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Network neighborhood for query Sequence : RN169_HUMAN

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RN169_HUMAN
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RN169_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	203	Target Neighborhood Hits	203	Shared Neighborhood Hits	203
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN168_HUMAN
θ value	3.89403e-11 (rank : 2)	NC score	0.520774 (rank : 2)
Query Neighborhood Hits	203	Target Neighborhood Hits	370	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	7.59969e-07 (rank : 3)	NC score	0.472125 (rank : 3)
Query Neighborhood Hits	203	Target Neighborhood Hits	440	Shared Neighborhood Hits	122
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RO52_HUMAN
θ value	1.87187e-05 (rank : 4)	NC score	0.390536 (rank : 21)
Query Neighborhood Hits	203	Target Neighborhood Hits	419	Shared Neighborhood Hits	131
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI35_HUMAN
θ value	1.87187e-05 (rank : 5)	NC score	0.425480 (rank : 6)
Query Neighborhood Hits	203	Target Neighborhood Hits	382	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRIM7_HUMAN
θ value	9.29e-05 (rank : 6)	NC score	0.398223 (rank : 15)
Query Neighborhood Hits	203	Target Neighborhood Hits	336	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI25_HUMAN
θ value	0.000158464 (rank : 7)	NC score	0.409532 (rank : 10)
Query Neighborhood Hits	203	Target Neighborhood Hits	472	Shared Neighborhood Hits	126
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRIM4_HUMAN
θ value	0.000270298 (rank : 8)	NC score	0.407038 (rank : 12)
Query Neighborhood Hits	203	Target Neighborhood Hits	321	Shared Neighborhood Hits	120
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI65_HUMAN
θ value	0.00035302 (rank : 9)	NC score	0.452179 (rank : 4)
Query Neighborhood Hits	203	Target Neighborhood Hits	330	Shared Neighborhood Hits	120
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RO52_MOUSE
θ value	0.000461057 (rank : 10)	NC score	0.387778 (rank : 23)
Query Neighborhood Hits	203	Target Neighborhood Hits	360	Shared Neighborhood Hits	126
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI25_MOUSE
θ value	0.000461057 (rank : 11)	NC score	0.416767 (rank : 8)
Query Neighborhood Hits	203	Target Neighborhood Hits	446	Shared Neighborhood Hits	126
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI35_MOUSE
θ value	0.000786445 (rank : 12)	NC score	0.423235 (rank : 7)
Query Neighborhood Hits	203	Target Neighborhood Hits	465	Shared Neighborhood Hits	129
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI11_MOUSE
θ value	0.00175202 (rank : 13)	NC score	0.385346 (rank : 28)
Query Neighborhood Hits	203	Target Neighborhood Hits	329	Shared Neighborhood Hits	119
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

RKHD1_HUMAN
θ value	0.00298849 (rank : 14)	NC score	0.252818 (rank : 115)
Query Neighborhood Hits	203	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

TRI11_HUMAN
θ value	0.00298849 (rank : 15)	NC score	0.383773 (rank : 30)
Query Neighborhood Hits	203	Target Neighborhood Hits	316	Shared Neighborhood Hits	118
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

RN166_HUMAN
θ value	0.00390308 (rank : 16)	NC score	0.397183 (rank : 16)
Query Neighborhood Hits	203	Target Neighborhood Hits	240	Shared Neighborhood Hits	105
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	0.00390308 (rank : 17)	NC score	0.393364 (rank : 18)
Query Neighborhood Hits	203	Target Neighborhood Hits	248	Shared Neighborhood Hits	104
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI65_MOUSE
θ value	0.00390308 (rank : 18)	NC score	0.431839 (rank : 5)
Query Neighborhood Hits	203	Target Neighborhood Hits	340	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CBL_HUMAN
θ value	0.0113563 (rank : 19)	NC score	0.277530 (rank : 91)
Query Neighborhood Hits	203	Target Neighborhood Hits	353	Shared Neighborhood Hits	97
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.0113563 (rank : 20)	NC score	0.273929 (rank : 95)
Query Neighborhood Hits	203	Target Neighborhood Hits	426	Shared Neighborhood Hits	100
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TRI10_MOUSE
θ value	0.0113563 (rank : 21)	NC score	0.391606 (rank : 20)
Query Neighborhood Hits	203	Target Neighborhood Hits	285	Shared Neighborhood Hits	114
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

CBLB_HUMAN
θ value	0.0148317 (rank : 22)	NC score	0.275215 (rank : 93)
Query Neighborhood Hits	203	Target Neighborhood Hits	261	Shared Neighborhood Hits	92
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0.0148317 (rank : 23)	NC score	0.276358 (rank : 92)
Query Neighborhood Hits	203	Target Neighborhood Hits	277	Shared Neighborhood Hits	94
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

TRAF6_HUMAN
θ value	0.0148317 (rank : 24)	NC score	0.264272 (rank : 100)
Query Neighborhood Hits	203	Target Neighborhood Hits	267	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	0.0148317 (rank : 25)	NC score	0.268191 (rank : 97)
Query Neighborhood Hits	203	Target Neighborhood Hits	255	Shared Neighborhood Hits	106
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI56_HUMAN
θ value	0.0148317 (rank : 26)	NC score	0.332764 (rank : 71)
Query Neighborhood Hits	203	Target Neighborhood Hits	339	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRIM6_MOUSE
θ value	0.0148317 (rank : 27)	NC score	0.373292 (rank : 41)
Query Neighborhood Hits	203	Target Neighborhood Hits	451	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI47_HUMAN
θ value	0.0193708 (rank : 28)	NC score	0.386798 (rank : 24)
Query Neighborhood Hits	203	Target Neighborhood Hits	286	Shared Neighborhood Hits	110
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI26_HUMAN
θ value	0.0252991 (rank : 29)	NC score	0.407955 (rank : 11)
Query Neighborhood Hits	203	Target Neighborhood Hits	335	Shared Neighborhood Hits	122
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	0.0252991 (rank : 30)	NC score	0.406197 (rank : 13)
Query Neighborhood Hits	203	Target Neighborhood Hits	339	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI27_MOUSE
θ value	0.0252991 (rank : 31)	NC score	0.370681 (rank : 45)
Query Neighborhood Hits	203	Target Neighborhood Hits	261	Shared Neighborhood Hits	116
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI27_HUMAN
θ value	0.0330416 (rank : 32)	NC score	0.368666 (rank : 47)
Query Neighborhood Hits	203	Target Neighborhood Hits	273	Shared Neighborhood Hits	115
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI60_HUMAN
θ value	0.0330416 (rank : 33)	NC score	0.386720 (rank : 25)
Query Neighborhood Hits	203	Target Neighborhood Hits	357	Shared Neighborhood Hits	123
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRIM7_MOUSE
θ value	0.0431538 (rank : 34)	NC score	0.385331 (rank : 29)
Query Neighborhood Hits	203	Target Neighborhood Hits	358	Shared Neighborhood Hits	111
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

BIRC7_HUMAN
θ value	0.0563607 (rank : 35)	NC score	0.248843 (rank : 118)
Query Neighborhood Hits	203	Target Neighborhood Hits	185	Shared Neighborhood Hits	98
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CBLC_MOUSE
θ value	0.0563607 (rank : 36)	NC score	0.267191 (rank : 98)
Query Neighborhood Hits	203	Target Neighborhood Hits	186	Shared Neighborhood Hits	79
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

ZN313_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.392047 (rank : 19)
Query Neighborhood Hits	203	Target Neighborhood Hits	264	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

PML_MOUSE
θ value	0.0736092 (rank : 38)	NC score	0.244943 (rank : 121)
Query Neighborhood Hits	203	Target Neighborhood Hits	246	Shared Neighborhood Hits	94
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI34_HUMAN
θ value	0.0736092 (rank : 39)	NC score	0.365382 (rank : 52)
Query Neighborhood Hits	203	Target Neighborhood Hits	416	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI52_HUMAN
θ value	0.0736092 (rank : 40)	NC score	0.413102 (rank : 9)
Query Neighborhood Hits	203	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

ZN313_MOUSE
θ value	0.0736092 (rank : 41)	NC score	0.394982 (rank : 17)
Query Neighborhood Hits	203	Target Neighborhood Hits	273	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

CBLC_HUMAN
θ value	0.0961366 (rank : 42)	NC score	0.272588 (rank : 96)
Query Neighborhood Hits	203	Target Neighborhood Hits	173	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

TRI15_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.368076 (rank : 50)
Query Neighborhood Hits	203	Target Neighborhood Hits	395	Shared Neighborhood Hits	115
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI30_MOUSE
θ value	0.0961366 (rank : 44)	NC score	0.386231 (rank : 27)
Query Neighborhood Hits	203	Target Neighborhood Hits	434	Shared Neighborhood Hits	119
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRIM8_HUMAN
θ value	0.0961366 (rank : 45)	NC score	0.372961 (rank : 43)
Query Neighborhood Hits	203	Target Neighborhood Hits	650	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	0.0961366 (rank : 46)	NC score	0.372068 (rank : 44)
Query Neighborhood Hits	203	Target Neighborhood Hits	674	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

AFF4_MOUSE
θ value	0.125558 (rank : 47)	NC score	0.051605 (rank : 296)
Query Neighborhood Hits	203	Target Neighborhood Hits	581	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AL2S4_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.077492 (rank : 256)
Query Neighborhood Hits	203	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q45, Q53TS9, Q53TT2, Q7Z3B6, Q8IZ18, Q8NBF8, Q96CY1	Gene names	ALS2CR4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein.

PML_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.257219 (rank : 112)
Query Neighborhood Hits	203	Target Neighborhood Hits	248	Shared Neighborhood Hits	92
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRI10_HUMAN
θ value	0.125558 (rank : 50)	NC score	0.388873 (rank : 22)
Query Neighborhood Hits	203	Target Neighborhood Hits	315	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI17_HUMAN
θ value	0.125558 (rank : 51)	NC score	0.376699 (rank : 37)
Query Neighborhood Hits	203	Target Neighborhood Hits	318	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

EHMT2_MOUSE
θ value	0.163984 (rank : 52)	NC score	0.025630 (rank : 327)
Query Neighborhood Hits	203	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MARK2_HUMAN
θ value	0.163984 (rank : 53)	NC score	0.002563 (rank : 360)
Query Neighborhood Hits	203	Target Neighborhood Hits	1056	Shared Neighborhood Hits	9
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

RN141_HUMAN
θ value	0.163984 (rank : 54)	NC score	0.237487 (rank : 127)
Query Neighborhood Hits	203	Target Neighborhood Hits	199	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.163984 (rank : 55)	NC score	0.237168 (rank : 128)
Query Neighborhood Hits	203	Target Neighborhood Hits	200	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RNF39_HUMAN
θ value	0.163984 (rank : 56)	NC score	0.337828 (rank : 68)
Query Neighborhood Hits	203	Target Neighborhood Hits	200	Shared Neighborhood Hits	99
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI39_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.376519 (rank : 38)
Query Neighborhood Hits	203	Target Neighborhood Hits	691	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM5_HUMAN
θ value	0.163984 (rank : 58)	NC score	0.379091 (rank : 33)
Query Neighborhood Hits	203	Target Neighborhood Hits	424	Shared Neighborhood Hits	121
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

ASPX_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.084760 (rank : 246)
Query Neighborhood Hits	203	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

ASXL1_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.060985 (rank : 280)
Query Neighborhood Hits	203	Target Neighborhood Hits	260	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

RN125_HUMAN
θ value	0.21417 (rank : 61)	NC score	0.375659 (rank : 39)
Query Neighborhood Hits	203	Target Neighborhood Hits	230	Shared Neighborhood Hits	107
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI39_HUMAN
θ value	0.21417 (rank : 62)	NC score	0.377850 (rank : 35)
Query Neighborhood Hits	203	Target Neighborhood Hits	693	Shared Neighborhood Hits	137
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI40_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.399441 (rank : 14)
Query Neighborhood Hits	203	Target Neighborhood Hits	279	Shared Neighborhood Hits	111
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI47_MOUSE
θ value	0.21417 (rank : 64)	NC score	0.379266 (rank : 32)
Query Neighborhood Hits	203	Target Neighborhood Hits	295	Shared Neighborhood Hits	109
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

IWS1_HUMAN
θ value	0.365318 (rank : 65)	NC score	0.053207 (rank : 290)
Query Neighborhood Hits	203	Target Neighborhood Hits	1241	Shared Neighborhood Hits	38
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SDPR_MOUSE
θ value	0.365318 (rank : 66)	NC score	0.055114 (rank : 286)
Query Neighborhood Hits	203	Target Neighborhood Hits	485	Shared Neighborhood Hits	26
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TRI59_MOUSE
θ value	0.365318 (rank : 67)	NC score	0.361851 (rank : 54)
Query Neighborhood Hits	203	Target Neighborhood Hits	292	Shared Neighborhood Hits	109
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

ZRAB2_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.093769 (rank : 235)
Query Neighborhood Hits	203	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

BFAR_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.339199 (rank : 67)
Query Neighborhood Hits	203	Target Neighborhood Hits	222	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

FX4L1_HUMAN
θ value	0.47712 (rank : 70)	NC score	0.016720 (rank : 344)
Query Neighborhood Hits	203	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NU39	Gene names	FOXD4L1
Domain Architecture
Description	Forkhead box protein D4-like 1.

