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Network neighborhood for query Sequence : DDX51_HUMAN

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DDX51_HUMAN
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX51_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	332	Target Neighborhood Hits	332	Shared Neighborhood Hits	332
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_MOUSE
θ value	0 (rank : 2)	NC score	0.980622 (rank : 2)
Query Neighborhood Hits	332	Target Neighborhood Hits	130	Shared Neighborhood Hits	99
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX27_MOUSE
θ value	2.58187e-47 (rank : 3)	NC score	0.936834 (rank : 3)
Query Neighborhood Hits	332	Target Neighborhood Hits	174	Shared Neighborhood Hits	90
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
θ value	5.95217e-44 (rank : 4)	NC score	0.934128 (rank : 6)
Query Neighborhood Hits	332	Target Neighborhood Hits	197	Shared Neighborhood Hits	88
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX47_MOUSE
θ value	1.79215e-40 (rank : 5)	NC score	0.934821 (rank : 4)
Query Neighborhood Hits	332	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_MOUSE
θ value	1.51715e-39 (rank : 6)	NC score	0.933848 (rank : 7)
Query Neighborhood Hits	332	Target Neighborhood Hits	119	Shared Neighborhood Hits	90
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX47_HUMAN
θ value	1.98146e-39 (rank : 7)	NC score	0.934183 (rank : 5)
Query Neighborhood Hits	332	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
θ value	5.76516e-39 (rank : 8)	NC score	0.931194 (rank : 8)
Query Neighborhood Hits	332	Target Neighborhood Hits	223	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX10_HUMAN
θ value	1.9192e-34 (rank : 9)	NC score	0.920623 (rank : 16)
Query Neighborhood Hits	332	Target Neighborhood Hits	210	Shared Neighborhood Hits	87
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	3.27365e-34 (rank : 10)	NC score	0.920169 (rank : 17)
Query Neighborhood Hits	332	Target Neighborhood Hits	233	Shared Neighborhood Hits	88
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX18_MOUSE
θ value	7.29293e-34 (rank : 11)	NC score	0.925928 (rank : 9)
Query Neighborhood Hits	332	Target Neighborhood Hits	115	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX52_HUMAN
θ value	4.72714e-33 (rank : 12)	NC score	0.924370 (rank : 13)
Query Neighborhood Hits	332	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
θ value	6.17384e-33 (rank : 13)	NC score	0.924430 (rank : 12)
Query Neighborhood Hits	332	Target Neighborhood Hits	101	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX18_HUMAN
θ value	2.34606e-32 (rank : 14)	NC score	0.924453 (rank : 11)
Query Neighborhood Hits	332	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX55_HUMAN
θ value	9.8567e-31 (rank : 15)	NC score	0.922563 (rank : 15)
Query Neighborhood Hits	332	Target Neighborhood Hits	122	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	3.74554e-30 (rank : 16)	NC score	0.923523 (rank : 14)
Query Neighborhood Hits	332	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX31_HUMAN
θ value	4.14116e-29 (rank : 17)	NC score	0.924953 (rank : 10)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX46_HUMAN
θ value	4.14116e-29 (rank : 18)	NC score	0.895560 (rank : 42)
Query Neighborhood Hits	332	Target Neighborhood Hits	357	Shared Neighborhood Hits	109
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	4.14116e-29 (rank : 19)	NC score	0.893161 (rank : 48)
Query Neighborhood Hits	332	Target Neighborhood Hits	358	Shared Neighborhood Hits	107
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX21_MOUSE
θ value	5.40856e-29 (rank : 20)	NC score	0.895114 (rank : 43)
Query Neighborhood Hits	332	Target Neighborhood Hits	350	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX56_MOUSE
θ value	5.40856e-29 (rank : 21)	NC score	0.918144 (rank : 19)
Query Neighborhood Hits	332	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX23_HUMAN
θ value	2.05525e-28 (rank : 22)	NC score	0.885936 (rank : 59)
Query Neighborhood Hits	332	Target Neighborhood Hits	486	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX56_HUMAN
θ value	3.50572e-28 (rank : 23)	NC score	0.918273 (rank : 18)
Query Neighborhood Hits	332	Target Neighborhood Hits	77	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX50_MOUSE
θ value	4.57862e-28 (rank : 24)	NC score	0.907365 (rank : 29)
Query Neighborhood Hits	332	Target Neighborhood Hits	137	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX21_HUMAN
θ value	5.97985e-28 (rank : 25)	NC score	0.897213 (rank : 38)
Query Neighborhood Hits	332	Target Neighborhood Hits	308	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX50_HUMAN
θ value	7.80994e-28 (rank : 26)	NC score	0.907235 (rank : 31)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX41_HUMAN
θ value	1.02001e-27 (rank : 27)	NC score	0.914494 (rank : 20)
Query Neighborhood Hits	332	Target Neighborhood Hits	111	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	1.33217e-27 (rank : 28)	NC score	0.914111 (rank : 21)
Query Neighborhood Hits	332	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX4_HUMAN
θ value	1.73987e-27 (rank : 29)	NC score	0.908647 (rank : 26)
Query Neighborhood Hits	332	Target Neighborhood Hits	123	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	5.06226e-27 (rank : 30)	NC score	0.909256 (rank : 25)
Query Neighborhood Hits	332	Target Neighborhood Hits	100	Shared Neighborhood Hits	90
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX54_HUMAN
θ value	3.28125e-26 (rank : 31)	NC score	0.911196 (rank : 24)
Query Neighborhood Hits	332	Target Neighborhood Hits	170	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX54_MOUSE
θ value	5.59698e-26 (rank : 32)	NC score	0.913958 (rank : 22)
Query Neighborhood Hits	332	Target Neighborhood Hits	124	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX17_HUMAN
θ value	3.62785e-25 (rank : 33)	NC score	0.901882 (rank : 34)
Query Neighborhood Hits	332	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	3.62785e-25 (rank : 34)	NC score	0.902036 (rank : 33)
Query Neighborhood Hits	332	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX43_HUMAN
θ value	4.01107e-24 (rank : 35)	NC score	0.905760 (rank : 32)
Query Neighborhood Hits	332	Target Neighborhood Hits	120	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX3X_HUMAN
θ value	1.6852e-22 (rank : 36)	NC score	0.891408 (rank : 50)
Query Neighborhood Hits	332	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX28_MOUSE
θ value	3.75424e-22 (rank : 37)	NC score	0.911862 (rank : 23)
Query Neighborhood Hits	332	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

PL10_MOUSE
θ value	3.75424e-22 (rank : 38)	NC score	0.891418 (rank : 49)
Query Neighborhood Hits	332	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX24_HUMAN
θ value	1.86321e-21 (rank : 39)	NC score	0.897591 (rank : 37)
Query Neighborhood Hits	332	Target Neighborhood Hits	190	Shared Neighborhood Hits	98
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_MOUSE
θ value	1.86321e-21 (rank : 40)	NC score	0.899593 (rank : 35)
Query Neighborhood Hits	332	Target Neighborhood Hits	147	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX28_HUMAN
θ value	1.86321e-21 (rank : 41)	NC score	0.907942 (rank : 27)
Query Neighborhood Hits	332	Target Neighborhood Hits	103	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX39_HUMAN
θ value	1.86321e-21 (rank : 42)	NC score	0.899005 (rank : 36)
Query Neighborhood Hits	332	Target Neighborhood Hits	94	Shared Neighborhood Hits	87
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX3X_MOUSE
θ value	1.86321e-21 (rank : 43)	NC score	0.890275 (rank : 53)
Query Neighborhood Hits	332	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

IF4A2_HUMAN
θ value	2.43343e-21 (rank : 44)	NC score	0.894381 (rank : 46)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	2.43343e-21 (rank : 45)	NC score	0.894381 (rank : 47)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DD19A_HUMAN
θ value	7.0802e-21 (rank : 46)	NC score	0.881574 (rank : 63)
Query Neighborhood Hits	332	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX3Y_HUMAN
θ value	9.24701e-21 (rank : 47)	NC score	0.888805 (rank : 55)
Query Neighborhood Hits	332	Target Neighborhood Hits	121	Shared Neighborhood Hits	88
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX3Y_MOUSE
θ value	9.24701e-21 (rank : 48)	NC score	0.891371 (rank : 51)
Query Neighborhood Hits	332	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

IF4A1_HUMAN
θ value	1.2077e-20 (rank : 49)	NC score	0.894625 (rank : 44)
Query Neighborhood Hits	332	Target Neighborhood Hits	106	Shared Neighborhood Hits	88
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	1.2077e-20 (rank : 50)	NC score	0.894625 (rank : 45)
Query Neighborhood Hits	332	Target Neighborhood Hits	106	Shared Neighborhood Hits	88
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DD19A_MOUSE
θ value	1.5773e-20 (rank : 51)	NC score	0.880999 (rank : 65)
Query Neighborhood Hits	332	Target Neighborhood Hits	105	Shared Neighborhood Hits	86
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX25_MOUSE
θ value	2.06002e-20 (rank : 52)	NC score	0.882144 (rank : 62)
Query Neighborhood Hits	332	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19B_HUMAN
θ value	2.69047e-20 (rank : 53)	NC score	0.880571 (rank : 66)
Query Neighborhood Hits	332	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

UAP56_HUMAN
θ value	2.69047e-20 (rank : 54)	NC score	0.895868 (rank : 40)
Query Neighborhood Hits	332	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	2.69047e-20 (rank : 55)	NC score	0.895842 (rank : 41)
Query Neighborhood Hits	332	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX6_HUMAN
θ value	3.51386e-20 (rank : 56)	NC score	0.907387 (rank : 28)
Query Neighborhood Hits	332	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	3.51386e-20 (rank : 57)	NC score	0.907267 (rank : 30)
Query Neighborhood Hits	332	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX39_MOUSE
θ value	4.58923e-20 (rank : 58)	NC score	0.896826 (rank : 39)
Query Neighborhood Hits	332	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX25_HUMAN
θ value	5.99374e-20 (rank : 59)	NC score	0.882323 (rank : 61)
Query Neighborhood Hits	332	Target Neighborhood Hits	93	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX20_MOUSE
θ value	6.62687e-19 (rank : 60)	NC score	0.881474 (rank : 64)
Query Neighborhood Hits	332	Target Neighborhood Hits	177	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX20_HUMAN
θ value	5.60996e-18 (rank : 61)	NC score	0.882423 (rank : 60)
Query Neighborhood Hits	332	Target Neighborhood Hits	121	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX5_HUMAN
θ value	2.88119e-14 (rank : 62)	NC score	0.887985 (rank : 56)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
θ value	2.88119e-14 (rank : 63)	NC score	0.887864 (rank : 57)
Query Neighborhood Hits	332	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX1_HUMAN
θ value	7.84624e-12 (rank : 64)	NC score	0.836050 (rank : 68)
Query Neighborhood Hits	332	Target Neighborhood Hits	110	Shared Neighborhood Hits	84
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

DDX1_MOUSE
θ value	7.84624e-12 (rank : 65)	NC score	0.837418 (rank : 67)
Query Neighborhood Hits	332	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX48_HUMAN
θ value	7.84624e-12 (rank : 66)	NC score	0.890544 (rank : 52)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	7.84624e-12 (rank : 67)	NC score	0.890262 (rank : 54)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX53_HUMAN
θ value	2.28291e-11 (rank : 68)	NC score	0.887574 (rank : 58)
Query Neighborhood Hits	332	Target Neighborhood Hits	124	Shared Neighborhood Hits	84
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

RECQ4_HUMAN
θ value	1.09739e-05 (rank : 69)	NC score	0.536650 (rank : 69)
Query Neighborhood Hits	332	Target Neighborhood Hits	177	Shared Neighborhood Hits	98
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

FANCM_MOUSE
θ value	1.87187e-05 (rank : 70)	NC score	0.448608 (rank : 75)
Query Neighborhood Hits	332	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

LGP2_HUMAN
θ value	0.000121331 (rank : 71)	NC score	0.347145 (rank : 83)
Query Neighborhood Hits	332	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

CSKI2_HUMAN
θ value	0.000158464 (rank : 72)	NC score	0.021097 (rank : 178)
Query Neighborhood Hits	332	Target Neighborhood Hits	747	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FANCM_HUMAN
θ value	0.000158464 (rank : 73)	NC score	0.449193 (rank : 73)
Query Neighborhood Hits	332	Target Neighborhood Hits	210	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

GNAS1_HUMAN
θ value	0.000270298 (rank : 74)	NC score	0.024898 (rank : 162)
Query Neighborhood Hits	332	Target Neighborhood Hits	278	Shared Neighborhood Hits	41
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

RECQ5_HUMAN
θ value	0.000270298 (rank : 75)	NC score	0.459950 (rank : 72)
Query Neighborhood Hits	332	Target Neighborhood Hits	390	Shared Neighborhood Hits	128
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

