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Network neighborhood for query Sequence : DICER_HUMAN

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DICER_HUMAN
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DICER_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
θ value	0 (rank : 2)	NC score	0.994583 (rank : 2)
Query Neighborhood Hits	126	Target Neighborhood Hits	140	Shared Neighborhood Hits	102
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DDX58_HUMAN
θ value	4.73814e-25 (rank : 3)	NC score	0.587370 (rank : 3)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	57
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	1.80466e-16 (rank : 4)	NC score	0.564348 (rank : 8)
Query Neighborhood Hits	126	Target Neighborhood Hits	99	Shared Neighborhood Hits	60
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

IFIH1_MOUSE
θ value	3.40345e-15 (rank : 5)	NC score	0.570915 (rank : 6)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

IFIH1_HUMAN
θ value	5.8054e-15 (rank : 6)	NC score	0.577964 (rank : 5)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
θ value	9.90251e-15 (rank : 7)	NC score	0.585119 (rank : 4)
Query Neighborhood Hits	126	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

LGP2_MOUSE
θ value	3.52202e-12 (rank : 8)	NC score	0.570766 (rank : 7)
Query Neighborhood Hits	126	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

FANCM_HUMAN
θ value	1.133e-10 (rank : 9)	NC score	0.496466 (rank : 9)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

RNC_HUMAN
θ value	1.47974e-10 (rank : 10)	NC score	0.278346 (rank : 80)
Query Neighborhood Hits	126	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

FANCM_MOUSE
θ value	2.79066e-09 (rank : 11)	NC score	0.490041 (rank : 10)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DDX47_HUMAN
θ value	3.77169e-06 (rank : 12)	NC score	0.431263 (rank : 18)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	3.77169e-06 (rank : 13)	NC score	0.431169 (rank : 19)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX3X_HUMAN
θ value	6.43352e-06 (rank : 14)	NC score	0.431702 (rank : 17)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	82
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	1.09739e-05 (rank : 15)	NC score	0.430928 (rank : 20)
Query Neighborhood Hits	126	Target Neighborhood Hits	117	Shared Neighborhood Hits	82
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
θ value	1.09739e-05 (rank : 16)	NC score	0.429233 (rank : 21)
Query Neighborhood Hits	126	Target Neighborhood Hits	120	Shared Neighborhood Hits	82
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_HUMAN
θ value	2.44474e-05 (rank : 17)	NC score	0.429080 (rank : 22)
Query Neighborhood Hits	126	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

