Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : RNF12_MOUSE

For an explanation of this page, click here

RNF12_MOUSE
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RNF12_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	159	Target Neighborhood Hits	159	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF12_HUMAN
θ value	1.90044e-183 (rank : 2)	NC score	0.973585 (rank : 2)
Query Neighborhood Hits	159	Target Neighborhood Hits	173	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF6_HUMAN
θ value	1.09934e-114 (rank : 3)	NC score	0.947183 (rank : 3)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF13_HUMAN
θ value	7.58209e-15 (rank : 4)	NC score	0.712174 (rank : 8)
Query Neighborhood Hits	159	Target Neighborhood Hits	147	Shared Neighborhood Hits	86
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	7.58209e-15 (rank : 5)	NC score	0.715288 (rank : 7)
Query Neighborhood Hits	159	Target Neighborhood Hits	164	Shared Neighborhood Hits	88
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RN167_HUMAN
θ value	2.88119e-14 (rank : 6)	NC score	0.721945 (rank : 4)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	2.88119e-14 (rank : 7)	NC score	0.719307 (rank : 5)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	90
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF38_HUMAN
θ value	8.38298e-14 (rank : 8)	NC score	0.717062 (rank : 6)
Query Neighborhood Hits	159	Target Neighborhood Hits	155	Shared Neighborhood Hits	99
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF38_MOUSE
θ value	4.16044e-13 (rank : 9)	NC score	0.711779 (rank : 9)
Query Neighborhood Hits	159	Target Neighborhood Hits	153	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

GOLI_MOUSE
θ value	1.33837e-11 (rank : 10)	NC score	0.688374 (rank : 13)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	90
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
θ value	1.74796e-11 (rank : 11)	NC score	0.684944 (rank : 14)
Query Neighborhood Hits	159	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RN126_HUMAN
θ value	3.64472e-09 (rank : 12)	NC score	0.651731 (rank : 19)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN165_HUMAN
θ value	3.64472e-09 (rank : 13)	NC score	0.704137 (rank : 12)
Query Neighborhood Hits	159	Target Neighborhood Hits	151	Shared Neighborhood Hits	100
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

ZN364_MOUSE
θ value	3.64472e-09 (rank : 14)	NC score	0.650016 (rank : 21)
Query Neighborhood Hits	159	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RN126_MOUSE
θ value	4.76016e-09 (rank : 15)	NC score	0.658464 (rank : 17)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	99
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

ZN364_HUMAN
θ value	1.06045e-08 (rank : 16)	NC score	0.651375 (rank : 20)
Query Neighborhood Hits	159	Target Neighborhood Hits	140	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

PJA1_HUMAN
θ value	2.36244e-08 (rank : 17)	NC score	0.604519 (rank : 25)
Query Neighborhood Hits	159	Target Neighborhood Hits	159	Shared Neighborhood Hits	90
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	2.36244e-08 (rank : 18)	NC score	0.614435 (rank : 24)
Query Neighborhood Hits	159	Target Neighborhood Hits	145	Shared Neighborhood Hits	90
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RNF11_HUMAN
θ value	2.36244e-08 (rank : 19)	NC score	0.711561 (rank : 10)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	2.36244e-08 (rank : 20)	NC score	0.709587 (rank : 11)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RN122_HUMAN
θ value	3.41135e-07 (rank : 21)	NC score	0.663480 (rank : 16)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	7.59969e-07 (rank : 22)	NC score	0.664564 (rank : 15)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN133_HUMAN
θ value	7.59969e-07 (rank : 23)	NC score	0.652947 (rank : 18)
Query Neighborhood Hits	159	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RNF24_HUMAN
θ value	4.92598e-06 (rank : 24)	NC score	0.637050 (rank : 23)
Query Neighborhood Hits	159	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	4.92598e-06 (rank : 25)	NC score	0.638536 (rank : 22)
Query Neighborhood Hits	159	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

DZIP3_HUMAN
θ value	6.43352e-06 (rank : 26)	NC score	0.439750 (rank : 36)
Query Neighborhood Hits	159	Target Neighborhood Hits	399	Shared Neighborhood Hits	92
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	1.09739e-05 (rank : 27)	NC score	0.443899 (rank : 35)
Query Neighborhood Hits	159	Target Neighborhood Hits	414	Shared Neighborhood Hits	94
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

ZSWM2_MOUSE
θ value	1.87187e-05 (rank : 28)	NC score	0.466446 (rank : 32)
Query Neighborhood Hits	159	Target Neighborhood Hits	132	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

AMFR_MOUSE
θ value	5.44631e-05 (rank : 29)	NC score	0.484593 (rank : 28)
Query Neighborhood Hits	159	Target Neighborhood Hits	208	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
θ value	7.1131e-05 (rank : 30)	NC score	0.481817 (rank : 29)
Query Neighborhood Hits	159	Target Neighborhood Hits	219	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RN139_HUMAN
θ value	7.1131e-05 (rank : 31)	NC score	0.510095 (rank : 26)
Query Neighborhood Hits	159	Target Neighborhood Hits	130	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
θ value	7.1131e-05 (rank : 32)	NC score	0.502888 (rank : 27)
Query Neighborhood Hits	159	Target Neighborhood Hits	131	Shared Neighborhood Hits	92
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN103_HUMAN
θ value	0.000158464 (rank : 33)	NC score	0.471557 (rank : 31)
Query Neighborhood Hits	159	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	0.000158464 (rank : 34)	NC score	0.473857 (rank : 30)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

ZSWM2_HUMAN
θ value	0.000270298 (rank : 35)	NC score	0.433661 (rank : 37)
Query Neighborhood Hits	159	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RNF32_HUMAN
θ value	0.000602161 (rank : 36)	NC score	0.370988 (rank : 40)
Query Neighborhood Hits	159	Target Neighborhood Hits	133	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	0.000602161 (rank : 37)	NC score	0.362060 (rank : 41)
Query Neighborhood Hits	159	Target Neighborhood Hits	129	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RN141_MOUSE
θ value	0.000786445 (rank : 38)	NC score	0.455561 (rank : 33)
Query Neighborhood Hits	159	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

BRAP_HUMAN
θ value	0.00175202 (rank : 39)	NC score	0.253295 (rank : 60)
Query Neighborhood Hits	159	Target Neighborhood Hits	560	Shared Neighborhood Hits	78
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	0.00175202 (rank : 40)	NC score	0.284237 (rank : 50)
Query Neighborhood Hits	159	Target Neighborhood Hits	409	Shared Neighborhood Hits	76
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

MYCB2_MOUSE
θ value	0.00298849 (rank : 41)	NC score	0.163685 (rank : 76)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RN141_HUMAN
θ value	0.00298849 (rank : 42)	NC score	0.447481 (rank : 34)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

MYCB2_HUMAN
θ value	0.00390308 (rank : 43)	NC score	0.162532 (rank : 77)
Query Neighborhood Hits	159	Target Neighborhood Hits	390	Shared Neighborhood Hits	45
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RNF8_HUMAN
θ value	0.00390308 (rank : 44)	NC score	0.255296 (rank : 59)
Query Neighborhood Hits	159	Target Neighborhood Hits	622	Shared Neighborhood Hits	94
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TTC3_HUMAN
θ value	0.00509761 (rank : 45)	NC score	0.263873 (rank : 56)
Query Neighborhood Hits	159	Target Neighborhood Hits	664	Shared Neighborhood Hits	82
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