NFH_MOUSE
θ value	0.000602161 (rank : 76)	NC score	0.047592 (rank : 105)
Query Neighborhood Hits	332	Target Neighborhood Hits	2247	Shared Neighborhood Hits	170
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DICER_MOUSE
θ value	0.00509761 (rank : 77)	NC score	0.409479 (rank : 80)
Query Neighborhood Hits	332	Target Neighborhood Hits	140	Shared Neighborhood Hits	85
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

RECQ4_MOUSE
θ value	0.00509761 (rank : 78)	NC score	0.507098 (rank : 70)
Query Neighborhood Hits	332	Target Neighborhood Hits	206	Shared Neighborhood Hits	93
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

WRN_HUMAN
θ value	0.00509761 (rank : 79)	NC score	0.446955 (rank : 76)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

DICER_HUMAN
θ value	0.00665767 (rank : 80)	NC score	0.408953 (rank : 81)
Query Neighborhood Hits	332	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

OGFR_HUMAN
θ value	0.00665767 (rank : 81)	NC score	0.056796 (rank : 101)
Query Neighborhood Hits	332	Target Neighborhood Hits	1582	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

LGP2_MOUSE
θ value	0.00869519 (rank : 82)	NC score	0.349288 (rank : 82)
Query Neighborhood Hits	332	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

NEUM_HUMAN
θ value	0.00869519 (rank : 83)	NC score	0.074106 (rank : 93)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
θ value	0.00869519 (rank : 84)	NC score	0.071812 (rank : 94)
Query Neighborhood Hits	332	Target Neighborhood Hits	149	Shared Neighborhood Hits	27
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

WRN_MOUSE
θ value	0.0113563 (rank : 85)	NC score	0.411891 (rank : 79)
Query Neighborhood Hits	332	Target Neighborhood Hits	295	Shared Neighborhood Hits	86
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CLIC6_HUMAN
θ value	0.0148317 (rank : 86)	NC score	0.046166 (rank : 108)
Query Neighborhood Hits	332	Target Neighborhood Hits	289	Shared Neighborhood Hits	73
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

ASXL1_HUMAN
θ value	0.0193708 (rank : 87)	NC score	0.041714 (rank : 113)
Query Neighborhood Hits	332	Target Neighborhood Hits	260	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

RECQ1_MOUSE
θ value	0.0252991 (rank : 88)	NC score	0.413366 (rank : 77)
Query Neighborhood Hits	332	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

ZN385_HUMAN
θ value	0.0252991 (rank : 89)	NC score	0.042788 (rank : 111)
Query Neighborhood Hits	332	Target Neighborhood Hits	614	Shared Neighborhood Hits	78
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

IFIH1_HUMAN
θ value	0.0330416 (rank : 90)	NC score	0.340746 (rank : 84)
Query Neighborhood Hits	332	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

ANK2_HUMAN
θ value	0.0431538 (rank : 91)	NC score	0.017511 (rank : 195)
Query Neighborhood Hits	332	Target Neighborhood Hits	1615	Shared Neighborhood Hits	106
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RECQ1_HUMAN
θ value	0.0431538 (rank : 92)	NC score	0.412557 (rank : 78)
Query Neighborhood Hits	332	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

BLM_HUMAN
θ value	0.0563607 (rank : 93)	NC score	0.449148 (rank : 74)
Query Neighborhood Hits	332	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

BLM_MOUSE
θ value	0.0563607 (rank : 94)	NC score	0.461905 (rank : 71)
Query Neighborhood Hits	332	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

IWS1_MOUSE
θ value	0.0563607 (rank : 95)	NC score	0.059832 (rank : 99)
Query Neighborhood Hits	332	Target Neighborhood Hits	1258	Shared Neighborhood Hits	115
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SON_HUMAN
θ value	0.0563607 (rank : 96)	NC score	0.030361 (rank : 138)
Query Neighborhood Hits	332	Target Neighborhood Hits	1568	Shared Neighborhood Hits	106
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BASP_HUMAN
θ value	0.0736092 (rank : 97)	NC score	0.069865 (rank : 95)
Query Neighborhood Hits	332	Target Neighborhood Hits	321	Shared Neighborhood Hits	58
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DDX58_MOUSE
θ value	0.0736092 (rank : 98)	NC score	0.234415 (rank : 86)
Query Neighborhood Hits	332	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

MARCS_MOUSE
θ value	0.0736092 (rank : 99)	NC score	0.064925 (rank : 97)
Query Neighborhood Hits	332	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

SRCA_HUMAN
θ value	0.0736092 (rank : 100)	NC score	0.036467 (rank : 119)
Query Neighborhood Hits	332	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TMAP1_HUMAN
θ value	0.0736092 (rank : 101)	NC score	0.082430 (rank : 92)
Query Neighborhood Hits	332	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

ARHG1_HUMAN
θ value	0.0961366 (rank : 102)	NC score	0.014948 (rank : 214)
Query Neighborhood Hits	332	Target Neighborhood Hits	176	Shared Neighborhood Hits	25
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

U520_HUMAN
θ value	0.0961366 (rank : 103)	NC score	0.175661 (rank : 88)
Query Neighborhood Hits	332	Target Neighborhood Hits	88	Shared Neighborhood Hits	48
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

ABL1_HUMAN
θ value	0.163984 (rank : 104)	NC score	-0.003383 (rank : 325)
Query Neighborhood Hits	332	Target Neighborhood Hits	1220	Shared Neighborhood Hits	47
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BASP_MOUSE
θ value	0.163984 (rank : 105)	NC score	0.061396 (rank : 98)
Query Neighborhood Hits	332	Target Neighborhood Hits	260	Shared Neighborhood Hits	46
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CN155_HUMAN
θ value	0.163984 (rank : 106)	NC score	0.047357 (rank : 107)
Query Neighborhood Hits	332	Target Neighborhood Hits	385	Shared Neighborhood Hits	42
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

COBA1_MOUSE
θ value	0.163984 (rank : 107)	NC score	0.033288 (rank : 130)
Query Neighborhood Hits	332	Target Neighborhood Hits	487	Shared Neighborhood Hits	63
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

HELC1_HUMAN
θ value	0.163984 (rank : 108)	NC score	0.133322 (rank : 90)
Query Neighborhood Hits	332	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

RGS3_HUMAN
θ value	0.163984 (rank : 109)	NC score	0.029145 (rank : 143)
Query Neighborhood Hits	332	Target Neighborhood Hits	1375	Shared Neighborhood Hits	129
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SCND1_HUMAN
θ value	0.163984 (rank : 110)	NC score	0.011113 (rank : 244)
Query Neighborhood Hits	332	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	P57086	Gene names	SCAND1, SDP1
Domain Architecture
Description	SCAN domain-containing protein 1.

SH3BG_MOUSE
θ value	0.163984 (rank : 111)	NC score	0.029465 (rank : 142)
Query Neighborhood Hits	332	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUZ7	Gene names	Sh3bgr
Domain Architecture
Description	SH3 domain-binding glutamic acid-rich protein (SH3BGR protein).

TULP1_MOUSE
θ value	0.163984 (rank : 112)	NC score	0.023588 (rank : 167)
Query Neighborhood Hits	332	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

MYLK2_HUMAN
θ value	0.21417 (rank : 113)	NC score	-0.000954 (rank : 315)
Query Neighborhood Hits	332	Target Neighborhood Hits	920	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

IF39_MOUSE
θ value	0.279714 (rank : 114)	NC score	0.037096 (rank : 116)
Query Neighborhood Hits	332	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

INAR2_MOUSE
θ value	0.279714 (rank : 115)	NC score	0.026708 (rank : 154)
Query Neighborhood Hits	332	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O35664, O35238, O35663, O35983	Gene names	Ifnar2
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor beta chain precursor (IFN-alpha-REC) (Type I interferon receptor) (IFN-R) (Interferon alpha/beta receptor 2).

AKA12_HUMAN
θ value	0.365318 (rank : 116)	NC score	0.048161 (rank : 104)
Query Neighborhood Hits	332	Target Neighborhood Hits	825	Shared Neighborhood Hits	75
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

COAA1_MOUSE
θ value	0.365318 (rank : 117)	NC score	0.028451 (rank : 147)
Query Neighborhood Hits	332	Target Neighborhood Hits	286	Shared Neighborhood Hits	40
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

EGLN2_MOUSE
θ value	0.365318 (rank : 118)	NC score	0.015525 (rank : 208)
Query Neighborhood Hits	332	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YE2, Q8C6I4, Q8CIL9, Q8VHJ1, Q99MI0	Gene names	Egln2
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (Falkor).

IFIH1_MOUSE
θ value	0.365318 (rank : 119)	NC score	0.326096 (rank : 85)
Query Neighborhood Hits	332	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

PWWP2_HUMAN
θ value	0.365318 (rank : 120)	NC score	0.029501 (rank : 141)
Query Neighborhood Hits	332	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

CTDP1_MOUSE
θ value	0.47712 (rank : 121)	NC score	0.034181 (rank : 126)
Query Neighborhood Hits	332	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

HXC11_HUMAN
θ value	0.47712 (rank : 122)	NC score	0.004601 (rank : 286)
Query Neighborhood Hits	332	Target Neighborhood Hits	349	Shared Neighborhood Hits	14
SwissProt Accessions	O43248, Q96DH2	Gene names	HOXC11
Domain Architecture
Description	Homeobox protein Hox-C11.

INOC1_HUMAN
θ value	0.47712 (rank : 123)	NC score	0.018280 (rank : 189)
Query Neighborhood Hits	332	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

NFL_MOUSE
θ value	0.47712 (rank : 124)	NC score	0.009217 (rank : 255)
Query Neighborhood Hits	332	Target Neighborhood Hits	695	Shared Neighborhood Hits	30
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

SPEG_MOUSE
θ value	0.47712 (rank : 125)	NC score	0.003737 (rank : 292)
Query Neighborhood Hits	332	Target Neighborhood Hits	1959	Shared Neighborhood Hits	94
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZN326_MOUSE
θ value	0.47712 (rank : 126)	NC score	0.025446 (rank : 160)
Query Neighborhood Hits	332	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

CO3A1_MOUSE
θ value	0.62314 (rank : 127)	NC score	0.035731 (rank : 122)
Query Neighborhood Hits	332	Target Neighborhood Hits	466	Shared Neighborhood Hits	59
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

DMP1_MOUSE
θ value	0.62314 (rank : 128)	NC score	0.027243 (rank : 153)
Query Neighborhood Hits	332	Target Neighborhood Hits	498	Shared Neighborhood Hits	45
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

ENAH_MOUSE
θ value	0.62314 (rank : 129)	NC score	0.019174 (rank : 184)
Query Neighborhood Hits	332	Target Neighborhood Hits	919	Shared Neighborhood Hits	51
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

INOC1_MOUSE
θ value	0.62314 (rank : 130)	NC score	0.017759 (rank : 193)
Query Neighborhood Hits	332	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

TAF4_HUMAN
θ value	0.62314 (rank : 131)	NC score	0.032861 (rank : 131)
Query Neighborhood Hits	332	Target Neighborhood Hits	687	Shared Neighborhood Hits	51
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CABP4_HUMAN
θ value	0.813845 (rank : 132)	NC score	0.006510 (rank : 274)
Query Neighborhood Hits	332	Target Neighborhood Hits	250	Shared Neighborhood Hits	16
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CMGA_HUMAN
θ value	0.813845 (rank : 133)	NC score	0.047562 (rank : 106)
Query Neighborhood Hits	332	Target Neighborhood Hits	238	Shared Neighborhood Hits	33
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

CO1A1_MOUSE
θ value	0.813845 (rank : 134)	NC score	0.036741 (rank : 118)
Query Neighborhood Hits	332	Target Neighborhood Hits	457	Shared Neighborhood Hits	66
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COBA2_MOUSE
θ value	0.813845 (rank : 135)	NC score	0.030218 (rank : 139)
Query Neighborhood Hits	332	Target Neighborhood Hits	501	Shared Neighborhood Hits	63
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

ESPL1_HUMAN
θ value	0.813845 (rank : 136)	NC score	0.017790 (rank : 192)
Query Neighborhood Hits	332	Target Neighborhood Hits	95	Shared Neighborhood Hits	15
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

IQEC3_HUMAN
θ value	0.813845 (rank : 137)	NC score	0.012279 (rank : 232)
Query Neighborhood Hits	332	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

NFM_HUMAN
θ value	0.813845 (rank : 138)	NC score	0.011928 (rank : 235)
Query Neighborhood Hits	332	Target Neighborhood Hits	1328	Shared Neighborhood Hits	65
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RFIP3_HUMAN
θ value	0.813845 (rank : 139)	NC score	0.011668 (rank : 237)
Query Neighborhood Hits	332	Target Neighborhood Hits	1055	Shared Neighborhood Hits	51
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

ADDA_HUMAN
θ value	1.06291 (rank : 140)	NC score	0.013284 (rank : 225)
Query Neighborhood Hits	332	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

DMRT2_HUMAN
θ value	1.06291 (rank : 141)	NC score	0.021459 (rank : 176)
Query Neighborhood Hits	332	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5R5	Gene names	DMRT2, DSXL2
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2).

