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Network neighborhood for query Sequence : DDX54_HUMAN

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DDX54_HUMAN
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX54_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	170	Target Neighborhood Hits	170	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX54_MOUSE
θ value	0 (rank : 2)	NC score	0.995115 (rank : 2)
Query Neighborhood Hits	170	Target Neighborhood Hits	124	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX49_MOUSE
θ value	1.45929e-58 (rank : 3)	NC score	0.967349 (rank : 4)
Query Neighborhood Hits	170	Target Neighborhood Hits	119	Shared Neighborhood Hits	86
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_HUMAN
θ value	2.10721e-57 (rank : 4)	NC score	0.964015 (rank : 6)
Query Neighborhood Hits	170	Target Neighborhood Hits	223	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX46_HUMAN
θ value	2.32979e-56 (rank : 5)	NC score	0.942543 (rank : 49)
Query Neighborhood Hits	170	Target Neighborhood Hits	357	Shared Neighborhood Hits	102
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	2.32979e-56 (rank : 6)	NC score	0.940439 (rank : 50)
Query Neighborhood Hits	170	Target Neighborhood Hits	358	Shared Neighborhood Hits	102
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX27_MOUSE
θ value	5.19021e-56 (rank : 7)	NC score	0.961595 (rank : 7)
Query Neighborhood Hits	170	Target Neighborhood Hits	174	Shared Neighborhood Hits	87
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
θ value	4.39379e-55 (rank : 8)	NC score	0.960058 (rank : 10)
Query Neighborhood Hits	170	Target Neighborhood Hits	197	Shared Neighborhood Hits	89
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX47_HUMAN
θ value	4.85792e-54 (rank : 9)	NC score	0.967147 (rank : 5)
Query Neighborhood Hits	170	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	4.85792e-54 (rank : 10)	NC score	0.967656 (rank : 3)
Query Neighborhood Hits	170	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX23_HUMAN
θ value	7.01481e-53 (rank : 11)	NC score	0.932224 (rank : 54)
Query Neighborhood Hits	170	Target Neighborhood Hits	486	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX53_HUMAN
θ value	5.55816e-50 (rank : 12)	NC score	0.954551 (rank : 17)
Query Neighborhood Hits	170	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX48_HUMAN
θ value	1.61718e-49 (rank : 13)	NC score	0.953320 (rank : 20)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	2.1121e-49 (rank : 14)	NC score	0.953153 (rank : 21)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX6_HUMAN
θ value	4.70527e-49 (rank : 15)	NC score	0.961150 (rank : 8)
Query Neighborhood Hits	170	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	4.70527e-49 (rank : 16)	NC score	0.960976 (rank : 9)
Query Neighborhood Hits	170	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX4_HUMAN
θ value	1.788e-48 (rank : 17)	NC score	0.954027 (rank : 18)
Query Neighborhood Hits	170	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	1.51363e-47 (rank : 18)	NC score	0.954895 (rank : 14)
Query Neighborhood Hits	170	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX10_HUMAN
θ value	1.97686e-47 (rank : 19)	NC score	0.947405 (rank : 38)
Query Neighborhood Hits	170	Target Neighborhood Hits	210	Shared Neighborhood Hits	86
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	2.58187e-47 (rank : 20)	NC score	0.947342 (rank : 40)
Query Neighborhood Hits	170	Target Neighborhood Hits	233	Shared Neighborhood Hits	91
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX3X_HUMAN
θ value	2.58187e-47 (rank : 21)	NC score	0.944661 (rank : 46)
Query Neighborhood Hits	170	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	4.40402e-47 (rank : 22)	NC score	0.944322 (rank : 47)
Query Neighborhood Hits	170	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
θ value	7.51208e-47 (rank : 23)	NC score	0.944925 (rank : 45)
Query Neighborhood Hits	170	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_MOUSE
θ value	1.28137e-46 (rank : 24)	NC score	0.945112 (rank : 44)
Query Neighborhood Hits	170	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX43_HUMAN
θ value	1.28137e-46 (rank : 25)	NC score	0.956833 (rank : 12)
Query Neighborhood Hits	170	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX5_MOUSE
θ value	6.35935e-46 (rank : 26)	NC score	0.949923 (rank : 28)
Query Neighborhood Hits	170	Target Neighborhood Hits	101	Shared Neighborhood Hits	85
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX17_HUMAN
θ value	8.30557e-46 (rank : 27)	NC score	0.952735 (rank : 23)
Query Neighborhood Hits	170	Target Neighborhood Hits	104	Shared Neighborhood Hits	85
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	8.30557e-46 (rank : 28)	NC score	0.952870 (rank : 22)
Query Neighborhood Hits	170	Target Neighborhood Hits	105	Shared Neighborhood Hits	85
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX41_HUMAN
θ value	3.15612e-45 (rank : 29)	NC score	0.956946 (rank : 11)
Query Neighborhood Hits	170	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	3.15612e-45 (rank : 30)	NC score	0.956460 (rank : 13)
Query Neighborhood Hits	170	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX5_HUMAN
θ value	3.15612e-45 (rank : 31)	NC score	0.949885 (rank : 29)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX3Y_HUMAN
θ value	4.122e-45 (rank : 32)	NC score	0.942816 (rank : 48)
Query Neighborhood Hits	170	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX18_MOUSE
θ value	2.04573e-44 (rank : 33)	NC score	0.953513 (rank : 19)
Query Neighborhood Hits	170	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

IF4A1_HUMAN
θ value	4.55743e-44 (rank : 34)	NC score	0.949672 (rank : 30)
Query Neighborhood Hits	170	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	4.55743e-44 (rank : 35)	NC score	0.949672 (rank : 31)
Query Neighborhood Hits	170	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	2.26182e-43 (rank : 36)	NC score	0.949125 (rank : 33)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	2.26182e-43 (rank : 37)	NC score	0.949125 (rank : 34)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX18_HUMAN
θ value	1.12253e-42 (rank : 38)	NC score	0.952174 (rank : 24)
Query Neighborhood Hits	170	Target Neighborhood Hits	124	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX52_HUMAN
θ value	5.21438e-40 (rank : 39)	NC score	0.954803 (rank : 16)
Query Neighborhood Hits	170	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX31_HUMAN
θ value	6.81017e-40 (rank : 40)	NC score	0.948321 (rank : 36)
Query Neighborhood Hits	170	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX52_MOUSE
θ value	6.81017e-40 (rank : 41)	NC score	0.954827 (rank : 15)
Query Neighborhood Hits	170	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX55_MOUSE
θ value	5.76516e-39 (rank : 42)	NC score	0.952011 (rank : 25)
Query Neighborhood Hits	170	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