RNF8_MOUSE
θ value	0.00665767 (rank : 46)	NC score	0.264808 (rank : 55)
Query Neighborhood Hits	159	Target Neighborhood Hits	618	Shared Neighborhood Hits	95
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI65_MOUSE
θ value	0.00869519 (rank : 47)	NC score	0.165607 (rank : 75)
Query Neighborhood Hits	159	Target Neighborhood Hits	340	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RBX1_HUMAN
θ value	0.0113563 (rank : 48)	NC score	0.311646 (rank : 46)
Query Neighborhood Hits	159	Target Neighborhood Hits	51	Shared Neighborhood Hits	47
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
θ value	0.0113563 (rank : 49)	NC score	0.311646 (rank : 47)
Query Neighborhood Hits	159	Target Neighborhood Hits	51	Shared Neighborhood Hits	47
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

ZN363_HUMAN
θ value	0.0113563 (rank : 50)	NC score	0.352577 (rank : 43)
Query Neighborhood Hits	159	Target Neighborhood Hits	162	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	0.0113563 (rank : 51)	NC score	0.361456 (rank : 42)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	55
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

RAPSN_HUMAN
θ value	0.0148317 (rank : 52)	NC score	0.253204 (rank : 61)
Query Neighborhood Hits	159	Target Neighborhood Hits	84	Shared Neighborhood Hits	48
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
θ value	0.0148317 (rank : 53)	NC score	0.250810 (rank : 62)
Query Neighborhood Hits	159	Target Neighborhood Hits	92	Shared Neighborhood Hits	49
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

TARA_HUMAN
θ value	0.0148317 (rank : 54)	NC score	0.046642 (rank : 173)
Query Neighborhood Hits	159	Target Neighborhood Hits	1626	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DSPP_HUMAN
θ value	0.0330416 (rank : 55)	NC score	0.056097 (rank : 157)
Query Neighborhood Hits	159	Target Neighborhood Hits	645	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CHFR_MOUSE
θ value	0.0431538 (rank : 56)	NC score	0.275136 (rank : 52)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	85
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CKAP2_HUMAN
θ value	0.0431538 (rank : 57)	NC score	0.083098 (rank : 120)
Query Neighborhood Hits	159	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

RNF25_HUMAN
θ value	0.0431538 (rank : 58)	NC score	0.207321 (rank : 64)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RNF25_MOUSE
θ value	0.0431538 (rank : 59)	NC score	0.221792 (rank : 63)
Query Neighborhood Hits	159	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

APC11_MOUSE
θ value	0.0563607 (rank : 60)	NC score	0.317653 (rank : 45)
Query Neighborhood Hits	159	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

TRAIP_HUMAN
θ value	0.0563607 (rank : 61)	NC score	0.185488 (rank : 69)
Query Neighborhood Hits	159	Target Neighborhood Hits	780	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	0.0563607 (rank : 62)	NC score	0.185229 (rank : 70)
Query Neighborhood Hits	159	Target Neighborhood Hits	745	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

MDM4_HUMAN
θ value	0.0736092 (rank : 63)	NC score	0.097586 (rank : 106)
Query Neighborhood Hits	159	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

RBX2_HUMAN
θ value	0.0736092 (rank : 64)	NC score	0.384242 (rank : 39)
Query Neighborhood Hits	159	Target Neighborhood Hits	83	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	0.0736092 (rank : 65)	NC score	0.384883 (rank : 38)
Query Neighborhood Hits	159	Target Neighborhood Hits	82	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RN175_HUMAN
θ value	0.0736092 (rank : 66)	NC score	0.344545 (rank : 44)
Query Neighborhood Hits	159	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

APC11_HUMAN
θ value	0.0961366 (rank : 67)	NC score	0.305126 (rank : 49)
Query Neighborhood Hits	159	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

CM007_MOUSE
θ value	0.0961366 (rank : 68)	NC score	0.202721 (rank : 65)
Query Neighborhood Hits	159	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DTX3_HUMAN
θ value	0.0961366 (rank : 69)	NC score	0.176338 (rank : 71)
Query Neighborhood Hits	159	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	0.0961366 (rank : 70)	NC score	0.173807 (rank : 72)
Query Neighborhood Hits	159	Target Neighborhood Hits	202	Shared Neighborhood Hits	71
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

IWS1_HUMAN
θ value	0.0961366 (rank : 71)	NC score	0.033322 (rank : 179)
Query Neighborhood Hits	159	Target Neighborhood Hits	1241	Shared Neighborhood Hits	27
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PEX10_HUMAN
θ value	0.0961366 (rank : 72)	NC score	0.308297 (rank : 48)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	97
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

CM007_HUMAN
θ value	0.125558 (rank : 73)	NC score	0.190379 (rank : 66)
Query Neighborhood Hits	159	Target Neighborhood Hits	422	Shared Neighborhood Hits	78
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRI39_HUMAN
θ value	0.125558 (rank : 74)	NC score	0.085385 (rank : 113)
Query Neighborhood Hits	159	Target Neighborhood Hits	693	Shared Neighborhood Hits	83
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.125558 (rank : 75)	NC score	0.084428 (rank : 116)
Query Neighborhood Hits	159	Target Neighborhood Hits	691	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM2_HUMAN
θ value	0.125558 (rank : 76)	NC score	0.166527 (rank : 73)
Query Neighborhood Hits	159	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.125558 (rank : 77)	NC score	0.166144 (rank : 74)
Query Neighborhood Hits	159	Target Neighborhood Hits	331	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

IL4RA_MOUSE
θ value	0.21417 (rank : 78)	NC score	0.039406 (rank : 174)
Query Neighborhood Hits	159	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

YTDC1_HUMAN
θ value	0.21417 (rank : 79)	NC score	0.038857 (rank : 175)
Query Neighborhood Hits	159	Target Neighborhood Hits	458	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

CHFR_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.271168 (rank : 53)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	84
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TOPRS_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.269599 (rank : 54)
Query Neighborhood Hits	159	Target Neighborhood Hits	286	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	0.279714 (rank : 82)	NC score	0.276507 (rank : 51)
Query Neighborhood Hits	159	Target Neighborhood Hits	263	Shared Neighborhood Hits	95
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CAC1B_MOUSE
θ value	0.365318 (rank : 83)	NC score	0.016026 (rank : 193)
Query Neighborhood Hits	159	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

RNF4_HUMAN
θ value	0.365318 (rank : 84)	NC score	0.261619 (rank : 57)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	83
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	0.365318 (rank : 85)	NC score	0.259096 (rank : 58)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI13_MOUSE
θ value	0.365318 (rank : 86)	NC score	0.125292 (rank : 90)
Query Neighborhood Hits	159	Target Neighborhood Hits	282	Shared Neighborhood Hits	77
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRIM3_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.148842 (rank : 83)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	78
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

MNAB_MOUSE
θ value	0.47712 (rank : 88)	NC score	0.037483 (rank : 177)
Query Neighborhood Hits	159	Target Neighborhood Hits	231	Shared Neighborhood Hits	24
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RIMS1_HUMAN
θ value	0.47712 (rank : 89)	NC score	0.025293 (rank : 182)
Query Neighborhood Hits	159	Target Neighborhood Hits	437	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

TRI13_HUMAN
θ value	0.47712 (rank : 90)	NC score	0.121957 (rank : 92)
Query Neighborhood Hits	159	Target Neighborhood Hits	274	Shared Neighborhood Hits	77
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRIM3_MOUSE
θ value	0.47712 (rank : 91)	NC score	0.144191 (rank : 84)
Query Neighborhood Hits	159	Target Neighborhood Hits	351	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

CK5P2_HUMAN
θ value	0.62314 (rank : 92)	NC score	0.017481 (rank : 192)
Query Neighborhood Hits	159	Target Neighborhood Hits	1433	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