FARP1_HUMAN
θ value	1.06291 (rank : 142)	NC score	0.005072 (rank : 284)
Query Neighborhood Hits	332	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FMN1B_MOUSE
θ value	1.06291 (rank : 143)	NC score	0.024860 (rank : 163)
Query Neighborhood Hits	332	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

HDGF_MOUSE
θ value	1.06291 (rank : 144)	NC score	0.016041 (rank : 204)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

HXB4_MOUSE
θ value	1.06291 (rank : 145)	NC score	0.002451 (rank : 299)
Query Neighborhood Hits	332	Target Neighborhood Hits	375	Shared Neighborhood Hits	15
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

IWS1_HUMAN
θ value	1.06291 (rank : 146)	NC score	0.056645 (rank : 102)
Query Neighborhood Hits	332	Target Neighborhood Hits	1241	Shared Neighborhood Hits	106
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MILK1_HUMAN
θ value	1.06291 (rank : 147)	NC score	0.014897 (rank : 215)
Query Neighborhood Hits	332	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NHS_HUMAN
θ value	1.06291 (rank : 148)	NC score	0.029701 (rank : 140)
Query Neighborhood Hits	332	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

PTSS2_HUMAN
θ value	1.06291 (rank : 149)	NC score	0.014758 (rank : 219)
Query Neighborhood Hits	332	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BVG9	Gene names	PTDSS2, PSS2
Domain Architecture
Description	Phosphatidylserine synthase 2 (EC 2.7.8.-) (PtdSer synthase 2) (PSS-2) (Serine-exchange enzyme II).

RIMB1_HUMAN
θ value	1.06291 (rank : 150)	NC score	0.016149 (rank : 203)
Query Neighborhood Hits	332	Target Neighborhood Hits	1479	Shared Neighborhood Hits	96
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ANR47_HUMAN
θ value	1.38821 (rank : 151)	NC score	0.009633 (rank : 254)
Query Neighborhood Hits	332	Target Neighborhood Hits	369	Shared Neighborhood Hits	20
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

CLIC6_MOUSE
θ value	1.38821 (rank : 152)	NC score	0.023486 (rank : 169)
Query Neighborhood Hits	332	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CO4A4_HUMAN
θ value	1.38821 (rank : 153)	NC score	0.026400 (rank : 156)
Query Neighborhood Hits	332	Target Neighborhood Hits	440	Shared Neighborhood Hits	57
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

GFI1_HUMAN
θ value	1.38821 (rank : 154)	NC score	-0.006298 (rank : 335)
Query Neighborhood Hits	332	Target Neighborhood Hits	726	Shared Neighborhood Hits	17
SwissProt Accessions	Q99684, Q8N564	Gene names	GFI1, ZNF163
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

H6ST3_HUMAN
θ value	1.38821 (rank : 155)	NC score	0.012745 (rank : 229)
Query Neighborhood Hits	332	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

JADE2_HUMAN
θ value	1.38821 (rank : 156)	NC score	0.010890 (rank : 247)
Query Neighborhood Hits	332	Target Neighborhood Hits	199	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

KI13B_HUMAN
θ value	1.38821 (rank : 157)	NC score	0.004402 (rank : 287)
Query Neighborhood Hits	332	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

MY18B_HUMAN
θ value	1.38821 (rank : 158)	NC score	0.015949 (rank : 205)
Query Neighborhood Hits	332	Target Neighborhood Hits	1299	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYPC2_HUMAN
θ value	1.38821 (rank : 159)	NC score	0.007088 (rank : 270)
Query Neighborhood Hits	332	Target Neighborhood Hits	316	Shared Neighborhood Hits	9
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NFM_MOUSE
θ value	1.38821 (rank : 160)	NC score	0.008596 (rank : 257)
Query Neighborhood Hits	332	Target Neighborhood Hits	1159	Shared Neighborhood Hits	46
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

OBSCN_HUMAN
θ value	1.38821 (rank : 161)	NC score	-0.001573 (rank : 319)
Query Neighborhood Hits	332	Target Neighborhood Hits	1931	Shared Neighborhood Hits	81
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

RP1L1_HUMAN
θ value	1.38821 (rank : 162)	NC score	0.041152 (rank : 114)
Query Neighborhood Hits	332	Target Neighborhood Hits	1072	Shared Neighborhood Hits	127
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SYTL1_HUMAN
θ value	1.38821 (rank : 163)	NC score	0.010558 (rank : 249)
Query Neighborhood Hits	332	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

ZBT40_HUMAN
θ value	1.38821 (rank : 164)	NC score	-0.005920 (rank : 333)
Query Neighborhood Hits	332	Target Neighborhood Hits	949	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

CO2A1_HUMAN
θ value	1.81305 (rank : 165)	NC score	0.033555 (rank : 129)
Query Neighborhood Hits	332	Target Neighborhood Hits	486	Shared Neighborhood Hits	61
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO3A1_HUMAN
θ value	1.81305 (rank : 166)	NC score	0.035501 (rank : 124)
Query Neighborhood Hits	332	Target Neighborhood Hits	452	Shared Neighborhood Hits	62
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COAA1_HUMAN
θ value	1.81305 (rank : 167)	NC score	0.027313 (rank : 152)
Query Neighborhood Hits	332	Target Neighborhood Hits	316	Shared Neighborhood Hits	51
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COIA1_MOUSE
θ value	1.81305 (rank : 168)	NC score	0.026562 (rank : 155)
Query Neighborhood Hits	332	Target Neighborhood Hits	481	Shared Neighborhood Hits	59
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COPT2_HUMAN
θ value	1.81305 (rank : 169)	NC score	0.018375 (rank : 188)
Query Neighborhood Hits	332	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O15432	Gene names	SLC31A2, COPT2, CTR2
Domain Architecture
Description	Probable low-affinity copper uptake protein 2 (hCTR2) (Copper transporter 2) (Solute carrier family 31 member 2).

CTDP1_HUMAN
θ value	1.81305 (rank : 170)	NC score	0.040917 (rank : 115)
Query Neighborhood Hits	332	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DDX58_HUMAN
θ value	1.81305 (rank : 171)	NC score	0.194360 (rank : 87)
Query Neighborhood Hits	332	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DHX33_MOUSE
θ value	1.81305 (rank : 172)	NC score	0.017326 (rank : 196)
Query Neighborhood Hits	332	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DNMT1_HUMAN
θ value	1.81305 (rank : 173)	NC score	0.028879 (rank : 144)
Query Neighborhood Hits	332	Target Neighborhood Hits	401	Shared Neighborhood Hits	36
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

FOG1_HUMAN
θ value	1.81305 (rank : 174)	NC score	0.002807 (rank : 297)
Query Neighborhood Hits	332	Target Neighborhood Hits	981	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

IF39_HUMAN
θ value	1.81305 (rank : 175)	NC score	0.035725 (rank : 123)
Query Neighborhood Hits	332	Target Neighborhood Hits	187	Shared Neighborhood Hits	21
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

LDB3_HUMAN
θ value	1.81305 (rank : 176)	NC score	0.008163 (rank : 260)
Query Neighborhood Hits	332	Target Neighborhood Hits	497	Shared Neighborhood Hits	24
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MARCS_HUMAN
θ value	1.81305 (rank : 177)	NC score	0.051301 (rank : 103)
Query Neighborhood Hits	332	Target Neighborhood Hits	204	Shared Neighborhood Hits	36
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

PRRT3_HUMAN
θ value	1.81305 (rank : 178)	NC score	0.033807 (rank : 127)
Query Neighborhood Hits	332	Target Neighborhood Hits	998	Shared Neighborhood Hits	102
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PTMS_HUMAN
θ value	1.81305 (rank : 179)	NC score	0.030436 (rank : 137)
Query Neighborhood Hits	332	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

SRRM2_MOUSE
θ value	1.81305 (rank : 180)	NC score	0.036418 (rank : 120)
Query Neighborhood Hits	332	Target Neighborhood Hits	1470	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TMAP1_MOUSE
θ value	1.81305 (rank : 181)	NC score	0.044293 (rank : 110)
Query Neighborhood Hits	332	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CZH7, Q8C6F8	Gene names	Tmap1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TRI17_HUMAN
θ value	1.81305 (rank : 182)	NC score	-0.000147 (rank : 312)
Query Neighborhood Hits	332	Target Neighborhood Hits	318	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

ZN750_HUMAN
θ value	1.81305 (rank : 183)	NC score	0.017304 (rank : 197)
Query Neighborhood Hits	332	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ASXL1_MOUSE
θ value	2.36792 (rank : 184)	NC score	0.030961 (rank : 136)
Query Neighborhood Hits	332	Target Neighborhood Hits	182	Shared Neighborhood Hits	20
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BCL7A_MOUSE
θ value	2.36792 (rank : 185)	NC score	0.018487 (rank : 186)
Query Neighborhood Hits	332	Target Neighborhood Hits	74	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

BSCL2_HUMAN
θ value	2.36792 (rank : 186)	NC score	0.022544 (rank : 172)
Query Neighborhood Hits	332	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

CO1A1_HUMAN
θ value	2.36792 (rank : 187)	NC score	0.035275 (rank : 125)
Query Neighborhood Hits	332	Target Neighborhood Hits	475	Shared Neighborhood Hits	62
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO2A1_MOUSE
θ value	2.36792 (rank : 188)	NC score	0.031691 (rank : 132)
Query Neighborhood Hits	332	Target Neighborhood Hits	483	Shared Neighborhood Hits	59
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CUTL1_MOUSE
θ value	2.36792 (rank : 189)	NC score	0.005794 (rank : 279)
Query Neighborhood Hits	332	Target Neighborhood Hits	1620	Shared Neighborhood Hits	74
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DHX33_HUMAN
θ value	2.36792 (rank : 190)	NC score	0.015891 (rank : 206)
Query Neighborhood Hits	332	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

GNAS1_MOUSE
θ value	2.36792 (rank : 191)	NC score	0.022321 (rank : 173)
Query Neighborhood Hits	332	Target Neighborhood Hits	651	Shared Neighborhood Hits	65
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IF4B_HUMAN
θ value	2.36792 (rank : 192)	NC score	0.019337 (rank : 183)
Query Neighborhood Hits	332	Target Neighborhood Hits	417	Shared Neighborhood Hits	46
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

JARD2_MOUSE
θ value	2.36792 (rank : 193)	NC score	0.016704 (rank : 199)
Query Neighborhood Hits	332	Target Neighborhood Hits	169	Shared Neighborhood Hits	21
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

LEG3_HUMAN
θ value	2.36792 (rank : 194)	NC score	0.014589 (rank : 221)
Query Neighborhood Hits	332	Target Neighborhood Hits	124	Shared Neighborhood Hits	23
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

PAK4_MOUSE
θ value	2.36792 (rank : 195)	NC score	-0.004355 (rank : 329)
Query Neighborhood Hits	332	Target Neighborhood Hits	1098	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PHAR3_HUMAN
θ value	2.36792 (rank : 196)	NC score	0.014737 (rank : 220)
Query Neighborhood Hits	332	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

RAI1_MOUSE
θ value	2.36792 (rank : 197)	NC score	0.021443 (rank : 177)
Query Neighborhood Hits	332	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SEN34_MOUSE
θ value	2.36792 (rank : 198)	NC score	0.022847 (rank : 170)
Query Neighborhood Hits	332	Target Neighborhood Hits	158	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

TCOF_HUMAN
θ value	2.36792 (rank : 199)	NC score	0.033677 (rank : 128)
Query Neighborhood Hits	332	Target Neighborhood Hits	543	Shared Neighborhood Hits	56
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TMPSD_HUMAN
θ value	2.36792 (rank : 200)	NC score	-0.000059 (rank : 310)
Query Neighborhood Hits	332	Target Neighborhood Hits	333	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TXLNB_HUMAN
θ value	2.36792 (rank : 201)	NC score	0.014999 (rank : 213)
Query Neighborhood Hits	332	Target Neighborhood Hits	912	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

YBOX2_MOUSE
θ value	2.36792 (rank : 202)	NC score	0.011006 (rank : 246)
Query Neighborhood Hits	332	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

CEND1_HUMAN
θ value	3.0926 (rank : 203)	NC score	0.002962 (rank : 296)
Query Neighborhood Hits	332	Target Neighborhood Hits	284	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CO6A1_MOUSE
θ value	3.0926 (rank : 204)	NC score	0.025219 (rank : 161)
Query Neighborhood Hits	332	Target Neighborhood Hits	241	Shared Neighborhood Hits	41
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO7A1_HUMAN
θ value	3.0926 (rank : 205)	NC score	0.023552 (rank : 168)
Query Neighborhood Hits	332	Target Neighborhood Hits	807	Shared Neighborhood Hits	69
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DCDC2_MOUSE
θ value	3.0926 (rank : 206)	NC score	0.020702 (rank : 181)
Query Neighborhood Hits	332	Target Neighborhood Hits	247	Shared Neighborhood Hits	40
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

DVL2_HUMAN
θ value	3.0926 (rank : 207)	NC score	0.005355 (rank : 283)
Query Neighborhood Hits	332	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

GP179_HUMAN
θ value	3.0926 (rank : 208)	NC score	0.026356 (rank : 157)
Query Neighborhood Hits	332	Target Neighborhood Hits	372	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

KLF15_HUMAN
θ value	3.0926 (rank : 209)	NC score	-0.005527 (rank : 332)
Query Neighborhood Hits	332	Target Neighborhood Hits	720	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIH9	Gene names	KLF15, KKLF
Domain Architecture
Description	Krueppel-like factor 15 (Kidney-enriched krueppel-like factor).

