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Network neighborhood for query Sequence : TRAF7_MOUSE

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TRAF7_MOUSE
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRAF7_HUMAN
θ value	0 (rank : 1)	NC score	0.997976 (rank : 2)
Query Neighborhood Hits	470	Target Neighborhood Hits	482	Shared Neighborhood Hits	462
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	470	Target Neighborhood Hits	470	Shared Neighborhood Hits	470
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

FBXW7_HUMAN
θ value	1.16434e-31 (rank : 3)	NC score	0.830931 (rank : 6)
Query Neighborhood Hits	470	Target Neighborhood Hits	433	Shared Neighborhood Hits	253
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	1.16434e-31 (rank : 4)	NC score	0.833231 (rank : 4)
Query Neighborhood Hits	470	Target Neighborhood Hits	365	Shared Neighborhood Hits	252
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBW1B_HUMAN
θ value	3.74554e-30 (rank : 5)	NC score	0.834474 (rank : 3)
Query Neighborhood Hits	470	Target Neighborhood Hits	327	Shared Neighborhood Hits	248
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBW1A_HUMAN
θ value	2.42779e-29 (rank : 6)	NC score	0.832984 (rank : 5)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

LIS1_HUMAN
θ value	6.18819e-25 (rank : 7)	NC score	0.822445 (rank : 7)
Query Neighborhood Hits	470	Target Neighborhood Hits	333	Shared Neighborhood Hits	250
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
θ value	6.18819e-25 (rank : 8)	NC score	0.822419 (rank : 8)
Query Neighborhood Hits	470	Target Neighborhood Hits	336	Shared Neighborhood Hits	252
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

WDR5_HUMAN
θ value	2.69047e-20 (rank : 9)	NC score	0.796858 (rank : 12)
Query Neighborhood Hits	470	Target Neighborhood Hits	341	Shared Neighborhood Hits	252
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
θ value	2.69047e-20 (rank : 10)	NC score	0.796858 (rank : 13)
Query Neighborhood Hits	470	Target Neighborhood Hits	341	Shared Neighborhood Hits	252
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

WDR69_HUMAN
θ value	1.13037e-18 (rank : 11)	NC score	0.809830 (rank : 9)
Query Neighborhood Hits	470	Target Neighborhood Hits	324	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

WDR57_MOUSE
θ value	1.24977e-17 (rank : 12)	NC score	0.795074 (rank : 15)
Query Neighborhood Hits	470	Target Neighborhood Hits	323	Shared Neighborhood Hits	253
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

WDR57_HUMAN
θ value	2.13179e-17 (rank : 13)	NC score	0.795531 (rank : 14)
Query Neighborhood Hits	470	Target Neighborhood Hits	322	Shared Neighborhood Hits	253
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

ZF106_HUMAN
θ value	4.74913e-17 (rank : 14)	NC score	0.651580 (rank : 131)
Query Neighborhood Hits	470	Target Neighborhood Hits	470	Shared Neighborhood Hits	185
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

NLE1_HUMAN
θ value	3.07829e-16 (rank : 15)	NC score	0.790134 (rank : 17)
Query Neighborhood Hits	470	Target Neighborhood Hits	334	Shared Neighborhood Hits	253
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

NLE1_MOUSE
θ value	4.02038e-16 (rank : 16)	NC score	0.790761 (rank : 16)
Query Neighborhood Hits	470	Target Neighborhood Hits	332	Shared Neighborhood Hits	253
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

WD51A_MOUSE
θ value	2.60593e-15 (rank : 17)	NC score	0.788105 (rank : 18)
Query Neighborhood Hits	470	Target Neighborhood Hits	342	Shared Neighborhood Hits	254
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

KI21A_HUMAN
θ value	4.44505e-15 (rank : 18)	NC score	0.368758 (rank : 248)
Query Neighborhood Hits	470	Target Neighborhood Hits	1543	Shared Neighborhood Hits	278
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

WD51A_HUMAN
θ value	2.88119e-14 (rank : 19)	NC score	0.785621 (rank : 19)
Query Neighborhood Hits	470	Target Neighborhood Hits	337	Shared Neighborhood Hits	252
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

KI21B_HUMAN
θ value	1.86753e-13 (rank : 20)	NC score	0.389999 (rank : 236)
Query Neighborhood Hits	470	Target Neighborhood Hits	1017	Shared Neighborhood Hits	252
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

PLRG1_HUMAN
θ value	3.18553e-13 (rank : 21)	NC score	0.803833 (rank : 10)
Query Neighborhood Hits	470	Target Neighborhood Hits	318	Shared Neighborhood Hits	250
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

SPG16_HUMAN
θ value	1.2105e-12 (rank : 22)	NC score	0.780429 (rank : 24)
Query Neighborhood Hits	470	Target Neighborhood Hits	361	Shared Neighborhood Hits	255
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

ZF106_MOUSE
θ value	1.2105e-12 (rank : 23)	NC score	0.639811 (rank : 138)
Query Neighborhood Hits	470	Target Neighborhood Hits	472	Shared Neighborhood Hits	194
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

PLRG1_MOUSE
θ value	1.58096e-12 (rank : 24)	NC score	0.801937 (rank : 11)
Query Neighborhood Hits	470	Target Neighborhood Hits	308	Shared Neighborhood Hits	248
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

KI21A_MOUSE
θ value	2.69671e-12 (rank : 25)	NC score	0.364149 (rank : 251)
Query Neighborhood Hits	470	Target Neighborhood Hits	1317	Shared Neighborhood Hits	256
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

TBL1Y_HUMAN
θ value	3.52202e-12 (rank : 26)	NC score	0.741045 (rank : 64)
Query Neighborhood Hits	470	Target Neighborhood Hits	331	Shared Neighborhood Hits	245
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

PRP4_HUMAN
θ value	6.00763e-12 (rank : 27)	NC score	0.783037 (rank : 22)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	249
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

PRP4_MOUSE
θ value	7.84624e-12 (rank : 28)	NC score	0.782705 (rank : 23)
Query Neighborhood Hits	470	Target Neighborhood Hits	308	Shared Neighborhood Hits	247
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

WDR48_HUMAN
θ value	7.84624e-12 (rank : 29)	NC score	0.777526 (rank : 26)
Query Neighborhood Hits	470	Target Neighborhood Hits	291	Shared Neighborhood Hits	241
SwissProt Accessions	Q8TAF3, Q63HJ2, Q658Y1, Q8N3Z1, Q9NSK8, Q9P279	Gene names	WDR48, KIAA1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48 (WD repeat endosomal protein) (p80).

KI21B_MOUSE
θ value	1.02475e-11 (rank : 30)	NC score	0.380975 (rank : 239)
Query Neighborhood Hits	470	Target Neighborhood Hits	997	Shared Neighborhood Hits	254
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

SPG16_MOUSE
θ value	1.02475e-11 (rank : 31)	NC score	0.775277 (rank : 29)
Query Neighborhood Hits	470	Target Neighborhood Hits	377	Shared Neighborhood Hits	250
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

WDR61_MOUSE
θ value	1.02475e-11 (rank : 32)	NC score	0.774093 (rank : 32)
Query Neighborhood Hits	470	Target Neighborhood Hits	331	Shared Neighborhood Hits	250
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WD51B_HUMAN
θ value	1.33837e-11 (rank : 33)	NC score	0.775067 (rank : 30)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	253
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WDR61_HUMAN
θ value	1.33837e-11 (rank : 34)	NC score	0.773454 (rank : 33)
Query Neighborhood Hits	470	Target Neighborhood Hits	334	Shared Neighborhood Hits	251
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WDR48_MOUSE
θ value	1.74796e-11 (rank : 35)	NC score	0.776261 (rank : 27)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	242
SwissProt Accessions	Q8BH57, Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0	Gene names	Wdr48, Kiaa1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48.

TBL1R_HUMAN
θ value	3.89403e-11 (rank : 36)	NC score	0.741181 (rank : 63)
Query Neighborhood Hits	470	Target Neighborhood Hits	327	Shared Neighborhood Hits	245
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
θ value	3.89403e-11 (rank : 37)	NC score	0.741033 (rank : 65)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	245
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBLX_MOUSE
θ value	3.89403e-11 (rank : 38)	NC score	0.740448 (rank : 66)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	245
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

WDR12_MOUSE
θ value	3.89403e-11 (rank : 39)	NC score	0.761063 (rank : 45)
Query Neighborhood Hits	470	Target Neighborhood Hits	301	Shared Neighborhood Hits	240
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

TRAF4_HUMAN
θ value	5.08577e-11 (rank : 40)	NC score	0.278539 (rank : 286)
Query Neighborhood Hits	470	Target Neighborhood Hits	373	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TBL1X_HUMAN
θ value	6.64225e-11 (rank : 41)	NC score	0.739323 (rank : 70)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	245
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

TRAF4_MOUSE
θ value	8.67504e-11 (rank : 42)	NC score	0.257259 (rank : 295)
Query Neighborhood Hits	470	Target Neighborhood Hits	338	Shared Neighborhood Hits	100
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

STRN3_HUMAN
θ value	1.133e-10 (rank : 43)	NC score	0.677141 (rank : 113)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	228
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

TAF5L_MOUSE
θ value	1.47974e-10 (rank : 44)	NC score	0.766236 (rank : 39)
Query Neighborhood Hits	470	Target Neighborhood Hits	337	Shared Neighborhood Hits	252
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

WDR31_MOUSE
θ value	1.47974e-10 (rank : 45)	NC score	0.764630 (rank : 42)
Query Neighborhood Hits	470	Target Neighborhood Hits	287	Shared Neighborhood Hits	239
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

FAN_HUMAN
θ value	1.9326e-10 (rank : 46)	NC score	0.654438 (rank : 130)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	240
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

FZR_MOUSE
θ value	1.9326e-10 (rank : 47)	NC score	0.724994 (rank : 86)
Query Neighborhood Hits	470	Target Neighborhood Hits	283	Shared Neighborhood Hits	234
SwissProt Accessions	Q9R1K5	Gene names	Fzr1, Fyr, Fzr
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog).

GBLP_HUMAN
θ value	1.9326e-10 (rank : 48)	NC score	0.785241 (rank : 20)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	250
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
θ value	1.9326e-10 (rank : 49)	NC score	0.785241 (rank : 21)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	250
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

TRAF5_HUMAN
θ value	1.9326e-10 (rank : 50)	NC score	0.276729 (rank : 287)
Query Neighborhood Hits	470	Target Neighborhood Hits	396	Shared Neighborhood Hits	126
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

FZR_HUMAN
θ value	2.52405e-10 (rank : 51)	NC score	0.723358 (rank : 88)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	234
SwissProt Accessions	Q9UM11, O75869, Q86U66, Q96NW8, Q9UI96, Q9ULH8, Q9UM10, Q9UNQ1, Q9Y2T8	Gene names	FZR1, CDH1, FYR, FZR, KIAA1242
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein 1).

KTNB1_HUMAN
θ value	2.52405e-10 (rank : 52)	NC score	0.769548 (rank : 34)
Query Neighborhood Hits	470	Target Neighborhood Hits	349	Shared Neighborhood Hits	254
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
θ value	2.52405e-10 (rank : 53)	NC score	0.769423 (rank : 35)
Query Neighborhood Hits	470	Target Neighborhood Hits	356	Shared Neighborhood Hits	254
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

TRAF5_MOUSE
θ value	2.52405e-10 (rank : 54)	NC score	0.287623 (rank : 283)
Query Neighborhood Hits	470	Target Neighborhood Hits	355	Shared Neighborhood Hits	138
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

STRN3_MOUSE
θ value	3.29651e-10 (rank : 55)	NC score	0.673473 (rank : 116)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	226
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

TAF5L_HUMAN
θ value	3.29651e-10 (rank : 56)	NC score	0.767209 (rank : 38)
Query Neighborhood Hits	470	Target Neighborhood Hits	330	Shared Neighborhood Hits	252
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

WDR12_HUMAN
θ value	3.29651e-10 (rank : 57)	NC score	0.761710 (rank : 43)
Query Neighborhood Hits	470	Target Neighborhood Hits	300	Shared Neighborhood Hits	238
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

WDR47_MOUSE
θ value	3.29651e-10 (rank : 58)	NC score	0.721472 (rank : 91)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

COPA_HUMAN
θ value	4.30538e-10 (rank : 59)	NC score	0.755837 (rank : 51)
Query Neighborhood Hits	470	Target Neighborhood Hits	297	Shared Neighborhood Hits	236
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

TRAF3_HUMAN
θ value	4.30538e-10 (rank : 60)	NC score	0.252174 (rank : 297)
Query Neighborhood Hits	470	Target Neighborhood Hits	463	Shared Neighborhood Hits	125
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

APAF_HUMAN
θ value	5.62301e-10 (rank : 61)	NC score	0.748206 (rank : 57)
Query Neighborhood Hits	470	Target Neighborhood Hits	334	Shared Neighborhood Hits	250
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

WDR47_HUMAN
θ value	5.62301e-10 (rank : 62)	NC score	0.720915 (rank : 92)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	220
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

PZRN3_MOUSE
θ value	7.34386e-10 (rank : 63)	NC score	0.216641 (rank : 321)
Query Neighborhood Hits	470	Target Neighborhood Hits	447	Shared Neighborhood Hits	147
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TAF5_MOUSE
θ value	7.34386e-10 (rank : 64)	NC score	0.769419 (rank : 36)
Query Neighborhood Hits	470	Target Neighborhood Hits	366	Shared Neighborhood Hits	255
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TBL3_HUMAN
θ value	7.34386e-10 (rank : 65)	NC score	0.776120 (rank : 28)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	236
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

GBB4_HUMAN
θ value	9.59137e-10 (rank : 66)	NC score	0.741246 (rank : 62)
Query Neighborhood Hits	470	Target Neighborhood Hits	288	Shared Neighborhood Hits	241
SwissProt Accessions	Q9HAV0	Gene names	GNB4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

PRP17_MOUSE
θ value	9.59137e-10 (rank : 67)	NC score	0.734885 (rank : 78)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	231
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

A16L1_HUMAN
θ value	1.25267e-09 (rank : 68)	NC score	0.708997 (rank : 101)
Query Neighborhood Hits	470	Target Neighborhood Hits	664	Shared Neighborhood Hits	257
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

APAF_MOUSE
θ value	1.63604e-09 (rank : 69)	NC score	0.748915 (rank : 53)
Query Neighborhood Hits	470	Target Neighborhood Hits	343	Shared Neighborhood Hits	251
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

PLAP_HUMAN
θ value	1.63604e-09 (rank : 70)	NC score	0.740148 (rank : 68)
Query Neighborhood Hits	470	Target Neighborhood Hits	266	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

TAF5_HUMAN
θ value	1.63604e-09 (rank : 71)	NC score	0.768568 (rank : 37)
Query Neighborhood Hits	470	Target Neighborhood Hits	352	Shared Neighborhood Hits	255
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

PRP17_HUMAN
θ value	2.13673e-09 (rank : 72)	NC score	0.734158 (rank : 79)
Query Neighborhood Hits	470	Target Neighborhood Hits	297	Shared Neighborhood Hits	232
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

TEP1_HUMAN
θ value	2.13673e-09 (rank : 73)	NC score	0.707739 (rank : 102)
Query Neighborhood Hits	470	Target Neighborhood Hits	371	Shared Neighborhood Hits	251
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

PZRN3_HUMAN
θ value	2.79066e-09 (rank : 74)	NC score	0.214960 (rank : 326)
Query Neighborhood Hits	470	Target Neighborhood Hits	461	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

FAN_MOUSE
θ value	3.64472e-09 (rank : 75)	NC score	0.637942 (rank : 139)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	230
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

U3IP2_MOUSE
θ value	3.64472e-09 (rank : 76)	NC score	0.761133 (rank : 44)
Query Neighborhood Hits	470	Target Neighborhood Hits	312	Shared Neighborhood Hits	234
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

GBB4_MOUSE
θ value	4.76016e-09 (rank : 77)	NC score	0.740176 (rank : 67)
Query Neighborhood Hits	470	Target Neighborhood Hits	283	Shared Neighborhood Hits	239
SwissProt Accessions	P29387, Q3TJJ1, Q8R475, Q9JHX8	Gene names	Gnb4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

COPB2_HUMAN
θ value	6.21693e-09 (rank : 78)	NC score	0.748624 (rank : 54)
Query Neighborhood Hits	470	Target Neighborhood Hits	315	Shared Neighborhood Hits	245
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

COPB2_MOUSE
θ value	6.21693e-09 (rank : 79)	NC score	0.748486 (rank : 56)
Query Neighborhood Hits	470	Target Neighborhood Hits	315	Shared Neighborhood Hits	245
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

WDR3_HUMAN
θ value	6.21693e-09 (rank : 80)	NC score	0.779954 (rank : 25)
Query Neighborhood Hits	470	Target Neighborhood Hits	334	Shared Neighborhood Hits	247
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

GBB2_HUMAN
θ value	8.11959e-09 (rank : 81)	NC score	0.737699 (rank : 74)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	242
SwissProt Accessions	P62879, P11016, P54312	Gene names	GNB2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

GBB2_MOUSE
θ value	8.11959e-09 (rank : 82)	NC score	0.737699 (rank : 75)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	242
SwissProt Accessions	P62880, P11016, P54312	Gene names	Gnb2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

WD51B_MOUSE
θ value	8.11959e-09 (rank : 83)	NC score	0.774817 (rank : 31)
Query Neighborhood Hits	470	Target Neighborhood Hits	321	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

FBXW2_MOUSE
θ value	1.06045e-08 (rank : 84)	NC score	0.756278 (rank : 50)
Query Neighborhood Hits	470	Target Neighborhood Hits	249	Shared Neighborhood Hits	220
SwissProt Accessions	Q60584	Gene names	Fbxw2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

PLAP_MOUSE
θ value	1.38499e-08 (rank : 85)	NC score	0.740059 (rank : 69)
Query Neighborhood Hits	470	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

TRAF3_MOUSE
θ value	1.38499e-08 (rank : 86)	NC score	0.248822 (rank : 301)
Query Neighborhood Hits	470	Target Neighborhood Hits	476	Shared Neighborhood Hits	129
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF6_HUMAN
θ value	1.38499e-08 (rank : 87)	NC score	0.313558 (rank : 275)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	1.38499e-08 (rank : 88)	NC score	0.314847 (rank : 272)
Query Neighborhood Hits	470	Target Neighborhood Hits	255	Shared Neighborhood Hits	150
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

GBB3_MOUSE
θ value	1.80886e-08 (rank : 89)	NC score	0.733218 (rank : 82)
Query Neighborhood Hits	470	Target Neighborhood Hits	283	Shared Neighborhood Hits	241
SwissProt Accessions	Q61011	Gene names	Gnb3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

U3IP2_HUMAN
θ value	1.80886e-08 (rank : 90)	NC score	0.759242 (rank : 46)
Query Neighborhood Hits	470	Target Neighborhood Hits	307	Shared Neighborhood Hits	235
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

GBB3_HUMAN
θ value	3.08544e-08 (rank : 91)	NC score	0.733865 (rank : 80)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	241
SwissProt Accessions	P16520, Q9BQC0	Gene names	GNB3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

GBB5_HUMAN
θ value	3.08544e-08 (rank : 92)	NC score	0.742819 (rank : 61)
Query Neighborhood Hits	470	Target Neighborhood Hits	299	Shared Neighborhood Hits	248
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBB5_MOUSE
θ value	3.08544e-08 (rank : 93)	NC score	0.743484 (rank : 60)
Query Neighborhood Hits	470	Target Neighborhood Hits	298	Shared Neighborhood Hits	248
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBB1_HUMAN
θ value	4.0297e-08 (rank : 94)	NC score	0.738396 (rank : 72)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	238
SwissProt Accessions	P62873, P04697, P04901	Gene names	GNB1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB1_MOUSE
θ value	4.0297e-08 (rank : 95)	NC score	0.738396 (rank : 73)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	238
SwissProt Accessions	P62874, P04697, P04901	Gene names	Gnb1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

PRP19_MOUSE
θ value	4.0297e-08 (rank : 96)	NC score	0.758102 (rank : 47)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	247
SwissProt Accessions	Q99KP6, Q3TP64, Q8BKZ5, Q8BVQ4	Gene names	Prpf19, Prp19, Snev
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (Nuclear matrix protein SNEV).

PK1IP_MOUSE
θ value	5.26297e-08 (rank : 97)	NC score	0.720850 (rank : 94)
Query Neighborhood Hits	470	Target Neighborhood Hits	313	Shared Neighborhood Hits	231
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

FBXW2_HUMAN
θ value	6.87365e-08 (rank : 98)	NC score	0.752505 (rank : 52)
Query Neighborhood Hits	470	Target Neighborhood Hits	260	Shared Neighborhood Hits	221
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

WDR31_HUMAN
θ value	6.87365e-08 (rank : 99)	NC score	0.757631 (rank : 48)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	238
SwissProt Accessions	Q8NA23, Q96EG8	Gene names	WDR31
Domain Architecture
Description	WD repeat protein 31.

A16L1_MOUSE
θ value	8.97725e-08 (rank : 100)	NC score	0.688415 (rank : 109)
Query Neighborhood Hits	470	Target Neighborhood Hits	776	Shared Neighborhood Hits	260
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

STRN_HUMAN
θ value	8.97725e-08 (rank : 101)	NC score	0.660395 (rank : 126)
Query Neighborhood Hits	470	Target Neighborhood Hits	308	Shared Neighborhood Hits	230
SwissProt Accessions	O43815, Q9NP38	Gene names	STRN
Domain Architecture
Description	Striatin.

WDR37_HUMAN
θ value	8.97725e-08 (rank : 102)	NC score	0.746134 (rank : 58)
Query Neighborhood Hits	470	Target Neighborhood Hits	303	Shared Neighborhood Hits	237
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

WDR39_HUMAN
θ value	8.97725e-08 (rank : 103)	NC score	0.720043 (rank : 95)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	225
SwissProt Accessions	O76071	Gene names	WDR39, CIAO1
Domain Architecture
Description	WD repeat protein 39 (Ciao 1 protein).

PRP19_HUMAN
θ value	1.17247e-07 (rank : 104)	NC score	0.757478 (rank : 49)
Query Neighborhood Hits	470	Target Neighborhood Hits	333	Shared Neighborhood Hits	247
SwissProt Accessions	Q9UMS4	Gene names	PRPF19, NMP200, PRP19
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (hPso4).

STRN4_HUMAN
θ value	1.17247e-07 (rank : 105)	NC score	0.672916 (rank : 117)
Query Neighborhood Hits	470	Target Neighborhood Hits	325	Shared Neighborhood Hits	239
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

WDR16_MOUSE
θ value	1.53129e-07 (rank : 106)	NC score	0.700028 (rank : 105)
Query Neighborhood Hits	470	Target Neighborhood Hits	269	Shared Neighborhood Hits	227
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

WDR17_HUMAN
θ value	1.53129e-07 (rank : 107)	NC score	0.727784 (rank : 85)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	246
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

STRN4_MOUSE
θ value	2.61198e-07 (rank : 108)	NC score	0.674900 (rank : 114)
Query Neighborhood Hits	470	Target Neighborhood Hits	324	Shared Neighborhood Hits	238
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

STRN_MOUSE
θ value	2.61198e-07 (rank : 109)	NC score	0.666733 (rank : 121)
Query Neighborhood Hits	470	Target Neighborhood Hits	326	Shared Neighborhood Hits	236
SwissProt Accessions	O55106	Gene names	Strn
Domain Architecture
Description	Striatin.

RBBP7_HUMAN
θ value	7.59969e-07 (rank : 110)	NC score	0.610801 (rank : 150)
Query Neighborhood Hits	470	Target Neighborhood Hits	285	Shared Neighborhood Hits	231
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
θ value	7.59969e-07 (rank : 111)	NC score	0.610781 (rank : 151)
Query Neighborhood Hits	470	Target Neighborhood Hits	285	Shared Neighborhood Hits	231
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

SIAH2_HUMAN
θ value	7.59969e-07 (rank : 112)	NC score	0.188928 (rank : 381)
Query Neighborhood Hits	470	Target Neighborhood Hits	94	Shared Neighborhood Hits	53
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	7.59969e-07 (rank : 113)	NC score	0.188633 (rank : 382)
Query Neighborhood Hits	470	Target Neighborhood Hits	101	Shared Neighborhood Hits	53
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

PZRN4_HUMAN
θ value	9.92553e-07 (rank : 114)	NC score	0.195047 (rank : 368)
Query Neighborhood Hits	470	Target Neighborhood Hits	438	Shared Neighborhood Hits	145
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

MORG1_HUMAN
θ value	1.29631e-06 (rank : 115)	NC score	0.765189 (rank : 41)
Query Neighborhood Hits	470	Target Neighborhood Hits	280	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BRX9, Q53FT6	Gene names	MORG1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

MORG1_MOUSE
θ value	1.29631e-06 (rank : 116)	NC score	0.765437 (rank : 40)
Query Neighborhood Hits	470	Target Neighborhood Hits	281	Shared Neighborhood Hits	241
SwissProt Accessions	Q9DAJ4, Q505C2, Q8VEB7, Q99JX9, Q9D235	Gene names	Morg1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

PWP2_MOUSE
θ value	1.29631e-06 (rank : 117)	NC score	0.723346 (rank : 89)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	246
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

WDR37_MOUSE
θ value	1.29631e-06 (rank : 118)	NC score	0.744483 (rank : 59)
Query Neighborhood Hits	470	Target Neighborhood Hits	298	Shared Neighborhood Hits	235
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

TLE2_MOUSE
θ value	2.21117e-06 (rank : 119)	NC score	0.570707 (rank : 166)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	227
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

SMU1_HUMAN
θ value	2.88788e-06 (rank : 120)	NC score	0.736496 (rank : 76)
Query Neighborhood Hits	470	Target Neighborhood Hits	311	Shared Neighborhood Hits	242
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
θ value	2.88788e-06 (rank : 121)	NC score	0.736496 (rank : 77)
Query Neighborhood Hits	470	Target Neighborhood Hits	311	Shared Neighborhood Hits	242
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

TLE3_HUMAN
θ value	2.88788e-06 (rank : 122)	NC score	0.557749 (rank : 176)
Query Neighborhood Hits	470	Target Neighborhood Hits	385	Shared Neighborhood Hits	228
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

TLE3_MOUSE
θ value	2.88788e-06 (rank : 123)	NC score	0.560319 (rank : 172)
Query Neighborhood Hits	470	Target Neighborhood Hits	378	Shared Neighborhood Hits	229
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

BRWD1_HUMAN
θ value	3.77169e-06 (rank : 124)	NC score	0.666168 (rank : 122)
Query Neighborhood Hits	470	Target Neighborhood Hits	448	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRWD1_MOUSE
θ value	3.77169e-06 (rank : 125)	NC score	0.663829 (rank : 123)
Query Neighborhood Hits	470	Target Neighborhood Hits	478	Shared Neighborhood Hits	246
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

PK1IP_HUMAN
θ value	3.77169e-06 (rank : 126)	NC score	0.713877 (rank : 98)
Query Neighborhood Hits	470	Target Neighborhood Hits	277	Shared Neighborhood Hits	222
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

TLE4_HUMAN
θ value	3.77169e-06 (rank : 127)	NC score	0.557065 (rank : 178)
Query Neighborhood Hits	470	Target Neighborhood Hits	477	Shared Neighborhood Hits	230
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	3.77169e-06 (rank : 128)	NC score	0.556872 (rank : 180)
Query Neighborhood Hits	470	Target Neighborhood Hits	482	Shared Neighborhood Hits	230
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

WDR16_HUMAN
θ value	3.77169e-06 (rank : 129)	NC score	0.697286 (rank : 107)
Query Neighborhood Hits	470	Target Neighborhood Hits	275	Shared Neighborhood Hits	228
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

TLE2_HUMAN
θ value	4.92598e-06 (rank : 130)	NC score	0.569700 (rank : 167)
Query Neighborhood Hits	470	Target Neighborhood Hits	321	Shared Neighborhood Hits	229
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

WSB2_MOUSE
θ value	4.92598e-06 (rank : 131)	NC score	0.733432 (rank : 81)
Query Neighborhood Hits	470	Target Neighborhood Hits	306	Shared Neighborhood Hits	241
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

FBXW4_MOUSE
θ value	6.43352e-06 (rank : 132)	NC score	0.606860 (rank : 153)
Query Neighborhood Hits	470	Target Neighborhood Hits	205	Shared Neighborhood Hits	172
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

PWP2_HUMAN
θ value	6.43352e-06 (rank : 133)	NC score	0.719768 (rank : 96)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	246
SwissProt Accessions	Q15269, Q96A77	Gene names	PWP2H, PWP2
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

WSB2_HUMAN
θ value	6.43352e-06 (rank : 134)	NC score	0.732532 (rank : 83)
Query Neighborhood Hits	470	Target Neighborhood Hits	308	Shared Neighborhood Hits	241
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

CDC20_HUMAN
θ value	8.40245e-06 (rank : 135)	NC score	0.701476 (rank : 104)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	223
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

STRAP_HUMAN
θ value	8.40245e-06 (rank : 136)	NC score	0.720873 (rank : 93)
Query Neighborhood Hits	470	Target Neighborhood Hits	272	Shared Neighborhood Hits	225
SwissProt Accessions	Q9Y3F4, Q9UQC8	Gene names	STRAP, MAWD, UNRIP
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein) (WD-40 repeat protein PT-WD) (MAP activator with WD repeats).

WDR71_HUMAN
θ value	8.40245e-06 (rank : 137)	NC score	0.748487 (rank : 55)
Query Neighborhood Hits	470	Target Neighborhood Hits	241	Shared Neighborhood Hits	215
SwissProt Accessions	Q9BRP4, Q4G165, Q53HS9, Q7Z500, Q8TBU6, Q9HAB6	Gene names	WDR71
Domain Architecture	No domain graphic available
Description	WD repeat protein 71 (Protein G-16).

CDC20_MOUSE
θ value	1.09739e-05 (rank : 138)	NC score	0.697769 (rank : 106)
Query Neighborhood Hits	470	Target Neighborhood Hits	325	Shared Neighborhood Hits	223
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

RBBP4_HUMAN
θ value	1.09739e-05 (rank : 139)	NC score	0.611955 (rank : 149)
Query Neighborhood Hits	470	Target Neighborhood Hits	291	Shared Neighborhood Hits	231
SwissProt Accessions	Q09028, P31149, Q53H02, Q96BV9	Gene names	RBBP4, RBAP48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

RBBP4_MOUSE
θ value	1.09739e-05 (rank : 140)	NC score	0.612133 (rank : 148)
Query Neighborhood Hits	470	Target Neighborhood Hits	289	Shared Neighborhood Hits	229
SwissProt Accessions	Q60972	Gene names	Rbbp4, Rbap48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

TLE1_HUMAN
θ value	1.09739e-05 (rank : 141)	NC score	0.545354 (rank : 190)
Query Neighborhood Hits	470	Target Neighborhood Hits	485	Shared Neighborhood Hits	228
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TLE1_MOUSE
θ value	1.09739e-05 (rank : 142)	NC score	0.545036 (rank : 191)
Query Neighborhood Hits	470	Target Neighborhood Hits	491	Shared Neighborhood Hits	228
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

PEX7_HUMAN
θ value	1.43324e-05 (rank : 143)	NC score	0.707104 (rank : 103)
Query Neighborhood Hits	470	Target Neighborhood Hits	275	Shared Neighborhood Hits	229
SwissProt Accessions	O00628	Gene names	PEX7, PTS2R
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

STRAP_MOUSE
θ value	1.43324e-05 (rank : 144)	NC score	0.721976 (rank : 90)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	225
SwissProt Accessions	Q9Z1Z2	Gene names	Strap, Unrip
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein).

FBXW4_HUMAN
θ value	3.19293e-05 (rank : 145)	NC score	0.583523 (rank : 164)
Query Neighborhood Hits	470	Target Neighborhood Hits	209	Shared Neighborhood Hits	174
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

PEX7_MOUSE
θ value	3.19293e-05 (rank : 146)	NC score	0.711040 (rank : 100)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	235
SwissProt Accessions	P97865	Gene names	Pex7
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

WDHD1_HUMAN
θ value	3.19293e-05 (rank : 147)	NC score	0.567319 (rank : 169)
Query Neighborhood Hits	470	Target Neighborhood Hits	342	Shared Neighborhood Hits	193
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDR18_HUMAN
θ value	3.19293e-05 (rank : 148)	NC score	0.693942 (rank : 108)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	223
SwissProt Accessions	Q9BV38, O60390, Q9BWR2	Gene names	WDR18
Domain Architecture
Description	WD repeat protein 18.

UTP15_HUMAN
θ value	4.1701e-05 (rank : 149)	NC score	0.724225 (rank : 87)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	241
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

WDR18_MOUSE
θ value	4.1701e-05 (rank : 150)	NC score	0.674889 (rank : 115)
Query Neighborhood Hits	470	Target Neighborhood Hits	239	Shared Neighborhood Hits	213
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

WDR33_HUMAN
θ value	5.44631e-05 (rank : 151)	NC score	0.632100 (rank : 142)
Query Neighborhood Hits	470	Target Neighborhood Hits	638	Shared Neighborhood Hits	243
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

WSB1_HUMAN
θ value	5.44631e-05 (rank : 152)	NC score	0.716673 (rank : 97)
Query Neighborhood Hits	470	Target Neighborhood Hits	337	Shared Neighborhood Hits	238
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

WSB1_MOUSE
θ value	5.44631e-05 (rank : 153)	NC score	0.713688 (rank : 99)
Query Neighborhood Hits	470	Target Neighborhood Hits	313	Shared Neighborhood Hits	237
SwissProt Accessions	O54927	Gene names	Wsb1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1).

TEP1_MOUSE
θ value	0.000121331 (rank : 154)	NC score	0.672391 (rank : 118)
Query Neighborhood Hits	470	Target Neighborhood Hits	344	Shared Neighborhood Hits	243
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

UTP15_MOUSE
θ value	0.000121331 (rank : 155)	NC score	0.728987 (rank : 84)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	246
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

WDR26_HUMAN
θ value	0.000121331 (rank : 156)	NC score	0.657649 (rank : 128)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	231
SwissProt Accessions	Q9H7D7, Q86UY4	Gene names	WDR26
Domain Architecture
Description	WD repeat protein 26.