SPAT2_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.081604 (rank : 250)
Query Neighborhood Hits	203	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

TRI59_HUMAN
θ value	0.47712 (rank : 72)	NC score	0.359780 (rank : 56)
Query Neighborhood Hits	203	Target Neighborhood Hits	307	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI68_HUMAN
θ value	0.47712 (rank : 73)	NC score	0.366041 (rank : 51)
Query Neighborhood Hits	203	Target Neighborhood Hits	267	Shared Neighborhood Hits	113
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

UHRF2_HUMAN
θ value	0.47712 (rank : 74)	NC score	0.225609 (rank : 141)
Query Neighborhood Hits	203	Target Neighborhood Hits	269	Shared Neighborhood Hits	101
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	0.47712 (rank : 75)	NC score	0.225972 (rank : 138)
Query Neighborhood Hits	203	Target Neighborhood Hits	275	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BPTF_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.046126 (rank : 300)
Query Neighborhood Hits	203	Target Neighborhood Hits	786	Shared Neighborhood Hits	28
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CT077_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.069793 (rank : 264)
Query Neighborhood Hits	203	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CSU0, Q3U8H1, Q3UGH1, Q3USX3, Q6GTJ6	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf77 homolog.

FA50A_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.064017 (rank : 273)
Query Neighborhood Hits	203	Target Neighborhood Hits	264	Shared Neighborhood Hits	17
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

IWS1_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.052525 (rank : 292)
Query Neighborhood Hits	203	Target Neighborhood Hits	1258	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PCLO_MOUSE
θ value	0.62314 (rank : 80)	NC score	0.039571 (rank : 306)
Query Neighborhood Hits	203	Target Neighborhood Hits	2275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PEX10_HUMAN
θ value	0.62314 (rank : 81)	NC score	0.357418 (rank : 58)
Query Neighborhood Hits	203	Target Neighborhood Hits	255	Shared Neighborhood Hits	104
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RAI14_MOUSE
θ value	0.62314 (rank : 82)	NC score	0.031027 (rank : 319)
Query Neighborhood Hits	203	Target Neighborhood Hits	1505	Shared Neighborhood Hits	52
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TRI17_MOUSE
θ value	0.62314 (rank : 83)	NC score	0.364722 (rank : 53)
Query Neighborhood Hits	203	Target Neighborhood Hits	620	Shared Neighborhood Hits	125
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI32_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.327928 (rank : 73)
Query Neighborhood Hits	203	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRIM1_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.281148 (rank : 89)
Query Neighborhood Hits	203	Target Neighborhood Hits	345	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.278586 (rank : 90)
Query Neighborhood Hits	203	Target Neighborhood Hits	361	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM6_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.368596 (rank : 48)
Query Neighborhood Hits	203	Target Neighborhood Hits	412	Shared Neighborhood Hits	114
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

AKA12_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.052457 (rank : 293)
Query Neighborhood Hits	203	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

BPA1_MOUSE
θ value	0.813845 (rank : 89)	NC score	0.029528 (rank : 323)
Query Neighborhood Hits	203	Target Neighborhood Hits	1477	Shared Neighborhood Hits	50
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

E41L2_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.024493 (rank : 331)
Query Neighborhood Hits	203	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.084552 (rank : 247)
Query Neighborhood Hits	203	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RFFL_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.131179 (rank : 196)
Query Neighborhood Hits	203	Target Neighborhood Hits	175	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	0.813845 (rank : 93)	NC score	0.130448 (rank : 199)
Query Neighborhood Hits	203	Target Neighborhood Hits	145	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

TRI43_HUMAN
θ value	0.813845 (rank : 94)	NC score	0.380732 (rank : 31)
Query Neighborhood Hits	203	Target Neighborhood Hits	341	Shared Neighborhood Hits	124
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI50_MOUSE
θ value	0.813845 (rank : 95)	NC score	0.368565 (rank : 49)
Query Neighborhood Hits	203	Target Neighborhood Hits	326	Shared Neighborhood Hits	123
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

BFAR_MOUSE
θ value	1.06291 (rank : 96)	NC score	0.335806 (rank : 70)
Query Neighborhood Hits	203	Target Neighborhood Hits	232	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

CPLX4_HUMAN
θ value	1.06291 (rank : 97)	NC score	0.045471 (rank : 301)
Query Neighborhood Hits	203	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z7G2	Gene names	CPLX4
Domain Architecture	No domain graphic available
Description	Complexin-4 (Complexin IV) (CPX IV).

CT077_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.065923 (rank : 269)
Query Neighborhood Hits	203	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

EGFL7_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.020237 (rank : 339)
Query Neighborhood Hits	203	Target Neighborhood Hits	325	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

FA50A_MOUSE
θ value	1.06291 (rank : 100)	NC score	0.059150 (rank : 284)
Query Neighborhood Hits	203	Target Neighborhood Hits	293	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

MD1L1_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.038395 (rank : 307)
Query Neighborhood Hits	203	Target Neighborhood Hits	893	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

PCLO_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.043002 (rank : 302)
Query Neighborhood Hits	203	Target Neighborhood Hits	2046	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TRI18_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.284206 (rank : 86)
Query Neighborhood Hits	203	Target Neighborhood Hits	307	Shared Neighborhood Hits	106
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	1.06291 (rank : 104)	NC score	0.283918 (rank : 87)
Query Neighborhood Hits	203	Target Neighborhood Hits	292	Shared Neighborhood Hits	106
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI50_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.368712 (rank : 46)
Query Neighborhood Hits	203	Target Neighborhood Hits	294	Shared Neighborhood Hits	116
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI73_HUMAN
θ value	1.06291 (rank : 106)	NC score	0.376920 (rank : 36)
Query Neighborhood Hits	203	Target Neighborhood Hits	258	Shared Neighborhood Hits	114
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.375043 (rank : 40)
Query Neighborhood Hits	203	Target Neighborhood Hits	249	Shared Neighborhood Hits	112
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

CROCC_MOUSE
θ value	1.38821 (rank : 108)	NC score	0.035078 (rank : 312)
Query Neighborhood Hits	203	Target Neighborhood Hits	1460	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

EXO1_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.041703 (rank : 303)
Query Neighborhood Hits	203	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

TRI41_HUMAN
θ value	1.38821 (rank : 110)	NC score	0.355004 (rank : 60)
Query Neighborhood Hits	203	Target Neighborhood Hits	349	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI56_MOUSE
θ value	1.38821 (rank : 111)	NC score	0.309701 (rank : 76)
Query Neighborhood Hits	203	Target Neighborhood Hits	255	Shared Neighborhood Hits	115
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

ZSCA4_HUMAN
θ value	1.38821 (rank : 112)	NC score	-0.001752 (rank : 363)
Query Neighborhood Hits	203	Target Neighborhood Hits	713	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NAM6	Gene names	ZSCAN4, ZNF494
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494).

ADA15_HUMAN
θ value	1.81305 (rank : 113)	NC score	0.014113 (rank : 349)
Query Neighborhood Hits	203	Target Neighborhood Hits	288	Shared Neighborhood Hits	6
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

AMFR_MOUSE
θ value	1.81305 (rank : 114)	NC score	0.166146 (rank : 170)
Query Neighborhood Hits	203	Target Neighborhood Hits	208	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

CENPE_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.035025 (rank : 313)
Query Neighborhood Hits	203	Target Neighborhood Hits	2060	Shared Neighborhood Hits	79
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CLIC6_HUMAN
θ value	1.81305 (rank : 116)	NC score	0.023172 (rank : 335)
Query Neighborhood Hits	203	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

DAB2P_MOUSE
θ value	1.81305 (rank : 117)	NC score	0.025404 (rank : 328)
Query Neighborhood Hits	203	Target Neighborhood Hits	284	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

DDX54_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.013523 (rank : 350)
Query Neighborhood Hits	203	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DIDO1_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.030005 (rank : 322)
Query Neighborhood Hits	203	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DTX3_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.196209 (rank : 163)
Query Neighborhood Hits	203	Target Neighborhood Hits	198	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DUS1L_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.038225 (rank : 308)
Query Neighborhood Hits	203	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1R4, Q96AI3	Gene names	DUS1L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

RN123_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.125610 (rank : 203)
Query Neighborhood Hits	203	Target Neighborhood Hits	175	Shared Neighborhood Hits	74
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RPTOR_MOUSE
θ value	1.81305 (rank : 123)	NC score	0.030603 (rank : 320)
Query Neighborhood Hits	203	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

TCAL5_HUMAN
θ value	1.81305 (rank : 124)	NC score	0.031647 (rank : 317)
Query Neighborhood Hits	203	Target Neighborhood Hits	806	Shared Neighborhood Hits	26
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TRI22_HUMAN
θ value	1.81305 (rank : 125)	NC score	0.373107 (rank : 42)
Query Neighborhood Hits	203	Target Neighborhood Hits	396	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI32_MOUSE
θ value	1.81305 (rank : 126)	NC score	0.320554 (rank : 74)
Query Neighborhood Hits	203	Target Neighborhood Hits	271	Shared Neighborhood Hits	101
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRIM2_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.301210 (rank : 77)
Query Neighborhood Hits	203	Target Neighborhood Hits	330	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.300498 (rank : 78)
Query Neighborhood Hits	203	Target Neighborhood Hits	331	Shared Neighborhood Hits	109
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

GON4L_MOUSE
θ value	2.36792 (rank : 129)	NC score	0.034361 (rank : 314)
Query Neighborhood Hits	203	Target Neighborhood Hits	455	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MAT1_HUMAN
θ value	2.36792 (rank : 130)	NC score	0.097724 (rank : 231)
Query Neighborhood Hits	203	Target Neighborhood Hits	179	Shared Neighborhood Hits	39
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

RN123_MOUSE
θ value	2.36792 (rank : 131)	NC score	0.123919 (rank : 204)
Query Neighborhood Hits	203	Target Neighborhood Hits	174	Shared Neighborhood Hits	73
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRHY_HUMAN
θ value	2.36792 (rank : 132)	NC score	0.038074 (rank : 309)
Query Neighborhood Hits	203	Target Neighborhood Hits	1385	Shared Neighborhood Hits	55
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRI38_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.352923 (rank : 62)
Query Neighborhood Hits	203	Target Neighborhood Hits	373	Shared Neighborhood Hits	112
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI63_HUMAN
θ value	2.36792 (rank : 134)	NC score	0.294385 (rank : 83)
Query Neighborhood Hits	203	Target Neighborhood Hits	298	Shared Neighborhood Hits	98
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

ADA15_MOUSE
θ value	3.0926 (rank : 135)	NC score	0.014266 (rank : 348)
Query Neighborhood Hits	203	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

BARD1_MOUSE
θ value	3.0926 (rank : 136)	NC score	0.082480 (rank : 249)
Query Neighborhood Hits	203	Target Neighborhood Hits	411	Shared Neighborhood Hits	64
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BPAEA_MOUSE
θ value	3.0926 (rank : 137)	NC score	0.034167 (rank : 315)
Query Neighborhood Hits	203	Target Neighborhood Hits	1480	Shared Neighborhood Hits	62
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRE1B_HUMAN
θ value	3.0926 (rank : 138)	NC score	0.080838 (rank : 252)
Query Neighborhood Hits	203	Target Neighborhood Hits	1040	Shared Neighborhood Hits	103
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	3.0926 (rank : 139)	NC score	0.080886 (rank : 251)
Query Neighborhood Hits	203	Target Neighborhood Hits	970	Shared Neighborhood Hits	99
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

ITB6_MOUSE
θ value	3.0926 (rank : 140)	NC score	0.010170 (rank : 354)
Query Neighborhood Hits	203	Target Neighborhood Hits	341	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

MLL2_HUMAN
θ value	3.0926 (rank : 141)	NC score	0.041389 (rank : 304)
Query Neighborhood Hits	203	Target Neighborhood Hits	1788	Shared Neighborhood Hits	56
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PZRN3_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.152754 (rank : 179)
Query Neighborhood Hits	203	Target Neighborhood Hits	461	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	3.0926 (rank : 143)	NC score	0.153613 (rank : 178)
Query Neighborhood Hits	203	Target Neighborhood Hits	447	Shared Neighborhood Hits	103
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RAG1_MOUSE
θ value	3.0926 (rank : 144)	NC score	0.261697 (rank : 106)
Query Neighborhood Hits	203	Target Neighborhood Hits	189	Shared Neighborhood Hits	90
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RN125_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.358866 (rank : 57)
Query Neighborhood Hits	203	Target Neighborhood Hits	220	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI55_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.298606 (rank : 80)
Query Neighborhood Hits	203	Target Neighborhood Hits	292	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI63_MOUSE
θ value	3.0926 (rank : 147)	NC score	0.299719 (rank : 79)
Query Neighborhood Hits	203	Target Neighborhood Hits	240	Shared Neighborhood Hits	92
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