UAP56_HUMAN
θ value	5.76516e-39 (rank : 43)	NC score	0.947082 (rank : 41)
Query Neighborhood Hits	170	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	5.76516e-39 (rank : 44)	NC score	0.947002 (rank : 43)
Query Neighborhood Hits	170	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX55_HUMAN
θ value	7.52953e-39 (rank : 45)	NC score	0.951200 (rank : 26)
Query Neighborhood Hits	170	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX39_MOUSE
θ value	3.73686e-38 (rank : 46)	NC score	0.947348 (rank : 39)
Query Neighborhood Hits	170	Target Neighborhood Hits	97	Shared Neighborhood Hits	84
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX39_HUMAN
θ value	1.85459e-37 (rank : 47)	NC score	0.947506 (rank : 37)
Query Neighborhood Hits	170	Target Neighborhood Hits	94	Shared Neighborhood Hits	85
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX21_HUMAN
θ value	7.04741e-37 (rank : 48)	NC score	0.926269 (rank : 61)
Query Neighborhood Hits	170	Target Neighborhood Hits	308	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX50_MOUSE
θ value	7.04741e-37 (rank : 49)	NC score	0.938612 (rank : 51)
Query Neighborhood Hits	170	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
θ value	1.57e-36 (rank : 50)	NC score	0.938514 (rank : 52)
Query Neighborhood Hits	170	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX21_MOUSE
θ value	1.01765e-35 (rank : 51)	NC score	0.918506 (rank : 65)
Query Neighborhood Hits	170	Target Neighborhood Hits	350	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX28_MOUSE
θ value	3.86705e-35 (rank : 52)	NC score	0.951166 (rank : 27)
Query Neighborhood Hits	170	Target Neighborhood Hits	112	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX56_MOUSE
θ value	2.50655e-34 (rank : 53)	NC score	0.949011 (rank : 35)
Query Neighborhood Hits	170	Target Neighborhood Hits	87	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
θ value	1.6247e-33 (rank : 54)	NC score	0.949258 (rank : 32)
Query Neighborhood Hits	170	Target Neighborhood Hits	77	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX25_HUMAN
θ value	4.72714e-33 (rank : 55)	NC score	0.928588 (rank : 58)
Query Neighborhood Hits	170	Target Neighborhood Hits	93	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX20_HUMAN
θ value	1.79631e-32 (rank : 56)	NC score	0.935633 (rank : 53)
Query Neighborhood Hits	170	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	2.34606e-32 (rank : 57)	NC score	0.932194 (rank : 55)
Query Neighborhood Hits	170	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX25_MOUSE
θ value	3.06405e-32 (rank : 58)	NC score	0.927428 (rank : 60)
Query Neighborhood Hits	170	Target Neighborhood Hits	98	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_HUMAN
θ value	8.91499e-32 (rank : 59)	NC score	0.926148 (rank : 62)
Query Neighborhood Hits	170	Target Neighborhood Hits	107	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	1.16434e-31 (rank : 60)	NC score	0.925540 (rank : 63)
Query Neighborhood Hits	170	Target Neighborhood Hits	105	Shared Neighborhood Hits	81
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	1.16434e-31 (rank : 61)	NC score	0.925442 (rank : 64)
Query Neighborhood Hits	170	Target Neighborhood Hits	109	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX24_MOUSE
θ value	3.74554e-30 (rank : 62)	NC score	0.930346 (rank : 56)
Query Neighborhood Hits	170	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
θ value	8.3442e-30 (rank : 63)	NC score	0.927540 (rank : 59)
Query Neighborhood Hits	170	Target Neighborhood Hits	190	Shared Neighborhood Hits	84
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX51_MOUSE
θ value	1.08979e-29 (rank : 64)	NC score	0.928695 (rank : 57)
Query Neighborhood Hits	170	Target Neighborhood Hits	130	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX28_HUMAN
θ value	1.4233e-29 (rank : 65)	NC score	0.947031 (rank : 42)
Query Neighborhood Hits	170	Target Neighborhood Hits	103	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX51_HUMAN
θ value	3.28125e-26 (rank : 66)	NC score	0.911196 (rank : 66)
Query Neighborhood Hits	170	Target Neighborhood Hits	332	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX1_MOUSE
θ value	3.17815e-21 (rank : 67)	NC score	0.884089 (rank : 67)
Query Neighborhood Hits	170	Target Neighborhood Hits	112	Shared Neighborhood Hits	82
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
θ value	7.0802e-21 (rank : 68)	NC score	0.882427 (rank : 68)
Query Neighborhood Hits	170	Target Neighborhood Hits	110	Shared Neighborhood Hits	82
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

WRN_HUMAN
θ value	6.43352e-06 (rank : 69)	NC score	0.470921 (rank : 73)
Query Neighborhood Hits	170	Target Neighborhood Hits	132	Shared Neighborhood Hits	82
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

BLM_MOUSE
θ value	9.29e-05 (rank : 70)	NC score	0.492944 (rank : 71)
Query Neighborhood Hits	170	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RPTN_MOUSE
θ value	0.00020696 (rank : 71)	NC score	0.040703 (rank : 100)
Query Neighborhood Hits	170	Target Neighborhood Hits	650	Shared Neighborhood Hits	51
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

BLM_HUMAN
θ value	0.000461057 (rank : 72)	NC score	0.479116 (rank : 72)
Query Neighborhood Hits	170	Target Neighborhood Hits	148	Shared Neighborhood Hits	75
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_MOUSE
θ value	0.000602161 (rank : 73)	NC score	0.435904 (rank : 75)
Query Neighborhood Hits	170	Target Neighborhood Hits	295	Shared Neighborhood Hits	82
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

SFRS4_HUMAN
θ value	0.00175202 (rank : 74)	NC score	0.024765 (rank : 114)
Query Neighborhood Hits	170	Target Neighborhood Hits	384	Shared Neighborhood Hits	15
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SFRS4_MOUSE
θ value	0.00298849 (rank : 75)	NC score	0.024023 (rank : 116)
Query Neighborhood Hits	170	Target Neighborhood Hits	406	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TMAP1_HUMAN
θ value	0.00390308 (rank : 76)	NC score	0.052233 (rank : 98)
Query Neighborhood Hits	170	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

RECQ4_MOUSE
θ value	0.00869519 (rank : 77)	NC score	0.517358 (rank : 70)
Query Neighborhood Hits	170	Target Neighborhood Hits	206	Shared Neighborhood Hits	88
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

CIR_MOUSE
θ value	0.0113563 (rank : 78)	NC score	0.041084 (rank : 99)
Query Neighborhood Hits	170	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

SK2L2_HUMAN
θ value	0.0113563 (rank : 79)	NC score	0.066263 (rank : 94)
Query Neighborhood Hits	170	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	0.0113563 (rank : 80)	NC score	0.066072 (rank : 95)
Query Neighborhood Hits	170	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SKIV2_HUMAN
θ value	0.0113563 (rank : 81)	NC score	0.087577 (rank : 92)
Query Neighborhood Hits	170	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