WDR26_MOUSE
θ value	0.000121331 (rank : 157)	NC score	0.657900 (rank : 127)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	231
SwissProt Accessions	Q8C6G8, Q8C4F3, Q8VDZ6	Gene names	Wdr26
Domain Architecture
Description	WD repeat protein 26.

ERCC8_MOUSE
θ value	0.000158464 (rank : 158)	NC score	0.661773 (rank : 124)
Query Neighborhood Hits	470	Target Neighborhood Hits	269	Shared Neighborhood Hits	220
SwissProt Accessions	Q8CFD5, Q3U066, Q8VDC4, Q9CWK7	Gene names	Ercc8, Ckn1, Csa
Domain Architecture	No domain graphic available
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog).

WDFY1_HUMAN
θ value	0.000158464 (rank : 159)	NC score	0.563963 (rank : 171)
Query Neighborhood Hits	470	Target Neighborhood Hits	305	Shared Neighborhood Hits	222
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

SIA1B_MOUSE
θ value	0.00020696 (rank : 160)	NC score	0.163087 (rank : 419)
Query Neighborhood Hits	470	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

SIAH1_HUMAN
θ value	0.00020696 (rank : 161)	NC score	0.165266 (rank : 416)
Query Neighborhood Hits	470	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

ZN313_MOUSE
θ value	0.00020696 (rank : 162)	NC score	0.282014 (rank : 285)
Query Neighborhood Hits	470	Target Neighborhood Hits	273	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

EMAL2_HUMAN
θ value	0.000270298 (rank : 163)	NC score	0.514720 (rank : 203)
Query Neighborhood Hits	470	Target Neighborhood Hits	217	Shared Neighborhood Hits	185
SwissProt Accessions	O95834, Q9UG50	Gene names	EML2, EMAP2, EMAPL2
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2).

RAE1L_HUMAN
θ value	0.000270298 (rank : 164)	NC score	0.592628 (rank : 160)
Query Neighborhood Hits	470	Target Neighborhood Hits	222	Shared Neighborhood Hits	194
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

RAE1L_MOUSE
θ value	0.000270298 (rank : 165)	NC score	0.593669 (rank : 158)
Query Neighborhood Hits	470	Target Neighborhood Hits	225	Shared Neighborhood Hits	196
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

TLE6_MOUSE
θ value	0.000270298 (rank : 166)	NC score	0.453894 (rank : 219)
Query Neighborhood Hits	470	Target Neighborhood Hits	178	Shared Neighborhood Hits	142
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

TRI17_HUMAN
θ value	0.000270298 (rank : 167)	NC score	0.205508 (rank : 346)
Query Neighborhood Hits	470	Target Neighborhood Hits	318	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

WDFY2_HUMAN
θ value	0.000270298 (rank : 168)	NC score	0.539957 (rank : 193)
Query Neighborhood Hits	470	Target Neighborhood Hits	332	Shared Neighborhood Hits	224
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDHD1_MOUSE
θ value	0.000270298 (rank : 169)	NC score	0.568541 (rank : 168)
Query Neighborhood Hits	470	Target Neighborhood Hits	414	Shared Neighborhood Hits	215
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

BUB3_HUMAN
θ value	0.00035302 (rank : 170)	NC score	0.571371 (rank : 165)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	183
SwissProt Accessions	O43684, O43685	Gene names	BUB3
Domain Architecture
Description	Mitotic checkpoint protein BUB3.

LNX1_HUMAN
θ value	0.00035302 (rank : 171)	NC score	0.159974 (rank : 424)
Query Neighborhood Hits	470	Target Neighborhood Hits	379	Shared Neighborhood Hits	149
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

CIR1A_MOUSE
θ value	0.000461057 (rank : 172)	NC score	0.380181 (rank : 241)
Query Neighborhood Hits	470	Target Neighborhood Hits	155	Shared Neighborhood Hits	122
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

GNB1L_HUMAN
θ value	0.000602161 (rank : 173)	NC score	0.619848 (rank : 146)
Query Neighborhood Hits	470	Target Neighborhood Hits	221	Shared Neighborhood Hits	192
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

RN125_HUMAN
θ value	0.000602161 (rank : 174)	NC score	0.261462 (rank : 291)
Query Neighborhood Hits	470	Target Neighborhood Hits	230	Shared Neighborhood Hits	142
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

SIA1A_MOUSE
θ value	0.000602161 (rank : 175)	NC score	0.160727 (rank : 422)
Query Neighborhood Hits	470	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

BUB3_MOUSE
θ value	0.000786445 (rank : 176)	NC score	0.557426 (rank : 177)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	182
SwissProt Accessions	Q9WVA3, P97397	Gene names	Bub3
Domain Architecture
Description	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5).

CSTF1_HUMAN
θ value	0.000786445 (rank : 177)	NC score	0.686798 (rank : 110)
Query Neighborhood Hits	470	Target Neighborhood Hits	266	Shared Neighborhood Hits	220
SwissProt Accessions	Q05048	Gene names	CSTF1
Domain Architecture
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

TRI17_MOUSE
θ value	0.000786445 (rank : 178)	NC score	0.192745 (rank : 372)
Query Neighborhood Hits	470	Target Neighborhood Hits	620	Shared Neighborhood Hits	165
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

WDFY2_MOUSE
θ value	0.000786445 (rank : 179)	NC score	0.531720 (rank : 198)
Query Neighborhood Hits	470	Target Neighborhood Hits	337	Shared Neighborhood Hits	224
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

WDFY3_HUMAN
θ value	0.000786445 (rank : 180)	NC score	0.365321 (rank : 249)
Query Neighborhood Hits	470	Target Neighborhood Hits	348	Shared Neighborhood Hits	195
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

CIR1A_HUMAN
θ value	0.00102713 (rank : 181)	NC score	0.397827 (rank : 230)
Query Neighborhood Hits	470	Target Neighborhood Hits	158	Shared Neighborhood Hits	129
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

GEMI5_HUMAN
θ value	0.00102713 (rank : 182)	NC score	0.548500 (rank : 184)
Query Neighborhood Hits	470	Target Neighborhood Hits	362	Shared Neighborhood Hits	228
SwissProt Accessions	Q8TEQ6, Q8WWV4, Q969W4, Q9H9K3, Q9UFI5	Gene names	GEMIN5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

LNX1_MOUSE
θ value	0.00102713 (rank : 183)	NC score	0.159863 (rank : 425)
Query Neighborhood Hits	470	Target Neighborhood Hits	377	Shared Neighborhood Hits	146
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

SCAP_HUMAN
θ value	0.00102713 (rank : 184)	NC score	0.596715 (rank : 156)
Query Neighborhood Hits	470	Target Neighborhood Hits	368	Shared Neighborhood Hits	192
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

FBXW9_HUMAN
θ value	0.00134147 (rank : 185)	NC score	0.626018 (rank : 145)
Query Neighborhood Hits	470	Target Neighborhood Hits	184	Shared Neighborhood Hits	169
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

TRI52_HUMAN
θ value	0.00134147 (rank : 186)	NC score	0.238506 (rank : 304)
Query Neighborhood Hits	470	Target Neighborhood Hits	213	Shared Neighborhood Hits	141
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

ZN313_HUMAN
θ value	0.00134147 (rank : 187)	NC score	0.271406 (rank : 289)
Query Neighborhood Hits	470	Target Neighborhood Hits	264	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRI13_HUMAN
θ value	0.00175202 (rank : 188)	NC score	0.235605 (rank : 305)
Query Neighborhood Hits	470	Target Neighborhood Hits	274	Shared Neighborhood Hits	151
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	0.00175202 (rank : 189)	NC score	0.235412 (rank : 306)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	153
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI59_HUMAN
θ value	0.00175202 (rank : 190)	NC score	0.234356 (rank : 307)
Query Neighborhood Hits	470	Target Neighborhood Hits	307	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
θ value	0.00175202 (rank : 191)	NC score	0.234295 (rank : 308)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	152
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

WDFY3_MOUSE
θ value	0.00175202 (rank : 192)	NC score	0.364389 (rank : 250)
Query Neighborhood Hits	470	Target Neighborhood Hits	332	Shared Neighborhood Hits	199
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

R113B_HUMAN
θ value	0.00228821 (rank : 193)	NC score	0.199559 (rank : 357)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TRI11_HUMAN
θ value	0.00228821 (rank : 194)	NC score	0.199704 (rank : 356)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	160
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	0.00228821 (rank : 195)	NC score	0.199379 (rank : 358)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	161
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

CSTF1_MOUSE
θ value	0.00298849 (rank : 196)	NC score	0.685090 (rank : 111)
Query Neighborhood Hits	470	Target Neighborhood Hits	266	Shared Neighborhood Hits	218
SwissProt Accessions	Q99LC2, Q3UMB8, Q8BJW1, Q9CSU8	Gene names	Cstf1
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

LYST_MOUSE
θ value	0.00298849 (rank : 197)	NC score	0.341855 (rank : 259)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	162
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

RNF41_HUMAN
θ value	0.00298849 (rank : 198)	NC score	0.258025 (rank : 294)
Query Neighborhood Hits	470	Target Neighborhood Hits	226	Shared Neighborhood Hits	146
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.00298849 (rank : 199)	NC score	0.258053 (rank : 293)
Query Neighborhood Hits	470	Target Neighborhood Hits	224	Shared Neighborhood Hits	146
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRI25_MOUSE
θ value	0.00298849 (rank : 200)	NC score	0.213917 (rank : 331)
Query Neighborhood Hits	470	Target Neighborhood Hits	446	Shared Neighborhood Hits	164
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI49_HUMAN
θ value	0.00298849 (rank : 201)	NC score	0.196054 (rank : 366)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRIM4_HUMAN
θ value	0.00298849 (rank : 202)	NC score	0.216125 (rank : 322)
Query Neighborhood Hits	470	Target Neighborhood Hits	321	Shared Neighborhood Hits	163
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

GEMI5_MOUSE
θ value	0.00390308 (rank : 203)	NC score	0.547818 (rank : 185)
Query Neighborhood Hits	470	Target Neighborhood Hits	424	Shared Neighborhood Hits	221
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

LNX2_HUMAN
θ value	0.00390308 (rank : 204)	NC score	0.152563 (rank : 431)
Query Neighborhood Hits	470	Target Neighborhood Hits	389	Shared Neighborhood Hits	148
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	0.00390308 (rank : 205)	NC score	0.153043 (rank : 430)
Query Neighborhood Hits	470	Target Neighborhood Hits	407	Shared Neighborhood Hits	151
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

RN125_MOUSE
θ value	0.00390308 (rank : 206)	NC score	0.258753 (rank : 292)
Query Neighborhood Hits	470	Target Neighborhood Hits	220	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TLE6_HUMAN
θ value	0.00390308 (rank : 207)	NC score	0.328546 (rank : 265)
Query Neighborhood Hits	470	Target Neighborhood Hits	120	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

TRI68_MOUSE
θ value	0.00390308 (rank : 208)	NC score	0.196142 (rank : 365)
Query Neighborhood Hits	470	Target Neighborhood Hits	356	Shared Neighborhood Hits	158
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRIM7_MOUSE
θ value	0.00390308 (rank : 209)	NC score	0.197672 (rank : 361)
Query Neighborhood Hits	470	Target Neighborhood Hits	358	Shared Neighborhood Hits	154
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

WDR36_HUMAN
θ value	0.00390308 (rank : 210)	NC score	0.679068 (rank : 112)
Query Neighborhood Hits	470	Target Neighborhood Hits	274	Shared Neighborhood Hits	228
SwissProt Accessions	Q8NI36, Q8N1Q2	Gene names	WDR36
Domain Architecture
Description	WD repeat protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP).

ERCC8_HUMAN
θ value	0.00509761 (rank : 211)	NC score	0.657424 (rank : 129)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	220
SwissProt Accessions	Q13216, Q6FHX5, Q96GB9	Gene names	ERCC8, CKN1, CSA
Domain Architecture
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA).

TRI50_HUMAN
θ value	0.00509761 (rank : 212)	NC score	0.214081 (rank : 330)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	164
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI62_HUMAN
θ value	0.00509761 (rank : 213)	NC score	0.195920 (rank : 367)
Query Neighborhood Hits	470	Target Neighborhood Hits	584	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	0.00509761 (rank : 214)	NC score	0.198523 (rank : 359)
Query Neighborhood Hits	470	Target Neighborhood Hits	478	Shared Neighborhood Hits	164
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

EMAL4_HUMAN
θ value	0.00665767 (rank : 215)	NC score	0.497637 (rank : 210)
Query Neighborhood Hits	470	Target Neighborhood Hits	306	Shared Neighborhood Hits	196
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

MEP50_MOUSE
θ value	0.00665767 (rank : 216)	NC score	0.608452 (rank : 152)
Query Neighborhood Hits	470	Target Neighborhood Hits	271	Shared Neighborhood Hits	218
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

NEDD1_HUMAN
θ value	0.00665767 (rank : 217)	NC score	0.565494 (rank : 170)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	213
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

PCGF6_HUMAN
θ value	0.00665767 (rank : 218)	NC score	0.138539 (rank : 447)
Query Neighborhood Hits	470	Target Neighborhood Hits	178	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI25_HUMAN
θ value	0.00665767 (rank : 219)	NC score	0.208271 (rank : 341)
Query Neighborhood Hits	470	Target Neighborhood Hits	472	Shared Neighborhood Hits	167
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRIM7_HUMAN
θ value	0.00665767 (rank : 220)	NC score	0.196502 (rank : 363)
Query Neighborhood Hits	470	Target Neighborhood Hits	336	Shared Neighborhood Hits	155
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM8_HUMAN
θ value	0.00665767 (rank : 221)	NC score	0.214650 (rank : 327)
Query Neighborhood Hits	470	Target Neighborhood Hits	650	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

WDR74_HUMAN
θ value	0.00665767 (rank : 222)	NC score	0.253963 (rank : 296)
Query Neighborhood Hits	470	Target Neighborhood Hits	94	Shared Neighborhood Hits	81
SwissProt Accessions	Q6RFH5, Q9BRC9, Q9H6X8, Q9NVY2	Gene names	WDR74, NSA1
Domain Architecture	No domain graphic available
Description	WD repeat protein 74 (NOP seven-associated protein 1).

PCGF6_MOUSE
θ value	0.00869519 (rank : 223)	NC score	0.137959 (rank : 448)
Query Neighborhood Hits	470	Target Neighborhood Hits	163	Shared Neighborhood Hits	93
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RAG1_HUMAN
θ value	0.00869519 (rank : 224)	NC score	0.206403 (rank : 345)
Query Neighborhood Hits	470	Target Neighborhood Hits	203	Shared Neighborhood Hits	123
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

TRI60_HUMAN
θ value	0.00869519 (rank : 225)	NC score	0.201197 (rank : 350)
Query Neighborhood Hits	470	Target Neighborhood Hits	357	Shared Neighborhood Hits	168
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

WDR81_MOUSE
θ value	0.00869519 (rank : 226)	NC score	0.458070 (rank : 218)
Query Neighborhood Hits	470	Target Neighborhood Hits	228	Shared Neighborhood Hits	178
SwissProt Accessions	Q5ND34, Q3TA90, Q3TUS9, Q6KAR1	Gene names	Wdr81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

WDTC1_HUMAN
θ value	0.00869519 (rank : 227)	NC score	0.531775 (rank : 197)
Query Neighborhood Hits	470	Target Neighborhood Hits	299	Shared Neighborhood Hits	218
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDTC1_MOUSE
θ value	0.00869519 (rank : 228)	NC score	0.531787 (rank : 196)
Query Neighborhood Hits	470	Target Neighborhood Hits	298	Shared Neighborhood Hits	218
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

BFAR_MOUSE
θ value	0.0113563 (rank : 229)	NC score	0.204650 (rank : 347)
Query Neighborhood Hits	470	Target Neighborhood Hits	232	Shared Neighborhood Hits	133
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

STTP1_HUMAN
θ value	0.0113563 (rank : 230)	NC score	0.521177 (rank : 201)
Query Neighborhood Hits	470	Target Neighborhood Hits	232	Shared Neighborhood Hits	200
SwissProt Accessions	Q6IA86, Q53GZ0, Q687Y8, Q8N5C2, Q96GV4, Q96PI7, Q9H9N0, Q9NV81	Gene names	STATIP1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1) (SHINC-2).

TRI39_HUMAN
θ value	0.0113563 (rank : 231)	NC score	0.191410 (rank : 375)
Query Neighborhood Hits	470	Target Neighborhood Hits	693	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.0113563 (rank : 232)	NC score	0.193081 (rank : 370)
Query Neighborhood Hits	470	Target Neighborhood Hits	691	Shared Neighborhood Hits	188
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI48_HUMAN
θ value	0.0113563 (rank : 233)	NC score	0.200458 (rank : 352)
Query Neighborhood Hits	470	Target Neighborhood Hits	192	Shared Neighborhood Hits	132
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI50_MOUSE
θ value	0.0113563 (rank : 234)	NC score	0.209985 (rank : 338)
Query Neighborhood Hits	470	Target Neighborhood Hits	326	Shared Neighborhood Hits	168
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RAG1_MOUSE
θ value	0.0148317 (rank : 235)	NC score	0.201831 (rank : 349)
Query Neighborhood Hits	470	Target Neighborhood Hits	189	Shared Neighborhood Hits	129
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI35_MOUSE
θ value	0.0148317 (rank : 236)	NC score	0.212195 (rank : 336)
Query Neighborhood Hits	470	Target Neighborhood Hits	465	Shared Neighborhood Hits	165
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI65_HUMAN
θ value	0.0148317 (rank : 237)	NC score	0.227951 (rank : 313)
Query Neighborhood Hits	470	Target Neighborhood Hits	330	Shared Neighborhood Hits	163
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM8_MOUSE
θ value	0.0148317 (rank : 238)	NC score	0.213558 (rank : 333)
Query Neighborhood Hits	470	Target Neighborhood Hits	674	Shared Neighborhood Hits	162
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

COR1B_HUMAN
θ value	0.0193708 (rank : 239)	NC score	0.362857 (rank : 252)
Query Neighborhood Hits	470	Target Neighborhood Hits	239	Shared Neighborhood Hits	182
SwissProt Accessions	Q9BR76	Gene names	CORO1B
Domain Architecture
Description	Coronin-1B (Coronin-2).

COR1B_MOUSE
θ value	0.0193708 (rank : 240)	NC score	0.359808 (rank : 253)
Query Neighborhood Hits	470	Target Neighborhood Hits	235	Shared Neighborhood Hits	176
SwissProt Accessions	Q9WUM3, Q3UEB1, Q9CVA2	Gene names	Coro1b
Domain Architecture
Description	Coronin-1B (Coronin-2).

R113A_HUMAN
θ value	0.0193708 (rank : 241)	NC score	0.191973 (rank : 374)
Query Neighborhood Hits	470	Target Neighborhood Hits	177	Shared Neighborhood Hits	119
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TRAF2_MOUSE
θ value	0.0193708 (rank : 242)	NC score	0.206845 (rank : 344)
Query Neighborhood Hits	470	Target Neighborhood Hits	394	Shared Neighborhood Hits	115
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRIM3_MOUSE
θ value	0.0193708 (rank : 243)	NC score	0.172839 (rank : 400)
Query Neighborhood Hits	470	Target Neighborhood Hits	351	Shared Neighborhood Hits	151
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

AAMP_HUMAN
θ value	0.0252991 (rank : 244)	NC score	0.739139 (rank : 71)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	235
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

BRCA1_HUMAN
θ value	0.0252991 (rank : 245)	NC score	0.207106 (rank : 343)
Query Neighborhood Hits	470	Target Neighborhood Hits	381	Shared Neighborhood Hits	166
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	0.0252991 (rank : 246)	NC score	0.200325 (rank : 353)
Query Neighborhood Hits	470	Target Neighborhood Hits	436	Shared Neighborhood Hits	168
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

STTP1_MOUSE
θ value	0.0252991 (rank : 247)	NC score	0.540133 (rank : 192)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	215
SwissProt Accessions	Q91WG4, Q3TIH5, Q3TIT0, Q8CBW6, Q9ESY7	Gene names	Statip1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1).

TRI35_HUMAN
θ value	0.0252991 (rank : 248)	NC score	0.208169 (rank : 342)
Query Neighborhood Hits	470	Target Neighborhood Hits	382	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI41_HUMAN
θ value	0.0252991 (rank : 249)	NC score	0.184524 (rank : 390)
Query Neighborhood Hits	470	Target Neighborhood Hits	349	Shared Neighborhood Hits	140
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM3_HUMAN
θ value	0.0252991 (rank : 250)	NC score	0.172141 (rank : 401)
Query Neighborhood Hits	470	Target Neighborhood Hits	357	Shared Neighborhood Hits	151
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

WDR23_MOUSE
θ value	0.0252991 (rank : 251)	NC score	0.632977 (rank : 140)
Query Neighborhood Hits	470	Target Neighborhood Hits	271	Shared Neighborhood Hits	225
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

ZN179_HUMAN
θ value	0.0252991 (rank : 252)	NC score	0.209071 (rank : 340)
Query Neighborhood Hits	470	Target Neighborhood Hits	178	Shared Neighborhood Hits	123
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

BOP1_MOUSE
θ value	0.0330416 (rank : 253)	NC score	0.531410 (rank : 199)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	214
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

RFWD2_HUMAN
θ value	0.0330416 (rank : 254)	NC score	0.650406 (rank : 133)
Query Neighborhood Hits	470	Target Neighborhood Hits	518	Shared Neighborhood Hits	367
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	0.0330416 (rank : 255)	NC score	0.650281 (rank : 134)
Query Neighborhood Hits	470	Target Neighborhood Hits	535	Shared Neighborhood Hits	369
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RNF39_HUMAN
θ value	0.0330416 (rank : 256)	NC score	0.184024 (rank : 391)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	129
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RO52_HUMAN
θ value	0.0330416 (rank : 257)	NC score	0.191397 (rank : 376)
Query Neighborhood Hits	470	Target Neighborhood Hits	419	Shared Neighborhood Hits	179
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI26_HUMAN
θ value	0.0330416 (rank : 258)	NC score	0.215240 (rank : 325)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	162
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	0.0330416 (rank : 259)	NC score	0.215697 (rank : 324)
Query Neighborhood Hits	470	Target Neighborhood Hits	339	Shared Neighborhood Hits	168
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

WDR23_HUMAN
θ value	0.0330416 (rank : 260)	NC score	0.632408 (rank : 141)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	226
SwissProt Accessions	Q8TEB1, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3, Q9H5C9	Gene names	WDR23
Domain Architecture
Description	WD repeat protein 23.

CAF1B_MOUSE
θ value	0.0431538 (rank : 261)	NC score	0.630587 (rank : 143)
Query Neighborhood Hits	470	Target Neighborhood Hits	385	Shared Neighborhood Hits	231
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

SEC13_HUMAN
θ value	0.0431538 (rank : 262)	NC score	0.497234 (rank : 212)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	166
SwissProt Accessions	P55735, Q9BRM6, Q9BUG7	Gene names	SEC13L1, SEC13R
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

SEC13_MOUSE
θ value	0.0431538 (rank : 263)	NC score	0.500899 (rank : 207)
Query Neighborhood Hits	470	Target Neighborhood Hits	195	Shared Neighborhood Hits	163
SwissProt Accessions	Q9D1M0, Q99M12, Q9D712	Gene names	Sec13l1
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

WDR24_HUMAN
θ value	0.0431538 (rank : 264)	NC score	0.432745 (rank : 223)
Query Neighborhood Hits	470	Target Neighborhood Hits	247	Shared Neighborhood Hits	180
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WDR24_MOUSE
θ value	0.0431538 (rank : 265)	NC score	0.556213 (rank : 182)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	202
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

RN166_MOUSE
θ value	0.0563607 (rank : 266)	NC score	0.251872 (rank : 298)
Query Neighborhood Hits	470	Target Neighborhood Hits	248	Shared Neighborhood Hits	149
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI43_HUMAN
θ value	0.0563607 (rank : 267)	NC score	0.203220 (rank : 348)
Query Neighborhood Hits	470	Target Neighborhood Hits	341	Shared Neighborhood Hits	160
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI63_MOUSE
θ value	0.0563607 (rank : 268)	NC score	0.175113 (rank : 399)
Query Neighborhood Hits	470	Target Neighborhood Hits	240	Shared Neighborhood Hits	118
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

WDR43_HUMAN
θ value	0.0563607 (rank : 269)	NC score	0.593524 (rank : 159)
Query Neighborhood Hits	470	Target Neighborhood Hits	269	Shared Neighborhood Hits	170
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

GNB1L_MOUSE
θ value	0.0736092 (rank : 270)	NC score	0.640625 (rank : 137)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	200
SwissProt Accessions	Q9EQ15, Q8R1F3, Q9CWP2, Q9D3Y1	Gene names	Gnb1l, Estm55, Wdr14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF).

GRWD1_HUMAN
θ value	0.0736092 (rank : 271)	NC score	0.605030 (rank : 154)
Query Neighborhood Hits	470	Target Neighborhood Hits	297	Shared Neighborhood Hits	231
SwissProt Accessions	Q9BQ67	Gene names	GRWD1, GRWD, WDR28
Domain Architecture
Description	Glutamate-rich WD repeat-containing protein 1.

GRWD1_MOUSE
θ value	0.0736092 (rank : 272)	NC score	0.602375 (rank : 155)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	229
SwissProt Accessions	Q810D6, Q922H3	Gene names	Grwd1, A301
Domain Architecture	No domain graphic available
Description	Glutamate-rich WD repeat-containing protein 1 (Protein A301).

RN166_HUMAN
θ value	0.0736092 (rank : 273)	NC score	0.249809 (rank : 300)
Query Neighborhood Hits	470	Target Neighborhood Hits	240	Shared Neighborhood Hits	146
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI15_HUMAN
θ value	0.0736092 (rank : 274)	NC score	0.181251 (rank : 394)
Query Neighborhood Hits	470	Target Neighborhood Hits	395	Shared Neighborhood Hits	151
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

WDR81_HUMAN
θ value	0.0736092 (rank : 275)	NC score	0.407275 (rank : 228)
Query Neighborhood Hits	470	Target Neighborhood Hits	205	Shared Neighborhood Hits	164
SwissProt Accessions	Q562E7, Q24JP6, Q8N277, Q8N3F3	Gene names	WDR81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

IF32_HUMAN
θ value	0.0961366 (rank : 276)	NC score	0.649079 (rank : 136)
Query Neighborhood Hits	470	Target Neighborhood Hits	239	Shared Neighborhood Hits	212
SwissProt Accessions	Q13347	Gene names	EIF3S2, TRIP1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

IF32_MOUSE
θ value	0.0961366 (rank : 277)	NC score	0.649997 (rank : 135)
Query Neighborhood Hits	470	Target Neighborhood Hits	239	Shared Neighborhood Hits	212
SwissProt Accessions	Q9QZD9	Gene names	Eif3s2, Trip1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

TRI65_MOUSE
θ value	0.0961366 (rank : 278)	NC score	0.213883 (rank : 332)
Query Neighborhood Hits	470	Target Neighborhood Hits	340	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI73_HUMAN
θ value	0.0961366 (rank : 279)	NC score	0.221314 (rank : 318)
Query Neighborhood Hits	470	Target Neighborhood Hits	258	Shared Neighborhood Hits	154
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRIM2_HUMAN
θ value	0.0961366 (rank : 280)	NC score	0.170167 (rank : 406)
Query Neighborhood Hits	470	Target Neighborhood Hits	330	Shared Neighborhood Hits	152
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

WDR65_HUMAN
θ value	0.0961366 (rank : 281)	NC score	0.591097 (rank : 161)
Query Neighborhood Hits	470	Target Neighborhood Hits	238	Shared Neighborhood Hits	200
SwissProt Accessions	Q96MR6, Q5TAI0	Gene names	WDR65
Domain Architecture	No domain graphic available
Description	WD repeat protein 65.

WDR6_HUMAN
θ value	0.0961366 (rank : 282)	NC score	0.499780 (rank : 208)
Query Neighborhood Hits	470	Target Neighborhood Hits	193	Shared Neighborhood Hits	165
SwissProt Accessions	Q9NNW5, Q9UF63	Gene names	WDR6
Domain Architecture
Description	WD repeat protein 6.

WDR74_MOUSE
θ value	0.0961366 (rank : 283)	NC score	0.209734 (rank : 339)
Query Neighborhood Hits	470	Target Neighborhood Hits	70	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VCG3	Gene names	Wdr74
Domain Architecture	No domain graphic available
Description	WD repeat protein 74.

AHI1_MOUSE
θ value	0.125558 (rank : 284)	NC score	0.484118 (rank : 213)
Query Neighborhood Hits	470	Target Neighborhood Hits	496	Shared Neighborhood Hits	216
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

BFAR_HUMAN
θ value	0.125558 (rank : 285)	NC score	0.200207 (rank : 354)
Query Neighborhood Hits	470	Target Neighborhood Hits	222	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

CORO7_MOUSE
θ value	0.125558 (rank : 286)	NC score	0.497396 (rank : 211)
Query Neighborhood Hits	470	Target Neighborhood Hits	312	Shared Neighborhood Hits	237
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

HIRA_HUMAN
θ value	0.125558 (rank : 287)	NC score	0.556773 (rank : 181)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	203
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

HIRA_MOUSE
θ value	0.125558 (rank : 288)	NC score	0.560105 (rank : 173)
Query Neighborhood Hits	470	Target Neighborhood Hits	274	Shared Neighborhood Hits	204
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

TRI18_HUMAN
θ value	0.125558 (rank : 289)	NC score	0.162994 (rank : 420)
Query Neighborhood Hits	470	Target Neighborhood Hits	307	Shared Neighborhood Hits	138
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	0.125558 (rank : 290)	NC score	0.164785 (rank : 417)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	138
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI30_MOUSE
θ value	0.125558 (rank : 291)	NC score	0.200889 (rank : 351)
Query Neighborhood Hits	470	Target Neighborhood Hits	434	Shared Neighborhood Hits	166
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI63_HUMAN
θ value	0.125558 (rank : 292)	NC score	0.171119 (rank : 402)
Query Neighborhood Hits	470	Target Neighborhood Hits	298	Shared Neighborhood Hits	124
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM2_MOUSE
θ value	0.125558 (rank : 293)	NC score	0.170163 (rank : 407)
Query Neighborhood Hits	470	Target Neighborhood Hits	331	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM9_HUMAN
θ value	0.125558 (rank : 294)	NC score	0.156160 (rank : 427)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	123
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	0.125558 (rank : 295)	NC score	0.157986 (rank : 426)
Query Neighborhood Hits	470	Target Neighborhood Hits	274	Shared Neighborhood Hits	122
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

WDR79_MOUSE
θ value	0.125558 (rank : 296)	NC score	0.545688 (rank : 189)
Query Neighborhood Hits	470	Target Neighborhood Hits	216	Shared Neighborhood Hits	180
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

CAF1B_HUMAN
θ value	0.163984 (rank : 297)	NC score	0.628724 (rank : 144)
Query Neighborhood Hits	470	Target Neighborhood Hits	345	Shared Neighborhood Hits	223
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

DC1I1_HUMAN
θ value	0.163984 (rank : 298)	NC score	0.192406 (rank : 373)
Query Neighborhood Hits	470	Target Neighborhood Hits	183	Shared Neighborhood Hits	106
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DC1I1_MOUSE
θ value	0.163984 (rank : 299)	NC score	0.189567 (rank : 380)
Query Neighborhood Hits	470	Target Neighborhood Hits	206	Shared Neighborhood Hits	109
SwissProt Accessions	O88485, O88486	Gene names	Dync1i1, Dnci1, Dncic1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

PWP1_HUMAN
θ value	0.163984 (rank : 300)	NC score	0.593674 (rank : 157)
Query Neighborhood Hits	470	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

PWP1_MOUSE
θ value	0.163984 (rank : 301)	NC score	0.613652 (rank : 147)
Query Neighborhood Hits	470	Target Neighborhood Hits	278	Shared Neighborhood Hits	216
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

THOC6_HUMAN
θ value	0.163984 (rank : 302)	NC score	0.557768 (rank : 175)
Query Neighborhood Hits	470	Target Neighborhood Hits	223	Shared Neighborhood Hits	204
SwissProt Accessions	Q86W42, Q8NBR1, Q9BTV9	Gene names	THOC6, WDR58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

TRI10_HUMAN
θ value	0.163984 (rank : 303)	NC score	0.199807 (rank : 355)
Query Neighborhood Hits	470	Target Neighborhood Hits	315	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI10_MOUSE
θ value	0.163984 (rank : 304)	NC score	0.196420 (rank : 364)
Query Neighborhood Hits	470	Target Neighborhood Hits	285	Shared Neighborhood Hits	155
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI60_MOUSE
θ value	0.163984 (rank : 305)	NC score	0.191021 (rank : 377)
Query Neighborhood Hits	470	Target Neighborhood Hits	240	Shared Neighborhood Hits	145
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI68_HUMAN
θ value	0.163984 (rank : 306)	NC score	0.190062 (rank : 378)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	149
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI74_HUMAN
θ value	0.163984 (rank : 307)	NC score	0.215828 (rank : 323)
Query Neighborhood Hits	470	Target Neighborhood Hits	249	Shared Neighborhood Hits	150
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM1_HUMAN
θ value	0.163984 (rank : 308)	NC score	0.161614 (rank : 421)
Query Neighborhood Hits	470	Target Neighborhood Hits	345	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.163984 (rank : 309)	NC score	0.160279 (rank : 423)
Query Neighborhood Hits	470	Target Neighborhood Hits	361	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

BRE1B_HUMAN
θ value	0.21417 (rank : 310)	NC score	0.062836 (rank : 563)
Query Neighborhood Hits	470	Target Neighborhood Hits	1040	Shared Neighborhood Hits	149
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	0.21417 (rank : 311)	NC score	0.064685 (rank : 560)
Query Neighborhood Hits	470	Target Neighborhood Hits	970	Shared Neighborhood Hits	147
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

COR1A_HUMAN
θ value	0.21417 (rank : 312)	NC score	0.380054 (rank : 242)
Query Neighborhood Hits	470	Target Neighborhood Hits	240	Shared Neighborhood Hits	188
SwissProt Accessions	P31146	Gene names	CORO1A, CORO1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

DMXL2_HUMAN
θ value	0.21417 (rank : 313)	NC score	0.389046 (rank : 237)
Query Neighborhood Hits	470	Target Neighborhood Hits	374	Shared Neighborhood Hits	203
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

TRI12_MOUSE
θ value	0.21417 (rank : 314)	NC score	0.217929 (rank : 319)
Query Neighborhood Hits	470	Target Neighborhood Hits	387	Shared Neighborhood Hits	165
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI31_HUMAN
θ value	0.21417 (rank : 315)	NC score	0.226319 (rank : 315)
Query Neighborhood Hits	470	Target Neighborhood Hits	299	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

RC3H1_HUMAN
θ value	0.279714 (rank : 316)	NC score	0.096048 (rank : 502)
Query Neighborhood Hits	470	Target Neighborhood Hits	433	Shared Neighborhood Hits	105
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	0.279714 (rank : 317)	NC score	0.101974 (rank : 493)
Query Neighborhood Hits	470	Target Neighborhood Hits	244	Shared Neighborhood Hits	104
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

THOC3_HUMAN
θ value	0.279714 (rank : 318)	NC score	0.669126 (rank : 120)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	230
SwissProt Accessions	Q96J01	Gene names	THOC3
Domain Architecture
Description	THO complex subunit 3 (Tho3) (TEX1 homolog).

