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Network neighborhood for query Sequence : VPS11_HUMAN

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VPS11_HUMAN
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

VPS11_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

VPS11_MOUSE
θ value	0 (rank : 2)	NC score	0.999027 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	87	Shared Neighborhood Hits	83
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

VPS18_MOUSE
θ value	2.13673e-09 (rank : 3)	NC score	0.352665 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R307, Q8BGV6, Q8BZX6, Q8C126	Gene names	Vps18
Domain Architecture
Description	Vacuolar protein sorting-associated protein 18.

VPS18_HUMAN
θ value	6.21693e-09 (rank : 4)	NC score	0.346171 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P253, Q8TCG0, Q96DI3, Q9H268	Gene names	VPS18, KIAA1475
Domain Architecture
Description	Vacuolar protein sorting-associated protein 18 (hVPS18).

VPS41_HUMAN
θ value	3.19293e-05 (rank : 5)	NC score	0.245951 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	P49754, Q99851, Q99852	Gene names	VPS41
Domain Architecture
Description	Vacuolar protein sorting-associated protein 41 homolog (S53).

VPS41_MOUSE
θ value	0.000270298 (rank : 6)	NC score	0.232432 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

AMFR2_HUMAN
θ value	0.00175202 (rank : 7)	NC score	0.196789 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	0.00175202 (rank : 8)	NC score	0.198283 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	208	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TTC3_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.129437 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	664	Shared Neighborhood Hits	54
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

MIB1_MOUSE
θ value	0.0148317 (rank : 10)	NC score	0.056915 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	471	Shared Neighborhood Hits	27
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RNF32_MOUSE
θ value	0.0252991 (rank : 11)	NC score	0.177598 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	129	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

TOPRS_HUMAN
θ value	0.0330416 (rank : 12)	NC score	0.169129 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	286	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	0.0330416 (rank : 13)	NC score	0.171402 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	263	Shared Neighborhood Hits	52
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

MIB1_HUMAN
θ value	0.0563607 (rank : 14)	NC score	0.053315 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	470	Shared Neighborhood Hits	27
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

RNF8_MOUSE
θ value	0.0563607 (rank : 15)	NC score	0.135157 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	618	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

XPOT_HUMAN
θ value	0.0961366 (rank : 16)	NC score	0.103260 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O43592, O43784, Q8WUG2, Q9BVS7	Gene names	XPOT
Domain Architecture
Description	Exportin-T (tRNA exportin) (Exportin(tRNA)).

TRAF5_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.063775 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

CHFR_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.131531 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	255	Shared Neighborhood Hits	52
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

DZIP3_MOUSE
θ value	0.279714 (rank : 19)	NC score	0.124916 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	414	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

RNF32_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.152879 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	133	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

DZIP3_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.123577 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	399	Shared Neighborhood Hits	49
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RBP26_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.035772 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

ZN179_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.088941 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN363_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.122407 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	162	Shared Neighborhood Hits	27
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

RNF12_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.118972 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	173	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

BRAP_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.084115 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	0.813845 (rank : 27)	NC score	0.094360 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	409	Shared Neighborhood Hits	44
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CHFR_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.118319 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	264	Shared Neighborhood Hits	51
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RNF6_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.115263 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

ZN363_MOUSE
θ value	0.813845 (rank : 30)	NC score	0.118707 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

CDC5L_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.039061 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

CEP55_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.030528 (rank : 96)
Query Neighborhood Hits	86	Target Neighborhood Hits	693	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

DMD_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.019756 (rank : 98)
Query Neighborhood Hits	86	Target Neighborhood Hits	1135	Shared Neighborhood Hits	21
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

RN141_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.135303 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.135674 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	200	Shared Neighborhood Hits	50
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RNF12_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.120004 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	159	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

TRAF5_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.056807 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	355	Shared Neighborhood Hits	32
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI50_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.044871 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	326	Shared Neighborhood Hits	43
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

BFAR_MOUSE
θ value	1.38821 (rank : 39)	NC score	0.087233 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	232	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

PFD6_MOUSE
θ value	1.38821 (rank : 40)	NC score	0.074743 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q03958	Gene names	Pfdn6, H2-Ke2, Pfd6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

PI3R4_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.040853 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	534	Shared Neighborhood Hits	6
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

RN165_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.132507 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RNF8_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.103808 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	622	Shared Neighborhood Hits	61
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

IQGA1_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.035649 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

PEX10_HUMAN
θ value	1.81305 (rank : 45)	NC score	0.109360 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	255	Shared Neighborhood Hits	60
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN103_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.081884 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	153	Shared Neighborhood Hits	36
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RO52_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.038686 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	419	Shared Neighborhood Hits	53
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI10_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.037510 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	285	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI22_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.042525 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	396	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

