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Network neighborhood for query Sequence : IFIH1_MOUSE

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IFIH1_MOUSE
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IFIH1_HUMAN
θ value	0 (rank : 1)	NC score	0.987259 (rank : 2)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	126
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LGP2_MOUSE
θ value	1.47209e-143 (rank : 3)	NC score	0.951402 (rank : 4)
Query Neighborhood Hits	126	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

LGP2_HUMAN
θ value	1.62758e-142 (rank : 4)	NC score	0.952091 (rank : 3)
Query Neighborhood Hits	126	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

DDX58_HUMAN
θ value	5.29683e-101 (rank : 5)	NC score	0.895503 (rank : 6)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	61
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	2.30293e-96 (rank : 6)	NC score	0.901013 (rank : 5)
Query Neighborhood Hits	126	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

FANCM_MOUSE
θ value	2.35696e-16 (rank : 7)	NC score	0.556426 (rank : 9)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_MOUSE
θ value	1.52774e-15 (rank : 8)	NC score	0.573400 (rank : 7)
Query Neighborhood Hits	126	Target Neighborhood Hits	140	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
θ value	3.40345e-15 (rank : 9)	NC score	0.570915 (rank : 8)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

FANCM_HUMAN
θ value	2.43908e-13 (rank : 10)	NC score	0.546745 (rank : 10)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

DDX48_HUMAN
θ value	9.29e-05 (rank : 11)	NC score	0.357331 (rank : 16)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	9.29e-05 (rank : 12)	NC score	0.357340 (rank : 15)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX5_HUMAN
θ value	0.000121331 (rank : 13)	NC score	0.345047 (rank : 22)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	0.000121331 (rank : 14)	NC score	0.345146 (rank : 21)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	82
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

IF4A1_HUMAN
θ value	0.000121331 (rank : 15)	NC score	0.359954 (rank : 11)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	0.000121331 (rank : 16)	NC score	0.359954 (rank : 12)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	0.000158464 (rank : 17)	NC score	0.358537 (rank : 13)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	0.000158464 (rank : 18)	NC score	0.358537 (rank : 14)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX17_HUMAN
θ value	0.000602161 (rank : 19)	NC score	0.347136 (rank : 18)
Query Neighborhood Hits	126	Target Neighborhood Hits	104	Shared Neighborhood Hits	81
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	0.000602161 (rank : 20)	NC score	0.347177 (rank : 17)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	81
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX52_HUMAN
θ value	0.000602161 (rank : 21)	NC score	0.345703 (rank : 20)
Query Neighborhood Hits	126	Target Neighborhood Hits	107	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
θ value	0.000602161 (rank : 22)	NC score	0.344886 (rank : 23)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX50_HUMAN
θ value	0.000786445 (rank : 23)	NC score	0.343672 (rank : 25)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

CJ118_MOUSE
θ value	0.00134147 (rank : 24)	NC score	0.035370 (rank : 94)
Query Neighborhood Hits	126	Target Neighborhood Hits	1132	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

DDX27_HUMAN
θ value	0.00134147 (rank : 25)	NC score	0.343121 (rank : 27)
Query Neighborhood Hits	126	Target Neighborhood Hits	197	Shared Neighborhood Hits	82
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_MOUSE
θ value	0.00228821 (rank : 26)	NC score	0.337886 (rank : 33)
Query Neighborhood Hits	126	Target Neighborhood Hits	174	Shared Neighborhood Hits	81
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX25_MOUSE
θ value	0.00298849 (rank : 27)	NC score	0.337307 (rank : 35)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX46_HUMAN
θ value	0.00298849 (rank : 28)	NC score	0.345837 (rank : 19)
Query Neighborhood Hits	126	Target Neighborhood Hits	357	Shared Neighborhood Hits	91
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	0.00298849 (rank : 29)	NC score	0.344886 (rank : 24)
Query Neighborhood Hits	126	Target Neighborhood Hits	358	Shared Neighborhood Hits	91
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX1_MOUSE
θ value	0.00390308 (rank : 30)	NC score	0.310220 (rank : 58)
Query Neighborhood Hits	126	Target Neighborhood Hits	112	Shared Neighborhood Hits	78
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX3X_MOUSE
θ value	0.00390308 (rank : 31)	NC score	0.343362 (rank : 26)
Query Neighborhood Hits	126	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX43_HUMAN
θ value	0.00390308 (rank : 32)	NC score	0.337089 (rank : 36)
Query Neighborhood Hits	126	Target Neighborhood Hits	120	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX47_HUMAN
θ value	0.00390308 (rank : 33)	NC score	0.335466 (rank : 39)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	0.00390308 (rank : 34)	NC score	0.334863 (rank : 40)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
θ value	0.00390308 (rank : 35)	NC score	0.331790 (rank : 43)
Query Neighborhood Hits	126	Target Neighborhood Hits	223	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX3X_HUMAN
θ value	0.00509761 (rank : 36)	NC score	0.342858 (rank : 28)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_MOUSE
θ value	0.00509761 (rank : 37)	NC score	0.342527 (rank : 29)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX50_MOUSE
θ value	0.00665767 (rank : 38)	NC score	0.337065 (rank : 37)
Query Neighborhood Hits	126	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX25_HUMAN
θ value	0.00869519 (rank : 39)	NC score	0.332938 (rank : 42)
Query Neighborhood Hits	126	Target Neighborhood Hits	93	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

