE
θ value	4.03905 (rank : 132)	NC score	0.052372 (rank : 158)
Query Neighborhood Hits	173	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TGON2_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.033824 (rank : 179)
Query Neighborhood Hits	173	Target Neighborhood Hits	1037	Shared Neighborhood Hits	40
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TRI65_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.144515 (rank : 78)
Query Neighborhood Hits	173	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ZBT37_HUMAN
θ value	4.03905 (rank : 135)	NC score	-0.000819 (rank : 224)
Query Neighborhood Hits	173	Target Neighborhood Hits	815	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

ZN313_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.118503 (rank : 91)
Query Neighborhood Hits	173	Target Neighborhood Hits	264	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN507_HUMAN
θ value	4.03905 (rank : 137)	NC score	-0.001259 (rank : 225)
Query Neighborhood Hits	173	Target Neighborhood Hits	739	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

CAC1B_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.011266 (rank : 208)
Query Neighborhood Hits	173	Target Neighborhood Hits	351	Shared Neighborhood Hits	11
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

DOCK3_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.010848 (rank : 210)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

GRAM3_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.016378 (rank : 199)
Query Neighborhood Hits	173	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEM6	Gene names	Gramd3
Domain Architecture	No domain graphic available
Description	GRAM domain-containing protein 3.

HORN_MOUSE
θ value	5.27518 (rank : 141)	NC score	0.048379 (rank : 171)
Query Neighborhood Hits	173	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

M3K4_MOUSE
θ value	5.27518 (rank : 142)	NC score	-0.003302 (rank : 228)
Query Neighborhood Hits	173	Target Neighborhood Hits	924	Shared Neighborhood Hits	7
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

NPBL_MOUSE
θ value	5.27518 (rank : 143)	NC score	0.028476 (rank : 185)
Query Neighborhood Hits	173	Target Neighborhood Hits	1041	Shared Neighborhood Hits	34
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SFRIP_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.038484 (rank : 175)
Query Neighborhood Hits	173	Target Neighborhood Hits	530	Shared Neighborhood Hits	26
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

ANRA2_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.002398 (rank : 223)
Query Neighborhood Hits	173	Target Neighborhood Hits	287	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

DKK2_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.010679 (rank : 211)
Query Neighborhood Hits	173	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYZ8	Gene names	Dkk2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (mDkk-2).

E41L2_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.004072 (rank : 220)
Query Neighborhood Hits	173	Target Neighborhood Hits	287	Shared Neighborhood Hits	8
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

GP101_MOUSE
θ value	6.88961 (rank : 148)	NC score	-0.003161 (rank : 227)
Query Neighborhood Hits	173	Target Neighborhood Hits	916	Shared Neighborhood Hits	3
SwissProt Accessions	Q80T62, Q3UUI9	Gene names	Gpr101
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 101.

GRIN1_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.012888 (rank : 206)
Query Neighborhood Hits	173	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

IWS1_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.026801 (rank : 188)
Query Neighborhood Hits	173	Target Neighborhood Hits	1241	Shared Neighborhood Hits	30
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NKTR_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.019325 (rank : 196)
Query Neighborhood Hits	173	Target Neighborhood Hits	658	Shared Neighborhood Hits	28
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

REST_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.004043 (rank : 221)
Query Neighborhood Hits	173	Target Neighborhood Hits	1506	Shared Neighborhood Hits	25
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFWD2_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.068936 (rank : 127)
Query Neighborhood Hits	173	Target Neighborhood Hits	535	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

UHRF1_MOUSE
θ value	6.88961 (rank : 154)	NC score	0.024870 (rank : 190)
Query Neighborhood Hits	173	Target Neighborhood Hits	278	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

DMP1_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.034042 (rank : 178)
Query Neighborhood Hits	173	Target Neighborhood Hits	491	Shared Neighborhood Hits	20
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DOCK3_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.009779 (rank : 214)
Query Neighborhood Hits	173	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

E2AK2_HUMAN
θ value	8.99809 (rank : 157)	NC score	-0.004464 (rank : 231)
Query Neighborhood Hits	173	Target Neighborhood Hits	856	Shared Neighborhood Hits	6
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

LONM_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.011240 (rank : 209)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

LRC50_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.006190 (rank : 218)
Query Neighborhood Hits	173	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2H9, Q9CVS9	Gene names	Lrrc50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MYO3B_HUMAN
θ value	8.99809 (rank : 160)	NC score	-0.003953 (rank : 229)
Query Neighborhood Hits	173	Target Neighborhood Hits	923	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

NU214_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.015743 (rank : 200)
Query Neighborhood Hits	173	Target Neighborhood Hits	657	Shared Neighborhood Hits	16
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PCGF2_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.119894 (rank : 87)
Query Neighborhood Hits	173	Target Neighborhood Hits	222	Shared Neighborhood Hits	68
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.119760 (rank : 88)
Query Neighborhood Hits	173	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

RECQ4_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.005199 (rank : 219)
Query Neighborhood Hits	173	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RFWD2_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.067015 (rank : 132)
Query Neighborhood Hits	173	Target Neighborhood Hits	518	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RN152_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.055580 (rank : 144)
Query Neighborhood Hits	173	Target Neighborhood Hits	107	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.055311 (rank : 145)
Query Neighborhood Hits	173	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TCF20_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.020849 (rank : 193)
Query Neighborhood Hits	173	Target Neighborhood Hits	323	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.024197 (rank : 191)
Query Neighborhood Hits	173	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TRI50_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.054232 (rank : 149)
Query Neighborhood Hits	173	Target Neighborhood Hits	294	Shared Neighborhood Hits	49
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

WDR22_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.006606 (rank : 216)
Query Neighborhood Hits	173	Target Neighborhood Hits	302	Shared Neighborhood Hits	8
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

YETS2_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.013651 (rank : 203)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZKSC1_HUMAN
θ value	8.99809 (rank : 173)	NC score	-0.004023 (rank : 230)
Query Neighborhood Hits	173	Target Neighborhood Hits	949	Shared Neighborhood Hits	16
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

AMFR1_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.050426 (rank : 166)
Query Neighborhood Hits	173	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P26442	Gene names	AMFR
Domain Architecture	No domain graphic available
Description	Autocrine motility factor receptor precursor, isoform 1 (AMF receptor).

