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Network neighborhood for query Sequence : PJA1_HUMAN

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PJA1_HUMAN
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PJA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	159	Target Neighborhood Hits	159	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	0 (rank : 2)	NC score	0.981463 (rank : 2)
Query Neighborhood Hits	159	Target Neighborhood Hits	145	Shared Neighborhood Hits	115
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RN126_MOUSE
θ value	8.95645e-16 (rank : 3)	NC score	0.714367 (rank : 3)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	99
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_HUMAN
θ value	1.52774e-15 (rank : 4)	NC score	0.706540 (rank : 4)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

ZN364_HUMAN
θ value	6.41864e-14 (rank : 5)	NC score	0.697526 (rank : 5)
Query Neighborhood Hits	159	Target Neighborhood Hits	140	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	8.38298e-14 (rank : 6)	NC score	0.695563 (rank : 6)
Query Neighborhood Hits	159	Target Neighborhood Hits	140	Shared Neighborhood Hits	93
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RNF6_HUMAN
θ value	1.80886e-08 (rank : 7)	NC score	0.596478 (rank : 12)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RNF12_MOUSE
θ value	2.36244e-08 (rank : 8)	NC score	0.604519 (rank : 9)
Query Neighborhood Hits	159	Target Neighborhood Hits	159	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF12_HUMAN
θ value	1.17247e-07 (rank : 9)	NC score	0.584995 (rank : 15)
Query Neighborhood Hits	159	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RN133_HUMAN
θ value	2.61198e-07 (rank : 10)	NC score	0.597471 (rank : 11)
Query Neighborhood Hits	159	Target Neighborhood Hits	108	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RNF38_HUMAN
θ value	4.45536e-07 (rank : 11)	NC score	0.585034 (rank : 14)
Query Neighborhood Hits	159	Target Neighborhood Hits	155	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

GOLI_MOUSE
θ value	5.81887e-07 (rank : 12)	NC score	0.586548 (rank : 13)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	90
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
θ value	7.59969e-07 (rank : 13)	NC score	0.583054 (rank : 16)
Query Neighborhood Hits	159	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RNF38_MOUSE
θ value	7.59969e-07 (rank : 14)	NC score	0.582062 (rank : 17)
Query Neighborhood Hits	159	Target Neighborhood Hits	153	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN167_HUMAN
θ value	1.69304e-06 (rank : 15)	NC score	0.556796 (rank : 18)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	3.77169e-06 (rank : 16)	NC score	0.553427 (rank : 19)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN165_HUMAN
θ value	4.92598e-06 (rank : 17)	NC score	0.612728 (rank : 7)
Query Neighborhood Hits	159	Target Neighborhood Hits	151	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

DZIP3_MOUSE
θ value	1.43324e-05 (rank : 18)	NC score	0.420162 (rank : 31)
Query Neighborhood Hits	159	Target Neighborhood Hits	414	Shared Neighborhood Hits	97
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

ZSWM2_MOUSE
θ value	1.43324e-05 (rank : 19)	NC score	0.437854 (rank : 30)
Query Neighborhood Hits	159	Target Neighborhood Hits	132	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

DZIP3_HUMAN
θ value	1.87187e-05 (rank : 20)	NC score	0.411903 (rank : 36)
Query Neighborhood Hits	159	Target Neighborhood Hits	399	Shared Neighborhood Hits	95
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RNF11_HUMAN
θ value	1.87187e-05 (rank : 21)	NC score	0.605602 (rank : 8)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	1.87187e-05 (rank : 22)	NC score	0.603866 (rank : 10)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RNF13_HUMAN
θ value	1.87187e-05 (rank : 23)	NC score	0.538247 (rank : 23)
Query Neighborhood Hits	159	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	1.87187e-05 (rank : 24)	NC score	0.544105 (rank : 21)
Query Neighborhood Hits	159	Target Neighborhood Hits	164	Shared Neighborhood Hits	91
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF8_HUMAN
θ value	1.87187e-05 (rank : 25)	NC score	0.324175 (rank : 46)
Query Neighborhood Hits	159	Target Neighborhood Hits	622	Shared Neighborhood Hits	110
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RN139_HUMAN
θ value	7.1131e-05 (rank : 26)	NC score	0.475813 (rank : 26)
Query Neighborhood Hits	159	Target Neighborhood Hits	130	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
θ value	7.1131e-05 (rank : 27)	NC score	0.469434 (rank : 27)
Query Neighborhood Hits	159	Target Neighborhood Hits	131	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

RNF8_MOUSE
θ value	9.29e-05 (rank : 28)	NC score	0.330844 (rank : 42)
Query Neighborhood Hits	159	Target Neighborhood Hits	618	Shared Neighborhood Hits	109
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

ZSWM2_HUMAN
θ value	0.00035302 (rank : 29)	NC score	0.406821 (rank : 37)
Query Neighborhood Hits	159	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

AMFR2_HUMAN
θ value	0.000461057 (rank : 30)	NC score	0.458932 (rank : 29)
Query Neighborhood Hits	159	Target Neighborhood Hits	219	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	0.000461057 (rank : 31)	NC score	0.464764 (rank : 28)
Query Neighborhood Hits	159	Target Neighborhood Hits	208	Shared Neighborhood Hits	107
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

PEX10_HUMAN
θ value	0.00102713 (rank : 32)	NC score	0.348793 (rank : 38)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	109
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RN103_HUMAN
θ value	0.00134147 (rank : 33)	NC score	0.415750 (rank : 34)
Query Neighborhood Hits	159	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	0.00134147 (rank : 34)	NC score	0.417670 (rank : 32)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN122_HUMAN
θ value	0.00228821 (rank : 35)	NC score	0.541627 (rank : 22)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	0.00228821 (rank : 36)	NC score	0.544173 (rank : 20)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF24_HUMAN
θ value	0.00390308 (rank : 37)	NC score	0.522367 (rank : 25)
Query Neighborhood Hits	159	Target Neighborhood Hits	122	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	0.00390308 (rank : 38)	NC score	0.524394 (rank : 24)
Query Neighborhood Hits	159	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF41_HUMAN
θ value	0.00509761 (rank : 39)	NC score	0.292155 (rank : 52)
Query Neighborhood Hits	159	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.00509761 (rank : 40)	NC score	0.292527 (rank : 51)
Query Neighborhood Hits	159	Target Neighborhood Hits	224	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_MOUSE
θ value	0.00665767 (rank : 41)	NC score	0.328951 (rank : 43)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI60_HUMAN
θ value	0.00665767 (rank : 42)	NC score	0.121643 (rank : 118)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

CHFR_HUMAN
θ value	0.00869519 (rank : 43)	NC score	0.328652 (rank : 44)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	95
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	0.00869519 (rank : 44)	NC score	0.332418 (rank : 41)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	94
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI13_MOUSE
θ value	0.00869519 (rank : 45)	NC score	0.203028 (rank : 64)
Query Neighborhood Hits	159	Target Neighborhood Hits	282	Shared Neighborhood Hits	90
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
θ value	0.0113563 (rank : 46)	NC score	0.200455 (rank : 69)
Query Neighborhood Hits	159	Target Neighborhood Hits	274	Shared Neighborhood Hits	90
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI30_MOUSE
θ value	0.0193708 (rank : 47)	NC score	0.124195 (rank : 114)
Query Neighborhood Hits	159	Target Neighborhood Hits	434	Shared Neighborhood Hits	64
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TTC3_HUMAN
θ value	0.0252991 (rank : 48)	NC score	0.241456 (rank : 54)
Query Neighborhood Hits	159	Target Neighborhood Hits	664	Shared Neighborhood Hits	82
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

PRP40_MOUSE
θ value	0.0330416 (rank : 49)	NC score	0.049793 (rank : 243)
Query Neighborhood Hits	159	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RN141_HUMAN
θ value	0.0330416 (rank : 50)	NC score	0.415590 (rank : 35)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.0330416 (rank : 51)	NC score	0.416529 (rank : 33)
Query Neighborhood Hits	159	Target Neighborhood Hits	200	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RNF4_HUMAN
θ value	0.0330416 (rank : 52)	NC score	0.321818 (rank : 47)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	93
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

ZN363_HUMAN
θ value	0.0330416 (rank : 53)	NC score	0.317847 (rank : 49)
Query Neighborhood Hits	159	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ZN363_MOUSE
θ value	0.0330416 (rank : 54)	NC score	0.327738 (rank : 45)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

BRAP_HUMAN
θ value	0.0563607 (rank : 55)	NC score	0.210226 (rank : 60)
Query Neighborhood Hits	159	Target Neighborhood Hits	560	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	0.0563607 (rank : 56)	NC score	0.233207 (rank : 55)
Query Neighborhood Hits	159	Target Neighborhood Hits	409	Shared Neighborhood Hits	76
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

RBX2_HUMAN
θ value	0.0563607 (rank : 57)	NC score	0.345013 (rank : 40)
Query Neighborhood Hits	159	Target Neighborhood Hits	83	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RBX2_MOUSE
θ value	0.0563607 (rank : 58)	NC score	0.345724 (rank : 39)
Query Neighborhood Hits	159	Target Neighborhood Hits	82	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RNF25_HUMAN
θ value	0.0563607 (rank : 59)	NC score	0.197466 (rank : 70)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	33
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RNF25_MOUSE
θ value	0.0563607 (rank : 60)	NC score	0.209013 (rank : 61)
Query Neighborhood Hits	159	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

