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Network neighborhood for query Sequence : DDX24_MOUSE

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DDX24_MOUSE
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX24_HUMAN
θ value	0 (rank : 1)	NC score	0.992652 (rank : 2)
Query Neighborhood Hits	147	Target Neighborhood Hits	190	Shared Neighborhood Hits	97
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	147	Target Neighborhood Hits	147	Shared Neighborhood Hits	147
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX47_HUMAN
θ value	2.18568e-46 (rank : 3)	NC score	0.952062 (rank : 4)
Query Neighborhood Hits	147	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	4.86918e-46 (rank : 4)	NC score	0.952323 (rank : 3)
Query Neighborhood Hits	147	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
θ value	2.58786e-39 (rank : 5)	NC score	0.945779 (rank : 6)
Query Neighborhood Hits	147	Target Neighborhood Hits	223	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_MOUSE
θ value	1.85459e-37 (rank : 6)	NC score	0.948169 (rank : 5)
Query Neighborhood Hits	147	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX27_MOUSE
θ value	1.24399e-33 (rank : 7)	NC score	0.937487 (rank : 7)
Query Neighborhood Hits	147	Target Neighborhood Hits	174	Shared Neighborhood Hits	91
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX18_MOUSE
θ value	1.6247e-33 (rank : 8)	NC score	0.936119 (rank : 8)
Query Neighborhood Hits	147	Target Neighborhood Hits	115	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX18_HUMAN
θ value	2.77131e-33 (rank : 9)	NC score	0.936024 (rank : 9)
Query Neighborhood Hits	147	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX27_HUMAN
θ value	8.06329e-33 (rank : 10)	NC score	0.935638 (rank : 11)
Query Neighborhood Hits	147	Target Neighborhood Hits	197	Shared Neighborhood Hits	92
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX54_MOUSE
θ value	5.22648e-32 (rank : 11)	NC score	0.934685 (rank : 12)
Query Neighborhood Hits	147	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX41_HUMAN
θ value	1.52067e-31 (rank : 12)	NC score	0.934438 (rank : 14)
Query Neighborhood Hits	147	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	1.52067e-31 (rank : 13)	NC score	0.934093 (rank : 15)
Query Neighborhood Hits	147	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX17_HUMAN
θ value	2.59387e-31 (rank : 14)	NC score	0.927107 (rank : 25)
Query Neighborhood Hits	147	Target Neighborhood Hits	104	Shared Neighborhood Hits	85
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	2.59387e-31 (rank : 15)	NC score	0.927242 (rank : 24)
Query Neighborhood Hits	147	Target Neighborhood Hits	105	Shared Neighborhood Hits	85
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX55_HUMAN
θ value	9.8567e-31 (rank : 16)	NC score	0.934467 (rank : 13)
Query Neighborhood Hits	147	Target Neighborhood Hits	122	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	1.28732e-30 (rank : 17)	NC score	0.935995 (rank : 10)
Query Neighborhood Hits	147	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX10_HUMAN
θ value	1.6813e-30 (rank : 18)	NC score	0.928125 (rank : 20)
Query Neighborhood Hits	147	Target Neighborhood Hits	210	Shared Neighborhood Hits	89
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX54_HUMAN
θ value	3.74554e-30 (rank : 19)	NC score	0.930346 (rank : 18)
Query Neighborhood Hits	147	Target Neighborhood Hits	170	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX10_MOUSE
θ value	6.38894e-30 (rank : 20)	NC score	0.927443 (rank : 23)
Query Neighborhood Hits	147	Target Neighborhood Hits	233	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX48_HUMAN
θ value	2.05525e-28 (rank : 21)	NC score	0.922081 (rank : 27)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	2.05525e-28 (rank : 22)	NC score	0.921934 (rank : 28)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX46_HUMAN
θ value	4.57862e-28 (rank : 23)	NC score	0.909471 (rank : 53)
Query Neighborhood Hits	147	Target Neighborhood Hits	357	Shared Neighborhood Hits	97
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	4.57862e-28 (rank : 24)	NC score	0.907059 (rank : 55)
Query Neighborhood Hits	147	Target Neighborhood Hits	358	Shared Neighborhood Hits	96
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX31_HUMAN
θ value	5.97985e-28 (rank : 25)	NC score	0.932797 (rank : 16)
Query Neighborhood Hits	147	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX23_HUMAN
θ value	2.27234e-27 (rank : 26)	NC score	0.903142 (rank : 57)
Query Neighborhood Hits	147	Target Neighborhood Hits	486	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX43_HUMAN
θ value	3.87602e-27 (rank : 27)	NC score	0.926568 (rank : 26)
Query Neighborhood Hits	147	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX5_HUMAN
θ value	1.12775e-26 (rank : 28)	NC score	0.920380 (rank : 30)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	1.12775e-26 (rank : 29)	NC score	0.920360 (rank : 31)
Query Neighborhood Hits	147	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX6_MOUSE
θ value	4.28545e-26 (rank : 30)	NC score	0.927720 (rank : 21)
Query Neighborhood Hits	147	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX6_HUMAN
θ value	2.12685e-25 (rank : 31)	NC score	0.927686 (rank : 22)
Query Neighborhood Hits	147	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX3Y_MOUSE
θ value	2.77775e-25 (rank : 32)	NC score	0.912039 (rank : 49)
Query Neighborhood Hits	147	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX3X_HUMAN
θ value	4.73814e-25 (rank : 33)	NC score	0.911035 (rank : 50)
Query Neighborhood Hits	147	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX28_HUMAN
θ value	6.18819e-25 (rank : 34)	NC score	0.928588 (rank : 19)
Query Neighborhood Hits	147	Target Neighborhood Hits	103	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX28_MOUSE
θ value	8.08199e-25 (rank : 35)	NC score	0.930556 (rank : 17)
Query Neighborhood Hits	147	Target Neighborhood Hits	112	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX3X_MOUSE
θ value	1.05554e-24 (rank : 36)	NC score	0.910337 (rank : 52)
Query Neighborhood Hits	147	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