BFAR_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.070812 (rank : 125)
Query Neighborhood Hits	173	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.078068 (rank : 116)
Query Neighborhood Hits	173	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

CBLB_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.096521 (rank : 102)
Query Neighborhood Hits	173	Target Neighborhood Hits	261	Shared Neighborhood Hits	62
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.095295 (rank : 104)
Query Neighborhood Hits	173	Target Neighborhood Hits	277	Shared Neighborhood Hits	62
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBL_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.102551 (rank : 99)
Query Neighborhood Hits	173	Target Neighborhood Hits	353	Shared Neighborhood Hits	64
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.100491 (rank : 100)
Query Neighborhood Hits	173	Target Neighborhood Hits	426	Shared Neighborhood Hits	67
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

DSPP_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.050181 (rank : 169)
Query Neighborhood Hits	173	Target Neighborhood Hits	645	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LNX2_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.057096 (rank : 140)
Query Neighborhood Hits	173	Target Neighborhood Hits	389	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.057515 (rank : 139)
Query Neighborhood Hits	173	Target Neighborhood Hits	407	Shared Neighborhood Hits	67
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MGRN1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.081862 (rank : 109)
Query Neighborhood Hits	173	Target Neighborhood Hits	192	Shared Neighborhood Hits	39
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.081008 (rank : 110)
Query Neighborhood Hits	173	Target Neighborhood Hits	149	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MKRN3_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.053612 (rank : 151)
Query Neighborhood Hits	173	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

PCGF4_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.105560 (rank : 96)
Query Neighborhood Hits	173	Target Neighborhood Hits	161	Shared Neighborhood Hits	64
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.103915 (rank : 98)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	63
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF6_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.052084 (rank : 160)
Query Neighborhood Hits	173	Target Neighborhood Hits	178	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.052686 (rank : 155)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PZRN3_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.068003 (rank : 129)
Query Neighborhood Hits	173	Target Neighborhood Hits	461	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.068158 (rank : 128)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	67
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.050898 (rank : 162)
Query Neighborhood Hits	173	Target Neighborhood Hits	438	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RING1_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.079760 (rank : 113)
Query Neighborhood Hits	173	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.079015 (rank : 114)
Query Neighborhood Hits	173	Target Neighborhood Hits	220	Shared Neighborhood Hits	51
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.071877 (rank : 124)
Query Neighborhood Hits	173	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.071964 (rank : 123)
Query Neighborhood Hits	173	Target Neighborhood Hits	199	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN125_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.080595 (rank : 111)
Query Neighborhood Hits	173	Target Neighborhood Hits	230	Shared Neighborhood Hits	49
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.056135 (rank : 142)
Query Neighborhood Hits	173	Target Neighborhood Hits	220	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN146_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.057089 (rank : 141)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.055121 (rank : 146)
Query Neighborhood Hits	173	Target Neighborhood Hits	161	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN166_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.073259 (rank : 120)
Query Neighborhood Hits	173	Target Neighborhood Hits	240	Shared Neighborhood Hits	55
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.072771 (rank : 121)
Query Neighborhood Hits	173	Target Neighborhood Hits	248	Shared Neighborhood Hits	55
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.050975 (rank : 161)
Query Neighborhood Hits	173	Target Neighborhood Hits	370	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.054609 (rank : 147)
Query Neighborhood Hits	173	Target Neighborhood Hits	440	Shared Neighborhood Hits	50
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN185_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.128770 (rank : 85)
Query Neighborhood Hits	173	Target Neighborhood Hits	213	Shared Neighborhood Hits	68
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.125397 (rank : 86)
Query Neighborhood Hits	173	Target Neighborhood Hits	211	Shared Neighborhood Hits	66
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF32_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.285970 (rank : 47)
Query Neighborhood Hits	173	Target Neighborhood Hits	133	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.275708 (rank : 50)
Query Neighborhood Hits	173	Target Neighborhood Hits	129	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF5_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.093702 (rank : 107)
Query Neighborhood Hits	173	Target Neighborhood Hits	206	Shared Neighborhood Hits	60
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.093047 (rank : 108)
Query Neighborhood Hits	173	Target Neighborhood Hits	206	Shared Neighborhood Hits	59
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI12_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.050841 (rank : 163)
Query Neighborhood Hits	173	Target Neighborhood Hits	387	Shared Neighborhood Hits	51
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI25_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.052292 (rank : 159)
Query Neighborhood Hits	173	Target Neighborhood Hits	472	Shared Neighborhood Hits	56
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.063388 (rank : 136)
Query Neighborhood Hits	173	Target Neighborhood Hits	446	Shared Neighborhood Hits	59
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI26_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.053577 (rank : 152)
Query Neighborhood Hits	173	Target Neighborhood Hits	335	Shared Neighborhood Hits	56
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.054115 (rank : 150)
Query Neighborhood Hits	173	Target Neighborhood Hits	339	Shared Neighborhood Hits	59
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI31_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.054524 (rank : 148)
Query Neighborhood Hits	173	Target Neighborhood Hits	299	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.050425 (rank : 167)
Query Neighborhood Hits	173	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI35_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.077261 (rank : 117)
Query Neighborhood Hits	173	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.074906 (rank : 119)
Query Neighborhood Hits	173	Target Neighborhood Hits	465	Shared Neighborhood Hits	57
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.067478 (rank : 130)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.063929 (rank : 135)
Query Neighborhood Hits	173	Target Neighborhood Hits	316	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI40_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.062930 (rank : 137)
Query Neighborhood Hits	173	Target Neighborhood Hits	279	Shared Neighborhood Hits	51
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI56_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.065598 (rank : 133)
Query Neighborhood Hits	173	Target Neighborhood Hits	339	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI59_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.072396 (rank : 122)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.076345 (rank : 118)
Query Neighborhood Hits	173	Target Neighborhood Hits	292	Shared Neighborhood Hits	62
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI73_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.052577 (rank : 156)
Query Neighborhood Hits	173	Target Neighborhood Hits	258	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.050289 (rank : 168)
Query Neighborhood Hits	173	Target Neighborhood Hits	249	Shared Neighborhood Hits	38
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM8_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.052436 (rank : 157)
Query Neighborhood Hits	173	Target Neighborhood Hits	650	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.050612 (rank : 164)
Query Neighborhood Hits	173	Target Neighborhood Hits	674	Shared Neighborhood Hits	47
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZN313_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.104079 (rank : 97)
Query Neighborhood Hits	173	Target Neighborhood Hits	273	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