IF4A2_HUMAN
θ value	2.44474e-05 (rank : 18)	NC score	0.434806 (rank : 11)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	2.44474e-05 (rank : 19)	NC score	0.434806 (rank : 12)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A1_HUMAN
θ value	3.19293e-05 (rank : 20)	NC score	0.434629 (rank : 13)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	82
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	3.19293e-05 (rank : 21)	NC score	0.434629 (rank : 14)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	82
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX48_HUMAN
θ value	7.1131e-05 (rank : 22)	NC score	0.432519 (rank : 16)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	7.1131e-05 (rank : 23)	NC score	0.432525 (rank : 15)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX3Y_MOUSE
θ value	9.29e-05 (rank : 24)	NC score	0.427104 (rank : 24)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX27_HUMAN
θ value	0.000121331 (rank : 25)	NC score	0.425719 (rank : 25)
Query Neighborhood Hits	126	Target Neighborhood Hits	197	Shared Neighborhood Hits	84
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX4_MOUSE
θ value	0.00020696 (rank : 26)	NC score	0.427264 (rank : 23)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX27_MOUSE
θ value	0.00035302 (rank : 27)	NC score	0.421751 (rank : 27)
Query Neighborhood Hits	126	Target Neighborhood Hits	174	Shared Neighborhood Hits	83
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX4_HUMAN
θ value	0.00035302 (rank : 28)	NC score	0.424909 (rank : 26)
Query Neighborhood Hits	126	Target Neighborhood Hits	123	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX20_HUMAN
θ value	0.000786445 (rank : 29)	NC score	0.401359 (rank : 54)
Query Neighborhood Hits	126	Target Neighborhood Hits	121	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	0.00102713 (rank : 30)	NC score	0.399831 (rank : 55)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX21_HUMAN
θ value	0.00102713 (rank : 31)	NC score	0.415850 (rank : 35)
Query Neighborhood Hits	126	Target Neighborhood Hits	308	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX24_HUMAN
θ value	0.00102713 (rank : 32)	NC score	0.402072 (rank : 53)
Query Neighborhood Hits	126	Target Neighborhood Hits	190	Shared Neighborhood Hits	81
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX55_HUMAN
θ value	0.00102713 (rank : 33)	NC score	0.410851 (rank : 40)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	0.00102713 (rank : 34)	NC score	0.410446 (rank : 41)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX21_MOUSE
θ value	0.00175202 (rank : 35)	NC score	0.409855 (rank : 43)
Query Neighborhood Hits	126	Target Neighborhood Hits	350	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX41_HUMAN
θ value	0.00175202 (rank : 36)	NC score	0.416677 (rank : 33)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	0.00175202 (rank : 37)	NC score	0.416672 (rank : 34)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX50_HUMAN
θ value	0.00175202 (rank : 38)	NC score	0.419063 (rank : 30)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
θ value	0.00175202 (rank : 39)	NC score	0.417376 (rank : 32)
Query Neighborhood Hits	126	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX6_HUMAN
θ value	0.00175202 (rank : 40)	NC score	0.403710 (rank : 49)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX43_HUMAN
θ value	0.00228821 (rank : 41)	NC score	0.415368 (rank : 36)
Query Neighborhood Hits	126	Target Neighborhood Hits	120	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX46_HUMAN
θ value	0.00298849 (rank : 42)	NC score	0.411478 (rank : 39)
Query Neighborhood Hits	126	Target Neighborhood Hits	357	Shared Neighborhood Hits	88
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	0.00298849 (rank : 43)	NC score	0.410311 (rank : 42)
Query Neighborhood Hits	126	Target Neighborhood Hits	358	Shared Neighborhood Hits	87
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX51_MOUSE
θ value	0.00298849 (rank : 44)	NC score	0.418223 (rank : 31)
Query Neighborhood Hits	126	Target Neighborhood Hits	130	Shared Neighborhood Hits	84
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX52_HUMAN
θ value	0.00298849 (rank : 45)	NC score	0.419294 (rank : 29)
Query Neighborhood Hits	126	Target Neighborhood Hits	107	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
θ value	0.00298849 (rank : 46)	NC score	0.420473 (rank : 28)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX10_HUMAN
θ value	0.00509761 (rank : 47)	NC score	0.390935 (rank : 67)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX6_MOUSE
θ value	0.00509761 (rank : 48)	NC score	0.402288 (rank : 52)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX17_HUMAN
θ value	0.00665767 (rank : 49)	NC score	0.412569 (rank : 38)
Query Neighborhood Hits	126	Target Neighborhood Hits	104	Shared Neighborhood Hits	82
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	0.00665767 (rank : 50)	NC score	0.412639 (rank : 37)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	82
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX24_MOUSE
θ value	0.00665767 (rank : 51)	NC score	0.398745 (rank : 56)
Query Neighborhood Hits	126	Target Neighborhood Hits	147	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX25_HUMAN
θ value	0.00665767 (rank : 52)	NC score	0.403590 (rank : 50)
Query Neighborhood Hits	126	Target Neighborhood Hits	93	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
θ value	0.00665767 (rank : 53)	NC score	0.404982 (rank : 48)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX51_HUMAN
θ value	0.00665767 (rank : 54)	NC score	0.408953 (rank : 44)
Query Neighborhood Hits	126	Target Neighborhood Hits	332	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

PIWL1_HUMAN
θ value	0.00665767 (rank : 55)	NC score	0.098070 (rank : 91)
Query Neighborhood Hits	126	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q96J94, O95404, Q8NA60, Q8TBY5, Q96JD5	Gene names	PIWIL1, HIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

DDX10_MOUSE
θ value	0.00869519 (rank : 56)	NC score	0.389715 (rank : 69)
Query Neighborhood Hits	126	Target Neighborhood Hits	233	Shared Neighborhood Hits	76
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

PIWL1_MOUSE
θ value	0.00869519 (rank : 57)	NC score	0.097356 (rank : 92)
Query Neighborhood Hits	126	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JMB7	Gene names	Piwil1, Miwi
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

U520_HUMAN
θ value	0.0113563 (rank : 58)	NC score	0.193987 (rank : 85)
Query Neighborhood Hits	126	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

DDX23_HUMAN
θ value	0.0193708 (rank : 59)	NC score	0.397765 (rank : 58)
Query Neighborhood Hits	126	Target Neighborhood Hits	486	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

RECQ4_HUMAN
θ value	0.0252991 (rank : 60)	NC score	0.290835 (rank : 79)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	82
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

DDX39_HUMAN
θ value	0.0330416 (rank : 61)	NC score	0.397924 (rank : 57)
Query Neighborhood Hits	126	Target Neighborhood Hits	94	Shared Neighborhood Hits	81
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX39_MOUSE
θ value	0.0330416 (rank : 62)	NC score	0.396866 (rank : 59)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX5_HUMAN
θ value	0.0330416 (rank : 63)	NC score	0.405947 (rank : 46)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	0.0330416 (rank : 64)	NC score	0.405970 (rank : 45)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	82
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX18_MOUSE
θ value	0.0431538 (rank : 65)	NC score	0.393525 (rank : 61)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX49_HUMAN
θ value	0.0431538 (rank : 66)	NC score	0.405329 (rank : 47)
Query Neighborhood Hits	126	Target Neighborhood Hits	223	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DD19A_MOUSE
θ value	0.0563607 (rank : 67)	NC score	0.392542 (rank : 62)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

