Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : BLM_HUMAN

For an explanation of this page, click here

BLM_HUMAN
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BLM_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	148
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	0 (rank : 2)	NC score	0.989856 (rank : 2)
Query Neighborhood Hits	148	Target Neighborhood Hits	108	Shared Neighborhood Hits	79
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RECQ1_HUMAN
θ value	2.15048e-102 (rank : 3)	NC score	0.921464 (rank : 3)
Query Neighborhood Hits	148	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
θ value	1.06727e-101 (rank : 4)	NC score	0.921356 (rank : 4)
Query Neighborhood Hits	148	Target Neighborhood Hits	95	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ5_HUMAN
θ value	5.33382e-77 (rank : 5)	NC score	0.846993 (rank : 5)
Query Neighborhood Hits	148	Target Neighborhood Hits	390	Shared Neighborhood Hits	73
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_HUMAN
θ value	1.61343e-57 (rank : 6)	NC score	0.846533 (rank : 6)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	76
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
θ value	2.18062e-54 (rank : 7)	NC score	0.814468 (rank : 8)
Query Neighborhood Hits	148	Target Neighborhood Hits	295	Shared Neighborhood Hits	78
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ4_MOUSE
θ value	8.59492e-43 (rank : 8)	NC score	0.811873 (rank : 9)
Query Neighborhood Hits	148	Target Neighborhood Hits	206	Shared Neighborhood Hits	75
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ4_HUMAN
θ value	2.11701e-41 (rank : 9)	NC score	0.817840 (rank : 7)
Query Neighborhood Hits	148	Target Neighborhood Hits	177	Shared Neighborhood Hits	75
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

DDX47_HUMAN
θ value	1.58096e-12 (rank : 10)	NC score	0.514926 (rank : 22)
Query Neighborhood Hits	148	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX5_MOUSE
θ value	2.69671e-12 (rank : 11)	NC score	0.546613 (rank : 10)
Query Neighborhood Hits	148	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX17_HUMAN
θ value	4.59992e-12 (rank : 12)	NC score	0.546512 (rank : 12)
Query Neighborhood Hits	148	Target Neighborhood Hits	104	Shared Neighborhood Hits	73
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	4.59992e-12 (rank : 13)	NC score	0.546573 (rank : 11)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	73
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX47_MOUSE
θ value	4.59992e-12 (rank : 14)	NC score	0.513968 (rank : 23)
Query Neighborhood Hits	148	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX5_HUMAN
θ value	4.59992e-12 (rank : 15)	NC score	0.545600 (rank : 13)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX6_HUMAN
θ value	2.52405e-10 (rank : 16)	NC score	0.526594 (rank : 16)
Query Neighborhood Hits	148	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	2.52405e-10 (rank : 17)	NC score	0.526490 (rank : 17)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	73
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX23_HUMAN
θ value	5.62301e-10 (rank : 18)	NC score	0.512915 (rank : 24)
Query Neighborhood Hits	148	Target Neighborhood Hits	486	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX46_HUMAN
θ value	4.76016e-09 (rank : 19)	NC score	0.528471 (rank : 14)
Query Neighborhood Hits	148	Target Neighborhood Hits	357	Shared Neighborhood Hits	82
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	4.76016e-09 (rank : 20)	NC score	0.527467 (rank : 15)
Query Neighborhood Hits	148	Target Neighborhood Hits	358	Shared Neighborhood Hits	85
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX21_HUMAN
θ value	5.26297e-08 (rank : 21)	NC score	0.515882 (rank : 20)
Query Neighborhood Hits	148	Target Neighborhood Hits	308	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX49_HUMAN
θ value	1.53129e-07 (rank : 22)	NC score	0.511009 (rank : 28)
Query Neighborhood Hits	148	Target Neighborhood Hits	223	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX50_HUMAN
θ value	2.61198e-07 (rank : 23)	NC score	0.522689 (rank : 18)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	3.41135e-07 (rank : 24)	NC score	0.522554 (rank : 19)
Query Neighborhood Hits	148	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX49_MOUSE
θ value	9.92553e-07 (rank : 25)	NC score	0.512705 (rank : 26)
Query Neighborhood Hits	148	Target Neighborhood Hits	119	Shared Neighborhood Hits	76
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX21_MOUSE
θ value	1.29631e-06 (rank : 26)	NC score	0.507216 (rank : 29)
Query Neighborhood Hits	148	Target Neighborhood Hits	350	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX39_HUMAN
θ value	1.69304e-06 (rank : 27)	NC score	0.495236 (rank : 39)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX3X_HUMAN
θ value	1.69304e-06 (rank : 28)	NC score	0.505996 (rank : 31)
Query Neighborhood Hits	148	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	1.69304e-06 (rank : 29)	NC score	0.507167 (rank : 30)
Query Neighborhood Hits	148	Target Neighborhood Hits	117	Shared Neighborhood Hits	74
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_HUMAN
θ value	1.69304e-06 (rank : 30)	NC score	0.505444 (rank : 32)
Query Neighborhood Hits	148	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX48_HUMAN
θ value	1.69304e-06 (rank : 31)	NC score	0.503443 (rank : 34)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

PL10_MOUSE
θ value	1.69304e-06 (rank : 32)	NC score	0.504823 (rank : 33)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	74
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX48_MOUSE
θ value	2.21117e-06 (rank : 33)	NC score	0.503036 (rank : 35)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX10_HUMAN
θ value	8.40245e-06 (rank : 34)	NC score	0.482329 (rank : 51)
Query Neighborhood Hits	148	Target Neighborhood Hits	210	Shared Neighborhood Hits	77
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	8.40245e-06 (rank : 35)	NC score	0.480962 (rank : 53)
Query Neighborhood Hits	148	Target Neighborhood Hits	233	Shared Neighborhood Hits	76
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX54_MOUSE
θ value	8.40245e-06 (rank : 36)	NC score	0.485367 (rank : 48)
Query Neighborhood Hits	148	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX39_MOUSE
θ value	1.09739e-05 (rank : 37)	NC score	0.492328 (rank : 40)
Query Neighborhood Hits	148	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX41_HUMAN
θ value	2.44474e-05 (rank : 38)	NC score	0.514976 (rank : 21)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