SIRT1_MOUSE
θ value	3.0926 (rank : 210)	NC score	0.008298 (rank : 259)
Query Neighborhood Hits	332	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

SMG5_HUMAN
θ value	3.0926 (rank : 211)	NC score	0.014812 (rank : 217)
Query Neighborhood Hits	332	Target Neighborhood Hits	180	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

SMRD3_HUMAN
θ value	3.0926 (rank : 212)	NC score	0.010776 (rank : 248)
Query Neighborhood Hits	332	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q6STE5, Q75MJ2, Q75MR8, Q92926, Q9BUH1	Gene names	SMARCD3, BAF60C
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C).

SP7_MOUSE
θ value	3.0926 (rank : 213)	NC score	-0.005140 (rank : 330)
Query Neighborhood Hits	332	Target Neighborhood Hits	756	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

TTC15_HUMAN
θ value	3.0926 (rank : 214)	NC score	0.021861 (rank : 175)
Query Neighborhood Hits	332	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

UBP42_HUMAN
θ value	3.0926 (rank : 215)	NC score	0.016608 (rank : 202)
Query Neighborhood Hits	332	Target Neighborhood Hits	445	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

ZGPAT_MOUSE
θ value	3.0926 (rank : 216)	NC score	0.011457 (rank : 241)
Query Neighborhood Hits	332	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

AIPL1_HUMAN
θ value	4.03905 (rank : 217)	NC score	0.008327 (rank : 258)
Query Neighborhood Hits	332	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

COCA1_HUMAN
θ value	4.03905 (rank : 218)	NC score	0.015518 (rank : 209)
Query Neighborhood Hits	332	Target Neighborhood Hits	458	Shared Neighborhood Hits	51
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COFA1_MOUSE
θ value	4.03905 (rank : 219)	NC score	0.025519 (rank : 159)
Query Neighborhood Hits	332	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CSPG5_MOUSE
θ value	4.03905 (rank : 220)	NC score	0.018431 (rank : 187)
Query Neighborhood Hits	332	Target Neighborhood Hits	211	Shared Neighborhood Hits	30
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

FYCO1_HUMAN
θ value	4.03905 (rank : 221)	NC score	-0.001562 (rank : 318)
Query Neighborhood Hits	332	Target Neighborhood Hits	1149	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

HHEX_MOUSE
θ value	4.03905 (rank : 222)	NC score	0.000177 (rank : 309)
Query Neighborhood Hits	332	Target Neighborhood Hits	350	Shared Neighborhood Hits	8
SwissProt Accessions	P43120	Gene names	Hhex, Prhx
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

JPH2_MOUSE
θ value	4.03905 (rank : 223)	NC score	0.015267 (rank : 211)
Query Neighborhood Hits	332	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LGR4_HUMAN
θ value	4.03905 (rank : 224)	NC score	-0.002632 (rank : 323)
Query Neighborhood Hits	332	Target Neighborhood Hits	481	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

NPBL_MOUSE
θ value	4.03905 (rank : 225)	NC score	0.044319 (rank : 109)
Query Neighborhood Hits	332	Target Neighborhood Hits	1041	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RYR1_HUMAN
θ value	4.03905 (rank : 226)	NC score	0.017263 (rank : 198)
Query Neighborhood Hits	332	Target Neighborhood Hits	303	Shared Neighborhood Hits	29
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

SMRD3_MOUSE
θ value	4.03905 (rank : 227)	NC score	0.010347 (rank : 250)
Query Neighborhood Hits	332	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P9Z1, Q921D3, Q9CX89, Q9DB99	Gene names	Smarcd3, Baf60c
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (mBAF60c).

SYNPO_HUMAN
θ value	4.03905 (rank : 228)	NC score	0.012584 (rank : 230)
Query Neighborhood Hits	332	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TARA_MOUSE
θ value	4.03905 (rank : 229)	NC score	0.023852 (rank : 166)
Query Neighborhood Hits	332	Target Neighborhood Hits	1133	Shared Neighborhood Hits	82
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

THAP3_HUMAN
θ value	4.03905 (rank : 230)	NC score	0.009634 (rank : 253)
Query Neighborhood Hits	332	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WTV1, Q569K1, Q5TH66, Q5TH67, Q8N8T6, Q9BSC7, Q9Y3H2, Q9Y3H3	Gene names	THAP3
Domain Architecture
Description	THAP domain-containing protein 3.

WNK2_HUMAN
θ value	4.03905 (rank : 231)	NC score	-0.001327 (rank : 316)
Query Neighborhood Hits	332	Target Neighborhood Hits	1407	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AATK_HUMAN
θ value	5.27518 (rank : 232)	NC score	-0.000117 (rank : 311)
Query Neighborhood Hits	332	Target Neighborhood Hits	1243	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AFF2_HUMAN
θ value	5.27518 (rank : 233)	NC score	0.012559 (rank : 231)
Query Neighborhood Hits	332	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

AMYP_HUMAN
θ value	5.27518 (rank : 234)	NC score	0.007761 (rank : 265)
Query Neighborhood Hits	332	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P04746, Q9UBH3	Gene names	AMY2A
Domain Architecture
Description	Pancreatic alpha-amylase precursor (EC 3.2.1.1) (PA) (1,4-alpha-D- glucan glucanohydrolase).

ANKY2_MOUSE
θ value	5.27518 (rank : 235)	NC score	0.004872 (rank : 285)
Query Neighborhood Hits	332	Target Neighborhood Hits	316	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

BAT2_MOUSE
θ value	5.27518 (rank : 236)	NC score	0.027523 (rank : 150)
Query Neighborhood Hits	332	Target Neighborhood Hits	947	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CABIN_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.027402 (rank : 151)
Query Neighborhood Hits	332	Target Neighborhood Hits	490	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CDN1C_MOUSE
θ value	5.27518 (rank : 238)	NC score	0.024065 (rank : 165)
Query Neighborhood Hits	332	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CENPB_MOUSE
θ value	5.27518 (rank : 239)	NC score	0.011558 (rank : 240)
Query Neighborhood Hits	332	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

CHD2_HUMAN
θ value	5.27518 (rank : 240)	NC score	0.020766 (rank : 180)
Query Neighborhood Hits	332	Target Neighborhood Hits	360	Shared Neighborhood Hits	44
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

COBA1_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.031018 (rank : 135)
Query Neighborhood Hits	332	Target Neighborhood Hits	491	Shared Neighborhood Hits	67
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COCA1_MOUSE
θ value	5.27518 (rank : 242)	NC score	0.015431 (rank : 210)
Query Neighborhood Hits	332	Target Neighborhood Hits	467	Shared Neighborhood Hits	50
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

DEDD2_HUMAN
θ value	5.27518 (rank : 243)	NC score	0.008694 (rank : 256)
Query Neighborhood Hits	332	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXF8, Q8NBR2, Q8NES1, Q8TAA8, Q96D35	Gene names	DEDD2, FLAME3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

DGKK_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.014391 (rank : 222)
Query Neighborhood Hits	332	Target Neighborhood Hits	378	Shared Neighborhood Hits	33
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DIDO1_HUMAN
θ value	5.27518 (rank : 245)	NC score	0.036790 (rank : 117)
Query Neighborhood Hits	332	Target Neighborhood Hits	960	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FBLN2_HUMAN
θ value	5.27518 (rank : 246)	NC score	-0.002559 (rank : 322)
Query Neighborhood Hits	332	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBX42_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.006837 (rank : 271)
Query Neighborhood Hits	332	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FBXW8_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.004100 (rank : 290)
Query Neighborhood Hits	332	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

GBP2_MOUSE
θ value	5.27518 (rank : 249)	NC score	0.004112 (rank : 289)
Query Neighborhood Hits	332	Target Neighborhood Hits	323	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

LBXCO_HUMAN
θ value	5.27518 (rank : 250)	NC score	0.011580 (rank : 239)
Query Neighborhood Hits	332	Target Neighborhood Hits	167	Shared Neighborhood Hits	23
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

LDB3_MOUSE
θ value	5.27518 (rank : 251)	NC score	0.006718 (rank : 272)
Query Neighborhood Hits	332	Target Neighborhood Hits	510	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LNK_HUMAN
θ value	5.27518 (rank : 252)	NC score	0.007576 (rank : 268)
Query Neighborhood Hits	332	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

NCKX1_HUMAN
θ value	5.27518 (rank : 253)	NC score	0.017563 (rank : 194)
Query Neighborhood Hits	332	Target Neighborhood Hits	223	Shared Neighborhood Hits	30
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

PABP2_MOUSE
θ value	5.27518 (rank : 254)	NC score	0.007641 (rank : 266)
Query Neighborhood Hits	332	Target Neighborhood Hits	214	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PRDM8_MOUSE
θ value	5.27518 (rank : 255)	NC score	0.007884 (rank : 264)
Query Neighborhood Hits	332	Target Neighborhood Hits	176	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BZ97	Gene names	Prdm8
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

REXO1_MOUSE
θ value	5.27518 (rank : 256)	NC score	0.011968 (rank : 234)
Query Neighborhood Hits	332	Target Neighborhood Hits	166	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

RFIP1_MOUSE
θ value	5.27518 (rank : 257)	NC score	0.011637 (rank : 238)
Query Neighborhood Hits	332	Target Neighborhood Hits	152	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SC24C_HUMAN
θ value	5.27518 (rank : 258)	NC score	0.014797 (rank : 218)
Query Neighborhood Hits	332	Target Neighborhood Hits	662	Shared Neighborhood Hits	59
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SPEG_HUMAN
θ value	5.27518 (rank : 259)	NC score	0.001667 (rank : 302)
Query Neighborhood Hits	332	Target Neighborhood Hits	1762	Shared Neighborhood Hits	84
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRRM2_HUMAN
θ value	5.27518 (rank : 260)	NC score	0.028232 (rank : 149)
Query Neighborhood Hits	332	Target Neighborhood Hits	1296	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

T240L_HUMAN
θ value	5.27518 (rank : 261)	NC score	0.006592 (rank : 273)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

TERF1_HUMAN
θ value	5.27518 (rank : 262)	NC score	0.012971 (rank : 227)
Query Neighborhood Hits	332	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	P54274, Q15553, Q93029	Gene names	TERF1, PIN2, TRF, TRF1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1).

TXLNA_HUMAN
θ value	5.27518 (rank : 263)	NC score	0.016611 (rank : 201)
Query Neighborhood Hits	332	Target Neighborhood Hits	982	Shared Neighborhood Hits	95
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ZN592_HUMAN
θ value	5.27518 (rank : 264)	NC score	-0.003808 (rank : 327)
Query Neighborhood Hits	332	Target Neighborhood Hits	762	Shared Neighborhood Hits	22
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

ZN646_HUMAN
θ value	5.27518 (rank : 265)	NC score	-0.006426 (rank : 336)
Query Neighborhood Hits	332	Target Neighborhood Hits	813	Shared Neighborhood Hits	22
SwissProt Accessions	O15015	Gene names	ZNF646, KIAA0296
Domain Architecture	No domain graphic available
Description	Zinc finger protein 646.