PRP16_HUMAN
θ value	0.0148317 (rank : 82)	NC score	0.027397 (rank : 110)
Query Neighborhood Hits	170	Target Neighborhood Hits	135	Shared Neighborhood Hits	19
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

RECQ4_HUMAN
θ value	0.0148317 (rank : 83)	NC score	0.530729 (rank : 69)
Query Neighborhood Hits	170	Target Neighborhood Hits	177	Shared Neighborhood Hits	89
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

CIR_HUMAN
θ value	0.0193708 (rank : 84)	NC score	0.040566 (rank : 101)
Query Neighborhood Hits	170	Target Neighborhood Hits	249	Shared Neighborhood Hits	9
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

SFR12_MOUSE
θ value	0.0193708 (rank : 85)	NC score	0.025434 (rank : 112)
Query Neighborhood Hits	170	Target Neighborhood Hits	486	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

RECQ1_HUMAN
θ value	0.0563607 (rank : 86)	NC score	0.423293 (rank : 76)
Query Neighborhood Hits	170	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

SFR12_HUMAN
θ value	0.0563607 (rank : 87)	NC score	0.024623 (rank : 115)
Query Neighborhood Hits	170	Target Neighborhood Hits	553	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

RECQ5_HUMAN
θ value	0.0736092 (rank : 88)	NC score	0.450674 (rank : 74)
Query Neighborhood Hits	170	Target Neighborhood Hits	390	Shared Neighborhood Hits	80
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

INCE_HUMAN
θ value	0.0961366 (rank : 89)	NC score	0.008518 (rank : 135)
Query Neighborhood Hits	170	Target Neighborhood Hits	978	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

IFIH1_HUMAN
θ value	0.163984 (rank : 90)	NC score	0.313198 (rank : 82)
Query Neighborhood Hits	170	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

T2_MOUSE
θ value	0.163984 (rank : 91)	NC score	0.040298 (rank : 102)
Query Neighborhood Hits	170	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

HAP1_MOUSE
θ value	0.21417 (rank : 92)	NC score	0.013412 (rank : 129)
Query Neighborhood Hits	170	Target Neighborhood Hits	388	Shared Neighborhood Hits	10
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

RECQ1_MOUSE
θ value	0.279714 (rank : 93)	NC score	0.420316 (rank : 77)
Query Neighborhood Hits	170	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

YLPM1_HUMAN
θ value	0.365318 (rank : 94)	NC score	0.025303 (rank : 113)
Query Neighborhood Hits	170	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

IFIH1_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.297822 (rank : 85)
Query Neighborhood Hits	170	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

CT004_MOUSE
θ value	0.62314 (rank : 96)	NC score	0.017290 (rank : 121)
Query Neighborhood Hits	170	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2V5, Q3TM16, Q8VBU9	Gene names
Domain Architecture
Description	Protein C20orf4 homolog.

EI2BD_MOUSE
θ value	0.62314 (rank : 97)	NC score	0.014826 (rank : 126)
Query Neighborhood Hits	170	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q61749, Q61748, Q8VC35	Gene names	Eif2b4, Eif2b, Eif2bd, Jgr1a
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

RBM25_HUMAN
θ value	0.62314 (rank : 98)	NC score	0.006707 (rank : 144)
Query Neighborhood Hits	170	Target Neighborhood Hits	682	Shared Neighborhood Hits	19
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RU17_HUMAN
θ value	0.62314 (rank : 99)	NC score	0.017443 (rank : 120)
Query Neighborhood Hits	170	Target Neighborhood Hits	280	Shared Neighborhood Hits	14
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

TRHY_HUMAN
θ value	0.62314 (rank : 100)	NC score	0.004275 (rank : 160)
Query Neighborhood Hits	170	Target Neighborhood Hits	1385	Shared Neighborhood Hits	25
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CCHCR_HUMAN
θ value	0.813845 (rank : 101)	NC score	0.003729 (rank : 166)
Query Neighborhood Hits	170	Target Neighborhood Hits	717	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

INCE_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.008504 (rank : 136)
Query Neighborhood Hits	170	Target Neighborhood Hits	903	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

DDX58_MOUSE
θ value	1.06291 (rank : 103)	NC score	0.191322 (rank : 86)
Query Neighborhood Hits	170	Target Neighborhood Hits	99	Shared Neighborhood Hits	58
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_MOUSE
θ value	1.38821 (rank : 104)	NC score	0.133451 (rank : 90)
Query Neighborhood Hits	170	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

CYLC2_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.014470 (rank : 127)
Query Neighborhood Hits	170	Target Neighborhood Hits	223	Shared Neighborhood Hits	14
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

H2BWT_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.006283 (rank : 150)
Query Neighborhood Hits	170	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2G1	Gene names	H2BFWT
Domain Architecture	No domain graphic available
Description	Histone H2B type W-T (H2B histone family member W testis-specific).

WDR60_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.012718 (rank : 130)
Query Neighborhood Hits	170	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

DDX58_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.159343 (rank : 88)
Query Neighborhood Hits	170	Target Neighborhood Hits	105	Shared Neighborhood Hits	55
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DICER_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.373506 (rank : 80)
Query Neighborhood Hits	170	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

PRP4B_HUMAN
θ value	1.81305 (rank : 110)	NC score	-0.004901 (rank : 175)
Query Neighborhood Hits	170	Target Neighborhood Hits	1030	Shared Neighborhood Hits	12
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RN169_HUMAN
θ value	1.81305 (rank : 111)	NC score	0.013523 (rank : 128)
Query Neighborhood Hits	170	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

SNW1_HUMAN
θ value	1.81305 (rank : 112)	NC score	0.032214 (rank : 106)
Query Neighborhood Hits	170	Target Neighborhood Hits	124	Shared Neighborhood Hits	18
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

SNW1_MOUSE
θ value	1.81305 (rank : 113)	NC score	0.032284 (rank : 105)
Query Neighborhood Hits	170	Target Neighborhood Hits	125	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

U520_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.143968 (rank : 89)
Query Neighborhood Hits	170	Target Neighborhood Hits	88	Shared Neighborhood Hits	46
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

DICER_MOUSE
θ value	2.36792 (rank : 115)	NC score	0.372853 (rank : 81)
Query Neighborhood Hits	170	Target Neighborhood Hits	140	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

LC7L2_HUMAN
θ value	2.36792 (rank : 116)	NC score	0.008962 (rank : 133)
Query Neighborhood Hits	170	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