PL10_MOUSE
θ value	0.00869519 (rank : 40)	NC score	0.339336 (rank : 32)
Query Neighborhood Hits	126	Target Neighborhood Hits	120	Shared Neighborhood Hits	81
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

CENPE_HUMAN
θ value	0.0113563 (rank : 41)	NC score	0.022584 (rank : 105)
Query Neighborhood Hits	126	Target Neighborhood Hits	2060	Shared Neighborhood Hits	36
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DDX1_HUMAN
θ value	0.0113563 (rank : 42)	NC score	0.307239 (rank : 60)
Query Neighborhood Hits	126	Target Neighborhood Hits	110	Shared Neighborhood Hits	78
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX39_HUMAN
θ value	0.0113563 (rank : 43)	NC score	0.318510 (rank : 54)
Query Neighborhood Hits	126	Target Neighborhood Hits	94	Shared Neighborhood Hits	80
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
θ value	0.0113563 (rank : 44)	NC score	0.316427 (rank : 55)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX51_MOUSE
θ value	0.0113563 (rank : 45)	NC score	0.335916 (rank : 38)
Query Neighborhood Hits	126	Target Neighborhood Hits	130	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

HELC1_HUMAN
θ value	0.0113563 (rank : 46)	NC score	0.212184 (rank : 81)
Query Neighborhood Hits	126	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

UAP56_HUMAN
θ value	0.0113563 (rank : 47)	NC score	0.310702 (rank : 56)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	0.0113563 (rank : 48)	NC score	0.310664 (rank : 57)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

CYLC1_HUMAN
θ value	0.0148317 (rank : 49)	NC score	0.050120 (rank : 91)
Query Neighborhood Hits	126	Target Neighborhood Hits	408	Shared Neighborhood Hits	15
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DDX3Y_HUMAN
θ value	0.0148317 (rank : 50)	NC score	0.341026 (rank : 30)
Query Neighborhood Hits	126	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX21_HUMAN
θ value	0.0193708 (rank : 51)	NC score	0.334033 (rank : 41)
Query Neighborhood Hits	126	Target Neighborhood Hits	308	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX23_HUMAN
θ value	0.0193708 (rank : 52)	NC score	0.328848 (rank : 44)
Query Neighborhood Hits	126	Target Neighborhood Hits	486	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX49_MOUSE
θ value	0.0193708 (rank : 53)	NC score	0.325956 (rank : 49)
Query Neighborhood Hits	126	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

U520_HUMAN
θ value	0.0193708 (rank : 54)	NC score	0.183148 (rank : 82)
Query Neighborhood Hits	126	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

RBCC1_MOUSE
θ value	0.0252991 (rank : 55)	NC score	0.039910 (rank : 92)
Query Neighborhood Hits	126	Target Neighborhood Hits	1048	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

DDX4_MOUSE
θ value	0.0330416 (rank : 56)	NC score	0.339603 (rank : 31)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	83
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX55_HUMAN
θ value	0.0330416 (rank : 57)	NC score	0.309316 (rank : 59)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

FER_HUMAN
θ value	0.0330416 (rank : 58)	NC score	0.005112 (rank : 128)
Query Neighborhood Hits	126	Target Neighborhood Hits	1278	Shared Neighborhood Hits	14
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