HELC1_HUMAN
θ value	0.0563607 (rank : 68)	NC score	0.191050 (rank : 88)
Query Neighborhood Hits	126	Target Neighborhood Hits	71	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

DD19A_HUMAN
θ value	0.0736092 (rank : 69)	NC score	0.391945 (rank : 63)
Query Neighborhood Hits	126	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
θ value	0.0736092 (rank : 70)	NC score	0.391725 (rank : 64)
Query Neighborhood Hits	126	Target Neighborhood Hits	109	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX18_HUMAN
θ value	0.0961366 (rank : 71)	NC score	0.385683 (rank : 70)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX49_MOUSE
θ value	0.0961366 (rank : 72)	NC score	0.402526 (rank : 51)
Query Neighborhood Hits	126	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

UAP56_HUMAN
θ value	0.0961366 (rank : 73)	NC score	0.391473 (rank : 65)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	80
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	0.0961366 (rank : 74)	NC score	0.391424 (rank : 66)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX28_MOUSE
θ value	0.125558 (rank : 75)	NC score	0.394412 (rank : 60)
Query Neighborhood Hits	126	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

PIWL4_MOUSE
θ value	0.163984 (rank : 76)	NC score	0.087782 (rank : 93)
Query Neighborhood Hits	126	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGT6, Q8CC75	Gene names	Piwil4, Miwi2
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4 (mAgo5).

DDX1_HUMAN
θ value	0.21417 (rank : 77)	NC score	0.373440 (rank : 76)
Query Neighborhood Hits	126	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	0.21417 (rank : 78)	NC score	0.374802 (rank : 74)
Query Neighborhood Hits	126	Target Neighborhood Hits	112	Shared Neighborhood Hits	79
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

ECM29_MOUSE
θ value	0.21417 (rank : 79)	NC score	0.056364 (rank : 98)
Query Neighborhood Hits	126	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

RECQ4_MOUSE
θ value	0.21417 (rank : 80)	NC score	0.267102 (rank : 81)
Query Neighborhood Hits	126	Target Neighborhood Hits	206	Shared Neighborhood Hits	81
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DDX28_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.382978 (rank : 71)
Query Neighborhood Hits	126	Target Neighborhood Hits	103	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

PIWL4_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.078498 (rank : 94)
Query Neighborhood Hits	126	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3Z4, Q68CZ4, Q8N8G9, Q8N9V8, Q8NEH2	Gene names	PIWIL4, HILI2, PIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4.

DDX31_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.378615 (rank : 72)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX53_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.390623 (rank : 68)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

RECQ1_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.206005 (rank : 82)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	72
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

DDX54_MOUSE
θ value	1.06291 (rank : 86)	NC score	0.377124 (rank : 73)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

PRDM2_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.004445 (rank : 126)
Query Neighborhood Hits	126	Target Neighborhood Hits	1135	Shared Neighborhood Hits	5
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SYRC_HUMAN
θ value	1.06291 (rank : 88)	NC score	0.033502 (rank : 103)
Query Neighborhood Hits	126	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P54136, Q9BWA1	Gene names	RARS
Domain Architecture
Description	Arginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.19) (Arginine--tRNA ligase) (ArgRS).

PAR14_MOUSE
θ value	1.38821 (rank : 89)	NC score	0.018097 (rank : 108)
Query Neighborhood Hits	126	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PIWL2_MOUSE
θ value	1.38821 (rank : 90)	NC score	0.071873 (rank : 95)
Query Neighborhood Hits	126	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CDG1, Q3TQE8, Q99MV6, Q9JMB6	Gene names	Piwil2, Mili
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

DDX54_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.373506 (rank : 75)
Query Neighborhood Hits	126	Target Neighborhood Hits	170	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

K1914_MOUSE
θ value	1.81305 (rank : 92)	NC score	0.038436 (rank : 101)
Query Neighborhood Hits	126	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

PIWL2_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.069867 (rank : 96)
Query Neighborhood Hits	126	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TC59, Q96SW6, Q9NW28	Gene names	PIWIL2, HILI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

TBL2_MOUSE
θ value	1.81305 (rank : 94)	NC score	0.035437 (rank : 102)
Query Neighborhood Hits	126	Target Neighborhood Hits	221	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R099	Gene names	Tbl2
Domain Architecture
Description	Transducin beta-like 2 protein.