GOGA3_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.018718 (rank : 99)
Query Neighborhood Hits	86	Target Neighborhood Hits	1317	Shared Neighborhood Hits	27
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

RNF38_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.105645 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

BFAR_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.076948 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	222	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

IQGA1_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.029472 (rank : 97)
Query Neighborhood Hits	86	Target Neighborhood Hits	250	Shared Neighborhood Hits	7
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

PI3R4_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.033164 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	535	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

RFWD2_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.051484 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	518	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RN126_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.096741 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RNF38_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.103721 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF41_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.079839 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	226	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.079887 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	224	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRAIP_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.049775 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	780	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.049159 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	745	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

DTX3_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.068394 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	202	Shared Neighborhood Hits	48
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

PCGF2_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.062277 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	222	Shared Neighborhood Hits	42
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.062432 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PFD6_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.053967 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	O15212	Gene names	PFDN6, HKE2, PFD6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

PJA1_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.092391 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	159	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.092452 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	145	Shared Neighborhood Hits	45
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

TRI12_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.042843 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	387	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

CCD46_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.010314 (rank : 104)
Query Neighborhood Hits	86	Target Neighborhood Hits	1405	Shared Neighborhood Hits	25
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

DTX3_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.065987 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RAD18_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.066817 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	284	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

SPTB2_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.007774 (rank : 106)
Query Neighborhood Hits	86	Target Neighborhood Hits	748	Shared Neighborhood Hits	11
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SYTL4_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.009661 (rank : 105)
Query Neighborhood Hits	86	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

WDFY2_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.016582 (rank : 101)
Query Neighborhood Hits	86	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

CCD21_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.012256 (rank : 103)
Query Neighborhood Hits	86	Target Neighborhood Hits	1228	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

ECM29_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.016878 (rank : 100)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

KIF5C_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.005121 (rank : 109)
Query Neighborhood Hits	86	Target Neighborhood Hits	974	Shared Neighborhood Hits	15
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MLL2_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.007559 (rank : 107)
Query Neighborhood Hits	86	Target Neighborhood Hits	1788	Shared Neighborhood Hits	14
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PCGF4_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.059249 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	161	Shared Neighborhood Hits	41
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.059371 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	163	Shared Neighborhood Hits	41
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RAD18_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.064894 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	230	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RFWD2_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.048226 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	535	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TAF5L_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.007556 (rank : 108)
Query Neighborhood Hits	86	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

TRIM5_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.037423 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	424	Shared Neighborhood Hits	44
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM6_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.031202 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	412	Shared Neighborhood Hits	43
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

WDFY2_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.014611 (rank : 102)
Query Neighborhood Hits	86	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

GOLI_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.065400 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	137	Shared Neighborhood Hits	40
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.065806 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

RBX2_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.051052 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	83	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.051176 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	82	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RN103_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.055687 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	143	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN122_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.072395 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	121	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.071804 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	121	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN126_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.075276 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN133_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.065621 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RN139_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.061253 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	130	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.059253 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RN167_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.062506 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.062866 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF11_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.068761 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.068444 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RNF13_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.059043 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	147	Shared Neighborhood Hits	36
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.057781 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	164	Shared Neighborhood Hits	36
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF24_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.072589 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	122	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.072693 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF4_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.064194 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	212	Shared Neighborhood Hits	53
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.065150 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	212	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

ZN364_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.070110 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.069332 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	140	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

Hits sorted by NC score

VPS11_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

VPS11_MOUSE
NC score	0.999027 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	87	Shared Neighborhood Hits	83
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

VPS18_MOUSE
NC score	0.352665 (rank : 3)	θ value	2.13673e-09 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R307, Q8BGV6, Q8BZX6, Q8C126	Gene names	Vps18
Domain Architecture
Description	Vacuolar protein sorting-associated protein 18.

VPS18_HUMAN
NC score	0.346171 (rank : 4)	θ value	6.21693e-09 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P253, Q8TCG0, Q96DI3, Q9H268	Gene names	VPS18, KIAA1475
Domain Architecture
Description	Vacuolar protein sorting-associated protein 18 (hVPS18).

VPS41_HUMAN
NC score	0.245951 (rank : 5)	θ value	3.19293e-05 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	P49754, Q99851, Q99852	Gene names	VPS41
Domain Architecture
Description	Vacuolar protein sorting-associated protein 41 homolog (S53).