ZN318_MOUSE
θ value	3.0926 (rank : 148)	NC score	0.031723 (rank : 316)
Query Neighborhood Hits	203	Target Neighborhood Hits	642	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

BIRC8_HUMAN
θ value	4.03905 (rank : 149)	NC score	0.119744 (rank : 205)
Query Neighborhood Hits	203	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CCD93_MOUSE
θ value	4.03905 (rank : 150)	NC score	0.028648 (rank : 325)
Query Neighborhood Hits	203	Target Neighborhood Hits	362	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CNTRB_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.036303 (rank : 311)
Query Neighborhood Hits	203	Target Neighborhood Hits	1029	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

DDX27_MOUSE
θ value	4.03905 (rank : 152)	NC score	0.010889 (rank : 353)
Query Neighborhood Hits	203	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DTX3_MOUSE
θ value	4.03905 (rank : 153)	NC score	0.193208 (rank : 165)
Query Neighborhood Hits	203	Target Neighborhood Hits	202	Shared Neighborhood Hits	92
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

FA50B_MOUSE
θ value	4.03905 (rank : 154)	NC score	0.053805 (rank : 289)
Query Neighborhood Hits	203	Target Neighborhood Hits	186	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WTJ8, Q80X84, Q9D993	Gene names	Fam50b, D0H6S2654E, X5l
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

FRAS1_HUMAN
θ value	4.03905 (rank : 155)	NC score	0.007442 (rank : 356)
Query Neighborhood Hits	203	Target Neighborhood Hits	759	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

RAG1_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.262095 (rank : 105)
Query Neighborhood Hits	203	Target Neighborhood Hits	203	Shared Neighborhood Hits	86
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RN146_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.232276 (rank : 132)
Query Neighborhood Hits	203	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.229612 (rank : 134)
Query Neighborhood Hits	203	Target Neighborhood Hits	161	Shared Neighborhood Hits	88
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

SASH1_MOUSE
θ value	4.03905 (rank : 159)	NC score	0.024238 (rank : 332)
Query Neighborhood Hits	203	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

TRI54_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.283161 (rank : 88)
Query Neighborhood Hits	203	Target Neighborhood Hits	209	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.285150 (rank : 85)
Query Neighborhood Hits	203	Target Neighborhood Hits	197	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

Z3H7A_HUMAN
θ value	4.03905 (rank : 162)	NC score	0.023354 (rank : 334)
Query Neighborhood Hits	203	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

SMCA4_HUMAN
θ value	5.27518 (rank : 163)	NC score	0.015137 (rank : 346)
Query Neighborhood Hits	203	Target Neighborhood Hits	597	Shared Neighborhood Hits	24
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SP100_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.013306 (rank : 351)
Query Neighborhood Hits	203	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

SYCP1_MOUSE
θ value	5.27518 (rank : 165)	NC score	0.041036 (rank : 305)
Query Neighborhood Hits	203	Target Neighborhood Hits	1456	Shared Neighborhood Hits	64
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TIF1B_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.136570 (rank : 190)
Query Neighborhood Hits	203	Target Neighborhood Hits	312	Shared Neighborhood Hits	80
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI34_MOUSE
θ value	5.27518 (rank : 167)	NC score	0.345394 (rank : 64)
Query Neighborhood Hits	203	Target Neighborhood Hits	332	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

UHRF1_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.188078 (rank : 167)
Query Neighborhood Hits	203	Target Neighborhood Hits	278	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

VASN_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.003110 (rank : 359)
Query Neighborhood Hits	203	Target Neighborhood Hits	449	Shared Neighborhood Hits	5
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

AMFR2_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.157336 (rank : 176)
Query Neighborhood Hits	203	Target Neighborhood Hits	219	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

BIRC3_MOUSE
θ value	6.88961 (rank : 171)	NC score	0.092118 (rank : 237)
Query Neighborhood Hits	203	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

CAC1G_HUMAN
θ value	6.88961 (rank : 172)	NC score	0.008502 (rank : 355)
Query Neighborhood Hits	203	Target Neighborhood Hits	587	Shared Neighborhood Hits	13
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

MAST4_HUMAN
θ value	6.88961 (rank : 173)	NC score	0.001533 (rank : 361)
Query Neighborhood Hits	203	Target Neighborhood Hits	1804	Shared Neighborhood Hits	33
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MAT1_MOUSE
θ value	6.88961 (rank : 174)	NC score	0.086387 (rank : 245)
Query Neighborhood Hits	203	Target Neighborhood Hits	217	Shared Neighborhood Hits	40
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MCES_MOUSE
θ value	6.88961 (rank : 175)	NC score	0.023688 (rank : 333)
Query Neighborhood Hits	203	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0L8, Q3V3U9, Q6ZQC6, Q9D5F1	Gene names	Rnmt, Kiaa0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase).

MD1L1_MOUSE
θ value	6.88961 (rank : 176)	NC score	0.030523 (rank : 321)
Query Neighborhood Hits	203	Target Neighborhood Hits	1001	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MYH7_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.017995 (rank : 340)
Query Neighborhood Hits	203	Target Neighborhood Hits	1559	Shared Neighborhood Hits	55
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PDZD2_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.017794 (rank : 342)
Query Neighborhood Hits	203	Target Neighborhood Hits	772	Shared Neighborhood Hits	24
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PI3R4_MOUSE
θ value	6.88961 (rank : 179)	NC score	0.017931 (rank : 341)
Query Neighborhood Hits	203	Target Neighborhood Hits	535	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

RNF37_MOUSE
θ value	6.88961 (rank : 180)	NC score	0.095628 (rank : 234)
Query Neighborhood Hits	203	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

TBX2_HUMAN
θ value	6.88961 (rank : 181)	NC score	0.006782 (rank : 357)
Query Neighborhood Hits	203	Target Neighborhood Hits	195	Shared Neighborhood Hits	6
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TRIM9_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.220830 (rank : 145)
Query Neighborhood Hits	203	Target Neighborhood Hits	294	Shared Neighborhood Hits	94
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.215646 (rank : 153)
Query Neighborhood Hits	203	Target Neighborhood Hits	274	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TSKS_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.024723 (rank : 329)
Query Neighborhood Hits	203	Target Neighborhood Hits	188	Shared Neighborhood Hits	12
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

TXLNA_HUMAN
θ value	6.88961 (rank : 185)	NC score	0.020849 (rank : 338)
Query Neighborhood Hits	203	Target Neighborhood Hits	982	Shared Neighborhood Hits	28
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UHRF1_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.181961 (rank : 169)
Query Neighborhood Hits	203	Target Neighborhood Hits	272	Shared Neighborhood Hits	100
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

CECR2_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.023011 (rank : 336)
Query Neighborhood Hits	203	Target Neighborhood Hits	543	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CELR3_HUMAN
θ value	8.99809 (rank : 188)	NC score	-0.001081 (rank : 362)
Query Neighborhood Hits	203	Target Neighborhood Hits	680	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CNTRB_HUMAN
θ value	8.99809 (rank : 189)	NC score	0.037212 (rank : 310)
Query Neighborhood Hits	203	Target Neighborhood Hits	690	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

DUS1L_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.028775 (rank : 324)
Query Neighborhood Hits	203	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2P3, Q8VCN7, Q9D124	Gene names	Dus1l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

FANCF_HUMAN
θ value	8.99809 (rank : 191)	NC score	0.024657 (rank : 330)
Query Neighborhood Hits	203	Target Neighborhood Hits	2	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPI8, Q52LM0	Gene names	FANCF
Domain Architecture	No domain graphic available
Description	Fanconi anemia group F protein (Protein FACF).

LMNB1_MOUSE
θ value	8.99809 (rank : 192)	NC score	0.016321 (rank : 345)
Query Neighborhood Hits	203	Target Neighborhood Hits	719	Shared Neighborhood Hits	30
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

MY18A_MOUSE
θ value	8.99809 (rank : 193)	NC score	0.026920 (rank : 326)
Query Neighborhood Hits	203	Target Neighborhood Hits	1989	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NEUL1_HUMAN
θ value	8.99809 (rank : 194)	NC score	0.104176 (rank : 224)
Query Neighborhood Hits	203	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	8.99809 (rank : 195)	NC score	0.104555 (rank : 222)
Query Neighborhood Hits	203	Target Neighborhood Hits	106	Shared Neighborhood Hits	42
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NKTR_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.011343 (rank : 352)
Query Neighborhood Hits	203	Target Neighborhood Hits	658	Shared Neighborhood Hits	18
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NPBL_MOUSE
θ value	8.99809 (rank : 197)	NC score	0.021596 (rank : 337)
Query Neighborhood Hits	203	Target Neighborhood Hits	1041	Shared Neighborhood Hits	25
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PHLPP_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.004994 (rank : 358)
Query Neighborhood Hits	203	Target Neighborhood Hits	604	Shared Neighborhood Hits	13
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PI3R4_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.016859 (rank : 343)
Query Neighborhood Hits	203	Target Neighborhood Hits	534	Shared Neighborhood Hits	7
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

SMCA2_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.014385 (rank : 347)
Query Neighborhood Hits	203	Target Neighborhood Hits	503	Shared Neighborhood Hits	25
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SYCP1_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.031452 (rank : 318)
Query Neighborhood Hits	203	Target Neighborhood Hits	1313	Shared Neighborhood Hits	50
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRI36_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.195991 (rank : 164)
Query Neighborhood Hits	203	Target Neighborhood Hits	266	Shared Neighborhood Hits	93
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRIM3_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.297197 (rank : 81)
Query Neighborhood Hits	203	Target Neighborhood Hits	357	Shared Neighborhood Hits	111
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

ARD1_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.070574 (rank : 263)
Query Neighborhood Hits	203	Target Neighborhood Hits	621	Shared Neighborhood Hits	57
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.075097 (rank : 258)
Query Neighborhood Hits	203	Target Neighborhood Hits	573	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

BARD1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.073224 (rank : 260)
Query Neighborhood Hits	203	Target Neighborhood Hits	427	Shared Neighborhood Hits	60
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BIRC2_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.091040 (rank : 238)
Query Neighborhood Hits	203	Target Neighborhood Hits	142	Shared Neighborhood Hits	66
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.087660 (rank : 242)
Query Neighborhood Hits	203	Target Neighborhood Hits	137	Shared Neighborhood Hits	59
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.097753 (rank : 230)
Query Neighborhood Hits	203	Target Neighborhood Hits	133	Shared Neighborhood Hits	64
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC4_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.063144 (rank : 275)
Query Neighborhood Hits	203	Target Neighborhood Hits	89	Shared Neighborhood Hits	40
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.062470 (rank : 277)
Query Neighborhood Hits	203	Target Neighborhood Hits	89	Shared Neighborhood Hits	40
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BRAP_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.061739 (rank : 278)
Query Neighborhood Hits	203	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.053824 (rank : 288)
Query Neighborhood Hits	203	Target Neighborhood Hits	409	Shared Neighborhood Hits	42
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRCA1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.257818 (rank : 109)
Query Neighborhood Hits	203	Target Neighborhood Hits	381	Shared Neighborhood Hits	114
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.260393 (rank : 107)
Query Neighborhood Hits	203	Target Neighborhood Hits	436	Shared Neighborhood Hits	117
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRE1A_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.066188 (rank : 268)
Query Neighborhood Hits	203	Target Neighborhood Hits	1071	Shared Neighborhood Hits	100
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.065891 (rank : 270)
Query Neighborhood Hits	203	Target Neighborhood Hits	1025	Shared Neighborhood Hits	99
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BSPRY_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.245265 (rank : 120)
Query Neighborhood Hits	203	Target Neighborhood Hits	115	Shared Neighborhood Hits	57
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.263137 (rank : 102)
Query Neighborhood Hits	203	Target Neighborhood Hits	163	Shared Neighborhood Hits	61
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.225036 (rank : 143)
Query Neighborhood Hits	203	Target Neighborhood Hits	322	Shared Neighborhood Hits	49
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.227982 (rank : 136)
Query Neighborhood Hits	203	Target Neighborhood Hits	252	Shared Neighborhood Hits	48
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.216245 (rank : 152)
Query Neighborhood Hits	203	Target Neighborhood Hits	185	Shared Neighborhood Hits	48
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.225711 (rank : 139)
Query Neighborhood Hits	203	Target Neighborhood Hits	191	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.216441 (rank : 151)
Query Neighborhood Hits	203	Target Neighborhood Hits	195	Shared Neighborhood Hits	47
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.220053 (rank : 147)
Query Neighborhood Hits	203	Target Neighborhood Hits	229	Shared Neighborhood Hits	49
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.223289 (rank : 144)
Query Neighborhood Hits	203	Target Neighborhood Hits	233	Shared Neighborhood Hits	48
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.218017 (rank : 149)
Query Neighborhood Hits	203	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.209420 (rank : 156)
Query Neighborhood Hits	203	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.218683 (rank : 148)
Query Neighborhood Hits	203	Target Neighborhood Hits	125	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CHFR_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.231123 (rank : 133)
Query Neighborhood Hits	203	Target Neighborhood Hits	255	Shared Neighborhood Hits	100
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.226334 (rank : 137)
Query Neighborhood Hits	203	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CM007_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.119173 (rank : 206)
Query Neighborhood Hits	203	Target Neighborhood Hits	422	Shared Neighborhood Hits	77
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.135858 (rank : 191)
Query Neighborhood Hits	203	Target Neighborhood Hits	416	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CNOT4_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.067783 (rank : 265)
Query Neighborhood Hits	203	Target Neighborhood Hits	207	Shared Neighborhood Hits	34
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.065540 (rank : 271)
Query Neighborhood Hits	203	Target Neighborhood Hits	277	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