UAP56_HUMAN
θ value	4.1701e-05 (rank : 39)	NC score	0.485569 (rank : 46)
Query Neighborhood Hits	148	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	4.1701e-05 (rank : 40)	NC score	0.485451 (rank : 47)
Query Neighborhood Hits	148	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX41_MOUSE
θ value	5.44631e-05 (rank : 41)	NC score	0.512087 (rank : 27)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	73
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

IF4A2_HUMAN
θ value	5.44631e-05 (rank : 42)	NC score	0.490276 (rank : 41)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	5.44631e-05 (rank : 43)	NC score	0.490276 (rank : 42)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX20_MOUSE
θ value	9.29e-05 (rank : 44)	NC score	0.463321 (rank : 62)
Query Neighborhood Hits	148	Target Neighborhood Hits	177	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX1_MOUSE
θ value	0.000121331 (rank : 45)	NC score	0.467023 (rank : 59)
Query Neighborhood Hits	148	Target Neighborhood Hits	112	Shared Neighborhood Hits	72
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

IF4A1_HUMAN
θ value	0.000121331 (rank : 46)	NC score	0.488177 (rank : 43)
Query Neighborhood Hits	148	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	0.000121331 (rank : 47)	NC score	0.488177 (rank : 44)
Query Neighborhood Hits	148	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX18_HUMAN
θ value	0.000158464 (rank : 48)	NC score	0.452982 (rank : 64)
Query Neighborhood Hits	148	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX3Y_MOUSE
θ value	0.000158464 (rank : 49)	NC score	0.498201 (rank : 38)
Query Neighborhood Hits	148	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX20_HUMAN
θ value	0.00020696 (rank : 50)	NC score	0.466126 (rank : 60)
Query Neighborhood Hits	148	Target Neighborhood Hits	121	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX1_HUMAN
θ value	0.000270298 (rank : 51)	NC score	0.464140 (rank : 61)
Query Neighborhood Hits	148	Target Neighborhood Hits	110	Shared Neighborhood Hits	72
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX54_HUMAN
θ value	0.000461057 (rank : 52)	NC score	0.479116 (rank : 56)
Query Neighborhood Hits	148	Target Neighborhood Hits	170	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX4_HUMAN
θ value	0.000786445 (rank : 53)	NC score	0.485755 (rank : 45)
Query Neighborhood Hits	148	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	0.000786445 (rank : 54)	NC score	0.485161 (rank : 49)
Query Neighborhood Hits	148	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX43_HUMAN
θ value	0.00175202 (rank : 55)	NC score	0.512886 (rank : 25)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX52_HUMAN
θ value	0.00175202 (rank : 56)	NC score	0.500198 (rank : 37)
Query Neighborhood Hits	148	Target Neighborhood Hits	107	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
θ value	0.00175202 (rank : 57)	NC score	0.500324 (rank : 36)
Query Neighborhood Hits	148	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX24_MOUSE
θ value	0.00390308 (rank : 58)	NC score	0.476170 (rank : 57)
Query Neighborhood Hits	148	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX31_HUMAN
θ value	0.00390308 (rank : 59)	NC score	0.479349 (rank : 55)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX24_HUMAN
θ value	0.00509761 (rank : 60)	NC score	0.473534 (rank : 58)
Query Neighborhood Hits	148	Target Neighborhood Hits	190	Shared Neighborhood Hits	77
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX27_MOUSE
θ value	0.0148317 (rank : 61)	NC score	0.484093 (rank : 50)
Query Neighborhood Hits	148	Target Neighborhood Hits	174	Shared Neighborhood Hits	76
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
θ value	0.0193708 (rank : 62)	NC score	0.482016 (rank : 52)
Query Neighborhood Hits	148	Target Neighborhood Hits	197	Shared Neighborhood Hits	77
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

U520_HUMAN
θ value	0.0252991 (rank : 63)	NC score	0.155505 (rank : 84)
Query Neighborhood Hits	148	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

DDX28_MOUSE
θ value	0.0563607 (rank : 64)	NC score	0.459948 (rank : 63)
Query Neighborhood Hits	148	Target Neighborhood Hits	112	Shared Neighborhood Hits	74
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX51_HUMAN
θ value	0.0563607 (rank : 65)	NC score	0.449148 (rank : 65)
Query Neighborhood Hits	148	Target Neighborhood Hits	332	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

A4_MOUSE
θ value	0.0961366 (rank : 66)	NC score	0.033073 (rank : 101)
Query Neighborhood Hits	148	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

DDX18_MOUSE
θ value	0.0961366 (rank : 67)	NC score	0.439119 (rank : 68)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

TRIPC_HUMAN
θ value	0.0961366 (rank : 68)	NC score	0.026035 (rank : 112)
Query Neighborhood Hits	148	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

CENPJ_HUMAN
θ value	0.125558 (rank : 69)	NC score	0.032986 (rank : 102)
Query Neighborhood Hits	148	Target Neighborhood Hits	721	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

DDX25_HUMAN
θ value	0.125558 (rank : 70)	NC score	0.423659 (rank : 74)
Query Neighborhood Hits	148	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DSPP_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.028782 (rank : 107)
Query Neighborhood Hits	148	Target Neighborhood Hits	645	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GAK18_HUMAN
θ value	0.163984 (rank : 72)	NC score	0.015102 (rank : 135)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

DDX28_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.447416 (rank : 66)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

ANR12_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.015507 (rank : 130)
Query Neighborhood Hits	148	Target Neighborhood Hits	1081	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

DMP1_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.052335 (rank : 97)
Query Neighborhood Hits	148	Target Neighborhood Hits	491	Shared Neighborhood Hits	32
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DD19A_HUMAN
θ value	0.365318 (rank : 76)	NC score	0.428859 (rank : 70)
Query Neighborhood Hits	148	Target Neighborhood Hits	107	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
θ value	0.365318 (rank : 77)	NC score	0.428368 (rank : 71)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