RENT2_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.007696 (rank : 140)
Query Neighborhood Hits	170	Target Neighborhood Hits	618	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RING1_MOUSE
θ value	2.36792 (rank : 118)	NC score	0.004053 (rank : 162)
Query Neighborhood Hits	170	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RU17_MOUSE
θ value	2.36792 (rank : 119)	NC score	0.015965 (rank : 123)
Query Neighborhood Hits	170	Target Neighborhood Hits	278	Shared Neighborhood Hits	16
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

SAPS2_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.006147 (rank : 151)
Query Neighborhood Hits	170	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

TR150_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.030237 (rank : 107)
Query Neighborhood Hits	170	Target Neighborhood Hits	313	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

BAT2_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.002911 (rank : 168)
Query Neighborhood Hits	170	Target Neighborhood Hits	931	Shared Neighborhood Hits	14
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FIP1_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.018454 (rank : 119)
Query Neighborhood Hits	170	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

LC7L2_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.008915 (rank : 134)
Query Neighborhood Hits	170	Target Neighborhood Hits	244	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

LGP2_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.299118 (rank : 84)
Query Neighborhood Hits	170	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

MAP9_MOUSE
θ value	3.0926 (rank : 126)	NC score	0.005774 (rank : 153)
Query Neighborhood Hits	170	Target Neighborhood Hits	529	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PCLO_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.001749 (rank : 170)
Query Neighborhood Hits	170	Target Neighborhood Hits	2046	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRP4B_MOUSE
θ value	3.0926 (rank : 128)	NC score	-0.004109 (rank : 174)
Query Neighborhood Hits	170	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

RHG06_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.003165 (rank : 167)
Query Neighborhood Hits	170	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

U2AFM_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.003796 (rank : 165)
Query Neighborhood Hits	170	Target Neighborhood Hits	577	Shared Neighborhood Hits	17
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

2A5D_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.004030 (rank : 163)
Query Neighborhood Hits	170	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

AN30A_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.000723 (rank : 171)
Query Neighborhood Hits	170	Target Neighborhood Hits	1119	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

COX10_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.008499 (rank : 137)
Query Neighborhood Hits	170	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

CYLC1_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.011509 (rank : 131)
Query Neighborhood Hits	170	Target Neighborhood Hits	408	Shared Neighborhood Hits	18
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

GA2L1_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.005310 (rank : 156)
Query Neighborhood Hits	170	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

JIP3_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.004077 (rank : 161)
Query Neighborhood Hits	170	Target Neighborhood Hits	1039	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

JIP3_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.005942 (rank : 152)
Query Neighborhood Hits	170	Target Neighborhood Hits	759	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

LGP2_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.312208 (rank : 83)
Query Neighborhood Hits	170	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

NTHL1_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.009399 (rank : 132)
Query Neighborhood Hits	170	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

PPIG_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.027078 (rank : 111)
Query Neighborhood Hits	170	Target Neighborhood Hits	670	Shared Neighborhood Hits	50
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TCAL6_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.016340 (rank : 122)
Query Neighborhood Hits	170	Target Neighborhood Hits	122	Shared Neighborhood Hits	10
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

ZC313_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.027420 (rank : 109)
Query Neighborhood Hits	170	Target Neighborhood Hits	772	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CAF1A_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.005624 (rank : 154)
Query Neighborhood Hits	170	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCD55_MOUSE
θ value	5.27518 (rank : 144)	NC score	0.037689 (rank : 103)
Query Neighborhood Hits	170	Target Neighborhood Hits	519	Shared Neighborhood Hits	47
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCHCR_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.006877 (rank : 143)
Query Neighborhood Hits	170	Target Neighborhood Hits	932	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

LBR_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.005104 (rank : 157)
Query Neighborhood Hits	170	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U9G9, Q3TSW2, Q811V8, Q811V9, Q8BST3, Q8K2Y8, Q8VDM0, Q91YS5, Q91Z27	Gene names	Lbr
Domain Architecture	No domain graphic available
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein).

NIBA_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.007522 (rank : 141)
Query Neighborhood Hits	170	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

PDCD7_MOUSE
θ value	5.27518 (rank : 148)	NC score	0.005488 (rank : 155)
Query Neighborhood Hits	170	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

ASPX_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.004847 (rank : 159)
Query Neighborhood Hits	170	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

CAF1A_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.006308 (rank : 149)
Query Neighborhood Hits	170	Target Neighborhood Hits	736	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

NSBP1_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.006704 (rank : 146)
Query Neighborhood Hits	170	Target Neighborhood Hits	251	Shared Neighborhood Hits	13
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PRKDC_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.005050 (rank : 158)
Query Neighborhood Hits	170	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

RPA1_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.003989 (rank : 164)
Query Neighborhood Hits	170	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

SNUT1_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.006363 (rank : 148)
Query Neighborhood Hits	170	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	O43290, Q53GB5	Gene names	SART1
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (Squamous cell carcinoma antigen recognized by T cells 1) (SART-1) (hSART-1) (hSnu66).

SSF1_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.006467 (rank : 147)
Query Neighborhood Hits	170	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ55, Q9BW97, Q9H170	Gene names	PPAN, SSF1
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

TCAL3_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.019205 (rank : 117)
Query Neighborhood Hits	170	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

TCAL5_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.028663 (rank : 108)
Query Neighborhood Hits	170	Target Neighborhood Hits	806	Shared Neighborhood Hits	48
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TOPRS_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.006706 (rank : 145)
Query Neighborhood Hits	170	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

DHX30_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.007497 (rank : 142)
Query Neighborhood Hits	170	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

FIP1_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.014828 (rank : 125)
Query Neighborhood Hits	170	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

MACF1_HUMAN
θ value	8.99809 (rank : 161)	NC score	-0.002808 (rank : 173)
Query Neighborhood Hits	170	Target Neighborhood Hits	1341	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	8.99809 (rank : 162)	NC score	-0.002296 (rank : 172)
Query Neighborhood Hits	170	Target Neighborhood Hits	1321	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MAP9_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.007911 (rank : 139)
Query Neighborhood Hits	170	Target Neighborhood Hits	518	Shared Neighborhood Hits	19
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

RUNX3_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.002192 (rank : 169)
Query Neighborhood Hits	170	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SFR11_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.018849 (rank : 118)
Query Neighborhood Hits	170	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFRIP_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.057072 (rank : 96)
Query Neighborhood Hits	170	Target Neighborhood Hits	530	Shared Neighborhood Hits	48
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SRRM2_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.015380 (rank : 124)
Query Neighborhood Hits	170	Target Neighborhood Hits	1470	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TR150_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.033272 (rank : 104)
Query Neighborhood Hits	170	Target Neighborhood Hits	468	Shared Neighborhood Hits	43
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

XPC_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.008420 (rank : 138)
Query Neighborhood Hits	170	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