DD19A_HUMAN
θ value	0.0431538 (rank : 59)	NC score	0.319918 (rank : 51)
Query Neighborhood Hits	126	Target Neighborhood Hits	107	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	0.0431538 (rank : 60)	NC score	0.320248 (rank : 50)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	77
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	0.0431538 (rank : 61)	NC score	0.319829 (rank : 52)
Query Neighborhood Hits	126	Target Neighborhood Hits	109	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX4_HUMAN
θ value	0.0431538 (rank : 62)	NC score	0.337885 (rank : 34)
Query Neighborhood Hits	126	Target Neighborhood Hits	123	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX21_MOUSE
θ value	0.0563607 (rank : 63)	NC score	0.328799 (rank : 45)
Query Neighborhood Hits	126	Target Neighborhood Hits	350	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX41_HUMAN
θ value	0.0736092 (rank : 64)	NC score	0.328357 (rank : 46)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	0.0736092 (rank : 65)	NC score	0.328324 (rank : 47)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	82
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

RBCC1_HUMAN
θ value	0.0961366 (rank : 66)	NC score	0.036970 (rank : 93)
Query Neighborhood Hits	126	Target Neighborhood Hits	1023	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

DDX54_MOUSE
θ value	0.125558 (rank : 67)	NC score	0.298916 (rank : 65)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

RECQ4_MOUSE
θ value	0.125558 (rank : 68)	NC score	0.243066 (rank : 80)
Query Neighborhood Hits	126	Target Neighborhood Hits	206	Shared Neighborhood Hits	79
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DDX53_HUMAN
θ value	0.163984 (rank : 69)	NC score	0.319221 (rank : 53)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

CCAR1_HUMAN
θ value	0.21417 (rank : 70)	NC score	0.029573 (rank : 95)
Query Neighborhood Hits	126	Target Neighborhood Hits	444	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CTRO_MOUSE
θ value	0.21417 (rank : 71)	NC score	0.010027 (rank : 117)
Query Neighborhood Hits	126	Target Neighborhood Hits	2344	Shared Neighborhood Hits	36
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DDX24_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.291840 (rank : 68)
Query Neighborhood Hits	126	Target Neighborhood Hits	190	Shared Neighborhood Hits	81
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

RECQ4_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.255645 (rank : 79)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	81
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

DDX55_MOUSE
θ value	0.279714 (rank : 74)	NC score	0.304694 (rank : 61)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX51_HUMAN
θ value	0.365318 (rank : 75)	NC score	0.326096 (rank : 48)
Query Neighborhood Hits	126	Target Neighborhood Hits	332	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX54_HUMAN
θ value	0.47712 (rank : 76)	NC score	0.297822 (rank : 66)
Query Neighborhood Hits	126	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

WRN_MOUSE
θ value	0.47712 (rank : 77)	NC score	0.172204 (rank : 86)
Query Neighborhood Hits	126	Target Neighborhood Hits	295	Shared Neighborhood Hits	77
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_MOUSE
θ value	0.62314 (rank : 78)	NC score	0.171867 (rank : 87)
Query Neighborhood Hits	126	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

CR034_HUMAN
θ value	0.813845 (rank : 79)	NC score	0.027767 (rank : 96)
Query Neighborhood Hits	126	Target Neighborhood Hits	538	Shared Neighborhood Hits	21
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

ROCK1_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.007951 (rank : 123)
Query Neighborhood Hits	126	Target Neighborhood Hits	2000	Shared Neighborhood Hits	32
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

PLCB1_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.025953 (rank : 97)
Query Neighborhood Hits	126	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

CTGE6_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.023772 (rank : 102)
Query Neighborhood Hits	126	Target Neighborhood Hits	650	Shared Neighborhood Hits	20
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

GSCR1_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.013626 (rank : 113)
Query Neighborhood Hits	126	Target Neighborhood Hits	674	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PLCB1_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.024442 (rank : 101)
Query Neighborhood Hits	126	Target Neighborhood Hits	531	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

RECQ1_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.172933 (rank : 84)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

STK10_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.006945 (rank : 124)
Query Neighborhood Hits	126	Target Neighborhood Hits	2132	Shared Neighborhood Hits	35
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZBTB3_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.001000 (rank : 133)
Query Neighborhood Hits	126	Target Neighborhood Hits	910	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

CTGE4_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.024961 (rank : 99)
Query Neighborhood Hits	126	Target Neighborhood Hits	393	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

DDX24_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.290584 (rank : 69)
Query Neighborhood Hits	126	Target Neighborhood Hits	147	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

EURL_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.022924 (rank : 104)
Query Neighborhood Hits	126	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7G4	Gene names	Eurl, D16Ertd472e
Domain Architecture
Description	Protein EURL homolog.