DMN_HUMAN
θ value	0.62314 (rank : 93)	NC score	0.013756 (rank : 197)
Query Neighborhood Hits	159	Target Neighborhood Hits	690	Shared Neighborhood Hits	10
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

MDM4_MOUSE
θ value	0.62314 (rank : 94)	NC score	0.082778 (rank : 121)
Query Neighborhood Hits	159	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

RNF41_HUMAN
θ value	0.62314 (rank : 95)	NC score	0.187467 (rank : 67)
Query Neighborhood Hits	159	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.62314 (rank : 96)	NC score	0.187451 (rank : 68)
Query Neighborhood Hits	159	Target Neighborhood Hits	224	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

CBLC_MOUSE
θ value	0.813845 (rank : 97)	NC score	0.149777 (rank : 81)
Query Neighborhood Hits	159	Target Neighborhood Hits	186	Shared Neighborhood Hits	66
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

VPS11_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.120004 (rank : 95)
Query Neighborhood Hits	159	Target Neighborhood Hits	86	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

VPS11_MOUSE
θ value	1.06291 (rank : 99)	NC score	0.121086 (rank : 93)
Query Neighborhood Hits	159	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

DTX3L_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.151173 (rank : 80)
Query Neighborhood Hits	159	Target Neighborhood Hits	187	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

ROCK1_MOUSE
θ value	1.38821 (rank : 101)	NC score	0.000366 (rank : 214)
Query Neighborhood Hits	159	Target Neighborhood Hits	2126	Shared Neighborhood Hits	26
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SOX11_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.010518 (rank : 203)
Query Neighborhood Hits	159	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

TRHY_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.019512 (rank : 190)
Query Neighborhood Hits	159	Target Neighborhood Hits	1385	Shared Neighborhood Hits	23
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ZN294_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.106530 (rank : 103)
Query Neighborhood Hits	159	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

ZN294_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.107011 (rank : 102)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

TRI65_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.154055 (rank : 78)
Query Neighborhood Hits	159	Target Neighborhood Hits	330	Shared Neighborhood Hits	83
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ZN313_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.134871 (rank : 86)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

EPN2_HUMAN
θ value	2.36792 (rank : 108)	NC score	0.014313 (rank : 196)
Query Neighborhood Hits	159	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

EVL_MOUSE
θ value	2.36792 (rank : 109)	NC score	0.020093 (rank : 189)
Query Neighborhood Hits	159	Target Neighborhood Hits	203	Shared Neighborhood Hits	8
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

OXR1_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.020432 (rank : 187)
Query Neighborhood Hits	159	Target Neighborhood Hits	516	Shared Neighborhood Hits	13
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

TBX3_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.008428 (rank : 207)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

K0460_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.020219 (rank : 188)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

PKHG1_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.011685 (rank : 201)
Query Neighborhood Hits	159	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

RN185_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.153036 (rank : 79)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	74
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.149380 (rank : 82)
Query Neighborhood Hits	159	Target Neighborhood Hits	211	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

SRRM2_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.037553 (rank : 176)
Query Neighborhood Hits	159	Target Neighborhood Hits	1470	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BAALC_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.022820 (rank : 184)
Query Neighborhood Hits	159	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHV1, Q8VBS8, Q9CYS9	Gene names	Baalc
Domain Architecture	No domain graphic available
Description	Brain and acute leukemia cytoplasmic protein.

CE005_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.011249 (rank : 202)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

FANCL_MOUSE
θ value	4.03905 (rank : 119)	NC score	0.022874 (rank : 183)
Query Neighborhood Hits	159	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CR14, Q3TGY2, Q9D017	Gene names	Fancl, Phf9, Pog
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein FANCL (EC 6.3.2.-) (Fanconi anemia group L protein homolog) (Proliferation of germ cells protein).

NMDE2_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.012424 (rank : 199)
Query Neighborhood Hits	159	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
θ value	4.03905 (rank : 121)	NC score	0.012420 (rank : 200)
Query Neighborhood Hits	159	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

PKP4_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.007839 (rank : 208)
Query Neighborhood Hits	159	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

RFWD2_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.076324 (rank : 126)
Query Neighborhood Hits	159	Target Neighborhood Hits	535	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

SFRS4_MOUSE
θ value	4.03905 (rank : 124)	NC score	0.027607 (rank : 181)
Query Neighborhood Hits	159	Target Neighborhood Hits	406	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SPEG_HUMAN
θ value	4.03905 (rank : 125)	NC score	-0.001214 (rank : 215)
Query Neighborhood Hits	159	Target Neighborhood Hits	1762	Shared Neighborhood Hits	15
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

STON2_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.014825 (rank : 195)
Query Neighborhood Hits	159	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

TRI25_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.068471 (rank : 135)
Query Neighborhood Hits	159	Target Neighborhood Hits	446	Shared Neighborhood Hits	61
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI37_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.075082 (rank : 127)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	45
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI50_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.065948 (rank : 136)
Query Neighborhood Hits	159	Target Neighborhood Hits	326	Shared Neighborhood Hits	63
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

XRN1_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.013481 (rank : 198)
Query Neighborhood Hits	159	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

ZN313_MOUSE
θ value	4.03905 (rank : 131)	NC score	0.122428 (rank : 91)
Query Neighborhood Hits	159	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

BFAR_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.091009 (rank : 108)
Query Neighborhood Hits	159	Target Neighborhood Hits	232	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRWD1_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.006979 (rank : 211)
Query Neighborhood Hits	159	Target Neighborhood Hits	448	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

EVL_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.018277 (rank : 191)
Query Neighborhood Hits	159	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FA54A_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.015674 (rank : 194)
Query Neighborhood Hits	159	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P444, Q5JWR7, Q6ZUE8, Q7L3U6, Q9BZ39	Gene names	FAM54A, DUFD1
Domain Architecture	No domain graphic available
Description	Protein FAM54A (DUF729 domain-containing protein 1).

GDF5_MOUSE
θ value	5.27518 (rank : 136)	NC score	0.004364 (rank : 213)
Query Neighborhood Hits	159	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

LMBL3_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.008801 (rank : 206)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

LNX2_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.061770 (rank : 142)
Query Neighborhood Hits	159	Target Neighborhood Hits	407	Shared Neighborhood Hits	72
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PCGF2_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.129684 (rank : 88)
Query Neighborhood Hits	159	Target Neighborhood Hits	222	Shared Neighborhood Hits	66
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.129308 (rank : 89)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	64
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

RAD18_MOUSE
θ value	5.27518 (rank : 141)	NC score	0.135357 (rank : 85)
Query Neighborhood Hits	159	Target Neighborhood Hits	230	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RFWD2_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.075038 (rank : 128)
Query Neighborhood Hits	159	Target Neighborhood Hits	518	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

SRCH_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.020475 (rank : 186)
Query Neighborhood Hits	159	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

SRRM2_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.054366 (rank : 160)
Query Neighborhood Hits	159	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TOIP2_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.020881 (rank : 185)
Query Neighborhood Hits	159	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

TOM1_HUMAN
θ value	5.27518 (rank : 146)	NC score	0.009500 (rank : 205)
Query Neighborhood Hits	159	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

CBLC_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.120277 (rank : 94)
Query Neighborhood Hits	159	Target Neighborhood Hits	173	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CE005_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.009767 (rank : 204)
Query Neighborhood Hits	159	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

GRIP1_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.005836 (rank : 212)
Query Neighborhood Hits	159	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

IBP3_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.007149 (rank : 210)
Query Neighborhood Hits	159	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

BRWD1_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.007681 (rank : 209)
Query Neighborhood Hits	159	Target Neighborhood Hits	478	Shared Neighborhood Hits	10
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

MAST4_HUMAN
θ value	8.99809 (rank : 152)	NC score	-0.003144 (rank : 216)
Query Neighborhood Hits	159	Target Neighborhood Hits	1804	Shared Neighborhood Hits	21
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MKRN3_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.058588 (rank : 148)
Query Neighborhood Hits	159	Target Neighborhood Hits	137	Shared Neighborhood Hits	44
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

RAD18_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.133953 (rank : 87)
Query Neighborhood Hits	159	Target Neighborhood Hits	284	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

SALL4_HUMAN
θ value	8.99809 (rank : 155)	NC score	-0.004475 (rank : 218)
Query Neighborhood Hits	159	Target Neighborhood Hits	799	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJQ4	Gene names	SALL4
Domain Architecture
Description	Sal-like protein 4 (Zinc finger protein SALL4).