PL10_MOUSE
θ value	1.05554e-24 (rank : 37)	NC score	0.911011 (rank : 51)
Query Neighborhood Hits	147	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX39_MOUSE
θ value	1.37858e-24 (rank : 38)	NC score	0.918607 (rank : 36)
Query Neighborhood Hits	147	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

IF4A1_HUMAN
θ value	1.37858e-24 (rank : 39)	NC score	0.916170 (rank : 41)
Query Neighborhood Hits	147	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	1.37858e-24 (rank : 40)	NC score	0.916170 (rank : 42)
Query Neighborhood Hits	147	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	1.37858e-24 (rank : 41)	NC score	0.915884 (rank : 43)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	1.37858e-24 (rank : 42)	NC score	0.915884 (rank : 44)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX39_HUMAN
θ value	2.35151e-24 (rank : 43)	NC score	0.919058 (rank : 34)
Query Neighborhood Hits	147	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX3Y_HUMAN
θ value	2.35151e-24 (rank : 44)	NC score	0.908534 (rank : 54)
Query Neighborhood Hits	147	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

UAP56_HUMAN
θ value	2.35151e-24 (rank : 45)	NC score	0.917561 (rank : 38)
Query Neighborhood Hits	147	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	2.35151e-24 (rank : 46)	NC score	0.917501 (rank : 39)
Query Neighborhood Hits	147	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX4_HUMAN
θ value	1.5242e-23 (rank : 47)	NC score	0.918476 (rank : 37)
Query Neighborhood Hits	147	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX50_MOUSE
θ value	1.5242e-23 (rank : 48)	NC score	0.912741 (rank : 47)
Query Neighborhood Hits	147	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
θ value	1.99067e-23 (rank : 49)	NC score	0.912550 (rank : 48)
Query Neighborhood Hits	147	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX53_HUMAN
θ value	4.43474e-23 (rank : 50)	NC score	0.918840 (rank : 35)
Query Neighborhood Hits	147	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX4_MOUSE
θ value	7.56453e-23 (rank : 51)	NC score	0.919171 (rank : 33)
Query Neighborhood Hits	147	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX51_MOUSE
θ value	1.6852e-22 (rank : 52)	NC score	0.916260 (rank : 40)
Query Neighborhood Hits	147	Target Neighborhood Hits	130	Shared Neighborhood Hits	87
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX21_HUMAN
θ value	2.87452e-22 (rank : 53)	NC score	0.901293 (rank : 58)
Query Neighborhood Hits	147	Target Neighborhood Hits	308	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX51_HUMAN
θ value	1.86321e-21 (rank : 54)	NC score	0.899593 (rank : 60)
Query Neighborhood Hits	147	Target Neighborhood Hits	332	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX21_MOUSE
θ value	4.15078e-21 (rank : 55)	NC score	0.893280 (rank : 61)
Query Neighborhood Hits	147	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX1_MOUSE
θ value	1.2077e-20 (rank : 56)	NC score	0.871651 (rank : 67)
Query Neighborhood Hits	147	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX56_HUMAN
θ value	1.2077e-20 (rank : 57)	NC score	0.920853 (rank : 29)
Query Neighborhood Hits	147	Target Neighborhood Hits	77	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX20_HUMAN
θ value	5.99374e-20 (rank : 58)	NC score	0.903482 (rank : 56)
Query Neighborhood Hits	147	Target Neighborhood Hits	121	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX1_HUMAN
θ value	7.82807e-20 (rank : 59)	NC score	0.870095 (rank : 68)
Query Neighborhood Hits	147	Target Neighborhood Hits	110	Shared Neighborhood Hits	84
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX56_MOUSE
θ value	1.02238e-19 (rank : 60)	NC score	0.919756 (rank : 32)
Query Neighborhood Hits	147	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX20_MOUSE
θ value	1.33526e-19 (rank : 61)	NC score	0.900362 (rank : 59)
Query Neighborhood Hits	147	Target Neighborhood Hits	177	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX52_HUMAN
θ value	1.47631e-18 (rank : 62)	NC score	0.915585 (rank : 45)
Query Neighborhood Hits	147	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DD19A_HUMAN
θ value	1.24977e-17 (rank : 63)	NC score	0.886691 (rank : 62)
Query Neighborhood Hits	147	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
θ value	3.63628e-17 (rank : 64)	NC score	0.885516 (rank : 63)
Query Neighborhood Hits	147	Target Neighborhood Hits	109	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX52_MOUSE
θ value	6.20254e-17 (rank : 65)	NC score	0.914913 (rank : 46)
Query Neighborhood Hits	147	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DD19A_MOUSE
θ value	1.80466e-16 (rank : 66)	NC score	0.884956 (rank : 64)
Query Neighborhood Hits	147	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_MOUSE
θ value	3.76295e-14 (rank : 67)	NC score	0.882586 (rank : 66)
Query Neighborhood Hits	147	Target Neighborhood Hits	98	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_HUMAN
θ value	1.09485e-13 (rank : 68)	NC score	0.883068 (rank : 65)
Query Neighborhood Hits	147	Target Neighborhood Hits	93	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

WRN_HUMAN
θ value	2.44474e-05 (rank : 69)	NC score	0.470188 (rank : 73)
Query Neighborhood Hits	147	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ1_MOUSE
θ value	9.29e-05 (rank : 70)	NC score	0.436128 (rank : 74)
Query Neighborhood Hits	147	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_MOUSE
θ value	0.00134147 (rank : 71)	NC score	0.431007 (rank : 77)
Query Neighborhood Hits	147	Target Neighborhood Hits	295	Shared Neighborhood Hits	84
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

BLM_HUMAN
θ value	0.00390308 (rank : 72)	NC score	0.476170 (rank : 72)
Query Neighborhood Hits	147	Target Neighborhood Hits	148	Shared Neighborhood Hits	77
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	0.00665767 (rank : 73)	NC score	0.487285 (rank : 71)
Query Neighborhood Hits	147	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