DTX3L_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.096044 (rank : 233)
Query Neighborhood Hits	203	Target Neighborhood Hits	187	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

ERMAP_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.253714 (rank : 113)
Query Neighborhood Hits	203	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.233198 (rank : 130)
Query Neighborhood Hits	203	Target Neighborhood Hits	231	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

FSD1L_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.051619 (rank : 295)
Query Neighborhood Hits	203	Target Neighborhood Hits	78	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

LNX1_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.128413 (rank : 201)
Query Neighborhood Hits	203	Target Neighborhood Hits	379	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.130656 (rank : 197)
Query Neighborhood Hits	203	Target Neighborhood Hits	377	Shared Neighborhood Hits	104
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.131427 (rank : 195)
Query Neighborhood Hits	203	Target Neighborhood Hits	389	Shared Neighborhood Hits	105
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.131644 (rank : 194)
Query Neighborhood Hits	203	Target Neighborhood Hits	407	Shared Neighborhood Hits	105
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LRSM1_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.050063 (rank : 299)
Query Neighborhood Hits	203	Target Neighborhood Hits	1078	Shared Neighborhood Hits	81
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LRSM1_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.051526 (rank : 297)
Query Neighborhood Hits	203	Target Neighborhood Hits	874	Shared Neighborhood Hits	74
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MEFV_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.286345 (rank : 84)
Query Neighborhood Hits	203	Target Neighborhood Hits	431	Shared Neighborhood Hits	75
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.262478 (rank : 103)
Query Neighborhood Hits	203	Target Neighborhood Hits	236	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MGRN1_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.109552 (rank : 215)
Query Neighborhood Hits	203	Target Neighborhood Hits	192	Shared Neighborhood Hits	66
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.110525 (rank : 212)
Query Neighborhood Hits	203	Target Neighborhood Hits	149	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MNAB_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.074078 (rank : 259)
Query Neighborhood Hits	203	Target Neighborhood Hits	196	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.072618 (rank : 261)
Query Neighborhood Hits	203	Target Neighborhood Hits	231	Shared Neighborhood Hits	69
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MYLIP_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.060752 (rank : 282)
Query Neighborhood Hits	203	Target Neighborhood Hits	139	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NHLC1_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.103258 (rank : 225)
Query Neighborhood Hits	203	Target Neighborhood Hits	91	Shared Neighborhood Hits	51
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.130182 (rank : 200)
Query Neighborhood Hits	203	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCGF2_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.086643 (rank : 243)
Query Neighborhood Hits	203	Target Neighborhood Hits	222	Shared Neighborhood Hits	60
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.086616 (rank : 244)
Query Neighborhood Hits	203	Target Neighborhood Hits	213	Shared Neighborhood Hits	60
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.090355 (rank : 239)
Query Neighborhood Hits	203	Target Neighborhood Hits	161	Shared Neighborhood Hits	63
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.089026 (rank : 240)
Query Neighborhood Hits	203	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF6_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.107376 (rank : 219)
Query Neighborhood Hits	203	Target Neighborhood Hits	178	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.108565 (rank : 217)
Query Neighborhood Hits	203	Target Neighborhood Hits	163	Shared Neighborhood Hits	69
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PJA1_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.060810 (rank : 281)
Query Neighborhood Hits	203	Target Neighborhood Hits	159	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.056969 (rank : 285)
Query Neighborhood Hits	203	Target Neighborhood Hits	145	Shared Neighborhood Hits	37
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PZRN4_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.141524 (rank : 183)
Query Neighborhood Hits	203	Target Neighborhood Hits	438	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

R113A_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.135378 (rank : 193)
Query Neighborhood Hits	203	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.141120 (rank : 185)
Query Neighborhood Hits	203	Target Neighborhood Hits	165	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAD18_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.138365 (rank : 187)
Query Neighborhood Hits	203	Target Neighborhood Hits	284	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.157171 (rank : 177)
Query Neighborhood Hits	203	Target Neighborhood Hits	230	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RBBP6_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.104913 (rank : 221)
Query Neighborhood Hits	203	Target Neighborhood Hits	1135	Shared Neighborhood Hits	102
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.116631 (rank : 208)
Query Neighborhood Hits	203	Target Neighborhood Hits	1014	Shared Neighborhood Hits	98
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RC3H1_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.098877 (rank : 229)
Query Neighborhood Hits	203	Target Neighborhood Hits	433	Shared Neighborhood Hits	81
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.102254 (rank : 227)
Query Neighborhood Hits	203	Target Neighborhood Hits	244	Shared Neighborhood Hits	77
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RFPL1_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.250929 (rank : 117)
Query Neighborhood Hits	203	Target Neighborhood Hits	119	Shared Neighborhood Hits	60
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.257284 (rank : 111)
Query Neighborhood Hits	203	Target Neighborhood Hits	126	Shared Neighborhood Hits	64
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.259068 (rank : 108)
Query Neighborhood Hits	203	Target Neighborhood Hits	134	Shared Neighborhood Hits	65
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFWD2_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.150246 (rank : 180)
Query Neighborhood Hits	203	Target Neighborhood Hits	518	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.149767 (rank : 181)
Query Neighborhood Hits	203	Target Neighborhood Hits	535	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.233106 (rank : 131)
Query Neighborhood Hits	203	Target Neighborhood Hits	219	Shared Neighborhood Hits	97
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.228930 (rank : 135)
Query Neighborhood Hits	203	Target Neighborhood Hits	220	Shared Neighborhood Hits	98
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.214387 (rank : 155)
Query Neighborhood Hits	203	Target Neighborhood Hits	201	Shared Neighborhood Hits	95
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.214481 (rank : 154)
Query Neighborhood Hits	203	Target Neighborhood Hits	199	Shared Neighborhood Hits	95
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN103_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.078311 (rank : 255)
Query Neighborhood Hits	203	Target Neighborhood Hits	153	Shared Neighborhood Hits	50
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.076202 (rank : 257)
Query Neighborhood Hits	203	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN126_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.051273 (rank : 298)
Query Neighborhood Hits	203	Target Neighborhood Hits	143	Shared Neighborhood Hits	35
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN152_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.101050 (rank : 228)
Query Neighborhood Hits	203	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.105886 (rank : 220)
Query Neighborhood Hits	203	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN165_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.051923 (rank : 294)
Query Neighborhood Hits	203	Target Neighborhood Hits	151	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN167_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.066330 (rank : 267)
Query Neighborhood Hits	203	Target Neighborhood Hits	157	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.072356 (rank : 262)
Query Neighborhood Hits	203	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN183_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.192414 (rank : 166)
Query Neighborhood Hits	203	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.164396 (rank : 172)
Query Neighborhood Hits	203	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.253081 (rank : 114)
Query Neighborhood Hits	203	Target Neighborhood Hits	213	Shared Neighborhood Hits	98
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.251301 (rank : 116)
Query Neighborhood Hits	203	Target Neighborhood Hits	211	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF13_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.061467 (rank : 279)
Query Neighborhood Hits	203	Target Neighborhood Hits	147	Shared Neighborhood Hits	38
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.065035 (rank : 272)
Query Neighborhood Hits	203	Target Neighborhood Hits	164	Shared Neighborhood Hits	41
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF26_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.078960 (rank : 254)
Query Neighborhood Hits	203	Target Neighborhood Hits	95	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF32_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.067364 (rank : 266)
Query Neighborhood Hits	203	Target Neighborhood Hits	133	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.060597 (rank : 283)
Query Neighborhood Hits	203	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.109579 (rank : 214)
Query Neighborhood Hits	203	Target Neighborhood Hits	153	Shared Neighborhood Hits	51
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.110917 (rank : 211)
Query Neighborhood Hits	203	Target Neighborhood Hits	160	Shared Neighborhood Hits	52
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF37_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.062926 (rank : 276)
Query Neighborhood Hits	203	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

RNF41_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.203966 (rank : 158)
Query Neighborhood Hits	203	Target Neighborhood Hits	226	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.203938 (rank : 159)
Query Neighborhood Hits	203	Target Neighborhood Hits	224	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.206418 (rank : 157)
Query Neighborhood Hits	203	Target Neighborhood Hits	212	Shared Neighborhood Hits	83
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.200793 (rank : 160)
Query Neighborhood Hits	203	Target Neighborhood Hits	212	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.240623 (rank : 125)
Query Neighborhood Hits	203	Target Neighborhood Hits	206	Shared Neighborhood Hits	95
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.240865 (rank : 124)
Query Neighborhood Hits	203	Target Neighborhood Hits	206	Shared Neighborhood Hits	94
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF8_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.247813 (rank : 119)
Query Neighborhood Hits	203	Target Neighborhood Hits	622	Shared Neighborhood Hits	129
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.257388 (rank : 110)
Query Neighborhood Hits	203	Target Neighborhood Hits	618	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SMRA3_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.160125 (rank : 174)
Query Neighborhood Hits	203	Target Neighborhood Hits	265	Shared Neighborhood Hits	112
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.161597 (rank : 173)
Query Neighborhood Hits	203	Target Neighborhood Hits	267	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SPRY4_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.187544 (rank : 168)
Query Neighborhood Hits	203	Target Neighborhood Hits	79	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.197576 (rank : 161)
Query Neighborhood Hits	203	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TIF1A_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.092776 (rank : 236)
Query Neighborhood Hits	203	Target Neighborhood Hits	327	Shared Neighborhood Hits	77
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.082564 (rank : 248)
Query Neighborhood Hits	203	Target Neighborhood Hits	307	Shared Neighborhood Hits	71
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.128033 (rank : 202)
Query Neighborhood Hits	203	Target Neighborhood Hits	276	Shared Neighborhood Hits	77
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.137142 (rank : 189)
Query Neighborhood Hits	203	Target Neighborhood Hits	410	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.135484 (rank : 192)
Query Neighborhood Hits	203	Target Neighborhood Hits	498	Shared Neighborhood Hits	89
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TOPRS_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.107633 (rank : 218)
Query Neighborhood Hits	203	Target Neighborhood Hits	286	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.109805 (rank : 213)
Query Neighborhood Hits	203	Target Neighborhood Hits	263	Shared Neighborhood Hits	67
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.118116 (rank : 207)
Query Neighborhood Hits	203	Target Neighborhood Hits	402	Shared Neighborhood Hits	84
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.115271 (rank : 209)
Query Neighborhood Hits	203	Target Neighborhood Hits	394	Shared Neighborhood Hits	83
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.109051 (rank : 216)
Query Neighborhood Hits	203	Target Neighborhood Hits	463	Shared Neighborhood Hits	91
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.114570 (rank : 210)
Query Neighborhood Hits	203	Target Neighborhood Hits	476	Shared Neighborhood Hits	96
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.139645 (rank : 186)
Query Neighborhood Hits	203	Target Neighborhood Hits	373	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.097480 (rank : 232)
Query Neighborhood Hits	203	Target Neighborhood Hits	338	Shared Neighborhood Hits	63
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.130637 (rank : 198)
Query Neighborhood Hits	203	Target Neighborhood Hits	396	Shared Neighborhood Hits	84
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.141495 (rank : 184)
Query Neighborhood Hits	203	Target Neighborhood Hits	355	Shared Neighborhood Hits	84
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF7_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.102817 (rank : 226)
Query Neighborhood Hits	203	Target Neighborhood Hits	482	Shared Neighborhood Hits	96
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.104198 (rank : 223)
Query Neighborhood Hits	203	Target Neighborhood Hits	470	Shared Neighborhood Hits	98
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAIP_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.088771 (rank : 241)
Query Neighborhood Hits	203	Target Neighborhood Hits	780	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.079409 (rank : 253)
Query Neighborhood Hits	203	Target Neighborhood Hits	745	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI12_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.379035 (rank : 34)
Query Neighborhood Hits	203	Target Neighborhood Hits	387	Shared Neighborhood Hits	115
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI13_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.355153 (rank : 59)
Query Neighborhood Hits	203	Target Neighborhood Hits	274	Shared Neighborhood Hits	114
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.353671 (rank : 61)
Query Neighborhood Hits	203	Target Neighborhood Hits	282	Shared Neighborhood Hits	112
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI14_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.263869 (rank : 101)
Query Neighborhood Hits	203	Target Neighborhood Hits	143	Shared Neighborhood Hits	64
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.265496 (rank : 99)
Query Neighborhood Hits	203	Target Neighborhood Hits	137	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI16_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.262287 (rank : 104)
Query Neighborhood Hits	203	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.274377 (rank : 94)
Query Neighborhood Hits	203	Target Neighborhood Hits	196	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.217904 (rank : 150)
Query Neighborhood Hits	203	Target Neighborhood Hits	273	Shared Neighborhood Hits	60
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.220649 (rank : 146)
Query Neighborhood Hits	203	Target Neighborhood Hits	306	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI31_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.386448 (rank : 26)
Query Neighborhood Hits	203	Target Neighborhood Hits	299	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI36_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.197560 (rank : 162)
Query Neighborhood Hits	203	Target Neighborhood Hits	282	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI37_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.244474 (rank : 122)
Query Neighborhood Hits	203	Target Neighborhood Hits	307	Shared Neighborhood Hits	100
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.243565 (rank : 123)
Query Neighborhood Hits	203	Target Neighborhood Hits	316	Shared Neighborhood Hits	99
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI42_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.159722 (rank : 175)
Query Neighborhood Hits	203	Target Neighborhood Hits	283	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.165072 (rank : 171)
Query Neighborhood Hits	203	Target Neighborhood Hits	316	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.233741 (rank : 129)
Query Neighborhood Hits	203	Target Neighborhood Hits	393	Shared Neighborhood Hits	68
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.239594 (rank : 126)
Query Neighborhood Hits	203	Target Neighborhood Hits	327	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI45_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.145680 (rank : 182)
Query Neighborhood Hits	203	Target Neighborhood Hits	155	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.137739 (rank : 188)
Query Neighborhood Hits	203	Target Neighborhood Hits	155	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI46_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.225094 (rank : 142)
Query Neighborhood Hits	203	Target Neighborhood Hits	291	Shared Neighborhood Hits	99
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.225652 (rank : 140)
Query Neighborhood Hits	203	Target Neighborhood Hits	287	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI48_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.329448 (rank : 72)
Query Neighborhood Hits	203	Target Neighborhood Hits	192	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI49_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.336224 (rank : 69)
Query Neighborhood Hits	203	Target Neighborhood Hits	199	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI60_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.351542 (rank : 63)
Query Neighborhood Hits	203	Target Neighborhood Hits	240	Shared Neighborhood Hits	106
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI62_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.340379 (rank : 66)
Query Neighborhood Hits	203	Target Neighborhood Hits	584	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.342414 (rank : 65)
Query Neighborhood Hits	203	Target Neighborhood Hits	478	Shared Neighborhood Hits	117
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI68_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.361145 (rank : 55)
Query Neighborhood Hits	203	Target Neighborhood Hits	356	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRIM3_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.294555 (rank : 82)
Query Neighborhood Hits	203	Target Neighborhood Hits	351	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