THOC3_MOUSE
θ value	0.279714 (rank : 319)	NC score	0.670582 (rank : 119)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	232
SwissProt Accessions	Q8VE80, Q9CWI8	Gene names	Thoc3
Domain Architecture
Description	THO complex subunit 3 (Tho3).

BRE1A_HUMAN
θ value	0.365318 (rank : 320)	NC score	0.057248 (rank : 574)
Query Neighborhood Hits	470	Target Neighborhood Hits	1071	Shared Neighborhood Hits	141
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	0.365318 (rank : 321)	NC score	0.057802 (rank : 573)
Query Neighborhood Hits	470	Target Neighborhood Hits	1025	Shared Neighborhood Hits	141
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

DC1I2_HUMAN
θ value	0.365318 (rank : 322)	NC score	0.227646 (rank : 314)
Query Neighborhood Hits	470	Target Neighborhood Hits	201	Shared Neighborhood Hits	127
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

DC1I2_MOUSE
θ value	0.365318 (rank : 323)	NC score	0.231317 (rank : 310)
Query Neighborhood Hits	470	Target Neighborhood Hits	209	Shared Neighborhood Hits	129
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

RBBP5_HUMAN
θ value	0.365318 (rank : 324)	NC score	0.524125 (rank : 200)
Query Neighborhood Hits	470	Target Neighborhood Hits	372	Shared Neighborhood Hits	181
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

RN168_HUMAN
θ value	0.365318 (rank : 325)	NC score	0.184892 (rank : 389)
Query Neighborhood Hits	470	Target Neighborhood Hits	370	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRAF2_HUMAN
θ value	0.365318 (rank : 326)	NC score	0.192803 (rank : 371)
Query Neighborhood Hits	470	Target Neighborhood Hits	402	Shared Neighborhood Hits	112
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

WDR1_HUMAN
θ value	0.365318 (rank : 327)	NC score	0.660779 (rank : 125)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	230
SwissProt Accessions	O75083, O75313, Q8N6E5, Q9UG05, Q9UG78, Q9UQE0	Gene names	WDR1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1).

WDR7_MOUSE
θ value	0.365318 (rank : 328)	NC score	0.411803 (rank : 227)
Query Neighborhood Hits	470	Target Neighborhood Hits	226	Shared Neighborhood Hits	187
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

ZAN_MOUSE
θ value	0.365318 (rank : 329)	NC score	0.000328 (rank : 635)
Query Neighborhood Hits	470	Target Neighborhood Hits	808	Shared Neighborhood Hits	10
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LYST_HUMAN
θ value	0.47712 (rank : 330)	NC score	0.346911 (rank : 258)
Query Neighborhood Hits	470	Target Neighborhood Hits	324	Shared Neighborhood Hits	168
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

MNAB_HUMAN
θ value	0.47712 (rank : 331)	NC score	0.083607 (rank : 527)
Query Neighborhood Hits	470	Target Neighborhood Hits	196	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	0.47712 (rank : 332)	NC score	0.082910 (rank : 528)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	86
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MYLIP_HUMAN
θ value	0.47712 (rank : 333)	NC score	0.033064 (rank : 597)
Query Neighborhood Hits	470	Target Neighborhood Hits	162	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RN185_HUMAN
θ value	0.47712 (rank : 334)	NC score	0.170307 (rank : 405)
Query Neighborhood Hits	470	Target Neighborhood Hits	213	Shared Neighborhood Hits	134
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	0.47712 (rank : 335)	NC score	0.169937 (rank : 408)
Query Neighborhood Hits	470	Target Neighborhood Hits	211	Shared Neighborhood Hits	134
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

THOC6_MOUSE
θ value	0.47712 (rank : 336)	NC score	0.518654 (rank : 202)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	182
SwissProt Accessions	Q5U4D9	Gene names	Thoc6, Wdr58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

TRI34_HUMAN
θ value	0.47712 (rank : 337)	NC score	0.184968 (rank : 388)
Query Neighborhood Hits	470	Target Neighborhood Hits	416	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI38_HUMAN
θ value	0.47712 (rank : 338)	NC score	0.182994 (rank : 393)
Query Neighborhood Hits	470	Target Neighborhood Hits	373	Shared Neighborhood Hits	155
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

WDR41_HUMAN
θ value	0.47712 (rank : 339)	NC score	0.479704 (rank : 215)
Query Neighborhood Hits	470	Target Neighborhood Hits	208	Shared Neighborhood Hits	184
SwissProt Accessions	Q9HAD4, Q7Z792, Q8IWG3, Q8IXA9, Q8NDA7, Q9NV62	Gene names	WDR41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WDR41_MOUSE
θ value	0.47712 (rank : 340)	NC score	0.506158 (rank : 205)
Query Neighborhood Hits	470	Target Neighborhood Hits	209	Shared Neighborhood Hits	179
SwissProt Accessions	Q3UDP0, Q8C4F1, Q8C8K5	Gene names	Wdr41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

BOP1_HUMAN
θ value	0.62314 (rank : 341)	NC score	0.483501 (rank : 214)
Query Neighborhood Hits	470	Target Neighborhood Hits	257	Shared Neighborhood Hits	203
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

COR1A_MOUSE
θ value	0.62314 (rank : 342)	NC score	0.387716 (rank : 238)
Query Neighborhood Hits	470	Target Neighborhood Hits	243	Shared Neighborhood Hits	193
SwissProt Accessions	O89053, Q7TMU0, Q9R1Y8, Q9R288	Gene names	Coro1a, Coro1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

CP250_MOUSE
θ value	0.62314 (rank : 343)	NC score	0.026209 (rank : 603)
Query Neighborhood Hits	470	Target Neighborhood Hits	1583	Shared Neighborhood Hits	91
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

FBXW8_MOUSE
θ value	0.62314 (rank : 344)	NC score	0.292137 (rank : 282)
Query Neighborhood Hits	470	Target Neighborhood Hits	162	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

NBEAL_HUMAN
θ value	0.62314 (rank : 345)	NC score	0.314616 (rank : 273)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	157
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

NEDD1_MOUSE
θ value	0.62314 (rank : 346)	NC score	0.557027 (rank : 179)
Query Neighborhood Hits	470	Target Neighborhood Hits	281	Shared Neighborhood Hits	208
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

PEX12_HUMAN
θ value	0.62314 (rank : 347)	NC score	0.058080 (rank : 569)
Query Neighborhood Hits	470	Target Neighborhood Hits	32	Shared Neighborhood Hits	21
SwissProt Accessions	O00623	Gene names	PEX12, PAF3
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3).

PEX12_MOUSE
θ value	0.62314 (rank : 348)	NC score	0.060191 (rank : 565)
Query Neighborhood Hits	470	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VC48	Gene names	Pex12
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12).

SMRA3_HUMAN
θ value	0.62314 (rank : 349)	NC score	0.110520 (rank : 474)
Query Neighborhood Hits	470	Target Neighborhood Hits	265	Shared Neighborhood Hits	138
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TBL2_MOUSE
θ value	0.62314 (rank : 350)	NC score	0.553555 (rank : 183)
Query Neighborhood Hits	470	Target Neighborhood Hits	221	Shared Neighborhood Hits	189
SwissProt Accessions	Q9R099	Gene names	Tbl2
Domain Architecture
Description	Transducin beta-like 2 protein.

TRI40_HUMAN
θ value	0.62314 (rank : 351)	NC score	0.216994 (rank : 320)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	159
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

WDR67_MOUSE
θ value	0.62314 (rank : 352)	NC score	0.301023 (rank : 278)
Query Neighborhood Hits	470	Target Neighborhood Hits	476	Shared Neighborhood Hits	141
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

CEP63_HUMAN
θ value	0.813845 (rank : 353)	NC score	0.023017 (rank : 609)
Query Neighborhood Hits	470	Target Neighborhood Hits	1005	Shared Neighborhood Hits	64
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

MEP50_HUMAN
θ value	0.813845 (rank : 354)	NC score	0.588440 (rank : 162)
Query Neighborhood Hits	470	Target Neighborhood Hits	268	Shared Neighborhood Hits	212
SwissProt Accessions	Q9BQA1, Q96GK4, Q9BWY3	Gene names	WDR77, MEP50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

MYLIP_MOUSE
θ value	0.813845 (rank : 355)	NC score	0.025974 (rank : 605)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

SMC3_HUMAN
θ value	0.813845 (rank : 356)	NC score	0.030273 (rank : 598)
Query Neighborhood Hits	470	Target Neighborhood Hits	1186	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	0.813845 (rank : 357)	NC score	0.028414 (rank : 600)
Query Neighborhood Hits	470	Target Neighborhood Hits	1187	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMRA3_MOUSE
θ value	0.813845 (rank : 358)	NC score	0.107873 (rank : 479)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	144
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRAF1_MOUSE
θ value	0.813845 (rank : 359)	NC score	0.150452 (rank : 434)
Query Neighborhood Hits	470	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

TRI32_MOUSE
θ value	0.813845 (rank : 360)	NC score	0.169686 (rank : 409)
Query Neighborhood Hits	470	Target Neighborhood Hits	271	Shared Neighborhood Hits	134
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRIM5_HUMAN
θ value	0.813845 (rank : 361)	NC score	0.193507 (rank : 369)
Query Neighborhood Hits	470	Target Neighborhood Hits	424	Shared Neighborhood Hits	171
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

WDR22_HUMAN
θ value	0.813845 (rank : 362)	NC score	0.505397 (rank : 206)
Query Neighborhood Hits	470	Target Neighborhood Hits	328	Shared Neighborhood Hits	198
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

WDR22_MOUSE
θ value	0.813845 (rank : 363)	NC score	0.508022 (rank : 204)
Query Neighborhood Hits	470	Target Neighborhood Hits	302	Shared Neighborhood Hits	197
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

WDR67_HUMAN
θ value	0.813845 (rank : 364)	NC score	0.247798 (rank : 302)
Query Neighborhood Hits	470	Target Neighborhood Hits	782	Shared Neighborhood Hits	157
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

TRI22_HUMAN
θ value	1.06291 (rank : 365)	NC score	0.196896 (rank : 362)
Query Neighborhood Hits	470	Target Neighborhood Hits	396	Shared Neighborhood Hits	164
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI32_HUMAN
θ value	1.06291 (rank : 366)	NC score	0.170862 (rank : 403)
Query Neighborhood Hits	470	Target Neighborhood Hits	264	Shared Neighborhood Hits	132
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI46_HUMAN
θ value	1.06291 (rank : 367)	NC score	0.142143 (rank : 442)
Query Neighborhood Hits	470	Target Neighborhood Hits	291	Shared Neighborhood Hits	127
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	1.06291 (rank : 368)	NC score	0.142496 (rank : 440)
Query Neighborhood Hits	470	Target Neighborhood Hits	287	Shared Neighborhood Hits	125
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI54_HUMAN
θ value	1.06291 (rank : 369)	NC score	0.169596 (rank : 410)
Query Neighborhood Hits	470	Target Neighborhood Hits	209	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	1.06291 (rank : 370)	NC score	0.169223 (rank : 412)
Query Neighborhood Hits	470	Target Neighborhood Hits	197	Shared Neighborhood Hits	116
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM6_HUMAN
θ value	1.06291 (rank : 371)	NC score	0.186408 (rank : 384)
Query Neighborhood Hits	470	Target Neighborhood Hits	412	Shared Neighborhood Hits	154
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

WDR79_HUMAN
θ value	1.06291 (rank : 372)	NC score	0.499033 (rank : 209)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	177
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

BIRC8_HUMAN
θ value	1.38821 (rank : 373)	NC score	0.048241 (rank : 586)
Query Neighborhood Hits	470	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

FATH_HUMAN
θ value	1.38821 (rank : 374)	NC score	-0.005067 (rank : 638)
Query Neighborhood Hits	470	Target Neighborhood Hits	570	Shared Neighborhood Hits	6
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

GOGA3_MOUSE
θ value	1.38821 (rank : 375)	NC score	0.021713 (rank : 611)
Query Neighborhood Hits	470	Target Neighborhood Hits	1437	Shared Neighborhood Hits	85
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

HOOK1_MOUSE
θ value	1.38821 (rank : 376)	NC score	0.021567 (rank : 613)
Query Neighborhood Hits	470	Target Neighborhood Hits	910	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

NBEA_HUMAN
θ value	1.38821 (rank : 377)	NC score	0.214086 (rank : 329)
Query Neighborhood Hits	470	Target Neighborhood Hits	186	Shared Neighborhood Hits	107
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
θ value	1.38821 (rank : 378)	NC score	0.213313 (rank : 335)
Query Neighborhood Hits	470	Target Neighborhood Hits	225	Shared Neighborhood Hits	110
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

PJA1_HUMAN
θ value	1.38821 (rank : 379)	NC score	0.052197 (rank : 581)
Query Neighborhood Hits	470	Target Neighborhood Hits	159	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	1.38821 (rank : 380)	NC score	0.049056 (rank : 584)
Query Neighborhood Hits	470	Target Neighborhood Hits	145	Shared Neighborhood Hits	45
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

TRI47_HUMAN
θ value	1.38821 (rank : 381)	NC score	0.185614 (rank : 387)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	146
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
θ value	1.38821 (rank : 382)	NC score	0.187711 (rank : 383)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	147
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI55_HUMAN
θ value	1.38821 (rank : 383)	NC score	0.170545 (rank : 404)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRIM6_MOUSE
θ value	1.38821 (rank : 384)	NC score	0.183153 (rank : 392)
Query Neighborhood Hits	470	Target Neighborhood Hits	451	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

WD21C_HUMAN
θ value	1.38821 (rank : 385)	NC score	0.425276 (rank : 224)
Query Neighborhood Hits	470	Target Neighborhood Hits	157	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

WDR1_MOUSE
θ value	1.38821 (rank : 386)	NC score	0.651553 (rank : 132)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	230
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

WDR85_HUMAN
θ value	1.38821 (rank : 387)	NC score	0.273604 (rank : 288)
Query Neighborhood Hits	470	Target Neighborhood Hits	134	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BTV6, Q96AB7	Gene names	WDR85, C9orf112
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

BIRC7_HUMAN
θ value	1.81305 (rank : 388)	NC score	0.103772 (rank : 492)
Query Neighborhood Hits	470	Target Neighborhood Hits	185	Shared Neighborhood Hits	123
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CP250_HUMAN
θ value	1.81305 (rank : 389)	NC score	0.026201 (rank : 604)
Query Neighborhood Hits	470	Target Neighborhood Hits	1805	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

KTN1_MOUSE
θ value	1.81305 (rank : 390)	NC score	0.019128 (rank : 616)
Query Neighborhood Hits	470	Target Neighborhood Hits	1324	Shared Neighborhood Hits	77
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MKRN1_HUMAN
θ value	1.81305 (rank : 391)	NC score	0.045641 (rank : 588)
Query Neighborhood Hits	470	Target Neighborhood Hits	141	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

RN168_MOUSE
θ value	1.81305 (rank : 392)	NC score	0.169577 (rank : 411)
Query Neighborhood Hits	470	Target Neighborhood Hits	440	Shared Neighborhood Hits	162
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF14_MOUSE
θ value	1.81305 (rank : 393)	NC score	0.028106 (rank : 601)
Query Neighborhood Hits	470	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

RO52_MOUSE
θ value	1.81305 (rank : 394)	NC score	0.185770 (rank : 386)
Query Neighborhood Hits	470	Target Neighborhood Hits	360	Shared Neighborhood Hits	166
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

FBX30_HUMAN
θ value	2.36792 (rank : 395)	NC score	0.028582 (rank : 599)
Query Neighborhood Hits	470	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TB52, Q9BXZ7	Gene names	FBXO30, FBX30
Domain Architecture
Description	F-box only protein 30.

LRBA_HUMAN
θ value	2.36792 (rank : 396)	NC score	0.210217 (rank : 337)
Query Neighborhood Hits	470	Target Neighborhood Hits	196	Shared Neighborhood Hits	98
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

MGRN1_HUMAN
θ value	2.36792 (rank : 397)	NC score	0.058035 (rank : 570)
Query Neighborhood Hits	470	Target Neighborhood Hits	192	Shared Neighborhood Hits	79
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MKRN3_MOUSE
θ value	2.36792 (rank : 398)	NC score	0.038995 (rank : 596)
Query Neighborhood Hits	470	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

PEX10_HUMAN
θ value	2.36792 (rank : 399)	NC score	0.189823 (rank : 379)
Query Neighborhood Hits	470	Target Neighborhood Hits	255	Shared Neighborhood Hits	145
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

POF1B_HUMAN
θ value	2.36792 (rank : 400)	NC score	0.018992 (rank : 617)
Query Neighborhood Hits	470	Target Neighborhood Hits	494	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

RNF34_HUMAN
θ value	2.36792 (rank : 401)	NC score	0.064402 (rank : 562)
Query Neighborhood Hits	470	Target Neighborhood Hits	153	Shared Neighborhood Hits	76
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	2.36792 (rank : 402)	NC score	0.064611 (rank : 561)
Query Neighborhood Hits	470	Target Neighborhood Hits	160	Shared Neighborhood Hits	76
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

UHRF2_HUMAN
θ value	2.36792 (rank : 403)	NC score	0.115643 (rank : 469)
Query Neighborhood Hits	470	Target Neighborhood Hits	269	Shared Neighborhood Hits	138
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	2.36792 (rank : 404)	NC score	0.115161 (rank : 470)
Query Neighborhood Hits	470	Target Neighborhood Hits	275	Shared Neighborhood Hits	138
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

RNF5_HUMAN
θ value	3.0926 (rank : 405)	NC score	0.152092 (rank : 432)
Query Neighborhood Hits	470	Target Neighborhood Hits	206	Shared Neighborhood Hits	130
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	3.0926 (rank : 406)	NC score	0.150144 (rank : 435)
Query Neighborhood Hits	470	Target Neighborhood Hits	206	Shared Neighborhood Hits	128
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI45_HUMAN
θ value	3.0926 (rank : 407)	NC score	0.088522 (rank : 520)
Query Neighborhood Hits	470	Target Neighborhood Hits	155	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

COR1C_HUMAN
θ value	4.03905 (rank : 408)	NC score	0.376285 (rank : 244)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	186
SwissProt Accessions	Q9ULV4, Q9NSK5	Gene names	CORO1C, CRNN4
Domain Architecture
Description	Coronin-1C (Coronin-3) (hCRNN4).

COR1C_MOUSE
θ value	4.03905 (rank : 409)	NC score	0.374298 (rank : 245)
Query Neighborhood Hits	470	Target Neighborhood Hits	251	Shared Neighborhood Hits	187
SwissProt Accessions	Q9WUM4, Q8VCQ5	Gene names	Coro1c
Domain Architecture
Description	Coronin-1C (Coronin-3).

CP135_MOUSE
θ value	4.03905 (rank : 410)	NC score	0.023244 (rank : 608)
Query Neighborhood Hits	470	Target Neighborhood Hits	1278	Shared Neighborhood Hits	74
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CYLN2_MOUSE
θ value	4.03905 (rank : 411)	NC score	0.018362 (rank : 618)
Query Neighborhood Hits	470	Target Neighborhood Hits	1002	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

M3KL4_HUMAN
θ value	4.03905 (rank : 412)	NC score	-0.014207 (rank : 639)
Query Neighborhood Hits	470	Target Neighborhood Hits	1087	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MKRN1_MOUSE
θ value	4.03905 (rank : 413)	NC score	0.040626 (rank : 592)
Query Neighborhood Hits	470	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MMRN1_HUMAN
θ value	4.03905 (rank : 414)	NC score	0.009730 (rank : 631)
Query Neighborhood Hits	470	Target Neighborhood Hits	636	Shared Neighborhood Hits	32
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

PHF14_HUMAN
θ value	4.03905 (rank : 415)	NC score	0.009559 (rank : 632)
Query Neighborhood Hits	470	Target Neighborhood Hits	447	Shared Neighborhood Hits	27
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	4.03905 (rank : 416)	NC score	0.010065 (rank : 630)
Query Neighborhood Hits	470	Target Neighborhood Hits	342	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

RFIP3_HUMAN
θ value	4.03905 (rank : 417)	NC score	0.019141 (rank : 615)
Query Neighborhood Hits	470	Target Neighborhood Hits	1055	Shared Neighborhood Hits	57
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

TRI36_HUMAN
θ value	4.03905 (rank : 418)	NC score	0.127266 (rank : 455)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

WDR49_HUMAN
θ value	4.03905 (rank : 419)	NC score	0.585364 (rank : 163)
Query Neighborhood Hits	470	Target Neighborhood Hits	214	Shared Neighborhood Hits	181
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

WDR7_HUMAN
θ value	4.03905 (rank : 420)	NC score	0.399809 (rank : 229)
Query Neighborhood Hits	470	Target Neighborhood Hits	244	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

ANR26_MOUSE
θ value	5.27518 (rank : 421)	NC score	0.012936 (rank : 624)
Query Neighborhood Hits	470	Target Neighborhood Hits	1554	Shared Neighborhood Hits	70
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CBLB_HUMAN
θ value	5.27518 (rank : 422)	NC score	0.066367 (rank : 556)
Query Neighborhood Hits	470	Target Neighborhood Hits	261	Shared Neighborhood Hits	113
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	5.27518 (rank : 423)	NC score	0.067559 (rank : 553)
Query Neighborhood Hits	470	Target Neighborhood Hits	277	Shared Neighborhood Hits	116
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBL_HUMAN
θ value	5.27518 (rank : 424)	NC score	0.070301 (rank : 546)
Query Neighborhood Hits	470	Target Neighborhood Hits	353	Shared Neighborhood Hits	123
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	5.27518 (rank : 425)	NC score	0.068485 (rank : 551)
Query Neighborhood Hits	470	Target Neighborhood Hits	426	Shared Neighborhood Hits	126
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CORO7_HUMAN
θ value	5.27518 (rank : 426)	NC score	0.469275 (rank : 216)
Query Neighborhood Hits	470	Target Neighborhood Hits	315	Shared Neighborhood Hits	231
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

DIP2A_MOUSE
θ value	5.27518 (rank : 427)	NC score	0.011714 (rank : 628)
Query Neighborhood Hits	470	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

EEA1_MOUSE
θ value	5.27518 (rank : 428)	NC score	0.025273 (rank : 606)
Query Neighborhood Hits	470	Target Neighborhood Hits	1637	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FBX30_MOUSE
θ value	5.27518 (rank : 429)	NC score	0.021939 (rank : 610)
Query Neighborhood Hits	470	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BJL1, Q8CI21, Q9D9X5	Gene names	Fbxo30
Domain Architecture
Description	F-box only protein 30.

GCC2_MOUSE
θ value	5.27518 (rank : 430)	NC score	0.023720 (rank : 607)
Query Neighborhood Hits	470	Target Neighborhood Hits	1619	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

HOOK1_HUMAN
θ value	5.27518 (rank : 431)	NC score	0.017374 (rank : 619)
Query Neighborhood Hits	470	Target Neighborhood Hits	942	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

LRP1B_HUMAN
θ value	5.27518 (rank : 432)	NC score	-0.003986 (rank : 637)
Query Neighborhood Hits	470	Target Neighborhood Hits	602	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NEUL1_HUMAN
θ value	5.27518 (rank : 433)	NC score	0.048931 (rank : 585)
Query Neighborhood Hits	470	Target Neighborhood Hits	114	Shared Neighborhood Hits	60
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	5.27518 (rank : 434)	NC score	0.048124 (rank : 587)
Query Neighborhood Hits	470	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

PIBF1_HUMAN
θ value	5.27518 (rank : 435)	NC score	0.021641 (rank : 612)
Query Neighborhood Hits	470	Target Neighborhood Hits	1041	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

TRI36_MOUSE
θ value	5.27518 (rank : 436)	NC score	0.125208 (rank : 460)
Query Neighborhood Hits	470	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI42_HUMAN
θ value	5.27518 (rank : 437)	NC score	0.089316 (rank : 518)
Query Neighborhood Hits	470	Target Neighborhood Hits	283	Shared Neighborhood Hits	92
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZN330_HUMAN
θ value	5.27518 (rank : 438)	NC score	0.012763 (rank : 625)
Query Neighborhood Hits	470	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ZN330_MOUSE
θ value	5.27518 (rank : 439)	NC score	0.012659 (rank : 626)
Query Neighborhood Hits	470	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q922H9, Q8C389, Q8K2M4	Gene names	Znf330, Noa36, Zfp330
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

CBLC_HUMAN
θ value	6.88961 (rank : 440)	NC score	0.069632 (rank : 548)
Query Neighborhood Hits	470	Target Neighborhood Hits	173	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	6.88961 (rank : 441)	NC score	0.068547 (rank : 550)
Query Neighborhood Hits	470	Target Neighborhood Hits	186	Shared Neighborhood Hits	104
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CM007_MOUSE
θ value	6.88961 (rank : 442)	NC score	0.096638 (rank : 500)
Query Neighborhood Hits	470	Target Neighborhood Hits	416	Shared Neighborhood Hits	118
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DIAP1_MOUSE
θ value	6.88961 (rank : 443)	NC score	0.011313 (rank : 629)
Query Neighborhood Hits	470	Target Neighborhood Hits	839	Shared Neighborhood Hits	46
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DNAI2_HUMAN
θ value	6.88961 (rank : 444)	NC score	0.224407 (rank : 316)
Query Neighborhood Hits	470	Target Neighborhood Hits	156	Shared Neighborhood Hits	110
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

EEA1_HUMAN
θ value	6.88961 (rank : 445)	NC score	0.026421 (rank : 602)
Query Neighborhood Hits	470	Target Neighborhood Hits	1796	Shared Neighborhood Hits	112
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EP15R_HUMAN
θ value	6.88961 (rank : 446)	NC score	0.015915 (rank : 621)
Query Neighborhood Hits	470	Target Neighborhood Hits	1083	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

GOGA4_HUMAN
θ value	6.88961 (rank : 447)	NC score	0.020140 (rank : 614)
Query Neighborhood Hits	470	Target Neighborhood Hits	2034	Shared Neighborhood Hits	106
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MKRN4_HUMAN
θ value	6.88961 (rank : 448)	NC score	0.045130 (rank : 589)
Query Neighborhood Hits	470	Target Neighborhood Hits	147	Shared Neighborhood Hits	69
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

PREB_HUMAN
θ value	6.88961 (rank : 449)	NC score	0.328945 (rank : 264)
Query Neighborhood Hits	470	Target Neighborhood Hits	163	Shared Neighborhood Hits	142
SwissProt Accessions	Q9HCU5, Q9UH94	Gene names	PREB, SEC12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

RNF4_HUMAN
θ value	6.88961 (rank : 450)	NC score	0.148079 (rank : 436)
Query Neighborhood Hits	470	Target Neighborhood Hits	212	Shared Neighborhood Hits	131
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	6.88961 (rank : 451)	NC score	0.147090 (rank : 437)
Query Neighborhood Hits	470	Target Neighborhood Hits	212	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF8_MOUSE
θ value	6.88961 (rank : 452)	NC score	0.151109 (rank : 433)
Query Neighborhood Hits	470	Target Neighborhood Hits	618	Shared Neighborhood Hits	178
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

ZBED4_HUMAN
θ value	6.88961 (rank : 453)	NC score	0.014463 (rank : 622)
Query Neighborhood Hits	470	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O75132, Q9UGG8	Gene names	ZBED4, KIAA0637
Domain Architecture
Description	Zinc finger BED domain-containing protein 4.

BPA1_MOUSE
θ value	8.99809 (rank : 454)	NC score	0.008803 (rank : 633)
Query Neighborhood Hits	470	Target Neighborhood Hits	1477	Shared Neighborhood Hits	64
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DIP2A_HUMAN
θ value	8.99809 (rank : 455)	NC score	0.007650 (rank : 634)
Query Neighborhood Hits	470	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

IF122_HUMAN
θ value	8.99809 (rank : 456)	NC score	0.538725 (rank : 195)
Query Neighborhood Hits	470	Target Neighborhood Hits	244	Shared Neighborhood Hits	209
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

KIF3A_HUMAN
θ value	8.99809 (rank : 457)	NC score	0.039295 (rank : 593)
Query Neighborhood Hits	470	Target Neighborhood Hits	704	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_MOUSE
θ value	8.99809 (rank : 458)	NC score	0.039149 (rank : 594)
Query Neighborhood Hits	470	Target Neighborhood Hits	715	Shared Neighborhood Hits	47
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

LIPA1_HUMAN
θ value	8.99809 (rank : 459)	NC score	0.017093 (rank : 620)
Query Neighborhood Hits	470	Target Neighborhood Hits	1294	Shared Neighborhood Hits	64
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LUZP1_MOUSE
θ value	8.99809 (rank : 460)	NC score	0.013153 (rank : 623)
Query Neighborhood Hits	470	Target Neighborhood Hits	940	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MKRN3_HUMAN
θ value	8.99809 (rank : 461)	NC score	0.039021 (rank : 595)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MMGL_MOUSE
θ value	8.99809 (rank : 462)	NC score	-0.000508 (rank : 636)
Query Neighborhood Hits	470	Target Neighborhood Hits	270	Shared Neighborhood Hits	16
SwissProt Accessions	P49300	Gene names	Mgl1, Mgl
Domain Architecture
Description	Macrophage asialoglycoprotein-binding protein 1 (M-ASGP-BP) (Macrophage galactose/N-acetylgalactosamine-specific lectin) (MMGL).

PCGF4_HUMAN
θ value	8.99809 (rank : 463)	NC score	0.077175 (rank : 537)
Query Neighborhood Hits	470	Target Neighborhood Hits	161	Shared Neighborhood Hits	90
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	8.99809 (rank : 464)	NC score	0.077330 (rank : 536)
Query Neighborhood Hits	470	Target Neighborhood Hits	163	Shared Neighborhood Hits	89
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RFFL_HUMAN
θ value	8.99809 (rank : 465)	NC score	0.042782 (rank : 590)
Query Neighborhood Hits	470	Target Neighborhood Hits	175	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	8.99809 (rank : 466)	NC score	0.042471 (rank : 591)
Query Neighborhood Hits	470	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

TBL2_HUMAN
θ value	8.99809 (rank : 467)	NC score	0.559483 (rank : 174)
Query Neighborhood Hits	470	Target Neighborhood Hits	225	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y4P3, Q9UQE2	Gene names	TBL2, WBSCR13
Domain Architecture
Description	Transducin beta-like 2 protein (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein).

TXLNA_MOUSE
θ value	8.99809 (rank : 468)	NC score	0.011841 (rank : 627)
Query Neighborhood Hits	470	Target Neighborhood Hits	846	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

WDR46_HUMAN
θ value	8.99809 (rank : 469)	NC score	0.265243 (rank : 290)
Query Neighborhood Hits	470	Target Neighborhood Hits	147	Shared Neighborhood Hits	105
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WDR85_MOUSE
θ value	8.99809 (rank : 470)	NC score	0.186005 (rank : 385)
Query Neighborhood Hits	470	Target Neighborhood Hits	108	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CYU6, Q5RJV7, Q8BIT9	Gene names	Wdr85
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

AAAS_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.297919 (rank : 280)
Query Neighborhood Hits	470	Target Neighborhood Hits	154	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NRG9, Q9NWI6, Q9UG19	Gene names	AAAS, ADRACALA
Domain Architecture
Description	Aladin (Adracalin).

AAAS_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.251375 (rank : 299)
Query Neighborhood Hits	470	Target Neighborhood Hits	144	Shared Neighborhood Hits	112
SwissProt Accessions	P58742, Q544M6	Gene names	Aaas
Domain Architecture
Description	Aladin (Adracalin).

AES_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.113483 (rank : 473)
Query Neighborhood Hits	470	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q08117, Q12808, Q96TG9, Q9UDY9	Gene names	AES, GRG
Domain Architecture
Description	Amino-terminal enhancer of split (Amino enhancer of split) (GRG protein) (Protein ESP1) (Gp130-associated protein GAM).

AES_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.113549 (rank : 472)
Query Neighborhood Hits	470	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	P63002, Q06195	Gene names	Aes, Esp1, Grg
Domain Architecture	No domain graphic available
Description	Amino-terminal enhancer of split (Amino enhancer of split) (GRG protein) (Protein ESP1) (Grg-5).

AHI1_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.453180 (rank : 220)
Query Neighborhood Hits	470	Target Neighborhood Hits	537	Shared Neighborhood Hits	212
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AMFR2_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.067000 (rank : 555)
Query Neighborhood Hits	470	Target Neighborhood Hits	219	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.065603 (rank : 558)
Query Neighborhood Hits	470	Target Neighborhood Hits	208	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ARC1A_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.176755 (rank : 396)
Query Neighborhood Hits	470	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q92747, Q7Z5U8, Q86WU5, Q8IXQ0	Gene names	ARPC1A, SOP2L
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein).

ARC1A_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.176716 (rank : 397)
Query Neighborhood Hits	470	Target Neighborhood Hits	120	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0Q6, Q3UL75	Gene names	Arpc1a, Sid329
Domain Architecture	No domain graphic available
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329).

ARC1B_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.232509 (rank : 309)
Query Neighborhood Hits	470	Target Neighborhood Hits	148	Shared Neighborhood Hits	123
SwissProt Accessions	O15143, Q9BU00	Gene names	ARPC1B, ARC41
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

ARC1B_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.214584 (rank : 328)
Query Neighborhood Hits	470	Target Neighborhood Hits	133	Shared Neighborhood Hits	110
SwissProt Accessions	Q9WV32	Gene names	Arpc1b
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

BRWD2_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.175951 (rank : 398)
Query Neighborhood Hits	470	Target Neighborhood Hits	94	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BZH6, Q5VWA1	Gene names	BRWD2, WDR11
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 2 (WD repeat protein 11).