SFRIP_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.031794 (rank : 180)
Query Neighborhood Hits	159	Target Neighborhood Hits	530	Shared Neighborhood Hits	21
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SUHW2_HUMAN
θ value	8.99809 (rank : 157)	NC score	-0.003776 (rank : 217)
Query Neighborhood Hits	159	Target Neighborhood Hits	683	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YH2	Gene names	SUHW2, ZNF632
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 2 (5'OY11.1) (Zinc finger protein 632).

TRI59_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.086927 (rank : 111)
Query Neighborhood Hits	159	Target Neighborhood Hits	292	Shared Neighborhood Hits	65
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TTC16_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.036972 (rank : 178)
Query Neighborhood Hits	159	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

BFAR_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.083474 (rank : 119)
Query Neighborhood Hits	159	Target Neighborhood Hits	222	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BRCA1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.050758 (rank : 170)
Query Neighborhood Hits	159	Target Neighborhood Hits	381	Shared Neighborhood Hits	55
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

CBLB_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.103788 (rank : 104)
Query Neighborhood Hits	159	Target Neighborhood Hits	261	Shared Neighborhood Hits	64
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.103078 (rank : 105)
Query Neighborhood Hits	159	Target Neighborhood Hits	277	Shared Neighborhood Hits	65
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBL_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.110339 (rank : 100)
Query Neighborhood Hits	159	Target Neighborhood Hits	353	Shared Neighborhood Hits	70
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.107417 (rank : 101)
Query Neighborhood Hits	159	Target Neighborhood Hits	426	Shared Neighborhood Hits	69
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

LNX1_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.050447 (rank : 171)
Query Neighborhood Hits	159	Target Neighborhood Hits	379	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.052234 (rank : 167)
Query Neighborhood Hits	159	Target Neighborhood Hits	377	Shared Neighborhood Hits	58
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.062241 (rank : 140)
Query Neighborhood Hits	159	Target Neighborhood Hits	389	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MGRN1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.084892 (rank : 115)
Query Neighborhood Hits	159	Target Neighborhood Hits	192	Shared Neighborhood Hits	44
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.084148 (rank : 117)
Query Neighborhood Hits	159	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

PCGF4_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.114458 (rank : 96)
Query Neighborhood Hits	159	Target Neighborhood Hits	161	Shared Neighborhood Hits	63
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.112771 (rank : 97)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF6_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.058139 (rank : 149)
Query Neighborhood Hits	159	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.059052 (rank : 147)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PZRN3_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.074156 (rank : 130)
Query Neighborhood Hits	159	Target Neighborhood Hits	461	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.073853 (rank : 131)
Query Neighborhood Hits	159	Target Neighborhood Hits	447	Shared Neighborhood Hits	74
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.056495 (rank : 153)
Query Neighborhood Hits	159	Target Neighborhood Hits	438	Shared Neighborhood Hits	68
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RING1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.086795 (rank : 112)
Query Neighborhood Hits	159	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.085116 (rank : 114)
Query Neighborhood Hits	159	Target Neighborhood Hits	220	Shared Neighborhood Hits	52
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.079433 (rank : 125)
Query Neighborhood Hits	159	Target Neighborhood Hits	201	Shared Neighborhood Hits	54
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.079515 (rank : 124)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN125_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.097344 (rank : 107)
Query Neighborhood Hits	159	Target Neighborhood Hits	230	Shared Neighborhood Hits	56
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.074215 (rank : 129)
Query Neighborhood Hits	159	Target Neighborhood Hits	220	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN146_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.065626 (rank : 137)
Query Neighborhood Hits	159	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.062726 (rank : 139)
Query Neighborhood Hits	159	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN152_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.053390 (rank : 166)
Query Neighborhood Hits	159	Target Neighborhood Hits	107	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.053799 (rank : 164)
Query Neighborhood Hits	159	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN166_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.088178 (rank : 109)
Query Neighborhood Hits	159	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.087893 (rank : 110)
Query Neighborhood Hits	159	Target Neighborhood Hits	248	Shared Neighborhood Hits	59
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.061192 (rank : 143)
Query Neighborhood Hits	159	Target Neighborhood Hits	370	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.064298 (rank : 138)
Query Neighborhood Hits	159	Target Neighborhood Hits	440	Shared Neighborhood Hits	53
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN183_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.050848 (rank : 169)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	30
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF37_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.054364 (rank : 161)
Query Neighborhood Hits	159	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

RNF5_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.112047 (rank : 98)
Query Neighborhood Hits	159	Target Neighborhood Hits	206	Shared Neighborhood Hits	64
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.111333 (rank : 99)
Query Neighborhood Hits	159	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RO52_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.054672 (rank : 159)
Query Neighborhood Hits	159	Target Neighborhood Hits	419	Shared Neighborhood Hits	67
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI10_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.054068 (rank : 163)
Query Neighborhood Hits	159	Target Neighborhood Hits	315	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI12_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.053470 (rank : 165)
Query Neighborhood Hits	159	Target Neighborhood Hits	387	Shared Neighborhood Hits	52
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI25_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.059245 (rank : 146)
Query Neighborhood Hits	159	Target Neighborhood Hits	472	Shared Neighborhood Hits	60
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI26_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.060394 (rank : 145)
Query Neighborhood Hits	159	Target Neighborhood Hits	335	Shared Neighborhood Hits	61
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.061842 (rank : 141)
Query Neighborhood Hits	159	Target Neighborhood Hits	339	Shared Neighborhood Hits	64
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI31_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.060611 (rank : 144)
Query Neighborhood Hits	159	Target Neighborhood Hits	299	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.056750 (rank : 152)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.055624 (rank : 158)
Query Neighborhood Hits	159	Target Neighborhood Hits	271	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI35_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.083844 (rank : 118)
Query Neighborhood Hits	159	Target Neighborhood Hits	382	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.081159 (rank : 123)
Query Neighborhood Hits	159	Target Neighborhood Hits	465	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI37_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.070555 (rank : 134)
Query Neighborhood Hits	159	Target Neighborhood Hits	316	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI40_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.071995 (rank : 132)
Query Neighborhood Hits	159	Target Neighborhood Hits	279	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI50_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.056484 (rank : 154)
Query Neighborhood Hits	159	Target Neighborhood Hits	294	Shared Neighborhood Hits	52
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI56_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.070575 (rank : 133)
Query Neighborhood Hits	159	Target Neighborhood Hits	339	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.056258 (rank : 156)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI59_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.082542 (rank : 122)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI60_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.050097 (rank : 172)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	57
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI73_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.056991 (rank : 151)
Query Neighborhood Hits	159	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.054330 (rank : 162)
Query Neighborhood Hits	159	Target Neighborhood Hits	249	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM5_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.052225 (rank : 168)
Query Neighborhood Hits	159	Target Neighborhood Hits	424	Shared Neighborhood Hits	57
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM8_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.057582 (rank : 150)
Query Neighborhood Hits	159	Target Neighborhood Hits	650	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.056259 (rank : 155)
Query Neighborhood Hits	159	Target Neighborhood Hits	674	Shared Neighborhood Hits	50
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