UB7I3_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.054771 (rank : 287)
Query Neighborhood Hits	203	Target Neighborhood Hits	136	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.063715 (rank : 274)
Query Neighborhood Hits	203	Target Neighborhood Hits	131	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

ZN179_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.318977 (rank : 75)
Query Neighborhood Hits	203	Target Neighborhood Hits	178	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN364_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.053187 (rank : 291)
Query Neighborhood Hits	203	Target Neighborhood Hits	140	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

Hits sorted by NC score

RN169_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	203	Target Neighborhood Hits	203	Shared Neighborhood Hits	203
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN168_HUMAN
NC score	0.520774 (rank : 2)	θ value	3.89403e-11 (rank : 2)
Query Neighborhood Hits	203	Target Neighborhood Hits	370	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
NC score	0.472125 (rank : 3)	θ value	7.59969e-07 (rank : 3)
Query Neighborhood Hits	203	Target Neighborhood Hits	440	Shared Neighborhood Hits	122
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI65_HUMAN
NC score	0.452179 (rank : 4)	θ value	0.00035302 (rank : 9)
Query Neighborhood Hits	203	Target Neighborhood Hits	330	Shared Neighborhood Hits	120
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_MOUSE
NC score	0.431839 (rank : 5)	θ value	0.00390308 (rank : 18)
Query Neighborhood Hits	203	Target Neighborhood Hits	340	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI35_HUMAN
NC score	0.425480 (rank : 6)	θ value	1.87187e-05 (rank : 5)
Query Neighborhood Hits	203	Target Neighborhood Hits	382	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
NC score	0.423235 (rank : 7)	θ value	0.000786445 (rank : 12)
Query Neighborhood Hits	203	Target Neighborhood Hits	465	Shared Neighborhood Hits	129
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI25_MOUSE
NC score	0.416767 (rank : 8)	θ value	0.000461057 (rank : 11)
Query Neighborhood Hits	203	Target Neighborhood Hits	446	Shared Neighborhood Hits	126
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI52_HUMAN
NC score	0.413102 (rank : 9)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	203	Target Neighborhood Hits	213	Shared Neighborhood Hits	102
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI25_HUMAN
NC score	0.409532 (rank : 10)	θ value	0.000158464 (rank : 7)
Query Neighborhood Hits	203	Target Neighborhood Hits	472	Shared Neighborhood Hits	126
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI26_HUMAN
NC score	0.407955 (rank : 11)	θ value	0.0252991 (rank : 29)
Query Neighborhood Hits	203	Target Neighborhood Hits	335	Shared Neighborhood Hits	122
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRIM4_HUMAN
NC score	0.407038 (rank : 12)	θ value	0.000270298 (rank : 8)
Query Neighborhood Hits	203	Target Neighborhood Hits	321	Shared Neighborhood Hits	120
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI26_MOUSE
NC score	0.406197 (rank : 13)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	203	Target Neighborhood Hits	339	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI40_HUMAN
NC score	0.399441 (rank : 14)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	203	Target Neighborhood Hits	279	Shared Neighborhood Hits	111
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM7_HUMAN
NC score	0.398223 (rank : 15)	θ value	9.29e-05 (rank : 6)
Query Neighborhood Hits	203	Target Neighborhood Hits	336	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

RN166_HUMAN
NC score	0.397183 (rank : 16)	θ value	0.00390308 (rank : 16)
Query Neighborhood Hits	203	Target Neighborhood Hits	240	Shared Neighborhood Hits	105
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

ZN313_MOUSE
NC score	0.394982 (rank : 17)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	203	Target Neighborhood Hits	273	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

RN166_MOUSE
NC score	0.393364 (rank : 18)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	203	Target Neighborhood Hits	248	Shared Neighborhood Hits	104
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

ZN313_HUMAN
NC score	0.392047 (rank : 19)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	203	Target Neighborhood Hits	264	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRI10_MOUSE
NC score	0.391606 (rank : 20)	θ value	0.0113563 (rank : 21)
Query Neighborhood Hits	203	Target Neighborhood Hits	285	Shared Neighborhood Hits	114
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

RO52_HUMAN
NC score	0.390536 (rank : 21)	θ value	1.87187e-05 (rank : 4)
Query Neighborhood Hits	203	Target Neighborhood Hits	419	Shared Neighborhood Hits	131
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI10_HUMAN
NC score	0.388873 (rank : 22)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	203	Target Neighborhood Hits	315	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

RO52_MOUSE
NC score	0.387778 (rank : 23)	θ value	0.000461057 (rank : 10)
Query Neighborhood Hits	203	Target Neighborhood Hits	360	Shared Neighborhood Hits	126
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI47_HUMAN
NC score	0.386798 (rank : 24)	θ value	0.0193708 (rank : 28)
Query Neighborhood Hits	203	Target Neighborhood Hits	286	Shared Neighborhood Hits	110
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI60_HUMAN
NC score	0.386720 (rank : 25)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	203	Target Neighborhood Hits	357	Shared Neighborhood Hits	123
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI31_HUMAN
NC score	0.386448 (rank : 26)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	203	Target Neighborhood Hits	299	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI30_MOUSE
NC score	0.386231 (rank : 27)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	203	Target Neighborhood Hits	434	Shared Neighborhood Hits	119
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI11_MOUSE
NC score	0.385346 (rank : 28)	θ value	0.00175202 (rank : 13)
Query Neighborhood Hits	203	Target Neighborhood Hits	329	Shared Neighborhood Hits	119
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRIM7_MOUSE
NC score	0.385331 (rank : 29)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	203	Target Neighborhood Hits	358	Shared Neighborhood Hits	111
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI11_HUMAN
NC score	0.383773 (rank : 30)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	203	Target Neighborhood Hits	316	Shared Neighborhood Hits	118
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI43_HUMAN
NC score	0.380732 (rank : 31)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	203	Target Neighborhood Hits	341	Shared Neighborhood Hits	124
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI47_MOUSE
NC score	0.379266 (rank : 32)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	203	Target Neighborhood Hits	295	Shared Neighborhood Hits	109
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM5_HUMAN
NC score	0.379091 (rank : 33)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	203	Target Neighborhood Hits	424	Shared Neighborhood Hits	121
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI12_MOUSE
NC score	0.379035 (rank : 34)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	203	Target Neighborhood Hits	387	Shared Neighborhood Hits	115
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI39_HUMAN
NC score	0.377850 (rank : 35)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	203	Target Neighborhood Hits	693	Shared Neighborhood Hits	137
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI73_HUMAN
NC score	0.376920 (rank : 36)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	203	Target Neighborhood Hits	258	Shared Neighborhood Hits	114
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI17_HUMAN
NC score	0.376699 (rank : 37)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	203	Target Neighborhood Hits	318	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI39_MOUSE
NC score	0.376519 (rank : 38)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	203	Target Neighborhood Hits	691	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RN125_HUMAN
NC score	0.375659 (rank : 39)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	203	Target Neighborhood Hits	230	Shared Neighborhood Hits	107
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI74_HUMAN
NC score	0.375043 (rank : 40)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	203	Target Neighborhood Hits	249	Shared Neighborhood Hits	112
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM6_MOUSE
NC score	0.373292 (rank : 41)	θ value	0.0148317 (rank : 27)
Query Neighborhood Hits	203	Target Neighborhood Hits	451	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI22_HUMAN
NC score	0.373107 (rank : 42)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	203	Target Neighborhood Hits	396	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRIM8_HUMAN
NC score	0.372961 (rank : 43)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	203	Target Neighborhood Hits	650	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
NC score	0.372068 (rank : 44)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	203	Target Neighborhood Hits	674	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI27_MOUSE
NC score	0.370681 (rank : 45)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	203	Target Neighborhood Hits	261	Shared Neighborhood Hits	116
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI50_HUMAN
NC score	0.368712 (rank : 46)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	203	Target Neighborhood Hits	294	Shared Neighborhood Hits	116
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI27_HUMAN
NC score	0.368666 (rank : 47)	θ value	0.0330416 (rank : 32)
Query Neighborhood Hits	203	Target Neighborhood Hits	273	Shared Neighborhood Hits	115
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRIM6_HUMAN
NC score	0.368596 (rank : 48)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	203	Target Neighborhood Hits	412	Shared Neighborhood Hits	114
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI50_MOUSE
NC score	0.368565 (rank : 49)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	203	Target Neighborhood Hits	326	Shared Neighborhood Hits	123
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI15_HUMAN
NC score	0.368076 (rank : 50)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	203	Target Neighborhood Hits	395	Shared Neighborhood Hits	115
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI68_HUMAN
NC score	0.366041 (rank : 51)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	203	Target Neighborhood Hits	267	Shared Neighborhood Hits	113
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI34_HUMAN
NC score	0.365382 (rank : 52)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	203	Target Neighborhood Hits	416	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI17_MOUSE
NC score	0.364722 (rank : 53)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	203	Target Neighborhood Hits	620	Shared Neighborhood Hits	125
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI59_MOUSE
NC score	0.361851 (rank : 54)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	203	Target Neighborhood Hits	292	Shared Neighborhood Hits	109
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI68_MOUSE
NC score	0.361145 (rank : 55)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	203	Target Neighborhood Hits	356	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI59_HUMAN
NC score	0.359780 (rank : 56)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	203	Target Neighborhood Hits	307	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

RN125_MOUSE
NC score	0.358866 (rank : 57)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	203	Target Neighborhood Hits	220	Shared Neighborhood Hits	108
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

PEX10_HUMAN
NC score	0.357418 (rank : 58)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	203	Target Neighborhood Hits	255	Shared Neighborhood Hits	104
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRI13_HUMAN
NC score	0.355153 (rank : 59)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	203	Target Neighborhood Hits	274	Shared Neighborhood Hits	114
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI41_HUMAN
NC score	0.355004 (rank : 60)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	203	Target Neighborhood Hits	349	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI13_MOUSE
NC score	0.353671 (rank : 61)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	203	Target Neighborhood Hits	282	Shared Neighborhood Hits	112
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI38_HUMAN
NC score	0.352923 (rank : 62)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	203	Target Neighborhood Hits	373	Shared Neighborhood Hits	112
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI60_MOUSE
NC score	0.351542 (rank : 63)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	203	Target Neighborhood Hits	240	Shared Neighborhood Hits	106
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI34_MOUSE
NC score	0.345394 (rank : 64)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	203	Target Neighborhood Hits	332	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI62_MOUSE
NC score	0.342414 (rank : 65)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	203	Target Neighborhood Hits	478	Shared Neighborhood Hits	117
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_HUMAN
NC score	0.340379 (rank : 66)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	203	Target Neighborhood Hits	584	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

BFAR_HUMAN
NC score	0.339199 (rank : 67)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	203	Target Neighborhood Hits	222	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