AATK_MOUSE
θ value	6.88961 (rank : 266)	NC score	-0.001727 (rank : 320)
Query Neighborhood Hits	332	Target Neighborhood Hits	942	Shared Neighborhood Hits	38
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

AKP8L_MOUSE
θ value	6.88961 (rank : 267)	NC score	0.011221 (rank : 242)
Query Neighborhood Hits	332	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

APXL_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.017804 (rank : 191)
Query Neighborhood Hits	332	Target Neighborhood Hits	553	Shared Neighborhood Hits	57
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BIN1_HUMAN
θ value	6.88961 (rank : 269)	NC score	0.015204 (rank : 212)
Query Neighborhood Hits	332	Target Neighborhood Hits	335	Shared Neighborhood Hits	33
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

DMP1_HUMAN
θ value	6.88961 (rank : 270)	NC score	0.031399 (rank : 134)
Query Neighborhood Hits	332	Target Neighborhood Hits	491	Shared Neighborhood Hits	40
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

FMN2_HUMAN
θ value	6.88961 (rank : 271)	NC score	0.019147 (rank : 185)
Query Neighborhood Hits	332	Target Neighborhood Hits	484	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GRIN1_HUMAN
θ value	6.88961 (rank : 272)	NC score	0.036227 (rank : 121)
Query Neighborhood Hits	332	Target Neighborhood Hits	681	Shared Neighborhood Hits	94
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HAND1_MOUSE
θ value	6.88961 (rank : 273)	NC score	0.002998 (rank : 294)
Query Neighborhood Hits	332	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

HUWE1_HUMAN
θ value	6.88961 (rank : 274)	NC score	0.005695 (rank : 280)
Query Neighborhood Hits	332	Target Neighborhood Hits	443	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HXA13_HUMAN
θ value	6.88961 (rank : 275)	NC score	0.000984 (rank : 306)
Query Neighborhood Hits	332	Target Neighborhood Hits	353	Shared Neighborhood Hits	13
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

HXD4_HUMAN
θ value	6.88961 (rank : 276)	NC score	0.000455 (rank : 308)
Query Neighborhood Hits	332	Target Neighborhood Hits	337	Shared Neighborhood Hits	13
SwissProt Accessions	P09016, Q96AU0	Gene names	HOXD4, HOX4B
Domain Architecture
Description	Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13).

KCNH2_MOUSE
θ value	6.88961 (rank : 277)	NC score	0.002241 (rank : 301)
Query Neighborhood Hits	332	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

LEO1_MOUSE
θ value	6.88961 (rank : 278)	NC score	0.041923 (rank : 112)
Query Neighborhood Hits	332	Target Neighborhood Hits	946	Shared Neighborhood Hits	65
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MINT_MOUSE
θ value	6.88961 (rank : 279)	NC score	0.028603 (rank : 146)
Query Neighborhood Hits	332	Target Neighborhood Hits	1514	Shared Neighborhood Hits	106
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL2_HUMAN
θ value	6.88961 (rank : 280)	NC score	0.016691 (rank : 200)
Query Neighborhood Hits	332	Target Neighborhood Hits	1788	Shared Neighborhood Hits	113
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYPC2_MOUSE
θ value	6.88961 (rank : 281)	NC score	0.005378 (rank : 282)
Query Neighborhood Hits	332	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NFL_HUMAN
θ value	6.88961 (rank : 282)	NC score	0.007577 (rank : 267)
Query Neighborhood Hits	332	Target Neighborhood Hits	666	Shared Neighborhood Hits	30
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

PR285_HUMAN
θ value	6.88961 (rank : 283)	NC score	0.005515 (rank : 281)
Query Neighborhood Hits	332	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

PRB4S_HUMAN
θ value	6.88961 (rank : 284)	NC score	0.028712 (rank : 145)
Query Neighborhood Hits	332	Target Neighborhood Hits	330	Shared Neighborhood Hits	45
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PVRL2_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.002379 (rank : 300)
Query Neighborhood Hits	332	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

RAI1_HUMAN
θ value	6.88961 (rank : 286)	NC score	0.020887 (rank : 179)
Query Neighborhood Hits	332	Target Neighborhood Hits	360	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RFIP1_HUMAN
θ value	6.88961 (rank : 287)	NC score	0.017892 (rank : 190)
Query Neighborhood Hits	332	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TEX2_MOUSE
θ value	6.88961 (rank : 288)	NC score	0.011770 (rank : 236)
Query Neighborhood Hits	332	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TOPB1_HUMAN
θ value	6.88961 (rank : 289)	NC score	0.005913 (rank : 278)
Query Neighborhood Hits	332	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

TTBK1_HUMAN
θ value	6.88961 (rank : 290)	NC score	-0.000281 (rank : 313)
Query Neighborhood Hits	332	Target Neighborhood Hits	1058	Shared Neighborhood Hits	47
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TTC16_HUMAN
θ value	6.88961 (rank : 291)	NC score	0.022219 (rank : 174)
Query Neighborhood Hits	332	Target Neighborhood Hits	417	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

U383_HUMAN
θ value	6.88961 (rank : 292)	NC score	0.007099 (rank : 269)
Query Neighborhood Hits	332	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYL2	Gene names	C4orf23
Domain Architecture	No domain graphic available
Description	Putative methyltransferase UPF0383 (EC 2.1.1.-).

UBP10_MOUSE
θ value	6.88961 (rank : 293)	NC score	0.007891 (rank : 263)
Query Neighborhood Hits	332	Target Neighborhood Hits	150	Shared Neighborhood Hits	16
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

VASP_HUMAN
θ value	6.88961 (rank : 294)	NC score	0.022706 (rank : 171)
Query Neighborhood Hits	332	Target Neighborhood Hits	201	Shared Neighborhood Hits	33
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

ZMYM3_HUMAN
θ value	6.88961 (rank : 295)	NC score	0.010002 (rank : 252)
Query Neighborhood Hits	332	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

ZN516_HUMAN
θ value	6.88961 (rank : 296)	NC score	-0.004262 (rank : 328)
Query Neighborhood Hits	332	Target Neighborhood Hits	854	Shared Neighborhood Hits	40
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

AP3B2_HUMAN
θ value	8.99809 (rank : 297)	NC score	0.005986 (rank : 276)
Query Neighborhood Hits	332	Target Neighborhood Hits	246	Shared Neighborhood Hits	24
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

BARX1_MOUSE
θ value	8.99809 (rank : 298)	NC score	-0.001387 (rank : 317)
Query Neighborhood Hits	332	Target Neighborhood Hits	324	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER42, O09066, P70159, Q9ERV2	Gene names	Barx1
Domain Architecture
Description	Homeobox protein BarH-like 1.

BCL7A_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.013195 (rank : 226)
Query Neighborhood Hits	332	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

CCD96_HUMAN
θ value	8.99809 (rank : 300)	NC score	0.010066 (rank : 251)
Query Neighborhood Hits	332	Target Neighborhood Hits	595	Shared Neighborhood Hits	44
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CO1A2_HUMAN
θ value	8.99809 (rank : 301)	NC score	0.031543 (rank : 133)
Query Neighborhood Hits	332	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO5A3_HUMAN
θ value	8.99809 (rank : 302)	NC score	0.028329 (rank : 148)
Query Neighborhood Hits	332	Target Neighborhood Hits	433	Shared Neighborhood Hits	57
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO6A1_HUMAN
θ value	8.99809 (rank : 303)	NC score	0.024763 (rank : 164)
Query Neighborhood Hits	332	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO9A3_HUMAN
θ value	8.99809 (rank : 304)	NC score	0.025962 (rank : 158)
Query Neighborhood Hits	332	Target Neighborhood Hits	361	Shared Neighborhood Hits	55
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CP053_HUMAN
θ value	8.99809 (rank : 305)	NC score	0.011083 (rank : 245)
Query Neighborhood Hits	332	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

CSKI1_HUMAN
θ value	8.99809 (rank : 306)	NC score	0.012241 (rank : 233)
Query Neighborhood Hits	332	Target Neighborhood Hits	997	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CUTL1_HUMAN
θ value	8.99809 (rank : 307)	NC score	0.002675 (rank : 298)
Query Neighborhood Hits	332	Target Neighborhood Hits	1574	Shared Neighborhood Hits	56
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DNL3_HUMAN
θ value	8.99809 (rank : 308)	NC score	0.004196 (rank : 288)
Query Neighborhood Hits	332	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DYNA_HUMAN
θ value	8.99809 (rank : 309)	NC score	0.002972 (rank : 295)
Query Neighborhood Hits	332	Target Neighborhood Hits	1194	Shared Neighborhood Hits	37
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	8.99809 (rank : 310)	NC score	0.004065 (rank : 291)
Query Neighborhood Hits	332	Target Neighborhood Hits	1084	Shared Neighborhood Hits	33
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

E41L1_HUMAN
θ value	8.99809 (rank : 311)	NC score	0.008034 (rank : 261)
Query Neighborhood Hits	332	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

EDN3_MOUSE
θ value	8.99809 (rank : 312)	NC score	0.011161 (rank : 243)
Query Neighborhood Hits	332	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P48299, Q543L0	Gene names	Edn3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

ERR1_HUMAN
θ value	8.99809 (rank : 313)	NC score	-0.000301 (rank : 314)
Query Neighborhood Hits	332	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

GBF1_HUMAN
θ value	8.99809 (rank : 314)	NC score	0.008022 (rank : 262)
Query Neighborhood Hits	332	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

GMIP_HUMAN
θ value	8.99809 (rank : 315)	NC score	0.001209 (rank : 304)
Query Neighborhood Hits	332	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

HRX_HUMAN
θ value	8.99809 (rank : 316)	NC score	0.014059 (rank : 223)
Query Neighborhood Hits	332	Target Neighborhood Hits	825	Shared Neighborhood Hits	56
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HXB4_HUMAN
θ value	8.99809 (rank : 317)	NC score	0.001349 (rank : 303)
Query Neighborhood Hits	332	Target Neighborhood Hits	376	Shared Neighborhood Hits	18
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

KLF14_HUMAN
θ value	8.99809 (rank : 318)	NC score	-0.006140 (rank : 334)
Query Neighborhood Hits	332	Target Neighborhood Hits	725	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

LRSM1_MOUSE
θ value	8.99809 (rank : 319)	NC score	-0.003697 (rank : 326)
Query Neighborhood Hits	332	Target Neighborhood Hits	874	Shared Neighborhood Hits	20
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

NFH_HUMAN
θ value	8.99809 (rank : 320)	NC score	0.020348 (rank : 182)
Query Neighborhood Hits	332	Target Neighborhood Hits	1242	Shared Neighborhood Hits	83
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PER1_HUMAN
θ value	8.99809 (rank : 321)	NC score	0.006086 (rank : 275)
Query Neighborhood Hits	332	Target Neighborhood Hits	215	Shared Neighborhood Hits	18
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

RGP2_HUMAN
θ value	8.99809 (rank : 322)	NC score	0.005947 (rank : 277)
Query Neighborhood Hits	332	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

RREB1_HUMAN
θ value	8.99809 (rank : 323)	NC score	-0.002999 (rank : 324)
Query Neighborhood Hits	332	Target Neighborhood Hits	879	Shared Neighborhood Hits	39
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SALL3_HUMAN
θ value	8.99809 (rank : 324)	NC score	-0.002363 (rank : 321)
Query Neighborhood Hits	332	Target Neighborhood Hits	1066	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SEN34_HUMAN
θ value	8.99809 (rank : 325)	NC score	0.012783 (rank : 228)
Query Neighborhood Hits	332	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BSV6, Q9BVT1, Q9H6H5	Gene names	TSEN34, LENG5, SEN34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (HsSen34) (Leukocyte receptor cluster member 5).

SH3BG_HUMAN
θ value	8.99809 (rank : 326)	NC score	0.013337 (rank : 224)
Query Neighborhood Hits	332	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	P55822, Q9BRB8	Gene names	SH3BGR
Domain Architecture
Description	SH3 domain-binding glutamic acid-rich protein (SH3BGR protein) (21- glutamic acid-rich protein) (21-GARP).