ZN687_MOUSE
θ value	8.99809 (rank : 170)	NC score	-0.006762 (rank : 176)
Query Neighborhood Hits	170	Target Neighborhood Hits	913	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CC026_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.161348 (rank : 87)
Query Neighborhood Hits	170	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CCD55_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.053786 (rank : 97)
Query Neighborhood Hits	170	Target Neighborhood Hits	513	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

FANCM_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.386257 (rank : 78)
Query Neighborhood Hits	170	Target Neighborhood Hits	210	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.382449 (rank : 79)
Query Neighborhood Hits	170	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

HELC1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.106758 (rank : 91)
Query Neighborhood Hits	170	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.071203 (rank : 93)
Query Neighborhood Hits	170	Target Neighborhood Hits	174	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

Hits sorted by NC score

DDX54_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	170	Target Neighborhood Hits	170	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX54_MOUSE
NC score	0.995115 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	170	Target Neighborhood Hits	124	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX47_MOUSE
NC score	0.967656 (rank : 3)	θ value	4.85792e-54 (rank : 10)
Query Neighborhood Hits	170	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
NC score	0.967349 (rank : 4)	θ value	1.45929e-58 (rank : 3)
Query Neighborhood Hits	170	Target Neighborhood Hits	119	Shared Neighborhood Hits	86
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX47_HUMAN
NC score	0.967147 (rank : 5)	θ value	4.85792e-54 (rank : 9)
Query Neighborhood Hits	170	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
NC score	0.964015 (rank : 6)	θ value	2.10721e-57 (rank : 4)
Query Neighborhood Hits	170	Target Neighborhood Hits	223	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX27_MOUSE
NC score	0.961595 (rank : 7)	θ value	5.19021e-56 (rank : 7)
Query Neighborhood Hits	170	Target Neighborhood Hits	174	Shared Neighborhood Hits	87
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX6_HUMAN
NC score	0.961150 (rank : 8)	θ value	4.70527e-49 (rank : 15)
Query Neighborhood Hits	170	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.960976 (rank : 9)	θ value	4.70527e-49 (rank : 16)
Query Neighborhood Hits	170	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX27_HUMAN
NC score	0.960058 (rank : 10)	θ value	4.39379e-55 (rank : 8)
Query Neighborhood Hits	170	Target Neighborhood Hits	197	Shared Neighborhood Hits	89
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX41_HUMAN
NC score	0.956946 (rank : 11)	θ value	3.15612e-45 (rank : 29)
Query Neighborhood Hits	170	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX43_HUMAN
NC score	0.956833 (rank : 12)	θ value	1.28137e-46 (rank : 25)
Query Neighborhood Hits	170	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX41_MOUSE
NC score	0.956460 (rank : 13)	θ value	3.15612e-45 (rank : 30)
Query Neighborhood Hits	170	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX4_MOUSE
NC score	0.954895 (rank : 14)	θ value	1.51363e-47 (rank : 18)
Query Neighborhood Hits	170	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX52_MOUSE
NC score	0.954827 (rank : 15)	θ value	6.81017e-40 (rank : 41)
Query Neighborhood Hits	170	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_HUMAN
NC score	0.954803 (rank : 16)	θ value	5.21438e-40 (rank : 39)
Query Neighborhood Hits	170	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX53_HUMAN
NC score	0.954551 (rank : 17)	θ value	5.55816e-50 (rank : 12)
Query Neighborhood Hits	170	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX4_HUMAN
NC score	0.954027 (rank : 18)	θ value	1.788e-48 (rank : 17)
Query Neighborhood Hits	170	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX18_MOUSE
NC score	0.953513 (rank : 19)	θ value	2.04573e-44 (rank : 33)
Query Neighborhood Hits	170	Target Neighborhood Hits	115	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX48_HUMAN
NC score	0.953320 (rank : 20)	θ value	1.61718e-49 (rank : 13)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.953153 (rank : 21)	θ value	2.1121e-49 (rank : 14)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX17_MOUSE
NC score	0.952870 (rank : 22)	θ value	8.30557e-46 (rank : 28)
Query Neighborhood Hits	170	Target Neighborhood Hits	105	Shared Neighborhood Hits	85
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.952735 (rank : 23)	θ value	8.30557e-46 (rank : 27)
Query Neighborhood Hits	170	Target Neighborhood Hits	104	Shared Neighborhood Hits	85
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX18_HUMAN
NC score	0.952174 (rank : 24)	θ value	1.12253e-42 (rank : 38)
Query Neighborhood Hits	170	Target Neighborhood Hits	124	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX55_MOUSE
NC score	0.952011 (rank : 25)	θ value	5.76516e-39 (rank : 42)
Query Neighborhood Hits	170	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.951200 (rank : 26)	θ value	7.52953e-39 (rank : 45)
Query Neighborhood Hits	170	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX28_MOUSE
NC score	0.951166 (rank : 27)	θ value	3.86705e-35 (rank : 52)
Query Neighborhood Hits	170	Target Neighborhood Hits	112	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX5_MOUSE
NC score	0.949923 (rank : 28)	θ value	6.35935e-46 (rank : 26)
Query Neighborhood Hits	170	Target Neighborhood Hits	101	Shared Neighborhood Hits	85
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.949885 (rank : 29)	θ value	3.15612e-45 (rank : 31)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

IF4A1_HUMAN
NC score	0.949672 (rank : 30)	θ value	4.55743e-44 (rank : 34)
Query Neighborhood Hits	170	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.949672 (rank : 31)	θ value	4.55743e-44 (rank : 35)
Query Neighborhood Hits	170	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX56_HUMAN
NC score	0.949258 (rank : 32)	θ value	1.6247e-33 (rank : 54)
Query Neighborhood Hits	170	Target Neighborhood Hits	77	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

IF4A2_HUMAN
NC score	0.949125 (rank : 33)	θ value	2.26182e-43 (rank : 36)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.949125 (rank : 34)	θ value	2.26182e-43 (rank : 37)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX56_MOUSE
NC score	0.949011 (rank : 35)	θ value	2.50655e-34 (rank : 53)
Query Neighborhood Hits	170	Target Neighborhood Hits	87	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX31_HUMAN
NC score	0.948321 (rank : 36)	θ value	6.81017e-40 (rank : 40)
Query Neighborhood Hits	170	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX39_HUMAN
NC score	0.947506 (rank : 37)	θ value	1.85459e-37 (rank : 47)
Query Neighborhood Hits	170	Target Neighborhood Hits	94	Shared Neighborhood Hits	85
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX10_HUMAN
NC score	0.947405 (rank : 38)	θ value	1.97686e-47 (rank : 19)
Query Neighborhood Hits	170	Target Neighborhood Hits	210	Shared Neighborhood Hits	86
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX39_MOUSE
NC score	0.947348 (rank : 39)	θ value	3.73686e-38 (rank : 46)
Query Neighborhood Hits	170	Target Neighborhood Hits	97	Shared Neighborhood Hits	84
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX10_MOUSE
NC score	0.947342 (rank : 40)	θ value	2.58187e-47 (rank : 20)
Query Neighborhood Hits	170	Target Neighborhood Hits	233	Shared Neighborhood Hits	91
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