RNF39_HUMAN
NC score	0.337828 (rank : 68)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	203	Target Neighborhood Hits	200	Shared Neighborhood Hits	99
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI49_HUMAN
NC score	0.336224 (rank : 69)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	203	Target Neighborhood Hits	199	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

BFAR_MOUSE
NC score	0.335806 (rank : 70)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	203	Target Neighborhood Hits	232	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI56_HUMAN
NC score	0.332764 (rank : 71)	θ value	0.0148317 (rank : 26)
Query Neighborhood Hits	203	Target Neighborhood Hits	339	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI48_HUMAN
NC score	0.329448 (rank : 72)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	203	Target Neighborhood Hits	192	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI32_HUMAN
NC score	0.327928 (rank : 73)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	203	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.320554 (rank : 74)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	203	Target Neighborhood Hits	271	Shared Neighborhood Hits	101
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

ZN179_HUMAN
NC score	0.318977 (rank : 75)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	203	Target Neighborhood Hits	178	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI56_MOUSE
NC score	0.309701 (rank : 76)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	203	Target Neighborhood Hits	255	Shared Neighborhood Hits	115
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRIM2_HUMAN
NC score	0.301210 (rank : 77)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	203	Target Neighborhood Hits	330	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.300498 (rank : 78)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	203	Target Neighborhood Hits	331	Shared Neighborhood Hits	109
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI63_MOUSE
NC score	0.299719 (rank : 79)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	203	Target Neighborhood Hits	240	Shared Neighborhood Hits	92
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI55_HUMAN
NC score	0.298606 (rank : 80)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	203	Target Neighborhood Hits	292	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRIM3_HUMAN
NC score	0.297197 (rank : 81)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	203	Target Neighborhood Hits	357	Shared Neighborhood Hits	111
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM3_MOUSE
NC score	0.294555 (rank : 82)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	203	Target Neighborhood Hits	351	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI63_HUMAN
NC score	0.294385 (rank : 83)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	203	Target Neighborhood Hits	298	Shared Neighborhood Hits	98
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

MEFV_HUMAN
NC score	0.286345 (rank : 84)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	203	Target Neighborhood Hits	431	Shared Neighborhood Hits	75
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI54_MOUSE
NC score	0.285150 (rank : 85)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	203	Target Neighborhood Hits	197	Shared Neighborhood Hits	92
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI18_HUMAN
NC score	0.284206 (rank : 86)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	203	Target Neighborhood Hits	307	Shared Neighborhood Hits	106
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
NC score	0.283918 (rank : 87)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	203	Target Neighborhood Hits	292	Shared Neighborhood Hits	106
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI54_HUMAN
NC score	0.283161 (rank : 88)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	203	Target Neighborhood Hits	209	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM1_HUMAN
NC score	0.281148 (rank : 89)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	203	Target Neighborhood Hits	345	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.278586 (rank : 90)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	203	Target Neighborhood Hits	361	Shared Neighborhood Hits	114
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

CBL_HUMAN
NC score	0.277530 (rank : 91)	θ value	0.0113563 (rank : 19)
Query Neighborhood Hits	203	Target Neighborhood Hits	353	Shared Neighborhood Hits	97
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBLB_MOUSE
NC score	0.276358 (rank : 92)	θ value	0.0148317 (rank : 23)
Query Neighborhood Hits	203	Target Neighborhood Hits	277	Shared Neighborhood Hits	94
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.275215 (rank : 93)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	203	Target Neighborhood Hits	261	Shared Neighborhood Hits	92
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

TRI16_MOUSE
NC score	0.274377 (rank : 94)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	203	Target Neighborhood Hits	196	Shared Neighborhood Hits	62
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

CBL_MOUSE
NC score	0.273929 (rank : 95)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	203	Target Neighborhood Hits	426	Shared Neighborhood Hits	100
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBLC_HUMAN
NC score	0.272588 (rank : 96)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	203	Target Neighborhood Hits	173	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

TRAF6_MOUSE
NC score	0.268191 (rank : 97)	θ value	0.0148317 (rank : 25)
Query Neighborhood Hits	203	Target Neighborhood Hits	255	Shared Neighborhood Hits	106
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

CBLC_MOUSE
NC score	0.267191 (rank : 98)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	203	Target Neighborhood Hits	186	Shared Neighborhood Hits	79
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

TRI14_MOUSE
NC score	0.265496 (rank : 99)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	203	Target Neighborhood Hits	137	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRAF6_HUMAN
NC score	0.264272 (rank : 100)	θ value	0.0148317 (rank : 24)
Query Neighborhood Hits	203	Target Neighborhood Hits	267	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI14_HUMAN
NC score	0.263869 (rank : 101)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	203	Target Neighborhood Hits	143	Shared Neighborhood Hits	64
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

BSPRY_MOUSE
NC score	0.263137 (rank : 102)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	203	Target Neighborhood Hits	163	Shared Neighborhood Hits	61
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

MEFV_MOUSE
NC score	0.262478 (rank : 103)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	203	Target Neighborhood Hits	236	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI16_HUMAN
NC score	0.262287 (rank : 104)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	203	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

RAG1_HUMAN
NC score	0.262095 (rank : 105)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	203	Target Neighborhood Hits	203	Shared Neighborhood Hits	86
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
NC score	0.261697 (rank : 106)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	203	Target Neighborhood Hits	189	Shared Neighborhood Hits	90
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

BRCA1_MOUSE
NC score	0.260393 (rank : 107)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	203	Target Neighborhood Hits	436	Shared Neighborhood Hits	117
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RFPL3_HUMAN
NC score	0.259068 (rank : 108)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	203	Target Neighborhood Hits	134	Shared Neighborhood Hits	65
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

BRCA1_HUMAN
NC score	0.257818 (rank : 109)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	203	Target Neighborhood Hits	381	Shared Neighborhood Hits	114
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

RNF8_MOUSE
NC score	0.257388 (rank : 110)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	203	Target Neighborhood Hits	618	Shared Neighborhood Hits	129
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RFPL2_HUMAN
NC score	0.257284 (rank : 111)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	203	Target Neighborhood Hits	126	Shared Neighborhood Hits	64
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

PML_HUMAN
NC score	0.257219 (rank : 112)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	203	Target Neighborhood Hits	248	Shared Neighborhood Hits	92
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

ERMAP_HUMAN
NC score	0.253714 (rank : 113)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	203	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

RN185_HUMAN
NC score	0.253081 (rank : 114)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	203	Target Neighborhood Hits	213	Shared Neighborhood Hits	98
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RKHD1_HUMAN
NC score	0.252818 (rank : 115)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	203	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN185_MOUSE
NC score	0.251301 (rank : 116)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	203	Target Neighborhood Hits	211	Shared Neighborhood Hits	98
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RFPL1_HUMAN
NC score	0.250929 (rank : 117)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	203	Target Neighborhood Hits	119	Shared Neighborhood Hits	60
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

BIRC7_HUMAN
NC score	0.248843 (rank : 118)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	203	Target Neighborhood Hits	185	Shared Neighborhood Hits	98
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

RNF8_HUMAN
NC score	0.247813 (rank : 119)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	203	Target Neighborhood Hits	622	Shared Neighborhood Hits	129
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

BSPRY_HUMAN
NC score	0.245265 (rank : 120)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	203	Target Neighborhood Hits	115	Shared Neighborhood Hits	57
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

PML_MOUSE
NC score	0.244943 (rank : 121)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	203	Target Neighborhood Hits	246	Shared Neighborhood Hits	94
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI37_HUMAN
NC score	0.244474 (rank : 122)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	203	Target Neighborhood Hits	307	Shared Neighborhood Hits	100
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.243565 (rank : 123)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	203	Target Neighborhood Hits	316	Shared Neighborhood Hits	99
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

RNF5_MOUSE
NC score	0.240865 (rank : 124)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	203	Target Neighborhood Hits	206	Shared Neighborhood Hits	94
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF5_HUMAN
NC score	0.240623 (rank : 125)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	203	Target Neighborhood Hits	206	Shared Neighborhood Hits	95
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI44_MOUSE
NC score	0.239594 (rank : 126)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	203	Target Neighborhood Hits	327	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

RN141_HUMAN
NC score	0.237487 (rank : 127)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	203	Target Neighborhood Hits	199	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.237168 (rank : 128)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	203	Target Neighborhood Hits	200	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TRI44_HUMAN
NC score	0.233741 (rank : 129)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	203	Target Neighborhood Hits	393	Shared Neighborhood Hits	68
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

ERMAP_MOUSE
NC score	0.233198 (rank : 130)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	203	Target Neighborhood Hits	231	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

RING1_HUMAN
NC score	0.233106 (rank : 131)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	203	Target Neighborhood Hits	219	Shared Neighborhood Hits	97
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RN146_HUMAN
NC score	0.232276 (rank : 132)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	203	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

CHFR_HUMAN
NC score	0.231123 (rank : 133)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	203	Target Neighborhood Hits	255	Shared Neighborhood Hits	100
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN146_MOUSE
NC score	0.229612 (rank : 134)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	203	Target Neighborhood Hits	161	Shared Neighborhood Hits	88
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RING1_MOUSE
NC score	0.228930 (rank : 135)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	203	Target Neighborhood Hits	220	Shared Neighborhood Hits	98
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

BT1A1_MOUSE
NC score	0.227982 (rank : 136)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	203	Target Neighborhood Hits	252	Shared Neighborhood Hits	48
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

CHFR_MOUSE
NC score	0.226334 (rank : 137)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	203	Target Neighborhood Hits	264	Shared Neighborhood Hits	103
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

UHRF2_MOUSE
NC score	0.225972 (rank : 138)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	203	Target Neighborhood Hits	275	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BT2A2_HUMAN
NC score	0.225711 (rank : 139)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	203	Target Neighborhood Hits	191	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRI46_MOUSE
NC score	0.225652 (rank : 140)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	203	Target Neighborhood Hits	287	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

UHRF2_HUMAN
NC score	0.225609 (rank : 141)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	203	Target Neighborhood Hits	269	Shared Neighborhood Hits	101
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

TRI46_HUMAN
NC score	0.225094 (rank : 142)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	203	Target Neighborhood Hits	291	Shared Neighborhood Hits	99
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

BT1A1_HUMAN
NC score	0.225036 (rank : 143)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	203	Target Neighborhood Hits	322	Shared Neighborhood Hits	49
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A3_HUMAN
NC score	0.223289 (rank : 144)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	203	Target Neighborhood Hits	233	Shared Neighborhood Hits	48
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

TRIM9_HUMAN
NC score	0.220830 (rank : 145)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	203	Target Neighborhood Hits	294	Shared Neighborhood Hits	94
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRI29_MOUSE
NC score	0.220649 (rank : 146)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	203	Target Neighborhood Hits	306	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

BT3A1_HUMAN
NC score	0.220053 (rank : 147)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	203	Target Neighborhood Hits	229	Shared Neighborhood Hits	49
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BTNL9_HUMAN
NC score	0.218683 (rank : 148)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	203	Target Neighborhood Hits	125	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BTNL3_HUMAN
NC score	0.218017 (rank : 149)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	203	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRI29_HUMAN
NC score	0.217904 (rank : 150)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	203	Target Neighborhood Hits	273	Shared Neighborhood Hits	60
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

BT2A3_HUMAN
NC score	0.216441 (rank : 151)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	203	Target Neighborhood Hits	195	Shared Neighborhood Hits	47
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT2A1_HUMAN
NC score	0.216245 (rank : 152)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	203	Target Neighborhood Hits	185	Shared Neighborhood Hits	48
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

TRIM9_MOUSE
NC score	0.215646 (rank : 153)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	203	Target Neighborhood Hits	274	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

RING2_MOUSE
NC score	0.214481 (rank : 154)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	203	Target Neighborhood Hits	199	Shared Neighborhood Hits	95
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.214387 (rank : 155)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	203	Target Neighborhood Hits	201	Shared Neighborhood Hits	95
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

BTNL8_HUMAN
NC score	0.209420 (rank : 156)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	203	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

RNF4_HUMAN
NC score	0.206418 (rank : 157)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	203	Target Neighborhood Hits	212	Shared Neighborhood Hits	83
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF41_HUMAN
NC score	0.203966 (rank : 158)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	203	Target Neighborhood Hits	226	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
NC score	0.203938 (rank : 159)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	203	Target Neighborhood Hits	224	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_MOUSE
NC score	0.200793 (rank : 160)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	203	Target Neighborhood Hits	212	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

SPRY4_MOUSE
NC score	0.197576 (rank : 161)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	203	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI36_HUMAN
NC score	0.197560 (rank : 162)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	203	Target Neighborhood Hits	282	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

DTX3_HUMAN
NC score	0.196209 (rank : 163)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	203	Target Neighborhood Hits	198	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

TRI36_MOUSE
NC score	0.195991 (rank : 164)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	203	Target Neighborhood Hits	266	Shared Neighborhood Hits	93
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

DTX3_MOUSE
NC score	0.193208 (rank : 165)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	203	Target Neighborhood Hits	202	Shared Neighborhood Hits	92
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RN183_HUMAN
NC score	0.192414 (rank : 166)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	203	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