Hits sorted by NC score

RNF12_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	159	Target Neighborhood Hits	159	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF12_HUMAN
NC score	0.973585 (rank : 2)	θ value	1.90044e-183 (rank : 2)
Query Neighborhood Hits	159	Target Neighborhood Hits	173	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF6_HUMAN
NC score	0.947183 (rank : 3)	θ value	1.09934e-114 (rank : 3)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RN167_HUMAN
NC score	0.721945 (rank : 4)	θ value	2.88119e-14 (rank : 6)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
NC score	0.719307 (rank : 5)	θ value	2.88119e-14 (rank : 7)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	90
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF38_HUMAN
NC score	0.717062 (rank : 6)	θ value	8.38298e-14 (rank : 8)
Query Neighborhood Hits	159	Target Neighborhood Hits	155	Shared Neighborhood Hits	99
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF13_MOUSE
NC score	0.715288 (rank : 7)	θ value	7.58209e-15 (rank : 5)
Query Neighborhood Hits	159	Target Neighborhood Hits	164	Shared Neighborhood Hits	88
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF13_HUMAN
NC score	0.712174 (rank : 8)	θ value	7.58209e-15 (rank : 4)
Query Neighborhood Hits	159	Target Neighborhood Hits	147	Shared Neighborhood Hits	86
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF38_MOUSE
NC score	0.711779 (rank : 9)	θ value	4.16044e-13 (rank : 9)
Query Neighborhood Hits	159	Target Neighborhood Hits	153	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF11_HUMAN
NC score	0.711561 (rank : 10)	θ value	2.36244e-08 (rank : 19)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
NC score	0.709587 (rank : 11)	θ value	2.36244e-08 (rank : 20)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RN165_HUMAN
NC score	0.704137 (rank : 12)	θ value	3.64472e-09 (rank : 13)
Query Neighborhood Hits	159	Target Neighborhood Hits	151	Shared Neighborhood Hits	100
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

GOLI_MOUSE
NC score	0.688374 (rank : 13)	θ value	1.33837e-11 (rank : 10)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	90
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
NC score	0.684944 (rank : 14)	θ value	1.74796e-11 (rank : 11)
Query Neighborhood Hits	159	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RN122_MOUSE
NC score	0.664564 (rank : 15)	θ value	7.59969e-07 (rank : 22)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_HUMAN
NC score	0.663480 (rank : 16)	θ value	3.41135e-07 (rank : 21)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN126_MOUSE
NC score	0.658464 (rank : 17)	θ value	4.76016e-09 (rank : 15)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	99
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN133_HUMAN
NC score	0.652947 (rank : 18)	θ value	7.59969e-07 (rank : 23)
Query Neighborhood Hits	159	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RN126_HUMAN
NC score	0.651731 (rank : 19)	θ value	3.64472e-09 (rank : 12)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

ZN364_HUMAN
NC score	0.651375 (rank : 20)	θ value	1.06045e-08 (rank : 16)
Query Neighborhood Hits	159	Target Neighborhood Hits	140	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
NC score	0.650016 (rank : 21)	θ value	3.64472e-09 (rank : 14)
Query Neighborhood Hits	159	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RNF24_MOUSE
NC score	0.638536 (rank : 22)	θ value	4.92598e-06 (rank : 25)
Query Neighborhood Hits	159	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.637050 (rank : 23)	θ value	4.92598e-06 (rank : 24)
Query Neighborhood Hits	159	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

PJA1_MOUSE
NC score	0.614435 (rank : 24)	θ value	2.36244e-08 (rank : 18)
Query Neighborhood Hits	159	Target Neighborhood Hits	145	Shared Neighborhood Hits	90
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PJA1_HUMAN
NC score	0.604519 (rank : 25)	θ value	2.36244e-08 (rank : 17)
Query Neighborhood Hits	159	Target Neighborhood Hits	159	Shared Neighborhood Hits	90
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RN139_HUMAN
NC score	0.510095 (rank : 26)	θ value	7.1131e-05 (rank : 31)
Query Neighborhood Hits	159	Target Neighborhood Hits	130	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
NC score	0.502888 (rank : 27)	θ value	7.1131e-05 (rank : 32)
Query Neighborhood Hits	159	Target Neighborhood Hits	131	Shared Neighborhood Hits	92
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

AMFR_MOUSE
NC score	0.484593 (rank : 28)	θ value	5.44631e-05 (rank : 29)
Query Neighborhood Hits	159	Target Neighborhood Hits	208	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.481817 (rank : 29)	θ value	7.1131e-05 (rank : 30)
Query Neighborhood Hits	159	Target Neighborhood Hits	219	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RN103_MOUSE
NC score	0.473857 (rank : 30)	θ value	0.000158464 (rank : 34)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN103_HUMAN
NC score	0.471557 (rank : 31)	θ value	0.000158464 (rank : 33)
Query Neighborhood Hits	159	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

ZSWM2_MOUSE
NC score	0.466446 (rank : 32)	θ value	1.87187e-05 (rank : 28)
Query Neighborhood Hits	159	Target Neighborhood Hits	132	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN141_MOUSE
NC score	0.455561 (rank : 33)	θ value	0.000786445 (rank : 38)
Query Neighborhood Hits	159	Target Neighborhood Hits	200	Shared Neighborhood Hits	84
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.447481 (rank : 34)	θ value	0.00298849 (rank : 42)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

DZIP3_MOUSE
NC score	0.443899 (rank : 35)	θ value	1.09739e-05 (rank : 27)
Query Neighborhood Hits	159	Target Neighborhood Hits	414	Shared Neighborhood Hits	94
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DZIP3_HUMAN
NC score	0.439750 (rank : 36)	θ value	6.43352e-06 (rank : 26)
Query Neighborhood Hits	159	Target Neighborhood Hits	399	Shared Neighborhood Hits	92
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

ZSWM2_HUMAN
NC score	0.433661 (rank : 37)	θ value	0.000270298 (rank : 35)
Query Neighborhood Hits	159	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RBX2_MOUSE
NC score	0.384883 (rank : 38)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	159	Target Neighborhood Hits	82	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RBX2_HUMAN
NC score	0.384242 (rank : 39)	θ value	0.0736092 (rank : 64)
Query Neighborhood Hits	159	Target Neighborhood Hits	83	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RNF32_HUMAN
NC score	0.370988 (rank : 40)	θ value	0.000602161 (rank : 36)
Query Neighborhood Hits	159	Target Neighborhood Hits	133	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
NC score	0.362060 (rank : 41)	θ value	0.000602161 (rank : 37)
Query Neighborhood Hits	159	Target Neighborhood Hits	129	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

ZN363_MOUSE
NC score	0.361456 (rank : 42)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	55
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN363_HUMAN
NC score	0.352577 (rank : 43)	θ value	0.0113563 (rank : 50)
Query Neighborhood Hits	159	Target Neighborhood Hits	162	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

RN175_HUMAN
NC score	0.344545 (rank : 44)	θ value	0.0736092 (rank : 66)
Query Neighborhood Hits	159	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