UAP56_HUMAN
NC score	0.947082 (rank : 41)	θ value	5.76516e-39 (rank : 43)
Query Neighborhood Hits	170	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

DDX28_HUMAN
NC score	0.947031 (rank : 42)	θ value	1.4233e-29 (rank : 65)
Query Neighborhood Hits	170	Target Neighborhood Hits	103	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

UAP56_MOUSE
NC score	0.947002 (rank : 43)	θ value	5.76516e-39 (rank : 44)
Query Neighborhood Hits	170	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX3Y_MOUSE
NC score	0.945112 (rank : 44)	θ value	1.28137e-46 (rank : 24)
Query Neighborhood Hits	170	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

PL10_MOUSE
NC score	0.944925 (rank : 45)	θ value	7.51208e-47 (rank : 23)
Query Neighborhood Hits	170	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
NC score	0.944661 (rank : 46)	θ value	2.58187e-47 (rank : 21)
Query Neighborhood Hits	170	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
NC score	0.944322 (rank : 47)	θ value	4.40402e-47 (rank : 22)
Query Neighborhood Hits	170	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
NC score	0.942816 (rank : 48)	θ value	4.122e-45 (rank : 32)
Query Neighborhood Hits	170	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX46_HUMAN
NC score	0.942543 (rank : 49)	θ value	2.32979e-56 (rank : 5)
Query Neighborhood Hits	170	Target Neighborhood Hits	357	Shared Neighborhood Hits	102
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
NC score	0.940439 (rank : 50)	θ value	2.32979e-56 (rank : 6)
Query Neighborhood Hits	170	Target Neighborhood Hits	358	Shared Neighborhood Hits	102
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX50_MOUSE
NC score	0.938612 (rank : 51)	θ value	7.04741e-37 (rank : 49)
Query Neighborhood Hits	170	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
NC score	0.938514 (rank : 52)	θ value	1.57e-36 (rank : 50)
Query Neighborhood Hits	170	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX20_HUMAN
NC score	0.935633 (rank : 53)	θ value	1.79631e-32 (rank : 56)
Query Neighborhood Hits	170	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX23_HUMAN
NC score	0.932224 (rank : 54)	θ value	7.01481e-53 (rank : 11)
Query Neighborhood Hits	170	Target Neighborhood Hits	486	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX20_MOUSE
NC score	0.932194 (rank : 55)	θ value	2.34606e-32 (rank : 57)
Query Neighborhood Hits	170	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX24_MOUSE
NC score	0.930346 (rank : 56)	θ value	3.74554e-30 (rank : 62)
Query Neighborhood Hits	170	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX51_MOUSE
NC score	0.928695 (rank : 57)	θ value	1.08979e-29 (rank : 64)
Query Neighborhood Hits	170	Target Neighborhood Hits	130	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX25_HUMAN
NC score	0.928588 (rank : 58)	θ value	4.72714e-33 (rank : 55)
Query Neighborhood Hits	170	Target Neighborhood Hits	93	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX24_HUMAN
NC score	0.927540 (rank : 59)	θ value	8.3442e-30 (rank : 63)
Query Neighborhood Hits	170	Target Neighborhood Hits	190	Shared Neighborhood Hits	84
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX25_MOUSE
NC score	0.927428 (rank : 60)	θ value	3.06405e-32 (rank : 58)
Query Neighborhood Hits	170	Target Neighborhood Hits	98	Shared Neighborhood Hits	80
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX21_HUMAN
NC score	0.926269 (rank : 61)	θ value	7.04741e-37 (rank : 48)
Query Neighborhood Hits	170	Target Neighborhood Hits	308	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DD19A_HUMAN
NC score	0.926148 (rank : 62)	θ value	8.91499e-32 (rank : 59)
Query Neighborhood Hits	170	Target Neighborhood Hits	107	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
NC score	0.925540 (rank : 63)	θ value	1.16434e-31 (rank : 60)
Query Neighborhood Hits	170	Target Neighborhood Hits	105	Shared Neighborhood Hits	81
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
NC score	0.925442 (rank : 64)	θ value	1.16434e-31 (rank : 61)
Query Neighborhood Hits	170	Target Neighborhood Hits	109	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX21_MOUSE
NC score	0.918506 (rank : 65)	θ value	1.01765e-35 (rank : 51)
Query Neighborhood Hits	170	Target Neighborhood Hits	350	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX51_HUMAN
NC score	0.911196 (rank : 66)	θ value	3.28125e-26 (rank : 66)
Query Neighborhood Hits	170	Target Neighborhood Hits	332	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX1_MOUSE
NC score	0.884089 (rank : 67)	θ value	3.17815e-21 (rank : 67)
Query Neighborhood Hits	170	Target Neighborhood Hits	112	Shared Neighborhood Hits	82
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.882427 (rank : 68)	θ value	7.0802e-21 (rank : 68)
Query Neighborhood Hits	170	Target Neighborhood Hits	110	Shared Neighborhood Hits	82
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.530729 (rank : 69)	θ value	0.0148317 (rank : 83)
Query Neighborhood Hits	170	Target Neighborhood Hits	177	Shared Neighborhood Hits	89
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.517358 (rank : 70)	θ value	0.00869519 (rank : 77)
Query Neighborhood Hits	170	Target Neighborhood Hits	206	Shared Neighborhood Hits	88
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.492944 (rank : 71)	θ value	9.29e-05 (rank : 70)
Query Neighborhood Hits	170	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.479116 (rank : 72)	θ value	0.000461057 (rank : 72)
Query Neighborhood Hits	170	Target Neighborhood Hits	148	Shared Neighborhood Hits	75
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_HUMAN
NC score	0.470921 (rank : 73)	θ value	6.43352e-06 (rank : 69)
Query Neighborhood Hits	170	Target Neighborhood Hits	132	Shared Neighborhood Hits	82
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ5_HUMAN
NC score	0.450674 (rank : 74)	θ value	0.0736092 (rank : 88)
Query Neighborhood Hits	170	Target Neighborhood Hits	390	Shared Neighborhood Hits	80
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_MOUSE
NC score	0.435904 (rank : 75)	θ value	0.000602161 (rank : 73)
Query Neighborhood Hits	170	Target Neighborhood Hits	295	Shared Neighborhood Hits	82
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_HUMAN
NC score	0.423293 (rank : 76)	θ value	0.0563607 (rank : 86)
Query Neighborhood Hits	170	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.420316 (rank : 77)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	170	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