NUF2_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.024767 (rank : 100)
Query Neighborhood Hits	126	Target Neighborhood Hits	661	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

ROCK1_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.008321 (rank : 121)
Query Neighborhood Hits	126	Target Neighborhood Hits	2126	Shared Neighborhood Hits	37
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

DDX10_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.276063 (rank : 74)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	78
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_MOUSE
θ value	3.0926 (rank : 94)	NC score	0.287447 (rank : 70)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX31_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.293102 (rank : 67)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

WRN_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.172870 (rank : 85)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	78
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

ARMC6_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.017250 (rank : 109)
Query Neighborhood Hits	126	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

CYLC2_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.023454 (rank : 103)
Query Neighborhood Hits	126	Target Neighborhood Hits	223	Shared Neighborhood Hits	7
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DDX6_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.303669 (rank : 63)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.303244 (rank : 64)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	81
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

HIP1_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.014443 (rank : 112)
Query Neighborhood Hits	126	Target Neighborhood Hits	1016	Shared Neighborhood Hits	29
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

PPIP1_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.010737 (rank : 116)
Query Neighborhood Hits	126	Target Neighborhood Hits	389	Shared Neighborhood Hits	11
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

DDX20_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.285202 (rank : 72)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX28_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.304267 (rank : 62)
Query Neighborhood Hits	126	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

LAMA4_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.010836 (rank : 115)
Query Neighborhood Hits	126	Target Neighborhood Hits	584	Shared Neighborhood Hits	14
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MIPO1_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.020553 (rank : 107)
Query Neighborhood Hits	126	Target Neighborhood Hits	486	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

NUF2_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.025069 (rank : 98)
Query Neighborhood Hits	126	Target Neighborhood Hits	585	Shared Neighborhood Hits	20
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

ARI4A_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.015418 (rank : 111)
Query Neighborhood Hits	126	Target Neighborhood Hits	434	Shared Neighborhood Hits	18
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BPTF_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.009841 (rank : 118)
Query Neighborhood Hits	126	Target Neighborhood Hits	786	Shared Neighborhood Hits	18
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CE290_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.017488 (rank : 108)
Query Neighborhood Hits	126	Target Neighborhood Hits	1553	Shared Neighborhood Hits	30
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

DDX56_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.275366 (rank : 75)
Query Neighborhood Hits	126	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DHX9_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.006472 (rank : 125)
Query Neighborhood Hits	126	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

EP3B_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.016634 (rank : 110)
Query Neighborhood Hits	126	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P56851	Gene names	FAM12B, HE3BETA
Domain Architecture	No domain graphic available
Description	Epididymal secretory protein E3 beta precursor (HE3 beta).

HIF1A_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.004727 (rank : 129)
Query Neighborhood Hits	126	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

OSBL1_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.001395 (rank : 132)
Query Neighborhood Hits	126	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

SPTA2_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.008514 (rank : 120)
Query Neighborhood Hits	126	Target Neighborhood Hits	888	Shared Neighborhood Hits	21
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

DDX20_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.286827 (rank : 71)
Query Neighborhood Hits	126	Target Neighborhood Hits	121	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX56_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.274546 (rank : 76)
Query Neighborhood Hits	126	Target Neighborhood Hits	77	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

ERCC3_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.020897 (rank : 106)
Query Neighborhood Hits	126	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P49135	Gene names	Ercc3, Xpb, Xpbc
Domain Architecture
Description	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) (Basic transcription factor 2 89 kDa subunit) (BTF2-p89) (TFIIH 89 kDa subunit) (DNA-repair protein complementing XP-B cells) (Xeroderma pigmentosum group B-complementing protein) (DNA excision repair protein ERCC-3).

GCYB1_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.006142 (rank : 127)
Query Neighborhood Hits	126	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q02153, Q86WY5	Gene names	GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit) (GCS-beta-3).

GCYB1_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.006148 (rank : 126)
Query Neighborhood Hits	126	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O54865	Gene names	Gucy1b3
Domain Architecture	No domain graphic available
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit).

LAMA1_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.004585 (rank : 130)
Query Neighborhood Hits	126	Target Neighborhood Hits	838	Shared Neighborhood Hits	16
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LY75_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.003063 (rank : 131)
Query Neighborhood Hits	126	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

MYH11_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.010930 (rank : 114)
Query Neighborhood Hits	126	Target Neighborhood Hits	1777	Shared Neighborhood Hits	36
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

P66A_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.007984 (rank : 122)
Query Neighborhood Hits	126	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CHY6, Q8BTQ2, Q8VEC9	Gene names	Gatad2a
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (GATA zinc finger domain- containing protein 2A).