TRI39_HUMAN
θ value	0.0563607 (rank : 61)	NC score	0.138239 (rank : 97)
Query Neighborhood Hits	159	Target Neighborhood Hits	693	Shared Neighborhood Hits	94
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.0563607 (rank : 62)	NC score	0.138117 (rank : 98)
Query Neighborhood Hits	159	Target Neighborhood Hits	691	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM8_HUMAN
θ value	0.0563607 (rank : 63)	NC score	0.137523 (rank : 100)
Query Neighborhood Hits	159	Target Neighborhood Hits	650	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	0.0563607 (rank : 64)	NC score	0.136388 (rank : 102)
Query Neighborhood Hits	159	Target Neighborhood Hits	674	Shared Neighborhood Hits	56
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

LEO1_MOUSE
θ value	0.0961366 (rank : 65)	NC score	0.034057 (rank : 246)
Query Neighborhood Hits	159	Target Neighborhood Hits	946	Shared Neighborhood Hits	20
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TRI65_HUMAN
θ value	0.0961366 (rank : 66)	NC score	0.202877 (rank : 65)
Query Neighborhood Hits	159	Target Neighborhood Hits	330	Shared Neighborhood Hits	94
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

DTX3_HUMAN
θ value	0.125558 (rank : 67)	NC score	0.203862 (rank : 63)
Query Neighborhood Hits	159	Target Neighborhood Hits	198	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RBBP6_MOUSE
θ value	0.125558 (rank : 68)	NC score	0.086432 (rank : 177)
Query Neighborhood Hits	159	Target Neighborhood Hits	1014	Shared Neighborhood Hits	72
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RNF32_HUMAN
θ value	0.125558 (rank : 69)	NC score	0.319156 (rank : 48)
Query Neighborhood Hits	159	Target Neighborhood Hits	133	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

DTX3_MOUSE
θ value	0.163984 (rank : 70)	NC score	0.201002 (rank : 68)
Query Neighborhood Hits	159	Target Neighborhood Hits	202	Shared Neighborhood Hits	76
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RO52_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.119061 (rank : 123)
Query Neighborhood Hits	159	Target Neighborhood Hits	419	Shared Neighborhood Hits	80
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

CM007_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.208490 (rank : 62)
Query Neighborhood Hits	159	Target Neighborhood Hits	416	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RN123_HUMAN
θ value	0.279714 (rank : 73)	NC score	0.108317 (rank : 138)
Query Neighborhood Hits	159	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRI22_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.115919 (rank : 129)
Query Neighborhood Hits	159	Target Neighborhood Hits	396	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI59_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.160025 (rank : 79)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	0.279714 (rank : 76)	NC score	0.163048 (rank : 75)
Query Neighborhood Hits	159	Target Neighborhood Hits	292	Shared Neighborhood Hits	81
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI62_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.114736 (rank : 130)
Query Neighborhood Hits	159	Target Neighborhood Hits	584	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.118370 (rank : 124)
Query Neighborhood Hits	159	Target Neighborhood Hits	478	Shared Neighborhood Hits	68
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI35_HUMAN
θ value	0.365318 (rank : 79)	NC score	0.149798 (rank : 93)
Query Neighborhood Hits	159	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI60_MOUSE
θ value	0.365318 (rank : 80)	NC score	0.107100 (rank : 140)
Query Neighborhood Hits	159	Target Neighborhood Hits	240	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

CM007_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.187162 (rank : 71)
Query Neighborhood Hits	159	Target Neighborhood Hits	422	Shared Neighborhood Hits	79
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

RNF32_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.302695 (rank : 50)
Query Neighborhood Hits	159	Target Neighborhood Hits	129	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

GPTC8_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.042081 (rank : 245)
Query Neighborhood Hits	159	Target Neighborhood Hits	366	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

MYPT1_MOUSE
θ value	0.62314 (rank : 84)	NC score	0.017585 (rank : 257)
Query Neighborhood Hits	159	Target Neighborhood Hits	539	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

RN123_MOUSE
θ value	0.62314 (rank : 85)	NC score	0.102550 (rank : 146)
Query Neighborhood Hits	159	Target Neighborhood Hits	174	Shared Neighborhood Hits	54
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRAIP_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.160873 (rank : 77)
Query Neighborhood Hits	159	Target Neighborhood Hits	780	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.160291 (rank : 78)
Query Neighborhood Hits	159	Target Neighborhood Hits	745	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRIM5_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.123898 (rank : 116)
Query Neighborhood Hits	159	Target Neighborhood Hits	424	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

CBLC_MOUSE
θ value	0.813845 (rank : 89)	NC score	0.184020 (rank : 72)
Query Neighborhood Hits	159	Target Neighborhood Hits	186	Shared Neighborhood Hits	77
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

M3K1_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.009271 (rank : 268)
Query Neighborhood Hits	159	Target Neighborhood Hits	952	Shared Neighborhood Hits	16
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MYPT1_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.016648 (rank : 258)
Query Neighborhood Hits	159	Target Neighborhood Hits	723	Shared Neighborhood Hits	14
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

RN166_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.138761 (rank : 96)
Query Neighborhood Hits	159	Target Neighborhood Hits	240	Shared Neighborhood Hits	70
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	0.813845 (rank : 93)	NC score	0.137869 (rank : 99)
Query Neighborhood Hits	159	Target Neighborhood Hits	248	Shared Neighborhood Hits	70
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

PCGF4_HUMAN
θ value	1.06291 (rank : 94)	NC score	0.159871 (rank : 80)
Query Neighborhood Hits	159	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.158579 (rank : 81)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	70
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

TRAF7_HUMAN
θ value	1.38821 (rank : 96)	NC score	0.053207 (rank : 229)
Query Neighborhood Hits	159	Target Neighborhood Hits	482	Shared Neighborhood Hits	53
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	1.38821 (rank : 97)	NC score	0.052197 (rank : 233)
Query Neighborhood Hits	159	Target Neighborhood Hits	470	Shared Neighborhood Hits	48
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

NFX1_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.043179 (rank : 244)
Query Neighborhood Hits	159	Target Neighborhood Hits	405	Shared Neighborhood Hits	20
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PZRN3_HUMAN
θ value	1.81305 (rank : 99)	NC score	0.127388 (rank : 111)
Query Neighborhood Hits	159	Target Neighborhood Hits	461	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	1.81305 (rank : 100)	NC score	0.127946 (rank : 109)
Query Neighborhood Hits	159	Target Neighborhood Hits	447	Shared Neighborhood Hits	83
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RN175_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.284486 (rank : 53)
Query Neighborhood Hits	159	Target Neighborhood Hits	68	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

CBLB_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.154195 (rank : 85)
Query Neighborhood Hits	159	Target Neighborhood Hits	261	Shared Neighborhood Hits	77
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	2.36792 (rank : 103)	NC score	0.153288 (rank : 89)
Query Neighborhood Hits	159	Target Neighborhood Hits	277	Shared Neighborhood Hits	75
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.155144 (rank : 84)
Query Neighborhood Hits	159	Target Neighborhood Hits	173	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

MAGL2_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.011011 (rank : 264)
Query Neighborhood Hits	159	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ04	Gene names	Magel2
Domain Architecture
Description	MAGE-like protein 2 (Protein nS7).

MYCB2_HUMAN
θ value	2.36792 (rank : 106)	NC score	0.085577 (rank : 180)
Query Neighborhood Hits	159	Target Neighborhood Hits	390	Shared Neighborhood Hits	43
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
θ value	2.36792 (rank : 107)	NC score	0.086406 (rank : 178)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RN168_HUMAN
θ value	2.36792 (rank : 108)	NC score	0.127770 (rank : 110)
Query Neighborhood Hits	159	Target Neighborhood Hits	370	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI65_MOUSE
θ value	2.36792 (rank : 109)	NC score	0.182150 (rank : 73)
Query Neighborhood Hits	159	Target Neighborhood Hits	340	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

AP3B2_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.015701 (rank : 259)
Query Neighborhood Hits	159	Target Neighborhood Hits	246	Shared Neighborhood Hits	11
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

APC11_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.211649 (rank : 59)
Query Neighborhood Hits	159	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

APC11_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.216589 (rank : 58)
Query Neighborhood Hits	159	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

CBL_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.157247 (rank : 83)
Query Neighborhood Hits	159	Target Neighborhood Hits	353	Shared Neighborhood Hits	79
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.153861 (rank : 86)
Query Neighborhood Hits	159	Target Neighborhood Hits	426	Shared Neighborhood Hits	81
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

DMP1_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.026609 (rank : 249)
Query Neighborhood Hits	159	Target Neighborhood Hits	498	Shared Neighborhood Hits	17
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

IPP2_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.028179 (rank : 248)
Query Neighborhood Hits	159	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

LNX2_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.090823 (rank : 165)
Query Neighborhood Hits	159	Target Neighborhood Hits	407	Shared Neighborhood Hits	83
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RAPSN_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.163166 (rank : 74)
Query Neighborhood Hits	159	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

TOPRS_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.224209 (rank : 57)
Query Neighborhood Hits	159	Target Neighborhood Hits	286	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.225514 (rank : 56)
Query Neighborhood Hits	159	Target Neighborhood Hits	263	Shared Neighborhood Hits	98
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI10_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.113848 (rank : 133)
Query Neighborhood Hits	159	Target Neighborhood Hits	315	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

WEE1B_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.002248 (rank : 278)
Query Neighborhood Hits	159	Target Neighborhood Hits	836	Shared Neighborhood Hits	8
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