RGP2_HUMAN
θ value	0.365318 (rank : 78)	NC score	0.024281 (rank : 116)
Query Neighborhood Hits	148	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

A4_HUMAN
θ value	0.47712 (rank : 79)	NC score	0.029304 (rank : 106)
Query Neighborhood Hits	148	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

IF2P_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.026153 (rank : 110)
Query Neighborhood Hits	148	Target Neighborhood Hits	889	Shared Neighborhood Hits	32
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MYST4_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.027418 (rank : 109)
Query Neighborhood Hits	148	Target Neighborhood Hits	671	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TAXB1_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.010433 (rank : 150)
Query Neighborhood Hits	148	Target Neighborhood Hits	886	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TP53B_MOUSE
θ value	0.62314 (rank : 83)	NC score	0.029615 (rank : 104)
Query Neighborhood Hits	148	Target Neighborhood Hits	644	Shared Neighborhood Hits	20
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

UBP10_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.018019 (rank : 123)
Query Neighborhood Hits	148	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

AF9_HUMAN
θ value	0.813845 (rank : 85)	NC score	0.028581 (rank : 108)
Query Neighborhood Hits	148	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

DAB1_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.024816 (rank : 114)
Query Neighborhood Hits	148	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DD19A_MOUSE
θ value	0.813845 (rank : 87)	NC score	0.426645 (rank : 73)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	71
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

HTSF1_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.023918 (rank : 117)
Query Neighborhood Hits	148	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

MDC1_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.016284 (rank : 126)
Query Neighborhood Hits	148	Target Neighborhood Hits	1446	Shared Neighborhood Hits	33
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

P_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.025992 (rank : 113)
Query Neighborhood Hits	148	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q04671, Q15211, Q15212, Q96EN1, Q9UMI5	Gene names	OCA2, P
Domain Architecture
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog).

MCM2_MOUSE
θ value	1.06291 (rank : 91)	NC score	0.015364 (rank : 131)
Query Neighborhood Hits	148	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P97310, O08971, O89057, Q8C2R0	Gene names	Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

TSCC1_MOUSE
θ value	1.38821 (rank : 92)	NC score	0.033223 (rank : 100)
Query Neighborhood Hits	148	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0G5	Gene names	Tssc1
Domain Architecture	No domain graphic available
Description	Protein TSSC1.

TSSC1_HUMAN
θ value	1.38821 (rank : 93)	NC score	0.033646 (rank : 99)
Query Neighborhood Hits	148	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q53HC9, O43179, Q53S19, Q53SG2	Gene names	TSSC1
Domain Architecture	No domain graphic available
Description	Protein TSSC1 (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) (Tumor-suppressing STF cDNA 1 protein).

CING_MOUSE
θ value	1.81305 (rank : 94)	NC score	0.008018 (rank : 156)
Query Neighborhood Hits	148	Target Neighborhood Hits	1432	Shared Neighborhood Hits	25
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

FILA_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.031531 (rank : 103)
Query Neighborhood Hits	148	Target Neighborhood Hits	685	Shared Neighborhood Hits	19
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

KMHN1_MOUSE
θ value	1.81305 (rank : 96)	NC score	0.013899 (rank : 139)
Query Neighborhood Hits	148	Target Neighborhood Hits	949	Shared Neighborhood Hits	18
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

KS6C1_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.001807 (rank : 169)
Query Neighborhood Hits	148	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

MYST3_MOUSE
θ value	1.81305 (rank : 98)	NC score	0.023181 (rank : 118)
Query Neighborhood Hits	148	Target Neighborhood Hits	688	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.020714 (rank : 119)
Query Neighborhood Hits	148	Target Neighborhood Hits	416	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

AKAP9_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.006659 (rank : 162)
Query Neighborhood Hits	148	Target Neighborhood Hits	1710	Shared Neighborhood Hits	26
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

EMSY_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.024348 (rank : 115)
Query Neighborhood Hits	148	Target Neighborhood Hits	294	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

PCLO_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.015108 (rank : 134)
Query Neighborhood Hits	148	Target Neighborhood Hits	2046	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ZF106_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.011392 (rank : 147)
Query Neighborhood Hits	148	Target Neighborhood Hits	470	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ATF2_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.015611 (rank : 129)
Query Neighborhood Hits	148	Target Neighborhood Hits	402	Shared Neighborhood Hits	9
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	3.0926 (rank : 105)	NC score	0.015272 (rank : 132)
Query Neighborhood Hits	148	Target Neighborhood Hits	397	Shared Neighborhood Hits	9
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

HPS5_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.014990 (rank : 136)
Query Neighborhood Hits	148	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPZ3, O95942, Q8N4U0	Gene names	HPS5, AIBP63, KIAA1017
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein (Alpha-integrin-binding protein 63) (Ruby-eye protein 2 homolog) (Ru2).

K1914_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.016175 (rank : 127)
Query Neighborhood Hits	148	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

NCOA7_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.013744 (rank : 140)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q6DFV7, Q3TAR1, Q3UNB3, Q66K05, Q6ZQM4, Q8BJ15, Q8BJ39	Gene names	Ncoa7
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7.