APC11_MOUSE
NC score	0.317653 (rank : 45)	θ value	0.0563607 (rank : 60)
Query Neighborhood Hits	159	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

RBX1_HUMAN
NC score	0.311646 (rank : 46)	θ value	0.0113563 (rank : 48)
Query Neighborhood Hits	159	Target Neighborhood Hits	51	Shared Neighborhood Hits	47
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
NC score	0.311646 (rank : 47)	θ value	0.0113563 (rank : 49)
Query Neighborhood Hits	159	Target Neighborhood Hits	51	Shared Neighborhood Hits	47
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

PEX10_HUMAN
NC score	0.308297 (rank : 48)	θ value	0.0961366 (rank : 72)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	97
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

APC11_HUMAN
NC score	0.305126 (rank : 49)	θ value	0.0961366 (rank : 67)
Query Neighborhood Hits	159	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

BRAP_MOUSE
NC score	0.284237 (rank : 50)	θ value	0.00175202 (rank : 40)
Query Neighborhood Hits	159	Target Neighborhood Hits	409	Shared Neighborhood Hits	76
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

TOPRS_MOUSE
NC score	0.276507 (rank : 51)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	159	Target Neighborhood Hits	263	Shared Neighborhood Hits	95
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CHFR_MOUSE
NC score	0.275136 (rank : 52)	θ value	0.0431538 (rank : 56)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	85
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_HUMAN
NC score	0.271168 (rank : 53)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	84
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TOPRS_HUMAN
NC score	0.269599 (rank : 54)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	159	Target Neighborhood Hits	286	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RNF8_MOUSE
NC score	0.264808 (rank : 55)	θ value	0.00665767 (rank : 46)
Query Neighborhood Hits	159	Target Neighborhood Hits	618	Shared Neighborhood Hits	95
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TTC3_HUMAN
NC score	0.263873 (rank : 56)	θ value	0.00509761 (rank : 45)
Query Neighborhood Hits	159	Target Neighborhood Hits	664	Shared Neighborhood Hits	82
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

RNF4_HUMAN
NC score	0.261619 (rank : 57)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	83
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.259096 (rank : 58)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF8_HUMAN
NC score	0.255296 (rank : 59)	θ value	0.00390308 (rank : 44)
Query Neighborhood Hits	159	Target Neighborhood Hits	622	Shared Neighborhood Hits	94
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

BRAP_HUMAN
NC score	0.253295 (rank : 60)	θ value	0.00175202 (rank : 39)
Query Neighborhood Hits	159	Target Neighborhood Hits	560	Shared Neighborhood Hits	78
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RAPSN_HUMAN
NC score	0.253204 (rank : 61)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	159	Target Neighborhood Hits	84	Shared Neighborhood Hits	48
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
NC score	0.250810 (rank : 62)	θ value	0.0148317 (rank : 53)
Query Neighborhood Hits	159	Target Neighborhood Hits	92	Shared Neighborhood Hits	49
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RNF25_MOUSE
NC score	0.221792 (rank : 63)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	159	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RNF25_HUMAN
NC score	0.207321 (rank : 64)	θ value	0.0431538 (rank : 58)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

CM007_MOUSE
NC score	0.202721 (rank : 65)	θ value	0.0961366 (rank : 68)
Query Neighborhood Hits	159	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CM007_HUMAN
NC score	0.190379 (rank : 66)	θ value	0.125558 (rank : 73)
Query Neighborhood Hits	159	Target Neighborhood Hits	422	Shared Neighborhood Hits	78
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

RNF41_HUMAN
NC score	0.187467 (rank : 67)	θ value	0.62314 (rank : 95)
Query Neighborhood Hits	159	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.187451 (rank : 68)	θ value	0.62314 (rank : 96)
Query Neighborhood Hits	159	Target Neighborhood Hits	224	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRAIP_HUMAN
NC score	0.185488 (rank : 69)	θ value	0.0563607 (rank : 61)
Query Neighborhood Hits	159	Target Neighborhood Hits	780	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
NC score	0.185229 (rank : 70)	θ value	0.0563607 (rank : 62)
Query Neighborhood Hits	159	Target Neighborhood Hits	745	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

DTX3_HUMAN
NC score	0.176338 (rank : 71)	θ value	0.0961366 (rank : 69)
Query Neighborhood Hits	159	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
NC score	0.173807 (rank : 72)	θ value	0.0961366 (rank : 70)
Query Neighborhood Hits	159	Target Neighborhood Hits	202	Shared Neighborhood Hits	71
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TRIM2_HUMAN
NC score	0.166527 (rank : 73)	θ value	0.125558 (rank : 76)
Query Neighborhood Hits	159	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.166144 (rank : 74)	θ value	0.125558 (rank : 77)
Query Neighborhood Hits	159	Target Neighborhood Hits	331	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI65_MOUSE
NC score	0.165607 (rank : 75)	θ value	0.00869519 (rank : 47)
Query Neighborhood Hits	159	Target Neighborhood Hits	340	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

MYCB2_MOUSE
NC score	0.163685 (rank : 76)	θ value	0.00298849 (rank : 41)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_HUMAN
NC score	0.162532 (rank : 77)	θ value	0.00390308 (rank : 43)
Query Neighborhood Hits	159	Target Neighborhood Hits	390	Shared Neighborhood Hits	45
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TRI65_HUMAN
NC score	0.154055 (rank : 78)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	159	Target Neighborhood Hits	330	Shared Neighborhood Hits	83
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RN185_HUMAN
NC score	0.153036 (rank : 79)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	74
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

DTX3L_HUMAN
NC score	0.151173 (rank : 80)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	159	Target Neighborhood Hits	187	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

CBLC_MOUSE
NC score	0.149777 (rank : 81)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	159	Target Neighborhood Hits	186	Shared Neighborhood Hits	66
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RN185_MOUSE
NC score	0.149380 (rank : 82)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	159	Target Neighborhood Hits	211	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRIM3_HUMAN
NC score	0.148842 (rank : 83)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	78
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
NC score	0.144191 (rank : 84)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	159	Target Neighborhood Hits	351	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

RAD18_MOUSE
NC score	0.135357 (rank : 85)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	159	Target Neighborhood Hits	230	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

ZN313_HUMAN
NC score	0.134871 (rank : 86)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RAD18_HUMAN
NC score	0.133953 (rank : 87)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	159	Target Neighborhood Hits	284	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

PCGF2_HUMAN
NC score	0.129684 (rank : 88)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	159	Target Neighborhood Hits	222	Shared Neighborhood Hits	66
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.129308 (rank : 89)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	64
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TRI13_MOUSE
NC score	0.125292 (rank : 90)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	159	Target Neighborhood Hits	282	Shared Neighborhood Hits	77
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

ZN313_MOUSE
NC score	0.122428 (rank : 91)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	159	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRI13_HUMAN
NC score	0.121957 (rank : 92)	θ value	0.47712 (rank : 90)
Query Neighborhood Hits	159	Target Neighborhood Hits	274	Shared Neighborhood Hits	77
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

VPS11_MOUSE
NC score	0.121086 (rank : 93)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	159	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

CBLC_HUMAN
NC score	0.120277 (rank : 94)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	159	Target Neighborhood Hits	173	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

VPS11_HUMAN
NC score	0.120004 (rank : 95)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	159	Target Neighborhood Hits	86	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

PCGF4_HUMAN
NC score	0.114458 (rank : 96)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	159	Target Neighborhood Hits	161	Shared Neighborhood Hits	63
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.112771 (rank : 97)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RNF5_HUMAN
NC score	0.112047 (rank : 98)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	159	Target Neighborhood Hits	206	Shared Neighborhood Hits	64
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.111333 (rank : 99)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	159	Target Neighborhood Hits	206	Shared Neighborhood Hits	63
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