VPS41_MOUSE
NC score	0.232432 (rank : 6)	θ value	0.000270298 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

AMFR_MOUSE
NC score	0.198283 (rank : 7)	θ value	0.00175202 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	208	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.196789 (rank : 8)	θ value	0.00175202 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	219	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RNF32_MOUSE
NC score	0.177598 (rank : 9)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	129	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

TOPRS_MOUSE
NC score	0.171402 (rank : 10)	θ value	0.0330416 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	263	Shared Neighborhood Hits	52
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_HUMAN
NC score	0.169129 (rank : 11)	θ value	0.0330416 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	286	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RNF32_HUMAN
NC score	0.152879 (rank : 12)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	133	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RN141_MOUSE
NC score	0.135674 (rank : 13)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	200	Shared Neighborhood Hits	50
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.135303 (rank : 14)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	199	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RNF8_MOUSE
NC score	0.135157 (rank : 15)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	618	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RN165_HUMAN
NC score	0.132507 (rank : 16)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	151	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

CHFR_HUMAN
NC score	0.131531 (rank : 17)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	255	Shared Neighborhood Hits	52
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TTC3_HUMAN
NC score	0.129437 (rank : 18)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	664	Shared Neighborhood Hits	54
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

DZIP3_MOUSE
NC score	0.124916 (rank : 19)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	414	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DZIP3_HUMAN
NC score	0.123577 (rank : 20)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	399	Shared Neighborhood Hits	49
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

ZN363_HUMAN
NC score	0.122407 (rank : 21)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	162	Shared Neighborhood Hits	27
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

RNF12_MOUSE
NC score	0.120004 (rank : 22)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	159	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF12_HUMAN
NC score	0.118972 (rank : 23)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	173	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

ZN363_MOUSE
NC score	0.118707 (rank : 24)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

CHFR_MOUSE
NC score	0.118319 (rank : 25)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	264	Shared Neighborhood Hits	51
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RNF6_HUMAN
NC score	0.115263 (rank : 26)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

PEX10_HUMAN
NC score	0.109360 (rank : 27)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	255	Shared Neighborhood Hits	60
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RNF38_HUMAN
NC score	0.105645 (rank : 28)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF8_HUMAN
NC score	0.103808 (rank : 29)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	622	Shared Neighborhood Hits	61
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF38_MOUSE
NC score	0.103721 (rank : 30)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

XPOT_HUMAN
NC score	0.103260 (rank : 31)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O43592, O43784, Q8WUG2, Q9BVS7	Gene names	XPOT
Domain Architecture
Description	Exportin-T (tRNA exportin) (Exportin(tRNA)).

RN126_MOUSE
NC score	0.096741 (rank : 32)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

BRAP_MOUSE
NC score	0.094360 (rank : 33)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	409	Shared Neighborhood Hits	44
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

PJA1_MOUSE
NC score	0.092452 (rank : 34)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	145	Shared Neighborhood Hits	45
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PJA1_HUMAN
NC score	0.092391 (rank : 35)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	159	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

ZN179_HUMAN
NC score	0.088941 (rank : 36)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

BFAR_MOUSE
NC score	0.087233 (rank : 37)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	232	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRAP_HUMAN
NC score	0.084115 (rank : 38)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RN103_HUMAN
NC score	0.081884 (rank : 39)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	153	Shared Neighborhood Hits	36
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RNF41_MOUSE
NC score	0.079887 (rank : 40)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	224	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.079839 (rank : 41)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	226	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

BFAR_HUMAN
NC score	0.076948 (rank : 42)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	222	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RN126_HUMAN
NC score	0.075276 (rank : 43)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

PFD6_MOUSE
NC score	0.074743 (rank : 44)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q03958	Gene names	Pfdn6, H2-Ke2, Pfd6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

RNF24_MOUSE
NC score	0.072693 (rank : 45)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	86	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.072589 (rank : 46)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	86	Target Neighborhood Hits	122	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RN122_HUMAN
NC score	0.072395 (rank : 47)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	121	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
NC score	0.071804 (rank : 48)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	121	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

ZN364_HUMAN
NC score	0.070110 (rank : 49)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	86	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
NC score	0.069332 (rank : 50)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	86	Target Neighborhood Hits	140	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RNF11_HUMAN
NC score	0.068761 (rank : 51)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	86	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
NC score	0.068444 (rank : 52)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	86	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

DTX3_MOUSE
NC score	0.068394 (rank : 53)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	202	Shared Neighborhood Hits	48
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RAD18_HUMAN
NC score	0.066817 (rank : 54)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	284	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

DTX3_HUMAN
NC score	0.065987 (rank : 55)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

GOLI_MOUSE
NC score	0.065806 (rank : 56)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

RN133_HUMAN
NC score	0.065621 (rank : 57)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

GOLI_HUMAN
NC score	0.065400 (rank : 58)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	137	Shared Neighborhood Hits	40
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RNF4_MOUSE
NC score	0.065150 (rank : 59)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	86	Target Neighborhood Hits	212	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RAD18_MOUSE
NC score	0.064894 (rank : 60)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	230	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RNF4_HUMAN
NC score	0.064194 (rank : 61)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	86	Target Neighborhood Hits	212	Shared Neighborhood Hits	53
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRAF5_HUMAN
NC score	0.063775 (rank : 62)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