UTRO_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.005324 (rank : 166)
Query Neighborhood Hits	148	Target Neighborhood Hits	960	Shared Neighborhood Hits	21
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

BRE1A_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.007583 (rank : 157)
Query Neighborhood Hits	148	Target Neighborhood Hits	1071	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

DDX51_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.444073 (rank : 67)
Query Neighborhood Hits	148	Target Neighborhood Hits	130	Shared Neighborhood Hits	76
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

IF5_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.015246 (rank : 133)
Query Neighborhood Hits	148	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

MSH6_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.009390 (rank : 154)
Query Neighborhood Hits	148	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

PELP1_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.018586 (rank : 121)
Query Neighborhood Hits	148	Target Neighborhood Hits	596	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PHC1_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.010174 (rank : 152)
Query Neighborhood Hits	148	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

RBBP6_MOUSE
θ value	4.03905 (rank : 116)	NC score	0.026057 (rank : 111)
Query Neighborhood Hits	148	Target Neighborhood Hits	1014	Shared Neighborhood Hits	31
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SMRC2_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.017893 (rank : 125)
Query Neighborhood Hits	148	Target Neighborhood Hits	499	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

STAM1_MOUSE
θ value	4.03905 (rank : 118)	NC score	0.007456 (rank : 158)
Query Neighborhood Hits	148	Target Neighborhood Hits	273	Shared Neighborhood Hits	6
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TXD13_MOUSE
θ value	4.03905 (rank : 119)	NC score	0.014305 (rank : 137)
Query Neighborhood Hits	148	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

DAXX_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.014191 (rank : 138)
Query Neighborhood Hits	148	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DDX55_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.427853 (rank : 72)
Query Neighborhood Hits	148	Target Neighborhood Hits	122	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.429496 (rank : 69)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

FBX7_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.029389 (rank : 105)
Query Neighborhood Hits	148	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3I1, Q5TGC4, Q96HM6, Q9UF21, Q9UKT2	Gene names	FBXO7, FBX7
Domain Architecture	No domain graphic available
Description	F-box only protein 7.

SP100_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.006812 (rank : 161)
Query Neighborhood Hits	148	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

DAB1_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.017906 (rank : 124)
Query Neighborhood Hits	148	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

FA44A_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.015667 (rank : 128)
Query Neighborhood Hits	148	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

LZTS1_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.007011 (rank : 160)
Query Neighborhood Hits	148	Target Neighborhood Hits	540	Shared Neighborhood Hits	11
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MCM2_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.011448 (rank : 146)
Query Neighborhood Hits	148	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7	Gene names	MCM2, BM28, CDCL1, KIAA0030
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

RFC1_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.011498 (rank : 145)
Query Neighborhood Hits	148	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RIR1_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.010397 (rank : 151)
Query Neighborhood Hits	148	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P23921, Q9UNN2	Gene names	RRM1, RR1
Domain Architecture
Description	Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase M1 subunit) (Ribonucleotide reductase large chain).

SF3B1_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.011829 (rank : 144)
Query Neighborhood Hits	148	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.011839 (rank : 143)
Query Neighborhood Hits	148	Target Neighborhood Hits	352	Shared Neighborhood Hits	6
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

STAM1_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.006089 (rank : 165)
Query Neighborhood Hits	148	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TF2AY_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.012213 (rank : 142)
Query Neighborhood Hits	148	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4I4, Q99PM2, Q9DAF4	Gene names	Gtf2a1lf, Alf
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

TGFR2_MOUSE
θ value	6.88961 (rank : 135)	NC score	-0.003236 (rank : 170)
Query Neighborhood Hits	148	Target Neighborhood Hits	748	Shared Neighborhood Hits	2
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

TXND2_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.040078 (rank : 98)
Query Neighborhood Hits	148	Target Neighborhood Hits	828	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

XKR5_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.008257 (rank : 155)
Query Neighborhood Hits	148	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH66	Gene names	Xkr5, Xrg5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

ERGI3_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.007352 (rank : 159)
Query Neighborhood Hits	148	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y282, Q6ZWP7, Q9H276, Q9P1L3	Gene names	ERGIC3, C20orf47, ERV46, SDBCAG84
Domain Architecture	No domain graphic available
Description	Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84).

GOGA4_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.009839 (rank : 153)
Query Neighborhood Hits	148	Target Neighborhood Hits	2034	Shared Neighborhood Hits	39
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGB1_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.012500 (rank : 141)
Query Neighborhood Hits	148	Target Neighborhood Hits	2297	Shared Neighborhood Hits	43
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NC6IP_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.018299 (rank : 122)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

P55G_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.011149 (rank : 148)
Query Neighborhood Hits	148	Target Neighborhood Hits	451	Shared Neighborhood Hits	12
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.011078 (rank : 149)
Query Neighborhood Hits	148	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PRG3_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.006535 (rank : 164)
Query Neighborhood Hits	148	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

RIMS2_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.003865 (rank : 168)
Query Neighborhood Hits	148	Target Neighborhood Hits	342	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SHAN2_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.004695 (rank : 167)
Query Neighborhood Hits	148	Target Neighborhood Hits	346	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SMRC2_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.019843 (rank : 120)
Query Neighborhood Hits	148	Target Neighborhood Hits	487	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SVIL_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.006554 (rank : 163)
Query Neighborhood Hits	148	Target Neighborhood Hits	232	Shared Neighborhood Hits	11
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

CC026_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.087083 (rank : 88)
Query Neighborhood Hits	148	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.061270 (rank : 93)
Query Neighborhood Hits	148	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

DDX25_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.416883 (rank : 75)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX53_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.480295 (rank : 54)
Query Neighborhood Hits	148	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX56_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.409738 (rank : 76)
Query Neighborhood Hits	148	Target Neighborhood Hits	77	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.409502 (rank : 77)
Query Neighborhood Hits	148	Target Neighborhood Hits	87	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX58_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.067117 (rank : 91)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.086595 (rank : 89)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DICER_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.189548 (rank : 81)
Query Neighborhood Hits	148	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.189853 (rank : 80)
Query Neighborhood Hits	148	Target Neighborhood Hits	140	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

EXDL2_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.062277 (rank : 92)
Query Neighborhood Hits	148	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

EXDL2_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.060337 (rank : 94)
Query Neighborhood Hits	148	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

FANCM_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.192300 (rank : 78)
Query Neighborhood Hits	148	Target Neighborhood Hits	210	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.191827 (rank : 79)
Query Neighborhood Hits	148	Target Neighborhood Hits	177	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

HELC1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.111121 (rank : 87)
Query Neighborhood Hits	148	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