ZN330_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.009506 (rank : 119)
Query Neighborhood Hits	126	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

BLM_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.153707 (rank : 89)
Query Neighborhood Hits	126	Target Neighborhood Hits	148	Shared Neighborhood Hits	68
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.157751 (rank : 88)
Query Neighborhood Hits	126	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

CC026_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.054889 (rank : 90)
Query Neighborhood Hits	126	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX10_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.274276 (rank : 77)
Query Neighborhood Hits	126	Target Neighborhood Hits	233	Shared Neighborhood Hits	79
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.276707 (rank : 73)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX28_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.272101 (rank : 78)
Query Neighborhood Hits	126	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

RECQ5_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.174938 (rank : 83)
Query Neighborhood Hits	126	Target Neighborhood Hits	390	Shared Neighborhood Hits	74
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

Hits sorted by NC score

IFIH1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	126
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

IFIH1_HUMAN
NC score	0.987259 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
NC score	0.952091 (rank : 3)	θ value	1.62758e-142 (rank : 4)
Query Neighborhood Hits	126	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

LGP2_MOUSE
NC score	0.951402 (rank : 4)	θ value	1.47209e-143 (rank : 3)
Query Neighborhood Hits	126	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

DDX58_MOUSE
NC score	0.901013 (rank : 5)	θ value	2.30293e-96 (rank : 6)
Query Neighborhood Hits	126	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.895503 (rank : 6)	θ value	5.29683e-101 (rank : 5)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	61
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DICER_MOUSE
NC score	0.573400 (rank : 7)	θ value	1.52774e-15 (rank : 8)
Query Neighborhood Hits	126	Target Neighborhood Hits	140	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.570915 (rank : 8)	θ value	3.40345e-15 (rank : 9)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

FANCM_MOUSE
NC score	0.556426 (rank : 9)	θ value	2.35696e-16 (rank : 7)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

FANCM_HUMAN
NC score	0.546745 (rank : 10)	θ value	2.43908e-13 (rank : 10)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

IF4A1_HUMAN
NC score	0.359954 (rank : 11)	θ value	0.000121331 (rank : 15)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.359954 (rank : 12)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
NC score	0.358537 (rank : 13)	θ value	0.000158464 (rank : 17)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.358537 (rank : 14)	θ value	0.000158464 (rank : 18)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX48_MOUSE
NC score	0.357340 (rank : 15)	θ value	9.29e-05 (rank : 12)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX48_HUMAN
NC score	0.357331 (rank : 16)	θ value	9.29e-05 (rank : 11)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX17_MOUSE
NC score	0.347177 (rank : 17)	θ value	0.000602161 (rank : 20)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	81
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.347136 (rank : 18)	θ value	0.000602161 (rank : 19)
Query Neighborhood Hits	126	Target Neighborhood Hits	104	Shared Neighborhood Hits	81
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX46_HUMAN
NC score	0.345837 (rank : 19)	θ value	0.00298849 (rank : 28)
Query Neighborhood Hits	126	Target Neighborhood Hits	357	Shared Neighborhood Hits	91
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX52_HUMAN
NC score	0.345703 (rank : 20)	θ value	0.000602161 (rank : 21)
Query Neighborhood Hits	126	Target Neighborhood Hits	107	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX5_MOUSE
NC score	0.345146 (rank : 21)	θ value	0.000121331 (rank : 14)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	82
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.345047 (rank : 22)	θ value	0.000121331 (rank : 13)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX52_MOUSE
NC score	0.344886 (rank : 23)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	83
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX46_MOUSE
NC score	0.344886 (rank : 24)	θ value	0.00298849 (rank : 29)
Query Neighborhood Hits	126	Target Neighborhood Hits	358	Shared Neighborhood Hits	91
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX50_HUMAN
NC score	0.343672 (rank : 25)	θ value	0.000786445 (rank : 23)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX3X_MOUSE
NC score	0.343362 (rank : 26)	θ value	0.00390308 (rank : 31)
Query Neighborhood Hits	126	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX27_HUMAN
NC score	0.343121 (rank : 27)	θ value	0.00134147 (rank : 25)
Query Neighborhood Hits	126	Target Neighborhood Hits	197	Shared Neighborhood Hits	82
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX3X_HUMAN
NC score	0.342858 (rank : 28)	θ value	0.00509761 (rank : 36)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_MOUSE
NC score	0.342527 (rank : 29)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX3Y_HUMAN
NC score	0.341026 (rank : 30)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	126	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX4_MOUSE
NC score	0.339603 (rank : 31)	θ value	0.0330416 (rank : 56)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	83
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