CSKI2_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.005463 (rank : 275)
Query Neighborhood Hits	159	Target Neighborhood Hits	747	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PCGF2_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.152283 (rank : 91)
Query Neighborhood Hits	159	Target Neighborhood Hits	222	Shared Neighborhood Hits	73
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.152391 (rank : 90)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	72
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TACC2_MOUSE
θ value	4.03905 (rank : 126)	NC score	0.008510 (rank : 270)
Query Neighborhood Hits	159	Target Neighborhood Hits	774	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TGON2_HUMAN
θ value	4.03905 (rank : 127)	NC score	0.020542 (rank : 253)
Query Neighborhood Hits	159	Target Neighborhood Hits	1037	Shared Neighborhood Hits	29
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TRI68_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.100792 (rank : 150)
Query Neighborhood Hits	159	Target Neighborhood Hits	267	Shared Neighborhood Hits	62
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

ATS19_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.003287 (rank : 276)
Query Neighborhood Hits	159	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CACB2_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.009753 (rank : 267)
Query Neighborhood Hits	159	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

ETV6_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.008603 (rank : 269)
Query Neighborhood Hits	159	Target Neighborhood Hits	120	Shared Neighborhood Hits	2
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

FGD5_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.007681 (rank : 272)
Query Neighborhood Hits	159	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

NPBL_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.024826 (rank : 250)
Query Neighborhood Hits	159	Target Neighborhood Hits	1041	Shared Neighborhood Hits	24
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RBX1_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.202699 (rank : 66)
Query Neighborhood Hits	159	Target Neighborhood Hits	51	Shared Neighborhood Hits	45
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.202699 (rank : 67)
Query Neighborhood Hits	159	Target Neighborhood Hits	51	Shared Neighborhood Hits	45
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

UB7I1_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.013857 (rank : 261)
Query Neighborhood Hits	159	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

VPS11_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.092391 (rank : 162)
Query Neighborhood Hits	159	Target Neighborhood Hits	86	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

VPS11_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.093173 (rank : 161)
Query Neighborhood Hits	159	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

AKAP2_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.014050 (rank : 260)
Query Neighborhood Hits	159	Target Neighborhood Hits	507	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

CRNL1_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.012344 (rank : 263)
Query Neighborhood Hits	159	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

DLGP4_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.010327 (rank : 265)
Query Neighborhood Hits	159	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

ENL_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.021449 (rank : 251)
Query Neighborhood Hits	159	Target Neighborhood Hits	305	Shared Neighborhood Hits	11
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

HN1_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.019761 (rank : 254)
Query Neighborhood Hits	159	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK76, Q53FG7, Q7Z2D2, Q7Z2F0	Gene names	HN1, ARM2
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1 protein (Androgen-regulated protein 2).

HRX_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.009959 (rank : 266)
Query Neighborhood Hits	159	Target Neighborhood Hits	825	Shared Neighborhood Hits	20
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IRX6_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.006314 (rank : 273)
Query Neighborhood Hits	159	Target Neighborhood Hits	262	Shared Neighborhood Hits	3
SwissProt Accessions	P78412, Q7Z2K0	Gene names	IRX6, IRX7, IRXB3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3).

NFM_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.003112 (rank : 277)
Query Neighborhood Hits	159	Target Neighborhood Hits	1159	Shared Neighborhood Hits	19
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PKHA4_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.012682 (rank : 262)
Query Neighborhood Hits	159	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RAPSN_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.153573 (rank : 87)
Query Neighborhood Hits	159	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

SRRM2_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.018927 (rank : 256)
Query Neighborhood Hits	159	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRIM6_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.103021 (rank : 145)
Query Neighborhood Hits	159	Target Neighborhood Hits	451	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

BAT2_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.006225 (rank : 274)
Query Neighborhood Hits	159	Target Neighborhood Hits	947	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BFAR_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.134654 (rank : 103)
Query Neighborhood Hits	159	Target Neighborhood Hits	232	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

LRCH4_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.001224 (rank : 279)
Query Neighborhood Hits	159	Target Neighborhood Hits	305	Shared Neighborhood Hits	2
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

M4K1_HUMAN
θ value	8.99809 (rank : 154)	NC score	-0.004247 (rank : 281)
Query Neighborhood Hits	159	Target Neighborhood Hits	884	Shared Neighborhood Hits	5
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

MARH2_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.020621 (rank : 252)
Query Neighborhood Hits	159	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M02, Q8C4Q5	Gene names	March2
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 2 (Membrane-associated RING-CH protein II) (MARCH-II).

NUCKS_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.028402 (rank : 247)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PHF7_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.019429 (rank : 255)
Query Neighborhood Hits	159	Target Neighborhood Hits	71	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

SLY_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.007983 (rank : 271)
Query Neighborhood Hits	159	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

ZN592_HUMAN
θ value	8.99809 (rank : 159)	NC score	-0.002971 (rank : 280)
Query Neighborhood Hits	159	Target Neighborhood Hits	762	Shared Neighborhood Hits	5
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

BFAR_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.124086 (rank : 115)
Query Neighborhood Hits	159	Target Neighborhood Hits	222	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BRCA1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.089726 (rank : 172)
Query Neighborhood Hits	159	Target Neighborhood Hits	381	Shared Neighborhood Hits	67
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.082421 (rank : 190)
Query Neighborhood Hits	159	Target Neighborhood Hits	436	Shared Neighborhood Hits	66
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BSPRY_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.053234 (rank : 228)
Query Neighborhood Hits	159	Target Neighborhood Hits	115	Shared Neighborhood Hits	18
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.055539 (rank : 220)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

DTX3L_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.125411 (rank : 112)
Query Neighborhood Hits	159	Target Neighborhood Hits	187	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

ERMAP_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.050019 (rank : 241)
Query Neighborhood Hits	159	Target Neighborhood Hits	155	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

LNX1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.075002 (rank : 201)
Query Neighborhood Hits	159	Target Neighborhood Hits	379	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.073883 (rank : 202)
Query Neighborhood Hits	159	Target Neighborhood Hits	377	Shared Neighborhood Hits	72
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.082737 (rank : 189)
Query Neighborhood Hits	159	Target Neighborhood Hits	389	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

MEFV_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.060940 (rank : 214)
Query Neighborhood Hits	159	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.052217 (rank : 232)
Query Neighborhood Hits	159	Target Neighborhood Hits	236	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MGRN1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.085086 (rank : 181)
Query Neighborhood Hits	159	Target Neighborhood Hits	192	Shared Neighborhood Hits	47
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.078114 (rank : 196)
Query Neighborhood Hits	159	Target Neighborhood Hits	149	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

PCGF6_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.098457 (rank : 152)
Query Neighborhood Hits	159	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.098280 (rank : 153)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PZRN4_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.094322 (rank : 159)
Query Neighborhood Hits	159	Target Neighborhood Hits	438	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

R113A_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.055497 (rank : 221)
Query Neighborhood Hits	159	Target Neighborhood Hits	177	Shared Neighborhood Hits	44
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.055234 (rank : 223)
Query Neighborhood Hits	159	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAD18_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.131633 (rank : 106)
Query Neighborhood Hits	159	Target Neighborhood Hits	284	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.136957 (rank : 101)
Query Neighborhood Hits	159	Target Neighborhood Hits	230	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAG1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.072583 (rank : 204)
Query Neighborhood Hits	159	Target Neighborhood Hits	203	Shared Neighborhood Hits	52
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.068941 (rank : 205)
Query Neighborhood Hits	159	Target Neighborhood Hits	189	Shared Neighborhood Hits	52
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RBBP6_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.064069 (rank : 211)
Query Neighborhood Hits	159	Target Neighborhood Hits	1135	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RFPL1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.051105 (rank : 236)
Query Neighborhood Hits	159	Target Neighborhood Hits	119	Shared Neighborhood Hits	24
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.052431 (rank : 231)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	26
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.053325 (rank : 227)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFWD2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.090579 (rank : 169)
Query Neighborhood Hits	159	Target Neighborhood Hits	518	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.090856 (rank : 164)
Query Neighborhood Hits	159	Target Neighborhood Hits	535	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.132270 (rank : 104)
Query Neighborhood Hits	159	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.129621 (rank : 108)
Query Neighborhood Hits	159	Target Neighborhood Hits	220	Shared Neighborhood Hits	65
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.119508 (rank : 120)
Query Neighborhood Hits	159	Target Neighborhood Hits	201	Shared Neighborhood Hits	65
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.119497 (rank : 121)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN125_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.131672 (rank : 105)
Query Neighborhood Hits	159	Target Neighborhood Hits	230	Shared Neighborhood Hits	70
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.113779 (rank : 134)
Query Neighborhood Hits	159	Target Neighborhood Hits	220	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN146_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.081985 (rank : 191)
Query Neighborhood Hits	159	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.080286 (rank : 192)
Query Neighborhood Hits	159	Target Neighborhood Hits	161	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN168_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.112505 (rank : 135)
Query Neighborhood Hits	159	Target Neighborhood Hits	440	Shared Neighborhood Hits	65
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN169_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.060810 (rank : 215)
Query Neighborhood Hits	159	Target Neighborhood Hits	203	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.056258 (rank : 219)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.153498 (rank : 88)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	84
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.150412 (rank : 92)
Query Neighborhood Hits	159	Target Neighborhood Hits	211	Shared Neighborhood Hits	82
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF37_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.054283 (rank : 224)
Query Neighborhood Hits	159	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