ENW1_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.028942 (rank : 104)
Query Neighborhood Hits	126	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

IGS4B_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.013750 (rank : 112)
Query Neighborhood Hits	126	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

ADA19_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.008400 (rank : 121)
Query Neighborhood Hits	126	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ANR11_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.005929 (rank : 124)
Query Neighborhood Hits	126	Target Neighborhood Hits	1289	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

IGS4B_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.013142 (rank : 113)
Query Neighborhood Hits	126	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

LRC34_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.023630 (rank : 106)
Query Neighborhood Hits	126	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

MAP1A_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.009840 (rank : 118)
Query Neighborhood Hits	126	Target Neighborhood Hits	1626	Shared Neighborhood Hits	12
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

HERC2_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.015415 (rank : 109)
Query Neighborhood Hits	126	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

LRC34_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.020733 (rank : 107)
Query Neighborhood Hits	126	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

M3K5_HUMAN
θ value	4.03905 (rank : 104)	NC score	-0.002685 (rank : 132)
Query Neighborhood Hits	126	Target Neighborhood Hits	868	Shared Neighborhood Hits	5
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

SPAG5_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.006614 (rank : 123)
Query Neighborhood Hits	126	Target Neighborhood Hits	612	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SYRC_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.027439 (rank : 105)
Query Neighborhood Hits	126	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0I9, Q8VDW1	Gene names	Rars
Domain Architecture
Description	Arginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.19) (Arginine--tRNA ligase) (ArgRS).

HERC2_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.015036 (rank : 110)
Query Neighborhood Hits	126	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

K1333_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.011705 (rank : 114)
Query Neighborhood Hits	126	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1914_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.039735 (rank : 100)
Query Neighborhood Hits	126	Target Neighborhood Hits	255	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

MRC2_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.011570 (rank : 115)
Query Neighborhood Hits	126	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

RECQ1_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.193868 (rank : 86)
Query Neighborhood Hits	126	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

TITIN_HUMAN
θ value	5.27518 (rank : 112)	NC score	-0.003088 (rank : 133)
Query Neighborhood Hits	126	Target Neighborhood Hits	2923	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

FANCB_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.014831 (rank : 111)
Query Neighborhood Hits	126	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q5XJY6	Gene names	Fancb
Domain Architecture	No domain graphic available
Description	Fanconi anemia group B protein homolog (Protein FACB).

GOGA4_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.005027 (rank : 125)
Query Neighborhood Hits	126	Target Neighborhood Hits	2034	Shared Neighborhood Hits	23
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

LAMA2_HUMAN
θ value	6.88961 (rank : 115)	NC score	-0.000500 (rank : 129)
Query Neighborhood Hits	126	Target Neighborhood Hits	1092	Shared Neighborhood Hits	5
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MAML3_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.009356 (rank : 120)
Query Neighborhood Hits	126	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

I12R1_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.010795 (rank : 117)
Query Neighborhood Hits	126	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

MPP4_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.003477 (rank : 127)
Query Neighborhood Hits	126	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MRC2_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.009361 (rank : 119)
Query Neighborhood Hits	126	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

PKHD1_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.011564 (rank : 116)
Query Neighborhood Hits	126	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TCZ9	Gene names	PKHD1, FCYT, TIGM1
Domain Architecture
Description	Polycystic kidney and hepatic disease 1 precursor (Fibrocystin) (Polyductin) (Tigmin).

TMPS6_MOUSE
θ value	8.99809 (rank : 121)	NC score	-0.000895 (rank : 130)
Query Neighborhood Hits	126	Target Neighborhood Hits	341	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TTLL5_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.006713 (rank : 122)
Query Neighborhood Hits	126	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

VRK2_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.002128 (rank : 128)
Query Neighborhood Hits	126	Target Neighborhood Hits	582	Shared Neighborhood Hits	4
SwissProt Accessions	Q86Y07, Q49AK9, Q53EU9, Q86Y08, Q86Y09, Q86Y10, Q86Y11, Q86Y12, Q8IXI5, Q99987	Gene names	VRK2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

WRN_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.199851 (rank : 83)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	77
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

WRN_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.187281 (rank : 90)
Query Neighborhood Hits	126	Target Neighborhood Hits	295	Shared Neighborhood Hits	74
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

ZBTB1_MOUSE
θ value	8.99809 (rank : 126)	NC score	-0.001417 (rank : 131)
Query Neighborhood Hits	126	Target Neighborhood Hits	795	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VL9, Q8CDP7, Q99LD2	Gene names	Zbtb1
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.

BLM_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.189548 (rank : 89)
Query Neighborhood Hits	126	Target Neighborhood Hits	148	Shared Neighborhood Hits	73
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.194639 (rank : 84)
Query Neighborhood Hits	126	Target Neighborhood Hits	108	Shared Neighborhood Hits	68
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

CC026_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.064058 (rank : 97)
Query Neighborhood Hits	126	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX56_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.353553 (rank : 78)
Query Neighborhood Hits	126	Target Neighborhood Hits	77	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.353709 (rank : 77)
Query Neighborhood Hits	126	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

PIWL3_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.054441 (rank : 99)
Query Neighborhood Hits	126	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z3Z3	Gene names	PIWIL3
Domain Architecture	No domain graphic available
Description	Piwi-like protein 3.