RNF12_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	173	Target Neighborhood Hits	173	Shared Neighborhood Hits	173
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF12_MOUSE
NC score	0.973585 (rank : 2)	θ value	1.90044e-183 (rank : 2)
Query Neighborhood Hits	173	Target Neighborhood Hits	159	Shared Neighborhood Hits	111
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF6_HUMAN
NC score	0.928925 (rank : 3)	θ value	1.40363e-77 (rank : 3)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RN167_HUMAN
NC score	0.701622 (rank : 4)	θ value	3.76295e-14 (rank : 6)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
NC score	0.698947 (rank : 5)	θ value	3.76295e-14 (rank : 7)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF13_MOUSE
NC score	0.696773 (rank : 6)	θ value	1.29331e-14 (rank : 5)
Query Neighborhood Hits	173	Target Neighborhood Hits	164	Shared Neighborhood Hits	86
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF11_HUMAN
NC score	0.696418 (rank : 7)	θ value	2.36244e-08 (rank : 16)
Query Neighborhood Hits	173	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF38_HUMAN
NC score	0.695826 (rank : 8)	θ value	5.43371e-13 (rank : 8)
Query Neighborhood Hits	173	Target Neighborhood Hits	155	Shared Neighborhood Hits	94
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF11_MOUSE
NC score	0.694518 (rank : 9)	θ value	2.36244e-08 (rank : 17)
Query Neighborhood Hits	173	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RNF13_HUMAN
NC score	0.693716 (rank : 10)	θ value	1.29331e-14 (rank : 4)
Query Neighborhood Hits	173	Target Neighborhood Hits	147	Shared Neighborhood Hits	84
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF38_MOUSE
NC score	0.690523 (rank : 11)	θ value	2.69671e-12 (rank : 9)
Query Neighborhood Hits	173	Target Neighborhood Hits	153	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN165_HUMAN
NC score	0.681352 (rank : 12)	θ value	1.38499e-08 (rank : 14)
Query Neighborhood Hits	173	Target Neighborhood Hits	151	Shared Neighborhood Hits	94
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

GOLI_MOUSE
NC score	0.661488 (rank : 13)	θ value	7.34386e-10 (rank : 10)
Query Neighborhood Hits	173	Target Neighborhood Hits	134	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
NC score	0.657876 (rank : 14)	θ value	9.59137e-10 (rank : 11)
Query Neighborhood Hits	173	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RN126_MOUSE
NC score	0.633735 (rank : 15)	θ value	1.38499e-08 (rank : 13)
Query Neighborhood Hits	173	Target Neighborhood Hits	143	Shared Neighborhood Hits	94
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN122_MOUSE
NC score	0.632542 (rank : 16)	θ value	6.43352e-06 (rank : 22)
Query Neighborhood Hits	173	Target Neighborhood Hits	121	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_HUMAN
NC score	0.631561 (rank : 17)	θ value	6.43352e-06 (rank : 21)
Query Neighborhood Hits	173	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN133_HUMAN
NC score	0.629221 (rank : 18)	θ value	6.43352e-06 (rank : 23)
Query Neighborhood Hits	173	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RN126_HUMAN
NC score	0.628154 (rank : 19)	θ value	1.06045e-08 (rank : 12)
Query Neighborhood Hits	173	Target Neighborhood Hits	126	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

ZN364_HUMAN
NC score	0.624431 (rank : 20)	θ value	3.08544e-08 (rank : 18)
Query Neighborhood Hits	173	Target Neighborhood Hits	140	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
NC score	0.624060 (rank : 21)	θ value	1.38499e-08 (rank : 15)
Query Neighborhood Hits	173	Target Neighborhood Hits	140	Shared Neighborhood Hits	90
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RNF24_MOUSE
NC score	0.605512 (rank : 22)	θ value	4.1701e-05 (rank : 27)
Query Neighborhood Hits	173	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.603967 (rank : 23)	θ value	4.1701e-05 (rank : 26)
Query Neighborhood Hits	173	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