DICER_HUMAN
θ value	0.00665767 (rank : 74)	NC score	0.398745 (rank : 80)
Query Neighborhood Hits	147	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
θ value	0.00665767 (rank : 75)	NC score	0.397817 (rank : 81)
Query Neighborhood Hits	147	Target Neighborhood Hits	140	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

RECQ1_HUMAN
θ value	0.00869519 (rank : 76)	NC score	0.431140 (rank : 75)
Query Neighborhood Hits	147	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ4_HUMAN
θ value	0.00869519 (rank : 77)	NC score	0.529358 (rank : 69)
Query Neighborhood Hits	147	Target Neighborhood Hits	177	Shared Neighborhood Hits	87
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
θ value	0.0148317 (rank : 78)	NC score	0.512215 (rank : 70)
Query Neighborhood Hits	147	Target Neighborhood Hits	206	Shared Neighborhood Hits	87
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

FANCM_HUMAN
θ value	0.0330416 (rank : 79)	NC score	0.409796 (rank : 78)
Query Neighborhood Hits	147	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
θ value	0.0563607 (rank : 80)	NC score	0.406289 (rank : 79)
Query Neighborhood Hits	147	Target Neighborhood Hits	177	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

HNRPC_MOUSE
θ value	0.163984 (rank : 81)	NC score	0.017555 (rank : 107)
Query Neighborhood Hits	147	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z204, Q3TLB5, Q501Q3, Q8C2G5, Q99KE2, Q9CQT3, Q9CY83	Gene names	Hnrpc, Hnrnpc
Domain Architecture
Description	Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1 / hnRNP C2).

MP2K7_HUMAN
θ value	0.21417 (rank : 82)	NC score	-0.000790 (rank : 145)
Query Neighborhood Hits	147	Target Neighborhood Hits	833	Shared Neighborhood Hits	8
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

ZC3H3_MOUSE
θ value	0.21417 (rank : 83)	NC score	0.020309 (rank : 101)
Query Neighborhood Hits	147	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

RRBP1_HUMAN
θ value	0.279714 (rank : 84)	NC score	0.014596 (rank : 111)
Query Neighborhood Hits	147	Target Neighborhood Hits	1306	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

GOGA4_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.011453 (rank : 115)
Query Neighborhood Hits	147	Target Neighborhood Hits	2034	Shared Neighborhood Hits	41
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RRBP1_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.015916 (rank : 109)
Query Neighborhood Hits	147	Target Neighborhood Hits	1650	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ZN326_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.022397 (rank : 98)
Query Neighborhood Hits	147	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

ANC5_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.022614 (rank : 97)
Query Neighborhood Hits	147	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTZ4, Q3TGA7, Q80UJ6, Q80W43, Q8BWW7, Q8C0F7, Q9CRX0, Q9CSL1, Q9JJB8	Gene names	Anapc5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

CTRO_HUMAN
θ value	0.813845 (rank : 89)	NC score	-0.002546 (rank : 148)
Query Neighborhood Hits	147	Target Neighborhood Hits	2092	Shared Neighborhood Hits	27
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EDAR_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.023590 (rank : 96)
Query Neighborhood Hits	147	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

HRX_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.008474 (rank : 119)
Query Neighborhood Hits	147	Target Neighborhood Hits	825	Shared Neighborhood Hits	18
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

BSN_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.010002 (rank : 117)
Query Neighborhood Hits	147	Target Neighborhood Hits	1537	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GOGA4_MOUSE
θ value	1.06291 (rank : 93)	NC score	0.006569 (rank : 125)
Query Neighborhood Hits	147	Target Neighborhood Hits	1939	Shared Neighborhood Hits	33
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HCN4_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.004814 (rank : 130)
Query Neighborhood Hits	147	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

IFIH1_HUMAN
θ value	1.06291 (rank : 95)	NC score	0.301946 (rank : 82)
Query Neighborhood Hits	147	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

ATBF1_MOUSE
θ value	1.38821 (rank : 96)	NC score	-0.003057 (rank : 149)
Query Neighborhood Hits	147	Target Neighborhood Hits	1841	Shared Neighborhood Hits	28
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATX2_MOUSE
θ value	1.38821 (rank : 97)	NC score	0.015886 (rank : 110)
Query Neighborhood Hits	147	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

NFH_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.007540 (rank : 120)
Query Neighborhood Hits	147	Target Neighborhood Hits	2247	Shared Neighborhood Hits	45
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RBBP8_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.019284 (rank : 102)
Query Neighborhood Hits	147	Target Neighborhood Hits	476	Shared Neighborhood Hits	16
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

TCOF_MOUSE
θ value	1.38821 (rank : 100)	NC score	0.018673 (rank : 103)
Query Neighborhood Hits	147	Target Neighborhood Hits	471	Shared Neighborhood Hits	16
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

EDAR_MOUSE
θ value	1.81305 (rank : 101)	NC score	0.021335 (rank : 99)
Query Neighborhood Hits	147	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

LGP2_MOUSE
θ value	1.81305 (rank : 102)	NC score	0.299051 (rank : 83)
Query Neighborhood Hits	147	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

PTN5_MOUSE
θ value	1.81305 (rank : 103)	NC score	0.002619 (rank : 136)
Query Neighborhood Hits	147	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

ABL2_HUMAN
θ value	2.36792 (rank : 104)	NC score	-0.005972 (rank : 150)
Query Neighborhood Hits	147	Target Neighborhood Hits	1045	Shared Neighborhood Hits	7
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

CSKI1_MOUSE
θ value	2.36792 (rank : 105)	NC score	-0.001195 (rank : 146)
Query Neighborhood Hits	147	Target Neighborhood Hits	1031	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CTRO_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.000113 (rank : 142)
Query Neighborhood Hits	147	Target Neighborhood Hits	2344	Shared Neighborhood Hits	33
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