CBL_HUMAN
NC score	0.110339 (rank : 100)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	159	Target Neighborhood Hits	353	Shared Neighborhood Hits	70
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
NC score	0.107417 (rank : 101)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	159	Target Neighborhood Hits	426	Shared Neighborhood Hits	69
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

ZN294_MOUSE
NC score	0.107011 (rank : 102)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

ZN294_HUMAN
NC score	0.106530 (rank : 103)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	159	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

CBLB_HUMAN
NC score	0.103788 (rank : 104)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	159	Target Neighborhood Hits	261	Shared Neighborhood Hits	64
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
NC score	0.103078 (rank : 105)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	159	Target Neighborhood Hits	277	Shared Neighborhood Hits	65
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

MDM4_HUMAN
NC score	0.097586 (rank : 106)	θ value	0.0736092 (rank : 63)
Query Neighborhood Hits	159	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

RN125_HUMAN
NC score	0.097344 (rank : 107)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	159	Target Neighborhood Hits	230	Shared Neighborhood Hits	56
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

BFAR_MOUSE
NC score	0.091009 (rank : 108)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	159	Target Neighborhood Hits	232	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RN166_HUMAN
NC score	0.088178 (rank : 109)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	159	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.087893 (rank : 110)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	159	Target Neighborhood Hits	248	Shared Neighborhood Hits	59
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI59_MOUSE
NC score	0.086927 (rank : 111)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	159	Target Neighborhood Hits	292	Shared Neighborhood Hits	65
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

RING1_HUMAN
NC score	0.086795 (rank : 112)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	159	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

TRI39_HUMAN
NC score	0.085385 (rank : 113)	θ value	0.125558 (rank : 74)
Query Neighborhood Hits	159	Target Neighborhood Hits	693	Shared Neighborhood Hits	83
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RING1_MOUSE
NC score	0.085116 (rank : 114)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	159	Target Neighborhood Hits	220	Shared Neighborhood Hits	52
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

MGRN1_HUMAN
NC score	0.084892 (rank : 115)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	159	Target Neighborhood Hits	192	Shared Neighborhood Hits	44
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

TRI39_MOUSE
NC score	0.084428 (rank : 116)	θ value	0.125558 (rank : 75)
Query Neighborhood Hits	159	Target Neighborhood Hits	691	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

MGRN1_MOUSE
NC score	0.084148 (rank : 117)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	159	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

TRI35_HUMAN
NC score	0.083844 (rank : 118)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	159	Target Neighborhood Hits	382	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

BFAR_HUMAN
NC score	0.083474 (rank : 119)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	159	Target Neighborhood Hits	222	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

CKAP2_HUMAN
NC score	0.083098 (rank : 120)	θ value	0.0431538 (rank : 57)
Query Neighborhood Hits	159	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

MDM4_MOUSE
NC score	0.082778 (rank : 121)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	159	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

TRI59_HUMAN
NC score	0.082542 (rank : 122)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI35_MOUSE
NC score	0.081159 (rank : 123)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	159	Target Neighborhood Hits	465	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

RING2_MOUSE
NC score	0.079515 (rank : 124)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.079433 (rank : 125)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	159	Target Neighborhood Hits	201	Shared Neighborhood Hits	54
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RFWD2_MOUSE
NC score	0.076324 (rank : 126)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	159	Target Neighborhood Hits	535	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRI37_HUMAN
NC score	0.075082 (rank : 127)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	45
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

RFWD2_HUMAN
NC score	0.075038 (rank : 128)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	159	Target Neighborhood Hits	518	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RN125_MOUSE
NC score	0.074215 (rank : 129)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	159	Target Neighborhood Hits	220	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

PZRN3_HUMAN
NC score	0.074156 (rank : 130)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	159	Target Neighborhood Hits	461	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
NC score	0.073853 (rank : 131)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	159	Target Neighborhood Hits	447	Shared Neighborhood Hits	74
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRI40_HUMAN
NC score	0.071995 (rank : 132)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	159	Target Neighborhood Hits	279	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI56_HUMAN
NC score	0.070575 (rank : 133)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	159	Target Neighborhood Hits	339	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI37_MOUSE
NC score	0.070555 (rank : 134)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	159	Target Neighborhood Hits	316	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI25_MOUSE
NC score	0.068471 (rank : 135)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	159	Target Neighborhood Hits	446	Shared Neighborhood Hits	61
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI50_MOUSE
NC score	0.065948 (rank : 136)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	159	Target Neighborhood Hits	326	Shared Neighborhood Hits	63
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RN146_HUMAN
NC score	0.065626 (rank : 137)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	159	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN168_MOUSE
NC score	0.064298 (rank : 138)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	159	Target Neighborhood Hits	440	Shared Neighborhood Hits	53
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN146_MOUSE
NC score	0.062726 (rank : 139)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	159	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

LNX2_HUMAN
NC score	0.062241 (rank : 140)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	159	Target Neighborhood Hits	389	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TRI26_MOUSE
NC score	0.061842 (rank : 141)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	159	Target Neighborhood Hits	339	Shared Neighborhood Hits	64
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

LNX2_MOUSE
NC score	0.061770 (rank : 142)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	159	Target Neighborhood Hits	407	Shared Neighborhood Hits	72
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RN168_HUMAN
NC score	0.061192 (rank : 143)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	159	Target Neighborhood Hits	370	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI31_HUMAN
NC score	0.060611 (rank : 144)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	159	Target Neighborhood Hits	299	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI26_HUMAN
NC score	0.060394 (rank : 145)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	159	Target Neighborhood Hits	335	Shared Neighborhood Hits	61
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI25_HUMAN
NC score	0.059245 (rank : 146)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	159	Target Neighborhood Hits	472	Shared Neighborhood Hits	60
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

PCGF6_MOUSE
NC score	0.059052 (rank : 147)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	40
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

MKRN3_MOUSE
NC score	0.058588 (rank : 148)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	159	Target Neighborhood Hits	137	Shared Neighborhood Hits	44
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

PCGF6_HUMAN
NC score	0.058139 (rank : 149)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	159	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRIM8_HUMAN
NC score	0.057582 (rank : 150)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	159	Target Neighborhood Hits	650	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI73_HUMAN
NC score	0.056991 (rank : 151)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	159	Target Neighborhood Hits	258	Shared Neighborhood Hits	49
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI32_HUMAN
NC score	0.056750 (rank : 152)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

PZRN4_HUMAN
NC score	0.056495 (rank : 153)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	159	Target Neighborhood Hits	438	Shared Neighborhood Hits	68
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRI50_HUMAN
NC score	0.056484 (rank : 154)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	159	Target Neighborhood Hits	294	Shared Neighborhood Hits	52
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRIM8_MOUSE
NC score	0.056259 (rank : 155)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	159	Target Neighborhood Hits	674	Shared Neighborhood Hits	50
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI56_MOUSE
NC score	0.056258 (rank : 156)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

DSPP_HUMAN
NC score	0.056097 (rank : 157)	θ value	0.0330416 (rank : 55)
Query Neighborhood Hits	159	Target Neighborhood Hits	645	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TRI32_MOUSE
NC score	0.055624 (rank : 158)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	159	Target Neighborhood Hits	271	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

RO52_HUMAN
NC score	0.054672 (rank : 159)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	159	Target Neighborhood Hits	419	Shared Neighborhood Hits	67
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