BSPRY_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.104629 (rank : 488)
Query Neighborhood Hits	470	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.109828 (rank : 475)
Query Neighborhood Hits	470	Target Neighborhood Hits	163	Shared Neighborhood Hits	65
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.092778 (rank : 508)
Query Neighborhood Hits	470	Target Neighborhood Hits	322	Shared Neighborhood Hits	54
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.094958 (rank : 504)
Query Neighborhood Hits	470	Target Neighborhood Hits	252	Shared Neighborhood Hits	54
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.089640 (rank : 517)
Query Neighborhood Hits	470	Target Neighborhood Hits	185	Shared Neighborhood Hits	53
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.093444 (rank : 506)
Query Neighborhood Hits	470	Target Neighborhood Hits	191	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.089731 (rank : 516)
Query Neighborhood Hits	470	Target Neighborhood Hits	195	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.092408 (rank : 509)
Query Neighborhood Hits	470	Target Neighborhood Hits	229	Shared Neighborhood Hits	54
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.093320 (rank : 507)
Query Neighborhood Hits	470	Target Neighborhood Hits	233	Shared Neighborhood Hits	54
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.090649 (rank : 513)
Query Neighborhood Hits	470	Target Neighborhood Hits	143	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.086524 (rank : 523)
Query Neighborhood Hits	470	Target Neighborhood Hits	177	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.091123 (rank : 512)
Query Neighborhood Hits	470	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CHFR_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.127061 (rank : 456)
Query Neighborhood Hits	470	Target Neighborhood Hits	255	Shared Neighborhood Hits	131
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.126171 (rank : 457)
Query Neighborhood Hits	470	Target Neighborhood Hits	264	Shared Neighborhood Hits	134
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CM007_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.079411 (rank : 531)
Query Neighborhood Hits	470	Target Neighborhood Hits	422	Shared Neighborhood Hits	119
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

COR2A_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.339702 (rank : 260)
Query Neighborhood Hits	470	Target Neighborhood Hits	214	Shared Neighborhood Hits	165
SwissProt Accessions	Q92828, Q92829, Q9BWS5	Gene names	CORO2A, IR10, WDR2
Domain Architecture
Description	Coronin-2A (WD repeat-containing protein 2) (IR10).

COR2A_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.329895 (rank : 263)
Query Neighborhood Hits	470	Target Neighborhood Hits	204	Shared Neighborhood Hits	154
SwissProt Accessions	Q8C0P5, Q3U6H8, Q8BW42	Gene names	Coro2a
Domain Architecture	No domain graphic available
Description	Coronin-2A.

COR2B_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.392699 (rank : 233)
Query Neighborhood Hits	470	Target Neighborhood Hits	233	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UQ03, O94767, Q8TAN1	Gene names	CORO2B, KIAA0925
Domain Architecture
Description	Coronin-2B (Coronin-like protein C) (ClipinC) (Protein FC96).

COR2B_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.390088 (rank : 235)
Query Neighborhood Hits	470	Target Neighborhood Hits	235	Shared Neighborhood Hits	194
SwissProt Accessions	Q8BH44, Q6P5U9	Gene names	Coro2b
Domain Architecture	No domain graphic available
Description	Coronin-2B.

CORO6_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.391070 (rank : 234)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	186
SwissProt Accessions	Q920M5, Q920M3, Q920M4	Gene names	Coro6
Domain Architecture	No domain graphic available
Description	Coronin-6 (Clipin E).

DDB2_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.337825 (rank : 261)
Query Neighborhood Hits	470	Target Neighborhood Hits	175	Shared Neighborhood Hits	140
SwissProt Accessions	Q92466, Q76E54, Q76E55, Q76E56, Q76E57	Gene names	DDB2
Domain Architecture
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2).

DDB2_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.334946 (rank : 262)
Query Neighborhood Hits	470	Target Neighborhood Hits	175	Shared Neighborhood Hits	145
SwissProt Accessions	Q99J79	Gene names	Ddb2
Domain Architecture	No domain graphic available
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2).

DMWD_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.397272 (rank : 231)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	175
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

DMXL1_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.298617 (rank : 279)
Query Neighborhood Hits	470	Target Neighborhood Hits	259	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

DMXL1_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.347163 (rank : 257)
Query Neighborhood Hits	470	Target Neighborhood Hits	257	Shared Neighborhood Hits	193
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

DNAI1_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.213372 (rank : 334)
Query Neighborhood Hits	470	Target Neighborhood Hits	148	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UI46, Q9UEZ8	Gene names	DNAI1
Domain Architecture
Description	Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1).

DTX3_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.088051 (rank : 521)
Query Neighborhood Hits	470	Target Neighborhood Hits	198	Shared Neighborhood Hits	109
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.088601 (rank : 519)
Query Neighborhood Hits	470	Target Neighborhood Hits	202	Shared Neighborhood Hits	111
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

EMAL1_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.461217 (rank : 217)
Query Neighborhood Hits	470	Target Neighborhood Hits	214	Shared Neighborhood Hits	183
SwissProt Accessions	O00423	Gene names	EML1, EMAP1, EMAPL, EMAPL1
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1).

ERMAP_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.107381 (rank : 481)
Query Neighborhood Hits	470	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.097895 (rank : 498)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

FBX16_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.081888 (rank : 530)
Query Neighborhood Hits	470	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FBX16_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.074701 (rank : 541)
Query Neighborhood Hits	470	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

FBXW5_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.287558 (rank : 284)
Query Neighborhood Hits	470	Target Neighborhood Hits	156	Shared Neighborhood Hits	120
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBXW5_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.304128 (rank : 277)
Query Neighborhood Hits	470	Target Neighborhood Hits	159	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

FBXW8_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.321490 (rank : 266)
Query Neighborhood Hits	470	Target Neighborhood Hits	192	Shared Neighborhood Hits	128
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

IF140_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.096734 (rank : 499)
Query Neighborhood Hits	470	Target Neighborhood Hits	111	Shared Neighborhood Hits	60
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

IFT80_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.349721 (rank : 256)
Query Neighborhood Hits	470	Target Neighborhood Hits	195	Shared Neighborhood Hits	154
SwissProt Accessions	Q9P2H3	Gene names	IFT80, KIAA1374, WDR56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

IFT80_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.359484 (rank : 254)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	154
SwissProt Accessions	Q8K057	Gene names	Ift80, Wdr56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

MEFV_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.125476 (rank : 459)
Query Neighborhood Hits	470	Target Neighborhood Hits	431	Shared Neighborhood Hits	88
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.114280 (rank : 471)
Query Neighborhood Hits	470	Target Neighborhood Hits	236	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

NHLC1_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.053763 (rank : 577)
Query Neighborhood Hits	470	Target Neighborhood Hits	91	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.059682 (rank : 566)
Query Neighborhood Hits	470	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NOL10_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.054562 (rank : 576)
Query Neighborhood Hits	470	Target Neighborhood Hits	254	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NOL10_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.058031 (rank : 571)
Query Neighborhood Hits	470	Target Neighborhood Hits	206	Shared Neighborhood Hits	54
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NUP37_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.352421 (rank : 255)
Query Neighborhood Hits	470	Target Neighborhood Hits	153	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NFH4, Q9H644	Gene names	NUP37
Domain Architecture
Description	Nucleoporin Nup37 (p37).

NUP37_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.370505 (rank : 247)
Query Neighborhood Hits	470	Target Neighborhood Hits	159	Shared Neighborhood Hits	140
SwissProt Accessions	Q9CWU9	Gene names	Nup37
Domain Architecture
Description	Nucleoporin Nup37.

NUP43_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.374126 (rank : 246)
Query Neighborhood Hits	470	Target Neighborhood Hits	198	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NFH3, Q9H8S0	Gene names	NUP43
Domain Architecture
Description	Nucleoporin Nup43 (p42).

NUP43_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.377804 (rank : 243)
Query Neighborhood Hits	470	Target Neighborhood Hits	193	Shared Neighborhood Hits	160
SwissProt Accessions	P59235	Gene names	Nup43
Domain Architecture
Description	Nucleoporin Nup43.

PCGF2_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.076881 (rank : 539)
Query Neighborhood Hits	470	Target Neighborhood Hits	222	Shared Neighborhood Hits	93
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.076507 (rank : 540)
Query Neighborhood Hits	470	Target Neighborhood Hits	213	Shared Neighborhood Hits	91
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PDZK4_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.070453 (rank : 545)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.070219 (rank : 547)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PI3R4_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.168246 (rank : 413)
Query Neighborhood Hits	470	Target Neighborhood Hits	534	Shared Neighborhood Hits	134
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

PI3R4_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.155375 (rank : 429)
Query Neighborhood Hits	470	Target Neighborhood Hits	535	Shared Neighborhood Hits	127
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

PML_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.072181 (rank : 544)
Query Neighborhood Hits	470	Target Neighborhood Hits	248	Shared Neighborhood Hits	94
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.078372 (rank : 534)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	105
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PPWD1_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.137818 (rank : 449)
Query Neighborhood Hits	470	Target Neighborhood Hits	136	Shared Neighborhood Hits	94
SwissProt Accessions	Q96BP3, Q15002, Q7KZ89	Gene names	PPWD1, KIAA0073
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PPWD1_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.133058 (rank : 451)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PREB_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.297845 (rank : 281)
Query Neighborhood Hits	470	Target Neighborhood Hits	156	Shared Neighborhood Hits	134
SwissProt Accessions	Q9WUQ2, Q9QZ99	Gene names	Preb, Sec12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

RAD18_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.098944 (rank : 497)
Query Neighborhood Hits	470	Target Neighborhood Hits	284	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.105645 (rank : 485)
Query Neighborhood Hits	470	Target Neighborhood Hits	230	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RBBP6_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.057855 (rank : 572)
Query Neighborhood Hits	470	Target Neighborhood Hits	1014	Shared Neighborhood Hits	130
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RFPL1_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.117251 (rank : 468)
Query Neighborhood Hits	470	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.120797 (rank : 465)
Query Neighborhood Hits	470	Target Neighborhood Hits	126	Shared Neighborhood Hits	92
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.121246 (rank : 463)
Query Neighborhood Hits	470	Target Neighborhood Hits	134	Shared Neighborhood Hits	94
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RING1_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.141677 (rank : 443)
Query Neighborhood Hits	470	Target Neighborhood Hits	219	Shared Neighborhood Hits	128
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.139563 (rank : 446)
Query Neighborhood Hits	470	Target Neighborhood Hits	220	Shared Neighborhood Hits	129
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.131137 (rank : 454)
Query Neighborhood Hits	470	Target Neighborhood Hits	201	Shared Neighborhood Hits	123
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.131188 (rank : 453)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	123
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN141_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.090382 (rank : 515)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	116
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.090484 (rank : 514)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	116
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.105649 (rank : 484)
Query Neighborhood Hits	470	Target Neighborhood Hits	162	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.104593 (rank : 489)
Query Neighborhood Hits	470	Target Neighborhood Hits	161	Shared Neighborhood Hits	106
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN152_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.055907 (rank : 575)
Query Neighborhood Hits	470	Target Neighborhood Hits	107	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.058356 (rank : 568)
Query Neighborhood Hits	470	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN169_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.104198 (rank : 490)
Query Neighborhood Hits	470	Target Neighborhood Hits	203	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.092321 (rank : 510)
Query Neighborhood Hits	470	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.082444 (rank : 529)
Query Neighborhood Hits	470	Target Neighborhood Hits	119	Shared Neighborhood Hits	80
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF8_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.142935 (rank : 439)
Query Neighborhood Hits	470	Target Neighborhood Hits	622	Shared Neighborhood Hits	176
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RPTOR_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.198107 (rank : 360)
Query Neighborhood Hits	470	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

RPTOR_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.180038 (rank : 395)
Query Neighborhood Hits	470	Target Neighborhood Hits	129	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

SEH1L_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.416583 (rank : 226)
Query Neighborhood Hits	470	Target Neighborhood Hits	145	Shared Neighborhood Hits	125
SwissProt Accessions	Q96EE3, Q8NFU6, Q96MH3, Q9C069	Gene names	SEH1L, SEC13L, SEH1
Domain Architecture
Description	Nucleoporin SEH1-like (SEC13-like protein).

SPRY4_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.092156 (rank : 511)
Query Neighborhood Hits	470	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.095839 (rank : 503)
Query Neighborhood Hits	470	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

STB5L_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.107508 (rank : 480)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STB5L_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.108085 (rank : 478)
Query Neighborhood Hits	470	Target Neighborhood Hits	138	Shared Neighborhood Hits	94
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STXB5_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.105562 (rank : 486)
Query Neighborhood Hits	470	Target Neighborhood Hits	167	Shared Neighborhood Hits	107
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

STXB5_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.093973 (rank : 505)
Query Neighborhood Hits	470	Target Neighborhood Hits	161	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

TF3C2_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.085280 (rank : 526)
Query Neighborhood Hits	470	Target Neighborhood Hits	168	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TF3C2_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.099170 (rank : 496)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

TIF1B_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.052145 (rank : 582)
Query Neighborhood Hits	470	Target Neighborhood Hits	312	Shared Neighborhood Hits	81
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.051133 (rank : 583)
Query Neighborhood Hits	470	Target Neighborhood Hits	276	Shared Neighborhood Hits	80
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.067653 (rank : 552)
Query Neighborhood Hits	470	Target Neighborhood Hits	410	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.065694 (rank : 557)
Query Neighborhood Hits	470	Target Neighborhood Hits	498	Shared Neighborhood Hits	88
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TOPRS_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.065140 (rank : 559)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 579)	NC score	0.068652 (rank : 549)
Query Neighborhood Hits	470	Target Neighborhood Hits	263	Shared Neighborhood Hits	101
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TR95_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.096628 (rank : 501)
Query Neighborhood Hits	470	Target Neighborhood Hits	95	Shared Neighborhood Hits	78
SwissProt Accessions	Q6PGF3	Gene names	Thrap5
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

TRAF1_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.139611 (rank : 445)
Query Neighborhood Hits	470	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

TRI14_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.119345 (rank : 466)
Query Neighborhood Hits	470	Target Neighborhood Hits	143	Shared Neighborhood Hits	74
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.121067 (rank : 464)
Query Neighborhood Hits	470	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI16_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.108290 (rank : 476)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	76
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.107085 (rank : 482)
Query Neighborhood Hits	470	Target Neighborhood Hits	196	Shared Neighborhood Hits	71
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI27_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.167385 (rank : 414)
Query Neighborhood Hits	470	Target Neighborhood Hits	273	Shared Neighborhood Hits	153
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.167342 (rank : 415)
Query Neighborhood Hits	470	Target Neighborhood Hits	261	Shared Neighborhood Hits	153
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI29_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.104116 (rank : 491)
Query Neighborhood Hits	470	Target Neighborhood Hits	273	Shared Neighborhood Hits	80
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.106744 (rank : 483)
Query Neighborhood Hits	470	Target Neighborhood Hits	306	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI34_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.164682 (rank : 418)
Query Neighborhood Hits	470	Target Neighborhood Hits	332	Shared Neighborhood Hits	135
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI37_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.122725 (rank : 462)
Query Neighborhood Hits	470	Target Neighborhood Hits	307	Shared Neighborhood Hits	128
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.122970 (rank : 461)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	128
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI42_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.086895 (rank : 522)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.105281 (rank : 487)
Query Neighborhood Hits	470	Target Neighborhood Hits	393	Shared Neighborhood Hits	78
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.108147 (rank : 477)
Query Neighborhood Hits	470	Target Neighborhood Hits	327	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI45_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.077821 (rank : 535)
Query Neighborhood Hits	470	Target Neighborhood Hits	155	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI56_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.142240 (rank : 441)
Query Neighborhood Hits	470	Target Neighborhood Hits	339	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.140829 (rank : 444)
Query Neighborhood Hits	470	Target Neighborhood Hits	255	Shared Neighborhood Hits	142
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TSCC1_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.320214 (rank : 267)
Query Neighborhood Hits	470	Target Neighborhood Hits	160	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K0G5	Gene names	Tssc1
Domain Architecture	No domain graphic available
Description	Protein TSSC1.

TSSC1_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.314283 (rank : 274)
Query Neighborhood Hits	470	Target Neighborhood Hits	157	Shared Neighborhood Hits	130
SwissProt Accessions	Q53HC9, O43179, Q53S19, Q53SG2	Gene names	TSSC1
Domain Architecture	No domain graphic available
Description	Protein TSSC1 (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) (Tumor-suppressing STF cDNA 1 protein).

TULP4_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.067353 (rank : 554)
Query Neighborhood Hits	470	Target Neighborhood Hits	426	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TULP4_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.079030 (rank : 533)
Query Neighborhood Hits	470	Target Neighborhood Hits	247	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

UHRF1_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.086426 (rank : 524)
Query Neighborhood Hits	470	Target Neighborhood Hits	272	Shared Neighborhood Hits	131
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.085923 (rank : 525)
Query Neighborhood Hits	470	Target Neighborhood Hits	278	Shared Neighborhood Hits	134
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UTP18_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.307381 (rank : 276)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

UTP18_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.239211 (rank : 303)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	98
SwissProt Accessions	Q5SSI6	Gene names	Utp18, Wdr50
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

WD21A_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.319792 (rank : 268)
Query Neighborhood Hits	470	Target Neighborhood Hits	136	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WV16, Q86U31, Q96K22, Q9Y4P5	Gene names	WDR21A, WDR21
Domain Architecture
Description	WD repeat protein 21A.

WDR13_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.433815 (rank : 222)
Query Neighborhood Hits	470	Target Neighborhood Hits	186	Shared Neighborhood Hits	166
SwissProt Accessions	Q9H1Z4, Q9BUL7, Q9NWW4	Gene names	WDR13
Domain Architecture
Description	WD repeat protein 13.

WDR13_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.420203 (rank : 225)
Query Neighborhood Hits	470	Target Neighborhood Hits	195	Shared Neighborhood Hits	170
SwissProt Accessions	Q91V09	Gene names	Wdr13
Domain Architecture
Description	WD repeat protein 13.

WDR19_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.079137 (rank : 532)
Query Neighborhood Hits	470	Target Neighborhood Hits	88	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEZ3, Q8N5B4, Q9H5S0, Q9HCD4	Gene names	WDR19, KIAA1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

WDR19_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.076972 (rank : 538)
Query Neighborhood Hits	470	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q3UGF1, Q6ZPK8, Q80VQ6, Q8C794, Q8K3R5	Gene names	Wdr19, Kiaa1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

WDR20_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.380863 (rank : 240)
Query Neighborhood Hits	470	Target Neighborhood Hits	249	Shared Neighborhood Hits	177
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

WDR20_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.395994 (rank : 232)
Query Neighborhood Hits	470	Target Neighborhood Hits	217	Shared Neighborhood Hits	175
SwissProt Accessions	Q9D5R2	Gene names	Wdr20
Domain Architecture
Description	WD repeat protein 20.

WDR34_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.126145 (rank : 458)
Query Neighborhood Hits	470	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	Q96EX3, Q5VXV4, Q9BV46	Gene names	WDR34
Domain Architecture
Description	WD repeat protein 34.

WDR34_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.136007 (rank : 450)
Query Neighborhood Hits	470	Target Neighborhood Hits	105	Shared Neighborhood Hits	79
SwissProt Accessions	Q5U4F6	Gene names	Wdr34
Domain Architecture	No domain graphic available
Description	WD repeat protein 34.

WDR35_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.118224 (rank : 467)
Query Neighborhood Hits	470	Target Neighborhood Hits	132	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

WDR35_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.101970 (rank : 494)
Query Neighborhood Hits	470	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

WDR46_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.222572 (rank : 317)
Query Neighborhood Hits	470	Target Neighborhood Hits	243	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WDR4_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.315709 (rank : 271)
Query Neighborhood Hits	470	Target Neighborhood Hits	145	Shared Neighborhood Hits	130
SwissProt Accessions	P57081, Q9HCR3	Gene names	WDR4
Domain Architecture
Description	WD repeat protein 4.

WDR4_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.318246 (rank : 269)
Query Neighborhood Hits	470	Target Neighborhood Hits	136	Shared Neighborhood Hits	124
SwissProt Accessions	Q9EP82	Gene names	Wdr4
Domain Architecture
Description	WD repeat protein 4.

WDR53_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.546064 (rank : 187)
Query Neighborhood Hits	470	Target Neighborhood Hits	251	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z5U6	Gene names	WDR53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WDR53_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.545794 (rank : 188)
Query Neighborhood Hits	470	Target Neighborhood Hits	254	Shared Neighborhood Hits	209
SwissProt Accessions	Q9DB94	Gene names	Wdr53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WDR54_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.101279 (rank : 495)
Query Neighborhood Hits	470	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H977, Q53H85, Q86V45	Gene names	WDR54
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

WDR54_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.156115 (rank : 428)
Query Neighborhood Hits	470	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

WDR55_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.546396 (rank : 186)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	188
SwissProt Accessions	Q9H6Y2	Gene names	WDR55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

WDR55_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.539595 (rank : 194)
Query Neighborhood Hits	470	Target Neighborhood Hits	236	Shared Neighborhood Hits	190
SwissProt Accessions	Q9CX97	Gene names	Wdr55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

WDR68_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.229228 (rank : 311)
Query Neighborhood Hits	470	Target Neighborhood Hits	121	Shared Neighborhood Hits	106
SwissProt Accessions	P61962, O15491, Q9DAE4	Gene names	WDR68, HAN11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR68_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.229228 (rank : 312)
Query Neighborhood Hits	470	Target Neighborhood Hits	121	Shared Neighborhood Hits	106
SwissProt Accessions	P61963, O15491, Q3TMV9, Q9DAE4	Gene names	Wdr68, Han11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR72_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.316860 (rank : 270)
Query Neighborhood Hits	470	Target Neighborhood Hits	167	Shared Neighborhood Hits	134
SwissProt Accessions	Q3MJ13, Q7Z3I3, Q8N8X2	Gene names	WDR72
Domain Architecture	No domain graphic available
Description	WD repeat protein 72.

WDR75_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.449194 (rank : 221)
Query Neighborhood Hits	470	Target Neighborhood Hits	193	Shared Neighborhood Hits	158
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

WDR76_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.072874 (rank : 543)
Query Neighborhood Hits	470	Target Neighborhood Hits	73	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H967	Gene names	WDR76
Domain Architecture	No domain graphic available
Description	WD repeat protein 76.

WDR8_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.144708 (rank : 438)
Query Neighborhood Hits	470	Target Neighborhood Hits	69	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P2S5, Q5T0D6, Q9BUH7, Q9NTK7, Q9NX56	Gene names	WDR8
Domain Architecture
Description	WD repeat protein 8.

WDR8_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.132564 (rank : 452)
Query Neighborhood Hits	470	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JM98	Gene names	Wdr8, Dd57
Domain Architecture
Description	WD repeat protein 8.

WIPI1_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.061914 (rank : 564)
Query Neighborhood Hits	470	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q5MNZ9, Q8IXM5, Q9NWF8	Gene names	WIPI1, WIPI49
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa) (Atg18 protein homolog).

WIPI1_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.073863 (rank : 542)
Query Neighborhood Hits	470	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R3E3, Q8BGE1, Q8R1A9, Q8R1C7	Gene names	Wipi1, D11Ertd498e
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa).

WIPI2_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.059201 (rank : 567)
Query Neighborhood Hits	470	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4P8, Q5MNZ8, Q6FI96, Q75L50, Q96IE4, Q9Y364	Gene names	WIPI2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2).

WIPI2_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.053154 (rank : 578)
Query Neighborhood Hits	470	Target Neighborhood Hits	55	Shared Neighborhood Hits	38
SwissProt Accessions	Q80W47	Gene names	Wipi2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2).

WIPI3_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.052239 (rank : 580)
Query Neighborhood Hits	470	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5MNZ6, O95328, Q6IBN2	Gene names	WDR45L, WIPI3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein) (WIPI49-like protein).

WIPI3_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.052670 (rank : 579)
Query Neighborhood Hits	470	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CR39, Q3U924	Gene names	Wdr45l, Wipi3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein).

Hits sorted by NC score

TRAF7_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	470	Target Neighborhood Hits	470	Shared Neighborhood Hits	470
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.997976 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	470	Target Neighborhood Hits	482	Shared Neighborhood Hits	462
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

FBW1B_HUMAN
NC score	0.834474 (rank : 3)	θ value	3.74554e-30 (rank : 5)
Query Neighborhood Hits	470	Target Neighborhood Hits	327	Shared Neighborhood Hits	248
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBXW7_MOUSE
NC score	0.833231 (rank : 4)	θ value	1.16434e-31 (rank : 4)
Query Neighborhood Hits	470	Target Neighborhood Hits	365	Shared Neighborhood Hits	252
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBW1A_HUMAN
NC score	0.832984 (rank : 5)	θ value	2.42779e-29 (rank : 6)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

FBXW7_HUMAN
NC score	0.830931 (rank : 6)	θ value	1.16434e-31 (rank : 3)
Query Neighborhood Hits	470	Target Neighborhood Hits	433	Shared Neighborhood Hits	253
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

LIS1_HUMAN
NC score	0.822445 (rank : 7)	θ value	6.18819e-25 (rank : 7)
Query Neighborhood Hits	470	Target Neighborhood Hits	333	Shared Neighborhood Hits	250
SwissProt Accessions	P43034, Q8WZ88, Q8WZ89	Gene names	PAFAH1B1, LIS1, MDCR, PAFAHA
Domain Architecture
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

LIS1_MOUSE
NC score	0.822419 (rank : 8)	θ value	6.18819e-25 (rank : 8)
Query Neighborhood Hits	470	Target Neighborhood Hits	336	Shared Neighborhood Hits	252
SwissProt Accessions	P63005, O35592, P43035, P81692, Q9R2A6	Gene names	Pafah1b1, Lis-1, Lis1, Pafaha
Domain Architecture	No domain graphic available
Description	Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1).

WDR69_HUMAN
NC score	0.809830 (rank : 9)	θ value	1.13037e-18 (rank : 11)
Query Neighborhood Hits	470	Target Neighborhood Hits	324	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N136, Q6ZRY1, Q8N776	Gene names	WDR69
Domain Architecture	No domain graphic available
Description	WD repeat protein 69.

PLRG1_HUMAN
NC score	0.803833 (rank : 10)	θ value	3.18553e-13 (rank : 21)
Query Neighborhood Hits	470	Target Neighborhood Hits	318	Shared Neighborhood Hits	250
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

PLRG1_MOUSE
NC score	0.801937 (rank : 11)	θ value	1.58096e-12 (rank : 24)
Query Neighborhood Hits	470	Target Neighborhood Hits	308	Shared Neighborhood Hits	248
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

WDR5_HUMAN
NC score	0.796858 (rank : 12)	θ value	2.69047e-20 (rank : 9)
Query Neighborhood Hits	470	Target Neighborhood Hits	341	Shared Neighborhood Hits	252
SwissProt Accessions	P61964, Q91VA5, Q9NWX7, Q9UGP9	Gene names	WDR5, BIG3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein).

WDR5_MOUSE
NC score	0.796858 (rank : 13)	θ value	2.69047e-20 (rank : 10)
Query Neighborhood Hits	470	Target Neighborhood Hits	341	Shared Neighborhood Hits	252
SwissProt Accessions	P61965, Q91VA5, Q922C9, Q9NWX7, Q9UGP9	Gene names	Wdr5, Big, Big3
Domain Architecture
Description	WD repeat protein 5 (BMP2-induced 3-kb gene protein) (WD repeat protein BIG-3).

WDR57_HUMAN
NC score	0.795531 (rank : 14)	θ value	2.13179e-17 (rank : 13)
Query Neighborhood Hits	470	Target Neighborhood Hits	322	Shared Neighborhood Hits	253
SwissProt Accessions	Q96DI7, O75938, O95320	Gene names	WDR57, PRP8BP, SFP38
Domain Architecture	No domain graphic available
Description	WD repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5 snRNP- specific 40 kDa protein) (38 kDa-splicing factor).

WDR57_MOUSE
NC score	0.795074 (rank : 15)	θ value	1.24977e-17 (rank : 12)
Query Neighborhood Hits	470	Target Neighborhood Hits	323	Shared Neighborhood Hits	253
SwissProt Accessions	Q6PE01, Q3TEJ3, Q9DCX3	Gene names	Wdr57
Domain Architecture	No domain graphic available
Description	WD repeat protein 57.

NLE1_MOUSE
NC score	0.790761 (rank : 16)	θ value	4.02038e-16 (rank : 16)
Query Neighborhood Hits	470	Target Neighborhood Hits	332	Shared Neighborhood Hits	253
SwissProt Accessions	Q8VEJ4	Gene names	Nle1
Domain Architecture
Description	Notchless homolog 1.

NLE1_HUMAN
NC score	0.790134 (rank : 17)	θ value	3.07829e-16 (rank : 15)
Query Neighborhood Hits	470	Target Neighborhood Hits	334	Shared Neighborhood Hits	253
SwissProt Accessions	Q9NVX2, O60868, Q9BU54	Gene names	NLE1
Domain Architecture
Description	Notchless homolog 1.

WD51A_MOUSE
NC score	0.788105 (rank : 18)	θ value	2.60593e-15 (rank : 17)
Query Neighborhood Hits	470	Target Neighborhood Hits	342	Shared Neighborhood Hits	254
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

WD51A_HUMAN
NC score	0.785621 (rank : 19)	θ value	2.88119e-14 (rank : 19)
Query Neighborhood Hits	470	Target Neighborhood Hits	337	Shared Neighborhood Hits	252
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

GBLP_HUMAN
NC score	0.785241 (rank : 20)	θ value	1.9326e-10 (rank : 48)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	250
SwissProt Accessions	P63244, P25388, P99049	Gene names	GNB2L1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).

GBLP_MOUSE
NC score	0.785241 (rank : 21)	θ value	1.9326e-10 (rank : 49)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	250
SwissProt Accessions	P68040, P25388, P99049	Gene names	Gnb2l1, Gnb2-rs1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 2-like 1 (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) (p205) (12-3).

PRP4_HUMAN
NC score	0.783037 (rank : 22)	θ value	6.00763e-12 (rank : 27)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	249
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

PRP4_MOUSE
NC score	0.782705 (rank : 23)	θ value	7.84624e-12 (rank : 28)
Query Neighborhood Hits	470	Target Neighborhood Hits	308	Shared Neighborhood Hits	247
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

SPG16_HUMAN
NC score	0.780429 (rank : 24)	θ value	1.2105e-12 (rank : 22)
Query Neighborhood Hits	470	Target Neighborhood Hits	361	Shared Neighborhood Hits	255
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

WDR3_HUMAN
NC score	0.779954 (rank : 25)	θ value	6.21693e-09 (rank : 80)
Query Neighborhood Hits	470	Target Neighborhood Hits	334	Shared Neighborhood Hits	247
SwissProt Accessions	Q9UNX4	Gene names	WDR3
Domain Architecture
Description	WD repeat protein 3.

WDR48_HUMAN
NC score	0.777526 (rank : 26)	θ value	7.84624e-12 (rank : 29)
Query Neighborhood Hits	470	Target Neighborhood Hits	291	Shared Neighborhood Hits	241
SwissProt Accessions	Q8TAF3, Q63HJ2, Q658Y1, Q8N3Z1, Q9NSK8, Q9P279	Gene names	WDR48, KIAA1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48 (WD repeat endosomal protein) (p80).

WDR48_MOUSE
NC score	0.776261 (rank : 27)	θ value	1.74796e-11 (rank : 35)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	242
SwissProt Accessions	Q8BH57, Q80TD4, Q80XI0, Q8BRM0, Q8CBK0, Q922Z9, Q9CRR1, Q9CSL0	Gene names	Wdr48, Kiaa1449
Domain Architecture	No domain graphic available
Description	WD repeat protein 48.

TBL3_HUMAN
NC score	0.776120 (rank : 28)	θ value	7.34386e-10 (rank : 65)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	236
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

SPG16_MOUSE
NC score	0.775277 (rank : 29)	θ value	1.02475e-11 (rank : 31)
Query Neighborhood Hits	470	Target Neighborhood Hits	377	Shared Neighborhood Hits	250
SwissProt Accessions	Q8K450, Q8C450, Q9CPU8, Q9D522	Gene names	Spag16, Pf20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

WD51B_HUMAN
NC score	0.775067 (rank : 30)	θ value	1.33837e-11 (rank : 33)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	253
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WD51B_MOUSE
NC score	0.774817 (rank : 31)	θ value	8.11959e-09 (rank : 83)
Query Neighborhood Hits	470	Target Neighborhood Hits	321	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

WDR61_MOUSE
NC score	0.774093 (rank : 32)	θ value	1.02475e-11 (rank : 32)
Query Neighborhood Hits	470	Target Neighborhood Hits	331	Shared Neighborhood Hits	250
SwissProt Accessions	Q9ERF3, Q3U562, Q9CZP1	Gene names	Wdr61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

WDR61_HUMAN
NC score	0.773454 (rank : 33)	θ value	1.33837e-11 (rank : 34)
Query Neighborhood Hits	470	Target Neighborhood Hits	334	Shared Neighborhood Hits	251
SwissProt Accessions	Q9GZS3, Q6IA22, Q7Z4X4	Gene names	WDR61
Domain Architecture	No domain graphic available
Description	WD repeat protein 61 (Meiotic recombination REC14 protein homolog).

KTNB1_HUMAN
NC score	0.769548 (rank : 34)	θ value	2.52405e-10 (rank : 52)
Query Neighborhood Hits	470	Target Neighborhood Hits	349	Shared Neighborhood Hits	254
SwissProt Accessions	Q9BVA0, O60620	Gene names	KATNB1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

KTNB1_MOUSE
NC score	0.769423 (rank : 35)	θ value	2.52405e-10 (rank : 53)
Query Neighborhood Hits	470	Target Neighborhood Hits	356	Shared Neighborhood Hits	254
SwissProt Accessions	Q8BG40, Q8CD18, Q8R1J0, Q9CWV2	Gene names	Katnb1
Domain Architecture	No domain graphic available
Description	Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin).