IFIH1_MOUSE
θ value	2.36792 (rank : 107)	NC score	0.290584 (rank : 84)
Query Neighborhood Hits	147	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

JAG2_MOUSE
θ value	2.36792 (rank : 108)	NC score	-0.001704 (rank : 147)
Query Neighborhood Hits	147	Target Neighborhood Hits	504	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

ESCO1_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.020425 (rank : 100)
Query Neighborhood Hits	147	Target Neighborhood Hits	361	Shared Neighborhood Hits	20
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

FAM9A_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.013806 (rank : 112)
Query Neighborhood Hits	147	Target Neighborhood Hits	138	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

LDB3_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.002846 (rank : 134)
Query Neighborhood Hits	147	Target Neighborhood Hits	497	Shared Neighborhood Hits	9
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

OXRP_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.004674 (rank : 131)
Query Neighborhood Hits	147	Target Neighborhood Hits	544	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

RFIP3_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.005132 (rank : 128)
Query Neighborhood Hits	147	Target Neighborhood Hits	1055	Shared Neighborhood Hits	21
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

TE2IP_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.012271 (rank : 113)
Query Neighborhood Hits	147	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

AKA12_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.017637 (rank : 106)
Query Neighborhood Hits	147	Target Neighborhood Hits	825	Shared Neighborhood Hits	28
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CC026_MOUSE
θ value	4.03905 (rank : 116)	NC score	0.139676 (rank : 89)
Query Neighborhood Hits	147	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

CG1_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.016511 (rank : 108)
Query Neighborhood Hits	147	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

FA13A_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.007318 (rank : 121)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

TBX22_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.002755 (rank : 135)
Query Neighborhood Hits	147	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

TRI16_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.006627 (rank : 124)
Query Neighborhood Hits	147	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

ANC5_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.017891 (rank : 104)
Query Neighborhood Hits	147	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJX4, Q8N4H7, Q9BQD4	Gene names	ANAPC5, APC5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

ATRX_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.017805 (rank : 105)
Query Neighborhood Hits	147	Target Neighborhood Hits	842	Shared Neighborhood Hits	31
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CING_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.003097 (rank : 133)
Query Neighborhood Hits	147	Target Neighborhood Hits	1275	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

EP400_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.004983 (rank : 129)
Query Neighborhood Hits	147	Target Neighborhood Hits	592	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FOXH1_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.001526 (rank : 140)
Query Neighborhood Hits	147	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	O88621, Q9QZL5, Q9R241	Gene names	Foxh1, Fast1, Fast2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (Forkhead activin signal transducer 2) (Fast-2).

TXND2_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.031379 (rank : 95)
Query Neighborhood Hits	147	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

JAD1A_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.001878 (rank : 139)
Query Neighborhood Hits	147	Target Neighborhood Hits	328	Shared Neighborhood Hits	10
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

LGP2_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.290104 (rank : 85)
Query Neighborhood Hits	147	Target Neighborhood Hits	94	Shared Neighborhood Hits	72
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

NIPBL_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.033965 (rank : 94)
Query Neighborhood Hits	147	Target Neighborhood Hits	1311	Shared Neighborhood Hits	38
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NR1D2_HUMAN
θ value	6.88961 (rank : 130)	NC score	-0.000216 (rank : 143)
Query Neighborhood Hits	147	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

PGCB_MOUSE
θ value	6.88961 (rank : 131)	NC score	-0.000409 (rank : 144)
Query Neighborhood Hits	147	Target Neighborhood Hits	459	Shared Neighborhood Hits	8
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

RECQ5_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.431067 (rank : 76)
Query Neighborhood Hits	147	Target Neighborhood Hits	390	Shared Neighborhood Hits	86
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

TITIN_HUMAN
θ value	6.88961 (rank : 133)	NC score	-0.007085 (rank : 152)
Query Neighborhood Hits	147	Target Neighborhood Hits	2923	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRIO_HUMAN
θ value	6.88961 (rank : 134)	NC score	-0.006150 (rank : 151)
Query Neighborhood Hits	147	Target Neighborhood Hits	1580	Shared Neighborhood Hits	18
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

U520_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.130630 (rank : 90)
Query Neighborhood Hits	147	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CO026_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.006916 (rank : 122)
Query Neighborhood Hits	147	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P656, Q8N906	Gene names	C15orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf26.

IF2P_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.008785 (rank : 118)
Query Neighborhood Hits	147	Target Neighborhood Hits	889	Shared Neighborhood Hits	30
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

LAD1_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.011427 (rank : 116)
Query Neighborhood Hits	147	Target Neighborhood Hits	391	Shared Neighborhood Hits	19
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LAP2A_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.006405 (rank : 127)
Query Neighborhood Hits	147	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q61033, Q61028	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms alpha/zeta (Thymopoietin isoforms alpha/zeta) (TP alpha/zeta).

LAP2B_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.006434 (rank : 126)
Query Neighborhood Hits	147	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q61029, Q61030, Q61031, Q61032	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms beta/delta/epsilon/gamma (Thymopoietin isoforms beta/delta/epsilon/gamma) (TP beta/delta/epsilon/gamma).