PJA1_MOUSE
NC score	0.593559 (rank : 24)	θ value	1.17247e-07 (rank : 20)
Query Neighborhood Hits	173	Target Neighborhood Hits	145	Shared Neighborhood Hits	89
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PJA1_HUMAN
NC score	0.584995 (rank : 25)	θ value	1.17247e-07 (rank : 19)
Query Neighborhood Hits	173	Target Neighborhood Hits	159	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RN139_HUMAN
NC score	0.490733 (rank : 26)	θ value	0.000158464 (rank : 32)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
NC score	0.483247 (rank : 27)	θ value	0.000158464 (rank : 33)
Query Neighborhood Hits	173	Target Neighborhood Hits	131	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

AMFR_MOUSE
NC score	0.468136 (rank : 28)	θ value	5.44631e-05 (rank : 29)
Query Neighborhood Hits	173	Target Neighborhood Hits	208	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.465618 (rank : 29)	θ value	7.1131e-05 (rank : 30)
Query Neighborhood Hits	173	Target Neighborhood Hits	219	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RN103_MOUSE
NC score	0.460117 (rank : 30)	θ value	0.000121331 (rank : 31)
Query Neighborhood Hits	173	Target Neighborhood Hits	143	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN103_HUMAN
NC score	0.458229 (rank : 31)	θ value	0.00035302 (rank : 34)
Query Neighborhood Hits	173	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

ZSWM2_MOUSE
NC score	0.454846 (rank : 32)	θ value	4.1701e-05 (rank : 28)
Query Neighborhood Hits	173	Target Neighborhood Hits	132	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN141_MOUSE
NC score	0.442654 (rank : 33)	θ value	0.00035302 (rank : 35)
Query Neighborhood Hits	173	Target Neighborhood Hits	200	Shared Neighborhood Hits	81
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.433534 (rank : 34)	θ value	0.00298849 (rank : 40)
Query Neighborhood Hits	173	Target Neighborhood Hits	199	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

DZIP3_MOUSE
NC score	0.425294 (rank : 35)	θ value	3.19293e-05 (rank : 25)
Query Neighborhood Hits	173	Target Neighborhood Hits	414	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DZIP3_HUMAN
NC score	0.423428 (rank : 36)	θ value	1.87187e-05 (rank : 24)
Query Neighborhood Hits	173	Target Neighborhood Hits	399	Shared Neighborhood Hits	89
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

ZSWM2_HUMAN
NC score	0.419769 (rank : 37)	θ value	0.000602161 (rank : 36)
Query Neighborhood Hits	173	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RBX2_MOUSE
NC score	0.364563 (rank : 38)	θ value	0.163984 (rank : 67)
Query Neighborhood Hits	173	Target Neighborhood Hits	82	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RBX2_HUMAN
NC score	0.363948 (rank : 39)	θ value	0.163984 (rank : 66)
Query Neighborhood Hits	173	Target Neighborhood Hits	83	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

ZN363_MOUSE
NC score	0.346982 (rank : 40)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	173	Target Neighborhood Hits	134	Shared Neighborhood Hits	51
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN363_HUMAN
NC score	0.338621 (rank : 41)	θ value	0.0148317 (rank : 48)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	51
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

RN175_HUMAN
NC score	0.326176 (rank : 42)	θ value	0.125558 (rank : 61)
Query Neighborhood Hits	173	Target Neighborhood Hits	68	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

RBX1_HUMAN
NC score	0.298354 (rank : 43)	θ value	0.0252991 (rank : 52)
Query Neighborhood Hits	173	Target Neighborhood Hits	51	Shared Neighborhood Hits	44
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
NC score	0.298354 (rank : 44)	θ value	0.0252991 (rank : 53)
Query Neighborhood Hits	173	Target Neighborhood Hits	51	Shared Neighborhood Hits	44
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

APC11_MOUSE
NC score	0.297755 (rank : 45)	θ value	0.125558 (rank : 60)
Query Neighborhood Hits	173	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

PEX10_HUMAN
NC score	0.288013 (rank : 46)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	173	Target Neighborhood Hits	255	Shared Neighborhood Hits	92
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RNF32_HUMAN
NC score	0.285970 (rank : 47)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	173	Target Neighborhood Hits	133	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

APC11_HUMAN
NC score	0.285769 (rank : 48)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	173	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

BRAP_MOUSE
NC score	0.276466 (rank : 49)	θ value	0.00102713 (rank : 38)
Query Neighborhood Hits	173	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

RNF32_MOUSE
NC score	0.275708 (rank : 50)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	173	Target Neighborhood Hits	129	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

TOPRS_MOUSE
NC score	0.257433 (rank : 51)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	173	Target Neighborhood Hits	263	Shared Neighborhood Hits	91
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TTC3_HUMAN
NC score	0.256299 (rank : 52)	θ value	0.00134147 (rank : 39)
Query Neighborhood Hits	173	Target Neighborhood Hits	664	Shared Neighborhood Hits	78
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TOPRS_HUMAN
NC score	0.253066 (rank : 53)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	173	Target Neighborhood Hits	286	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CHFR_MOUSE
NC score	0.249118 (rank : 54)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	173	Target Neighborhood Hits	264	Shared Neighborhood Hits	78
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RAPSN_HUMAN
NC score	0.248888 (rank : 55)	θ value	0.0148317 (rank : 45)
Query Neighborhood Hits	173	Target Neighborhood Hits	84	Shared Neighborhood Hits	44
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RNF8_MOUSE
NC score	0.246348 (rank : 56)	θ value	0.0330416 (rank : 54)
Query Neighborhood Hits	173	Target Neighborhood Hits	618	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

CHFR_HUMAN
NC score	0.246228 (rank : 57)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	173	Target Neighborhood Hits	255	Shared Neighborhood Hits	79
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RAPSN_MOUSE
NC score	0.246051 (rank : 58)	θ value	0.0148317 (rank : 46)
Query Neighborhood Hits	173	Target Neighborhood Hits	92	Shared Neighborhood Hits	45
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