RECQ5_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.191471 (rank : 87)
Query Neighborhood Hits	126	Target Neighborhood Hits	390	Shared Neighborhood Hits	75
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

Hits sorted by NC score

DICER_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.994583 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	126	Target Neighborhood Hits	140	Shared Neighborhood Hits	102
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DDX58_HUMAN
NC score	0.587370 (rank : 3)	θ value	4.73814e-25 (rank : 3)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	57
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

LGP2_HUMAN
NC score	0.585119 (rank : 4)	θ value	9.90251e-15 (rank : 7)
Query Neighborhood Hits	126	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_HUMAN
NC score	0.577964 (rank : 5)	θ value	5.8054e-15 (rank : 6)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
NC score	0.570915 (rank : 6)	θ value	3.40345e-15 (rank : 5)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LGP2_MOUSE
NC score	0.570766 (rank : 7)	θ value	3.52202e-12 (rank : 8)
Query Neighborhood Hits	126	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

DDX58_MOUSE
NC score	0.564348 (rank : 8)	θ value	1.80466e-16 (rank : 4)
Query Neighborhood Hits	126	Target Neighborhood Hits	99	Shared Neighborhood Hits	60
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

FANCM_HUMAN
NC score	0.496466 (rank : 9)	θ value	1.133e-10 (rank : 9)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.490041 (rank : 10)	θ value	2.79066e-09 (rank : 11)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