RNF39_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.083241 (rank : 188)
Query Neighborhood Hits	159	Target Neighborhood Hits	200	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF5_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.120937 (rank : 119)
Query Neighborhood Hits	159	Target Neighborhood Hits	206	Shared Neighborhood Hits	73
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.117869 (rank : 125)
Query Neighborhood Hits	159	Target Neighborhood Hits	206	Shared Neighborhood Hits	72
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RO52_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.098904 (rank : 151)
Query Neighborhood Hits	159	Target Neighborhood Hits	360	Shared Neighborhood Hits	69
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

SMRA3_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.066973 (rank : 207)
Query Neighborhood Hits	159	Target Neighborhood Hits	265	Shared Neighborhood Hits	70
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.065422 (rank : 210)
Query Neighborhood Hits	159	Target Neighborhood Hits	267	Shared Neighborhood Hits	72
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRAF4_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.052466 (rank : 230)
Query Neighborhood Hits	159	Target Neighborhood Hits	373	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF5_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.051208 (rank : 235)
Query Neighborhood Hits	159	Target Neighborhood Hits	355	Shared Neighborhood Hits	46
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF6_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.075560 (rank : 200)
Query Neighborhood Hits	159	Target Neighborhood Hits	267	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.077594 (rank : 198)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	61
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI10_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.101198 (rank : 149)
Query Neighborhood Hits	159	Target Neighborhood Hits	285	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI11_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.095898 (rank : 156)
Query Neighborhood Hits	159	Target Neighborhood Hits	316	Shared Neighborhood Hits	63
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.095220 (rank : 157)
Query Neighborhood Hits	159	Target Neighborhood Hits	329	Shared Neighborhood Hits	63
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI12_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.116400 (rank : 127)
Query Neighborhood Hits	159	Target Neighborhood Hits	387	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI14_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.055445 (rank : 222)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	21
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.058603 (rank : 217)
Query Neighborhood Hits	159	Target Neighborhood Hits	137	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI15_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.089029 (rank : 174)
Query Neighborhood Hits	159	Target Neighborhood Hits	395	Shared Neighborhood Hits	61
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI16_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.053957 (rank : 225)
Query Neighborhood Hits	159	Target Neighborhood Hits	231	Shared Neighborhood Hits	22
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.050885 (rank : 238)
Query Neighborhood Hits	159	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI17_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.094533 (rank : 158)
Query Neighborhood Hits	159	Target Neighborhood Hits	318	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI17_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.087900 (rank : 175)
Query Neighborhood Hits	159	Target Neighborhood Hits	620	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI18_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.066286 (rank : 208)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	53
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.066026 (rank : 209)
Query Neighborhood Hits	159	Target Neighborhood Hits	292	Shared Neighborhood Hits	54
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI25_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.102540 (rank : 147)
Query Neighborhood Hits	159	Target Neighborhood Hits	472	Shared Neighborhood Hits	70
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.108288 (rank : 139)
Query Neighborhood Hits	159	Target Neighborhood Hits	446	Shared Neighborhood Hits	73
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI26_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.113864 (rank : 132)
Query Neighborhood Hits	159	Target Neighborhood Hits	335	Shared Neighborhood Hits	75
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.117391 (rank : 126)
Query Neighborhood Hits	159	Target Neighborhood Hits	339	Shared Neighborhood Hits	79
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI27_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.084209 (rank : 186)
Query Neighborhood Hits	159	Target Neighborhood Hits	273	Shared Neighborhood Hits	54
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.083807 (rank : 187)
Query Neighborhood Hits	159	Target Neighborhood Hits	261	Shared Neighborhood Hits	52
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI29_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.051522 (rank : 234)
Query Neighborhood Hits	159	Target Neighborhood Hits	273	Shared Neighborhood Hits	21
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.053497 (rank : 226)
Query Neighborhood Hits	159	Target Neighborhood Hits	306	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI31_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.116325 (rank : 128)
Query Neighborhood Hits	159	Target Neighborhood Hits	299	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI32_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.084538 (rank : 183)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	52
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.084305 (rank : 184)
Query Neighborhood Hits	159	Target Neighborhood Hits	271	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI34_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.093328 (rank : 160)
Query Neighborhood Hits	159	Target Neighborhood Hits	416	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.084872 (rank : 182)
Query Neighborhood Hits	159	Target Neighborhood Hits	332	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI35_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.130101 (rank : 107)
Query Neighborhood Hits	159	Target Neighborhood Hits	465	Shared Neighborhood Hits	75
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI37_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.090959 (rank : 163)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.090669 (rank : 166)
Query Neighborhood Hits	159	Target Neighborhood Hits	316	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI38_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.089736 (rank : 171)
Query Neighborhood Hits	159	Target Neighborhood Hits	373	Shared Neighborhood Hits	51
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI40_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.125364 (rank : 113)
Query Neighborhood Hits	159	Target Neighborhood Hits	279	Shared Neighborhood Hits	67
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI41_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.079327 (rank : 194)
Query Neighborhood Hits	159	Target Neighborhood Hits	349	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI43_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.103266 (rank : 143)
Query Neighborhood Hits	159	Target Neighborhood Hits	341	Shared Neighborhood Hits	65
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI44_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.057962 (rank : 218)
Query Neighborhood Hits	159	Target Neighborhood Hits	393	Shared Neighborhood Hits	24
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.058910 (rank : 216)
Query Neighborhood Hits	159	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI46_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.050018 (rank : 242)
Query Neighborhood Hits	159	Target Neighborhood Hits	287	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI47_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.095993 (rank : 155)
Query Neighborhood Hits	159	Target Neighborhood Hits	286	Shared Neighborhood Hits	60
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.087059 (rank : 176)
Query Neighborhood Hits	159	Target Neighborhood Hits	295	Shared Neighborhood Hits	59
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI48_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.090623 (rank : 167)
Query Neighborhood Hits	159	Target Neighborhood Hits	192	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI49_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.090234 (rank : 170)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI50_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.111021 (rank : 136)
Query Neighborhood Hits	159	Target Neighborhood Hits	294	Shared Neighborhood Hits	65
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.114670 (rank : 131)
Query Neighborhood Hits	159	Target Neighborhood Hits	326	Shared Neighborhood Hits	78
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI52_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.103083 (rank : 144)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	56
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI54_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.079957 (rank : 193)
Query Neighborhood Hits	159	Target Neighborhood Hits	209	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.078132 (rank : 195)
Query Neighborhood Hits	159	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.072802 (rank : 203)
Query Neighborhood Hits	159	Target Neighborhood Hits	292	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI56_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.084277 (rank : 185)
Query Neighborhood Hits	159	Target Neighborhood Hits	339	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.068892 (rank : 206)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	57
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI63_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.077642 (rank : 197)
Query Neighborhood Hits	159	Target Neighborhood Hits	298	Shared Neighborhood Hits	38
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.077164 (rank : 199)
Query Neighborhood Hits	159	Target Neighborhood Hits	240	Shared Neighborhood Hits	38
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI68_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.098170 (rank : 154)
Query Neighborhood Hits	159	Target Neighborhood Hits	356	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI73_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.109318 (rank : 137)
Query Neighborhood Hits	159	Target Neighborhood Hits	258	Shared Neighborhood Hits	64
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.104722 (rank : 141)
Query Neighborhood Hits	159	Target Neighborhood Hits	249	Shared Neighborhood Hits	58
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM1_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.061519 (rank : 213)
Query Neighborhood Hits	159	Target Neighborhood Hits	345	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.062024 (rank : 212)
Query Neighborhood Hits	159	Target Neighborhood Hits	361	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM2_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.140096 (rank : 94)
Query Neighborhood Hits	159	Target Neighborhood Hits	330	Shared Neighborhood Hits	90
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.138867 (rank : 95)
Query Neighborhood Hits	159	Target Neighborhood Hits	331	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.122961 (rank : 117)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	89
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.119358 (rank : 122)
Query Neighborhood Hits	159	Target Neighborhood Hits	351	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM4_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.104290 (rank : 142)
Query Neighborhood Hits	159	Target Neighborhood Hits	321	Shared Neighborhood Hits	67
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM6_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.101270 (rank : 148)
Query Neighborhood Hits	159	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRIM7_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.089336 (rank : 173)
Query Neighborhood Hits	159	Target Neighborhood Hits	336	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM7_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.090593 (rank : 168)
Query Neighborhood Hits	159	Target Neighborhood Hits	358	Shared Neighborhood Hits	58
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

UHRF2_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.050190 (rank : 240)
Query Neighborhood Hits	159	Target Neighborhood Hits	269	Shared Neighborhood Hits	49
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

ZN179_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.085908 (rank : 179)
Query Neighborhood Hits	159	Target Neighborhood Hits	178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN294_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.050593 (rank : 239)
Query Neighborhood Hits	159	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

ZN294_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.051015 (rank : 237)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

ZN313_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.162874 (rank : 76)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.157288 (rank : 82)
Query Neighborhood Hits	159	Target Neighborhood Hits	273	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

PJA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	159	Target Neighborhood Hits	159	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
NC score	0.981463 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	159	Target Neighborhood Hits	145	Shared Neighborhood Hits	115
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RN126_MOUSE
NC score	0.714367 (rank : 3)	θ value	8.95645e-16 (rank : 3)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	99
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_HUMAN
NC score	0.706540 (rank : 4)	θ value	1.52774e-15 (rank : 4)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