SRRM2_HUMAN
NC score	0.054366 (rank : 160)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	159	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RNF37_MOUSE
NC score	0.054364 (rank : 161)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	159	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

TRI74_HUMAN
NC score	0.054330 (rank : 162)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	159	Target Neighborhood Hits	249	Shared Neighborhood Hits	43
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI10_HUMAN
NC score	0.054068 (rank : 163)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	159	Target Neighborhood Hits	315	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

RN152_MOUSE
NC score	0.053799 (rank : 164)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	159	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TRI12_MOUSE
NC score	0.053470 (rank : 165)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	159	Target Neighborhood Hits	387	Shared Neighborhood Hits	52
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

RN152_HUMAN
NC score	0.053390 (rank : 166)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	159	Target Neighborhood Hits	107	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

LNX1_MOUSE
NC score	0.052234 (rank : 167)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	159	Target Neighborhood Hits	377	Shared Neighborhood Hits	58
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRIM5_HUMAN
NC score	0.052225 (rank : 168)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	159	Target Neighborhood Hits	424	Shared Neighborhood Hits	57
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

RN183_HUMAN
NC score	0.050848 (rank : 169)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	30
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

BRCA1_HUMAN
NC score	0.050758 (rank : 170)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	159	Target Neighborhood Hits	381	Shared Neighborhood Hits	55
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

LNX1_HUMAN
NC score	0.050447 (rank : 171)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	159	Target Neighborhood Hits	379	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRI60_HUMAN
NC score	0.050097 (rank : 172)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	57
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TARA_HUMAN
NC score	0.046642 (rank : 173)	θ value	0.0148317 (rank : 54)
Query Neighborhood Hits	159	Target Neighborhood Hits	1626	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

IL4RA_MOUSE
NC score	0.039406 (rank : 174)	θ value	0.21417 (rank : 78)
Query Neighborhood Hits	159	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

YTDC1_HUMAN
NC score	0.038857 (rank : 175)	θ value	0.21417 (rank : 79)
Query Neighborhood Hits	159	Target Neighborhood Hits	458	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

SRRM2_MOUSE
NC score	0.037553 (rank : 176)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	159	Target Neighborhood Hits	1470	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MNAB_MOUSE
NC score	0.037483 (rank : 177)	θ value	0.47712 (rank : 88)
Query Neighborhood Hits	159	Target Neighborhood Hits	231	Shared Neighborhood Hits	24
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

TTC16_HUMAN
NC score	0.036972 (rank : 178)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	159	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

IWS1_HUMAN
NC score	0.033322 (rank : 179)	θ value	0.0961366 (rank : 71)
Query Neighborhood Hits	159	Target Neighborhood Hits	1241	Shared Neighborhood Hits	27
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SFRIP_HUMAN
NC score	0.031794 (rank : 180)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	159	Target Neighborhood Hits	530	Shared Neighborhood Hits	21
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SFRS4_MOUSE
NC score	0.027607 (rank : 181)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	159	Target Neighborhood Hits	406	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

RIMS1_HUMAN
NC score	0.025293 (rank : 182)	θ value	0.47712 (rank : 89)
Query Neighborhood Hits	159	Target Neighborhood Hits	437	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

FANCL_MOUSE
NC score	0.022874 (rank : 183)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	159	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CR14, Q3TGY2, Q9D017	Gene names	Fancl, Phf9, Pog
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein FANCL (EC 6.3.2.-) (Fanconi anemia group L protein homolog) (Proliferation of germ cells protein).

BAALC_MOUSE
NC score	0.022820 (rank : 184)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	159	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHV1, Q8VBS8, Q9CYS9	Gene names	Baalc
Domain Architecture	No domain graphic available
Description	Brain and acute leukemia cytoplasmic protein.

TOIP2_MOUSE
NC score	0.020881 (rank : 185)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	159	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

SRCH_HUMAN
NC score	0.020475 (rank : 186)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	159	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

OXR1_MOUSE
NC score	0.020432 (rank : 187)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	159	Target Neighborhood Hits	516	Shared Neighborhood Hits	13
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

K0460_HUMAN
NC score	0.020219 (rank : 188)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

EVL_MOUSE
NC score	0.020093 (rank : 189)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	159	Target Neighborhood Hits	203	Shared Neighborhood Hits	8
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

TRHY_HUMAN
NC score	0.019512 (rank : 190)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	159	Target Neighborhood Hits	1385	Shared Neighborhood Hits	23
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

EVL_HUMAN
NC score	0.018277 (rank : 191)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	159	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

CK5P2_HUMAN
NC score	0.017481 (rank : 192)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	159	Target Neighborhood Hits	1433	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CAC1B_MOUSE
NC score	0.016026 (rank : 193)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	159	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

FA54A_HUMAN
NC score	0.015674 (rank : 194)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	159	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P444, Q5JWR7, Q6ZUE8, Q7L3U6, Q9BZ39	Gene names	FAM54A, DUFD1
Domain Architecture	No domain graphic available
Description	Protein FAM54A (DUF729 domain-containing protein 1).

STON2_HUMAN
NC score	0.014825 (rank : 195)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	159	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

EPN2_HUMAN
NC score	0.014313 (rank : 196)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	159	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

DMN_HUMAN
NC score	0.013756 (rank : 197)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	159	Target Neighborhood Hits	690	Shared Neighborhood Hits	10
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

XRN1_HUMAN
NC score	0.013481 (rank : 198)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	159	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

NMDE2_HUMAN
NC score	0.012424 (rank : 199)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	159	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
NC score	0.012420 (rank : 200)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	159	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

PKHG1_HUMAN
NC score	0.011685 (rank : 201)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	159	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

CE005_HUMAN
NC score	0.011249 (rank : 202)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

SOX11_HUMAN
NC score	0.010518 (rank : 203)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	159	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

CE005_MOUSE
NC score	0.009767 (rank : 204)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	159	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

TOM1_HUMAN
NC score	0.009500 (rank : 205)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	159	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

LMBL3_MOUSE
NC score	0.008801 (rank : 206)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

TBX3_HUMAN
NC score	0.008428 (rank : 207)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

PKP4_MOUSE
NC score	0.007839 (rank : 208)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	159	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

BRWD1_MOUSE
NC score	0.007681 (rank : 209)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	159	Target Neighborhood Hits	478	Shared Neighborhood Hits	10
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

IBP3_MOUSE
NC score	0.007149 (rank : 210)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	159	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

BRWD1_HUMAN
NC score	0.006979 (rank : 211)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	159	Target Neighborhood Hits	448	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

GRIP1_HUMAN
NC score	0.005836 (rank : 212)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	159	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GDF5_MOUSE
NC score	0.004364 (rank : 213)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	159	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

ROCK1_MOUSE
NC score	0.000366 (rank : 214)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	159	Target Neighborhood Hits	2126	Shared Neighborhood Hits	26
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SPEG_HUMAN
NC score	-0.001214 (rank : 215)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	159	Target Neighborhood Hits	1762	Shared Neighborhood Hits	15
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MAST4_HUMAN
NC score	-0.003144 (rank : 216)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	159	Target Neighborhood Hits	1804	Shared Neighborhood Hits	21
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SUHW2_HUMAN
NC score	-0.003776 (rank : 217)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	159	Target Neighborhood Hits	683	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YH2	Gene names	SUHW2, ZNF632
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 2 (5'OY11.1) (Zinc finger protein 632).

SALL4_HUMAN
NC score	-0.004475 (rank : 218)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	159	Target Neighborhood Hits	799	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJQ4	Gene names	SALL4
Domain Architecture
Description	Sal-like protein 4 (Zinc finger protein SALL4).