PL10_MOUSE
NC score	0.339336 (rank : 32)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	126	Target Neighborhood Hits	120	Shared Neighborhood Hits	81
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX27_MOUSE
NC score	0.337886 (rank : 33)	θ value	0.00228821 (rank : 26)
Query Neighborhood Hits	126	Target Neighborhood Hits	174	Shared Neighborhood Hits	81
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX4_HUMAN
NC score	0.337885 (rank : 34)	θ value	0.0431538 (rank : 62)
Query Neighborhood Hits	126	Target Neighborhood Hits	123	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX25_MOUSE
NC score	0.337307 (rank : 35)	θ value	0.00298849 (rank : 27)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX43_HUMAN
NC score	0.337089 (rank : 36)	θ value	0.00390308 (rank : 32)
Query Neighborhood Hits	126	Target Neighborhood Hits	120	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX50_MOUSE
NC score	0.337065 (rank : 37)	θ value	0.00665767 (rank : 38)
Query Neighborhood Hits	126	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX51_MOUSE
NC score	0.335916 (rank : 38)	θ value	0.0113563 (rank : 45)
Query Neighborhood Hits	126	Target Neighborhood Hits	130	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX47_HUMAN
NC score	0.335466 (rank : 39)	θ value	0.00390308 (rank : 33)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
NC score	0.334863 (rank : 40)	θ value	0.00390308 (rank : 34)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX21_HUMAN
NC score	0.334033 (rank : 41)	θ value	0.0193708 (rank : 51)
Query Neighborhood Hits	126	Target Neighborhood Hits	308	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX25_HUMAN
NC score	0.332938 (rank : 42)	θ value	0.00869519 (rank : 39)
Query Neighborhood Hits	126	Target Neighborhood Hits	93	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX49_HUMAN
NC score	0.331790 (rank : 43)	θ value	0.00390308 (rank : 35)
Query Neighborhood Hits	126	Target Neighborhood Hits	223	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX23_HUMAN
NC score	0.328848 (rank : 44)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	126	Target Neighborhood Hits	486	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX21_MOUSE
NC score	0.328799 (rank : 45)	θ value	0.0563607 (rank : 63)
Query Neighborhood Hits	126	Target Neighborhood Hits	350	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX41_HUMAN
NC score	0.328357 (rank : 46)	θ value	0.0736092 (rank : 64)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.328324 (rank : 47)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	82
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX51_HUMAN
NC score	0.326096 (rank : 48)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	126	Target Neighborhood Hits	332	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX49_MOUSE
NC score	0.325956 (rank : 49)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	126	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DD19A_MOUSE
NC score	0.320248 (rank : 50)	θ value	0.0431538 (rank : 60)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	77
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19A_HUMAN
NC score	0.319918 (rank : 51)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	126	Target Neighborhood Hits	107	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.319829 (rank : 52)	θ value	0.0431538 (rank : 61)
Query Neighborhood Hits	126	Target Neighborhood Hits	109	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX53_HUMAN
NC score	0.319221 (rank : 53)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX39_HUMAN
NC score	0.318510 (rank : 54)	θ value	0.0113563 (rank : 43)
Query Neighborhood Hits	126	Target Neighborhood Hits	94	Shared Neighborhood Hits	80
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
NC score	0.316427 (rank : 55)	θ value	0.0113563 (rank : 44)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

UAP56_HUMAN
NC score	0.310702 (rank : 56)	θ value	0.0113563 (rank : 47)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.310664 (rank : 57)	θ value	0.0113563 (rank : 48)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX1_MOUSE
NC score	0.310220 (rank : 58)	θ value	0.00390308 (rank : 30)
Query Neighborhood Hits	126	Target Neighborhood Hits	112	Shared Neighborhood Hits	78
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX55_HUMAN
NC score	0.309316 (rank : 59)	θ value	0.0330416 (rank : 57)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX1_HUMAN
NC score	0.307239 (rank : 60)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	126	Target Neighborhood Hits	110	Shared Neighborhood Hits	78
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX55_MOUSE
NC score	0.304694 (rank : 61)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX28_MOUSE
NC score	0.304267 (rank : 62)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	126	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX6_HUMAN
NC score	0.303669 (rank : 63)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	81
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.303244 (rank : 64)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	81
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX54_MOUSE
NC score	0.298916 (rank : 65)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX54_HUMAN
NC score	0.297822 (rank : 66)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	126	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX31_HUMAN
NC score	0.293102 (rank : 67)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX24_HUMAN
NC score	0.291840 (rank : 68)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	126	Target Neighborhood Hits	190	Shared Neighborhood Hits	81
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_MOUSE
NC score	0.290584 (rank : 69)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	126	Target Neighborhood Hits	147	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX18_MOUSE
NC score	0.287447 (rank : 70)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX20_HUMAN
NC score	0.286827 (rank : 71)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	126	Target Neighborhood Hits	121	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
NC score	0.285202 (rank : 72)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX18_HUMAN
NC score	0.276707 (rank : 73)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX10_HUMAN
NC score	0.276063 (rank : 74)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	78
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX56_MOUSE
NC score	0.275366 (rank : 75)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	126	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
NC score	0.274546 (rank : 76)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	126	Target Neighborhood Hits	77	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX10_MOUSE
NC score	0.274276 (rank : 77)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	126	Target Neighborhood Hits	233	Shared Neighborhood Hits	79
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX28_HUMAN
NC score	0.272101 (rank : 78)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	126	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