LDB3_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.001902 (rank : 138)
Query Neighborhood Hits	147	Target Neighborhood Hits	510	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MY18A_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.006629 (rank : 123)
Query Neighborhood Hits	147	Target Neighborhood Hits	1989	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PHF20_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.035804 (rank : 93)
Query Neighborhood Hits	147	Target Neighborhood Hits	513	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

RGNEF_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.002202 (rank : 137)
Query Neighborhood Hits	147	Target Neighborhood Hits	641	Shared Neighborhood Hits	15
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

TM131_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.011939 (rank : 114)
Query Neighborhood Hits	147	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

UBP47_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.001089 (rank : 141)
Query Neighborhood Hits	147	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

YLPM1_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.003211 (rank : 132)
Query Neighborhood Hits	147	Target Neighborhood Hits	505	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CC026_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.154927 (rank : 87)
Query Neighborhood Hits	147	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX58_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.151860 (rank : 88)
Query Neighborhood Hits	147	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.183158 (rank : 86)
Query Neighborhood Hits	147	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

HELC1_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.088807 (rank : 91)
Query Neighborhood Hits	147	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.069272 (rank : 92)
Query Neighborhood Hits	147	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

Hits sorted by NC score

DDX24_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	147	Target Neighborhood Hits	147	Shared Neighborhood Hits	147
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
NC score	0.992652 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	147	Target Neighborhood Hits	190	Shared Neighborhood Hits	97
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX47_MOUSE
NC score	0.952323 (rank : 3)	θ value	4.86918e-46 (rank : 4)
Query Neighborhood Hits	147	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.952062 (rank : 4)	θ value	2.18568e-46 (rank : 3)
Query Neighborhood Hits	147	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
NC score	0.948169 (rank : 5)	θ value	1.85459e-37 (rank : 6)
Query Neighborhood Hits	147	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_HUMAN
NC score	0.945779 (rank : 6)	θ value	2.58786e-39 (rank : 5)
Query Neighborhood Hits	147	Target Neighborhood Hits	223	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX27_MOUSE
NC score	0.937487 (rank : 7)	θ value	1.24399e-33 (rank : 7)
Query Neighborhood Hits	147	Target Neighborhood Hits	174	Shared Neighborhood Hits	91
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX18_MOUSE
NC score	0.936119 (rank : 8)	θ value	1.6247e-33 (rank : 8)
Query Neighborhood Hits	147	Target Neighborhood Hits	115	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX18_HUMAN
NC score	0.936024 (rank : 9)	θ value	2.77131e-33 (rank : 9)
Query Neighborhood Hits	147	Target Neighborhood Hits	124	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX55_MOUSE
NC score	0.935995 (rank : 10)	θ value	1.28732e-30 (rank : 17)
Query Neighborhood Hits	147	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX27_HUMAN
NC score	0.935638 (rank : 11)	θ value	8.06329e-33 (rank : 10)
Query Neighborhood Hits	147	Target Neighborhood Hits	197	Shared Neighborhood Hits	92
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX54_MOUSE
NC score	0.934685 (rank : 12)	θ value	5.22648e-32 (rank : 11)
Query Neighborhood Hits	147	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX55_HUMAN
NC score	0.934467 (rank : 13)	θ value	9.8567e-31 (rank : 16)
Query Neighborhood Hits	147	Target Neighborhood Hits	122	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX41_HUMAN
NC score	0.934438 (rank : 14)	θ value	1.52067e-31 (rank : 12)
Query Neighborhood Hits	147	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.934093 (rank : 15)	θ value	1.52067e-31 (rank : 13)
Query Neighborhood Hits	147	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX31_HUMAN
NC score	0.932797 (rank : 16)	θ value	5.97985e-28 (rank : 25)
Query Neighborhood Hits	147	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX28_MOUSE
NC score	0.930556 (rank : 17)	θ value	8.08199e-25 (rank : 35)
Query Neighborhood Hits	147	Target Neighborhood Hits	112	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX54_HUMAN
NC score	0.930346 (rank : 18)	θ value	3.74554e-30 (rank : 19)
Query Neighborhood Hits	147	Target Neighborhood Hits	170	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX28_HUMAN
NC score	0.928588 (rank : 19)	θ value	6.18819e-25 (rank : 34)
Query Neighborhood Hits	147	Target Neighborhood Hits	103	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX10_HUMAN
NC score	0.928125 (rank : 20)	θ value	1.6813e-30 (rank : 18)
Query Neighborhood Hits	147	Target Neighborhood Hits	210	Shared Neighborhood Hits	89
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX6_MOUSE
NC score	0.927720 (rank : 21)	θ value	4.28545e-26 (rank : 30)
Query Neighborhood Hits	147	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX6_HUMAN
NC score	0.927686 (rank : 22)	θ value	2.12685e-25 (rank : 31)
Query Neighborhood Hits	147	Target Neighborhood Hits	97	Shared Neighborhood Hits	85
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX10_MOUSE
NC score	0.927443 (rank : 23)	θ value	6.38894e-30 (rank : 20)
Query Neighborhood Hits	147	Target Neighborhood Hits	233	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX17_MOUSE
NC score	0.927242 (rank : 24)	θ value	2.59387e-31 (rank : 15)
Query Neighborhood Hits	147	Target Neighborhood Hits	105	Shared Neighborhood Hits	85
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.927107 (rank : 25)	θ value	2.59387e-31 (rank : 14)
Query Neighborhood Hits	147	Target Neighborhood Hits	104	Shared Neighborhood Hits	85
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX43_HUMAN
NC score	0.926568 (rank : 26)	θ value	3.87602e-27 (rank : 27)
Query Neighborhood Hits	147	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX48_HUMAN
NC score	0.922081 (rank : 27)	θ value	2.05525e-28 (rank : 21)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.921934 (rank : 28)	θ value	2.05525e-28 (rank : 22)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX56_HUMAN
NC score	0.920853 (rank : 29)	θ value	1.2077e-20 (rank : 57)
Query Neighborhood Hits	147	Target Neighborhood Hits	77	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX5_HUMAN
NC score	0.920380 (rank : 30)	θ value	1.12775e-26 (rank : 28)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	86
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.920360 (rank : 31)	θ value	1.12775e-26 (rank : 29)
Query Neighborhood Hits	147	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX56_MOUSE
NC score	0.919756 (rank : 32)	θ value	1.02238e-19 (rank : 60)
Query Neighborhood Hits	147	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX4_MOUSE
NC score	0.919171 (rank : 33)	θ value	7.56453e-23 (rank : 51)
Query Neighborhood Hits	147	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX39_HUMAN
NC score	0.919058 (rank : 34)	θ value	2.35151e-24 (rank : 43)
Query Neighborhood Hits	147	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX53_HUMAN
NC score	0.918840 (rank : 35)	θ value	4.43474e-23 (rank : 50)
Query Neighborhood Hits	147	Target Neighborhood Hits	124	Shared Neighborhood Hits	82
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX39_MOUSE
NC score	0.918607 (rank : 36)	θ value	1.37858e-24 (rank : 38)
Query Neighborhood Hits	147	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX4_HUMAN
NC score	0.918476 (rank : 37)	θ value	1.5242e-23 (rank : 47)
Query Neighborhood Hits	147	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