IF4A2_HUMAN
NC score	0.434806 (rank : 11)	θ value	2.44474e-05 (rank : 18)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.434806 (rank : 12)	θ value	2.44474e-05 (rank : 19)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A1_HUMAN
NC score	0.434629 (rank : 13)	θ value	3.19293e-05 (rank : 20)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	82
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.434629 (rank : 14)	θ value	3.19293e-05 (rank : 21)
Query Neighborhood Hits	126	Target Neighborhood Hits	106	Shared Neighborhood Hits	82
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX48_MOUSE
NC score	0.432525 (rank : 15)	θ value	7.1131e-05 (rank : 23)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX48_HUMAN
NC score	0.432519 (rank : 16)	θ value	7.1131e-05 (rank : 22)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX3X_HUMAN
NC score	0.431702 (rank : 17)	θ value	6.43352e-06 (rank : 14)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	82
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX47_HUMAN
NC score	0.431263 (rank : 18)	θ value	3.77169e-06 (rank : 12)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
NC score	0.431169 (rank : 19)	θ value	3.77169e-06 (rank : 13)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX3X_MOUSE
NC score	0.430928 (rank : 20)	θ value	1.09739e-05 (rank : 15)
Query Neighborhood Hits	126	Target Neighborhood Hits	117	Shared Neighborhood Hits	82
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
NC score	0.429233 (rank : 21)	θ value	1.09739e-05 (rank : 16)
Query Neighborhood Hits	126	Target Neighborhood Hits	120	Shared Neighborhood Hits	82
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3Y_HUMAN
NC score	0.429080 (rank : 22)	θ value	2.44474e-05 (rank : 17)
Query Neighborhood Hits	126	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX4_MOUSE
NC score	0.427264 (rank : 23)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX3Y_MOUSE
NC score	0.427104 (rank : 24)	θ value	9.29e-05 (rank : 24)
Query Neighborhood Hits	126	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX27_HUMAN
NC score	0.425719 (rank : 25)	θ value	0.000121331 (rank : 25)
Query Neighborhood Hits	126	Target Neighborhood Hits	197	Shared Neighborhood Hits	84
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX4_HUMAN
NC score	0.424909 (rank : 26)	θ value	0.00035302 (rank : 28)
Query Neighborhood Hits	126	Target Neighborhood Hits	123	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX27_MOUSE
NC score	0.421751 (rank : 27)	θ value	0.00035302 (rank : 27)
Query Neighborhood Hits	126	Target Neighborhood Hits	174	Shared Neighborhood Hits	83
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX52_MOUSE
NC score	0.420473 (rank : 28)	θ value	0.00298849 (rank : 46)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_HUMAN
NC score	0.419294 (rank : 29)	θ value	0.00298849 (rank : 45)
Query Neighborhood Hits	126	Target Neighborhood Hits	107	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX50_HUMAN
NC score	0.419063 (rank : 30)	θ value	0.00175202 (rank : 38)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX51_MOUSE
NC score	0.418223 (rank : 31)	θ value	0.00298849 (rank : 44)
Query Neighborhood Hits	126	Target Neighborhood Hits	130	Shared Neighborhood Hits	84
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX50_MOUSE
NC score	0.417376 (rank : 32)	θ value	0.00175202 (rank : 39)
Query Neighborhood Hits	126	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX41_HUMAN
NC score	0.416677 (rank : 33)	θ value	0.00175202 (rank : 36)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.416672 (rank : 34)	θ value	0.00175202 (rank : 37)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX21_HUMAN
NC score	0.415850 (rank : 35)	θ value	0.00102713 (rank : 31)
Query Neighborhood Hits	126	Target Neighborhood Hits	308	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX43_HUMAN
NC score	0.415368 (rank : 36)	θ value	0.00228821 (rank : 41)
Query Neighborhood Hits	126	Target Neighborhood Hits	120	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX17_MOUSE
NC score	0.412639 (rank : 37)	θ value	0.00665767 (rank : 50)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	82
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.412569 (rank : 38)	θ value	0.00665767 (rank : 49)
Query Neighborhood Hits	126	Target Neighborhood Hits	104	Shared Neighborhood Hits	82
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX46_HUMAN
NC score	0.411478 (rank : 39)	θ value	0.00298849 (rank : 42)
Query Neighborhood Hits	126	Target Neighborhood Hits	357	Shared Neighborhood Hits	88
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX55_HUMAN
NC score	0.410851 (rank : 40)	θ value	0.00102713 (rank : 33)
Query Neighborhood Hits	126	Target Neighborhood Hits	122	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
NC score	0.410446 (rank : 41)	θ value	0.00102713 (rank : 34)
Query Neighborhood Hits	126	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX46_MOUSE
NC score	0.410311 (rank : 42)	θ value	0.00298849 (rank : 43)
Query Neighborhood Hits	126	Target Neighborhood Hits	358	Shared Neighborhood Hits	87
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX21_MOUSE
NC score	0.409855 (rank : 43)	θ value	0.00175202 (rank : 35)
Query Neighborhood Hits	126	Target Neighborhood Hits	350	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX51_HUMAN
NC score	0.408953 (rank : 44)	θ value	0.00665767 (rank : 54)
Query Neighborhood Hits	126	Target Neighborhood Hits	332	Shared Neighborhood Hits	84
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX5_MOUSE
NC score	0.405970 (rank : 45)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	126	Target Neighborhood Hits	101	Shared Neighborhood Hits	82
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.405947 (rank : 46)	θ value	0.0330416 (rank : 63)
Query Neighborhood Hits	126	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX49_HUMAN
NC score	0.405329 (rank : 47)	θ value	0.0431538 (rank : 66)
Query Neighborhood Hits	126	Target Neighborhood Hits	223	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX25_MOUSE
NC score	0.404982 (rank : 48)	θ value	0.00665767 (rank : 53)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX6_HUMAN
NC score	0.403710 (rank : 49)	θ value	0.00175202 (rank : 40)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	82
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX25_HUMAN
NC score	0.403590 (rank : 50)	θ value	0.00665767 (rank : 52)
Query Neighborhood Hits	126	Target Neighborhood Hits	93	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX49_MOUSE
NC score	0.402526 (rank : 51)	θ value	0.0961366 (rank : 72)
Query Neighborhood Hits	126	Target Neighborhood Hits	119	Shared Neighborhood Hits	84
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX6_MOUSE
NC score	0.402288 (rank : 52)	θ value	0.00509761 (rank : 48)
Query Neighborhood Hits	126	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX24_HUMAN
NC score	0.402072 (rank : 53)	θ value	0.00102713 (rank : 32)
Query Neighborhood Hits	126	Target Neighborhood Hits	190	Shared Neighborhood Hits	81
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX20_HUMAN
NC score	0.401359 (rank : 54)	θ value	0.000786445 (rank : 29)
Query Neighborhood Hits	126	Target Neighborhood Hits	121	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
NC score	0.399831 (rank : 55)	θ value	0.00102713 (rank : 30)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX24_MOUSE
NC score	0.398745 (rank : 56)	θ value	0.00665767 (rank : 51)
Query Neighborhood Hits	126	Target Neighborhood Hits	147	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX39_HUMAN
NC score	0.397924 (rank : 57)	θ value	0.0330416 (rank : 61)
Query Neighborhood Hits	126	Target Neighborhood Hits	94	Shared Neighborhood Hits	81
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX23_HUMAN
NC score	0.397765 (rank : 58)	θ value	0.0193708 (rank : 59)
Query Neighborhood Hits	126	Target Neighborhood Hits	486	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX39_MOUSE
NC score	0.396866 (rank : 59)	θ value	0.0330416 (rank : 62)
Query Neighborhood Hits	126	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX28_MOUSE
NC score	0.394412 (rank : 60)	θ value	0.125558 (rank : 75)
Query Neighborhood Hits	126	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX18_MOUSE
NC score	0.393525 (rank : 61)	θ value	0.0431538 (rank : 65)
Query Neighborhood Hits	126	Target Neighborhood Hits	115	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DD19A_MOUSE
NC score	0.392542 (rank : 62)	θ value	0.0563607 (rank : 67)
Query Neighborhood Hits	126	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19A_HUMAN
NC score	0.391945 (rank : 63)	θ value	0.0736092 (rank : 69)
Query Neighborhood Hits	126	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.391725 (rank : 64)	θ value	0.0736092 (rank : 70)
Query Neighborhood Hits	126	Target Neighborhood Hits	109	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