BRAP_HUMAN
NC score	0.245105 (rank : 59)	θ value	0.00102713 (rank : 37)
Query Neighborhood Hits	173	Target Neighborhood Hits	560	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RNF4_HUMAN
NC score	0.244740 (rank : 60)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	78
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.242787 (rank : 61)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF8_HUMAN
NC score	0.240620 (rank : 62)	θ value	0.0148317 (rank : 47)
Query Neighborhood Hits	173	Target Neighborhood Hits	622	Shared Neighborhood Hits	94
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF25_MOUSE
NC score	0.209346 (rank : 63)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	173	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RNF25_HUMAN
NC score	0.195643 (rank : 64)	θ value	0.163984 (rank : 68)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

CM007_MOUSE
NC score	0.186601 (rank : 65)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	173	Target Neighborhood Hits	416	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CM007_HUMAN
NC score	0.175271 (rank : 66)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	173	Target Neighborhood Hits	422	Shared Neighborhood Hits	72
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRAIP_MOUSE
NC score	0.174166 (rank : 67)	θ value	0.0736092 (rank : 57)
Query Neighborhood Hits	173	Target Neighborhood Hits	745	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

RNF41_HUMAN
NC score	0.173663 (rank : 68)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	173	Target Neighborhood Hits	226	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.173650 (rank : 69)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	173	Target Neighborhood Hits	224	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRAIP_HUMAN
NC score	0.173357 (rank : 70)	θ value	0.0736092 (rank : 56)
Query Neighborhood Hits	173	Target Neighborhood Hits	780	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

DTX3_HUMAN
NC score	0.165815 (rank : 71)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	173	Target Neighborhood Hits	198	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
NC score	0.163519 (rank : 72)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	173	Target Neighborhood Hits	202	Shared Neighborhood Hits	66
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TRI65_MOUSE
NC score	0.159028 (rank : 73)	θ value	0.0193708 (rank : 50)
Query Neighborhood Hits	173	Target Neighborhood Hits	340	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

MYCB2_HUMAN
NC score	0.158060 (rank : 74)	θ value	0.00869519 (rank : 44)
Query Neighborhood Hits	173	Target Neighborhood Hits	390	Shared Neighborhood Hits	53
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TRIM2_HUMAN
NC score	0.157619 (rank : 75)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	173	Target Neighborhood Hits	330	Shared Neighborhood Hits	78
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.157391 (rank : 76)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	173	Target Neighborhood Hits	331	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

MYCB2_MOUSE
NC score	0.157246 (rank : 77)	θ value	0.00665767 (rank : 42)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TRI65_HUMAN
NC score	0.144515 (rank : 78)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	173	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CBLC_MOUSE
NC score	0.138960 (rank : 79)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	173	Target Neighborhood Hits	186	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

TRIM3_HUMAN
NC score	0.138943 (rank : 80)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	173	Target Neighborhood Hits	357	Shared Neighborhood Hits	75
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

DTX3L_HUMAN
NC score	0.138074 (rank : 81)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	173	Target Neighborhood Hits	187	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RAD18_HUMAN
NC score	0.135518 (rank : 82)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	173	Target Neighborhood Hits	284	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
NC score	0.135285 (rank : 83)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	173	Target Neighborhood Hits	230	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

TRIM3_MOUSE
NC score	0.134879 (rank : 84)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	173	Target Neighborhood Hits	351	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

RN185_HUMAN
NC score	0.128770 (rank : 85)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	173	Target Neighborhood Hits	213	Shared Neighborhood Hits	68
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.125397 (rank : 86)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	173	Target Neighborhood Hits	211	Shared Neighborhood Hits	66
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

PCGF2_HUMAN
NC score	0.119894 (rank : 87)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	173	Target Neighborhood Hits	222	Shared Neighborhood Hits	68
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.119760 (rank : 88)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	173	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

VPS11_MOUSE
NC score	0.119585 (rank : 89)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

VPS11_HUMAN
NC score	0.118972 (rank : 90)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

ZN313_HUMAN
NC score	0.118503 (rank : 91)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	173	Target Neighborhood Hits	264	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRI13_MOUSE
NC score	0.114823 (rank : 92)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	173	Target Neighborhood Hits	282	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

MDM4_HUMAN
NC score	0.114382 (rank : 93)	θ value	0.00665767 (rank : 41)
Query Neighborhood Hits	173	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

CBLC_HUMAN
NC score	0.112566 (rank : 94)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	173	Target Neighborhood Hits	173	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

TRI13_HUMAN
NC score	0.111659 (rank : 95)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	173	Target Neighborhood Hits	274	Shared Neighborhood Hits	73
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

PCGF4_HUMAN
NC score	0.105560 (rank : 96)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	173	Target Neighborhood Hits	161	Shared Neighborhood Hits	64
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

ZN313_MOUSE
NC score	0.104079 (rank : 97)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	173	Target Neighborhood Hits	273	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

PCGF4_MOUSE
NC score	0.103915 (rank : 98)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	63
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

CBL_HUMAN
NC score	0.102551 (rank : 99)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	173	Target Neighborhood Hits	353	Shared Neighborhood Hits	64
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
NC score	0.100491 (rank : 100)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	173	Target Neighborhood Hits	426	Shared Neighborhood Hits	67
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

MDM4_MOUSE
NC score	0.098663 (rank : 101)	θ value	0.0961366 (rank : 59)
Query Neighborhood Hits	173	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