UAP56_HUMAN
NC score	0.917561 (rank : 38)	θ value	2.35151e-24 (rank : 45)
Query Neighborhood Hits	147	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.917501 (rank : 39)	θ value	2.35151e-24 (rank : 46)
Query Neighborhood Hits	147	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX51_MOUSE
NC score	0.916260 (rank : 40)	θ value	1.6852e-22 (rank : 52)
Query Neighborhood Hits	147	Target Neighborhood Hits	130	Shared Neighborhood Hits	87
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

IF4A1_HUMAN
NC score	0.916170 (rank : 41)	θ value	1.37858e-24 (rank : 39)
Query Neighborhood Hits	147	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.916170 (rank : 42)	θ value	1.37858e-24 (rank : 40)
Query Neighborhood Hits	147	Target Neighborhood Hits	106	Shared Neighborhood Hits	86
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
NC score	0.915884 (rank : 43)	θ value	1.37858e-24 (rank : 41)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.915884 (rank : 44)	θ value	1.37858e-24 (rank : 42)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	85
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX52_HUMAN
NC score	0.915585 (rank : 45)	θ value	1.47631e-18 (rank : 62)
Query Neighborhood Hits	147	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
NC score	0.914913 (rank : 46)	θ value	6.20254e-17 (rank : 65)
Query Neighborhood Hits	147	Target Neighborhood Hits	101	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX50_MOUSE
NC score	0.912741 (rank : 47)	θ value	1.5242e-23 (rank : 48)
Query Neighborhood Hits	147	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
NC score	0.912550 (rank : 48)	θ value	1.99067e-23 (rank : 49)
Query Neighborhood Hits	147	Target Neighborhood Hits	132	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX3Y_MOUSE
NC score	0.912039 (rank : 49)	θ value	2.77775e-25 (rank : 32)
Query Neighborhood Hits	147	Target Neighborhood Hits	126	Shared Neighborhood Hits	86
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX3X_HUMAN
NC score	0.911035 (rank : 50)	θ value	4.73814e-25 (rank : 33)
Query Neighborhood Hits	147	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

PL10_MOUSE
NC score	0.911011 (rank : 51)	θ value	1.05554e-24 (rank : 37)
Query Neighborhood Hits	147	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_MOUSE
NC score	0.910337 (rank : 52)	θ value	1.05554e-24 (rank : 36)
Query Neighborhood Hits	147	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX46_HUMAN
NC score	0.909471 (rank : 53)	θ value	4.57862e-28 (rank : 23)
Query Neighborhood Hits	147	Target Neighborhood Hits	357	Shared Neighborhood Hits	97
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX3Y_HUMAN
NC score	0.908534 (rank : 54)	θ value	2.35151e-24 (rank : 44)
Query Neighborhood Hits	147	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX46_MOUSE
NC score	0.907059 (rank : 55)	θ value	4.57862e-28 (rank : 24)
Query Neighborhood Hits	147	Target Neighborhood Hits	358	Shared Neighborhood Hits	96
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX20_HUMAN
NC score	0.903482 (rank : 56)	θ value	5.99374e-20 (rank : 58)
Query Neighborhood Hits	147	Target Neighborhood Hits	121	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX23_HUMAN
NC score	0.903142 (rank : 57)	θ value	2.27234e-27 (rank : 26)
Query Neighborhood Hits	147	Target Neighborhood Hits	486	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX21_HUMAN
NC score	0.901293 (rank : 58)	θ value	2.87452e-22 (rank : 53)
Query Neighborhood Hits	147	Target Neighborhood Hits	308	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX20_MOUSE
NC score	0.900362 (rank : 59)	θ value	1.33526e-19 (rank : 61)
Query Neighborhood Hits	147	Target Neighborhood Hits	177	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX51_HUMAN
NC score	0.899593 (rank : 60)	θ value	1.86321e-21 (rank : 54)
Query Neighborhood Hits	147	Target Neighborhood Hits	332	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX21_MOUSE
NC score	0.893280 (rank : 61)	θ value	4.15078e-21 (rank : 55)
Query Neighborhood Hits	147	Target Neighborhood Hits	350	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DD19A_HUMAN
NC score	0.886691 (rank : 62)	θ value	1.24977e-17 (rank : 63)
Query Neighborhood Hits	147	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.885516 (rank : 63)	θ value	3.63628e-17 (rank : 64)
Query Neighborhood Hits	147	Target Neighborhood Hits	109	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
NC score	0.884956 (rank : 64)	θ value	1.80466e-16 (rank : 66)
Query Neighborhood Hits	147	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_HUMAN
NC score	0.883068 (rank : 65)	θ value	1.09485e-13 (rank : 68)
Query Neighborhood Hits	147	Target Neighborhood Hits	93	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
NC score	0.882586 (rank : 66)	θ value	3.76295e-14 (rank : 67)
Query Neighborhood Hits	147	Target Neighborhood Hits	98	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX1_MOUSE
NC score	0.871651 (rank : 67)	θ value	1.2077e-20 (rank : 56)
Query Neighborhood Hits	147	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.870095 (rank : 68)	θ value	7.82807e-20 (rank : 59)
Query Neighborhood Hits	147	Target Neighborhood Hits	110	Shared Neighborhood Hits	84
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.529358 (rank : 69)	θ value	0.00869519 (rank : 77)
Query Neighborhood Hits	147	Target Neighborhood Hits	177	Shared Neighborhood Hits	87
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.512215 (rank : 70)	θ value	0.0148317 (rank : 78)
Query Neighborhood Hits	147	Target Neighborhood Hits	206	Shared Neighborhood Hits	87
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.487285 (rank : 71)	θ value	0.00665767 (rank : 73)
Query Neighborhood Hits	147	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.476170 (rank : 72)	θ value	0.00390308 (rank : 72)
Query Neighborhood Hits	147	Target Neighborhood Hits	148	Shared Neighborhood Hits	77
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_HUMAN
NC score	0.470188 (rank : 73)	θ value	2.44474e-05 (rank : 69)
Query Neighborhood Hits	147	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ1_MOUSE
NC score	0.436128 (rank : 74)	θ value	9.29e-05 (rank : 70)
Query Neighborhood Hits	147	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_HUMAN
NC score	0.431140 (rank : 75)	θ value	0.00869519 (rank : 76)
Query Neighborhood Hits	147	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ5_HUMAN
NC score	0.431067 (rank : 76)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	147	Target Neighborhood Hits	390	Shared Neighborhood Hits	86
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_MOUSE
NC score	0.431007 (rank : 77)	θ value	0.00134147 (rank : 71)
Query Neighborhood Hits	147	Target Neighborhood Hits	295	Shared Neighborhood Hits	84
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