IFIH1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.158114 (rank : 82)
Query Neighborhood Hits	148	Target Neighborhood Hits	96	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.153707 (rank : 86)
Query Neighborhood Hits	148	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LGP2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.156142 (rank : 83)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	62
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

LGP2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.154673 (rank : 85)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	60
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

SK2L2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.055200 (rank : 95)
Query Neighborhood Hits	148	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.052659 (rank : 96)
Query Neighborhood Hits	148	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SKIV2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.067791 (rank : 90)
Query Neighborhood Hits	148	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

Hits sorted by NC score

BLM_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	148
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
NC score	0.989856 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	148	Target Neighborhood Hits	108	Shared Neighborhood Hits	79
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RECQ1_HUMAN
NC score	0.921464 (rank : 3)	θ value	2.15048e-102 (rank : 3)
Query Neighborhood Hits	148	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.921356 (rank : 4)	θ value	1.06727e-101 (rank : 4)
Query Neighborhood Hits	148	Target Neighborhood Hits	95	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ5_HUMAN
NC score	0.846993 (rank : 5)	θ value	5.33382e-77 (rank : 5)
Query Neighborhood Hits	148	Target Neighborhood Hits	390	Shared Neighborhood Hits	73
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_HUMAN
NC score	0.846533 (rank : 6)	θ value	1.61343e-57 (rank : 6)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	76
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ4_HUMAN
NC score	0.817840 (rank : 7)	θ value	2.11701e-41 (rank : 9)
Query Neighborhood Hits	148	Target Neighborhood Hits	177	Shared Neighborhood Hits	75
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

WRN_MOUSE
NC score	0.814468 (rank : 8)	θ value	2.18062e-54 (rank : 7)
Query Neighborhood Hits	148	Target Neighborhood Hits	295	Shared Neighborhood Hits	78
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ4_MOUSE
NC score	0.811873 (rank : 9)	θ value	8.59492e-43 (rank : 8)
Query Neighborhood Hits	148	Target Neighborhood Hits	206	Shared Neighborhood Hits	75
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DDX5_MOUSE
NC score	0.546613 (rank : 10)	θ value	2.69671e-12 (rank : 11)
Query Neighborhood Hits	148	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX17_MOUSE
NC score	0.546573 (rank : 11)	θ value	4.59992e-12 (rank : 13)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	73
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.546512 (rank : 12)	θ value	4.59992e-12 (rank : 12)
Query Neighborhood Hits	148	Target Neighborhood Hits	104	Shared Neighborhood Hits	73
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX5_HUMAN
NC score	0.545600 (rank : 13)	θ value	4.59992e-12 (rank : 15)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX46_HUMAN
NC score	0.528471 (rank : 14)	θ value	4.76016e-09 (rank : 19)
Query Neighborhood Hits	148	Target Neighborhood Hits	357	Shared Neighborhood Hits	82
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
NC score	0.527467 (rank : 15)	θ value	4.76016e-09 (rank : 20)
Query Neighborhood Hits	148	Target Neighborhood Hits	358	Shared Neighborhood Hits	85
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX6_HUMAN
NC score	0.526594 (rank : 16)	θ value	2.52405e-10 (rank : 16)
Query Neighborhood Hits	148	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.526490 (rank : 17)	θ value	2.52405e-10 (rank : 17)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	73
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX50_HUMAN
NC score	0.522689 (rank : 18)	θ value	2.61198e-07 (rank : 23)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.522554 (rank : 19)	θ value	3.41135e-07 (rank : 24)
Query Neighborhood Hits	148	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX21_HUMAN
NC score	0.515882 (rank : 20)	θ value	5.26297e-08 (rank : 21)
Query Neighborhood Hits	148	Target Neighborhood Hits	308	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX41_HUMAN
NC score	0.514976 (rank : 21)	θ value	2.44474e-05 (rank : 38)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX47_HUMAN
NC score	0.514926 (rank : 22)	θ value	1.58096e-12 (rank : 10)
Query Neighborhood Hits	148	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
NC score	0.513968 (rank : 23)	θ value	4.59992e-12 (rank : 14)
Query Neighborhood Hits	148	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX23_HUMAN
NC score	0.512915 (rank : 24)	θ value	5.62301e-10 (rank : 18)
Query Neighborhood Hits	148	Target Neighborhood Hits	486	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX43_HUMAN
NC score	0.512886 (rank : 25)	θ value	0.00175202 (rank : 55)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX49_MOUSE
NC score	0.512705 (rank : 26)	θ value	9.92553e-07 (rank : 25)
Query Neighborhood Hits	148	Target Neighborhood Hits	119	Shared Neighborhood Hits	76
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX41_MOUSE
NC score	0.512087 (rank : 27)	θ value	5.44631e-05 (rank : 41)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	73
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX49_HUMAN
NC score	0.511009 (rank : 28)	θ value	1.53129e-07 (rank : 22)
Query Neighborhood Hits	148	Target Neighborhood Hits	223	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX21_MOUSE
NC score	0.507216 (rank : 29)	θ value	1.29631e-06 (rank : 26)
Query Neighborhood Hits	148	Target Neighborhood Hits	350	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX3X_MOUSE
NC score	0.507167 (rank : 30)	θ value	1.69304e-06 (rank : 29)
Query Neighborhood Hits	148	Target Neighborhood Hits	117	Shared Neighborhood Hits	74
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3X_HUMAN
NC score	0.505996 (rank : 31)	θ value	1.69304e-06 (rank : 28)
Query Neighborhood Hits	148	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_HUMAN
NC score	0.505444 (rank : 32)	θ value	1.69304e-06 (rank : 30)
Query Neighborhood Hits	148	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