TAF5_MOUSE
NC score	0.769419 (rank : 36)	θ value	7.34386e-10 (rank : 64)
Query Neighborhood Hits	470	Target Neighborhood Hits	366	Shared Neighborhood Hits	255
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5_HUMAN
NC score	0.768568 (rank : 37)	θ value	1.63604e-09 (rank : 71)
Query Neighborhood Hits	470	Target Neighborhood Hits	352	Shared Neighborhood Hits	255
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5L_HUMAN
NC score	0.767209 (rank : 38)	θ value	3.29651e-10 (rank : 56)
Query Neighborhood Hits	470	Target Neighborhood Hits	330	Shared Neighborhood Hits	252
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

TAF5L_MOUSE
NC score	0.766236 (rank : 39)	θ value	1.47974e-10 (rank : 44)
Query Neighborhood Hits	470	Target Neighborhood Hits	337	Shared Neighborhood Hits	252
SwissProt Accessions	Q91WQ5, Q8BTL5	Gene names	Taf5l, Paf65b
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

MORG1_MOUSE
NC score	0.765437 (rank : 40)	θ value	1.29631e-06 (rank : 116)
Query Neighborhood Hits	470	Target Neighborhood Hits	281	Shared Neighborhood Hits	241
SwissProt Accessions	Q9DAJ4, Q505C2, Q8VEB7, Q99JX9, Q9D235	Gene names	Morg1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

MORG1_HUMAN
NC score	0.765189 (rank : 41)	θ value	1.29631e-06 (rank : 115)
Query Neighborhood Hits	470	Target Neighborhood Hits	280	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BRX9, Q53FT6	Gene names	MORG1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase organizer 1 (MAPK organizer 1).

WDR31_MOUSE
NC score	0.764630 (rank : 42)	θ value	1.47974e-10 (rank : 45)
Query Neighborhood Hits	470	Target Neighborhood Hits	287	Shared Neighborhood Hits	239
SwissProt Accessions	Q9JHB4, Q3URZ0, Q9D3N4	Gene names	Wdr31
Domain Architecture
Description	WD repeat protein 31 (Spermatid WD repeat protein) (spWD).

WDR12_HUMAN
NC score	0.761710 (rank : 43)	θ value	3.29651e-10 (rank : 57)
Query Neighborhood Hits	470	Target Neighborhood Hits	300	Shared Neighborhood Hits	238
SwissProt Accessions	Q9GZL7, Q96HU0, Q9NV80, Q9NYI8	Gene names	WDR12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

U3IP2_MOUSE
NC score	0.761133 (rank : 44)	θ value	3.64472e-09 (rank : 76)
Query Neighborhood Hits	470	Target Neighborhood Hits	312	Shared Neighborhood Hits	234
SwissProt Accessions	Q91WM3, Q8CFB7	Gene names	Rnu3ip2, U3-55k
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

WDR12_MOUSE
NC score	0.761063 (rank : 45)	θ value	3.89403e-11 (rank : 39)
Query Neighborhood Hits	470	Target Neighborhood Hits	301	Shared Neighborhood Hits	240
SwissProt Accessions	Q9JJA4, Q9CST3, Q9JKF5	Gene names	Wdr12
Domain Architecture
Description	WD repeat protein 12 (YTM1 homolog).

U3IP2_HUMAN
NC score	0.759242 (rank : 46)	θ value	1.80886e-08 (rank : 90)
Query Neighborhood Hits	470	Target Neighborhood Hits	307	Shared Neighborhood Hits	235
SwissProt Accessions	O43818, Q8IZ30	Gene names	RNU3IP2, U355K
Domain Architecture
Description	U3 small nucleolar RNA-interacting protein 2 (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K).

PRP19_MOUSE
NC score	0.758102 (rank : 47)	θ value	4.0297e-08 (rank : 96)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	247
SwissProt Accessions	Q99KP6, Q3TP64, Q8BKZ5, Q8BVQ4	Gene names	Prpf19, Prp19, Snev
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (Nuclear matrix protein SNEV).

WDR31_HUMAN
NC score	0.757631 (rank : 48)	θ value	6.87365e-08 (rank : 99)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	238
SwissProt Accessions	Q8NA23, Q96EG8	Gene names	WDR31
Domain Architecture
Description	WD repeat protein 31.

PRP19_HUMAN
NC score	0.757478 (rank : 49)	θ value	1.17247e-07 (rank : 104)
Query Neighborhood Hits	470	Target Neighborhood Hits	333	Shared Neighborhood Hits	247
SwissProt Accessions	Q9UMS4	Gene names	PRPF19, NMP200, PRP19
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear matrix protein 200) (hPso4).

FBXW2_MOUSE
NC score	0.756278 (rank : 50)	θ value	1.06045e-08 (rank : 84)
Query Neighborhood Hits	470	Target Neighborhood Hits	249	Shared Neighborhood Hits	220
SwissProt Accessions	Q60584	Gene names	Fbxw2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

COPA_HUMAN
NC score	0.755837 (rank : 51)	θ value	4.30538e-10 (rank : 59)
Query Neighborhood Hits	470	Target Neighborhood Hits	297	Shared Neighborhood Hits	236
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

FBXW2_HUMAN
NC score	0.752505 (rank : 52)	θ value	6.87365e-08 (rank : 98)
Query Neighborhood Hits	470	Target Neighborhood Hits	260	Shared Neighborhood Hits	221
SwissProt Accessions	Q9UKT8, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3	Gene names	FBXW2, FBW2, FWD2
Domain Architecture
Description	F-box/WD repeat protein 2 (F-box and WD-40 domain protein 2) (MD6 protein).

APAF_MOUSE
NC score	0.748915 (rank : 53)	θ value	1.63604e-09 (rank : 69)
Query Neighborhood Hits	470	Target Neighborhood Hits	343	Shared Neighborhood Hits	251
SwissProt Accessions	O88879	Gene names	Apaf1
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

COPB2_HUMAN
NC score	0.748624 (rank : 54)	θ value	6.21693e-09 (rank : 78)
Query Neighborhood Hits	470	Target Neighborhood Hits	315	Shared Neighborhood Hits	245
SwissProt Accessions	P35606	Gene names	COPB2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

WDR71_HUMAN
NC score	0.748487 (rank : 55)	θ value	8.40245e-06 (rank : 137)
Query Neighborhood Hits	470	Target Neighborhood Hits	241	Shared Neighborhood Hits	215
SwissProt Accessions	Q9BRP4, Q4G165, Q53HS9, Q7Z500, Q8TBU6, Q9HAB6	Gene names	WDR71
Domain Architecture	No domain graphic available
Description	WD repeat protein 71 (Protein G-16).

COPB2_MOUSE
NC score	0.748486 (rank : 56)	θ value	6.21693e-09 (rank : 79)
Query Neighborhood Hits	470	Target Neighborhood Hits	315	Shared Neighborhood Hits	245
SwissProt Accessions	O55029, Q3U5Z9	Gene names	Copb2
Domain Architecture
Description	Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102).

APAF_HUMAN
NC score	0.748206 (rank : 57)	θ value	5.62301e-10 (rank : 61)
Query Neighborhood Hits	470	Target Neighborhood Hits	334	Shared Neighborhood Hits	250
SwissProt Accessions	O14727, O43297, Q7Z438, Q9BXZ6, Q9UBZ5, Q9UGN8, Q9UGN9, Q9UGP0, Q9UJ58, Q9UJ59, Q9UJ60, Q9UJ61, Q9UJ62, Q9UJ63, Q9UJ64, Q9UJ65, Q9UJ66, Q9UJ67, Q9UNC9	Gene names	APAF1, KIAA0413
Domain Architecture
Description	Apoptotic protease-activating factor 1 (Apaf-1).

WDR37_HUMAN
NC score	0.746134 (rank : 58)	θ value	8.97725e-08 (rank : 102)
Query Neighborhood Hits	470	Target Neighborhood Hits	303	Shared Neighborhood Hits	237
SwissProt Accessions	Q9Y2I8, Q5SW03, Q9NTJ6	Gene names	WDR37, KIAA0982
Domain Architecture
Description	WD repeat protein 37.

WDR37_MOUSE
NC score	0.744483 (rank : 59)	θ value	1.29631e-06 (rank : 118)
Query Neighborhood Hits	470	Target Neighborhood Hits	298	Shared Neighborhood Hits	235
SwissProt Accessions	Q8CBE3, Q80Y96, Q8CCL2	Gene names	Wdr37, Kiaa0982
Domain Architecture
Description	WD repeat protein 37.

GBB5_MOUSE
NC score	0.743484 (rank : 60)	θ value	3.08544e-08 (rank : 93)
Query Neighborhood Hits	470	Target Neighborhood Hits	298	Shared Neighborhood Hits	248
SwissProt Accessions	P62881, O35354, P54314, Q91WB3	Gene names	Gnb5
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBB5_HUMAN
NC score	0.742819 (rank : 61)	θ value	3.08544e-08 (rank : 92)
Query Neighborhood Hits	470	Target Neighborhood Hits	299	Shared Neighborhood Hits	248
SwissProt Accessions	O14775, Q9HAU9	Gene names	GNB5
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 5 (Transducin beta chain 5) (Gbeta5).

GBB4_HUMAN
NC score	0.741246 (rank : 62)	θ value	9.59137e-10 (rank : 66)
Query Neighborhood Hits	470	Target Neighborhood Hits	288	Shared Neighborhood Hits	241
SwissProt Accessions	Q9HAV0	Gene names	GNB4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

TBL1R_HUMAN
NC score	0.741181 (rank : 63)	θ value	3.89403e-11 (rank : 36)
Query Neighborhood Hits	470	Target Neighborhood Hits	327	Shared Neighborhood Hits	245
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1Y_HUMAN
NC score	0.741045 (rank : 64)	θ value	3.52202e-12 (rank : 26)
Query Neighborhood Hits	470	Target Neighborhood Hits	331	Shared Neighborhood Hits	245
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

TBL1R_MOUSE
NC score	0.741033 (rank : 65)	θ value	3.89403e-11 (rank : 37)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	245
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBLX_MOUSE
NC score	0.740448 (rank : 66)	θ value	3.89403e-11 (rank : 38)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	245
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

GBB4_MOUSE
NC score	0.740176 (rank : 67)	θ value	4.76016e-09 (rank : 77)
Query Neighborhood Hits	470	Target Neighborhood Hits	283	Shared Neighborhood Hits	239
SwissProt Accessions	P29387, Q3TJJ1, Q8R475, Q9JHX8	Gene names	Gnb4
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta 4 (Transducin beta chain 4).

PLAP_HUMAN
NC score	0.740148 (rank : 68)	θ value	1.63604e-09 (rank : 70)
Query Neighborhood Hits	470	Target Neighborhood Hits	266	Shared Neighborhood Hits	228
SwissProt Accessions	Q9Y263, Q53EU5, Q5VY33, Q9NUL8, Q9NVE9, Q9UF53, Q9Y5L1	Gene names	PLAA, PLAP
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP) (PLA2P).

PLAP_MOUSE
NC score	0.740059 (rank : 69)	θ value	1.38499e-08 (rank : 85)
Query Neighborhood Hits	470	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

TBL1X_HUMAN
NC score	0.739323 (rank : 70)	θ value	6.64225e-11 (rank : 41)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	245
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

AAMP_HUMAN
NC score	0.739139 (rank : 71)	θ value	0.0252991 (rank : 244)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	235
SwissProt Accessions	Q13685, Q8WUJ9, Q96H92	Gene names	AAMP
Domain Architecture
Description	Angio-associated migratory cell protein.

GBB1_HUMAN
NC score	0.738396 (rank : 72)	θ value	4.0297e-08 (rank : 94)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	238
SwissProt Accessions	P62873, P04697, P04901	Gene names	GNB1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB1_MOUSE
NC score	0.738396 (rank : 73)	θ value	4.0297e-08 (rank : 95)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	238
SwissProt Accessions	P62874, P04697, P04901	Gene names	Gnb1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 1 (Transducin beta chain 1).

GBB2_HUMAN
NC score	0.737699 (rank : 74)	θ value	8.11959e-09 (rank : 81)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	242
SwissProt Accessions	P62879, P11016, P54312	Gene names	GNB2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

GBB2_MOUSE
NC score	0.737699 (rank : 75)	θ value	8.11959e-09 (rank : 82)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	242
SwissProt Accessions	P62880, P11016, P54312	Gene names	Gnb2
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit).

SMU1_HUMAN
NC score	0.736496 (rank : 76)	θ value	2.88788e-06 (rank : 120)
Query Neighborhood Hits	470	Target Neighborhood Hits	311	Shared Neighborhood Hits	242
SwissProt Accessions	Q2TAY7, Q9BU59, Q9HA96, Q9NVD1	Gene names	SMU1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

SMU1_MOUSE
NC score	0.736496 (rank : 77)	θ value	2.88788e-06 (rank : 121)
Query Neighborhood Hits	470	Target Neighborhood Hits	311	Shared Neighborhood Hits	242
SwissProt Accessions	Q3UKJ7, Q6PFR6, Q8BMY4, Q9D1I8, Q9JJ70	Gene names	Smu1
Domain Architecture	No domain graphic available
Description	Smu-1 suppressor of mec-8 and unc-52 protein homolog.

PRP17_MOUSE
NC score	0.734885 (rank : 78)	θ value	9.59137e-10 (rank : 67)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	231
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

PRP17_HUMAN
NC score	0.734158 (rank : 79)	θ value	2.13673e-09 (rank : 72)
Query Neighborhood Hits	470	Target Neighborhood Hits	297	Shared Neighborhood Hits	232
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

GBB3_HUMAN
NC score	0.733865 (rank : 80)	θ value	3.08544e-08 (rank : 91)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	241
SwissProt Accessions	P16520, Q9BQC0	Gene names	GNB3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

WSB2_MOUSE
NC score	0.733432 (rank : 81)	θ value	4.92598e-06 (rank : 131)
Query Neighborhood Hits	470	Target Neighborhood Hits	306	Shared Neighborhood Hits	241
SwissProt Accessions	O54929, Q9R1M8	Gene names	Wsb2, Swip2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (SOCS box- containing WD protein SWiP-2).

GBB3_MOUSE
NC score	0.733218 (rank : 82)	θ value	1.80886e-08 (rank : 89)
Query Neighborhood Hits	470	Target Neighborhood Hits	283	Shared Neighborhood Hits	241
SwissProt Accessions	Q61011	Gene names	Gnb3
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 3 (Transducin beta chain 3).

WSB2_HUMAN
NC score	0.732532 (rank : 83)	θ value	6.43352e-06 (rank : 134)
Query Neighborhood Hits	470	Target Neighborhood Hits	308	Shared Neighborhood Hits	241
SwissProt Accessions	Q9NYS7, Q9NRX9	Gene names	WSB2
Domain Architecture
Description	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein).

UTP15_MOUSE
NC score	0.728987 (rank : 84)	θ value	0.000121331 (rank : 155)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	246
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

WDR17_HUMAN
NC score	0.727784 (rank : 85)	θ value	1.53129e-07 (rank : 107)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	246
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

FZR_MOUSE
NC score	0.724994 (rank : 86)	θ value	1.9326e-10 (rank : 47)
Query Neighborhood Hits	470	Target Neighborhood Hits	283	Shared Neighborhood Hits	234
SwissProt Accessions	Q9R1K5	Gene names	Fzr1, Fyr, Fzr
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog).

UTP15_HUMAN
NC score	0.724225 (rank : 87)	θ value	4.1701e-05 (rank : 149)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	241
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

FZR_HUMAN
NC score	0.723358 (rank : 88)	θ value	2.52405e-10 (rank : 51)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	234
SwissProt Accessions	Q9UM11, O75869, Q86U66, Q96NW8, Q9UI96, Q9ULH8, Q9UM10, Q9UNQ1, Q9Y2T8	Gene names	FZR1, CDH1, FYR, FZR, KIAA1242
Domain Architecture
Description	Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1) (CDC20-like protein 1).

PWP2_MOUSE
NC score	0.723346 (rank : 89)	θ value	1.29631e-06 (rank : 117)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	246
SwissProt Accessions	Q8BU03, Q8BTR0	Gene names	Pwp2h
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

STRAP_MOUSE
NC score	0.721976 (rank : 90)	θ value	1.43324e-05 (rank : 144)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	225
SwissProt Accessions	Q9Z1Z2	Gene names	Strap, Unrip
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein).

WDR47_MOUSE
NC score	0.721472 (rank : 91)	θ value	3.29651e-10 (rank : 58)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	Q8CGF6, Q80TP4	Gene names	Wdr47, Kiaa0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

WDR47_HUMAN
NC score	0.720915 (rank : 92)	θ value	5.62301e-10 (rank : 62)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	220
SwissProt Accessions	O94967, Q8IXT7, Q8IYU9	Gene names	WDR47, KIAA0893
Domain Architecture	No domain graphic available
Description	WD repeat protein 47.

STRAP_HUMAN
NC score	0.720873 (rank : 93)	θ value	8.40245e-06 (rank : 136)
Query Neighborhood Hits	470	Target Neighborhood Hits	272	Shared Neighborhood Hits	225
SwissProt Accessions	Q9Y3F4, Q9UQC8	Gene names	STRAP, MAWD, UNRIP
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein) (WD-40 repeat protein PT-WD) (MAP activator with WD repeats).

PK1IP_MOUSE
NC score	0.720850 (rank : 94)	θ value	5.26297e-08 (rank : 97)
Query Neighborhood Hits	470	Target Neighborhood Hits	313	Shared Neighborhood Hits	231
SwissProt Accessions	Q9DCE5, Q3UBK7, Q80UT4, Q8C5N6, Q923K2, Q9D3E9	Gene names	Pak1ip1
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (Putative PAK inhibitor Skb15).

WDR39_HUMAN
NC score	0.720043 (rank : 95)	θ value	8.97725e-08 (rank : 103)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	225
SwissProt Accessions	O76071	Gene names	WDR39, CIAO1
Domain Architecture
Description	WD repeat protein 39 (Ciao 1 protein).

PWP2_HUMAN
NC score	0.719768 (rank : 96)	θ value	6.43352e-06 (rank : 133)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	246
SwissProt Accessions	Q15269, Q96A77	Gene names	PWP2H, PWP2
Domain Architecture
Description	Periodic tryptophan protein 2 homolog.

WSB1_HUMAN
NC score	0.716673 (rank : 97)	θ value	5.44631e-05 (rank : 152)
Query Neighborhood Hits	470	Target Neighborhood Hits	337	Shared Neighborhood Hits	238
SwissProt Accessions	Q9Y6I7, Q9NRB1, Q9UBH9, Q9UNN6	Gene names	WSB1, SWIP1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box- containing WD protein SWiP-1).

PK1IP_HUMAN
NC score	0.713877 (rank : 98)	θ value	3.77169e-06 (rank : 126)
Query Neighborhood Hits	470	Target Neighborhood Hits	277	Shared Neighborhood Hits	222
SwissProt Accessions	Q9NWT1, Q5T4J2, Q96QJ8, Q96T87	Gene names	PAK1IP1, PIP1, WDR84
Domain Architecture	No domain graphic available
Description	p21-activated protein kinase-interacting protein 1 (PAK1-interacting protein 1) (PAK/PLC-interacting protein 1) (hPIP1) (WD repeat protein 84).

WSB1_MOUSE
NC score	0.713688 (rank : 99)	θ value	5.44631e-05 (rank : 153)
Query Neighborhood Hits	470	Target Neighborhood Hits	313	Shared Neighborhood Hits	237
SwissProt Accessions	O54927	Gene names	Wsb1
Domain Architecture
Description	WD repeat and SOCS box-containing protein 1 (WSB-1).

PEX7_MOUSE
NC score	0.711040 (rank : 100)	θ value	3.19293e-05 (rank : 146)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	235
SwissProt Accessions	P97865	Gene names	Pex7
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

A16L1_HUMAN
NC score	0.708997 (rank : 101)	θ value	1.25267e-09 (rank : 68)
Query Neighborhood Hits	470	Target Neighborhood Hits	664	Shared Neighborhood Hits	257
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

TEP1_HUMAN
NC score	0.707739 (rank : 102)	θ value	2.13673e-09 (rank : 73)
Query Neighborhood Hits	470	Target Neighborhood Hits	371	Shared Neighborhood Hits	251
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

PEX7_HUMAN
NC score	0.707104 (rank : 103)	θ value	1.43324e-05 (rank : 143)
Query Neighborhood Hits	470	Target Neighborhood Hits	275	Shared Neighborhood Hits	229
SwissProt Accessions	O00628	Gene names	PEX7, PTS2R
Domain Architecture
Description	Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7).

CDC20_HUMAN
NC score	0.701476 (rank : 104)	θ value	8.40245e-06 (rank : 135)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	223
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

WDR16_MOUSE
NC score	0.700028 (rank : 105)	θ value	1.53129e-07 (rank : 106)
Query Neighborhood Hits	470	Target Neighborhood Hits	269	Shared Neighborhood Hits	227
SwissProt Accessions	Q5F201, Q5F200, Q9D432, Q9DA68	Gene names	WDR16
Domain Architecture	No domain graphic available
Description	WD repeat protein 16.

CDC20_MOUSE
NC score	0.697769 (rank : 106)	θ value	1.09739e-05 (rank : 138)
Query Neighborhood Hits	470	Target Neighborhood Hits	325	Shared Neighborhood Hits	223
SwissProt Accessions	Q9JJ66, Q3TGP1, Q8BPG4, Q99LK3	Gene names	Cdc20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC) (mmCdc20).

WDR16_HUMAN
NC score	0.697286 (rank : 107)	θ value	3.77169e-06 (rank : 129)
Query Neighborhood Hits	470	Target Neighborhood Hits	275	Shared Neighborhood Hits	228
SwissProt Accessions	Q8N1V2, Q5DX23, Q8TC73, Q8TCI3	Gene names	WDR16, WDRPUH
Domain Architecture	No domain graphic available
Description	WD repeat protein 16 (WD40-repeat protein up-regulated in HCC).

WDR18_HUMAN
NC score	0.693942 (rank : 108)	θ value	3.19293e-05 (rank : 148)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	223
SwissProt Accessions	Q9BV38, O60390, Q9BWR2	Gene names	WDR18
Domain Architecture
Description	WD repeat protein 18.

A16L1_MOUSE
NC score	0.688415 (rank : 109)	θ value	8.97725e-08 (rank : 100)
Query Neighborhood Hits	470	Target Neighborhood Hits	776	Shared Neighborhood Hits	260
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

CSTF1_HUMAN
NC score	0.686798 (rank : 110)	θ value	0.000786445 (rank : 177)
Query Neighborhood Hits	470	Target Neighborhood Hits	266	Shared Neighborhood Hits	220
SwissProt Accessions	Q05048	Gene names	CSTF1
Domain Architecture
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

CSTF1_MOUSE
NC score	0.685090 (rank : 111)	θ value	0.00298849 (rank : 196)
Query Neighborhood Hits	470	Target Neighborhood Hits	266	Shared Neighborhood Hits	218
SwissProt Accessions	Q99LC2, Q3UMB8, Q8BJW1, Q9CSU8	Gene names	Cstf1
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 50 kDa subunit (CSTF 50 kDa subunit) (CF-1 50 kDa subunit) (CstF-50).

WDR36_HUMAN
NC score	0.679068 (rank : 112)	θ value	0.00390308 (rank : 210)
Query Neighborhood Hits	470	Target Neighborhood Hits	274	Shared Neighborhood Hits	228
SwissProt Accessions	Q8NI36, Q8N1Q2	Gene names	WDR36
Domain Architecture
Description	WD repeat protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP).

STRN3_HUMAN
NC score	0.677141 (rank : 113)	θ value	1.133e-10 (rank : 43)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	228
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

STRN4_MOUSE
NC score	0.674900 (rank : 114)	θ value	2.61198e-07 (rank : 108)
Query Neighborhood Hits	470	Target Neighborhood Hits	324	Shared Neighborhood Hits	238
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

WDR18_MOUSE
NC score	0.674889 (rank : 115)	θ value	4.1701e-05 (rank : 150)
Query Neighborhood Hits	470	Target Neighborhood Hits	239	Shared Neighborhood Hits	213
SwissProt Accessions	Q4VBE8	Gene names	Wdr18
Domain Architecture	No domain graphic available
Description	WD repeat protein 18.

STRN3_MOUSE
NC score	0.673473 (rank : 116)	θ value	3.29651e-10 (rank : 55)
Query Neighborhood Hits	470	Target Neighborhood Hits	309	Shared Neighborhood Hits	226
SwissProt Accessions	Q9ERG2	Gene names	Strn3, Gs2na, Sg2na
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

STRN4_HUMAN
NC score	0.672916 (rank : 117)	θ value	1.17247e-07 (rank : 105)
Query Neighborhood Hits	470	Target Neighborhood Hits	325	Shared Neighborhood Hits	239
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

TEP1_MOUSE
NC score	0.672391 (rank : 118)	θ value	0.000121331 (rank : 154)
Query Neighborhood Hits	470	Target Neighborhood Hits	344	Shared Neighborhood Hits	243
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

THOC3_MOUSE
NC score	0.670582 (rank : 119)	θ value	0.279714 (rank : 319)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	232
SwissProt Accessions	Q8VE80, Q9CWI8	Gene names	Thoc3
Domain Architecture
Description	THO complex subunit 3 (Tho3).

THOC3_HUMAN
NC score	0.669126 (rank : 120)	θ value	0.279714 (rank : 318)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	230
SwissProt Accessions	Q96J01	Gene names	THOC3
Domain Architecture
Description	THO complex subunit 3 (Tho3) (TEX1 homolog).

STRN_MOUSE
NC score	0.666733 (rank : 121)	θ value	2.61198e-07 (rank : 109)
Query Neighborhood Hits	470	Target Neighborhood Hits	326	Shared Neighborhood Hits	236
SwissProt Accessions	O55106	Gene names	Strn
Domain Architecture
Description	Striatin.

BRWD1_HUMAN
NC score	0.666168 (rank : 122)	θ value	3.77169e-06 (rank : 124)
Query Neighborhood Hits	470	Target Neighborhood Hits	448	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRWD1_MOUSE
NC score	0.663829 (rank : 123)	θ value	3.77169e-06 (rank : 125)
Query Neighborhood Hits	470	Target Neighborhood Hits	478	Shared Neighborhood Hits	246
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

ERCC8_MOUSE
NC score	0.661773 (rank : 124)	θ value	0.000158464 (rank : 158)
Query Neighborhood Hits	470	Target Neighborhood Hits	269	Shared Neighborhood Hits	220
SwissProt Accessions	Q8CFD5, Q3U066, Q8VDC4, Q9CWK7	Gene names	Ercc8, Ckn1, Csa
Domain Architecture	No domain graphic available
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA homolog).

WDR1_HUMAN
NC score	0.660779 (rank : 125)	θ value	0.365318 (rank : 327)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	230
SwissProt Accessions	O75083, O75313, Q8N6E5, Q9UG05, Q9UG78, Q9UQE0	Gene names	WDR1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1).

STRN_HUMAN
NC score	0.660395 (rank : 126)	θ value	8.97725e-08 (rank : 101)
Query Neighborhood Hits	470	Target Neighborhood Hits	308	Shared Neighborhood Hits	230
SwissProt Accessions	O43815, Q9NP38	Gene names	STRN
Domain Architecture
Description	Striatin.

WDR26_MOUSE
NC score	0.657900 (rank : 127)	θ value	0.000121331 (rank : 157)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	231
SwissProt Accessions	Q8C6G8, Q8C4F3, Q8VDZ6	Gene names	Wdr26
Domain Architecture
Description	WD repeat protein 26.

WDR26_HUMAN
NC score	0.657649 (rank : 128)	θ value	0.000121331 (rank : 156)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	231
SwissProt Accessions	Q9H7D7, Q86UY4	Gene names	WDR26
Domain Architecture
Description	WD repeat protein 26.

ERCC8_HUMAN
NC score	0.657424 (rank : 129)	θ value	0.00509761 (rank : 211)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	220
SwissProt Accessions	Q13216, Q6FHX5, Q96GB9	Gene names	ERCC8, CKN1, CSA
Domain Architecture
Description	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA).

FAN_HUMAN
NC score	0.654438 (rank : 130)	θ value	1.9326e-10 (rank : 46)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	240
SwissProt Accessions	Q92636	Gene names	NSMAF, FAN
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

ZF106_HUMAN
NC score	0.651580 (rank : 131)	θ value	4.74913e-17 (rank : 14)
Query Neighborhood Hits	470	Target Neighborhood Hits	470	Shared Neighborhood Hits	185
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

WDR1_MOUSE
NC score	0.651553 (rank : 132)	θ value	1.38821 (rank : 386)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	230
SwissProt Accessions	O88342	Gene names	Wdr1
Domain Architecture
Description	WD repeat protein 1 (Actin-interacting protein 1) (AIP1).

RFWD2_HUMAN
NC score	0.650406 (rank : 133)	θ value	0.0330416 (rank : 254)
Query Neighborhood Hits	470	Target Neighborhood Hits	518	Shared Neighborhood Hits	367
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.650281 (rank : 134)	θ value	0.0330416 (rank : 255)
Query Neighborhood Hits	470	Target Neighborhood Hits	535	Shared Neighborhood Hits	369
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

IF32_MOUSE
NC score	0.649997 (rank : 135)	θ value	0.0961366 (rank : 277)
Query Neighborhood Hits	470	Target Neighborhood Hits	239	Shared Neighborhood Hits	212
SwissProt Accessions	Q9QZD9	Gene names	Eif3s2, Trip1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

IF32_HUMAN
NC score	0.649079 (rank : 136)	θ value	0.0961366 (rank : 276)
Query Neighborhood Hits	470	Target Neighborhood Hits	239	Shared Neighborhood Hits	212
SwissProt Accessions	Q13347	Gene names	EIF3S2, TRIP1
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) (eIF3 p36) (eIF3i) (TGF-beta receptor-interacting protein 1) (TRIP-1).

GNB1L_MOUSE
NC score	0.640625 (rank : 137)	θ value	0.0736092 (rank : 270)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	200
SwissProt Accessions	Q9EQ15, Q8R1F3, Q9CWP2, Q9D3Y1	Gene names	Gnb1l, Estm55, Wdr14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF).

ZF106_MOUSE
NC score	0.639811 (rank : 138)	θ value	1.2105e-12 (rank : 23)
Query Neighborhood Hits	470	Target Neighborhood Hits	472	Shared Neighborhood Hits	194
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

FAN_MOUSE
NC score	0.637942 (rank : 139)	θ value	3.64472e-09 (rank : 75)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	230
SwissProt Accessions	O35242	Gene names	Nsmaf, Fan
Domain Architecture
Description	Protein FAN (Factor associated with N-SMase activation) (Factor associated with neutral sphingomyelinase activation).

WDR23_MOUSE
NC score	0.632977 (rank : 140)	θ value	0.0252991 (rank : 251)
Query Neighborhood Hits	470	Target Neighborhood Hits	271	Shared Neighborhood Hits	225
SwissProt Accessions	Q91VU6, Q3U836, Q8JZV8	Gene names	Wdr23, D14Ucla1
Domain Architecture
Description	WD repeat protein 23.

WDR23_HUMAN
NC score	0.632408 (rank : 141)	θ value	0.0330416 (rank : 260)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	226
SwissProt Accessions	Q8TEB1, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3, Q9H5C9	Gene names	WDR23
Domain Architecture
Description	WD repeat protein 23.

WDR33_HUMAN
NC score	0.632100 (rank : 142)	θ value	5.44631e-05 (rank : 151)
Query Neighborhood Hits	470	Target Neighborhood Hits	638	Shared Neighborhood Hits	243
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

CAF1B_MOUSE
NC score	0.630587 (rank : 143)	θ value	0.0431538 (rank : 261)
Query Neighborhood Hits	470	Target Neighborhood Hits	385	Shared Neighborhood Hits	231
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

CAF1B_HUMAN
NC score	0.628724 (rank : 144)	θ value	0.163984 (rank : 297)
Query Neighborhood Hits	470	Target Neighborhood Hits	345	Shared Neighborhood Hits	223
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

FBXW9_HUMAN
NC score	0.626018 (rank : 145)	θ value	0.00134147 (rank : 185)
Query Neighborhood Hits	470	Target Neighborhood Hits	184	Shared Neighborhood Hits	169
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

GNB1L_HUMAN
NC score	0.619848 (rank : 146)	θ value	0.000602161 (rank : 173)
Query Neighborhood Hits	470	Target Neighborhood Hits	221	Shared Neighborhood Hits	192
SwissProt Accessions	Q9BYB4, Q9H2S2, Q9H4M4	Gene names	GNB1L, GY2, KIAA1645, WDR14
Domain Architecture
Description	Guanine nucleotide-binding protein subunit beta-like protein 1 (G protein subunit beta-like protein 1) (WD40 repeat-containing protein deleted in VCFS) (Protein WDVCF) (DGCRK3).

PWP1_MOUSE
NC score	0.613652 (rank : 147)	θ value	0.163984 (rank : 301)
Query Neighborhood Hits	470	Target Neighborhood Hits	278	Shared Neighborhood Hits	216
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

RBBP4_MOUSE
NC score	0.612133 (rank : 148)	θ value	1.09739e-05 (rank : 140)
Query Neighborhood Hits	470	Target Neighborhood Hits	289	Shared Neighborhood Hits	229
SwissProt Accessions	Q60972	Gene names	Rbbp4, Rbap48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

RBBP4_HUMAN
NC score	0.611955 (rank : 149)	θ value	1.09739e-05 (rank : 139)
Query Neighborhood Hits	470	Target Neighborhood Hits	291	Shared Neighborhood Hits	231
SwissProt Accessions	Q09028, P31149, Q53H02, Q96BV9	Gene names	RBBP4, RBAP48
Domain Architecture
Description	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).

RBBP7_HUMAN
NC score	0.610801 (rank : 150)	θ value	7.59969e-07 (rank : 110)
Query Neighborhood Hits	470	Target Neighborhood Hits	285	Shared Neighborhood Hits	231
SwissProt Accessions	Q16576	Gene names	RBBP7, RBAP46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

RBBP7_MOUSE
NC score	0.610781 (rank : 151)	θ value	7.59969e-07 (rank : 111)
Query Neighborhood Hits	470	Target Neighborhood Hits	285	Shared Neighborhood Hits	231
SwissProt Accessions	Q60973, Q3UX20	Gene names	Rbbp7, Rbap46
Domain Architecture
Description	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).