RECQ4_HUMAN
NC score	0.255645 (rank : 79)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	81
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.243066 (rank : 80)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	126	Target Neighborhood Hits	206	Shared Neighborhood Hits	79
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

HELC1_HUMAN
NC score	0.212184 (rank : 81)	θ value	0.0113563 (rank : 46)
Query Neighborhood Hits	126	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

U520_HUMAN
NC score	0.183148 (rank : 82)	θ value	0.0193708 (rank : 54)
Query Neighborhood Hits	126	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

RECQ5_HUMAN
NC score	0.174938 (rank : 83)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	126	Target Neighborhood Hits	390	Shared Neighborhood Hits	74
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RECQ1_HUMAN
NC score	0.172933 (rank : 84)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_HUMAN
NC score	0.172870 (rank : 85)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	78
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
NC score	0.172204 (rank : 86)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	126	Target Neighborhood Hits	295	Shared Neighborhood Hits	77
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_MOUSE
NC score	0.171867 (rank : 87)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	126	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

BLM_MOUSE
NC score	0.157751 (rank : 88)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	126	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.153707 (rank : 89)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	126	Target Neighborhood Hits	148	Shared Neighborhood Hits	68
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

CC026_HUMAN
NC score	0.054889 (rank : 90)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	126	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CYLC1_HUMAN
NC score	0.050120 (rank : 91)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	126	Target Neighborhood Hits	408	Shared Neighborhood Hits	15
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

RBCC1_MOUSE
NC score	0.039910 (rank : 92)	θ value	0.0252991 (rank : 55)
Query Neighborhood Hits	126	Target Neighborhood Hits	1048	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBCC1_HUMAN
NC score	0.036970 (rank : 93)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	126	Target Neighborhood Hits	1023	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CJ118_MOUSE
NC score	0.035370 (rank : 94)	θ value	0.00134147 (rank : 24)
Query Neighborhood Hits	126	Target Neighborhood Hits	1132	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CCAR1_HUMAN
NC score	0.029573 (rank : 95)	θ value	0.21417 (rank : 70)
Query Neighborhood Hits	126	Target Neighborhood Hits	444	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CR034_HUMAN
NC score	0.027767 (rank : 96)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	126	Target Neighborhood Hits	538	Shared Neighborhood Hits	21
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

PLCB1_HUMAN
NC score	0.025953 (rank : 97)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	126	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

NUF2_MOUSE
NC score	0.025069 (rank : 98)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	126	Target Neighborhood Hits	585	Shared Neighborhood Hits	20
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

CTGE4_HUMAN
NC score	0.024961 (rank : 99)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	126	Target Neighborhood Hits	393	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

NUF2_HUMAN
NC score	0.024767 (rank : 100)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	126	Target Neighborhood Hits	661	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

PLCB1_MOUSE
NC score	0.024442 (rank : 101)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	126	Target Neighborhood Hits	531	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

CTGE6_HUMAN
NC score	0.023772 (rank : 102)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	126	Target Neighborhood Hits	650	Shared Neighborhood Hits	20
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

CYLC2_HUMAN
NC score	0.023454 (rank : 103)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	126	Target Neighborhood Hits	223	Shared Neighborhood Hits	7
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

EURL_MOUSE
NC score	0.022924 (rank : 104)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	126	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7G4	Gene names	Eurl, D16Ertd472e
Domain Architecture
Description	Protein EURL homolog.