ZN364_HUMAN
NC score	0.697526 (rank : 5)	θ value	6.41864e-14 (rank : 5)
Query Neighborhood Hits	159	Target Neighborhood Hits	140	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
NC score	0.695563 (rank : 6)	θ value	8.38298e-14 (rank : 6)
Query Neighborhood Hits	159	Target Neighborhood Hits	140	Shared Neighborhood Hits	93
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RN165_HUMAN
NC score	0.612728 (rank : 7)	θ value	4.92598e-06 (rank : 17)
Query Neighborhood Hits	159	Target Neighborhood Hits	151	Shared Neighborhood Hits	95
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RNF11_HUMAN
NC score	0.605602 (rank : 8)	θ value	1.87187e-05 (rank : 21)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF12_MOUSE
NC score	0.604519 (rank : 9)	θ value	2.36244e-08 (rank : 8)
Query Neighborhood Hits	159	Target Neighborhood Hits	159	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF11_MOUSE
NC score	0.603866 (rank : 10)	θ value	1.87187e-05 (rank : 22)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RN133_HUMAN
NC score	0.597471 (rank : 11)	θ value	2.61198e-07 (rank : 10)
Query Neighborhood Hits	159	Target Neighborhood Hits	108	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RNF6_HUMAN
NC score	0.596478 (rank : 12)	θ value	1.80886e-08 (rank : 7)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

GOLI_MOUSE
NC score	0.586548 (rank : 13)	θ value	5.81887e-07 (rank : 12)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	90
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

RNF38_HUMAN
NC score	0.585034 (rank : 14)	θ value	4.45536e-07 (rank : 11)
Query Neighborhood Hits	159	Target Neighborhood Hits	155	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF12_HUMAN
NC score	0.584995 (rank : 15)	θ value	1.17247e-07 (rank : 9)
Query Neighborhood Hits	159	Target Neighborhood Hits	173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

GOLI_HUMAN
NC score	0.583054 (rank : 16)	θ value	7.59969e-07 (rank : 13)
Query Neighborhood Hits	159	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RNF38_MOUSE
NC score	0.582062 (rank : 17)	θ value	7.59969e-07 (rank : 14)
Query Neighborhood Hits	159	Target Neighborhood Hits	153	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RN167_HUMAN
NC score	0.556796 (rank : 18)	θ value	1.69304e-06 (rank : 15)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
NC score	0.553427 (rank : 19)	θ value	3.77169e-06 (rank : 16)
Query Neighborhood Hits	159	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN122_MOUSE
NC score	0.544173 (rank : 20)	θ value	0.00228821 (rank : 36)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF13_MOUSE
NC score	0.544105 (rank : 21)	θ value	1.87187e-05 (rank : 24)
Query Neighborhood Hits	159	Target Neighborhood Hits	164	Shared Neighborhood Hits	91
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RN122_HUMAN
NC score	0.541627 (rank : 22)	θ value	0.00228821 (rank : 35)
Query Neighborhood Hits	159	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RNF13_HUMAN
NC score	0.538247 (rank : 23)	θ value	1.87187e-05 (rank : 23)
Query Neighborhood Hits	159	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF24_MOUSE
NC score	0.524394 (rank : 24)	θ value	0.00390308 (rank : 38)
Query Neighborhood Hits	159	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.522367 (rank : 25)	θ value	0.00390308 (rank : 37)
Query Neighborhood Hits	159	Target Neighborhood Hits	122	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RN139_HUMAN
NC score	0.475813 (rank : 26)	θ value	7.1131e-05 (rank : 26)
Query Neighborhood Hits	159	Target Neighborhood Hits	130	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

RN139_MOUSE
NC score	0.469434 (rank : 27)	θ value	7.1131e-05 (rank : 27)
Query Neighborhood Hits	159	Target Neighborhood Hits	131	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

AMFR_MOUSE
NC score	0.464764 (rank : 28)	θ value	0.000461057 (rank : 31)
Query Neighborhood Hits	159	Target Neighborhood Hits	208	Shared Neighborhood Hits	107
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.458932 (rank : 29)	θ value	0.000461057 (rank : 30)
Query Neighborhood Hits	159	Target Neighborhood Hits	219	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

ZSWM2_MOUSE
NC score	0.437854 (rank : 30)	θ value	1.43324e-05 (rank : 19)
Query Neighborhood Hits	159	Target Neighborhood Hits	132	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

DZIP3_MOUSE
NC score	0.420162 (rank : 31)	θ value	1.43324e-05 (rank : 18)
Query Neighborhood Hits	159	Target Neighborhood Hits	414	Shared Neighborhood Hits	97
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

RN103_MOUSE
NC score	0.417670 (rank : 32)	θ value	0.00134147 (rank : 34)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN141_MOUSE
NC score	0.416529 (rank : 33)	θ value	0.0330416 (rank : 51)
Query Neighborhood Hits	159	Target Neighborhood Hits	200	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN103_HUMAN
NC score	0.415750 (rank : 34)	θ value	0.00134147 (rank : 33)
Query Neighborhood Hits	159	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN141_HUMAN
NC score	0.415590 (rank : 35)	θ value	0.0330416 (rank : 50)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

DZIP3_HUMAN
NC score	0.411903 (rank : 36)	θ value	1.87187e-05 (rank : 20)
Query Neighborhood Hits	159	Target Neighborhood Hits	399	Shared Neighborhood Hits	95
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

ZSWM2_HUMAN
NC score	0.406821 (rank : 37)	θ value	0.00035302 (rank : 29)
Query Neighborhood Hits	159	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

PEX10_HUMAN
NC score	0.348793 (rank : 38)	θ value	0.00102713 (rank : 32)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	109
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RBX2_MOUSE
NC score	0.345724 (rank : 39)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	159	Target Neighborhood Hits	82	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTZ1, Q3UKF8	Gene names	Rnf7, Rbx2, Sag
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Sensitive to apoptosis gene protein).

RBX2_HUMAN
NC score	0.345013 (rank : 40)	θ value	0.0563607 (rank : 57)
Query Neighborhood Hits	159	Target Neighborhood Hits	83	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

CHFR_MOUSE
NC score	0.332418 (rank : 41)	θ value	0.00869519 (rank : 44)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	94
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RNF8_MOUSE
NC score	0.330844 (rank : 42)	θ value	9.29e-05 (rank : 28)
Query Neighborhood Hits	159	Target Neighborhood Hits	618	Shared Neighborhood Hits	109
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF4_MOUSE
NC score	0.328951 (rank : 43)	θ value	0.00665767 (rank : 41)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

CHFR_HUMAN
NC score	0.328652 (rank : 44)	θ value	0.00869519 (rank : 43)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	95
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

ZN363_MOUSE
NC score	0.327738 (rank : 45)	θ value	0.0330416 (rank : 54)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

RNF8_HUMAN
NC score	0.324175 (rank : 46)	θ value	1.87187e-05 (rank : 25)
Query Neighborhood Hits	159	Target Neighborhood Hits	622	Shared Neighborhood Hits	110
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF4_HUMAN
NC score	0.321818 (rank : 47)	θ value	0.0330416 (rank : 52)
Query Neighborhood Hits	159	Target Neighborhood Hits	212	Shared Neighborhood Hits	93
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF32_HUMAN
NC score	0.319156 (rank : 48)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	159	Target Neighborhood Hits	133	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

ZN363_HUMAN
NC score	0.317847 (rank : 49)	θ value	0.0330416 (rank : 53)
Query Neighborhood Hits	159	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

RNF32_MOUSE
NC score	0.302695 (rank : 50)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	159	Target Neighborhood Hits	129	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF41_MOUSE
NC score	0.292527 (rank : 51)	θ value	0.00509761 (rank : 40)
Query Neighborhood Hits	159	Target Neighborhood Hits	224	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.292155 (rank : 52)	θ value	0.00509761 (rank : 39)
Query Neighborhood Hits	159	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RN175_HUMAN
NC score	0.284486 (rank : 53)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	159	Target Neighborhood Hits	68	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

TTC3_HUMAN
NC score	0.241456 (rank : 54)	θ value	0.0252991 (rank : 48)
Query Neighborhood Hits	159	Target Neighborhood Hits	664	Shared Neighborhood Hits	82
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

BRAP_MOUSE
NC score	0.233207 (rank : 55)	θ value	0.0563607 (rank : 56)
Query Neighborhood Hits	159	Target Neighborhood Hits	409	Shared Neighborhood Hits	76
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

TOPRS_MOUSE
NC score	0.225514 (rank : 56)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	159	Target Neighborhood Hits	263	Shared Neighborhood Hits	98
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_HUMAN
NC score	0.224209 (rank : 57)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	159	Target Neighborhood Hits	286	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

APC11_MOUSE
NC score	0.216589 (rank : 58)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	159	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

APC11_HUMAN
NC score	0.211649 (rank : 59)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	159	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

BRAP_HUMAN
NC score	0.210226 (rank : 60)	θ value	0.0563607 (rank : 55)
Query Neighborhood Hits	159	Target Neighborhood Hits	560	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RNF25_MOUSE
NC score	0.209013 (rank : 61)	θ value	0.0563607 (rank : 60)
Query Neighborhood Hits	159	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

CM007_MOUSE
NC score	0.208490 (rank : 62)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	159	Target Neighborhood Hits	416	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DTX3_HUMAN
NC score	0.203862 (rank : 63)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	159	Target Neighborhood Hits	198	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

TRI13_MOUSE
NC score	0.203028 (rank : 64)	θ value	0.00869519 (rank : 45)
Query Neighborhood Hits	159	Target Neighborhood Hits	282	Shared Neighborhood Hits	90
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI65_HUMAN
NC score	0.202877 (rank : 65)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	159	Target Neighborhood Hits	330	Shared Neighborhood Hits	94
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RBX1_HUMAN
NC score	0.202699 (rank : 66)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	159	Target Neighborhood Hits	51	Shared Neighborhood Hits	45
SwissProt Accessions	P62877, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	RBX1, RNF75, ROC1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1) (Regulator of cullins 1) (RING finger protein 75) (Protein ZYP).