PL10_MOUSE
NC score	0.504823 (rank : 33)	θ value	1.69304e-06 (rank : 32)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	74
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX48_HUMAN
NC score	0.503443 (rank : 34)	θ value	1.69304e-06 (rank : 31)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.503036 (rank : 35)	θ value	2.21117e-06 (rank : 33)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX52_MOUSE
NC score	0.500324 (rank : 36)	θ value	0.00175202 (rank : 57)
Query Neighborhood Hits	148	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_HUMAN
NC score	0.500198 (rank : 37)	θ value	0.00175202 (rank : 56)
Query Neighborhood Hits	148	Target Neighborhood Hits	107	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX3Y_MOUSE
NC score	0.498201 (rank : 38)	θ value	0.000158464 (rank : 49)
Query Neighborhood Hits	148	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX39_HUMAN
NC score	0.495236 (rank : 39)	θ value	1.69304e-06 (rank : 27)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
NC score	0.492328 (rank : 40)	θ value	1.09739e-05 (rank : 37)
Query Neighborhood Hits	148	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

IF4A2_HUMAN
NC score	0.490276 (rank : 41)	θ value	5.44631e-05 (rank : 42)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.490276 (rank : 42)	θ value	5.44631e-05 (rank : 43)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A1_HUMAN
NC score	0.488177 (rank : 43)	θ value	0.000121331 (rank : 46)
Query Neighborhood Hits	148	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.488177 (rank : 44)	θ value	0.000121331 (rank : 47)
Query Neighborhood Hits	148	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX4_HUMAN
NC score	0.485755 (rank : 45)	θ value	0.000786445 (rank : 53)
Query Neighborhood Hits	148	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

UAP56_HUMAN
NC score	0.485569 (rank : 46)	θ value	4.1701e-05 (rank : 39)
Query Neighborhood Hits	148	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.485451 (rank : 47)	θ value	4.1701e-05 (rank : 40)
Query Neighborhood Hits	148	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX54_MOUSE
NC score	0.485367 (rank : 48)	θ value	8.40245e-06 (rank : 36)
Query Neighborhood Hits	148	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX4_MOUSE
NC score	0.485161 (rank : 49)	θ value	0.000786445 (rank : 54)
Query Neighborhood Hits	148	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX27_MOUSE
NC score	0.484093 (rank : 50)	θ value	0.0148317 (rank : 61)
Query Neighborhood Hits	148	Target Neighborhood Hits	174	Shared Neighborhood Hits	76
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX10_HUMAN
NC score	0.482329 (rank : 51)	θ value	8.40245e-06 (rank : 34)
Query Neighborhood Hits	148	Target Neighborhood Hits	210	Shared Neighborhood Hits	77
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX27_HUMAN
NC score	0.482016 (rank : 52)	θ value	0.0193708 (rank : 62)
Query Neighborhood Hits	148	Target Neighborhood Hits	197	Shared Neighborhood Hits	77
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX10_MOUSE
NC score	0.480962 (rank : 53)	θ value	8.40245e-06 (rank : 35)
Query Neighborhood Hits	148	Target Neighborhood Hits	233	Shared Neighborhood Hits	76
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX53_HUMAN
NC score	0.480295 (rank : 54)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	148	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX31_HUMAN
NC score	0.479349 (rank : 55)	θ value	0.00390308 (rank : 59)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX54_HUMAN
NC score	0.479116 (rank : 56)	θ value	0.000461057 (rank : 52)
Query Neighborhood Hits	148	Target Neighborhood Hits	170	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX24_MOUSE
NC score	0.476170 (rank : 57)	θ value	0.00390308 (rank : 58)
Query Neighborhood Hits	148	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
NC score	0.473534 (rank : 58)	θ value	0.00509761 (rank : 60)
Query Neighborhood Hits	148	Target Neighborhood Hits	190	Shared Neighborhood Hits	77
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX1_MOUSE
NC score	0.467023 (rank : 59)	θ value	0.000121331 (rank : 45)
Query Neighborhood Hits	148	Target Neighborhood Hits	112	Shared Neighborhood Hits	72
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX20_HUMAN
NC score	0.466126 (rank : 60)	θ value	0.00020696 (rank : 50)
Query Neighborhood Hits	148	Target Neighborhood Hits	121	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX1_HUMAN
NC score	0.464140 (rank : 61)	θ value	0.000270298 (rank : 51)
Query Neighborhood Hits	148	Target Neighborhood Hits	110	Shared Neighborhood Hits	72
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX20_MOUSE
NC score	0.463321 (rank : 62)	θ value	9.29e-05 (rank : 44)
Query Neighborhood Hits	148	Target Neighborhood Hits	177	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX28_MOUSE
NC score	0.459948 (rank : 63)	θ value	0.0563607 (rank : 64)
Query Neighborhood Hits	148	Target Neighborhood Hits	112	Shared Neighborhood Hits	74
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX18_HUMAN
NC score	0.452982 (rank : 64)	θ value	0.000158464 (rank : 48)
Query Neighborhood Hits	148	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX51_HUMAN
NC score	0.449148 (rank : 65)	θ value	0.0563607 (rank : 65)
Query Neighborhood Hits	148	Target Neighborhood Hits	332	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX28_HUMAN
NC score	0.447416 (rank : 66)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX51_MOUSE
NC score	0.444073 (rank : 67)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	148	Target Neighborhood Hits	130	Shared Neighborhood Hits	76
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX18_MOUSE
NC score	0.439119 (rank : 68)	θ value	0.0961366 (rank : 67)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX55_MOUSE
NC score	0.429496 (rank : 69)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DD19A_HUMAN
NC score	0.428859 (rank : 70)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	148	Target Neighborhood Hits	107	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.428368 (rank : 71)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX55_HUMAN
NC score	0.427853 (rank : 72)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	148	Target Neighborhood Hits	122	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DD19A_MOUSE
NC score	0.426645 (rank : 73)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	71
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_HUMAN
NC score	0.423659 (rank : 74)	θ value	0.125558 (rank : 70)
Query Neighborhood Hits	148	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
NC score	0.416883 (rank : 75)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX56_HUMAN
NC score	0.409738 (rank : 76)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	148	Target Neighborhood Hits	77	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
NC score	0.409502 (rank : 77)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	148	Target Neighborhood Hits	87	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