CENPE_HUMAN
NC score	0.022584 (rank : 105)	θ value	0.0113563 (rank : 41)
Query Neighborhood Hits	126	Target Neighborhood Hits	2060	Shared Neighborhood Hits	36
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ERCC3_MOUSE
NC score	0.020897 (rank : 106)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	126	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P49135	Gene names	Ercc3, Xpb, Xpbc
Domain Architecture
Description	TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) (Basic transcription factor 2 89 kDa subunit) (BTF2-p89) (TFIIH 89 kDa subunit) (DNA-repair protein complementing XP-B cells) (Xeroderma pigmentosum group B-complementing protein) (DNA excision repair protein ERCC-3).

MIPO1_HUMAN
NC score	0.020553 (rank : 107)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	126	Target Neighborhood Hits	486	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

CE290_HUMAN
NC score	0.017488 (rank : 108)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	126	Target Neighborhood Hits	1553	Shared Neighborhood Hits	30
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

ARMC6_MOUSE
NC score	0.017250 (rank : 109)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	126	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

EP3B_HUMAN
NC score	0.016634 (rank : 110)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	126	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	P56851	Gene names	FAM12B, HE3BETA
Domain Architecture	No domain graphic available
Description	Epididymal secretory protein E3 beta precursor (HE3 beta).

ARI4A_HUMAN
NC score	0.015418 (rank : 111)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	126	Target Neighborhood Hits	434	Shared Neighborhood Hits	18
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

HIP1_HUMAN
NC score	0.014443 (rank : 112)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	126	Target Neighborhood Hits	1016	Shared Neighborhood Hits	29
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

GSCR1_HUMAN
NC score	0.013626 (rank : 113)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	126	Target Neighborhood Hits	674	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MYH11_MOUSE
NC score	0.010930 (rank : 114)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	126	Target Neighborhood Hits	1777	Shared Neighborhood Hits	36
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

LAMA4_MOUSE
NC score	0.010836 (rank : 115)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	126	Target Neighborhood Hits	584	Shared Neighborhood Hits	14
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

PPIP1_HUMAN
NC score	0.010737 (rank : 116)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	126	Target Neighborhood Hits	389	Shared Neighborhood Hits	11
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

CTRO_MOUSE
NC score	0.010027 (rank : 117)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	126	Target Neighborhood Hits	2344	Shared Neighborhood Hits	36
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

BPTF_HUMAN
NC score	0.009841 (rank : 118)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	126	Target Neighborhood Hits	786	Shared Neighborhood Hits	18
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

ZN330_HUMAN
NC score	0.009506 (rank : 119)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	126	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

SPTA2_HUMAN
NC score	0.008514 (rank : 120)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	126	Target Neighborhood Hits	888	Shared Neighborhood Hits	21
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ROCK1_MOUSE
NC score	0.008321 (rank : 121)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	126	Target Neighborhood Hits	2126	Shared Neighborhood Hits	37
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

P66A_MOUSE
NC score	0.007984 (rank : 122)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	126	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CHY6, Q8BTQ2, Q8VEC9	Gene names	Gatad2a
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (GATA zinc finger domain- containing protein 2A).

ROCK1_HUMAN
NC score	0.007951 (rank : 123)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	126	Target Neighborhood Hits	2000	Shared Neighborhood Hits	32
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

STK10_MOUSE
NC score	0.006945 (rank : 124)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	126	Target Neighborhood Hits	2132	Shared Neighborhood Hits	35
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

DHX9_MOUSE
NC score	0.006472 (rank : 125)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	126	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

GCYB1_MOUSE
NC score	0.006148 (rank : 126)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	126	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O54865	Gene names	Gucy1b3
Domain Architecture	No domain graphic available
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit).

GCYB1_HUMAN
NC score	0.006142 (rank : 127)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	126	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q02153, Q86WY5	Gene names	GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit) (GCS-beta-3).

FER_HUMAN
NC score	0.005112 (rank : 128)	θ value	0.0330416 (rank : 58)
Query Neighborhood Hits	126	Target Neighborhood Hits	1278	Shared Neighborhood Hits	14
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

HIF1A_HUMAN
NC score	0.004727 (rank : 129)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	126	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

LAMA1_MOUSE
NC score	0.004585 (rank : 130)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	126	Target Neighborhood Hits	838	Shared Neighborhood Hits	16
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LY75_HUMAN
NC score	0.003063 (rank : 131)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	126	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

OSBL1_HUMAN
NC score	0.001395 (rank : 132)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	126	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ZBTB3_HUMAN
NC score	0.001000 (rank : 133)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	126	Target Neighborhood Hits	910	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.