MEP50_MOUSE
NC score	0.608452 (rank : 152)	θ value	0.00665767 (rank : 216)
Query Neighborhood Hits	470	Target Neighborhood Hits	271	Shared Neighborhood Hits	218
SwissProt Accessions	Q99J09, Q3TFJ1, Q8BSH8, Q9CZY5	Gene names	Wdr77, Mep50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

FBXW4_MOUSE
NC score	0.606860 (rank : 153)	θ value	6.43352e-06 (rank : 132)
Query Neighborhood Hits	470	Target Neighborhood Hits	205	Shared Neighborhood Hits	172
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

GRWD1_HUMAN
NC score	0.605030 (rank : 154)	θ value	0.0736092 (rank : 271)
Query Neighborhood Hits	470	Target Neighborhood Hits	297	Shared Neighborhood Hits	231
SwissProt Accessions	Q9BQ67	Gene names	GRWD1, GRWD, WDR28
Domain Architecture
Description	Glutamate-rich WD repeat-containing protein 1.

GRWD1_MOUSE
NC score	0.602375 (rank : 155)	θ value	0.0736092 (rank : 272)
Query Neighborhood Hits	470	Target Neighborhood Hits	296	Shared Neighborhood Hits	229
SwissProt Accessions	Q810D6, Q922H3	Gene names	Grwd1, A301
Domain Architecture	No domain graphic available
Description	Glutamate-rich WD repeat-containing protein 1 (Protein A301).

SCAP_HUMAN
NC score	0.596715 (rank : 156)	θ value	0.00102713 (rank : 184)
Query Neighborhood Hits	470	Target Neighborhood Hits	368	Shared Neighborhood Hits	192
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

PWP1_HUMAN
NC score	0.593674 (rank : 157)	θ value	0.163984 (rank : 300)
Query Neighborhood Hits	470	Target Neighborhood Hits	261	Shared Neighborhood Hits	209
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

RAE1L_MOUSE
NC score	0.593669 (rank : 158)	θ value	0.000270298 (rank : 165)
Query Neighborhood Hits	470	Target Neighborhood Hits	225	Shared Neighborhood Hits	196
SwissProt Accessions	Q8C570, Q3UKD4	Gene names	Rae1, Mrnp41
Domain Architecture	No domain graphic available
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

WDR43_HUMAN
NC score	0.593524 (rank : 159)	θ value	0.0563607 (rank : 269)
Query Neighborhood Hits	470	Target Neighborhood Hits	269	Shared Neighborhood Hits	170
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

RAE1L_HUMAN
NC score	0.592628 (rank : 160)	θ value	0.000270298 (rank : 164)
Query Neighborhood Hits	470	Target Neighborhood Hits	222	Shared Neighborhood Hits	194
SwissProt Accessions	P78406, O15306, Q3SYL7, Q5TCH8, Q6V708, Q9H100, Q9NQM6	Gene names	RAE1, MRNP41
Domain Architecture
Description	mRNA-associated protein mrnp 41 (Rae1 protein homolog).

WDR65_HUMAN
NC score	0.591097 (rank : 161)	θ value	0.0961366 (rank : 281)
Query Neighborhood Hits	470	Target Neighborhood Hits	238	Shared Neighborhood Hits	200
SwissProt Accessions	Q96MR6, Q5TAI0	Gene names	WDR65
Domain Architecture	No domain graphic available
Description	WD repeat protein 65.

MEP50_HUMAN
NC score	0.588440 (rank : 162)	θ value	0.813845 (rank : 354)
Query Neighborhood Hits	470	Target Neighborhood Hits	268	Shared Neighborhood Hits	212
SwissProt Accessions	Q9BQA1, Q96GK4, Q9BWY3	Gene names	WDR77, MEP50
Domain Architecture
Description	Methylosome protein 50 (MEP50 protein) (WD repeat protein 77).

WDR49_HUMAN
NC score	0.585364 (rank : 163)	θ value	4.03905 (rank : 419)
Query Neighborhood Hits	470	Target Neighborhood Hits	214	Shared Neighborhood Hits	181
SwissProt Accessions	Q8IV35, Q8N297	Gene names	WDR49
Domain Architecture	No domain graphic available
Description	WD repeat protein 49.

FBXW4_HUMAN
NC score	0.583523 (rank : 164)	θ value	3.19293e-05 (rank : 145)
Query Neighborhood Hits	470	Target Neighborhood Hits	209	Shared Neighborhood Hits	174
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

BUB3_HUMAN
NC score	0.571371 (rank : 165)	θ value	0.00035302 (rank : 170)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	183
SwissProt Accessions	O43684, O43685	Gene names	BUB3
Domain Architecture
Description	Mitotic checkpoint protein BUB3.

TLE2_MOUSE
NC score	0.570707 (rank : 166)	θ value	2.21117e-06 (rank : 119)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	227
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

TLE2_HUMAN
NC score	0.569700 (rank : 167)	θ value	4.92598e-06 (rank : 130)
Query Neighborhood Hits	470	Target Neighborhood Hits	321	Shared Neighborhood Hits	229
SwissProt Accessions	Q04725, Q8WVY0, Q9Y6S0	Gene names	TLE2
Domain Architecture
Description	Transducin-like enhancer protein 2 (ESG2).

WDHD1_MOUSE
NC score	0.568541 (rank : 168)	θ value	0.000270298 (rank : 169)
Query Neighborhood Hits	470	Target Neighborhood Hits	414	Shared Neighborhood Hits	215
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

WDHD1_HUMAN
NC score	0.567319 (rank : 169)	θ value	3.19293e-05 (rank : 147)
Query Neighborhood Hits	470	Target Neighborhood Hits	342	Shared Neighborhood Hits	193
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

NEDD1_HUMAN
NC score	0.565494 (rank : 170)	θ value	0.00665767 (rank : 217)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	213
SwissProt Accessions	Q8NHV4, Q8NA30	Gene names	NEDD1
Domain Architecture	No domain graphic available
Description	Protein NEDD1.

WDFY1_HUMAN
NC score	0.563963 (rank : 171)	θ value	0.000158464 (rank : 159)
Query Neighborhood Hits	470	Target Neighborhood Hits	305	Shared Neighborhood Hits	222
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

TLE3_MOUSE
NC score	0.560319 (rank : 172)	θ value	2.88788e-06 (rank : 123)
Query Neighborhood Hits	470	Target Neighborhood Hits	378	Shared Neighborhood Hits	229
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

HIRA_MOUSE
NC score	0.560105 (rank : 173)	θ value	0.125558 (rank : 288)
Query Neighborhood Hits	470	Target Neighborhood Hits	274	Shared Neighborhood Hits	204
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

TBL2_HUMAN
NC score	0.559483 (rank : 174)	θ value	8.99809 (rank : 467)
Query Neighborhood Hits	470	Target Neighborhood Hits	225	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y4P3, Q9UQE2	Gene names	TBL2, WBSCR13
Domain Architecture
Description	Transducin beta-like 2 protein (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosome region 13 protein).

THOC6_HUMAN
NC score	0.557768 (rank : 175)	θ value	0.163984 (rank : 302)
Query Neighborhood Hits	470	Target Neighborhood Hits	223	Shared Neighborhood Hits	204
SwissProt Accessions	Q86W42, Q8NBR1, Q9BTV9	Gene names	THOC6, WDR58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

TLE3_HUMAN
NC score	0.557749 (rank : 176)	θ value	2.88788e-06 (rank : 122)
Query Neighborhood Hits	470	Target Neighborhood Hits	385	Shared Neighborhood Hits	228
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

BUB3_MOUSE
NC score	0.557426 (rank : 177)	θ value	0.000786445 (rank : 176)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	182
SwissProt Accessions	Q9WVA3, P97397	Gene names	Bub3
Domain Architecture
Description	Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5).

TLE4_HUMAN
NC score	0.557065 (rank : 178)	θ value	3.77169e-06 (rank : 127)
Query Neighborhood Hits	470	Target Neighborhood Hits	477	Shared Neighborhood Hits	230
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

NEDD1_MOUSE
NC score	0.557027 (rank : 179)	θ value	0.62314 (rank : 346)
Query Neighborhood Hits	470	Target Neighborhood Hits	281	Shared Neighborhood Hits	208
SwissProt Accessions	P33215, Q6NXV3, Q8BN12, Q8BN86, Q8BQL9, Q9CWK2	Gene names	Nedd1, Nedd-1
Domain Architecture	No domain graphic available
Description	Protein NEDD1 (Neural precursor cell expressed developmentally down- regulated protein 1).

TLE4_MOUSE
NC score	0.556872 (rank : 180)	θ value	3.77169e-06 (rank : 128)
Query Neighborhood Hits	470	Target Neighborhood Hits	482	Shared Neighborhood Hits	230
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

HIRA_HUMAN
NC score	0.556773 (rank : 181)	θ value	0.125558 (rank : 287)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	203
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

WDR24_MOUSE
NC score	0.556213 (rank : 182)	θ value	0.0431538 (rank : 265)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	202
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

TBL2_MOUSE
NC score	0.553555 (rank : 183)	θ value	0.62314 (rank : 350)
Query Neighborhood Hits	470	Target Neighborhood Hits	221	Shared Neighborhood Hits	189
SwissProt Accessions	Q9R099	Gene names	Tbl2
Domain Architecture
Description	Transducin beta-like 2 protein.

GEMI5_HUMAN
NC score	0.548500 (rank : 184)	θ value	0.00102713 (rank : 182)
Query Neighborhood Hits	470	Target Neighborhood Hits	362	Shared Neighborhood Hits	228
SwissProt Accessions	Q8TEQ6, Q8WWV4, Q969W4, Q9H9K3, Q9UFI5	Gene names	GEMIN5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

GEMI5_MOUSE
NC score	0.547818 (rank : 185)	θ value	0.00390308 (rank : 203)
Query Neighborhood Hits	470	Target Neighborhood Hits	424	Shared Neighborhood Hits	221
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

WDR55_HUMAN
NC score	0.546396 (rank : 186)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	188
SwissProt Accessions	Q9H6Y2	Gene names	WDR55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

WDR53_HUMAN
NC score	0.546064 (rank : 187)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	470	Target Neighborhood Hits	251	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z5U6	Gene names	WDR53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WDR53_MOUSE
NC score	0.545794 (rank : 188)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	470	Target Neighborhood Hits	254	Shared Neighborhood Hits	209
SwissProt Accessions	Q9DB94	Gene names	Wdr53
Domain Architecture	No domain graphic available
Description	WD repeat protein 53.

WDR79_MOUSE
NC score	0.545688 (rank : 189)	θ value	0.125558 (rank : 296)
Query Neighborhood Hits	470	Target Neighborhood Hits	216	Shared Neighborhood Hits	180
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

TLE1_HUMAN
NC score	0.545354 (rank : 190)	θ value	1.09739e-05 (rank : 141)
Query Neighborhood Hits	470	Target Neighborhood Hits	485	Shared Neighborhood Hits	228
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TLE1_MOUSE
NC score	0.545036 (rank : 191)	θ value	1.09739e-05 (rank : 142)
Query Neighborhood Hits	470	Target Neighborhood Hits	491	Shared Neighborhood Hits	228
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

STTP1_MOUSE
NC score	0.540133 (rank : 192)	θ value	0.0252991 (rank : 247)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	215
SwissProt Accessions	Q91WG4, Q3TIH5, Q3TIT0, Q8CBW6, Q9ESY7	Gene names	Statip1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1).

WDFY2_HUMAN
NC score	0.539957 (rank : 193)	θ value	0.000270298 (rank : 168)
Query Neighborhood Hits	470	Target Neighborhood Hits	332	Shared Neighborhood Hits	224
SwissProt Accessions	Q96P53, Q96CS1	Gene names	WDFY2, WDF2, ZFYVE22
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2) (Zinc finger FYVE domain-containing protein 22).

WDR55_MOUSE
NC score	0.539595 (rank : 194)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	470	Target Neighborhood Hits	236	Shared Neighborhood Hits	190
SwissProt Accessions	Q9CX97	Gene names	Wdr55
Domain Architecture	No domain graphic available
Description	WD repeat protein 55.

IF122_HUMAN
NC score	0.538725 (rank : 195)	θ value	8.99809 (rank : 456)
Query Neighborhood Hits	470	Target Neighborhood Hits	244	Shared Neighborhood Hits	209
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

WDTC1_MOUSE
NC score	0.531787 (rank : 196)	θ value	0.00869519 (rank : 228)
Query Neighborhood Hits	470	Target Neighborhood Hits	298	Shared Neighborhood Hits	218
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDTC1_HUMAN
NC score	0.531775 (rank : 197)	θ value	0.00869519 (rank : 227)
Query Neighborhood Hits	470	Target Neighborhood Hits	299	Shared Neighborhood Hits	218
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDFY2_MOUSE
NC score	0.531720 (rank : 198)	θ value	0.000786445 (rank : 179)
Query Neighborhood Hits	470	Target Neighborhood Hits	337	Shared Neighborhood Hits	224
SwissProt Accessions	Q8BUB4	Gene names	Wdfy2
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 2 (WD40- and FYVE domain- containing protein 2).

BOP1_MOUSE
NC score	0.531410 (rank : 199)	θ value	0.0330416 (rank : 253)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	214
SwissProt Accessions	P97452, Q3TK87, Q91X31	Gene names	Bop1
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

RBBP5_HUMAN
NC score	0.524125 (rank : 200)	θ value	0.365318 (rank : 324)
Query Neighborhood Hits	470	Target Neighborhood Hits	372	Shared Neighborhood Hits	181
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

STTP1_HUMAN
NC score	0.521177 (rank : 201)	θ value	0.0113563 (rank : 230)
Query Neighborhood Hits	470	Target Neighborhood Hits	232	Shared Neighborhood Hits	200
SwissProt Accessions	Q6IA86, Q53GZ0, Q687Y8, Q8N5C2, Q96GV4, Q96PI7, Q9H9N0, Q9NV81	Gene names	STATIP1
Domain Architecture	No domain graphic available
Description	Stat3-interacting protein (StIP1) (SHINC-2).

THOC6_MOUSE
NC score	0.518654 (rank : 202)	θ value	0.47712 (rank : 336)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	182
SwissProt Accessions	Q5U4D9	Gene names	Thoc6, Wdr58
Domain Architecture	No domain graphic available
Description	THO complex subunit 6 homolog (WD repeat protein 58).

EMAL2_HUMAN
NC score	0.514720 (rank : 203)	θ value	0.000270298 (rank : 163)
Query Neighborhood Hits	470	Target Neighborhood Hits	217	Shared Neighborhood Hits	185
SwissProt Accessions	O95834, Q9UG50	Gene names	EML2, EMAP2, EMAPL2
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 2 (EMAP-2) (HuEMAP-2).

WDR22_MOUSE
NC score	0.508022 (rank : 204)	θ value	0.813845 (rank : 363)
Query Neighborhood Hits	470	Target Neighborhood Hits	302	Shared Neighborhood Hits	197
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

WDR41_MOUSE
NC score	0.506158 (rank : 205)	θ value	0.47712 (rank : 340)
Query Neighborhood Hits	470	Target Neighborhood Hits	209	Shared Neighborhood Hits	179
SwissProt Accessions	Q3UDP0, Q8C4F1, Q8C8K5	Gene names	Wdr41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

WDR22_HUMAN
NC score	0.505397 (rank : 206)	θ value	0.813845 (rank : 362)
Query Neighborhood Hits	470	Target Neighborhood Hits	328	Shared Neighborhood Hits	198
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

SEC13_MOUSE
NC score	0.500899 (rank : 207)	θ value	0.0431538 (rank : 263)
Query Neighborhood Hits	470	Target Neighborhood Hits	195	Shared Neighborhood Hits	163
SwissProt Accessions	Q9D1M0, Q99M12, Q9D712	Gene names	Sec13l1
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

WDR6_HUMAN
NC score	0.499780 (rank : 208)	θ value	0.0961366 (rank : 282)
Query Neighborhood Hits	470	Target Neighborhood Hits	193	Shared Neighborhood Hits	165
SwissProt Accessions	Q9NNW5, Q9UF63	Gene names	WDR6
Domain Architecture
Description	WD repeat protein 6.

WDR79_HUMAN
NC score	0.499033 (rank : 209)	θ value	1.06291 (rank : 372)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	177
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

EMAL4_HUMAN
NC score	0.497637 (rank : 210)	θ value	0.00665767 (rank : 215)
Query Neighborhood Hits	470	Target Neighborhood Hits	306	Shared Neighborhood Hits	196
SwissProt Accessions	Q9HC35	Gene names	EML4, C2orf2, EMAPL4
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 4 (EMAP-4) (Restrictedly overexpressed proliferation-associated protein) (Ropp 120).

CORO7_MOUSE
NC score	0.497396 (rank : 211)	θ value	0.125558 (rank : 286)
Query Neighborhood Hits	470	Target Neighborhood Hits	312	Shared Neighborhood Hits	237
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

SEC13_HUMAN
NC score	0.497234 (rank : 212)	θ value	0.0431538 (rank : 262)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	166
SwissProt Accessions	P55735, Q9BRM6, Q9BUG7	Gene names	SEC13L1, SEC13R
Domain Architecture	No domain graphic available
Description	SEC13-related protein (SEC13-like protein 1).

AHI1_MOUSE
NC score	0.484118 (rank : 213)	θ value	0.125558 (rank : 284)
Query Neighborhood Hits	470	Target Neighborhood Hits	496	Shared Neighborhood Hits	216
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

BOP1_HUMAN
NC score	0.483501 (rank : 214)	θ value	0.62314 (rank : 341)
Query Neighborhood Hits	470	Target Neighborhood Hits	257	Shared Neighborhood Hits	203
SwissProt Accessions	Q14137, Q969Z6, Q96IS8, Q9BSA7, Q9BVM0	Gene names	BOP1, KIAA0124
Domain Architecture
Description	Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein).

WDR41_HUMAN
NC score	0.479704 (rank : 215)	θ value	0.47712 (rank : 339)
Query Neighborhood Hits	470	Target Neighborhood Hits	208	Shared Neighborhood Hits	184
SwissProt Accessions	Q9HAD4, Q7Z792, Q8IWG3, Q8IXA9, Q8NDA7, Q9NV62	Gene names	WDR41
Domain Architecture	No domain graphic available
Description	WD repeat protein 41.

CORO7_HUMAN
NC score	0.469275 (rank : 216)	θ value	5.27518 (rank : 426)
Query Neighborhood Hits	470	Target Neighborhood Hits	315	Shared Neighborhood Hits	231
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

EMAL1_HUMAN
NC score	0.461217 (rank : 217)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	470	Target Neighborhood Hits	214	Shared Neighborhood Hits	183
SwissProt Accessions	O00423	Gene names	EML1, EMAP1, EMAPL, EMAPL1
Domain Architecture
Description	Echinoderm microtubule-associated protein-like 1 (EMAP-1) (HuEMAP-1).

WDR81_MOUSE
NC score	0.458070 (rank : 218)	θ value	0.00869519 (rank : 226)
Query Neighborhood Hits	470	Target Neighborhood Hits	228	Shared Neighborhood Hits	178
SwissProt Accessions	Q5ND34, Q3TA90, Q3TUS9, Q6KAR1	Gene names	Wdr81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

TLE6_MOUSE
NC score	0.453894 (rank : 219)	θ value	0.000270298 (rank : 166)
Query Neighborhood Hits	470	Target Neighborhood Hits	178	Shared Neighborhood Hits	142
SwissProt Accessions	Q9WVB3	Gene names	Tle6, Grg6
Domain Architecture
Description	Transducin-like enhancer protein 6 (Groucho-related protein 6).

AHI1_HUMAN
NC score	0.453180 (rank : 220)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	470	Target Neighborhood Hits	537	Shared Neighborhood Hits	212
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

WDR75_HUMAN
NC score	0.449194 (rank : 221)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	470	Target Neighborhood Hits	193	Shared Neighborhood Hits	158
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

WDR13_HUMAN
NC score	0.433815 (rank : 222)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	470	Target Neighborhood Hits	186	Shared Neighborhood Hits	166
SwissProt Accessions	Q9H1Z4, Q9BUL7, Q9NWW4	Gene names	WDR13
Domain Architecture
Description	WD repeat protein 13.

WDR24_HUMAN
NC score	0.432745 (rank : 223)	θ value	0.0431538 (rank : 264)
Query Neighborhood Hits	470	Target Neighborhood Hits	247	Shared Neighborhood Hits	180
SwissProt Accessions	Q96S15, Q96GC7, Q9H0B7	Gene names	WDR24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WD21C_HUMAN
NC score	0.425276 (rank : 224)	θ value	1.38821 (rank : 385)
Query Neighborhood Hits	470	Target Neighborhood Hits	157	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

WDR13_MOUSE
NC score	0.420203 (rank : 225)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	470	Target Neighborhood Hits	195	Shared Neighborhood Hits	170
SwissProt Accessions	Q91V09	Gene names	Wdr13
Domain Architecture
Description	WD repeat protein 13.

SEH1L_HUMAN
NC score	0.416583 (rank : 226)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	470	Target Neighborhood Hits	145	Shared Neighborhood Hits	125
SwissProt Accessions	Q96EE3, Q8NFU6, Q96MH3, Q9C069	Gene names	SEH1L, SEC13L, SEH1
Domain Architecture
Description	Nucleoporin SEH1-like (SEC13-like protein).

WDR7_MOUSE
NC score	0.411803 (rank : 227)	θ value	0.365318 (rank : 328)
Query Neighborhood Hits	470	Target Neighborhood Hits	226	Shared Neighborhood Hits	187
SwissProt Accessions	Q920I9, Q80TY3, Q920J0	Gene names	Wdr7, Kiaa0541, Trag
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG).

WDR81_HUMAN
NC score	0.407275 (rank : 228)	θ value	0.0736092 (rank : 275)
Query Neighborhood Hits	470	Target Neighborhood Hits	205	Shared Neighborhood Hits	164
SwissProt Accessions	Q562E7, Q24JP6, Q8N277, Q8N3F3	Gene names	WDR81
Domain Architecture	No domain graphic available
Description	WD repeat protein 81.

WDR7_HUMAN
NC score	0.399809 (rank : 229)	θ value	4.03905 (rank : 420)
Query Neighborhood Hits	470	Target Neighborhood Hits	244	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y4E6, Q86UX5, Q86VP2, Q96PS7	Gene names	WDR7, KIAA0541, TRAG
Domain Architecture	No domain graphic available
Description	WD repeat protein 7 (TGF-beta resistance-associated protein TRAG) (Rabconnectin-3 beta).

CIR1A_HUMAN
NC score	0.397827 (rank : 230)	θ value	0.00102713 (rank : 181)
Query Neighborhood Hits	470	Target Neighborhood Hits	158	Shared Neighborhood Hits	129
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

DMWD_MOUSE
NC score	0.397272 (rank : 231)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	175
SwissProt Accessions	Q08274	Gene names	Dmwd, Dm9
Domain Architecture
Description	Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (DMR-N9 protein).

WDR20_MOUSE
NC score	0.395994 (rank : 232)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	470	Target Neighborhood Hits	217	Shared Neighborhood Hits	175
SwissProt Accessions	Q9D5R2	Gene names	Wdr20
Domain Architecture
Description	WD repeat protein 20.

COR2B_HUMAN
NC score	0.392699 (rank : 233)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	470	Target Neighborhood Hits	233	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UQ03, O94767, Q8TAN1	Gene names	CORO2B, KIAA0925
Domain Architecture
Description	Coronin-2B (Coronin-like protein C) (ClipinC) (Protein FC96).

CORO6_MOUSE
NC score	0.391070 (rank : 234)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	186
SwissProt Accessions	Q920M5, Q920M3, Q920M4	Gene names	Coro6
Domain Architecture	No domain graphic available
Description	Coronin-6 (Clipin E).

COR2B_MOUSE
NC score	0.390088 (rank : 235)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	470	Target Neighborhood Hits	235	Shared Neighborhood Hits	194
SwissProt Accessions	Q8BH44, Q6P5U9	Gene names	Coro2b
Domain Architecture	No domain graphic available
Description	Coronin-2B.

KI21B_HUMAN
NC score	0.389999 (rank : 236)	θ value	1.86753e-13 (rank : 20)
Query Neighborhood Hits	470	Target Neighborhood Hits	1017	Shared Neighborhood Hits	252
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

DMXL2_HUMAN
NC score	0.389046 (rank : 237)	θ value	0.21417 (rank : 313)
Query Neighborhood Hits	470	Target Neighborhood Hits	374	Shared Neighborhood Hits	203
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

COR1A_MOUSE
NC score	0.387716 (rank : 238)	θ value	0.62314 (rank : 342)
Query Neighborhood Hits	470	Target Neighborhood Hits	243	Shared Neighborhood Hits	193
SwissProt Accessions	O89053, Q7TMU0, Q9R1Y8, Q9R288	Gene names	Coro1a, Coro1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

KI21B_MOUSE
NC score	0.380975 (rank : 239)	θ value	1.02475e-11 (rank : 30)
Query Neighborhood Hits	470	Target Neighborhood Hits	997	Shared Neighborhood Hits	254
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

WDR20_HUMAN
NC score	0.380863 (rank : 240)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	470	Target Neighborhood Hits	249	Shared Neighborhood Hits	177
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

CIR1A_MOUSE
NC score	0.380181 (rank : 241)	θ value	0.000461057 (rank : 172)
Query Neighborhood Hits	470	Target Neighborhood Hits	155	Shared Neighborhood Hits	122
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

COR1A_HUMAN
NC score	0.380054 (rank : 242)	θ value	0.21417 (rank : 312)
Query Neighborhood Hits	470	Target Neighborhood Hits	240	Shared Neighborhood Hits	188
SwissProt Accessions	P31146	Gene names	CORO1A, CORO1
Domain Architecture
Description	Coronin-1A (Coronin-like protein p57) (Coronin-like protein A) (CLIPINA) (Tryptophan aspartate-containing coat protein) (TACO).

NUP43_MOUSE
NC score	0.377804 (rank : 243)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	470	Target Neighborhood Hits	193	Shared Neighborhood Hits	160
SwissProt Accessions	P59235	Gene names	Nup43
Domain Architecture
Description	Nucleoporin Nup43.

COR1C_HUMAN
NC score	0.376285 (rank : 244)	θ value	4.03905 (rank : 408)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	186
SwissProt Accessions	Q9ULV4, Q9NSK5	Gene names	CORO1C, CRNN4
Domain Architecture
Description	Coronin-1C (Coronin-3) (hCRNN4).

COR1C_MOUSE
NC score	0.374298 (rank : 245)	θ value	4.03905 (rank : 409)
Query Neighborhood Hits	470	Target Neighborhood Hits	251	Shared Neighborhood Hits	187
SwissProt Accessions	Q9WUM4, Q8VCQ5	Gene names	Coro1c
Domain Architecture
Description	Coronin-1C (Coronin-3).

NUP43_HUMAN
NC score	0.374126 (rank : 246)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	470	Target Neighborhood Hits	198	Shared Neighborhood Hits	164
SwissProt Accessions	Q8NFH3, Q9H8S0	Gene names	NUP43
Domain Architecture
Description	Nucleoporin Nup43 (p42).

NUP37_MOUSE
NC score	0.370505 (rank : 247)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	470	Target Neighborhood Hits	159	Shared Neighborhood Hits	140
SwissProt Accessions	Q9CWU9	Gene names	Nup37
Domain Architecture
Description	Nucleoporin Nup37.

KI21A_HUMAN
NC score	0.368758 (rank : 248)	θ value	4.44505e-15 (rank : 18)
Query Neighborhood Hits	470	Target Neighborhood Hits	1543	Shared Neighborhood Hits	278
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

WDFY3_HUMAN
NC score	0.365321 (rank : 249)	θ value	0.000786445 (rank : 180)
Query Neighborhood Hits	470	Target Neighborhood Hits	348	Shared Neighborhood Hits	195
SwissProt Accessions	Q8IZQ1, Q4W5K5, Q6P0Q5, Q8N1T2, Q96BS7, Q96N85, Q9Y2J7	Gene names	WDFY3, KIAA0993
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy).

WDFY3_MOUSE
NC score	0.364389 (rank : 250)	θ value	0.00175202 (rank : 192)
Query Neighborhood Hits	470	Target Neighborhood Hits	332	Shared Neighborhood Hits	199
SwissProt Accessions	Q6VNB8, Q8C8H7	Gene names	Wdfy3
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 3 (Beach domain, WD repeat and FYVE domain-containing protein 1) (BWF1).

KI21A_MOUSE
NC score	0.364149 (rank : 251)	θ value	2.69671e-12 (rank : 25)
Query Neighborhood Hits	470	Target Neighborhood Hits	1317	Shared Neighborhood Hits	256
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

COR1B_HUMAN
NC score	0.362857 (rank : 252)	θ value	0.0193708 (rank : 239)
Query Neighborhood Hits	470	Target Neighborhood Hits	239	Shared Neighborhood Hits	182
SwissProt Accessions	Q9BR76	Gene names	CORO1B
Domain Architecture
Description	Coronin-1B (Coronin-2).

COR1B_MOUSE
NC score	0.359808 (rank : 253)	θ value	0.0193708 (rank : 240)
Query Neighborhood Hits	470	Target Neighborhood Hits	235	Shared Neighborhood Hits	176
SwissProt Accessions	Q9WUM3, Q3UEB1, Q9CVA2	Gene names	Coro1b
Domain Architecture
Description	Coronin-1B (Coronin-2).

IFT80_MOUSE
NC score	0.359484 (rank : 254)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	154
SwissProt Accessions	Q8K057	Gene names	Ift80, Wdr56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

NUP37_HUMAN
NC score	0.352421 (rank : 255)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	470	Target Neighborhood Hits	153	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NFH4, Q9H644	Gene names	NUP37
Domain Architecture
Description	Nucleoporin Nup37 (p37).

IFT80_HUMAN
NC score	0.349721 (rank : 256)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	470	Target Neighborhood Hits	195	Shared Neighborhood Hits	154
SwissProt Accessions	Q9P2H3	Gene names	IFT80, KIAA1374, WDR56
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 80 homolog (WD repeat protein 56).

DMXL1_MOUSE
NC score	0.347163 (rank : 257)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	470	Target Neighborhood Hits	257	Shared Neighborhood Hits	193
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

LYST_HUMAN
NC score	0.346911 (rank : 258)	θ value	0.47712 (rank : 330)
Query Neighborhood Hits	470	Target Neighborhood Hits	324	Shared Neighborhood Hits	168
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

LYST_MOUSE
NC score	0.341855 (rank : 259)	θ value	0.00298849 (rank : 197)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	162
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

COR2A_HUMAN
NC score	0.339702 (rank : 260)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	470	Target Neighborhood Hits	214	Shared Neighborhood Hits	165
SwissProt Accessions	Q92828, Q92829, Q9BWS5	Gene names	CORO2A, IR10, WDR2
Domain Architecture
Description	Coronin-2A (WD repeat-containing protein 2) (IR10).

DDB2_HUMAN
NC score	0.337825 (rank : 261)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	470	Target Neighborhood Hits	175	Shared Neighborhood Hits	140
SwissProt Accessions	Q92466, Q76E54, Q76E55, Q76E56, Q76E57	Gene names	DDB2
Domain Architecture
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2) (DDB p48 subunit) (DDBb) (UV-damaged DNA-binding protein 2) (UV-DDB 2).

DDB2_MOUSE
NC score	0.334946 (rank : 262)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	470	Target Neighborhood Hits	175	Shared Neighborhood Hits	145
SwissProt Accessions	Q99J79	Gene names	Ddb2
Domain Architecture	No domain graphic available
Description	DNA damage-binding protein 2 (Damage-specific DNA-binding protein 2).

COR2A_MOUSE
NC score	0.329895 (rank : 263)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	470	Target Neighborhood Hits	204	Shared Neighborhood Hits	154
SwissProt Accessions	Q8C0P5, Q3U6H8, Q8BW42	Gene names	Coro2a
Domain Architecture	No domain graphic available
Description	Coronin-2A.

PREB_HUMAN
NC score	0.328945 (rank : 264)	θ value	6.88961 (rank : 449)
Query Neighborhood Hits	470	Target Neighborhood Hits	163	Shared Neighborhood Hits	142
SwissProt Accessions	Q9HCU5, Q9UH94	Gene names	PREB, SEC12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

TLE6_HUMAN
NC score	0.328546 (rank : 265)	θ value	0.00390308 (rank : 207)
Query Neighborhood Hits	470	Target Neighborhood Hits	120	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H808	Gene names	TLE6
Domain Architecture	No domain graphic available
Description	Transducin-like enhancer protein 6.

FBXW8_HUMAN
NC score	0.321490 (rank : 266)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	470	Target Neighborhood Hits	192	Shared Neighborhood Hits	128
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

TSCC1_MOUSE
NC score	0.320214 (rank : 267)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	470	Target Neighborhood Hits	160	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K0G5	Gene names	Tssc1
Domain Architecture	No domain graphic available
Description	Protein TSSC1.

WD21A_HUMAN
NC score	0.319792 (rank : 268)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	470	Target Neighborhood Hits	136	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WV16, Q86U31, Q96K22, Q9Y4P5	Gene names	WDR21A, WDR21
Domain Architecture
Description	WD repeat protein 21A.

WDR4_MOUSE
NC score	0.318246 (rank : 269)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	470	Target Neighborhood Hits	136	Shared Neighborhood Hits	124
SwissProt Accessions	Q9EP82	Gene names	Wdr4
Domain Architecture
Description	WD repeat protein 4.

WDR72_HUMAN
NC score	0.316860 (rank : 270)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	470	Target Neighborhood Hits	167	Shared Neighborhood Hits	134
SwissProt Accessions	Q3MJ13, Q7Z3I3, Q8N8X2	Gene names	WDR72
Domain Architecture	No domain graphic available
Description	WD repeat protein 72.

WDR4_HUMAN
NC score	0.315709 (rank : 271)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	470	Target Neighborhood Hits	145	Shared Neighborhood Hits	130
SwissProt Accessions	P57081, Q9HCR3	Gene names	WDR4
Domain Architecture
Description	WD repeat protein 4.

TRAF6_MOUSE
NC score	0.314847 (rank : 272)	θ value	1.38499e-08 (rank : 88)
Query Neighborhood Hits	470	Target Neighborhood Hits	255	Shared Neighborhood Hits	150
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

NBEAL_HUMAN
NC score	0.314616 (rank : 273)	θ value	0.62314 (rank : 345)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	157
SwissProt Accessions	Q6ZS30, Q6Y876, Q6ZQY5, Q96Q30	Gene names	NBEAL1, ALS2CR17
Domain Architecture	No domain graphic available
Description	Neurobeachin-like 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein).