FANCM_HUMAN
NC score	0.192300 (rank : 78)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	148	Target Neighborhood Hits	210	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.191827 (rank : 79)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	148	Target Neighborhood Hits	177	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_MOUSE
NC score	0.189853 (rank : 80)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	148	Target Neighborhood Hits	140	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.189548 (rank : 81)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	148	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

IFIH1_HUMAN
NC score	0.158114 (rank : 82)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	148	Target Neighborhood Hits	96	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
NC score	0.156142 (rank : 83)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	62
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

U520_HUMAN
NC score	0.155505 (rank : 84)	θ value	0.0252991 (rank : 63)
Query Neighborhood Hits	148	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

LGP2_MOUSE
NC score	0.154673 (rank : 85)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	60
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

IFIH1_MOUSE
NC score	0.153707 (rank : 86)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	148	Target Neighborhood Hits	126	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

HELC1_HUMAN
NC score	0.111121 (rank : 87)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	148	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

CC026_HUMAN
NC score	0.087083 (rank : 88)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	148	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX58_MOUSE
NC score	0.086595 (rank : 89)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

SKIV2_HUMAN
NC score	0.067791 (rank : 90)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	148	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

DDX58_HUMAN
NC score	0.067117 (rank : 91)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

EXDL2_HUMAN
NC score	0.062277 (rank : 92)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	148	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVH0, Q8N3D3	Gene names	EXDL2, C14orf114
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

CC026_MOUSE
NC score	0.061270 (rank : 93)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	148	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

EXDL2_MOUSE
NC score	0.060337 (rank : 94)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	148	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

SK2L2_HUMAN
NC score	0.055200 (rank : 95)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	148	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_MOUSE
NC score	0.052659 (rank : 96)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	148	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

DMP1_HUMAN
NC score	0.052335 (rank : 97)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	148	Target Neighborhood Hits	491	Shared Neighborhood Hits	32
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TXND2_MOUSE
NC score	0.040078 (rank : 98)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	148	Target Neighborhood Hits	828	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TSSC1_HUMAN
NC score	0.033646 (rank : 99)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	148	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q53HC9, O43179, Q53S19, Q53SG2	Gene names	TSSC1
Domain Architecture	No domain graphic available
Description	Protein TSSC1 (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein) (Tumor-suppressing STF cDNA 1 protein).

TSCC1_MOUSE
NC score	0.033223 (rank : 100)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	148	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0G5	Gene names	Tssc1
Domain Architecture	No domain graphic available
Description	Protein TSSC1.

A4_MOUSE
NC score	0.033073 (rank : 101)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	148	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CENPJ_HUMAN
NC score	0.032986 (rank : 102)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	148	Target Neighborhood Hits	721	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

FILA_HUMAN
NC score	0.031531 (rank : 103)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	148	Target Neighborhood Hits	685	Shared Neighborhood Hits	19
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

TP53B_MOUSE
NC score	0.029615 (rank : 104)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	148	Target Neighborhood Hits	644	Shared Neighborhood Hits	20
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

FBX7_HUMAN
NC score	0.029389 (rank : 105)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	148	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3I1, Q5TGC4, Q96HM6, Q9UF21, Q9UKT2	Gene names	FBXO7, FBX7
Domain Architecture	No domain graphic available
Description	F-box only protein 7.

A4_HUMAN
NC score	0.029304 (rank : 106)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	148	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

DSPP_HUMAN
NC score	0.028782 (rank : 107)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	148	Target Neighborhood Hits	645	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

AF9_HUMAN
NC score	0.028581 (rank : 108)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	148	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

MYST4_HUMAN
NC score	0.027418 (rank : 109)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	148	Target Neighborhood Hits	671	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

IF2P_HUMAN
NC score	0.026153 (rank : 110)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	148	Target Neighborhood Hits	889	Shared Neighborhood Hits	32
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

RBBP6_MOUSE
NC score	0.026057 (rank : 111)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	148	Target Neighborhood Hits	1014	Shared Neighborhood Hits	31
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRIPC_HUMAN
NC score	0.026035 (rank : 112)	θ value	0.0961366 (rank : 68)
Query Neighborhood Hits	148	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

P_HUMAN
NC score	0.025992 (rank : 113)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	148	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q04671, Q15211, Q15212, Q96EN1, Q9UMI5	Gene names	OCA2, P
Domain Architecture
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog).

DAB1_HUMAN
NC score	0.024816 (rank : 114)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	148	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

EMSY_MOUSE
NC score	0.024348 (rank : 115)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	148	Target Neighborhood Hits	294	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

RGP2_HUMAN
NC score	0.024281 (rank : 116)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	148	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

HTSF1_HUMAN
NC score	0.023918 (rank : 117)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	148	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

MYST3_MOUSE
NC score	0.023181 (rank : 118)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	148	Target Neighborhood Hits	688	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_MOUSE
NC score	0.020714 (rank : 119)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	148	Target Neighborhood Hits	416	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

SMRC2_MOUSE
NC score	0.019843 (rank : 120)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	148	Target Neighborhood Hits	487	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PELP1_HUMAN
NC score	0.018586 (rank : 121)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	148	Target Neighborhood Hits	596	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

NC6IP_HUMAN
NC score	0.018299 (rank : 122)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RS0, Q5GH23, Q8TDG9, Q96QU3, Q9H5V3	Gene names	NCOA6IP, PIMT
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT) (CLL-associated antigen KW-2) (Hepatocellular carcinoma-associated antigen 137) (HCA137).