SIAL_MOUSE
θ value	8.99809 (rank : 327)	NC score	0.015765 (rank : 207)
Query Neighborhood Hits	332	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q61711, Q61363	Gene names	Ibsp
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

SP7_HUMAN
θ value	8.99809 (rank : 328)	NC score	-0.005343 (rank : 331)
Query Neighborhood Hits	332	Target Neighborhood Hits	734	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

SREC2_HUMAN
θ value	8.99809 (rank : 329)	NC score	0.000556 (rank : 307)
Query Neighborhood Hits	332	Target Neighborhood Hits	645	Shared Neighborhood Hits	25
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TCF20_MOUSE
θ value	8.99809 (rank : 330)	NC score	0.014893 (rank : 216)
Query Neighborhood Hits	332	Target Neighborhood Hits	396	Shared Neighborhood Hits	44
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

WDR79_HUMAN
θ value	8.99809 (rank : 331)	NC score	0.003495 (rank : 293)
Query Neighborhood Hits	332	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

ZHX1_MOUSE
θ value	8.99809 (rank : 332)	NC score	0.001205 (rank : 305)
Query Neighborhood Hits	332	Target Neighborhood Hits	334	Shared Neighborhood Hits	11
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

CC026_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.136652 (rank : 89)
Query Neighborhood Hits	332	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.109797 (rank : 91)
Query Neighborhood Hits	332	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

OGFR_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.059574 (rank : 100)
Query Neighborhood Hits	332	Target Neighborhood Hits	584	Shared Neighborhood Hits	92
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SMAL1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.068698 (rank : 96)
Query Neighborhood Hits	332	Target Neighborhood Hits	174	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

Hits sorted by NC score

DDX51_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	332	Target Neighborhood Hits	332	Shared Neighborhood Hits	332
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX51_MOUSE
NC score	0.980622 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	332	Target Neighborhood Hits	130	Shared Neighborhood Hits	99
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX27_MOUSE
NC score	0.936834 (rank : 3)	θ value	2.58187e-47 (rank : 3)
Query Neighborhood Hits	332	Target Neighborhood Hits	174	Shared Neighborhood Hits	90
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX47_MOUSE
NC score	0.934821 (rank : 4)	θ value	1.79215e-40 (rank : 5)
Query Neighborhood Hits	332	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.934183 (rank : 5)	θ value	1.98146e-39 (rank : 7)
Query Neighborhood Hits	332	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX27_HUMAN
NC score	0.934128 (rank : 6)	θ value	5.95217e-44 (rank : 4)
Query Neighborhood Hits	332	Target Neighborhood Hits	197	Shared Neighborhood Hits	88
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX49_MOUSE
NC score	0.933848 (rank : 7)	θ value	1.51715e-39 (rank : 6)
Query Neighborhood Hits	332	Target Neighborhood Hits	119	Shared Neighborhood Hits	90
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_HUMAN
NC score	0.931194 (rank : 8)	θ value	5.76516e-39 (rank : 8)
Query Neighborhood Hits	332	Target Neighborhood Hits	223	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX18_MOUSE
NC score	0.925928 (rank : 9)	θ value	7.29293e-34 (rank : 11)
Query Neighborhood Hits	332	Target Neighborhood Hits	115	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX31_HUMAN
NC score	0.924953 (rank : 10)	θ value	4.14116e-29 (rank : 17)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX18_HUMAN
NC score	0.924453 (rank : 11)	θ value	2.34606e-32 (rank : 14)
Query Neighborhood Hits	332	Target Neighborhood Hits	124	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX52_MOUSE
NC score	0.924430 (rank : 12)	θ value	6.17384e-33 (rank : 13)
Query Neighborhood Hits	332	Target Neighborhood Hits	101	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_HUMAN
NC score	0.924370 (rank : 13)	θ value	4.72714e-33 (rank : 12)
Query Neighborhood Hits	332	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX55_MOUSE
NC score	0.923523 (rank : 14)	θ value	3.74554e-30 (rank : 16)
Query Neighborhood Hits	332	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.922563 (rank : 15)	θ value	9.8567e-31 (rank : 15)
Query Neighborhood Hits	332	Target Neighborhood Hits	122	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX10_HUMAN
NC score	0.920623 (rank : 16)	θ value	1.9192e-34 (rank : 9)
Query Neighborhood Hits	332	Target Neighborhood Hits	210	Shared Neighborhood Hits	87
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
NC score	0.920169 (rank : 17)	θ value	3.27365e-34 (rank : 10)
Query Neighborhood Hits	332	Target Neighborhood Hits	233	Shared Neighborhood Hits	88
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX56_HUMAN
NC score	0.918273 (rank : 18)	θ value	3.50572e-28 (rank : 23)
Query Neighborhood Hits	332	Target Neighborhood Hits	77	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX56_MOUSE
NC score	0.918144 (rank : 19)	θ value	5.40856e-29 (rank : 21)
Query Neighborhood Hits	332	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX41_HUMAN
NC score	0.914494 (rank : 20)	θ value	1.02001e-27 (rank : 27)
Query Neighborhood Hits	332	Target Neighborhood Hits	111	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.914111 (rank : 21)	θ value	1.33217e-27 (rank : 28)
Query Neighborhood Hits	332	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX54_MOUSE
NC score	0.913958 (rank : 22)	θ value	5.59698e-26 (rank : 32)
Query Neighborhood Hits	332	Target Neighborhood Hits	124	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX28_MOUSE
NC score	0.911862 (rank : 23)	θ value	3.75424e-22 (rank : 37)
Query Neighborhood Hits	332	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX54_HUMAN
NC score	0.911196 (rank : 24)	θ value	3.28125e-26 (rank : 31)
Query Neighborhood Hits	332	Target Neighborhood Hits	170	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX4_MOUSE
NC score	0.909256 (rank : 25)	θ value	5.06226e-27 (rank : 30)
Query Neighborhood Hits	332	Target Neighborhood Hits	100	Shared Neighborhood Hits	90
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX4_HUMAN
NC score	0.908647 (rank : 26)	θ value	1.73987e-27 (rank : 29)
Query Neighborhood Hits	332	Target Neighborhood Hits	123	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX28_HUMAN
NC score	0.907942 (rank : 27)	θ value	1.86321e-21 (rank : 41)
Query Neighborhood Hits	332	Target Neighborhood Hits	103	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX6_HUMAN
NC score	0.907387 (rank : 28)	θ value	3.51386e-20 (rank : 56)
Query Neighborhood Hits	332	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX50_MOUSE
NC score	0.907365 (rank : 29)	θ value	4.57862e-28 (rank : 24)
Query Neighborhood Hits	332	Target Neighborhood Hits	137	Shared Neighborhood Hits	94
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX6_MOUSE
NC score	0.907267 (rank : 30)	θ value	3.51386e-20 (rank : 57)
Query Neighborhood Hits	332	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX50_HUMAN
NC score	0.907235 (rank : 31)	θ value	7.80994e-28 (rank : 26)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX43_HUMAN
NC score	0.905760 (rank : 32)	θ value	4.01107e-24 (rank : 35)
Query Neighborhood Hits	332	Target Neighborhood Hits	120	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX17_MOUSE
NC score	0.902036 (rank : 33)	θ value	3.62785e-25 (rank : 34)
Query Neighborhood Hits	332	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.901882 (rank : 34)	θ value	3.62785e-25 (rank : 33)
Query Neighborhood Hits	332	Target Neighborhood Hits	104	Shared Neighborhood Hits	87
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX24_MOUSE
NC score	0.899593 (rank : 35)	θ value	1.86321e-21 (rank : 40)
Query Neighborhood Hits	332	Target Neighborhood Hits	147	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX39_HUMAN
NC score	0.899005 (rank : 36)	θ value	1.86321e-21 (rank : 42)
Query Neighborhood Hits	332	Target Neighborhood Hits	94	Shared Neighborhood Hits	87
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX24_HUMAN
NC score	0.897591 (rank : 37)	θ value	1.86321e-21 (rank : 39)
Query Neighborhood Hits	332	Target Neighborhood Hits	190	Shared Neighborhood Hits	98
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX21_HUMAN
NC score	0.897213 (rank : 38)	θ value	5.97985e-28 (rank : 25)
Query Neighborhood Hits	332	Target Neighborhood Hits	308	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX39_MOUSE
NC score	0.896826 (rank : 39)	θ value	4.58923e-20 (rank : 58)
Query Neighborhood Hits	332	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

UAP56_HUMAN
NC score	0.895868 (rank : 40)	θ value	2.69047e-20 (rank : 54)
Query Neighborhood Hits	332	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
NC score	0.895842 (rank : 41)	θ value	2.69047e-20 (rank : 55)
Query Neighborhood Hits	332	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX46_HUMAN
NC score	0.895560 (rank : 42)	θ value	4.14116e-29 (rank : 18)
Query Neighborhood Hits	332	Target Neighborhood Hits	357	Shared Neighborhood Hits	109
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX21_MOUSE
NC score	0.895114 (rank : 43)	θ value	5.40856e-29 (rank : 20)
Query Neighborhood Hits	332	Target Neighborhood Hits	350	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

IF4A1_HUMAN
NC score	0.894625 (rank : 44)	θ value	1.2077e-20 (rank : 49)
Query Neighborhood Hits	332	Target Neighborhood Hits	106	Shared Neighborhood Hits	88
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.894625 (rank : 45)	θ value	1.2077e-20 (rank : 50)
Query Neighborhood Hits	332	Target Neighborhood Hits	106	Shared Neighborhood Hits	88
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
NC score	0.894381 (rank : 46)	θ value	2.43343e-21 (rank : 44)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.894381 (rank : 47)	θ value	2.43343e-21 (rank : 45)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX46_MOUSE
NC score	0.893161 (rank : 48)	θ value	4.14116e-29 (rank : 19)
Query Neighborhood Hits	332	Target Neighborhood Hits	358	Shared Neighborhood Hits	107
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

PL10_MOUSE
NC score	0.891418 (rank : 49)	θ value	3.75424e-22 (rank : 38)
Query Neighborhood Hits	332	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
NC score	0.891408 (rank : 50)	θ value	1.6852e-22 (rank : 36)
Query Neighborhood Hits	332	Target Neighborhood Hits	122	Shared Neighborhood Hits	88
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_MOUSE
NC score	0.891371 (rank : 51)	θ value	9.24701e-21 (rank : 48)
Query Neighborhood Hits	332	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX48_HUMAN
NC score	0.890544 (rank : 52)	θ value	7.84624e-12 (rank : 66)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX3X_MOUSE
NC score	0.890275 (rank : 53)	θ value	1.86321e-21 (rank : 43)
Query Neighborhood Hits	332	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX48_MOUSE
NC score	0.890262 (rank : 54)	θ value	7.84624e-12 (rank : 67)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX3Y_HUMAN
NC score	0.888805 (rank : 55)	θ value	9.24701e-21 (rank : 47)
Query Neighborhood Hits	332	Target Neighborhood Hits	121	Shared Neighborhood Hits	88
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX5_HUMAN
NC score	0.887985 (rank : 56)	θ value	2.88119e-14 (rank : 62)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX5_MOUSE
NC score	0.887864 (rank : 57)	θ value	2.88119e-14 (rank : 63)
Query Neighborhood Hits	332	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX53_HUMAN
NC score	0.887574 (rank : 58)	θ value	2.28291e-11 (rank : 68)
Query Neighborhood Hits	332	Target Neighborhood Hits	124	Shared Neighborhood Hits	84
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX23_HUMAN
NC score	0.885936 (rank : 59)	θ value	2.05525e-28 (rank : 22)
Query Neighborhood Hits	332	Target Neighborhood Hits	486	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX20_HUMAN
NC score	0.882423 (rank : 60)	θ value	5.60996e-18 (rank : 61)
Query Neighborhood Hits	332	Target Neighborhood Hits	121	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX25_HUMAN
NC score	0.882323 (rank : 61)	θ value	5.99374e-20 (rank : 59)
Query Neighborhood Hits	332	Target Neighborhood Hits	93	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_MOUSE
NC score	0.882144 (rank : 62)	θ value	2.06002e-20 (rank : 52)
Query Neighborhood Hits	332	Target Neighborhood Hits	98	Shared Neighborhood Hits	85
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DD19A_HUMAN
NC score	0.881574 (rank : 63)	θ value	7.0802e-21 (rank : 46)
Query Neighborhood Hits	332	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX20_MOUSE
NC score	0.881474 (rank : 64)	θ value	6.62687e-19 (rank : 60)
Query Neighborhood Hits	332	Target Neighborhood Hits	177	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DD19A_MOUSE
NC score	0.880999 (rank : 65)	θ value	1.5773e-20 (rank : 51)
Query Neighborhood Hits	332	Target Neighborhood Hits	105	Shared Neighborhood Hits	86
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
NC score	0.880571 (rank : 66)	θ value	2.69047e-20 (rank : 53)
Query Neighborhood Hits	332	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DDX1_MOUSE
NC score	0.837418 (rank : 67)	θ value	7.84624e-12 (rank : 65)
Query Neighborhood Hits	332	Target Neighborhood Hits	112	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.836050 (rank : 68)	θ value	7.84624e-12 (rank : 64)
Query Neighborhood Hits	332	Target Neighborhood Hits	110	Shared Neighborhood Hits	84
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.536650 (rank : 69)	θ value	1.09739e-05 (rank : 69)
Query Neighborhood Hits	332	Target Neighborhood Hits	177	Shared Neighborhood Hits	98
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.507098 (rank : 70)	θ value	0.00509761 (rank : 78)
Query Neighborhood Hits	332	Target Neighborhood Hits	206	Shared Neighborhood Hits	93
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.461905 (rank : 71)	θ value	0.0563607 (rank : 94)
Query Neighborhood Hits	332	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

RECQ5_HUMAN
NC score	0.459950 (rank : 72)	θ value	0.000270298 (rank : 75)
Query Neighborhood Hits	332	Target Neighborhood Hits	390	Shared Neighborhood Hits	128
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