RBX1_MOUSE
NC score	0.202699 (rank : 67)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	159	Target Neighborhood Hits	51	Shared Neighborhood Hits	45
SwissProt Accessions	P62878, Q8N6Z8, Q9D1S2, Q9WUK9, Q9Y254	Gene names	Rbx1
Domain Architecture	No domain graphic available
Description	RING-box protein 1 (Rbx1).

DTX3_MOUSE
NC score	0.201002 (rank : 68)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	159	Target Neighborhood Hits	202	Shared Neighborhood Hits	76
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TRI13_HUMAN
NC score	0.200455 (rank : 69)	θ value	0.0113563 (rank : 46)
Query Neighborhood Hits	159	Target Neighborhood Hits	274	Shared Neighborhood Hits	90
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

RNF25_HUMAN
NC score	0.197466 (rank : 70)	θ value	0.0563607 (rank : 59)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	33
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

CM007_HUMAN
NC score	0.187162 (rank : 71)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	159	Target Neighborhood Hits	422	Shared Neighborhood Hits	79
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CBLC_MOUSE
NC score	0.184020 (rank : 72)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	159	Target Neighborhood Hits	186	Shared Neighborhood Hits	77
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

TRI65_MOUSE
NC score	0.182150 (rank : 73)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	159	Target Neighborhood Hits	340	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RAPSN_HUMAN
NC score	0.163166 (rank : 74)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	159	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

TRI59_MOUSE
NC score	0.163048 (rank : 75)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	159	Target Neighborhood Hits	292	Shared Neighborhood Hits	81
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

ZN313_HUMAN
NC score	0.162874 (rank : 76)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRAIP_HUMAN
NC score	0.160873 (rank : 77)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	159	Target Neighborhood Hits	780	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
NC score	0.160291 (rank : 78)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	159	Target Neighborhood Hits	745	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI59_HUMAN
NC score	0.160025 (rank : 79)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

PCGF4_HUMAN
NC score	0.159871 (rank : 80)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	159	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.158579 (rank : 81)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	70
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

ZN313_MOUSE
NC score	0.157288 (rank : 82)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	159	Target Neighborhood Hits	273	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

CBL_HUMAN
NC score	0.157247 (rank : 83)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	159	Target Neighborhood Hits	353	Shared Neighborhood Hits	79
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBLC_HUMAN
NC score	0.155144 (rank : 84)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	159	Target Neighborhood Hits	173	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLB_HUMAN
NC score	0.154195 (rank : 85)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	159	Target Neighborhood Hits	261	Shared Neighborhood Hits	77
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBL_MOUSE
NC score	0.153861 (rank : 86)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	159	Target Neighborhood Hits	426	Shared Neighborhood Hits	81
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

RAPSN_MOUSE
NC score	0.153573 (rank : 87)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	159	Target Neighborhood Hits	92	Shared Neighborhood Hits	47
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RN185_HUMAN
NC score	0.153498 (rank : 88)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	84
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

CBLB_MOUSE
NC score	0.153288 (rank : 89)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	159	Target Neighborhood Hits	277	Shared Neighborhood Hits	75
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

PCGF2_MOUSE
NC score	0.152391 (rank : 90)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	72
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.152283 (rank : 91)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	159	Target Neighborhood Hits	222	Shared Neighborhood Hits	73
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

RN185_MOUSE
NC score	0.150412 (rank : 92)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	159	Target Neighborhood Hits	211	Shared Neighborhood Hits	82
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI35_HUMAN
NC score	0.149798 (rank : 93)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	159	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRIM2_HUMAN
NC score	0.140096 (rank : 94)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	159	Target Neighborhood Hits	330	Shared Neighborhood Hits	90
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.138867 (rank : 95)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	159	Target Neighborhood Hits	331	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RN166_HUMAN
NC score	0.138761 (rank : 96)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	159	Target Neighborhood Hits	240	Shared Neighborhood Hits	70
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI39_HUMAN
NC score	0.138239 (rank : 97)	θ value	0.0563607 (rank : 61)
Query Neighborhood Hits	159	Target Neighborhood Hits	693	Shared Neighborhood Hits	94
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
NC score	0.138117 (rank : 98)	θ value	0.0563607 (rank : 62)
Query Neighborhood Hits	159	Target Neighborhood Hits	691	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RN166_MOUSE
NC score	0.137869 (rank : 99)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	159	Target Neighborhood Hits	248	Shared Neighborhood Hits	70
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRIM8_HUMAN
NC score	0.137523 (rank : 100)	θ value	0.0563607 (rank : 63)
Query Neighborhood Hits	159	Target Neighborhood Hits	650	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RAD18_MOUSE
NC score	0.136957 (rank : 101)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	159	Target Neighborhood Hits	230	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

TRIM8_MOUSE
NC score	0.136388 (rank : 102)	θ value	0.0563607 (rank : 64)
Query Neighborhood Hits	159	Target Neighborhood Hits	674	Shared Neighborhood Hits	56
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BFAR_MOUSE
NC score	0.134654 (rank : 103)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	159	Target Neighborhood Hits	232	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RING1_HUMAN
NC score	0.132270 (rank : 104)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	159	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RN125_HUMAN
NC score	0.131672 (rank : 105)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	159	Target Neighborhood Hits	230	Shared Neighborhood Hits	70
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RAD18_HUMAN
NC score	0.131633 (rank : 106)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	159	Target Neighborhood Hits	284	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

TRI35_MOUSE
NC score	0.130101 (rank : 107)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	159	Target Neighborhood Hits	465	Shared Neighborhood Hits	75
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

RING1_MOUSE
NC score	0.129621 (rank : 108)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	159	Target Neighborhood Hits	220	Shared Neighborhood Hits	65
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

PZRN3_MOUSE
NC score	0.127946 (rank : 109)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	159	Target Neighborhood Hits	447	Shared Neighborhood Hits	83
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RN168_HUMAN
NC score	0.127770 (rank : 110)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	159	Target Neighborhood Hits	370	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

PZRN3_HUMAN
NC score	0.127388 (rank : 111)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	159	Target Neighborhood Hits	461	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

DTX3L_HUMAN
NC score	0.125411 (rank : 112)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	159	Target Neighborhood Hits	187	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

TRI40_HUMAN
NC score	0.125364 (rank : 113)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	159	Target Neighborhood Hits	279	Shared Neighborhood Hits	67
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI30_MOUSE
NC score	0.124195 (rank : 114)	θ value	0.0193708 (rank : 47)
Query Neighborhood Hits	159	Target Neighborhood Hits	434	Shared Neighborhood Hits	64
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

BFAR_HUMAN
NC score	0.124086 (rank : 115)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	159	Target Neighborhood Hits	222	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRIM5_HUMAN
NC score	0.123898 (rank : 116)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	159	Target Neighborhood Hits	424	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM3_HUMAN
NC score	0.122961 (rank : 117)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	89
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI60_HUMAN
NC score	0.121643 (rank : 118)	θ value	0.00665767 (rank : 42)
Query Neighborhood Hits	159	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

RNF5_HUMAN
NC score	0.120937 (rank : 119)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	159	Target Neighborhood Hits	206	Shared Neighborhood Hits	73
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RING2_HUMAN
NC score	0.119508 (rank : 120)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	159	Target Neighborhood Hits	201	Shared Neighborhood Hits	65
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.119497 (rank : 121)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

TRIM3_MOUSE
NC score	0.119358 (rank : 122)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	159	Target Neighborhood Hits	351	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

RO52_HUMAN
NC score	0.119061 (rank : 123)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	159	Target Neighborhood Hits	419	Shared Neighborhood Hits	80
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI62_MOUSE
NC score	0.118370 (rank : 124)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	159	Target Neighborhood Hits	478	Shared Neighborhood Hits	68
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RNF5_MOUSE
NC score	0.117869 (rank : 125)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	159	Target Neighborhood Hits	206	Shared Neighborhood Hits	72
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI26_MOUSE
NC score	0.117391 (rank : 126)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	159	Target Neighborhood Hits	339	Shared Neighborhood Hits	79
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI12_MOUSE
NC score	0.116400 (rank : 127)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	159	Target Neighborhood Hits	387	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI31_HUMAN
NC score	0.116325 (rank : 128)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	159	Target Neighborhood Hits	299	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI22_HUMAN
NC score	0.115919 (rank : 129)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	159	Target Neighborhood Hits	396	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI62_HUMAN
NC score	0.114736 (rank : 130)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	159	Target Neighborhood Hits	584	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI50_MOUSE
NC score	0.114670 (rank : 131)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	159	Target Neighborhood Hits	326	Shared Neighborhood Hits	78
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI26_HUMAN
NC score	0.113864 (rank : 132)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	159	Target Neighborhood Hits	335	Shared Neighborhood Hits	75
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI10_HUMAN
NC score	0.113848 (rank : 133)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	159	Target Neighborhood Hits	315	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