UBP10_HUMAN
NC score	0.018019 (rank : 123)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	148	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

DAB1_MOUSE
NC score	0.017906 (rank : 124)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	148	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

SMRC2_HUMAN
NC score	0.017893 (rank : 125)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	148	Target Neighborhood Hits	499	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

MDC1_HUMAN
NC score	0.016284 (rank : 126)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	148	Target Neighborhood Hits	1446	Shared Neighborhood Hits	33
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

K1914_MOUSE
NC score	0.016175 (rank : 127)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	148	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

FA44A_HUMAN
NC score	0.015667 (rank : 128)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	148	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

ATF2_HUMAN
NC score	0.015611 (rank : 129)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	148	Target Neighborhood Hits	402	Shared Neighborhood Hits	9
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ANR12_HUMAN
NC score	0.015507 (rank : 130)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	148	Target Neighborhood Hits	1081	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

MCM2_MOUSE
NC score	0.015364 (rank : 131)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	148	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P97310, O08971, O89057, Q8C2R0	Gene names	Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

ATF2_MOUSE
NC score	0.015272 (rank : 132)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	148	Target Neighborhood Hits	397	Shared Neighborhood Hits	9
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

IF5_MOUSE
NC score	0.015246 (rank : 133)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	148	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

PCLO_HUMAN
NC score	0.015108 (rank : 134)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	148	Target Neighborhood Hits	2046	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

GAK18_HUMAN
NC score	0.015102 (rank : 135)	θ value	0.163984 (rank : 72)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HPS5_HUMAN
NC score	0.014990 (rank : 136)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	148	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPZ3, O95942, Q8N4U0	Gene names	HPS5, AIBP63, KIAA1017
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein (Alpha-integrin-binding protein 63) (Ruby-eye protein 2 homolog) (Ru2).

TXD13_MOUSE
NC score	0.014305 (rank : 137)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	148	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

DAXX_HUMAN
NC score	0.014191 (rank : 138)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	148	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

KMHN1_MOUSE
NC score	0.013899 (rank : 139)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	148	Target Neighborhood Hits	949	Shared Neighborhood Hits	18
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

NCOA7_MOUSE
NC score	0.013744 (rank : 140)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q6DFV7, Q3TAR1, Q3UNB3, Q66K05, Q6ZQM4, Q8BJ15, Q8BJ39	Gene names	Ncoa7
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7.

GOGB1_HUMAN
NC score	0.012500 (rank : 141)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	148	Target Neighborhood Hits	2297	Shared Neighborhood Hits	43
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TF2AY_MOUSE
NC score	0.012213 (rank : 142)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	148	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4I4, Q99PM2, Q9DAF4	Gene names	Gtf2a1lf, Alf
Domain Architecture
Description	TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor).

SF3B1_MOUSE
NC score	0.011839 (rank : 143)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	148	Target Neighborhood Hits	352	Shared Neighborhood Hits	6
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_HUMAN
NC score	0.011829 (rank : 144)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	148	Target Neighborhood Hits	341	Shared Neighborhood Hits	6
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

RFC1_MOUSE
NC score	0.011498 (rank : 145)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	148	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

MCM2_HUMAN
NC score	0.011448 (rank : 146)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	148	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7	Gene names	MCM2, BM28, CDCL1, KIAA0030
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

ZF106_HUMAN
NC score	0.011392 (rank : 147)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	148	Target Neighborhood Hits	470	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

P55G_HUMAN
NC score	0.011149 (rank : 148)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	148	Target Neighborhood Hits	451	Shared Neighborhood Hits	12
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
NC score	0.011078 (rank : 149)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	148	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

TAXB1_MOUSE
NC score	0.010433 (rank : 150)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	148	Target Neighborhood Hits	886	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

RIR1_HUMAN
NC score	0.010397 (rank : 151)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	148	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P23921, Q9UNN2	Gene names	RRM1, RR1
Domain Architecture
Description	Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleoside-diphosphate reductase M1 subunit) (Ribonucleotide reductase large chain).

PHC1_HUMAN
NC score	0.010174 (rank : 152)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	148	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

GOGA4_HUMAN
NC score	0.009839 (rank : 153)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	148	Target Neighborhood Hits	2034	Shared Neighborhood Hits	39
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MSH6_HUMAN
NC score	0.009390 (rank : 154)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	148	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

XKR5_MOUSE
NC score	0.008257 (rank : 155)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	148	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH66	Gene names	Xkr5, Xrg5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

CING_MOUSE
NC score	0.008018 (rank : 156)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	148	Target Neighborhood Hits	1432	Shared Neighborhood Hits	25
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

BRE1A_HUMAN
NC score	0.007583 (rank : 157)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	148	Target Neighborhood Hits	1071	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

STAM1_MOUSE
NC score	0.007456 (rank : 158)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	148	Target Neighborhood Hits	273	Shared Neighborhood Hits	6
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ERGI3_HUMAN
NC score	0.007352 (rank : 159)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	148	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y282, Q6ZWP7, Q9H276, Q9P1L3	Gene names	ERGIC3, C20orf47, ERV46, SDBCAG84
Domain Architecture	No domain graphic available
Description	Endoplasmic reticulum-Golgi intermediate compartment protein 3 (Serologically defined breast cancer antigen NY-BR-84).

LZTS1_MOUSE
NC score	0.007011 (rank : 160)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	148	Target Neighborhood Hits	540	Shared Neighborhood Hits	11
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

SP100_HUMAN
NC score	0.006812 (rank : 161)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	148	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

AKAP9_HUMAN
NC score	0.006659 (rank : 162)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	148	Target Neighborhood Hits	1710	Shared Neighborhood Hits	26
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

SVIL_HUMAN
NC score	0.006554 (rank : 163)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	148	Target Neighborhood Hits	232	Shared Neighborhood Hits	11
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

PRG3_HUMAN
NC score	0.006535 (rank : 164)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	148	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

STAM1_HUMAN
NC score	0.006089 (rank : 165)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	148	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

UTRO_HUMAN
NC score	0.005324 (rank : 166)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	148	Target Neighborhood Hits	960	Shared Neighborhood Hits	21
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

SHAN2_HUMAN
NC score	0.004695 (rank : 167)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	148	Target Neighborhood Hits	346	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

RIMS2_HUMAN
NC score	0.003865 (rank : 168)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	148	Target Neighborhood Hits	342	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

KS6C1_MOUSE
NC score	0.001807 (rank : 169)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	148	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

TGFR2_MOUSE
NC score	-0.003236 (rank : 170)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	148	Target Neighborhood Hits	748	Shared Neighborhood Hits	2
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).