FANCM_HUMAN
NC score	0.449193 (rank : 73)	θ value	0.000158464 (rank : 73)
Query Neighborhood Hits	332	Target Neighborhood Hits	210	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

BLM_HUMAN
NC score	0.449148 (rank : 74)	θ value	0.0563607 (rank : 93)
Query Neighborhood Hits	332	Target Neighborhood Hits	148	Shared Neighborhood Hits	76
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

FANCM_MOUSE
NC score	0.448608 (rank : 75)	θ value	1.87187e-05 (rank : 70)
Query Neighborhood Hits	332	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

WRN_HUMAN
NC score	0.446955 (rank : 76)	θ value	0.00509761 (rank : 79)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	81
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ1_MOUSE
NC score	0.413366 (rank : 77)	θ value	0.0252991 (rank : 88)
Query Neighborhood Hits	332	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_HUMAN
NC score	0.412557 (rank : 78)	θ value	0.0431538 (rank : 92)
Query Neighborhood Hits	332	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

WRN_MOUSE
NC score	0.411891 (rank : 79)	θ value	0.0113563 (rank : 85)
Query Neighborhood Hits	332	Target Neighborhood Hits	295	Shared Neighborhood Hits	86
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

DICER_MOUSE
NC score	0.409479 (rank : 80)	θ value	0.00509761 (rank : 77)
Query Neighborhood Hits	332	Target Neighborhood Hits	140	Shared Neighborhood Hits	85
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.408953 (rank : 81)	θ value	0.00665767 (rank : 80)
Query Neighborhood Hits	332	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

LGP2_MOUSE
NC score	0.349288 (rank : 82)	θ value	0.00869519 (rank : 82)
Query Neighborhood Hits	332	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

LGP2_HUMAN
NC score	0.347145 (rank : 83)	θ value	0.000121331 (rank : 71)
Query Neighborhood Hits	332	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_HUMAN
NC score	0.340746 (rank : 84)	θ value	0.0330416 (rank : 90)
Query Neighborhood Hits	332	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

IFIH1_MOUSE
NC score	0.326096 (rank : 85)	θ value	0.365318 (rank : 119)
Query Neighborhood Hits	332	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX58_MOUSE
NC score	0.234415 (rank : 86)	θ value	0.0736092 (rank : 98)
Query Neighborhood Hits	332	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.194360 (rank : 87)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	332	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

U520_HUMAN
NC score	0.175661 (rank : 88)	θ value	0.0961366 (rank : 103)
Query Neighborhood Hits	332	Target Neighborhood Hits	88	Shared Neighborhood Hits	48
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CC026_HUMAN
NC score	0.136652 (rank : 89)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	332	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

HELC1_HUMAN
NC score	0.133322 (rank : 90)	θ value	0.163984 (rank : 108)
Query Neighborhood Hits	332	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

CC026_MOUSE
NC score	0.109797 (rank : 91)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	332	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

TMAP1_HUMAN
NC score	0.082430 (rank : 92)	θ value	0.0736092 (rank : 101)
Query Neighborhood Hits	332	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

NEUM_HUMAN
NC score	0.074106 (rank : 93)	θ value	0.00869519 (rank : 83)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
NC score	0.071812 (rank : 94)	θ value	0.00869519 (rank : 84)
Query Neighborhood Hits	332	Target Neighborhood Hits	149	Shared Neighborhood Hits	27
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

BASP_HUMAN
NC score	0.069865 (rank : 95)	θ value	0.0736092 (rank : 97)
Query Neighborhood Hits	332	Target Neighborhood Hits	321	Shared Neighborhood Hits	58
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SMAL1_HUMAN
NC score	0.068698 (rank : 96)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	332	Target Neighborhood Hits	174	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

MARCS_MOUSE
NC score	0.064925 (rank : 97)	θ value	0.0736092 (rank : 99)
Query Neighborhood Hits	332	Target Neighborhood Hits	227	Shared Neighborhood Hits	48
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

BASP_MOUSE
NC score	0.061396 (rank : 98)	θ value	0.163984 (rank : 105)
Query Neighborhood Hits	332	Target Neighborhood Hits	260	Shared Neighborhood Hits	46
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

IWS1_MOUSE
NC score	0.059832 (rank : 99)	θ value	0.0563607 (rank : 95)
Query Neighborhood Hits	332	Target Neighborhood Hits	1258	Shared Neighborhood Hits	115
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

OGFR_MOUSE
NC score	0.059574 (rank : 100)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	332	Target Neighborhood Hits	584	Shared Neighborhood Hits	92
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OGFR_HUMAN
NC score	0.056796 (rank : 101)	θ value	0.00665767 (rank : 81)
Query Neighborhood Hits	332	Target Neighborhood Hits	1582	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

IWS1_HUMAN
NC score	0.056645 (rank : 102)	θ value	1.06291 (rank : 146)
Query Neighborhood Hits	332	Target Neighborhood Hits	1241	Shared Neighborhood Hits	106
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MARCS_HUMAN
NC score	0.051301 (rank : 103)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	332	Target Neighborhood Hits	204	Shared Neighborhood Hits	36
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

AKA12_HUMAN
NC score	0.048161 (rank : 104)	θ value	0.365318 (rank : 116)
Query Neighborhood Hits	332	Target Neighborhood Hits	825	Shared Neighborhood Hits	75
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

NFH_MOUSE
NC score	0.047592 (rank : 105)	θ value	0.000602161 (rank : 76)
Query Neighborhood Hits	332	Target Neighborhood Hits	2247	Shared Neighborhood Hits	170
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CMGA_HUMAN
NC score	0.047562 (rank : 106)	θ value	0.813845 (rank : 133)
Query Neighborhood Hits	332	Target Neighborhood Hits	238	Shared Neighborhood Hits	33
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

CN155_HUMAN
NC score	0.047357 (rank : 107)	θ value	0.163984 (rank : 106)
Query Neighborhood Hits	332	Target Neighborhood Hits	385	Shared Neighborhood Hits	42
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CLIC6_HUMAN
NC score	0.046166 (rank : 108)	θ value	0.0148317 (rank : 86)
Query Neighborhood Hits	332	Target Neighborhood Hits	289	Shared Neighborhood Hits	73
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

NPBL_MOUSE
NC score	0.044319 (rank : 109)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	332	Target Neighborhood Hits	1041	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TMAP1_MOUSE
NC score	0.044293 (rank : 110)	θ value	1.81305 (rank : 181)
Query Neighborhood Hits	332	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CZH7, Q8C6F8	Gene names	Tmap1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

ZN385_HUMAN
NC score	0.042788 (rank : 111)	θ value	0.0252991 (rank : 89)
Query Neighborhood Hits	332	Target Neighborhood Hits	614	Shared Neighborhood Hits	78
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

LEO1_MOUSE
NC score	0.041923 (rank : 112)	θ value	6.88961 (rank : 278)
Query Neighborhood Hits	332	Target Neighborhood Hits	946	Shared Neighborhood Hits	65
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

ASXL1_HUMAN
NC score	0.041714 (rank : 113)	θ value	0.0193708 (rank : 87)
Query Neighborhood Hits	332	Target Neighborhood Hits	260	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

RP1L1_HUMAN
NC score	0.041152 (rank : 114)	θ value	1.38821 (rank : 162)
Query Neighborhood Hits	332	Target Neighborhood Hits	1072	Shared Neighborhood Hits	127
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CTDP1_HUMAN
NC score	0.040917 (rank : 115)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	332	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

IF39_MOUSE
NC score	0.037096 (rank : 116)	θ value	0.279714 (rank : 114)
Query Neighborhood Hits	332	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

DIDO1_HUMAN
NC score	0.036790 (rank : 117)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	332	Target Neighborhood Hits	960	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CO1A1_MOUSE
NC score	0.036741 (rank : 118)	θ value	0.813845 (rank : 134)
Query Neighborhood Hits	332	Target Neighborhood Hits	457	Shared Neighborhood Hits	66
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SRCA_HUMAN
NC score	0.036467 (rank : 119)	θ value	0.0736092 (rank : 100)
Query Neighborhood Hits	332	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRRM2_MOUSE
NC score	0.036418 (rank : 120)	θ value	1.81305 (rank : 180)
Query Neighborhood Hits	332	Target Neighborhood Hits	1470	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

GRIN1_HUMAN
NC score	0.036227 (rank : 121)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	332	Target Neighborhood Hits	681	Shared Neighborhood Hits	94
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

CO3A1_MOUSE
NC score	0.035731 (rank : 122)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	332	Target Neighborhood Hits	466	Shared Neighborhood Hits	59
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

IF39_HUMAN
NC score	0.035725 (rank : 123)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	332	Target Neighborhood Hits	187	Shared Neighborhood Hits	21
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

CO3A1_HUMAN
NC score	0.035501 (rank : 124)	θ value	1.81305 (rank : 166)
Query Neighborhood Hits	332	Target Neighborhood Hits	452	Shared Neighborhood Hits	62
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO1A1_HUMAN
NC score	0.035275 (rank : 125)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	332	Target Neighborhood Hits	475	Shared Neighborhood Hits	62
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CTDP1_MOUSE
NC score	0.034181 (rank : 126)	θ value	0.47712 (rank : 121)
Query Neighborhood Hits	332	Target Neighborhood Hits	146	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

PRRT3_HUMAN
NC score	0.033807 (rank : 127)	θ value	1.81305 (rank : 178)
Query Neighborhood Hits	332	Target Neighborhood Hits	998	Shared Neighborhood Hits	102
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TCOF_HUMAN
NC score	0.033677 (rank : 128)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	332	Target Neighborhood Hits	543	Shared Neighborhood Hits	56
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CO2A1_HUMAN
NC score	0.033555 (rank : 129)	θ value	1.81305 (rank : 165)
Query Neighborhood Hits	332	Target Neighborhood Hits	486	Shared Neighborhood Hits	61
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

COBA1_MOUSE
NC score	0.033288 (rank : 130)	θ value	0.163984 (rank : 107)
Query Neighborhood Hits	332	Target Neighborhood Hits	487	Shared Neighborhood Hits	63
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

TAF4_HUMAN
NC score	0.032861 (rank : 131)	θ value	0.62314 (rank : 131)
Query Neighborhood Hits	332	Target Neighborhood Hits	687	Shared Neighborhood Hits	51
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CO2A1_MOUSE
NC score	0.031691 (rank : 132)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	332	Target Neighborhood Hits	483	Shared Neighborhood Hits	59
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO1A2_HUMAN
NC score	0.031543 (rank : 133)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	332	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

DMP1_HUMAN
NC score	0.031399 (rank : 134)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	332	Target Neighborhood Hits	491	Shared Neighborhood Hits	40
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

COBA1_HUMAN
NC score	0.031018 (rank : 135)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	332	Target Neighborhood Hits	491	Shared Neighborhood Hits	67
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

ASXL1_MOUSE
NC score	0.030961 (rank : 136)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	332	Target Neighborhood Hits	182	Shared Neighborhood Hits	20
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

PTMS_HUMAN
NC score	0.030436 (rank : 137)	θ value	1.81305 (rank : 179)
Query Neighborhood Hits	332	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

SON_HUMAN
NC score	0.030361 (rank : 138)	θ value	0.0563607 (rank : 96)
Query Neighborhood Hits	332	Target Neighborhood Hits	1568	Shared Neighborhood Hits	106
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

COBA2_MOUSE
NC score	0.030218 (rank : 139)	θ value	0.813845 (rank : 135)
Query Neighborhood Hits	332	Target Neighborhood Hits	501	Shared Neighborhood Hits	63
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

NHS_HUMAN
NC score	0.029701 (rank : 140)	θ value	1.06291 (rank : 148)
Query Neighborhood Hits	332	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

PWWP2_HUMAN
NC score	0.029501 (rank : 141)	θ value	0.365318 (rank : 120)
Query Neighborhood Hits	332	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

SH3BG_MOUSE
NC score	0.029465 (rank : 142)	θ value	0.163984 (rank : 111)
Query Neighborhood Hits	332	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUZ7	Gene names	Sh3bgr
Domain Architecture
Description	SH3 domain-binding glutamic acid-rich protein (SH3BGR protein).