RN125_MOUSE
NC score	0.113779 (rank : 134)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	159	Target Neighborhood Hits	220	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN168_MOUSE
NC score	0.112505 (rank : 135)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	159	Target Neighborhood Hits	440	Shared Neighborhood Hits	65
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI50_HUMAN
NC score	0.111021 (rank : 136)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	159	Target Neighborhood Hits	294	Shared Neighborhood Hits	65
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI73_HUMAN
NC score	0.109318 (rank : 137)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	159	Target Neighborhood Hits	258	Shared Neighborhood Hits	64
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

RN123_HUMAN
NC score	0.108317 (rank : 138)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	159	Target Neighborhood Hits	175	Shared Neighborhood Hits	56
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRI25_MOUSE
NC score	0.108288 (rank : 139)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	159	Target Neighborhood Hits	446	Shared Neighborhood Hits	73
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI60_MOUSE
NC score	0.107100 (rank : 140)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	159	Target Neighborhood Hits	240	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI74_HUMAN
NC score	0.104722 (rank : 141)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	159	Target Neighborhood Hits	249	Shared Neighborhood Hits	58
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM4_HUMAN
NC score	0.104290 (rank : 142)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	159	Target Neighborhood Hits	321	Shared Neighborhood Hits	67
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI43_HUMAN
NC score	0.103266 (rank : 143)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	159	Target Neighborhood Hits	341	Shared Neighborhood Hits	65
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI52_HUMAN
NC score	0.103083 (rank : 144)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	159	Target Neighborhood Hits	213	Shared Neighborhood Hits	56
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRIM6_MOUSE
NC score	0.103021 (rank : 145)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	159	Target Neighborhood Hits	451	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

RN123_MOUSE
NC score	0.102550 (rank : 146)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	159	Target Neighborhood Hits	174	Shared Neighborhood Hits	54
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRI25_HUMAN
NC score	0.102540 (rank : 147)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	159	Target Neighborhood Hits	472	Shared Neighborhood Hits	70
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRIM6_HUMAN
NC score	0.101270 (rank : 148)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	159	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI10_MOUSE
NC score	0.101198 (rank : 149)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	159	Target Neighborhood Hits	285	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI68_HUMAN
NC score	0.100792 (rank : 150)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	159	Target Neighborhood Hits	267	Shared Neighborhood Hits	62
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

RO52_MOUSE
NC score	0.098904 (rank : 151)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	159	Target Neighborhood Hits	360	Shared Neighborhood Hits	69
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

PCGF6_HUMAN
NC score	0.098457 (rank : 152)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	159	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
NC score	0.098280 (rank : 153)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI68_MOUSE
NC score	0.098170 (rank : 154)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	159	Target Neighborhood Hits	356	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI47_HUMAN
NC score	0.095993 (rank : 155)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	159	Target Neighborhood Hits	286	Shared Neighborhood Hits	60
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI11_HUMAN
NC score	0.095898 (rank : 156)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	159	Target Neighborhood Hits	316	Shared Neighborhood Hits	63
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
NC score	0.095220 (rank : 157)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	159	Target Neighborhood Hits	329	Shared Neighborhood Hits	63
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI17_HUMAN
NC score	0.094533 (rank : 158)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	159	Target Neighborhood Hits	318	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

PZRN4_HUMAN
NC score	0.094322 (rank : 159)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	159	Target Neighborhood Hits	438	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRI34_HUMAN
NC score	0.093328 (rank : 160)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	159	Target Neighborhood Hits	416	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

VPS11_MOUSE
NC score	0.093173 (rank : 161)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	159	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	Q91W86, Q9DBX8	Gene names	Vps11
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11.

VPS11_HUMAN
NC score	0.092391 (rank : 162)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	159	Target Neighborhood Hits	86	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H270, Q8WY89, Q96EP8, Q9H6D9, Q9HCS6	Gene names	VPS11, RNF108
Domain Architecture
Description	Vacuolar protein sorting-associated protein 11 (hVPS11) (RING finger protein 108).

TRI37_HUMAN
NC score	0.090959 (rank : 163)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

RFWD2_MOUSE
NC score	0.090856 (rank : 164)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	159	Target Neighborhood Hits	535	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

LNX2_MOUSE
NC score	0.090823 (rank : 165)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	159	Target Neighborhood Hits	407	Shared Neighborhood Hits	83
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

TRI37_MOUSE
NC score	0.090669 (rank : 166)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	159	Target Neighborhood Hits	316	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI48_HUMAN
NC score	0.090623 (rank : 167)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	159	Target Neighborhood Hits	192	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRIM7_MOUSE
NC score	0.090593 (rank : 168)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	159	Target Neighborhood Hits	358	Shared Neighborhood Hits	58
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

RFWD2_HUMAN
NC score	0.090579 (rank : 169)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	159	Target Neighborhood Hits	518	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

TRI49_HUMAN
NC score	0.090234 (rank : 170)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	159	Target Neighborhood Hits	199	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI38_HUMAN
NC score	0.089736 (rank : 171)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	159	Target Neighborhood Hits	373	Shared Neighborhood Hits	51
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

BRCA1_HUMAN
NC score	0.089726 (rank : 172)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	159	Target Neighborhood Hits	381	Shared Neighborhood Hits	67
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRIM7_HUMAN
NC score	0.089336 (rank : 173)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	159	Target Neighborhood Hits	336	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI15_HUMAN
NC score	0.089029 (rank : 174)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	159	Target Neighborhood Hits	395	Shared Neighborhood Hits	61
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_MOUSE
NC score	0.087900 (rank : 175)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	159	Target Neighborhood Hits	620	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI47_MOUSE
NC score	0.087059 (rank : 176)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	159	Target Neighborhood Hits	295	Shared Neighborhood Hits	59
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

RBBP6_MOUSE
NC score	0.086432 (rank : 177)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	159	Target Neighborhood Hits	1014	Shared Neighborhood Hits	72
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

MYCB2_MOUSE
NC score	0.086406 (rank : 178)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ZN179_HUMAN
NC score	0.085908 (rank : 179)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	159	Target Neighborhood Hits	178	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

MYCB2_HUMAN
NC score	0.085577 (rank : 180)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	159	Target Neighborhood Hits	390	Shared Neighborhood Hits	43
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MGRN1_HUMAN
NC score	0.085086 (rank : 181)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	159	Target Neighborhood Hits	192	Shared Neighborhood Hits	47
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

TRI34_MOUSE
NC score	0.084872 (rank : 182)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	159	Target Neighborhood Hits	332	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI32_HUMAN
NC score	0.084538 (rank : 183)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	159	Target Neighborhood Hits	264	Shared Neighborhood Hits	52
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.084305 (rank : 184)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	159	Target Neighborhood Hits	271	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI56_HUMAN
NC score	0.084277 (rank : 185)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	159	Target Neighborhood Hits	339	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI27_HUMAN
NC score	0.084209 (rank : 186)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	159	Target Neighborhood Hits	273	Shared Neighborhood Hits	54
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.083807 (rank : 187)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	159	Target Neighborhood Hits	261	Shared Neighborhood Hits	52
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

RNF39_HUMAN
NC score	0.083241 (rank : 188)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	159	Target Neighborhood Hits	200	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

LNX2_HUMAN
NC score	0.082737 (rank : 189)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	159	Target Neighborhood Hits	389	Shared Neighborhood Hits	77
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

BRCA1_MOUSE
NC score	0.082421 (rank : 190)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	159	Target Neighborhood Hits	436	Shared Neighborhood Hits	66
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RN146_HUMAN
NC score	0.081985 (rank : 191)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	159	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.080286 (rank : 192)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	159	Target Neighborhood Hits	161	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRI54_HUMAN
NC score	0.079957 (rank : 193)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	159	Target Neighborhood Hits	209	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI41_HUMAN
NC score	0.079327 (rank : 194)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	159	Target Neighborhood Hits	349	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI54_MOUSE
NC score	0.078132 (rank : 195)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	159	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

MGRN1_MOUSE
NC score	0.078114 (rank : 196)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	159	Target Neighborhood Hits	149	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

TRI63_HUMAN
NC score	0.077642 (rank : 197)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	159	Target Neighborhood Hits	298	Shared Neighborhood Hits	38
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRAF6_MOUSE
NC score	0.077594 (rank : 198)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	61
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI63_MOUSE
NC score	0.077164 (rank : 199)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	159	Target Neighborhood Hits	240	Shared Neighborhood Hits	38
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRAF6_HUMAN
NC score	0.075560 (rank : 200)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	159	Target Neighborhood Hits	267	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

LNX1_HUMAN
NC score	0.075002 (rank : 201)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	159	Target Neighborhood Hits	379	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
NC score	0.073883 (rank : 202)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	159	Target Neighborhood Hits	377	Shared Neighborhood Hits	72
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRI55_HUMAN
NC score	0.072802 (rank : 203)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	159	Target Neighborhood Hits	292	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

RAG1_HUMAN
NC score	0.072583 (rank : 204)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	159	Target Neighborhood Hits	203	Shared Neighborhood Hits	52
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
NC score	0.068941 (rank : 205)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	159	Target Neighborhood Hits	189	Shared Neighborhood Hits	52
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI56_MOUSE
NC score	0.068892 (rank : 206)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	159	Target Neighborhood Hits	255	Shared Neighborhood Hits	57
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

SMRA3_HUMAN
NC score	0.066973 (rank : 207)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	159	Target Neighborhood Hits	265	Shared Neighborhood Hits	70
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI18_HUMAN
NC score	0.066286 (rank : 208)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	159	Target Neighborhood Hits	307	Shared Neighborhood Hits	53
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
NC score	0.066026 (rank : 209)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	159	Target Neighborhood Hits	292	Shared Neighborhood Hits	54
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