UHRF1_MOUSE
NC score	0.188078 (rank : 167)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	203	Target Neighborhood Hits	278	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

SPRY4_HUMAN
NC score	0.187544 (rank : 168)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	203	Target Neighborhood Hits	79	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

UHRF1_HUMAN
NC score	0.181961 (rank : 169)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	203	Target Neighborhood Hits	272	Shared Neighborhood Hits	100
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

AMFR_MOUSE
NC score	0.166146 (rank : 170)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	203	Target Neighborhood Hits	208	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TRI42_MOUSE
NC score	0.165072 (rank : 171)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	203	Target Neighborhood Hits	316	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

RN183_MOUSE
NC score	0.164396 (rank : 172)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	203	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

SMRA3_MOUSE
NC score	0.161597 (rank : 173)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	203	Target Neighborhood Hits	267	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
NC score	0.160125 (rank : 174)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	203	Target Neighborhood Hits	265	Shared Neighborhood Hits	112
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI42_HUMAN
NC score	0.159722 (rank : 175)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	203	Target Neighborhood Hits	283	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

AMFR2_HUMAN
NC score	0.157336 (rank : 176)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	203	Target Neighborhood Hits	219	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RAD18_MOUSE
NC score	0.157171 (rank : 177)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	203	Target Neighborhood Hits	230	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

PZRN3_MOUSE
NC score	0.153613 (rank : 178)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	203	Target Neighborhood Hits	447	Shared Neighborhood Hits	103
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.152754 (rank : 179)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	203	Target Neighborhood Hits	461	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RFWD2_HUMAN
NC score	0.150246 (rank : 180)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	203	Target Neighborhood Hits	518	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.149767 (rank : 181)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	203	Target Neighborhood Hits	535	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRI45_HUMAN
NC score	0.145680 (rank : 182)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	203	Target Neighborhood Hits	155	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

PZRN4_HUMAN
NC score	0.141524 (rank : 183)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	203	Target Neighborhood Hits	438	Shared Neighborhood Hits	102
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRAF5_MOUSE
NC score	0.141495 (rank : 184)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	203	Target Neighborhood Hits	355	Shared Neighborhood Hits	84
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

R113B_HUMAN
NC score	0.141120 (rank : 185)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	203	Target Neighborhood Hits	165	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TRAF4_HUMAN
NC score	0.139645 (rank : 186)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	203	Target Neighborhood Hits	373	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

RAD18_HUMAN
NC score	0.138365 (rank : 187)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	203	Target Neighborhood Hits	284	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

TRI45_MOUSE
NC score	0.137739 (rank : 188)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	203	Target Neighborhood Hits	155	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TIF1G_HUMAN
NC score	0.137142 (rank : 189)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	203	Target Neighborhood Hits	410	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1B_HUMAN
NC score	0.136570 (rank : 190)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	203	Target Neighborhood Hits	312	Shared Neighborhood Hits	80
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

CM007_MOUSE
NC score	0.135858 (rank : 191)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	203	Target Neighborhood Hits	416	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TIF1G_MOUSE
NC score	0.135484 (rank : 192)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	203	Target Neighborhood Hits	498	Shared Neighborhood Hits	89
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

R113A_HUMAN
NC score	0.135378 (rank : 193)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	203	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

LNX2_MOUSE
NC score	0.131644 (rank : 194)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	203	Target Neighborhood Hits	407	Shared Neighborhood Hits	105
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX2_HUMAN
NC score	0.131427 (rank : 195)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	203	Target Neighborhood Hits	389	Shared Neighborhood Hits	105
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RFFL_HUMAN
NC score	0.131179 (rank : 196)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	203	Target Neighborhood Hits	175	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

LNX1_MOUSE
NC score	0.130656 (rank : 197)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	203	Target Neighborhood Hits	377	Shared Neighborhood Hits	104
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRAF5_HUMAN
NC score	0.130637 (rank : 198)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	203	Target Neighborhood Hits	396	Shared Neighborhood Hits	84
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

RFFL_MOUSE
NC score	0.130448 (rank : 199)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	203	Target Neighborhood Hits	145	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

NHLC1_MOUSE
NC score	0.130182 (rank : 200)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	203	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

LNX1_HUMAN
NC score	0.128413 (rank : 201)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	203	Target Neighborhood Hits	379	Shared Neighborhood Hits	105
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TIF1B_MOUSE
NC score	0.128033 (rank : 202)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	203	Target Neighborhood Hits	276	Shared Neighborhood Hits	77
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

RN123_HUMAN
NC score	0.125610 (rank : 203)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	203	Target Neighborhood Hits	175	Shared Neighborhood Hits	74
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
NC score	0.123919 (rank : 204)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	203	Target Neighborhood Hits	174	Shared Neighborhood Hits	73
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

BIRC8_HUMAN
NC score	0.119744 (rank : 205)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	203	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CM007_HUMAN
NC score	0.119173 (rank : 206)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	203	Target Neighborhood Hits	422	Shared Neighborhood Hits	77
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRAF2_HUMAN
NC score	0.118116 (rank : 207)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	203	Target Neighborhood Hits	402	Shared Neighborhood Hits	84
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

RBBP6_MOUSE
NC score	0.116631 (rank : 208)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	203	Target Neighborhood Hits	1014	Shared Neighborhood Hits	98
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRAF2_MOUSE
NC score	0.115271 (rank : 209)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	203	Target Neighborhood Hits	394	Shared Neighborhood Hits	83
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_MOUSE
NC score	0.114570 (rank : 210)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	203	Target Neighborhood Hits	476	Shared Neighborhood Hits	96
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

RNF34_MOUSE
NC score	0.110917 (rank : 211)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	203	Target Neighborhood Hits	160	Shared Neighborhood Hits	52
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

MGRN1_MOUSE
NC score	0.110525 (rank : 212)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	203	Target Neighborhood Hits	149	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

TOPRS_MOUSE
NC score	0.109805 (rank : 213)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	203	Target Neighborhood Hits	263	Shared Neighborhood Hits	67
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RNF34_HUMAN
NC score	0.109579 (rank : 214)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	203	Target Neighborhood Hits	153	Shared Neighborhood Hits	51
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

MGRN1_HUMAN
NC score	0.109552 (rank : 215)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	203	Target Neighborhood Hits	192	Shared Neighborhood Hits	66
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

TRAF3_HUMAN
NC score	0.109051 (rank : 216)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	203	Target Neighborhood Hits	463	Shared Neighborhood Hits	91
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

PCGF6_MOUSE
NC score	0.108565 (rank : 217)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	203	Target Neighborhood Hits	163	Shared Neighborhood Hits	69
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TOPRS_HUMAN
NC score	0.107633 (rank : 218)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	203	Target Neighborhood Hits	286	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

PCGF6_HUMAN
NC score	0.107376 (rank : 219)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	203	Target Neighborhood Hits	178	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RN152_MOUSE
NC score	0.105886 (rank : 220)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	203	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RBBP6_HUMAN
NC score	0.104913 (rank : 221)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	203	Target Neighborhood Hits	1135	Shared Neighborhood Hits	102
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

NEURL_MOUSE
NC score	0.104555 (rank : 222)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	203	Target Neighborhood Hits	106	Shared Neighborhood Hits	42
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

TRAF7_MOUSE
NC score	0.104198 (rank : 223)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	203	Target Neighborhood Hits	470	Shared Neighborhood Hits	98
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

NEUL1_HUMAN
NC score	0.104176 (rank : 224)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	203	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NHLC1_HUMAN
NC score	0.103258 (rank : 225)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	203	Target Neighborhood Hits	91	Shared Neighborhood Hits	51
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRAF7_HUMAN
NC score	0.102817 (rank : 226)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	203	Target Neighborhood Hits	482	Shared Neighborhood Hits	96
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

RC3H1_MOUSE
NC score	0.102254 (rank : 227)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	203	Target Neighborhood Hits	244	Shared Neighborhood Hits	77
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RN152_HUMAN
NC score	0.101050 (rank : 228)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	203	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RC3H1_HUMAN
NC score	0.098877 (rank : 229)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	203	Target Neighborhood Hits	433	Shared Neighborhood Hits	81
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

BIRC3_HUMAN
NC score	0.097753 (rank : 230)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	203	Target Neighborhood Hits	133	Shared Neighborhood Hits	64
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

MAT1_HUMAN
NC score	0.097724 (rank : 231)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	203	Target Neighborhood Hits	179	Shared Neighborhood Hits	39
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

TRAF4_MOUSE
NC score	0.097480 (rank : 232)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	203	Target Neighborhood Hits	338	Shared Neighborhood Hits	63
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

DTX3L_HUMAN
NC score	0.096044 (rank : 233)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	203	Target Neighborhood Hits	187	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RNF37_MOUSE
NC score	0.095628 (rank : 234)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	203	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

ZRAB2_HUMAN
NC score	0.093769 (rank : 235)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	203	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

TIF1A_HUMAN
NC score	0.092776 (rank : 236)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	203	Target Neighborhood Hits	327	Shared Neighborhood Hits	77
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

BIRC3_MOUSE
NC score	0.092118 (rank : 237)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	203	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC2_HUMAN
NC score	0.091040 (rank : 238)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	203	Target Neighborhood Hits	142	Shared Neighborhood Hits	66
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

PCGF4_HUMAN
NC score	0.090355 (rank : 239)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	203	Target Neighborhood Hits	161	Shared Neighborhood Hits	63
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.089026 (rank : 240)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	203	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

TRAIP_HUMAN
NC score	0.088771 (rank : 241)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	203	Target Neighborhood Hits	780	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

BIRC2_MOUSE
NC score	0.087660 (rank : 242)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	203	Target Neighborhood Hits	137	Shared Neighborhood Hits	59
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

PCGF2_HUMAN
NC score	0.086643 (rank : 243)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	203	Target Neighborhood Hits	222	Shared Neighborhood Hits	60
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.086616 (rank : 244)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	203	Target Neighborhood Hits	213	Shared Neighborhood Hits	60
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

MAT1_MOUSE
NC score	0.086387 (rank : 245)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	203	Target Neighborhood Hits	217	Shared Neighborhood Hits	40
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

ASPX_MOUSE
NC score	0.084760 (rank : 246)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	203	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

MYLIP_HUMAN
NC score	0.084552 (rank : 247)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	203	Target Neighborhood Hits	162	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

TIF1A_MOUSE
NC score	0.082564 (rank : 248)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	203	Target Neighborhood Hits	307	Shared Neighborhood Hits	71
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

BARD1_MOUSE
NC score	0.082480 (rank : 249)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	203	Target Neighborhood Hits	411	Shared Neighborhood Hits	64
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

SPAT2_HUMAN
NC score	0.081604 (rank : 250)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	203	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

BRE1B_MOUSE
NC score	0.080886 (rank : 251)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	203	Target Neighborhood Hits	970	Shared Neighborhood Hits	99
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.080838 (rank : 252)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	203	Target Neighborhood Hits	1040	Shared Neighborhood Hits	103
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

TRAIP_MOUSE
NC score	0.079409 (rank : 253)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	203	Target Neighborhood Hits	745	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

RNF26_HUMAN
NC score	0.078960 (rank : 254)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	203	Target Neighborhood Hits	95	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RN103_HUMAN
NC score	0.078311 (rank : 255)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	203	Target Neighborhood Hits	153	Shared Neighborhood Hits	50
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

AL2S4_HUMAN
NC score	0.077492 (rank : 256)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	203	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q45, Q53TS9, Q53TT2, Q7Z3B6, Q8IZ18, Q8NBF8, Q96CY1	Gene names	ALS2CR4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein.

RN103_MOUSE
NC score	0.076202 (rank : 257)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	203	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

ARD1_MOUSE
NC score	0.075097 (rank : 258)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	203	Target Neighborhood Hits	573	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

MNAB_HUMAN
NC score	0.074078 (rank : 259)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	203	Target Neighborhood Hits	196	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

BARD1_HUMAN
NC score	0.073224 (rank : 260)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	203	Target Neighborhood Hits	427	Shared Neighborhood Hits	60
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MNAB_MOUSE
NC score	0.072618 (rank : 261)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	203	Target Neighborhood Hits	231	Shared Neighborhood Hits	69
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RN167_MOUSE
NC score	0.072356 (rank : 262)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	203	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

ARD1_HUMAN
NC score	0.070574 (rank : 263)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	203	Target Neighborhood Hits	621	Shared Neighborhood Hits	57
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

CT077_MOUSE
NC score	0.069793 (rank : 264)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	203	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CSU0, Q3U8H1, Q3UGH1, Q3USX3, Q6GTJ6	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf77 homolog.