UAP56_HUMAN
NC score	0.391473 (rank : 65)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	80
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.391424 (rank : 66)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	126	Target Neighborhood Hits	96	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX10_HUMAN
NC score	0.390935 (rank : 67)	θ value	0.00509761 (rank : 47)
Query Neighborhood Hits	126	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX53_HUMAN
NC score	0.390623 (rank : 68)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX10_MOUSE
NC score	0.389715 (rank : 69)	θ value	0.00869519 (rank : 56)
Query Neighborhood Hits	126	Target Neighborhood Hits	233	Shared Neighborhood Hits	76
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_HUMAN
NC score	0.385683 (rank : 70)	θ value	0.0961366 (rank : 71)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX28_HUMAN
NC score	0.382978 (rank : 71)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	126	Target Neighborhood Hits	103	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX31_HUMAN
NC score	0.378615 (rank : 72)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX54_MOUSE
NC score	0.377124 (rank : 73)	θ value	1.06291 (rank : 86)
Query Neighborhood Hits	126	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX1_MOUSE
NC score	0.374802 (rank : 74)	θ value	0.21417 (rank : 78)
Query Neighborhood Hits	126	Target Neighborhood Hits	112	Shared Neighborhood Hits	79
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX54_HUMAN
NC score	0.373506 (rank : 75)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	126	Target Neighborhood Hits	170	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX1_HUMAN
NC score	0.373440 (rank : 76)	θ value	0.21417 (rank : 77)
Query Neighborhood Hits	126	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX56_MOUSE
NC score	0.353709 (rank : 77)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	126	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
NC score	0.353553 (rank : 78)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	126	Target Neighborhood Hits	77	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

RECQ4_HUMAN
NC score	0.290835 (rank : 79)	θ value	0.0252991 (rank : 60)
Query Neighborhood Hits	126	Target Neighborhood Hits	177	Shared Neighborhood Hits	82
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RNC_HUMAN
NC score	0.278346 (rank : 80)	θ value	1.47974e-10 (rank : 10)
Query Neighborhood Hits	126	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

RECQ4_MOUSE
NC score	0.267102 (rank : 81)	θ value	0.21417 (rank : 80)
Query Neighborhood Hits	126	Target Neighborhood Hits	206	Shared Neighborhood Hits	81
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ1_HUMAN
NC score	0.206005 (rank : 82)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	126	Target Neighborhood Hits	100	Shared Neighborhood Hits	72
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_HUMAN
NC score	0.199851 (rank : 83)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	126	Target Neighborhood Hits	132	Shared Neighborhood Hits	77
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

BLM_MOUSE
NC score	0.194639 (rank : 84)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	126	Target Neighborhood Hits	108	Shared Neighborhood Hits	68
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

U520_HUMAN
NC score	0.193987 (rank : 85)	θ value	0.0113563 (rank : 58)
Query Neighborhood Hits	126	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

RECQ1_MOUSE
NC score	0.193868 (rank : 86)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	126	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ5_HUMAN
NC score	0.191471 (rank : 87)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	126	Target Neighborhood Hits	390	Shared Neighborhood Hits	75
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

HELC1_HUMAN
NC score	0.191050 (rank : 88)	θ value	0.0563607 (rank : 68)
Query Neighborhood Hits	126	Target Neighborhood Hits	71	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

BLM_HUMAN
NC score	0.189548 (rank : 89)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	126	Target Neighborhood Hits	148	Shared Neighborhood Hits	73
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_MOUSE
NC score	0.187281 (rank : 90)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	126	Target Neighborhood Hits	295	Shared Neighborhood Hits	74
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

PIWL1_HUMAN
NC score	0.098070 (rank : 91)	θ value	0.00665767 (rank : 55)
Query Neighborhood Hits	126	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q96J94, O95404, Q8NA60, Q8TBY5, Q96JD5	Gene names	PIWIL1, HIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PIWL1_MOUSE
NC score	0.097356 (rank : 92)	θ value	0.00869519 (rank : 57)
Query Neighborhood Hits	126	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JMB7	Gene names	Piwil1, Miwi
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PIWL4_MOUSE
NC score	0.087782 (rank : 93)	θ value	0.163984 (rank : 76)
Query Neighborhood Hits	126	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGT6, Q8CC75	Gene names	Piwil4, Miwi2
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4 (mAgo5).

PIWL4_HUMAN
NC score	0.078498 (rank : 94)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	126	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z3Z4, Q68CZ4, Q8N8G9, Q8N9V8, Q8NEH2	Gene names	PIWIL4, HILI2, PIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 4.

PIWL2_MOUSE
NC score	0.071873 (rank : 95)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	126	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CDG1, Q3TQE8, Q99MV6, Q9JMB6	Gene names	Piwil2, Mili
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

PIWL2_HUMAN
NC score	0.069867 (rank : 96)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	126	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TC59, Q96SW6, Q9NW28	Gene names	PIWIL2, HILI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

CC026_HUMAN
NC score	0.064058 (rank : 97)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	126	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

ECM29_MOUSE
NC score	0.056364 (rank : 98)	θ value	0.21417 (rank : 79)
Query Neighborhood Hits	126	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

PIWL3_HUMAN
NC score	0.054441 (rank : 99)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	126	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z3Z3	Gene names	PIWIL3
Domain Architecture	No domain graphic available
Description	Piwi-like protein 3.