RN167_MOUSE
NC score	0.062866 (rank : 63)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_HUMAN
NC score	0.062506 (rank : 64)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

PCGF2_MOUSE
NC score	0.062432 (rank : 65)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.062277 (rank : 66)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	222	Shared Neighborhood Hits	42
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

RN139_HUMAN
NC score	0.061253 (rank : 67)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	86	Target Neighborhood Hits	130	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

PCGF4_MOUSE
NC score	0.059371 (rank : 68)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	163	Shared Neighborhood Hits	41
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RN139_MOUSE
NC score	0.059253 (rank : 69)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	86	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

PCGF4_HUMAN
NC score	0.059249 (rank : 70)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	161	Shared Neighborhood Hits	41
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

RNF13_HUMAN
NC score	0.059043 (rank : 71)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	86	Target Neighborhood Hits	147	Shared Neighborhood Hits	36
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
NC score	0.057781 (rank : 72)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	86	Target Neighborhood Hits	164	Shared Neighborhood Hits	36
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

MIB1_MOUSE
NC score	0.056915 (rank : 73)	θ value	0.0148317 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	471	Shared Neighborhood Hits	27
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

TRAF5_MOUSE
NC score	0.056807 (rank : 74)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	355	Shared Neighborhood Hits	32
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

RN103_MOUSE
NC score	0.055687 (rank : 75)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	143	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

PFD6_HUMAN
NC score	0.053967 (rank : 76)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	O15212	Gene names	PFDN6, HKE2, PFD6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

MIB1_HUMAN
NC score	0.053315 (rank : 77)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	470	Shared Neighborhood Hits	27
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

RFWD2_HUMAN
NC score	0.051484 (rank : 78)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	518	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RBX2_MOUSE
NC score	0.051176 (rank : 79)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	82	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RBX2_HUMAN
NC score	0.051052 (rank : 80)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	83	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

TRAIP_HUMAN
NC score	0.049775 (rank : 81)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	780	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
NC score	0.049159 (rank : 82)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	745	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

RFWD2_MOUSE
NC score	0.048226 (rank : 83)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	535	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRI50_MOUSE
NC score	0.044871 (rank : 84)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	326	Shared Neighborhood Hits	43
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI12_MOUSE
NC score	0.042843 (rank : 85)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	387	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI22_HUMAN
NC score	0.042525 (rank : 86)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	396	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

PI3R4_HUMAN
NC score	0.040853 (rank : 87)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	534	Shared Neighborhood Hits	6
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

CDC5L_MOUSE
NC score	0.039061 (rank : 88)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

RO52_HUMAN
NC score	0.038686 (rank : 89)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	419	Shared Neighborhood Hits	53
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI10_MOUSE
NC score	0.037510 (rank : 90)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	285	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRIM5_HUMAN
NC score	0.037423 (rank : 91)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	424	Shared Neighborhood Hits	44
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

RBP26_HUMAN
NC score	0.035772 (rank : 92)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

IQGA1_MOUSE
NC score	0.035649 (rank : 93)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKF1	Gene names	Iqgap1
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1.

PI3R4_MOUSE
NC score	0.033164 (rank : 94)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	535	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

TRIM6_HUMAN
NC score	0.031202 (rank : 95)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	412	Shared Neighborhood Hits	43
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

CEP55_MOUSE
NC score	0.030528 (rank : 96)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	693	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

IQGA1_HUMAN
NC score	0.029472 (rank : 97)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	250	Shared Neighborhood Hits	7
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

DMD_HUMAN
NC score	0.019756 (rank : 98)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	1135	Shared Neighborhood Hits	21
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

GOGA3_HUMAN
NC score	0.018718 (rank : 99)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	1317	Shared Neighborhood Hits	27
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

ECM29_MOUSE
NC score	0.016878 (rank : 100)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

WDFY2_MOUSE
NC score	0.016582 (rank : 101)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY2_HUMAN
NC score	0.014611 (rank : 102)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

CCD21_HUMAN
NC score	0.012256 (rank : 103)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	1228	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD46_MOUSE
NC score	0.010314 (rank : 104)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	1405	Shared Neighborhood Hits	25
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

SYTL4_MOUSE
NC score	0.009661 (rank : 105)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SPTB2_HUMAN
NC score	0.007774 (rank : 106)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	748	Shared Neighborhood Hits	11
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

MLL2_HUMAN
NC score	0.007559 (rank : 107)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	1788	Shared Neighborhood Hits	14
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TAF5L_HUMAN
NC score	0.007556 (rank : 108)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

KIF5C_HUMAN
NC score	0.005121 (rank : 109)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	974	Shared Neighborhood Hits	15
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).