CNOT4_HUMAN
NC score	0.067783 (rank : 265)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	203	Target Neighborhood Hits	207	Shared Neighborhood Hits	34
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RNF32_HUMAN
NC score	0.067364 (rank : 266)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	203	Target Neighborhood Hits	133	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RN167_HUMAN
NC score	0.066330 (rank : 267)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	203	Target Neighborhood Hits	157	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

BRE1A_HUMAN
NC score	0.066188 (rank : 268)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	203	Target Neighborhood Hits	1071	Shared Neighborhood Hits	100
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CT077_HUMAN
NC score	0.065923 (rank : 269)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	203	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

BRE1A_MOUSE
NC score	0.065891 (rank : 270)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	203	Target Neighborhood Hits	1025	Shared Neighborhood Hits	99
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CNOT4_MOUSE
NC score	0.065540 (rank : 271)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	203	Target Neighborhood Hits	277	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RNF13_MOUSE
NC score	0.065035 (rank : 272)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	203	Target Neighborhood Hits	164	Shared Neighborhood Hits	41
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

FA50A_HUMAN
NC score	0.064017 (rank : 273)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	203	Target Neighborhood Hits	264	Shared Neighborhood Hits	17
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

UB7I3_MOUSE
NC score	0.063715 (rank : 274)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	203	Target Neighborhood Hits	131	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

BIRC4_HUMAN
NC score	0.063144 (rank : 275)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	203	Target Neighborhood Hits	89	Shared Neighborhood Hits	40
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

RNF37_HUMAN
NC score	0.062926 (rank : 276)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	203	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

BIRC4_MOUSE
NC score	0.062470 (rank : 277)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	203	Target Neighborhood Hits	89	Shared Neighborhood Hits	40
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BRAP_HUMAN
NC score	0.061739 (rank : 278)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	203	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RNF13_HUMAN
NC score	0.061467 (rank : 279)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	203	Target Neighborhood Hits	147	Shared Neighborhood Hits	38
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

ASXL1_HUMAN
NC score	0.060985 (rank : 280)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	203	Target Neighborhood Hits	260	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

PJA1_HUMAN
NC score	0.060810 (rank : 281)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	203	Target Neighborhood Hits	159	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

MYLIP_MOUSE
NC score	0.060752 (rank : 282)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	203	Target Neighborhood Hits	139	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RNF32_MOUSE
NC score	0.060597 (rank : 283)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	203	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

FA50A_MOUSE
NC score	0.059150 (rank : 284)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	203	Target Neighborhood Hits	293	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WV03, Q9D866	Gene names	Fam50a, D0HXS9928E, Xap5
Domain Architecture
Description	Protein FAM50A (XAP-5 protein).

PJA1_MOUSE
NC score	0.056969 (rank : 285)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	203	Target Neighborhood Hits	145	Shared Neighborhood Hits	37
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

SDPR_MOUSE
NC score	0.055114 (rank : 286)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	203	Target Neighborhood Hits	485	Shared Neighborhood Hits	26
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

UB7I3_HUMAN
NC score	0.054771 (rank : 287)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	203	Target Neighborhood Hits	136	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

BRAP_MOUSE
NC score	0.053824 (rank : 288)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	203	Target Neighborhood Hits	409	Shared Neighborhood Hits	42
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

FA50B_MOUSE
NC score	0.053805 (rank : 289)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	203	Target Neighborhood Hits	186	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WTJ8, Q80X84, Q9D993	Gene names	Fam50b, D0H6S2654E, X5l
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

IWS1_HUMAN
NC score	0.053207 (rank : 290)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	203	Target Neighborhood Hits	1241	Shared Neighborhood Hits	38
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ZN364_HUMAN
NC score	0.053187 (rank : 291)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	203	Target Neighborhood Hits	140	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

IWS1_MOUSE
NC score	0.052525 (rank : 292)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	203	Target Neighborhood Hits	1258	Shared Neighborhood Hits	38
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AKA12_HUMAN
NC score	0.052457 (rank : 293)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	203	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

RN165_HUMAN
NC score	0.051923 (rank : 294)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	203	Target Neighborhood Hits	151	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

FSD1L_MOUSE
NC score	0.051619 (rank : 295)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	203	Target Neighborhood Hits	78	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

AFF4_MOUSE
NC score	0.051605 (rank : 296)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	203	Target Neighborhood Hits	581	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

LRSM1_MOUSE
NC score	0.051526 (rank : 297)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	203	Target Neighborhood Hits	874	Shared Neighborhood Hits	74
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

RN126_MOUSE
NC score	0.051273 (rank : 298)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	203	Target Neighborhood Hits	143	Shared Neighborhood Hits	35
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

LRSM1_HUMAN
NC score	0.050063 (rank : 299)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	203	Target Neighborhood Hits	1078	Shared Neighborhood Hits	81
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

BPTF_HUMAN
NC score	0.046126 (rank : 300)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	203	Target Neighborhood Hits	786	Shared Neighborhood Hits	28
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CPLX4_HUMAN
NC score	0.045471 (rank : 301)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	203	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z7G2	Gene names	CPLX4
Domain Architecture	No domain graphic available
Description	Complexin-4 (Complexin IV) (CPX IV).

PCLO_HUMAN
NC score	0.043002 (rank : 302)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	203	Target Neighborhood Hits	2046	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

EXO1_HUMAN
NC score	0.041703 (rank : 303)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	203	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

MLL2_HUMAN
NC score	0.041389 (rank : 304)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	203	Target Neighborhood Hits	1788	Shared Neighborhood Hits	56
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SYCP1_MOUSE
NC score	0.041036 (rank : 305)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	203	Target Neighborhood Hits	1456	Shared Neighborhood Hits	64
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

PCLO_MOUSE
NC score	0.039571 (rank : 306)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	203	Target Neighborhood Hits	2275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MD1L1_HUMAN
NC score	0.038395 (rank : 307)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	203	Target Neighborhood Hits	893	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

DUS1L_HUMAN
NC score	0.038225 (rank : 308)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	203	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1R4, Q96AI3	Gene names	DUS1L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

TRHY_HUMAN
NC score	0.038074 (rank : 309)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	203	Target Neighborhood Hits	1385	Shared Neighborhood Hits	55
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CNTRB_HUMAN
NC score	0.037212 (rank : 310)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	203	Target Neighborhood Hits	690	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CNTRB_MOUSE
NC score	0.036303 (rank : 311)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	203	Target Neighborhood Hits	1029	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CROCC_MOUSE
NC score	0.035078 (rank : 312)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	203	Target Neighborhood Hits	1460	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CENPE_HUMAN
NC score	0.035025 (rank : 313)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	203	Target Neighborhood Hits	2060	Shared Neighborhood Hits	79
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GON4L_MOUSE
NC score	0.034361 (rank : 314)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	203	Target Neighborhood Hits	455	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

BPAEA_MOUSE
NC score	0.034167 (rank : 315)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	203	Target Neighborhood Hits	1480	Shared Neighborhood Hits	62
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ZN318_MOUSE
NC score	0.031723 (rank : 316)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	203	Target Neighborhood Hits	642	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

TCAL5_HUMAN
NC score	0.031647 (rank : 317)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	203	Target Neighborhood Hits	806	Shared Neighborhood Hits	26
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

SYCP1_HUMAN
NC score	0.031452 (rank : 318)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	203	Target Neighborhood Hits	1313	Shared Neighborhood Hits	50
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

RAI14_MOUSE
NC score	0.031027 (rank : 319)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	203	Target Neighborhood Hits	1505	Shared Neighborhood Hits	52
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RPTOR_MOUSE
NC score	0.030603 (rank : 320)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	203	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4Q0, Q8C9W9, Q8CBY4, Q8CDY8, Q9D4H3	Gene names	Raptor
Domain Architecture
Description	Regulatory-associated protein of mTOR (Raptor) (P150 target of rapamycin (TOR)-scaffold protein).

MD1L1_MOUSE
NC score	0.030523 (rank : 321)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	203	Target Neighborhood Hits	1001	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

DIDO1_HUMAN
NC score	0.030005 (rank : 322)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	203	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

BPA1_MOUSE
NC score	0.029528 (rank : 323)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	203	Target Neighborhood Hits	1477	Shared Neighborhood Hits	50
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DUS1L_MOUSE
NC score	0.028775 (rank : 324)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	203	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2P3, Q8VCN7, Q9D124	Gene names	Dus1l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

CCD93_MOUSE
NC score	0.028648 (rank : 325)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	203	Target Neighborhood Hits	362	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

MY18A_MOUSE
NC score	0.026920 (rank : 326)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	203	Target Neighborhood Hits	1989	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

EHMT2_MOUSE
NC score	0.025630 (rank : 327)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	203	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

DAB2P_MOUSE
NC score	0.025404 (rank : 328)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	203	Target Neighborhood Hits	284	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

TSKS_MOUSE
NC score	0.024723 (rank : 329)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	203	Target Neighborhood Hits	188	Shared Neighborhood Hits	12
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

FANCF_HUMAN
NC score	0.024657 (rank : 330)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	203	Target Neighborhood Hits	2	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPI8, Q52LM0	Gene names	FANCF
Domain Architecture	No domain graphic available
Description	Fanconi anemia group F protein (Protein FACF).

E41L2_HUMAN
NC score	0.024493 (rank : 331)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	203	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

SASH1_MOUSE
NC score	0.024238 (rank : 332)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	203	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

MCES_MOUSE
NC score	0.023688 (rank : 333)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	203	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0L8, Q3V3U9, Q6ZQC6, Q9D5F1	Gene names	Rnmt, Kiaa0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase).

Z3H7A_HUMAN
NC score	0.023354 (rank : 334)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	203	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

CLIC6_HUMAN
NC score	0.023172 (rank : 335)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	203	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CECR2_HUMAN
NC score	0.023011 (rank : 336)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	203	Target Neighborhood Hits	543	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

NPBL_MOUSE
NC score	0.021596 (rank : 337)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	203	Target Neighborhood Hits	1041	Shared Neighborhood Hits	25
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TXLNA_HUMAN
NC score	0.020849 (rank : 338)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	203	Target Neighborhood Hits	982	Shared Neighborhood Hits	28
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

EGFL7_HUMAN
NC score	0.020237 (rank : 339)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	203	Target Neighborhood Hits	325	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

MYH7_HUMAN
NC score	0.017995 (rank : 340)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	203	Target Neighborhood Hits	1559	Shared Neighborhood Hits	55
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PI3R4_MOUSE
NC score	0.017931 (rank : 341)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	203	Target Neighborhood Hits	535	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

PDZD2_HUMAN
NC score	0.017794 (rank : 342)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	203	Target Neighborhood Hits	772	Shared Neighborhood Hits	24
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PI3R4_HUMAN
NC score	0.016859 (rank : 343)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	203	Target Neighborhood Hits	534	Shared Neighborhood Hits	7
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

FX4L1_HUMAN
NC score	0.016720 (rank : 344)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	203	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NU39	Gene names	FOXD4L1
Domain Architecture
Description	Forkhead box protein D4-like 1.

LMNB1_MOUSE
NC score	0.016321 (rank : 345)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	203	Target Neighborhood Hits	719	Shared Neighborhood Hits	30
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

SMCA4_HUMAN
NC score	0.015137 (rank : 346)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	203	Target Neighborhood Hits	597	Shared Neighborhood Hits	24
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMCA2_HUMAN
NC score	0.014385 (rank : 347)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	203	Target Neighborhood Hits	503	Shared Neighborhood Hits	25
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

ADA15_MOUSE
NC score	0.014266 (rank : 348)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	203	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA15_HUMAN
NC score	0.014113 (rank : 349)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	203	Target Neighborhood Hits	288	Shared Neighborhood Hits	6
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

DDX54_HUMAN
NC score	0.013523 (rank : 350)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	203	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

SP100_HUMAN
NC score	0.013306 (rank : 351)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	203	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

NKTR_HUMAN
NC score	0.011343 (rank : 352)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	203	Target Neighborhood Hits	658	Shared Neighborhood Hits	18
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

DDX27_MOUSE
NC score	0.010889 (rank : 353)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	203	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

ITB6_MOUSE
NC score	0.010170 (rank : 354)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	203	Target Neighborhood Hits	341	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

CAC1G_HUMAN
NC score	0.008502 (rank : 355)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	203	Target Neighborhood Hits	587	Shared Neighborhood Hits	13
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

FRAS1_HUMAN
NC score	0.007442 (rank : 356)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	203	Target Neighborhood Hits	759	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TBX2_HUMAN
NC score	0.006782 (rank : 357)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	203	Target Neighborhood Hits	195	Shared Neighborhood Hits	6
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

PHLPP_HUMAN
NC score	0.004994 (rank : 358)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	203	Target Neighborhood Hits	604	Shared Neighborhood Hits	13
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

VASN_HUMAN
NC score	0.003110 (rank : 359)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	203	Target Neighborhood Hits	449	Shared Neighborhood Hits	5
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

MARK2_HUMAN
NC score	0.002563 (rank : 360)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	203	Target Neighborhood Hits	1056	Shared Neighborhood Hits	9
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MAST4_HUMAN
NC score	0.001533 (rank : 361)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	203	Target Neighborhood Hits	1804	Shared Neighborhood Hits	33
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CELR3_HUMAN
NC score	-0.001081 (rank : 362)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	203	Target Neighborhood Hits	680	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

ZSCA4_HUMAN
NC score	-0.001752 (rank : 363)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	203	Target Neighborhood Hits	713	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NAM6	Gene names	ZSCAN4, ZNF494
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494).