K1914_HUMAN
NC score	0.039735 (rank : 100)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	126	Target Neighborhood Hits	255	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

K1914_MOUSE
NC score	0.038436 (rank : 101)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	126	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DTU0, Q8BID1, Q8K2G0	Gene names	Kiaa1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

TBL2_MOUSE
NC score	0.035437 (rank : 102)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	126	Target Neighborhood Hits	221	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R099	Gene names	Tbl2
Domain Architecture
Description	Transducin beta-like 2 protein.

SYRC_HUMAN
NC score	0.033502 (rank : 103)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	126	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P54136, Q9BWA1	Gene names	RARS
Domain Architecture
Description	Arginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.19) (Arginine--tRNA ligase) (ArgRS).

ENW1_HUMAN
NC score	0.028942 (rank : 104)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	126	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

SYRC_MOUSE
NC score	0.027439 (rank : 105)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	126	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0I9, Q8VDW1	Gene names	Rars
Domain Architecture
Description	Arginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.19) (Arginine--tRNA ligase) (ArgRS).

LRC34_MOUSE
NC score	0.023630 (rank : 106)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	126	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_HUMAN
NC score	0.020733 (rank : 107)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	126	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

PAR14_MOUSE
NC score	0.018097 (rank : 108)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	126	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

HERC2_MOUSE
NC score	0.015415 (rank : 109)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	126	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HERC2_HUMAN
NC score	0.015036 (rank : 110)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	126	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

FANCB_MOUSE
NC score	0.014831 (rank : 111)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	126	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q5XJY6	Gene names	Fancb
Domain Architecture	No domain graphic available
Description	Fanconi anemia group B protein homolog (Protein FACB).

IGS4B_MOUSE
NC score	0.013750 (rank : 112)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	126	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IGS4B_HUMAN
NC score	0.013142 (rank : 113)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	126	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

K1333_MOUSE
NC score	0.011705 (rank : 114)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	126	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

MRC2_HUMAN
NC score	0.011570 (rank : 115)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	126	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

PKHD1_HUMAN
NC score	0.011564 (rank : 116)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	126	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TCZ9	Gene names	PKHD1, FCYT, TIGM1
Domain Architecture
Description	Polycystic kidney and hepatic disease 1 precursor (Fibrocystin) (Polyductin) (Tigmin).

I12R1_MOUSE
NC score	0.010795 (rank : 117)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	126	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

MAP1A_HUMAN
NC score	0.009840 (rank : 118)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	126	Target Neighborhood Hits	1626	Shared Neighborhood Hits	12
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MRC2_MOUSE
NC score	0.009361 (rank : 119)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	126	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

MAML3_HUMAN
NC score	0.009356 (rank : 120)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	126	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

ADA19_HUMAN
NC score	0.008400 (rank : 121)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	126	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

TTLL5_MOUSE
NC score	0.006713 (rank : 122)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	126	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

SPAG5_MOUSE
NC score	0.006614 (rank : 123)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	126	Target Neighborhood Hits	612	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

ANR11_HUMAN
NC score	0.005929 (rank : 124)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	126	Target Neighborhood Hits	1289	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

GOGA4_HUMAN
NC score	0.005027 (rank : 125)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	126	Target Neighborhood Hits	2034	Shared Neighborhood Hits	23
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

PRDM2_HUMAN
NC score	0.004445 (rank : 126)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	126	Target Neighborhood Hits	1135	Shared Neighborhood Hits	5
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

MPP4_HUMAN
NC score	0.003477 (rank : 127)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	126	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

VRK2_HUMAN
NC score	0.002128 (rank : 128)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	126	Target Neighborhood Hits	582	Shared Neighborhood Hits	4
SwissProt Accessions	Q86Y07, Q49AK9, Q53EU9, Q86Y08, Q86Y09, Q86Y10, Q86Y11, Q86Y12, Q8IXI5, Q99987	Gene names	VRK2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

LAMA2_HUMAN
NC score	-0.000500 (rank : 129)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	126	Target Neighborhood Hits	1092	Shared Neighborhood Hits	5
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

TMPS6_MOUSE
NC score	-0.000895 (rank : 130)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	126	Target Neighborhood Hits	341	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ZBTB1_MOUSE
NC score	-0.001417 (rank : 131)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	126	Target Neighborhood Hits	795	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VL9, Q8CDP7, Q99LD2	Gene names	Zbtb1
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.

M3K5_HUMAN
NC score	-0.002685 (rank : 132)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	126	Target Neighborhood Hits	868	Shared Neighborhood Hits	5
SwissProt Accessions	Q99683, Q5THN3, Q99461	Gene names	MAP3K5, ASK1, MAPKKK5, MEKK5
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal- regulating kinase 1) (ASK-1).

TITIN_HUMAN
NC score	-0.003088 (rank : 133)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	126	Target Neighborhood Hits	2923	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).