CBLB_HUMAN
NC score	0.096521 (rank : 102)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	173	Target Neighborhood Hits	261	Shared Neighborhood Hits	62
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CKAP2_HUMAN
NC score	0.095917 (rank : 103)	θ value	0.00869519 (rank : 43)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

CBLB_MOUSE
NC score	0.095295 (rank : 104)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	173	Target Neighborhood Hits	277	Shared Neighborhood Hits	62
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

ZN294_MOUSE
NC score	0.094522 (rank : 105)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	173	Target Neighborhood Hits	81	Shared Neighborhood Hits	41
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

ZN294_HUMAN
NC score	0.094078 (rank : 106)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

RNF5_HUMAN
NC score	0.093702 (rank : 107)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	173	Target Neighborhood Hits	206	Shared Neighborhood Hits	60
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.093047 (rank : 108)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	173	Target Neighborhood Hits	206	Shared Neighborhood Hits	59
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

MGRN1_HUMAN
NC score	0.081862 (rank : 109)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	173	Target Neighborhood Hits	192	Shared Neighborhood Hits	39
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
NC score	0.081008 (rank : 110)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	173	Target Neighborhood Hits	149	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RN125_HUMAN
NC score	0.080595 (rank : 111)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	173	Target Neighborhood Hits	230	Shared Neighborhood Hits	49
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI39_HUMAN
NC score	0.079896 (rank : 112)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	173	Target Neighborhood Hits	693	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RING1_HUMAN
NC score	0.079760 (rank : 113)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	173	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.079015 (rank : 114)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	173	Target Neighborhood Hits	220	Shared Neighborhood Hits	51
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI39_MOUSE
NC score	0.078728 (rank : 115)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	173	Target Neighborhood Hits	691	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

BFAR_MOUSE
NC score	0.078068 (rank : 116)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	173	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI35_HUMAN
NC score	0.077261 (rank : 117)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	173	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI59_MOUSE
NC score	0.076345 (rank : 118)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	173	Target Neighborhood Hits	292	Shared Neighborhood Hits	62
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI35_MOUSE
NC score	0.074906 (rank : 119)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	173	Target Neighborhood Hits	465	Shared Neighborhood Hits	57
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

RN166_HUMAN
NC score	0.073259 (rank : 120)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	173	Target Neighborhood Hits	240	Shared Neighborhood Hits	55
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.072771 (rank : 121)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	173	Target Neighborhood Hits	248	Shared Neighborhood Hits	55
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI59_HUMAN
NC score	0.072396 (rank : 122)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

RING2_MOUSE
NC score	0.071964 (rank : 123)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	173	Target Neighborhood Hits	199	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.071877 (rank : 124)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	173	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

BFAR_HUMAN
NC score	0.070812 (rank : 125)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	173	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

FILA_HUMAN
NC score	0.069980 (rank : 126)	θ value	0.0252991 (rank : 51)
Query Neighborhood Hits	173	Target Neighborhood Hits	685	Shared Neighborhood Hits	37
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

RFWD2_MOUSE
NC score	0.068936 (rank : 127)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	173	Target Neighborhood Hits	535	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

PZRN3_MOUSE
NC score	0.068158 (rank : 128)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	67
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.068003 (rank : 129)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	173	Target Neighborhood Hits	461	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRI37_HUMAN
NC score	0.067478 (rank : 130)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

SRRM2_HUMAN
NC score	0.067076 (rank : 131)	θ value	0.0563607 (rank : 55)
Query Neighborhood Hits	173	Target Neighborhood Hits	1296	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RFWD2_HUMAN
NC score	0.067015 (rank : 132)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	173	Target Neighborhood Hits	518	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

TRI56_HUMAN
NC score	0.065598 (rank : 133)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	173	Target Neighborhood Hits	339	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI50_MOUSE
NC score	0.064813 (rank : 134)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	173	Target Neighborhood Hits	326	Shared Neighborhood Hits	60
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI37_MOUSE
NC score	0.063929 (rank : 135)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	173	Target Neighborhood Hits	316	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI25_MOUSE
NC score	0.063388 (rank : 136)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	173	Target Neighborhood Hits	446	Shared Neighborhood Hits	59
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI40_HUMAN
NC score	0.062930 (rank : 137)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	173	Target Neighborhood Hits	279	Shared Neighborhood Hits	51
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TTC16_HUMAN
NC score	0.057582 (rank : 138)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	173	Target Neighborhood Hits	417	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

LNX2_MOUSE
NC score	0.057515 (rank : 139)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	173	Target Neighborhood Hits	407	Shared Neighborhood Hits	67
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX2_HUMAN
NC score	0.057096 (rank : 140)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	173	Target Neighborhood Hits	389	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RN146_HUMAN
NC score	0.057089 (rank : 141)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN125_MOUSE
NC score	0.056135 (rank : 142)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	173	Target Neighborhood Hits	220	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

SFR16_HUMAN
NC score	0.056006 (rank : 143)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	173	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N2M8, O96026, Q6UW71, Q96DX2	Gene names	SFRS16, SWAP2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2).