TSSC1_HUMAN
NC score	0.314283 (rank : 274)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	470	Target Neighborhood Hits	157	Shared Neighborhood Hits	130
SwissProt Accessions	Q53HC9, O43179, Q53S19, Q53SG2	Gene names	TSSC1
Domain Architecture	No domain graphic available
Description	Protein TSSC1 (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) (Tumor-suppressing STF cDNA 1 protein).

TRAF6_HUMAN
NC score	0.313558 (rank : 275)	θ value	1.38499e-08 (rank : 87)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

UTP18_HUMAN
NC score	0.307381 (rank : 276)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

FBXW5_MOUSE
NC score	0.304128 (rank : 277)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	470	Target Neighborhood Hits	159	Shared Neighborhood Hits	122
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

WDR67_MOUSE
NC score	0.301023 (rank : 278)	θ value	0.62314 (rank : 352)
Query Neighborhood Hits	470	Target Neighborhood Hits	476	Shared Neighborhood Hits	141
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

DMXL1_HUMAN
NC score	0.298617 (rank : 279)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	470	Target Neighborhood Hits	259	Shared Neighborhood Hits	193
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

AAAS_HUMAN
NC score	0.297919 (rank : 280)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	470	Target Neighborhood Hits	154	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NRG9, Q9NWI6, Q9UG19	Gene names	AAAS, ADRACALA
Domain Architecture
Description	Aladin (Adracalin).

PREB_MOUSE
NC score	0.297845 (rank : 281)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	470	Target Neighborhood Hits	156	Shared Neighborhood Hits	134
SwissProt Accessions	Q9WUQ2, Q9QZ99	Gene names	Preb, Sec12
Domain Architecture
Description	Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12).

FBXW8_MOUSE
NC score	0.292137 (rank : 282)	θ value	0.62314 (rank : 344)
Query Neighborhood Hits	470	Target Neighborhood Hits	162	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BIA4, Q8BI62, Q8BI75, Q8BI76, Q8CID8, Q921Z1	Gene names	Fbxw8
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8).

TRAF5_MOUSE
NC score	0.287623 (rank : 283)	θ value	2.52405e-10 (rank : 54)
Query Neighborhood Hits	470	Target Neighborhood Hits	355	Shared Neighborhood Hits	138
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

FBXW5_HUMAN
NC score	0.287558 (rank : 284)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	470	Target Neighborhood Hits	156	Shared Neighborhood Hits	120
SwissProt Accessions	Q969U6, Q5SPZ8, Q5SPZ9, Q5SQ02, Q5SQ03, Q5SQ04, Q8WY79, Q96GJ6, Q9BSU8, Q9H6A8, Q9HBQ6, Q9NSZ3	Gene names	FBXW5, FBW5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

ZN313_MOUSE
NC score	0.282014 (rank : 285)	θ value	0.00020696 (rank : 162)
Query Neighborhood Hits	470	Target Neighborhood Hits	273	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRAF4_HUMAN
NC score	0.278539 (rank : 286)	θ value	5.08577e-11 (rank : 40)
Query Neighborhood Hits	470	Target Neighborhood Hits	373	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF5_HUMAN
NC score	0.276729 (rank : 287)	θ value	1.9326e-10 (rank : 50)
Query Neighborhood Hits	470	Target Neighborhood Hits	396	Shared Neighborhood Hits	126
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

WDR85_HUMAN
NC score	0.273604 (rank : 288)	θ value	1.38821 (rank : 387)
Query Neighborhood Hits	470	Target Neighborhood Hits	134	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BTV6, Q96AB7	Gene names	WDR85, C9orf112
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

ZN313_HUMAN
NC score	0.271406 (rank : 289)	θ value	0.00134147 (rank : 187)
Query Neighborhood Hits	470	Target Neighborhood Hits	264	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

WDR46_HUMAN
NC score	0.265243 (rank : 290)	θ value	8.99809 (rank : 469)
Query Neighborhood Hits	470	Target Neighborhood Hits	147	Shared Neighborhood Hits	105
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

RN125_HUMAN
NC score	0.261462 (rank : 291)	θ value	0.000602161 (rank : 174)
Query Neighborhood Hits	470	Target Neighborhood Hits	230	Shared Neighborhood Hits	142
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
NC score	0.258753 (rank : 292)	θ value	0.00390308 (rank : 206)
Query Neighborhood Hits	470	Target Neighborhood Hits	220	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RNF41_MOUSE
NC score	0.258053 (rank : 293)	θ value	0.00298849 (rank : 199)
Query Neighborhood Hits	470	Target Neighborhood Hits	224	Shared Neighborhood Hits	146
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.258025 (rank : 294)	θ value	0.00298849 (rank : 198)
Query Neighborhood Hits	470	Target Neighborhood Hits	226	Shared Neighborhood Hits	146
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRAF4_MOUSE
NC score	0.257259 (rank : 295)	θ value	8.67504e-11 (rank : 42)
Query Neighborhood Hits	470	Target Neighborhood Hits	338	Shared Neighborhood Hits	100
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

WDR74_HUMAN
NC score	0.253963 (rank : 296)	θ value	0.00665767 (rank : 222)
Query Neighborhood Hits	470	Target Neighborhood Hits	94	Shared Neighborhood Hits	81
SwissProt Accessions	Q6RFH5, Q9BRC9, Q9H6X8, Q9NVY2	Gene names	WDR74, NSA1
Domain Architecture	No domain graphic available
Description	WD repeat protein 74 (NOP seven-associated protein 1).

TRAF3_HUMAN
NC score	0.252174 (rank : 297)	θ value	4.30538e-10 (rank : 60)
Query Neighborhood Hits	470	Target Neighborhood Hits	463	Shared Neighborhood Hits	125
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

RN166_MOUSE
NC score	0.251872 (rank : 298)	θ value	0.0563607 (rank : 266)
Query Neighborhood Hits	470	Target Neighborhood Hits	248	Shared Neighborhood Hits	149
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

AAAS_MOUSE
NC score	0.251375 (rank : 299)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	470	Target Neighborhood Hits	144	Shared Neighborhood Hits	112
SwissProt Accessions	P58742, Q544M6	Gene names	Aaas
Domain Architecture
Description	Aladin (Adracalin).

RN166_HUMAN
NC score	0.249809 (rank : 300)	θ value	0.0736092 (rank : 273)
Query Neighborhood Hits	470	Target Neighborhood Hits	240	Shared Neighborhood Hits	146
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRAF3_MOUSE
NC score	0.248822 (rank : 301)	θ value	1.38499e-08 (rank : 86)
Query Neighborhood Hits	470	Target Neighborhood Hits	476	Shared Neighborhood Hits	129
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

WDR67_HUMAN
NC score	0.247798 (rank : 302)	θ value	0.813845 (rank : 364)
Query Neighborhood Hits	470	Target Neighborhood Hits	782	Shared Neighborhood Hits	157
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

UTP18_MOUSE
NC score	0.239211 (rank : 303)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	98
SwissProt Accessions	Q5SSI6	Gene names	Utp18, Wdr50
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

TRI52_HUMAN
NC score	0.238506 (rank : 304)	θ value	0.00134147 (rank : 186)
Query Neighborhood Hits	470	Target Neighborhood Hits	213	Shared Neighborhood Hits	141
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI13_HUMAN
NC score	0.235605 (rank : 305)	θ value	0.00175202 (rank : 188)
Query Neighborhood Hits	470	Target Neighborhood Hits	274	Shared Neighborhood Hits	151
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
NC score	0.235412 (rank : 306)	θ value	0.00175202 (rank : 189)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	153
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI59_HUMAN
NC score	0.234356 (rank : 307)	θ value	0.00175202 (rank : 190)
Query Neighborhood Hits	470	Target Neighborhood Hits	307	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
NC score	0.234295 (rank : 308)	θ value	0.00175202 (rank : 191)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	152
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

ARC1B_HUMAN
NC score	0.232509 (rank : 309)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	470	Target Neighborhood Hits	148	Shared Neighborhood Hits	123
SwissProt Accessions	O15143, Q9BU00	Gene names	ARPC1B, ARC41
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

DC1I2_MOUSE
NC score	0.231317 (rank : 310)	θ value	0.365318 (rank : 323)
Query Neighborhood Hits	470	Target Neighborhood Hits	209	Shared Neighborhood Hits	129
SwissProt Accessions	O88487, Q3TGH7	Gene names	Dync1i2, Dnci2, Dncic2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

WDR68_HUMAN
NC score	0.229228 (rank : 311)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	470	Target Neighborhood Hits	121	Shared Neighborhood Hits	106
SwissProt Accessions	P61962, O15491, Q9DAE4	Gene names	WDR68, HAN11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

WDR68_MOUSE
NC score	0.229228 (rank : 312)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	470	Target Neighborhood Hits	121	Shared Neighborhood Hits	106
SwissProt Accessions	P61963, O15491, Q3TMV9, Q9DAE4	Gene names	Wdr68, Han11
Domain Architecture
Description	WD repeat protein 68 (WD repeat protein An11 homolog).

TRI65_HUMAN
NC score	0.227951 (rank : 313)	θ value	0.0148317 (rank : 237)
Query Neighborhood Hits	470	Target Neighborhood Hits	330	Shared Neighborhood Hits	163
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

DC1I2_HUMAN
NC score	0.227646 (rank : 314)	θ value	0.365318 (rank : 322)
Query Neighborhood Hits	470	Target Neighborhood Hits	201	Shared Neighborhood Hits	127
SwissProt Accessions	Q13409, Q96NG7, Q96S87, Q9BXZ5, Q9NT58	Gene names	DYNC1I2, DNCI2, DNCIC2
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 2 (Dynein intermediate chain 2, cytosolic) (DH IC-2) (Cytoplasmic dynein intermediate chain 2).

TRI31_HUMAN
NC score	0.226319 (rank : 315)	θ value	0.21417 (rank : 315)
Query Neighborhood Hits	470	Target Neighborhood Hits	299	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

DNAI2_HUMAN
NC score	0.224407 (rank : 316)	θ value	6.88961 (rank : 444)
Query Neighborhood Hits	470	Target Neighborhood Hits	156	Shared Neighborhood Hits	110
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

WDR46_MOUSE
NC score	0.222572 (rank : 317)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	470	Target Neighborhood Hits	243	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

TRI73_HUMAN
NC score	0.221314 (rank : 318)	θ value	0.0961366 (rank : 279)
Query Neighborhood Hits	470	Target Neighborhood Hits	258	Shared Neighborhood Hits	154
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI12_MOUSE
NC score	0.217929 (rank : 319)	θ value	0.21417 (rank : 314)
Query Neighborhood Hits	470	Target Neighborhood Hits	387	Shared Neighborhood Hits	165
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI40_HUMAN
NC score	0.216994 (rank : 320)	θ value	0.62314 (rank : 351)
Query Neighborhood Hits	470	Target Neighborhood Hits	279	Shared Neighborhood Hits	159
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

PZRN3_MOUSE
NC score	0.216641 (rank : 321)	θ value	7.34386e-10 (rank : 63)
Query Neighborhood Hits	470	Target Neighborhood Hits	447	Shared Neighborhood Hits	147
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRIM4_HUMAN
NC score	0.216125 (rank : 322)	θ value	0.00298849 (rank : 202)
Query Neighborhood Hits	470	Target Neighborhood Hits	321	Shared Neighborhood Hits	163
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI74_HUMAN
NC score	0.215828 (rank : 323)	θ value	0.163984 (rank : 307)
Query Neighborhood Hits	470	Target Neighborhood Hits	249	Shared Neighborhood Hits	150
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI26_MOUSE
NC score	0.215697 (rank : 324)	θ value	0.0330416 (rank : 259)
Query Neighborhood Hits	470	Target Neighborhood Hits	339	Shared Neighborhood Hits	168
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI26_HUMAN
NC score	0.215240 (rank : 325)	θ value	0.0330416 (rank : 258)
Query Neighborhood Hits	470	Target Neighborhood Hits	335	Shared Neighborhood Hits	162
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

PZRN3_HUMAN
NC score	0.214960 (rank : 326)	θ value	2.79066e-09 (rank : 74)
Query Neighborhood Hits	470	Target Neighborhood Hits	461	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRIM8_HUMAN
NC score	0.214650 (rank : 327)	θ value	0.00665767 (rank : 221)
Query Neighborhood Hits	470	Target Neighborhood Hits	650	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ARC1B_MOUSE
NC score	0.214584 (rank : 328)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	470	Target Neighborhood Hits	133	Shared Neighborhood Hits	110
SwissProt Accessions	Q9WV32	Gene names	Arpc1b
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

NBEA_HUMAN
NC score	0.214086 (rank : 329)	θ value	1.38821 (rank : 377)
Query Neighborhood Hits	470	Target Neighborhood Hits	186	Shared Neighborhood Hits	107
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

TRI50_HUMAN
NC score	0.214081 (rank : 330)	θ value	0.00509761 (rank : 212)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	164
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI25_MOUSE
NC score	0.213917 (rank : 331)	θ value	0.00298849 (rank : 200)
Query Neighborhood Hits	470	Target Neighborhood Hits	446	Shared Neighborhood Hits	164
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI65_MOUSE
NC score	0.213883 (rank : 332)	θ value	0.0961366 (rank : 278)
Query Neighborhood Hits	470	Target Neighborhood Hits	340	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM8_MOUSE
NC score	0.213558 (rank : 333)	θ value	0.0148317 (rank : 238)
Query Neighborhood Hits	470	Target Neighborhood Hits	674	Shared Neighborhood Hits	162
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

DNAI1_HUMAN
NC score	0.213372 (rank : 334)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	470	Target Neighborhood Hits	148	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UI46, Q9UEZ8	Gene names	DNAI1
Domain Architecture
Description	Dynein intermediate chain 1, axonemal (Axonemal dynein intermediate chain 1).

NBEA_MOUSE
NC score	0.213313 (rank : 335)	θ value	1.38821 (rank : 378)
Query Neighborhood Hits	470	Target Neighborhood Hits	225	Shared Neighborhood Hits	110
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

TRI35_MOUSE
NC score	0.212195 (rank : 336)	θ value	0.0148317 (rank : 236)
Query Neighborhood Hits	470	Target Neighborhood Hits	465	Shared Neighborhood Hits	165
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

LRBA_HUMAN
NC score	0.210217 (rank : 337)	θ value	2.36792 (rank : 396)
Query Neighborhood Hits	470	Target Neighborhood Hits	196	Shared Neighborhood Hits	98
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

TRI50_MOUSE
NC score	0.209985 (rank : 338)	θ value	0.0113563 (rank : 234)
Query Neighborhood Hits	470	Target Neighborhood Hits	326	Shared Neighborhood Hits	168
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

WDR74_MOUSE
NC score	0.209734 (rank : 339)	θ value	0.0961366 (rank : 283)
Query Neighborhood Hits	470	Target Neighborhood Hits	70	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VCG3	Gene names	Wdr74
Domain Architecture	No domain graphic available
Description	WD repeat protein 74.

ZN179_HUMAN
NC score	0.209071 (rank : 340)	θ value	0.0252991 (rank : 252)
Query Neighborhood Hits	470	Target Neighborhood Hits	178	Shared Neighborhood Hits	123
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI25_HUMAN
NC score	0.208271 (rank : 341)	θ value	0.00665767 (rank : 219)
Query Neighborhood Hits	470	Target Neighborhood Hits	472	Shared Neighborhood Hits	167
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI35_HUMAN
NC score	0.208169 (rank : 342)	θ value	0.0252991 (rank : 248)
Query Neighborhood Hits	470	Target Neighborhood Hits	382	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

BRCA1_HUMAN
NC score	0.207106 (rank : 343)	θ value	0.0252991 (rank : 245)
Query Neighborhood Hits	470	Target Neighborhood Hits	381	Shared Neighborhood Hits	166
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TRAF2_MOUSE
NC score	0.206845 (rank : 344)	θ value	0.0193708 (rank : 242)
Query Neighborhood Hits	470	Target Neighborhood Hits	394	Shared Neighborhood Hits	115
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

RAG1_HUMAN
NC score	0.206403 (rank : 345)	θ value	0.00869519 (rank : 224)
Query Neighborhood Hits	470	Target Neighborhood Hits	203	Shared Neighborhood Hits	123
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

TRI17_HUMAN
NC score	0.205508 (rank : 346)	θ value	0.000270298 (rank : 167)
Query Neighborhood Hits	470	Target Neighborhood Hits	318	Shared Neighborhood Hits	162
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

BFAR_MOUSE
NC score	0.204650 (rank : 347)	θ value	0.0113563 (rank : 229)
Query Neighborhood Hits	470	Target Neighborhood Hits	232	Shared Neighborhood Hits	133
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI43_HUMAN
NC score	0.203220 (rank : 348)	θ value	0.0563607 (rank : 267)
Query Neighborhood Hits	470	Target Neighborhood Hits	341	Shared Neighborhood Hits	160
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

RAG1_MOUSE
NC score	0.201831 (rank : 349)	θ value	0.0148317 (rank : 235)
Query Neighborhood Hits	470	Target Neighborhood Hits	189	Shared Neighborhood Hits	129
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI60_HUMAN
NC score	0.201197 (rank : 350)	θ value	0.00869519 (rank : 225)
Query Neighborhood Hits	470	Target Neighborhood Hits	357	Shared Neighborhood Hits	168
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI30_MOUSE
NC score	0.200889 (rank : 351)	θ value	0.125558 (rank : 291)
Query Neighborhood Hits	470	Target Neighborhood Hits	434	Shared Neighborhood Hits	166
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI48_HUMAN
NC score	0.200458 (rank : 352)	θ value	0.0113563 (rank : 233)
Query Neighborhood Hits	470	Target Neighborhood Hits	192	Shared Neighborhood Hits	132
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

BRCA1_MOUSE
NC score	0.200325 (rank : 353)	θ value	0.0252991 (rank : 246)
Query Neighborhood Hits	470	Target Neighborhood Hits	436	Shared Neighborhood Hits	168
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BFAR_HUMAN
NC score	0.200207 (rank : 354)	θ value	0.125558 (rank : 285)
Query Neighborhood Hits	470	Target Neighborhood Hits	222	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRI10_HUMAN
NC score	0.199807 (rank : 355)	θ value	0.163984 (rank : 303)
Query Neighborhood Hits	470	Target Neighborhood Hits	315	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI11_HUMAN
NC score	0.199704 (rank : 356)	θ value	0.00228821 (rank : 194)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	160
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

R113B_HUMAN
NC score	0.199559 (rank : 357)	θ value	0.00228821 (rank : 193)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TRI11_MOUSE
NC score	0.199379 (rank : 358)	θ value	0.00228821 (rank : 195)
Query Neighborhood Hits	470	Target Neighborhood Hits	329	Shared Neighborhood Hits	161
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI62_MOUSE
NC score	0.198523 (rank : 359)	θ value	0.00509761 (rank : 214)
Query Neighborhood Hits	470	Target Neighborhood Hits	478	Shared Neighborhood Hits	164
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RPTOR_HUMAN
NC score	0.198107 (rank : 360)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	470	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N122, Q8N4V9, Q8TB32, Q9P2P3	Gene names	RAPTOR, KIAA1303
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

TRIM7_MOUSE
NC score	0.197672 (rank : 361)	θ value	0.00390308 (rank : 209)
Query Neighborhood Hits	470	Target Neighborhood Hits	358	Shared Neighborhood Hits	154
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI22_HUMAN
NC score	0.196896 (rank : 362)	θ value	1.06291 (rank : 365)
Query Neighborhood Hits	470	Target Neighborhood Hits	396	Shared Neighborhood Hits	164
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRIM7_HUMAN
NC score	0.196502 (rank : 363)	θ value	0.00665767 (rank : 220)
Query Neighborhood Hits	470	Target Neighborhood Hits	336	Shared Neighborhood Hits	155
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI10_MOUSE
NC score	0.196420 (rank : 364)	θ value	0.163984 (rank : 304)
Query Neighborhood Hits	470	Target Neighborhood Hits	285	Shared Neighborhood Hits	155
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI68_MOUSE
NC score	0.196142 (rank : 365)	θ value	0.00390308 (rank : 208)
Query Neighborhood Hits	470	Target Neighborhood Hits	356	Shared Neighborhood Hits	158
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI49_HUMAN
NC score	0.196054 (rank : 366)	θ value	0.00298849 (rank : 201)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI62_HUMAN
NC score	0.195920 (rank : 367)	θ value	0.00509761 (rank : 213)
Query Neighborhood Hits	470	Target Neighborhood Hits	584	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

PZRN4_HUMAN
NC score	0.195047 (rank : 368)	θ value	9.92553e-07 (rank : 114)
Query Neighborhood Hits	470	Target Neighborhood Hits	438	Shared Neighborhood Hits	145
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRIM5_HUMAN
NC score	0.193507 (rank : 369)	θ value	0.813845 (rank : 361)
Query Neighborhood Hits	470	Target Neighborhood Hits	424	Shared Neighborhood Hits	171
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI39_MOUSE
NC score	0.193081 (rank : 370)	θ value	0.0113563 (rank : 232)
Query Neighborhood Hits	470	Target Neighborhood Hits	691	Shared Neighborhood Hits	188
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRAF2_HUMAN
NC score	0.192803 (rank : 371)	θ value	0.365318 (rank : 326)
Query Neighborhood Hits	470	Target Neighborhood Hits	402	Shared Neighborhood Hits	112
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRI17_MOUSE
NC score	0.192745 (rank : 372)	θ value	0.000786445 (rank : 178)
Query Neighborhood Hits	470	Target Neighborhood Hits	620	Shared Neighborhood Hits	165
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

DC1I1_HUMAN
NC score	0.192406 (rank : 373)	θ value	0.163984 (rank : 298)
Query Neighborhood Hits	470	Target Neighborhood Hits	183	Shared Neighborhood Hits	106
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

R113A_HUMAN
NC score	0.191973 (rank : 374)	θ value	0.0193708 (rank : 241)
Query Neighborhood Hits	470	Target Neighborhood Hits	177	Shared Neighborhood Hits	119
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TRI39_HUMAN
NC score	0.191410 (rank : 375)	θ value	0.0113563 (rank : 231)
Query Neighborhood Hits	470	Target Neighborhood Hits	693	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RO52_HUMAN
NC score	0.191397 (rank : 376)	θ value	0.0330416 (rank : 257)
Query Neighborhood Hits	470	Target Neighborhood Hits	419	Shared Neighborhood Hits	179
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI60_MOUSE
NC score	0.191021 (rank : 377)	θ value	0.163984 (rank : 305)
Query Neighborhood Hits	470	Target Neighborhood Hits	240	Shared Neighborhood Hits	145
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI68_HUMAN
NC score	0.190062 (rank : 378)	θ value	0.163984 (rank : 306)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	149
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

PEX10_HUMAN
NC score	0.189823 (rank : 379)	θ value	2.36792 (rank : 399)
Query Neighborhood Hits	470	Target Neighborhood Hits	255	Shared Neighborhood Hits	145
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

DC1I1_MOUSE
NC score	0.189567 (rank : 380)	θ value	0.163984 (rank : 299)
Query Neighborhood Hits	470	Target Neighborhood Hits	206	Shared Neighborhood Hits	109
SwissProt Accessions	O88485, O88486	Gene names	Dync1i1, Dnci1, Dncic1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

SIAH2_HUMAN
NC score	0.188928 (rank : 381)	θ value	7.59969e-07 (rank : 112)
Query Neighborhood Hits	470	Target Neighborhood Hits	94	Shared Neighborhood Hits	53
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
NC score	0.188633 (rank : 382)	θ value	7.59969e-07 (rank : 113)
Query Neighborhood Hits	470	Target Neighborhood Hits	101	Shared Neighborhood Hits	53
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

TRI47_MOUSE
NC score	0.187711 (rank : 383)	θ value	1.38821 (rank : 382)
Query Neighborhood Hits	470	Target Neighborhood Hits	295	Shared Neighborhood Hits	147
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM6_HUMAN
NC score	0.186408 (rank : 384)	θ value	1.06291 (rank : 371)
Query Neighborhood Hits	470	Target Neighborhood Hits	412	Shared Neighborhood Hits	154
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

WDR85_MOUSE
NC score	0.186005 (rank : 385)	θ value	8.99809 (rank : 470)
Query Neighborhood Hits	470	Target Neighborhood Hits	108	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CYU6, Q5RJV7, Q8BIT9	Gene names	Wdr85
Domain Architecture	No domain graphic available
Description	WD repeat protein 85.

RO52_MOUSE
NC score	0.185770 (rank : 386)	θ value	1.81305 (rank : 394)
Query Neighborhood Hits	470	Target Neighborhood Hits	360	Shared Neighborhood Hits	166
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI47_HUMAN
NC score	0.185614 (rank : 387)	θ value	1.38821 (rank : 381)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	146
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI34_HUMAN
NC score	0.184968 (rank : 388)	θ value	0.47712 (rank : 337)
Query Neighborhood Hits	470	Target Neighborhood Hits	416	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

RN168_HUMAN
NC score	0.184892 (rank : 389)	θ value	0.365318 (rank : 325)
Query Neighborhood Hits	470	Target Neighborhood Hits	370	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI41_HUMAN
NC score	0.184524 (rank : 390)	θ value	0.0252991 (rank : 249)
Query Neighborhood Hits	470	Target Neighborhood Hits	349	Shared Neighborhood Hits	140
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

RNF39_HUMAN
NC score	0.184024 (rank : 391)	θ value	0.0330416 (rank : 256)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	129
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRIM6_MOUSE
NC score	0.183153 (rank : 392)	θ value	1.38821 (rank : 384)
Query Neighborhood Hits	470	Target Neighborhood Hits	451	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI38_HUMAN
NC score	0.182994 (rank : 393)	θ value	0.47712 (rank : 338)
Query Neighborhood Hits	470	Target Neighborhood Hits	373	Shared Neighborhood Hits	155
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI15_HUMAN
NC score	0.181251 (rank : 394)	θ value	0.0736092 (rank : 274)
Query Neighborhood Hits	470	Target Neighborhood Hits	395	Shared Neighborhood Hits	151
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

RPTOR_MOUSE
NC score	0.180038 (rank : 395)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	470	Target Neighborhood Hits	129	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

ARC1A_HUMAN
NC score	0.176755 (rank : 396)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	470	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	Q92747, Q7Z5U8, Q86WU5, Q8IXQ0	Gene names	ARPC1A, SOP2L
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein).

ARC1A_MOUSE
NC score	0.176716 (rank : 397)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	470	Target Neighborhood Hits	120	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0Q6, Q3UL75	Gene names	Arpc1a, Sid329
Domain Architecture	No domain graphic available
Description	Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329).

BRWD2_HUMAN
NC score	0.175951 (rank : 398)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	470	Target Neighborhood Hits	94	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BZH6, Q5VWA1	Gene names	BRWD2, WDR11
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 2 (WD repeat protein 11).

TRI63_MOUSE
NC score	0.175113 (rank : 399)	θ value	0.0563607 (rank : 268)
Query Neighborhood Hits	470	Target Neighborhood Hits	240	Shared Neighborhood Hits	118
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRIM3_MOUSE
NC score	0.172839 (rank : 400)	θ value	0.0193708 (rank : 243)
Query Neighborhood Hits	470	Target Neighborhood Hits	351	Shared Neighborhood Hits	151
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.172141 (rank : 401)	θ value	0.0252991 (rank : 250)
Query Neighborhood Hits	470	Target Neighborhood Hits	357	Shared Neighborhood Hits	151
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI63_HUMAN
NC score	0.171119 (rank : 402)	θ value	0.125558 (rank : 292)
Query Neighborhood Hits	470	Target Neighborhood Hits	298	Shared Neighborhood Hits	124
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI32_HUMAN
NC score	0.170862 (rank : 403)	θ value	1.06291 (rank : 366)
Query Neighborhood Hits	470	Target Neighborhood Hits	264	Shared Neighborhood Hits	132
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI55_HUMAN
NC score	0.170545 (rank : 404)	θ value	1.38821 (rank : 383)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

RN185_HUMAN
NC score	0.170307 (rank : 405)	θ value	0.47712 (rank : 334)
Query Neighborhood Hits	470	Target Neighborhood Hits	213	Shared Neighborhood Hits	134
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRIM2_HUMAN
NC score	0.170167 (rank : 406)	θ value	0.0961366 (rank : 280)
Query Neighborhood Hits	470	Target Neighborhood Hits	330	Shared Neighborhood Hits	152
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.170163 (rank : 407)	θ value	0.125558 (rank : 293)
Query Neighborhood Hits	470	Target Neighborhood Hits	331	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

RN185_MOUSE
NC score	0.169937 (rank : 408)	θ value	0.47712 (rank : 335)
Query Neighborhood Hits	470	Target Neighborhood Hits	211	Shared Neighborhood Hits	134
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI32_MOUSE
NC score	0.169686 (rank : 409)	θ value	0.813845 (rank : 360)
Query Neighborhood Hits	470	Target Neighborhood Hits	271	Shared Neighborhood Hits	134
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI54_HUMAN
NC score	0.169596 (rank : 410)	θ value	1.06291 (rank : 369)
Query Neighborhood Hits	470	Target Neighborhood Hits	209	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

RN168_MOUSE
NC score	0.169577 (rank : 411)	θ value	1.81305 (rank : 392)
Query Neighborhood Hits	470	Target Neighborhood Hits	440	Shared Neighborhood Hits	162
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI54_MOUSE
NC score	0.169223 (rank : 412)	θ value	1.06291 (rank : 370)
Query Neighborhood Hits	470	Target Neighborhood Hits	197	Shared Neighborhood Hits	116
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

PI3R4_HUMAN
NC score	0.168246 (rank : 413)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	470	Target Neighborhood Hits	534	Shared Neighborhood Hits	134
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

TRI27_HUMAN
NC score	0.167385 (rank : 414)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	470	Target Neighborhood Hits	273	Shared Neighborhood Hits	153
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
NC score	0.167342 (rank : 415)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	470	Target Neighborhood Hits	261	Shared Neighborhood Hits	153
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

SIAH1_HUMAN
NC score	0.165266 (rank : 416)	θ value	0.00020696 (rank : 161)
Query Neighborhood Hits	470	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

TRI18_MOUSE
NC score	0.164785 (rank : 417)	θ value	0.125558 (rank : 290)
Query Neighborhood Hits	470	Target Neighborhood Hits	292	Shared Neighborhood Hits	138
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI34_MOUSE
NC score	0.164682 (rank : 418)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	470	Target Neighborhood Hits	332	Shared Neighborhood Hits	135
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

SIA1B_MOUSE
NC score	0.163087 (rank : 419)	θ value	0.00020696 (rank : 160)
Query Neighborhood Hits	470	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

TRI18_HUMAN
NC score	0.162994 (rank : 420)	θ value	0.125558 (rank : 289)
Query Neighborhood Hits	470	Target Neighborhood Hits	307	Shared Neighborhood Hits	138
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRIM1_HUMAN
NC score	0.161614 (rank : 421)	θ value	0.163984 (rank : 308)
Query Neighborhood Hits	470	Target Neighborhood Hits	345	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

SIA1A_MOUSE
NC score	0.160727 (rank : 422)	θ value	0.000602161 (rank : 175)
Query Neighborhood Hits	470	Target Neighborhood Hits	72	Shared Neighborhood Hits	40
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

TRIM1_MOUSE
NC score	0.160279 (rank : 423)	θ value	0.163984 (rank : 309)
Query Neighborhood Hits	470	Target Neighborhood Hits	361	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

LNX1_HUMAN
NC score	0.159974 (rank : 424)	θ value	0.00035302 (rank : 171)
Query Neighborhood Hits	470	Target Neighborhood Hits	379	Shared Neighborhood Hits	149
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
NC score	0.159863 (rank : 425)	θ value	0.00102713 (rank : 183)
Query Neighborhood Hits	470	Target Neighborhood Hits	377	Shared Neighborhood Hits	146
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRIM9_MOUSE
NC score	0.157986 (rank : 426)	θ value	0.125558 (rank : 295)
Query Neighborhood Hits	470	Target Neighborhood Hits	274	Shared Neighborhood Hits	122
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRIM9_HUMAN
NC score	0.156160 (rank : 427)	θ value	0.125558 (rank : 294)
Query Neighborhood Hits	470	Target Neighborhood Hits	294	Shared Neighborhood Hits	123
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

WDR54_MOUSE
NC score	0.156115 (rank : 428)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	470	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R0D8, Q3U4A4	Gene names	Wdr54, D3Mm3e
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

PI3R4_MOUSE
NC score	0.155375 (rank : 429)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	470	Target Neighborhood Hits	535	Shared Neighborhood Hits	127
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

LNX2_MOUSE
NC score	0.153043 (rank : 430)	θ value	0.00390308 (rank : 205)
Query Neighborhood Hits	470	Target Neighborhood Hits	407	Shared Neighborhood Hits	151
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX2_HUMAN
NC score	0.152563 (rank : 431)	θ value	0.00390308 (rank : 204)
Query Neighborhood Hits	470	Target Neighborhood Hits	389	Shared Neighborhood Hits	148
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RNF5_HUMAN
NC score	0.152092 (rank : 432)	θ value	3.0926 (rank : 405)
Query Neighborhood Hits	470	Target Neighborhood Hits	206	Shared Neighborhood Hits	130
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF8_MOUSE
NC score	0.151109 (rank : 433)	θ value	6.88961 (rank : 452)
Query Neighborhood Hits	470	Target Neighborhood Hits	618	Shared Neighborhood Hits	178
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRAF1_MOUSE
NC score	0.150452 (rank : 434)	θ value	0.813845 (rank : 359)
Query Neighborhood Hits	470	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

RNF5_MOUSE
NC score	0.150144 (rank : 435)	θ value	3.0926 (rank : 406)
Query Neighborhood Hits	470	Target Neighborhood Hits	206	Shared Neighborhood Hits	128
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF4_HUMAN
NC score	0.148079 (rank : 436)	θ value	6.88961 (rank : 450)
Query Neighborhood Hits	470	Target Neighborhood Hits	212	Shared Neighborhood Hits	131
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.147090 (rank : 437)	θ value	6.88961 (rank : 451)
Query Neighborhood Hits	470	Target Neighborhood Hits	212	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

WDR8_HUMAN
NC score	0.144708 (rank : 438)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	470	Target Neighborhood Hits	69	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P2S5, Q5T0D6, Q9BUH7, Q9NTK7, Q9NX56	Gene names	WDR8
Domain Architecture
Description	WD repeat protein 8.