FANCM_HUMAN
NC score	0.386257 (rank : 78)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	170	Target Neighborhood Hits	210	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.382449 (rank : 79)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	170	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_HUMAN
NC score	0.373506 (rank : 80)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	170	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.372853 (rank : 81)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	170	Target Neighborhood Hits	140	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

IFIH1_HUMAN
NC score	0.313198 (rank : 82)	θ value	0.163984 (rank : 90)
Query Neighborhood Hits	170	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_MOUSE
NC score	0.312208 (rank : 83)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	170	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

LGP2_HUMAN
NC score	0.299118 (rank : 84)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	170	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_MOUSE
NC score	0.297822 (rank : 85)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	170	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX58_MOUSE
NC score	0.191322 (rank : 86)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	170	Target Neighborhood Hits	99	Shared Neighborhood Hits	58
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_HUMAN
NC score	0.161348 (rank : 87)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	170	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX58_HUMAN
NC score	0.159343 (rank : 88)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	170	Target Neighborhood Hits	105	Shared Neighborhood Hits	55
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

U520_HUMAN
NC score	0.143968 (rank : 89)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	170	Target Neighborhood Hits	88	Shared Neighborhood Hits	46
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CC026_MOUSE
NC score	0.133451 (rank : 90)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	170	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

HELC1_HUMAN
NC score	0.106758 (rank : 91)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	170	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SKIV2_HUMAN
NC score	0.087577 (rank : 92)	θ value	0.0113563 (rank : 81)
Query Neighborhood Hits	170	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

SMAL1_HUMAN
NC score	0.071203 (rank : 93)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	170	Target Neighborhood Hits	174	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SK2L2_HUMAN
NC score	0.066263 (rank : 94)	θ value	0.0113563 (rank : 79)
Query Neighborhood Hits	170	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
NC score	0.066072 (rank : 95)	θ value	0.0113563 (rank : 80)
Query Neighborhood Hits	170	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SFRIP_HUMAN
NC score	0.057072 (rank : 96)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	170	Target Neighborhood Hits	530	Shared Neighborhood Hits	48
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CCD55_HUMAN
NC score	0.053786 (rank : 97)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	170	Target Neighborhood Hits	513	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

TMAP1_HUMAN
NC score	0.052233 (rank : 98)	θ value	0.00390308 (rank : 76)
Query Neighborhood Hits	170	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

CIR_MOUSE
NC score	0.041084 (rank : 99)	θ value	0.0113563 (rank : 78)
Query Neighborhood Hits	170	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

RPTN_MOUSE
NC score	0.040703 (rank : 100)	θ value	0.00020696 (rank : 71)
Query Neighborhood Hits	170	Target Neighborhood Hits	650	Shared Neighborhood Hits	51
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

CIR_HUMAN
NC score	0.040566 (rank : 101)	θ value	0.0193708 (rank : 84)
Query Neighborhood Hits	170	Target Neighborhood Hits	249	Shared Neighborhood Hits	9
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

T2_MOUSE
NC score	0.040298 (rank : 102)	θ value	0.163984 (rank : 91)
Query Neighborhood Hits	170	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

CCD55_MOUSE
NC score	0.037689 (rank : 103)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	170	Target Neighborhood Hits	519	Shared Neighborhood Hits	47
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

TR150_MOUSE
NC score	0.033272 (rank : 104)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	170	Target Neighborhood Hits	468	Shared Neighborhood Hits	43
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

SNW1_MOUSE
NC score	0.032284 (rank : 105)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	170	Target Neighborhood Hits	125	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

SNW1_HUMAN
NC score	0.032214 (rank : 106)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	170	Target Neighborhood Hits	124	Shared Neighborhood Hits	18
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

TR150_HUMAN
NC score	0.030237 (rank : 107)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	170	Target Neighborhood Hits	313	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TCAL5_HUMAN
NC score	0.028663 (rank : 108)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	170	Target Neighborhood Hits	806	Shared Neighborhood Hits	48
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ZC313_HUMAN
NC score	0.027420 (rank : 109)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	170	Target Neighborhood Hits	772	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

PRP16_HUMAN
NC score	0.027397 (rank : 110)	θ value	0.0148317 (rank : 82)
Query Neighborhood Hits	170	Target Neighborhood Hits	135	Shared Neighborhood Hits	19
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

PPIG_HUMAN
NC score	0.027078 (rank : 111)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	170	Target Neighborhood Hits	670	Shared Neighborhood Hits	50
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SFR12_MOUSE
NC score	0.025434 (rank : 112)	θ value	0.0193708 (rank : 85)
Query Neighborhood Hits	170	Target Neighborhood Hits	486	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

YLPM1_HUMAN
NC score	0.025303 (rank : 113)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	170	Target Neighborhood Hits	670	Shared Neighborhood Hits	25
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

SFRS4_HUMAN
NC score	0.024765 (rank : 114)	θ value	0.00175202 (rank : 74)
Query Neighborhood Hits	170	Target Neighborhood Hits	384	Shared Neighborhood Hits	15
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SFR12_HUMAN
NC score	0.024623 (rank : 115)	θ value	0.0563607 (rank : 87)
Query Neighborhood Hits	170	Target Neighborhood Hits	553	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFRS4_MOUSE
NC score	0.024023 (rank : 116)	θ value	0.00298849 (rank : 75)
Query Neighborhood Hits	170	Target Neighborhood Hits	406	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TCAL3_HUMAN
NC score	0.019205 (rank : 117)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	170	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

SFR11_HUMAN
NC score	0.018849 (rank : 118)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	170	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

FIP1_HUMAN
NC score	0.018454 (rank : 119)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	170	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

RU17_HUMAN
NC score	0.017443 (rank : 120)	θ value	0.62314 (rank : 99)
Query Neighborhood Hits	170	Target Neighborhood Hits	280	Shared Neighborhood Hits	14
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

CT004_MOUSE
NC score	0.017290 (rank : 121)	θ value	0.62314 (rank : 96)
Query Neighborhood Hits	170	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2V5, Q3TM16, Q8VBU9	Gene names
Domain Architecture
Description	Protein C20orf4 homolog.

TCAL6_HUMAN
NC score	0.016340 (rank : 122)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	170	Target Neighborhood Hits	122	Shared Neighborhood Hits	10
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

RU17_MOUSE
NC score	0.015965 (rank : 123)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	170	Target Neighborhood Hits	278	Shared Neighborhood Hits	16
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

SRRM2_MOUSE
NC score	0.015380 (rank : 124)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	170	Target Neighborhood Hits	1470	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

FIP1_MOUSE
NC score	0.014828 (rank : 125)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	170	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

EI2BD_MOUSE
NC score	0.014826 (rank : 126)	θ value	0.62314 (rank : 97)
Query Neighborhood Hits	170	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q61749, Q61748, Q8VC35	Gene names	Eif2b4, Eif2b, Eif2bd, Jgr1a
Domain Architecture
Description	Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta).