FANCM_HUMAN
NC score	0.409796 (rank : 78)	θ value	0.0330416 (rank : 79)
Query Neighborhood Hits	147	Target Neighborhood Hits	210	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.406289 (rank : 79)	θ value	0.0563607 (rank : 80)
Query Neighborhood Hits	147	Target Neighborhood Hits	177	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_HUMAN
NC score	0.398745 (rank : 80)	θ value	0.00665767 (rank : 74)
Query Neighborhood Hits	147	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

DICER_MOUSE
NC score	0.397817 (rank : 81)	θ value	0.00665767 (rank : 75)
Query Neighborhood Hits	147	Target Neighborhood Hits	140	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

IFIH1_HUMAN
NC score	0.301946 (rank : 82)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	147	Target Neighborhood Hits	96	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_MOUSE
NC score	0.299051 (rank : 83)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	147	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

IFIH1_MOUSE
NC score	0.290584 (rank : 84)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	147	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

LGP2_HUMAN
NC score	0.290104 (rank : 85)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	147	Target Neighborhood Hits	94	Shared Neighborhood Hits	72
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

DDX58_MOUSE
NC score	0.183158 (rank : 86)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	147	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_HUMAN
NC score	0.154927 (rank : 87)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	147	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

DDX58_HUMAN
NC score	0.151860 (rank : 88)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	147	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

CC026_MOUSE
NC score	0.139676 (rank : 89)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	147	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

U520_HUMAN
NC score	0.130630 (rank : 90)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	147	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

HELC1_HUMAN
NC score	0.088807 (rank : 91)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	147	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

SMAL1_HUMAN
NC score	0.069272 (rank : 92)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	147	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

PHF20_MOUSE
NC score	0.035804 (rank : 93)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	147	Target Neighborhood Hits	513	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

NIPBL_HUMAN
NC score	0.033965 (rank : 94)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	147	Target Neighborhood Hits	1311	Shared Neighborhood Hits	38
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TXND2_MOUSE
NC score	0.031379 (rank : 95)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	147	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

EDAR_HUMAN
NC score	0.023590 (rank : 96)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	147	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

ANC5_MOUSE
NC score	0.022614 (rank : 97)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	147	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTZ4, Q3TGA7, Q80UJ6, Q80W43, Q8BWW7, Q8C0F7, Q9CRX0, Q9CSL1, Q9JJB8	Gene names	Anapc5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

ZN326_MOUSE
NC score	0.022397 (rank : 98)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	147	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

EDAR_MOUSE
NC score	0.021335 (rank : 99)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	147	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

ESCO1_HUMAN
NC score	0.020425 (rank : 100)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	147	Target Neighborhood Hits	361	Shared Neighborhood Hits	20
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

ZC3H3_MOUSE
NC score	0.020309 (rank : 101)	θ value	0.21417 (rank : 83)
Query Neighborhood Hits	147	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

RBBP8_HUMAN
NC score	0.019284 (rank : 102)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	147	Target Neighborhood Hits	476	Shared Neighborhood Hits	16
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

TCOF_MOUSE
NC score	0.018673 (rank : 103)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	147	Target Neighborhood Hits	471	Shared Neighborhood Hits	16
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ANC5_HUMAN
NC score	0.017891 (rank : 104)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	147	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJX4, Q8N4H7, Q9BQD4	Gene names	ANAPC5, APC5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

ATRX_HUMAN
NC score	0.017805 (rank : 105)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	147	Target Neighborhood Hits	842	Shared Neighborhood Hits	31
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

AKA12_HUMAN
NC score	0.017637 (rank : 106)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	147	Target Neighborhood Hits	825	Shared Neighborhood Hits	28
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

HNRPC_MOUSE
NC score	0.017555 (rank : 107)	θ value	0.163984 (rank : 81)
Query Neighborhood Hits	147	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z204, Q3TLB5, Q501Q3, Q8C2G5, Q99KE2, Q9CQT3, Q9CY83	Gene names	Hnrpc, Hnrnpc
Domain Architecture
Description	Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1 / hnRNP C2).

CG1_HUMAN
NC score	0.016511 (rank : 108)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	147	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

RRBP1_MOUSE
NC score	0.015916 (rank : 109)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	147	Target Neighborhood Hits	1650	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ATX2_MOUSE
NC score	0.015886 (rank : 110)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	147	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

RRBP1_HUMAN
NC score	0.014596 (rank : 111)	θ value	0.279714 (rank : 84)
Query Neighborhood Hits	147	Target Neighborhood Hits	1306	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

FAM9A_HUMAN
NC score	0.013806 (rank : 112)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	147	Target Neighborhood Hits	138	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

TE2IP_HUMAN
NC score	0.012271 (rank : 113)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	147	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYB0, Q8WYZ3, Q9NWR2	Gene names	TERF2IP, RAP1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1) (hRap1).