RNF8_HUMAN
NC score	0.142935 (rank : 439)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	470	Target Neighborhood Hits	622	Shared Neighborhood Hits	176
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI46_MOUSE
NC score	0.142496 (rank : 440)	θ value	1.06291 (rank : 368)
Query Neighborhood Hits	470	Target Neighborhood Hits	287	Shared Neighborhood Hits	125
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI56_HUMAN
NC score	0.142240 (rank : 441)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	470	Target Neighborhood Hits	339	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI46_HUMAN
NC score	0.142143 (rank : 442)	θ value	1.06291 (rank : 367)
Query Neighborhood Hits	470	Target Neighborhood Hits	291	Shared Neighborhood Hits	127
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RING1_HUMAN
NC score	0.141677 (rank : 443)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	470	Target Neighborhood Hits	219	Shared Neighborhood Hits	128
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

TRI56_MOUSE
NC score	0.140829 (rank : 444)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	470	Target Neighborhood Hits	255	Shared Neighborhood Hits	142
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRAF1_HUMAN
NC score	0.139611 (rank : 445)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	470	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

RING1_MOUSE
NC score	0.139563 (rank : 446)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	470	Target Neighborhood Hits	220	Shared Neighborhood Hits	129
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

PCGF6_HUMAN
NC score	0.138539 (rank : 447)	θ value	0.00665767 (rank : 218)
Query Neighborhood Hits	470	Target Neighborhood Hits	178	Shared Neighborhood Hits	94
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
NC score	0.137959 (rank : 448)	θ value	0.00869519 (rank : 223)
Query Neighborhood Hits	470	Target Neighborhood Hits	163	Shared Neighborhood Hits	93
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PPWD1_HUMAN
NC score	0.137818 (rank : 449)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	470	Target Neighborhood Hits	136	Shared Neighborhood Hits	94
SwissProt Accessions	Q96BP3, Q15002, Q7KZ89	Gene names	PPWD1, KIAA0073
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

WDR34_MOUSE
NC score	0.136007 (rank : 450)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	470	Target Neighborhood Hits	105	Shared Neighborhood Hits	79
SwissProt Accessions	Q5U4F6	Gene names	Wdr34
Domain Architecture	No domain graphic available
Description	WD repeat protein 34.

PPWD1_MOUSE
NC score	0.133058 (rank : 451)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

WDR8_MOUSE
NC score	0.132564 (rank : 452)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	470	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JM98	Gene names	Wdr8, Dd57
Domain Architecture
Description	WD repeat protein 8.

RING2_MOUSE
NC score	0.131188 (rank : 453)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	123
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.131137 (rank : 454)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	470	Target Neighborhood Hits	201	Shared Neighborhood Hits	123
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

TRI36_HUMAN
NC score	0.127266 (rank : 455)	θ value	4.03905 (rank : 418)
Query Neighborhood Hits	470	Target Neighborhood Hits	282	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

CHFR_HUMAN
NC score	0.127061 (rank : 456)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	470	Target Neighborhood Hits	255	Shared Neighborhood Hits	131
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
NC score	0.126171 (rank : 457)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	470	Target Neighborhood Hits	264	Shared Neighborhood Hits	134
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

WDR34_HUMAN
NC score	0.126145 (rank : 458)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	470	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	Q96EX3, Q5VXV4, Q9BV46	Gene names	WDR34
Domain Architecture
Description	WD repeat protein 34.

MEFV_HUMAN
NC score	0.125476 (rank : 459)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	470	Target Neighborhood Hits	431	Shared Neighborhood Hits	88
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI36_MOUSE
NC score	0.125208 (rank : 460)	θ value	5.27518 (rank : 436)
Query Neighborhood Hits	470	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI37_MOUSE
NC score	0.122970 (rank : 461)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	128
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI37_HUMAN
NC score	0.122725 (rank : 462)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	470	Target Neighborhood Hits	307	Shared Neighborhood Hits	128
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

RFPL3_HUMAN
NC score	0.121246 (rank : 463)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	470	Target Neighborhood Hits	134	Shared Neighborhood Hits	94
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

TRI14_MOUSE
NC score	0.121067 (rank : 464)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	470	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

RFPL2_HUMAN
NC score	0.120797 (rank : 465)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	470	Target Neighborhood Hits	126	Shared Neighborhood Hits	92
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRI14_HUMAN
NC score	0.119345 (rank : 466)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	470	Target Neighborhood Hits	143	Shared Neighborhood Hits	74
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

WDR35_HUMAN
NC score	0.118224 (rank : 467)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	470	Target Neighborhood Hits	132	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P2L0, Q8NE11	Gene names	WDR35, KIAA1336
Domain Architecture
Description	WD repeat protein 35.

RFPL1_HUMAN
NC score	0.117251 (rank : 468)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	470	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

UHRF2_HUMAN
NC score	0.115643 (rank : 469)	θ value	2.36792 (rank : 403)
Query Neighborhood Hits	470	Target Neighborhood Hits	269	Shared Neighborhood Hits	138
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.115161 (rank : 470)	θ value	2.36792 (rank : 404)
Query Neighborhood Hits	470	Target Neighborhood Hits	275	Shared Neighborhood Hits	138
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

MEFV_MOUSE
NC score	0.114280 (rank : 471)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	470	Target Neighborhood Hits	236	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

AES_MOUSE
NC score	0.113549 (rank : 472)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	470	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	P63002, Q06195	Gene names	Aes, Esp1, Grg
Domain Architecture	No domain graphic available
Description	Amino-terminal enhancer of split (Amino enhancer of split) (GRG protein) (Protein ESP1) (Grg-5).

AES_HUMAN
NC score	0.113483 (rank : 473)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	470	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q08117, Q12808, Q96TG9, Q9UDY9	Gene names	AES, GRG
Domain Architecture
Description	Amino-terminal enhancer of split (Amino enhancer of split) (GRG protein) (Protein ESP1) (Gp130-associated protein GAM).

SMRA3_HUMAN
NC score	0.110520 (rank : 474)	θ value	0.62314 (rank : 349)
Query Neighborhood Hits	470	Target Neighborhood Hits	265	Shared Neighborhood Hits	138
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

BSPRY_MOUSE
NC score	0.109828 (rank : 475)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	470	Target Neighborhood Hits	163	Shared Neighborhood Hits	65
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI16_HUMAN
NC score	0.108290 (rank : 476)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	76
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI44_MOUSE
NC score	0.108147 (rank : 477)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	470	Target Neighborhood Hits	327	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

STB5L_MOUSE
NC score	0.108085 (rank : 478)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	470	Target Neighborhood Hits	138	Shared Neighborhood Hits	94
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

SMRA3_MOUSE
NC score	0.107873 (rank : 479)	θ value	0.813845 (rank : 358)
Query Neighborhood Hits	470	Target Neighborhood Hits	267	Shared Neighborhood Hits	144
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

STB5L_HUMAN
NC score	0.107508 (rank : 480)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

ERMAP_HUMAN
NC score	0.107381 (rank : 481)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	470	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI16_MOUSE
NC score	0.107085 (rank : 482)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	470	Target Neighborhood Hits	196	Shared Neighborhood Hits	71
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_MOUSE
NC score	0.106744 (rank : 483)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	470	Target Neighborhood Hits	306	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

RN146_HUMAN
NC score	0.105649 (rank : 484)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	470	Target Neighborhood Hits	162	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RAD18_MOUSE
NC score	0.105645 (rank : 485)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	470	Target Neighborhood Hits	230	Shared Neighborhood Hits	117
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

STXB5_HUMAN
NC score	0.105562 (rank : 486)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	470	Target Neighborhood Hits	167	Shared Neighborhood Hits	107
SwissProt Accessions	Q5T5C0, Q5T5C1, Q5T5C2, Q8NBG8, Q96NG9	Gene names	STXBP5, LLGL3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

TRI44_HUMAN
NC score	0.105281 (rank : 487)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	470	Target Neighborhood Hits	393	Shared Neighborhood Hits	78
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

BSPRY_HUMAN
NC score	0.104629 (rank : 488)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	470	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RN146_MOUSE
NC score	0.104593 (rank : 489)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	470	Target Neighborhood Hits	161	Shared Neighborhood Hits	106
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN169_HUMAN
NC score	0.104198 (rank : 490)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	470	Target Neighborhood Hits	203	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TRI29_HUMAN
NC score	0.104116 (rank : 491)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	470	Target Neighborhood Hits	273	Shared Neighborhood Hits	80
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

BIRC7_HUMAN
NC score	0.103772 (rank : 492)	θ value	1.81305 (rank : 388)
Query Neighborhood Hits	470	Target Neighborhood Hits	185	Shared Neighborhood Hits	123
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

RC3H1_MOUSE
NC score	0.101974 (rank : 493)	θ value	0.279714 (rank : 317)
Query Neighborhood Hits	470	Target Neighborhood Hits	244	Shared Neighborhood Hits	104
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

WDR35_MOUSE
NC score	0.101970 (rank : 494)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	470	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

WDR54_HUMAN
NC score	0.101279 (rank : 495)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	470	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H977, Q53H85, Q86V45	Gene names	WDR54
Domain Architecture	No domain graphic available
Description	WD repeat protein 54.

TF3C2_MOUSE
NC score	0.099170 (rank : 496)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

RAD18_HUMAN
NC score	0.098944 (rank : 497)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	470	Target Neighborhood Hits	284	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

ERMAP_MOUSE
NC score	0.097895 (rank : 498)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

IF140_HUMAN
NC score	0.096734 (rank : 499)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	470	Target Neighborhood Hits	111	Shared Neighborhood Hits	60
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

CM007_MOUSE
NC score	0.096638 (rank : 500)	θ value	6.88961 (rank : 442)
Query Neighborhood Hits	470	Target Neighborhood Hits	416	Shared Neighborhood Hits	118
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TR95_MOUSE
NC score	0.096628 (rank : 501)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	470	Target Neighborhood Hits	95	Shared Neighborhood Hits	78
SwissProt Accessions	Q6PGF3	Gene names	Thrap5
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) (Thyroid hormone receptor-associated protein 5) (Vitamin D3 receptor-interacting protein complex component DRIP92).

RC3H1_HUMAN
NC score	0.096048 (rank : 502)	θ value	0.279714 (rank : 316)
Query Neighborhood Hits	470	Target Neighborhood Hits	433	Shared Neighborhood Hits	105
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

SPRY4_MOUSE
NC score	0.095839 (rank : 503)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	470	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BT1A1_MOUSE
NC score	0.094958 (rank : 504)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	470	Target Neighborhood Hits	252	Shared Neighborhood Hits	54
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

STXB5_MOUSE
NC score	0.093973 (rank : 505)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	470	Target Neighborhood Hits	161	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K400, Q80TM5, Q8K401, Q9D2F3	Gene names	Stxbp5, Kiaa4253, Llgl3
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5 (Tomosyn-1) (Lethal(2) giant larvae protein homolog 3).

BT2A2_HUMAN
NC score	0.093444 (rank : 506)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	470	Target Neighborhood Hits	191	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT3A3_HUMAN
NC score	0.093320 (rank : 507)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	470	Target Neighborhood Hits	233	Shared Neighborhood Hits	54
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT1A1_HUMAN
NC score	0.092778 (rank : 508)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	470	Target Neighborhood Hits	322	Shared Neighborhood Hits	54
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A1_HUMAN
NC score	0.092408 (rank : 509)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	470	Target Neighborhood Hits	229	Shared Neighborhood Hits	54
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

RN183_HUMAN
NC score	0.092321 (rank : 510)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	470	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

SPRY4_HUMAN
NC score	0.092156 (rank : 511)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	470	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

BTNL9_HUMAN
NC score	0.091123 (rank : 512)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	470	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BTNL3_HUMAN
NC score	0.090649 (rank : 513)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	470	Target Neighborhood Hits	143	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

RN141_MOUSE
NC score	0.090484 (rank : 514)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	470	Target Neighborhood Hits	200	Shared Neighborhood Hits	116
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.090382 (rank : 515)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	470	Target Neighborhood Hits	199	Shared Neighborhood Hits	116
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

BT2A3_HUMAN
NC score	0.089731 (rank : 516)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	470	Target Neighborhood Hits	195	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT2A1_HUMAN
NC score	0.089640 (rank : 517)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	470	Target Neighborhood Hits	185	Shared Neighborhood Hits	53
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

TRI42_HUMAN
NC score	0.089316 (rank : 518)	θ value	5.27518 (rank : 437)
Query Neighborhood Hits	470	Target Neighborhood Hits	283	Shared Neighborhood Hits	92
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

DTX3_MOUSE
NC score	0.088601 (rank : 519)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	470	Target Neighborhood Hits	202	Shared Neighborhood Hits	111
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TRI45_HUMAN
NC score	0.088522 (rank : 520)	θ value	3.0926 (rank : 407)
Query Neighborhood Hits	470	Target Neighborhood Hits	155	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

DTX3_HUMAN
NC score	0.088051 (rank : 521)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	470	Target Neighborhood Hits	198	Shared Neighborhood Hits	109
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

TRI42_MOUSE
NC score	0.086895 (rank : 522)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	470	Target Neighborhood Hits	316	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

BTNL8_HUMAN
NC score	0.086524 (rank : 523)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	470	Target Neighborhood Hits	177	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

UHRF1_HUMAN
NC score	0.086426 (rank : 524)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	470	Target Neighborhood Hits	272	Shared Neighborhood Hits	131
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
NC score	0.085923 (rank : 525)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	470	Target Neighborhood Hits	278	Shared Neighborhood Hits	134
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

TF3C2_HUMAN
NC score	0.085280 (rank : 526)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	470	Target Neighborhood Hits	168	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

MNAB_HUMAN
NC score	0.083607 (rank : 527)	θ value	0.47712 (rank : 331)
Query Neighborhood Hits	470	Target Neighborhood Hits	196	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
NC score	0.082910 (rank : 528)	θ value	0.47712 (rank : 332)
Query Neighborhood Hits	470	Target Neighborhood Hits	231	Shared Neighborhood Hits	86
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RN183_MOUSE
NC score	0.082444 (rank : 529)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	470	Target Neighborhood Hits	119	Shared Neighborhood Hits	80
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

FBX16_HUMAN
NC score	0.081888 (rank : 530)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	470	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

CM007_HUMAN
NC score	0.079411 (rank : 531)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	470	Target Neighborhood Hits	422	Shared Neighborhood Hits	119
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

WDR19_HUMAN
NC score	0.079137 (rank : 532)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	470	Target Neighborhood Hits	88	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEZ3, Q8N5B4, Q9H5S0, Q9HCD4	Gene names	WDR19, KIAA1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

TULP4_MOUSE
NC score	0.079030 (rank : 533)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	470	Target Neighborhood Hits	247	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

PML_MOUSE
NC score	0.078372 (rank : 534)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	470	Target Neighborhood Hits	246	Shared Neighborhood Hits	105
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI45_MOUSE
NC score	0.077821 (rank : 535)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	470	Target Neighborhood Hits	155	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

PCGF4_MOUSE
NC score	0.077330 (rank : 536)	θ value	8.99809 (rank : 464)
Query Neighborhood Hits	470	Target Neighborhood Hits	163	Shared Neighborhood Hits	89
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.077175 (rank : 537)	θ value	8.99809 (rank : 463)
Query Neighborhood Hits	470	Target Neighborhood Hits	161	Shared Neighborhood Hits	90
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

WDR19_MOUSE
NC score	0.076972 (rank : 538)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	470	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q3UGF1, Q6ZPK8, Q80VQ6, Q8C794, Q8K3R5	Gene names	Wdr19, Kiaa1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

PCGF2_HUMAN
NC score	0.076881 (rank : 539)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	470	Target Neighborhood Hits	222	Shared Neighborhood Hits	93
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.076507 (rank : 540)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	470	Target Neighborhood Hits	213	Shared Neighborhood Hits	91
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

FBX16_MOUSE
NC score	0.074701 (rank : 541)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	470	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QZM9, Q3TP74, Q8C5V6	Gene names	Fbxo16, Fbx16
Domain Architecture
Description	F-box only protein 16.

WIPI1_MOUSE
NC score	0.073863 (rank : 542)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	470	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R3E3, Q8BGE1, Q8R1A9, Q8R1C7	Gene names	Wipi1, D11Ertd498e
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa).

WDR76_HUMAN
NC score	0.072874 (rank : 543)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	470	Target Neighborhood Hits	73	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H967	Gene names	WDR76
Domain Architecture	No domain graphic available
Description	WD repeat protein 76.

PML_HUMAN
NC score	0.072181 (rank : 544)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	470	Target Neighborhood Hits	248	Shared Neighborhood Hits	94
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PDZK4_HUMAN
NC score	0.070453 (rank : 545)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

CBL_HUMAN
NC score	0.070301 (rank : 546)	θ value	5.27518 (rank : 424)
Query Neighborhood Hits	470	Target Neighborhood Hits	353	Shared Neighborhood Hits	123
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

PDZK4_MOUSE
NC score	0.070219 (rank : 547)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

CBLC_HUMAN
NC score	0.069632 (rank : 548)	θ value	6.88961 (rank : 440)
Query Neighborhood Hits	470	Target Neighborhood Hits	173	Shared Neighborhood Hits	102
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

TOPRS_MOUSE
NC score	0.068652 (rank : 549)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	470	Target Neighborhood Hits	263	Shared Neighborhood Hits	101
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CBLC_MOUSE
NC score	0.068547 (rank : 550)	θ value	6.88961 (rank : 441)
Query Neighborhood Hits	470	Target Neighborhood Hits	186	Shared Neighborhood Hits	104
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_MOUSE
NC score	0.068485 (rank : 551)	θ value	5.27518 (rank : 425)
Query Neighborhood Hits	470	Target Neighborhood Hits	426	Shared Neighborhood Hits	126
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TIF1G_HUMAN
NC score	0.067653 (rank : 552)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	470	Target Neighborhood Hits	410	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

CBLB_MOUSE
NC score	0.067559 (rank : 553)	θ value	5.27518 (rank : 423)
Query Neighborhood Hits	470	Target Neighborhood Hits	277	Shared Neighborhood Hits	116
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

TULP4_HUMAN
NC score	0.067353 (rank : 554)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	470	Target Neighborhood Hits	426	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

AMFR2_HUMAN
NC score	0.067000 (rank : 555)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	470	Target Neighborhood Hits	219	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

CBLB_HUMAN
NC score	0.066367 (rank : 556)	θ value	5.27518 (rank : 422)
Query Neighborhood Hits	470	Target Neighborhood Hits	261	Shared Neighborhood Hits	113
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

TIF1G_MOUSE
NC score	0.065694 (rank : 557)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	470	Target Neighborhood Hits	498	Shared Neighborhood Hits	88
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

AMFR_MOUSE
NC score	0.065603 (rank : 558)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	470	Target Neighborhood Hits	208	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TOPRS_HUMAN
NC score	0.065140 (rank : 559)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	470	Target Neighborhood Hits	286	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

BRE1B_MOUSE
NC score	0.064685 (rank : 560)	θ value	0.21417 (rank : 311)
Query Neighborhood Hits	470	Target Neighborhood Hits	970	Shared Neighborhood Hits	147
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

RNF34_MOUSE
NC score	0.064611 (rank : 561)	θ value	2.36792 (rank : 402)
Query Neighborhood Hits	470	Target Neighborhood Hits	160	Shared Neighborhood Hits	76
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.064402 (rank : 562)	θ value	2.36792 (rank : 401)
Query Neighborhood Hits	470	Target Neighborhood Hits	153	Shared Neighborhood Hits	76
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

BRE1B_HUMAN
NC score	0.062836 (rank : 563)	θ value	0.21417 (rank : 310)
Query Neighborhood Hits	470	Target Neighborhood Hits	1040	Shared Neighborhood Hits	149
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

WIPI1_HUMAN
NC score	0.061914 (rank : 564)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	470	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q5MNZ9, Q8IXM5, Q9NWF8	Gene names	WIPI1, WIPI49
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa) (Atg18 protein homolog).

PEX12_MOUSE
NC score	0.060191 (rank : 565)	θ value	0.62314 (rank : 348)
Query Neighborhood Hits	470	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VC48	Gene names	Pex12
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12).

NHLC1_MOUSE
NC score	0.059682 (rank : 566)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	470	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

WIPI2_HUMAN
NC score	0.059201 (rank : 567)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	470	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y4P8, Q5MNZ8, Q6FI96, Q75L50, Q96IE4, Q9Y364	Gene names	WIPI2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2).

RN152_MOUSE
NC score	0.058356 (rank : 568)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	470	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

PEX12_HUMAN
NC score	0.058080 (rank : 569)	θ value	0.62314 (rank : 347)
Query Neighborhood Hits	470	Target Neighborhood Hits	32	Shared Neighborhood Hits	21
SwissProt Accessions	O00623	Gene names	PEX12, PAF3
Domain Architecture
Description	Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3).

MGRN1_HUMAN
NC score	0.058035 (rank : 570)	θ value	2.36792 (rank : 397)
Query Neighborhood Hits	470	Target Neighborhood Hits	192	Shared Neighborhood Hits	79
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

NOL10_MOUSE
NC score	0.058031 (rank : 571)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	470	Target Neighborhood Hits	206	Shared Neighborhood Hits	54
SwissProt Accessions	Q5RJG1	Gene names	Nol10, Gm67
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

RBBP6_MOUSE
NC score	0.057855 (rank : 572)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	470	Target Neighborhood Hits	1014	Shared Neighborhood Hits	130
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

BRE1A_MOUSE
NC score	0.057802 (rank : 573)	θ value	0.365318 (rank : 321)
Query Neighborhood Hits	470	Target Neighborhood Hits	1025	Shared Neighborhood Hits	141
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1A_HUMAN
NC score	0.057248 (rank : 574)	θ value	0.365318 (rank : 320)
Query Neighborhood Hits	470	Target Neighborhood Hits	1071	Shared Neighborhood Hits	141
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

RN152_HUMAN
NC score	0.055907 (rank : 575)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	470	Target Neighborhood Hits	107	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

NOL10_HUMAN
NC score	0.054562 (rank : 576)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	470	Target Neighborhood Hits	254	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

NHLC1_HUMAN
NC score	0.053763 (rank : 577)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	470	Target Neighborhood Hits	91	Shared Neighborhood Hits	57
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

WIPI2_MOUSE
NC score	0.053154 (rank : 578)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	470	Target Neighborhood Hits	55	Shared Neighborhood Hits	38
SwissProt Accessions	Q80W47	Gene names	Wipi2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2).

WIPI3_MOUSE
NC score	0.052670 (rank : 579)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	470	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CR39, Q3U924	Gene names	Wdr45l, Wipi3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein).

WIPI3_HUMAN
NC score	0.052239 (rank : 580)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	470	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5MNZ6, O95328, Q6IBN2	Gene names	WDR45L, WIPI3
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat protein 45-like) (WDR45-like protein) (WIPI49-like protein).

PJA1_HUMAN
NC score	0.052197 (rank : 581)	θ value	1.38821 (rank : 379)
Query Neighborhood Hits	470	Target Neighborhood Hits	159	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

TIF1B_HUMAN
NC score	0.052145 (rank : 582)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	470	Target Neighborhood Hits	312	Shared Neighborhood Hits	81
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.051133 (rank : 583)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	470	Target Neighborhood Hits	276	Shared Neighborhood Hits	80
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

PJA1_MOUSE
NC score	0.049056 (rank : 584)	θ value	1.38821 (rank : 380)
Query Neighborhood Hits	470	Target Neighborhood Hits	145	Shared Neighborhood Hits	45
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

NEUL1_HUMAN
NC score	0.048931 (rank : 585)	θ value	5.27518 (rank : 433)
Query Neighborhood Hits	470	Target Neighborhood Hits	114	Shared Neighborhood Hits	60
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

BIRC8_HUMAN
NC score	0.048241 (rank : 586)	θ value	1.38821 (rank : 373)
Query Neighborhood Hits	470	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

NEURL_MOUSE
NC score	0.048124 (rank : 587)	θ value	5.27518 (rank : 434)
Query Neighborhood Hits	470	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

MKRN1_HUMAN
NC score	0.045641 (rank : 588)	θ value	1.81305 (rank : 391)
Query Neighborhood Hits	470	Target Neighborhood Hits	141	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN4_HUMAN
NC score	0.045130 (rank : 589)	θ value	6.88961 (rank : 448)
Query Neighborhood Hits	470	Target Neighborhood Hits	147	Shared Neighborhood Hits	69
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

RFFL_HUMAN
NC score	0.042782 (rank : 590)	θ value	8.99809 (rank : 465)
Query Neighborhood Hits	470	Target Neighborhood Hits	175	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
NC score	0.042471 (rank : 591)	θ value	8.99809 (rank : 466)
Query Neighborhood Hits	470	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

MKRN1_MOUSE
NC score	0.040626 (rank : 592)	θ value	4.03905 (rank : 413)
Query Neighborhood Hits	470	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

KIF3A_HUMAN
NC score	0.039295 (rank : 593)	θ value	8.99809 (rank : 457)
Query Neighborhood Hits	470	Target Neighborhood Hits	704	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_MOUSE
NC score	0.039149 (rank : 594)	θ value	8.99809 (rank : 458)
Query Neighborhood Hits	470	Target Neighborhood Hits	715	Shared Neighborhood Hits	47
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MKRN3_HUMAN
NC score	0.039021 (rank : 595)	θ value	8.99809 (rank : 461)
Query Neighborhood Hits	470	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN3_MOUSE
NC score	0.038995 (rank : 596)	θ value	2.36792 (rank : 398)
Query Neighborhood Hits	470	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MYLIP_HUMAN
NC score	0.033064 (rank : 597)	θ value	0.47712 (rank : 333)
Query Neighborhood Hits	470	Target Neighborhood Hits	162	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

SMC3_HUMAN
NC score	0.030273 (rank : 598)	θ value	0.813845 (rank : 356)
Query Neighborhood Hits	470	Target Neighborhood Hits	1186	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

FBX30_HUMAN
NC score	0.028582 (rank : 599)	θ value	2.36792 (rank : 395)
Query Neighborhood Hits	470	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TB52, Q9BXZ7	Gene names	FBXO30, FBX30
Domain Architecture
Description	F-box only protein 30.

SMC3_MOUSE
NC score	0.028414 (rank : 600)	θ value	0.813845 (rank : 357)
Query Neighborhood Hits	470	Target Neighborhood Hits	1187	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

RNF14_MOUSE
NC score	0.028106 (rank : 601)	θ value	1.81305 (rank : 393)
Query Neighborhood Hits	470	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

EEA1_HUMAN
NC score	0.026421 (rank : 602)	θ value	6.88961 (rank : 445)
Query Neighborhood Hits	470	Target Neighborhood Hits	1796	Shared Neighborhood Hits	112
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CP250_MOUSE
NC score	0.026209 (rank : 603)	θ value	0.62314 (rank : 343)
Query Neighborhood Hits	470	Target Neighborhood Hits	1583	Shared Neighborhood Hits	91
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CP250_HUMAN
NC score	0.026201 (rank : 604)	θ value	1.81305 (rank : 389)
Query Neighborhood Hits	470	Target Neighborhood Hits	1805	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MYLIP_MOUSE
NC score	0.025974 (rank : 605)	θ value	0.813845 (rank : 355)
Query Neighborhood Hits	470	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

EEA1_MOUSE
NC score	0.025273 (rank : 606)	θ value	5.27518 (rank : 428)
Query Neighborhood Hits	470	Target Neighborhood Hits	1637	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GCC2_MOUSE
NC score	0.023720 (rank : 607)	θ value	5.27518 (rank : 430)
Query Neighborhood Hits	470	Target Neighborhood Hits	1619	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CP135_MOUSE
NC score	0.023244 (rank : 608)	θ value	4.03905 (rank : 410)
Query Neighborhood Hits	470	Target Neighborhood Hits	1278	Shared Neighborhood Hits	74
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CEP63_HUMAN
NC score	0.023017 (rank : 609)	θ value	0.813845 (rank : 353)
Query Neighborhood Hits	470	Target Neighborhood Hits	1005	Shared Neighborhood Hits	64
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

FBX30_MOUSE
NC score	0.021939 (rank : 610)	θ value	5.27518 (rank : 429)
Query Neighborhood Hits	470	Target Neighborhood Hits	33	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BJL1, Q8CI21, Q9D9X5	Gene names	Fbxo30
Domain Architecture
Description	F-box only protein 30.

GOGA3_MOUSE
NC score	0.021713 (rank : 611)	θ value	1.38821 (rank : 375)
Query Neighborhood Hits	470	Target Neighborhood Hits	1437	Shared Neighborhood Hits	85
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

PIBF1_HUMAN
NC score	0.021641 (rank : 612)	θ value	5.27518 (rank : 435)
Query Neighborhood Hits	470	Target Neighborhood Hits	1041	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

HOOK1_MOUSE
NC score	0.021567 (rank : 613)	θ value	1.38821 (rank : 376)
Query Neighborhood Hits	470	Target Neighborhood Hits	910	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

GOGA4_HUMAN
NC score	0.020140 (rank : 614)	θ value	6.88961 (rank : 447)
Query Neighborhood Hits	470	Target Neighborhood Hits	2034	Shared Neighborhood Hits	106
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RFIP3_HUMAN
NC score	0.019141 (rank : 615)	θ value	4.03905 (rank : 417)
Query Neighborhood Hits	470	Target Neighborhood Hits	1055	Shared Neighborhood Hits	57
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

KTN1_MOUSE
NC score	0.019128 (rank : 616)	θ value	1.81305 (rank : 390)
Query Neighborhood Hits	470	Target Neighborhood Hits	1324	Shared Neighborhood Hits	77
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

POF1B_HUMAN
NC score	0.018992 (rank : 617)	θ value	2.36792 (rank : 400)
Query Neighborhood Hits	470	Target Neighborhood Hits	494	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

CYLN2_MOUSE
NC score	0.018362 (rank : 618)	θ value	4.03905 (rank : 411)
Query Neighborhood Hits	470	Target Neighborhood Hits	1002	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

HOOK1_HUMAN
NC score	0.017374 (rank : 619)	θ value	5.27518 (rank : 431)
Query Neighborhood Hits	470	Target Neighborhood Hits	942	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

LIPA1_HUMAN
NC score	0.017093 (rank : 620)	θ value	8.99809 (rank : 459)
Query Neighborhood Hits	470	Target Neighborhood Hits	1294	Shared Neighborhood Hits	64
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

EP15R_HUMAN
NC score	0.015915 (rank : 621)	θ value	6.88961 (rank : 446)
Query Neighborhood Hits	470	Target Neighborhood Hits	1083	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

ZBED4_HUMAN
NC score	0.014463 (rank : 622)	θ value	6.88961 (rank : 453)
Query Neighborhood Hits	470	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O75132, Q9UGG8	Gene names	ZBED4, KIAA0637
Domain Architecture
Description	Zinc finger BED domain-containing protein 4.

LUZP1_MOUSE
NC score	0.013153 (rank : 623)	θ value	8.99809 (rank : 460)
Query Neighborhood Hits	470	Target Neighborhood Hits	940	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

ANR26_MOUSE
NC score	0.012936 (rank : 624)	θ value	5.27518 (rank : 421)
Query Neighborhood Hits	470	Target Neighborhood Hits	1554	Shared Neighborhood Hits	70
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ZN330_HUMAN
NC score	0.012763 (rank : 625)	θ value	5.27518 (rank : 438)
Query Neighborhood Hits	470	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ZN330_MOUSE
NC score	0.012659 (rank : 626)	θ value	5.27518 (rank : 439)
Query Neighborhood Hits	470	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q922H9, Q8C389, Q8K2M4	Gene names	Znf330, Noa36, Zfp330
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

TXLNA_MOUSE
NC score	0.011841 (rank : 627)	θ value	8.99809 (rank : 468)
Query Neighborhood Hits	470	Target Neighborhood Hits	846	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PAM1, Q6P1E5	Gene names	Txlna, Txln
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

DIP2A_MOUSE
NC score	0.011714 (rank : 628)	θ value	5.27518 (rank : 427)
Query Neighborhood Hits	470	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIAP1_MOUSE
NC score	0.011313 (rank : 629)	θ value	6.88961 (rank : 443)
Query Neighborhood Hits	470	Target Neighborhood Hits	839	Shared Neighborhood Hits	46
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

PHF14_MOUSE
NC score	0.010065 (rank : 630)	θ value	4.03905 (rank : 416)
Query Neighborhood Hits	470	Target Neighborhood Hits	342	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

MMRN1_HUMAN
NC score	0.009730 (rank : 631)	θ value	4.03905 (rank : 414)
Query Neighborhood Hits	470	Target Neighborhood Hits	636	Shared Neighborhood Hits	32
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

PHF14_HUMAN
NC score	0.009559 (rank : 632)	θ value	4.03905 (rank : 415)
Query Neighborhood Hits	470	Target Neighborhood Hits	447	Shared Neighborhood Hits	27
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

BPA1_MOUSE
NC score	0.008803 (rank : 633)	θ value	8.99809 (rank : 454)
Query Neighborhood Hits	470	Target Neighborhood Hits	1477	Shared Neighborhood Hits	64
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DIP2A_HUMAN
NC score	0.007650 (rank : 634)	θ value	8.99809 (rank : 455)
Query Neighborhood Hits	470	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

ZAN_MOUSE
NC score	0.000328 (rank : 635)	θ value	0.365318 (rank : 329)
Query Neighborhood Hits	470	Target Neighborhood Hits	808	Shared Neighborhood Hits	10
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MMGL_MOUSE
NC score	-0.000508 (rank : 636)	θ value	8.99809 (rank : 462)
Query Neighborhood Hits	470	Target Neighborhood Hits	270	Shared Neighborhood Hits	16
SwissProt Accessions	P49300	Gene names	Mgl1, Mgl
Domain Architecture
Description	Macrophage asialoglycoprotein-binding protein 1 (M-ASGP-BP) (Macrophage galactose/N-acetylgalactosamine-specific lectin) (MMGL).

LRP1B_HUMAN
NC score	-0.003986 (rank : 637)	θ value	5.27518 (rank : 432)
Query Neighborhood Hits	470	Target Neighborhood Hits	602	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FATH_HUMAN
NC score	-0.005067 (rank : 638)	θ value	1.38821 (rank : 374)
Query Neighborhood Hits	470	Target Neighborhood Hits	570	Shared Neighborhood Hits	6
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

M3KL4_HUMAN
NC score	-0.014207 (rank : 639)	θ value	4.03905 (rank : 412)
Query Neighborhood Hits	470	Target Neighborhood Hits	1087	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).