SMRA3_MOUSE
NC score	0.065422 (rank : 210)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	159	Target Neighborhood Hits	267	Shared Neighborhood Hits	72
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

RBBP6_HUMAN
NC score	0.064069 (rank : 211)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	159	Target Neighborhood Hits	1135	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRIM1_MOUSE
NC score	0.062024 (rank : 212)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	159	Target Neighborhood Hits	361	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM1_HUMAN
NC score	0.061519 (rank : 213)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	159	Target Neighborhood Hits	345	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

MEFV_HUMAN
NC score	0.060940 (rank : 214)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	159	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

RN169_HUMAN
NC score	0.060810 (rank : 215)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	159	Target Neighborhood Hits	203	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TRI44_MOUSE
NC score	0.058910 (rank : 216)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	159	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI14_MOUSE
NC score	0.058603 (rank : 217)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	159	Target Neighborhood Hits	137	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI44_HUMAN
NC score	0.057962 (rank : 218)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	159	Target Neighborhood Hits	393	Shared Neighborhood Hits	24
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

RN183_HUMAN
NC score	0.056258 (rank : 219)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

BSPRY_MOUSE
NC score	0.055539 (rank : 220)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	159	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

R113A_HUMAN
NC score	0.055497 (rank : 221)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	159	Target Neighborhood Hits	177	Shared Neighborhood Hits	44
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TRI14_HUMAN
NC score	0.055445 (rank : 222)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	21
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

R113B_HUMAN
NC score	0.055234 (rank : 223)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	159	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RNF37_MOUSE
NC score	0.054283 (rank : 224)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	159	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

TRI16_HUMAN
NC score	0.053957 (rank : 225)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	159	Target Neighborhood Hits	231	Shared Neighborhood Hits	22
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_MOUSE
NC score	0.053497 (rank : 226)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	159	Target Neighborhood Hits	306	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

RFPL3_HUMAN
NC score	0.053325 (rank : 227)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	159	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

BSPRY_HUMAN
NC score	0.053234 (rank : 228)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	159	Target Neighborhood Hits	115	Shared Neighborhood Hits	18
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRAF7_HUMAN
NC score	0.053207 (rank : 229)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	159	Target Neighborhood Hits	482	Shared Neighborhood Hits	53
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF4_HUMAN
NC score	0.052466 (rank : 230)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	159	Target Neighborhood Hits	373	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

RFPL2_HUMAN
NC score	0.052431 (rank : 231)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	159	Target Neighborhood Hits	126	Shared Neighborhood Hits	26
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

MEFV_MOUSE
NC score	0.052217 (rank : 232)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	159	Target Neighborhood Hits	236	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRAF7_MOUSE
NC score	0.052197 (rank : 233)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	159	Target Neighborhood Hits	470	Shared Neighborhood Hits	48
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI29_HUMAN
NC score	0.051522 (rank : 234)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	159	Target Neighborhood Hits	273	Shared Neighborhood Hits	21
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRAF5_MOUSE
NC score	0.051208 (rank : 235)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	159	Target Neighborhood Hits	355	Shared Neighborhood Hits	46
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

RFPL1_HUMAN
NC score	0.051105 (rank : 236)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	159	Target Neighborhood Hits	119	Shared Neighborhood Hits	24
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

ZN294_MOUSE
NC score	0.051015 (rank : 237)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	159	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

TRI16_MOUSE
NC score	0.050885 (rank : 238)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	159	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

ZN294_HUMAN
NC score	0.050593 (rank : 239)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	159	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	O94822, Q9H8M4, Q9NUY5, Q9P0E9	Gene names	ZNF294, C21orf10, C21orf98, KIAA0714
Domain Architecture
Description	Zinc finger protein 294.

UHRF2_HUMAN
NC score	0.050190 (rank : 240)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	159	Target Neighborhood Hits	269	Shared Neighborhood Hits	49
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

ERMAP_HUMAN
NC score	0.050019 (rank : 241)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	159	Target Neighborhood Hits	155	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI46_MOUSE
NC score	0.050018 (rank : 242)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	159	Target Neighborhood Hits	287	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

PRP40_MOUSE
NC score	0.049793 (rank : 243)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	159	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

NFX1_HUMAN
NC score	0.043179 (rank : 244)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	159	Target Neighborhood Hits	405	Shared Neighborhood Hits	20
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

GPTC8_HUMAN
NC score	0.042081 (rank : 245)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	159	Target Neighborhood Hits	366	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

LEO1_MOUSE
NC score	0.034057 (rank : 246)	θ value	0.0961366 (rank : 65)
Query Neighborhood Hits	159	Target Neighborhood Hits	946	Shared Neighborhood Hits	20
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NUCKS_HUMAN
NC score	0.028402 (rank : 247)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	159	Target Neighborhood Hits	143	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

IPP2_MOUSE
NC score	0.028179 (rank : 248)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	159	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

DMP1_MOUSE
NC score	0.026609 (rank : 249)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	159	Target Neighborhood Hits	498	Shared Neighborhood Hits	17
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

NPBL_MOUSE
NC score	0.024826 (rank : 250)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	159	Target Neighborhood Hits	1041	Shared Neighborhood Hits	24
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ENL_HUMAN
NC score	0.021449 (rank : 251)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	159	Target Neighborhood Hits	305	Shared Neighborhood Hits	11
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

MARH2_MOUSE
NC score	0.020621 (rank : 252)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	159	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M02, Q8C4Q5	Gene names	March2
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 2 (Membrane-associated RING-CH protein II) (MARCH-II).

TGON2_HUMAN
NC score	0.020542 (rank : 253)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	159	Target Neighborhood Hits	1037	Shared Neighborhood Hits	29
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

HN1_HUMAN
NC score	0.019761 (rank : 254)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	159	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK76, Q53FG7, Q7Z2D2, Q7Z2F0	Gene names	HN1, ARM2
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1 protein (Androgen-regulated protein 2).

PHF7_HUMAN
NC score	0.019429 (rank : 255)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	159	Target Neighborhood Hits	71	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

SRRM2_HUMAN
NC score	0.018927 (rank : 256)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	159	Target Neighborhood Hits	1296	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MYPT1_MOUSE
NC score	0.017585 (rank : 257)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	159	Target Neighborhood Hits	539	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MYPT1_HUMAN
NC score	0.016648 (rank : 258)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	159	Target Neighborhood Hits	723	Shared Neighborhood Hits	14
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

AP3B2_HUMAN
NC score	0.015701 (rank : 259)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	159	Target Neighborhood Hits	246	Shared Neighborhood Hits	11
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

AKAP2_HUMAN
NC score	0.014050 (rank : 260)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	159	Target Neighborhood Hits	507	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

UB7I1_HUMAN
NC score	0.013857 (rank : 261)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	159	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

PKHA4_MOUSE
NC score	0.012682 (rank : 262)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	159	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CRNL1_MOUSE
NC score	0.012344 (rank : 263)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	159	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

MAGL2_MOUSE
NC score	0.011011 (rank : 264)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	159	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ04	Gene names	Magel2
Domain Architecture
Description	MAGE-like protein 2 (Protein nS7).

DLGP4_HUMAN
NC score	0.010327 (rank : 265)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	159	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

HRX_HUMAN
NC score	0.009959 (rank : 266)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	159	Target Neighborhood Hits	825	Shared Neighborhood Hits	20
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CACB2_MOUSE
NC score	0.009753 (rank : 267)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	159	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

M3K1_MOUSE
NC score	0.009271 (rank : 268)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	159	Target Neighborhood Hits	952	Shared Neighborhood Hits	16
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

ETV6_HUMAN
NC score	0.008603 (rank : 269)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	159	Target Neighborhood Hits	120	Shared Neighborhood Hits	2
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

TACC2_MOUSE
NC score	0.008510 (rank : 270)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	159	Target Neighborhood Hits	774	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

SLY_MOUSE
NC score	0.007983 (rank : 271)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	159	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

FGD5_MOUSE
NC score	0.007681 (rank : 272)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	159	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

IRX6_HUMAN
NC score	0.006314 (rank : 273)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	159	Target Neighborhood Hits	262	Shared Neighborhood Hits	3
SwissProt Accessions	P78412, Q7Z2K0	Gene names	IRX6, IRX7, IRXB3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3).

BAT2_MOUSE
NC score	0.006225 (rank : 274)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	159	Target Neighborhood Hits	947	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CSKI2_HUMAN
NC score	0.005463 (rank : 275)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	159	Target Neighborhood Hits	747	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ATS19_MOUSE
NC score	0.003287 (rank : 276)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	159	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

NFM_MOUSE
NC score	0.003112 (rank : 277)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	159	Target Neighborhood Hits	1159	Shared Neighborhood Hits	19
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

WEE1B_HUMAN
NC score	0.002248 (rank : 278)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	159	Target Neighborhood Hits	836	Shared Neighborhood Hits	8
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

LRCH4_HUMAN
NC score	0.001224 (rank : 279)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	159	Target Neighborhood Hits	305	Shared Neighborhood Hits	2
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

ZN592_HUMAN
NC score	-0.002971 (rank : 280)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	159	Target Neighborhood Hits	762	Shared Neighborhood Hits	5
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

M4K1_HUMAN
NC score	-0.004247 (rank : 281)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	159	Target Neighborhood Hits	884	Shared Neighborhood Hits	5
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).