CYLC2_HUMAN
NC score	0.014470 (rank : 127)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	170	Target Neighborhood Hits	223	Shared Neighborhood Hits	14
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

RN169_HUMAN
NC score	0.013523 (rank : 128)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	170	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

HAP1_MOUSE
NC score	0.013412 (rank : 129)	θ value	0.21417 (rank : 92)
Query Neighborhood Hits	170	Target Neighborhood Hits	388	Shared Neighborhood Hits	10
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

WDR60_MOUSE
NC score	0.012718 (rank : 130)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	170	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

CYLC1_HUMAN
NC score	0.011509 (rank : 131)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	170	Target Neighborhood Hits	408	Shared Neighborhood Hits	18
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

NTHL1_HUMAN
NC score	0.009399 (rank : 132)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	170	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

LC7L2_HUMAN
NC score	0.008962 (rank : 133)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	170	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

LC7L2_MOUSE
NC score	0.008915 (rank : 134)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	170	Target Neighborhood Hits	244	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

INCE_HUMAN
NC score	0.008518 (rank : 135)	θ value	0.0961366 (rank : 89)
Query Neighborhood Hits	170	Target Neighborhood Hits	978	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
NC score	0.008504 (rank : 136)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	170	Target Neighborhood Hits	903	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

COX10_MOUSE
NC score	0.008499 (rank : 137)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	170	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFY5	Gene names	Cox10
Domain Architecture	No domain graphic available
Description	Protoheme IX farnesyltransferase, mitochondrial precursor (EC 2.5.1.-) (Heme O synthase).

XPC_MOUSE
NC score	0.008420 (rank : 138)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	170	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

MAP9_HUMAN
NC score	0.007911 (rank : 139)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	170	Target Neighborhood Hits	518	Shared Neighborhood Hits	19
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

RENT2_HUMAN
NC score	0.007696 (rank : 140)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	170	Target Neighborhood Hits	618	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

NIBA_HUMAN
NC score	0.007522 (rank : 141)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	170	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

DHX30_MOUSE
NC score	0.007497 (rank : 142)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	170	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

CCHCR_MOUSE
NC score	0.006877 (rank : 143)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	170	Target Neighborhood Hits	932	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

RBM25_HUMAN
NC score	0.006707 (rank : 144)	θ value	0.62314 (rank : 98)
Query Neighborhood Hits	170	Target Neighborhood Hits	682	Shared Neighborhood Hits	19
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TOPRS_HUMAN
NC score	0.006706 (rank : 145)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	170	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

NSBP1_HUMAN
NC score	0.006704 (rank : 146)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	170	Target Neighborhood Hits	251	Shared Neighborhood Hits	13
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

SSF1_HUMAN
NC score	0.006467 (rank : 147)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	170	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ55, Q9BW97, Q9H170	Gene names	PPAN, SSF1
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

SNUT1_HUMAN
NC score	0.006363 (rank : 148)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	170	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	O43290, Q53GB5	Gene names	SART1
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (Squamous cell carcinoma antigen recognized by T cells 1) (SART-1) (hSART-1) (hSnu66).

CAF1A_MOUSE
NC score	0.006308 (rank : 149)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	170	Target Neighborhood Hits	736	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

H2BWT_HUMAN
NC score	0.006283 (rank : 150)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	170	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z2G1	Gene names	H2BFWT
Domain Architecture	No domain graphic available
Description	Histone H2B type W-T (H2B histone family member W testis-specific).

SAPS2_HUMAN
NC score	0.006147 (rank : 151)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	170	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

JIP3_MOUSE
NC score	0.005942 (rank : 152)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	170	Target Neighborhood Hits	759	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MAP9_MOUSE
NC score	0.005774 (rank : 153)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	170	Target Neighborhood Hits	529	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

CAF1A_HUMAN
NC score	0.005624 (rank : 154)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	170	Target Neighborhood Hits	750	Shared Neighborhood Hits	17
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

PDCD7_MOUSE
NC score	0.005488 (rank : 155)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	170	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

GA2L1_HUMAN
NC score	0.005310 (rank : 156)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	170	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

LBR_MOUSE
NC score	0.005104 (rank : 157)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	170	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U9G9, Q3TSW2, Q811V8, Q811V9, Q8BST3, Q8K2Y8, Q8VDM0, Q91YS5, Q91Z27	Gene names	Lbr
Domain Architecture	No domain graphic available
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein).

PRKDC_HUMAN
NC score	0.005050 (rank : 158)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	170	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

ASPX_HUMAN
NC score	0.004847 (rank : 159)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	170	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

TRHY_HUMAN
NC score	0.004275 (rank : 160)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	170	Target Neighborhood Hits	1385	Shared Neighborhood Hits	25
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

JIP3_HUMAN
NC score	0.004077 (rank : 161)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	170	Target Neighborhood Hits	1039	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

RING1_MOUSE
NC score	0.004053 (rank : 162)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	170	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

2A5D_HUMAN
NC score	0.004030 (rank : 163)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	170	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

RPA1_HUMAN
NC score	0.003989 (rank : 164)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	170	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

U2AFM_HUMAN
NC score	0.003796 (rank : 165)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	170	Target Neighborhood Hits	577	Shared Neighborhood Hits	17
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

CCHCR_HUMAN
NC score	0.003729 (rank : 166)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	170	Target Neighborhood Hits	717	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

RHG06_HUMAN
NC score	0.003165 (rank : 167)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	170	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

BAT2_HUMAN
NC score	0.002911 (rank : 168)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	170	Target Neighborhood Hits	931	Shared Neighborhood Hits	14
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RUNX3_MOUSE
NC score	0.002192 (rank : 169)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	170	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

PCLO_HUMAN
NC score	0.001749 (rank : 170)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	170	Target Neighborhood Hits	2046	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

AN30A_HUMAN
NC score	0.000723 (rank : 171)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	170	Target Neighborhood Hits	1119	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

MACF4_HUMAN
NC score	-0.002296 (rank : 172)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	170	Target Neighborhood Hits	1321	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	-0.002808 (rank : 173)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	170	Target Neighborhood Hits	1341	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

PRP4B_MOUSE
NC score	-0.004109 (rank : 174)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	170	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

PRP4B_HUMAN
NC score	-0.004901 (rank : 175)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	170	Target Neighborhood Hits	1030	Shared Neighborhood Hits	12
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

ZN687_MOUSE
NC score	-0.006762 (rank : 176)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	170	Target Neighborhood Hits	913	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.