RN152_HUMAN
NC score	0.055580 (rank : 144)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	173	Target Neighborhood Hits	107	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
NC score	0.055311 (rank : 145)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	173	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN146_MOUSE
NC score	0.055121 (rank : 146)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	173	Target Neighborhood Hits	161	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN168_MOUSE
NC score	0.054609 (rank : 147)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	173	Target Neighborhood Hits	440	Shared Neighborhood Hits	50
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI31_HUMAN
NC score	0.054524 (rank : 148)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	173	Target Neighborhood Hits	299	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI50_HUMAN
NC score	0.054232 (rank : 149)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	173	Target Neighborhood Hits	294	Shared Neighborhood Hits	49
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI26_MOUSE
NC score	0.054115 (rank : 150)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	173	Target Neighborhood Hits	339	Shared Neighborhood Hits	59
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

MKRN3_MOUSE
NC score	0.053612 (rank : 151)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	173	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

TRI26_HUMAN
NC score	0.053577 (rank : 152)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	173	Target Neighborhood Hits	335	Shared Neighborhood Hits	56
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

RO52_HUMAN
NC score	0.053379 (rank : 153)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	173	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TARA_HUMAN
NC score	0.053047 (rank : 154)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	173	Target Neighborhood Hits	1626	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PCGF6_MOUSE
NC score	0.052686 (rank : 155)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI73_HUMAN
NC score	0.052577 (rank : 156)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	173	Target Neighborhood Hits	258	Shared Neighborhood Hits	44
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRIM8_HUMAN
NC score	0.052436 (rank : 157)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	173	Target Neighborhood Hits	650	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

SRRM2_MOUSE
NC score	0.052372 (rank : 158)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	173	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TRI25_HUMAN
NC score	0.052292 (rank : 159)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	173	Target Neighborhood Hits	472	Shared Neighborhood Hits	56
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

PCGF6_HUMAN
NC score	0.052084 (rank : 160)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	173	Target Neighborhood Hits	178	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RN168_HUMAN
NC score	0.050975 (rank : 161)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	173	Target Neighborhood Hits	370	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

PZRN4_HUMAN
NC score	0.050898 (rank : 162)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	173	Target Neighborhood Hits	438	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRI12_MOUSE
NC score	0.050841 (rank : 163)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	173	Target Neighborhood Hits	387	Shared Neighborhood Hits	51
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRIM8_MOUSE
NC score	0.050612 (rank : 164)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	173	Target Neighborhood Hits	674	Shared Neighborhood Hits	47
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI29_HUMAN
NC score	0.050595 (rank : 165)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	173	Target Neighborhood Hits	273	Shared Neighborhood Hits	21
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

AMFR1_HUMAN
NC score	0.050426 (rank : 166)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	173	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P26442	Gene names	AMFR
Domain Architecture	No domain graphic available
Description	Autocrine motility factor receptor precursor, isoform 1 (AMF receptor).

TRI32_HUMAN
NC score	0.050425 (rank : 167)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	173	Target Neighborhood Hits	264	Shared Neighborhood Hits	42
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI74_HUMAN
NC score	0.050289 (rank : 168)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	173	Target Neighborhood Hits	249	Shared Neighborhood Hits	38
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

DSPP_HUMAN
NC score	0.050181 (rank : 169)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	173	Target Neighborhood Hits	645	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LNX1_MOUSE
NC score	0.050040 (rank : 170)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	173	Target Neighborhood Hits	377	Shared Neighborhood Hits	53
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

HORN_MOUSE
NC score	0.048379 (rank : 171)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	173	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

SFR16_MOUSE
NC score	0.046363 (rank : 172)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	173	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CFC7, Q8CFC8, Q9Z2N3	Gene names	Sfrs16, Clasp, Swap2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2) (Clk4-associating SR-related protein).

TRI29_MOUSE
NC score	0.044661 (rank : 173)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	173	Target Neighborhood Hits	306	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

SFRS4_MOUSE
NC score	0.044175 (rank : 174)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	173	Target Neighborhood Hits	406	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SFRIP_HUMAN
NC score	0.038484 (rank : 175)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	173	Target Neighborhood Hits	530	Shared Neighborhood Hits	26
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

EYA1_HUMAN
NC score	0.037540 (rank : 176)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	173	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q99502	Gene names	EYA1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

SFRS4_HUMAN
NC score	0.036675 (rank : 177)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	173	Target Neighborhood Hits	384	Shared Neighborhood Hits	24
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

DMP1_HUMAN
NC score	0.034042 (rank : 178)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	173	Target Neighborhood Hits	491	Shared Neighborhood Hits	20
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TGON2_HUMAN
NC score	0.033824 (rank : 179)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	173	Target Neighborhood Hits	1037	Shared Neighborhood Hits	40
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TARA_MOUSE
NC score	0.032291 (rank : 180)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	173	Target Neighborhood Hits	1133	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MUC13_MOUSE
NC score	0.031240 (rank : 181)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

CHD5_HUMAN
NC score	0.030891 (rank : 182)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	173	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
NC score	0.030758 (rank : 183)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	173	Target Neighborhood Hits	397	Shared Neighborhood Hits	23
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

EYA1_MOUSE
NC score	0.030142 (rank : 184)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	173	Target Neighborhood Hits	108	Shared Neighborhood Hits	9
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

NPBL_MOUSE
NC score	0.028476 (rank : 185)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	173	Target Neighborhood Hits	1041	Shared Neighborhood Hits	34
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

LEO1_MOUSE
NC score	0.027873 (rank : 186)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	173	Target Neighborhood Hits	946	Shared Neighborhood Hits	21
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

VRK3_HUMAN
NC score	0.027343 (rank : 187)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	173	Target Neighborhood Hits	349	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

IWS1_HUMAN
NC score	0.026801 (rank : 188)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	173	Target Neighborhood Hits	1241	Shared Neighborhood Hits	30
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SMAD4_HUMAN
NC score	0.026246 (rank : 189)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

UHRF1_MOUSE
NC score	0.024870 (rank : 190)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	173	Target Neighborhood Hits	278	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

TCF20_MOUSE
NC score	0.024197 (rank : 191)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	173	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

RIMS1_HUMAN
NC score	0.024189 (rank : 192)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	173	Target Neighborhood Hits	437	Shared Neighborhood Hits	19
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

TCF20_HUMAN
NC score	0.020849 (rank : 193)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	173	Target Neighborhood Hits	323	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