TM131_MOUSE
NC score	0.011939 (rank : 114)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	147	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

GOGA4_HUMAN
NC score	0.011453 (rank : 115)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	147	Target Neighborhood Hits	2034	Shared Neighborhood Hits	41
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

LAD1_MOUSE
NC score	0.011427 (rank : 116)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	147	Target Neighborhood Hits	391	Shared Neighborhood Hits	19
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

BSN_HUMAN
NC score	0.010002 (rank : 117)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	147	Target Neighborhood Hits	1537	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

IF2P_HUMAN
NC score	0.008785 (rank : 118)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	147	Target Neighborhood Hits	889	Shared Neighborhood Hits	30
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

HRX_HUMAN
NC score	0.008474 (rank : 119)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	147	Target Neighborhood Hits	825	Shared Neighborhood Hits	18
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

NFH_MOUSE
NC score	0.007540 (rank : 120)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	147	Target Neighborhood Hits	2247	Shared Neighborhood Hits	45
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

FA13A_HUMAN
NC score	0.007318 (rank : 121)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	147	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

CO026_HUMAN
NC score	0.006916 (rank : 122)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	147	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P656, Q8N906	Gene names	C15orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf26.

MY18A_MOUSE
NC score	0.006629 (rank : 123)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	147	Target Neighborhood Hits	1989	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TRI16_HUMAN
NC score	0.006627 (rank : 124)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	147	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

GOGA4_MOUSE
NC score	0.006569 (rank : 125)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	147	Target Neighborhood Hits	1939	Shared Neighborhood Hits	33
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LAP2B_MOUSE
NC score	0.006434 (rank : 126)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	147	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q61029, Q61030, Q61031, Q61032	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms beta/delta/epsilon/gamma (Thymopoietin isoforms beta/delta/epsilon/gamma) (TP beta/delta/epsilon/gamma).

LAP2A_MOUSE
NC score	0.006405 (rank : 127)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	147	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q61033, Q61028	Gene names	Tmpo, Lap2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoforms alpha/zeta (Thymopoietin isoforms alpha/zeta) (TP alpha/zeta).

RFIP3_HUMAN
NC score	0.005132 (rank : 128)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	147	Target Neighborhood Hits	1055	Shared Neighborhood Hits	21
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

EP400_MOUSE
NC score	0.004983 (rank : 129)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	147	Target Neighborhood Hits	592	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

HCN4_MOUSE
NC score	0.004814 (rank : 130)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	147	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

OXRP_HUMAN
NC score	0.004674 (rank : 131)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	147	Target Neighborhood Hits	544	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

YLPM1_MOUSE
NC score	0.003211 (rank : 132)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	147	Target Neighborhood Hits	505	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CING_HUMAN
NC score	0.003097 (rank : 133)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	147	Target Neighborhood Hits	1275	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

LDB3_HUMAN
NC score	0.002846 (rank : 134)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	147	Target Neighborhood Hits	497	Shared Neighborhood Hits	9
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

TBX22_HUMAN
NC score	0.002755 (rank : 135)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	147	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y458, Q96LC0, Q9HBF1	Gene names	TBX22, TBOX22
Domain Architecture
Description	T-box transcription factor TBX22 (T-box protein 22).

PTN5_MOUSE
NC score	0.002619 (rank : 136)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	147	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

RGNEF_MOUSE
NC score	0.002202 (rank : 137)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	147	Target Neighborhood Hits	641	Shared Neighborhood Hits	15
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

LDB3_MOUSE
NC score	0.001902 (rank : 138)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	147	Target Neighborhood Hits	510	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

JAD1A_HUMAN
NC score	0.001878 (rank : 139)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	147	Target Neighborhood Hits	328	Shared Neighborhood Hits	10
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

FOXH1_MOUSE
NC score	0.001526 (rank : 140)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	147	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	O88621, Q9QZL5, Q9R241	Gene names	Foxh1, Fast1, Fast2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (Forkhead activin signal transducer 2) (Fast-2).

UBP47_HUMAN
NC score	0.001089 (rank : 141)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	147	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

CTRO_MOUSE
NC score	0.000113 (rank : 142)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	147	Target Neighborhood Hits	2344	Shared Neighborhood Hits	33
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

NR1D2_HUMAN
NC score	-0.000216 (rank : 143)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	147	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

PGCB_MOUSE
NC score	-0.000409 (rank : 144)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	147	Target Neighborhood Hits	459	Shared Neighborhood Hits	8
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

MP2K7_HUMAN
NC score	-0.000790 (rank : 145)	θ value	0.21417 (rank : 82)
Query Neighborhood Hits	147	Target Neighborhood Hits	833	Shared Neighborhood Hits	8
SwissProt Accessions	O14733, O14648, O14816, O60452, O60453	Gene names	MAP2K7, JNKK2, MKK7, PRKMK7
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 7 (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2).

CSKI1_MOUSE
NC score	-0.001195 (rank : 146)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	147	Target Neighborhood Hits	1031	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

JAG2_MOUSE
NC score	-0.001704 (rank : 147)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	147	Target Neighborhood Hits	504	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

CTRO_HUMAN
NC score	-0.002546 (rank : 148)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	147	Target Neighborhood Hits	2092	Shared Neighborhood Hits	27
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ATBF1_MOUSE
NC score	-0.003057 (rank : 149)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	147	Target Neighborhood Hits	1841	Shared Neighborhood Hits	28
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ABL2_HUMAN
NC score	-0.005972 (rank : 150)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	147	Target Neighborhood Hits	1045	Shared Neighborhood Hits	7
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

TRIO_HUMAN
NC score	-0.006150 (rank : 151)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	147	Target Neighborhood Hits	1580	Shared Neighborhood Hits	18
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TITIN_HUMAN
NC score	-0.007085 (rank : 152)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	147	Target Neighborhood Hits	2923	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).