NSMA2_MOUSE
NC score	0.020270 (rank : 194)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	173	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

PDZD2_HUMAN
NC score	0.019528 (rank : 195)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	173	Target Neighborhood Hits	772	Shared Neighborhood Hits	22
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

NKTR_HUMAN
NC score	0.019325 (rank : 196)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	173	Target Neighborhood Hits	658	Shared Neighborhood Hits	28
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

COHA1_HUMAN
NC score	0.018258 (rank : 197)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	173	Target Neighborhood Hits	400	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

K0082_MOUSE
NC score	0.016967 (rank : 198)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	173	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBC3, Q3U3G5, Q3U7Y9, Q6A0D5, Q8C7V0	Gene names	Kiaa0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

GRAM3_MOUSE
NC score	0.016378 (rank : 199)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	173	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEM6	Gene names	Gramd3
Domain Architecture	No domain graphic available
Description	GRAM domain-containing protein 3.

NU214_HUMAN
NC score	0.015743 (rank : 200)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	173	Target Neighborhood Hits	657	Shared Neighborhood Hits	16
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

GP124_MOUSE
NC score	0.015666 (rank : 201)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	173	Target Neighborhood Hits	423	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

LIPB2_MOUSE
NC score	0.014061 (rank : 202)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	173	Target Neighborhood Hits	570	Shared Neighborhood Hits	9
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

YETS2_HUMAN
NC score	0.013651 (rank : 203)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

NMDE2_HUMAN
NC score	0.013106 (rank : 204)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	173	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
NC score	0.013103 (rank : 205)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	173	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

GRIN1_HUMAN
NC score	0.012888 (rank : 206)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	173	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PGCA_MOUSE
NC score	0.011816 (rank : 207)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	173	Target Neighborhood Hits	643	Shared Neighborhood Hits	17
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

CAC1B_MOUSE
NC score	0.011266 (rank : 208)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	173	Target Neighborhood Hits	351	Shared Neighborhood Hits	11
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

LONM_HUMAN
NC score	0.011240 (rank : 209)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

DOCK3_HUMAN
NC score	0.010848 (rank : 210)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

DKK2_MOUSE
NC score	0.010679 (rank : 211)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	173	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYZ8	Gene names	Dkk2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (mDkk-2).

SON_HUMAN
NC score	0.010396 (rank : 212)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	173	Target Neighborhood Hits	1568	Shared Neighborhood Hits	25
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

AT10B_HUMAN
NC score	0.010205 (rank : 213)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	173	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O94823, Q9H725	Gene names	ATP10B, ATPVB, KIAA0715
Domain Architecture
Description	Probable phospholipid-transporting ATPase VB (EC 3.6.3.1).

DOCK3_MOUSE
NC score	0.009779 (rank : 214)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	173	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

INVS_HUMAN
NC score	0.007133 (rank : 215)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	173	Target Neighborhood Hits	455	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

WDR22_MOUSE
NC score	0.006606 (rank : 216)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	173	Target Neighborhood Hits	302	Shared Neighborhood Hits	8
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

SUHW1_HUMAN
NC score	0.006310 (rank : 217)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	173	Target Neighborhood Hits	648	Shared Neighborhood Hits	8
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

LRC50_MOUSE
NC score	0.006190 (rank : 218)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	173	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2H9, Q9CVS9	Gene names	Lrrc50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

RECQ4_HUMAN
NC score	0.005199 (rank : 219)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	173	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

E41L2_HUMAN
NC score	0.004072 (rank : 220)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	173	Target Neighborhood Hits	287	Shared Neighborhood Hits	8
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

REST_MOUSE
NC score	0.004043 (rank : 221)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	173	Target Neighborhood Hits	1506	Shared Neighborhood Hits	25
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ZN297_MOUSE
NC score	0.003838 (rank : 222)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	173	Target Neighborhood Hits	816	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0G7	Gene names	Znf297, Bing1, Zfp297
Domain Architecture
Description	Zinc finger protein 297 (BING1 protein).

ANRA2_MOUSE
NC score	0.002398 (rank : 223)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	173	Target Neighborhood Hits	287	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ZBT37_HUMAN
NC score	-0.000819 (rank : 224)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	173	Target Neighborhood Hits	815	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TC79, Q5TC80, Q96M87, Q9BQ88	Gene names	ZBTB37
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 37.

ZN507_HUMAN
NC score	-0.001259 (rank : 225)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	173	Target Neighborhood Hits	739	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

M3K15_HUMAN
NC score	-0.001848 (rank : 226)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	173	Target Neighborhood Hits	914	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

GP101_MOUSE
NC score	-0.003161 (rank : 227)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	173	Target Neighborhood Hits	916	Shared Neighborhood Hits	3
SwissProt Accessions	Q80T62, Q3UUI9	Gene names	Gpr101
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 101.

M3K4_MOUSE
NC score	-0.003302 (rank : 228)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	173	Target Neighborhood Hits	924	Shared Neighborhood Hits	7
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

MYO3B_HUMAN
NC score	-0.003953 (rank : 229)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	173	Target Neighborhood Hits	923	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXR4, Q8IX64, Q8IX65, Q8IX66, Q8IX67, Q8IX68	Gene names	MYO3B
Domain Architecture
Description	Myosin IIIB (EC 2.7.11.1).

ZKSC1_HUMAN
NC score	-0.004023 (rank : 230)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	173	Target Neighborhood Hits	949	Shared Neighborhood Hits	16
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

E2AK2_HUMAN
NC score	-0.004464 (rank : 231)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	173	Target Neighborhood Hits	856	Shared Neighborhood Hits	6
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).