RGS3_HUMAN
NC score	0.029145 (rank : 143)	θ value	0.163984 (rank : 109)
Query Neighborhood Hits	332	Target Neighborhood Hits	1375	Shared Neighborhood Hits	129
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

DNMT1_HUMAN
NC score	0.028879 (rank : 144)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	332	Target Neighborhood Hits	401	Shared Neighborhood Hits	36
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

PRB4S_HUMAN
NC score	0.028712 (rank : 145)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	332	Target Neighborhood Hits	330	Shared Neighborhood Hits	45
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

MINT_MOUSE
NC score	0.028603 (rank : 146)	θ value	6.88961 (rank : 279)
Query Neighborhood Hits	332	Target Neighborhood Hits	1514	Shared Neighborhood Hits	106
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

COAA1_MOUSE
NC score	0.028451 (rank : 147)	θ value	0.365318 (rank : 117)
Query Neighborhood Hits	332	Target Neighborhood Hits	286	Shared Neighborhood Hits	40
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CO5A3_HUMAN
NC score	0.028329 (rank : 148)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	332	Target Neighborhood Hits	433	Shared Neighborhood Hits	57
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

SRRM2_HUMAN
NC score	0.028232 (rank : 149)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	332	Target Neighborhood Hits	1296	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BAT2_MOUSE
NC score	0.027523 (rank : 150)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	332	Target Neighborhood Hits	947	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CABIN_HUMAN
NC score	0.027402 (rank : 151)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	332	Target Neighborhood Hits	490	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

COAA1_HUMAN
NC score	0.027313 (rank : 152)	θ value	1.81305 (rank : 167)
Query Neighborhood Hits	332	Target Neighborhood Hits	316	Shared Neighborhood Hits	51
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

DMP1_MOUSE
NC score	0.027243 (rank : 153)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	332	Target Neighborhood Hits	498	Shared Neighborhood Hits	45
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

INAR2_MOUSE
NC score	0.026708 (rank : 154)	θ value	0.279714 (rank : 115)
Query Neighborhood Hits	332	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O35664, O35238, O35663, O35983	Gene names	Ifnar2
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor beta chain precursor (IFN-alpha-REC) (Type I interferon receptor) (IFN-R) (Interferon alpha/beta receptor 2).

COIA1_MOUSE
NC score	0.026562 (rank : 155)	θ value	1.81305 (rank : 168)
Query Neighborhood Hits	332	Target Neighborhood Hits	481	Shared Neighborhood Hits	59
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CO4A4_HUMAN
NC score	0.026400 (rank : 156)	θ value	1.38821 (rank : 153)
Query Neighborhood Hits	332	Target Neighborhood Hits	440	Shared Neighborhood Hits	57
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

GP179_HUMAN
NC score	0.026356 (rank : 157)	θ value	3.0926 (rank : 208)
Query Neighborhood Hits	332	Target Neighborhood Hits	372	Shared Neighborhood Hits	49
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

CO9A3_HUMAN
NC score	0.025962 (rank : 158)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	332	Target Neighborhood Hits	361	Shared Neighborhood Hits	55
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COFA1_MOUSE
NC score	0.025519 (rank : 159)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	332	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

ZN326_MOUSE
NC score	0.025446 (rank : 160)	θ value	0.47712 (rank : 126)
Query Neighborhood Hits	332	Target Neighborhood Hits	117	Shared Neighborhood Hits	16
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

CO6A1_MOUSE
NC score	0.025219 (rank : 161)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	332	Target Neighborhood Hits	241	Shared Neighborhood Hits	41
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

GNAS1_HUMAN
NC score	0.024898 (rank : 162)	θ value	0.000270298 (rank : 74)
Query Neighborhood Hits	332	Target Neighborhood Hits	278	Shared Neighborhood Hits	41
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

FMN1B_MOUSE
NC score	0.024860 (rank : 163)	θ value	1.06291 (rank : 143)
Query Neighborhood Hits	332	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

CO6A1_HUMAN
NC score	0.024763 (rank : 164)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	332	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CDN1C_MOUSE
NC score	0.024065 (rank : 165)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	332	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

TARA_MOUSE
NC score	0.023852 (rank : 166)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	332	Target Neighborhood Hits	1133	Shared Neighborhood Hits	82
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TULP1_MOUSE
NC score	0.023588 (rank : 167)	θ value	0.163984 (rank : 112)
Query Neighborhood Hits	332	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

CO7A1_HUMAN
NC score	0.023552 (rank : 168)	θ value	3.0926 (rank : 205)
Query Neighborhood Hits	332	Target Neighborhood Hits	807	Shared Neighborhood Hits	69
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CLIC6_MOUSE
NC score	0.023486 (rank : 169)	θ value	1.38821 (rank : 152)
Query Neighborhood Hits	332	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

SEN34_MOUSE
NC score	0.022847 (rank : 170)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	332	Target Neighborhood Hits	158	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

VASP_HUMAN
NC score	0.022706 (rank : 171)	θ value	6.88961 (rank : 294)
Query Neighborhood Hits	332	Target Neighborhood Hits	201	Shared Neighborhood Hits	33
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

BSCL2_HUMAN
NC score	0.022544 (rank : 172)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	332	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

GNAS1_MOUSE
NC score	0.022321 (rank : 173)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	332	Target Neighborhood Hits	651	Shared Neighborhood Hits	65
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

TTC16_HUMAN
NC score	0.022219 (rank : 174)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	332	Target Neighborhood Hits	417	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TTC15_HUMAN
NC score	0.021861 (rank : 175)	θ value	3.0926 (rank : 214)
Query Neighborhood Hits	332	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

DMRT2_HUMAN
NC score	0.021459 (rank : 176)	θ value	1.06291 (rank : 141)
Query Neighborhood Hits	332	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5R5	Gene names	DMRT2, DSXL2
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2).

RAI1_MOUSE
NC score	0.021443 (rank : 177)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	332	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CSKI2_HUMAN
NC score	0.021097 (rank : 178)	θ value	0.000158464 (rank : 72)
Query Neighborhood Hits	332	Target Neighborhood Hits	747	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

RAI1_HUMAN
NC score	0.020887 (rank : 179)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	332	Target Neighborhood Hits	360	Shared Neighborhood Hits	50
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CHD2_HUMAN
NC score	0.020766 (rank : 180)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	332	Target Neighborhood Hits	360	Shared Neighborhood Hits	44
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

DCDC2_MOUSE
NC score	0.020702 (rank : 181)	θ value	3.0926 (rank : 206)
Query Neighborhood Hits	332	Target Neighborhood Hits	247	Shared Neighborhood Hits	40
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

NFH_HUMAN
NC score	0.020348 (rank : 182)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	332	Target Neighborhood Hits	1242	Shared Neighborhood Hits	83
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

IF4B_HUMAN
NC score	0.019337 (rank : 183)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	332	Target Neighborhood Hits	417	Shared Neighborhood Hits	46
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

ENAH_MOUSE
NC score	0.019174 (rank : 184)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	332	Target Neighborhood Hits	919	Shared Neighborhood Hits	51
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FMN2_HUMAN
NC score	0.019147 (rank : 185)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	332	Target Neighborhood Hits	484	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

BCL7A_MOUSE
NC score	0.018487 (rank : 186)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	332	Target Neighborhood Hits	74	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

CSPG5_MOUSE
NC score	0.018431 (rank : 187)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	332	Target Neighborhood Hits	211	Shared Neighborhood Hits	30
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

COPT2_HUMAN
NC score	0.018375 (rank : 188)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	332	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O15432	Gene names	SLC31A2, COPT2, CTR2
Domain Architecture
Description	Probable low-affinity copper uptake protein 2 (hCTR2) (Copper transporter 2) (Solute carrier family 31 member 2).

INOC1_HUMAN
NC score	0.018280 (rank : 189)	θ value	0.47712 (rank : 123)
Query Neighborhood Hits	332	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

RFIP1_HUMAN
NC score	0.017892 (rank : 190)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	332	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

APXL_HUMAN
NC score	0.017804 (rank : 191)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	332	Target Neighborhood Hits	553	Shared Neighborhood Hits	57
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ESPL1_HUMAN
NC score	0.017790 (rank : 192)	θ value	0.813845 (rank : 136)
Query Neighborhood Hits	332	Target Neighborhood Hits	95	Shared Neighborhood Hits	15
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

INOC1_MOUSE
NC score	0.017759 (rank : 193)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	332	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

NCKX1_HUMAN
NC score	0.017563 (rank : 194)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	332	Target Neighborhood Hits	223	Shared Neighborhood Hits	30
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

ANK2_HUMAN
NC score	0.017511 (rank : 195)	θ value	0.0431538 (rank : 91)
Query Neighborhood Hits	332	Target Neighborhood Hits	1615	Shared Neighborhood Hits	106
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

DHX33_MOUSE
NC score	0.017326 (rank : 196)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	332	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

ZN750_HUMAN
NC score	0.017304 (rank : 197)	θ value	1.81305 (rank : 183)
Query Neighborhood Hits	332	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

RYR1_HUMAN
NC score	0.017263 (rank : 198)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	332	Target Neighborhood Hits	303	Shared Neighborhood Hits	29
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

JARD2_MOUSE
NC score	0.016704 (rank : 199)	θ value	2.36792 (rank : 193)
Query Neighborhood Hits	332	Target Neighborhood Hits	169	Shared Neighborhood Hits	21
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

MLL2_HUMAN
NC score	0.016691 (rank : 200)	θ value	6.88961 (rank : 280)
Query Neighborhood Hits	332	Target Neighborhood Hits	1788	Shared Neighborhood Hits	113
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TXLNA_HUMAN
NC score	0.016611 (rank : 201)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	332	Target Neighborhood Hits	982	Shared Neighborhood Hits	95
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

UBP42_HUMAN
NC score	0.016608 (rank : 202)	θ value	3.0926 (rank : 215)
Query Neighborhood Hits	332	Target Neighborhood Hits	445	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

RIMB1_HUMAN
NC score	0.016149 (rank : 203)	θ value	1.06291 (rank : 150)
Query Neighborhood Hits	332	Target Neighborhood Hits	1479	Shared Neighborhood Hits	96
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

HDGF_MOUSE
NC score	0.016041 (rank : 204)	θ value	1.06291 (rank : 144)
Query Neighborhood Hits	332	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

MY18B_HUMAN
NC score	0.015949 (rank : 205)	θ value	1.38821 (rank : 158)
Query Neighborhood Hits	332	Target Neighborhood Hits	1299	Shared Neighborhood Hits	98
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

DHX33_HUMAN
NC score	0.015891 (rank : 206)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	332	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

SIAL_MOUSE
NC score	0.015765 (rank : 207)	θ value	8.99809 (rank : 327)
Query Neighborhood Hits	332	Target Neighborhood Hits	69	Shared Neighborhood Hits	11
SwissProt Accessions	Q61711, Q61363	Gene names	Ibsp
Domain Architecture
Description	Bone sialoprotein-2 precursor (Bone sialoprotein II) (BSP II) (Cell- binding sialoprotein) (Integrin-binding sialoprotein).

EGLN2_MOUSE
NC score	0.015525 (rank : 208)	θ value	0.365318 (rank : 118)
Query Neighborhood Hits	332	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YE2, Q8C6I4, Q8CIL9, Q8VHJ1, Q99MI0	Gene names	Egln2
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (Falkor).

COCA1_HUMAN
NC score	0.015518 (rank : 209)	θ value	4.03905 (rank : 218)
Query Neighborhood Hits	332	Target Neighborhood Hits	458	Shared Neighborhood Hits	51
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
NC score	0.015431 (rank : 210)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	332	Target Neighborhood Hits	467	Shared Neighborhood Hits	50
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

JPH2_MOUSE
NC score	0.015267 (rank : 211)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	332	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

BIN1_HUMAN
NC score	0.015204 (rank : 212)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	332	Target Neighborhood Hits	335	Shared Neighborhood Hits	33
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

TXLNB_HUMAN
NC score	0.014999 (rank : 213)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	332	Target Neighborhood Hits	912	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ARHG1_HUMAN
NC score	0.014948 (rank : 214)	θ value	0.0961366 (rank : 102)
Query Neighborhood Hits	332	Target Neighborhood Hits	176	Shared Neighborhood Hits	25
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

MILK1_HUMAN
NC score	0.014897 (rank : 215)	θ value	1.06291 (rank : 147)
Query Neighborhood Hits	332	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TCF20_MOUSE
NC score	0.014893 (rank : 216)	θ value	8.99809 (rank : 330)
Query Neighborhood Hits	332	Target Neighborhood Hits	396	Shared Neighborhood Hits	44
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

SMG5_HUMAN
NC score	0.014812 (rank : 217)	θ value	3.0926 (rank : 211)
Query Neighborhood Hits	332	Target Neighborhood Hits	180	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

SC24C_HUMAN
NC score	0.014797 (rank : 218)	θ value	5.27518 (rank : 258)
Query Neighborhood Hits	332	Target Neighborhood Hits	662	Shared Neighborhood Hits	59
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PTSS2_HUMAN
NC score	0.014758 (rank : 219)	θ value	1.06291 (rank : 149)
Query Neighborhood Hits	332	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BVG9	Gene names	PTDSS2, PSS2
Domain Architecture
Description	Phosphatidylserine synthase 2 (EC 2.7.8.-) (PtdSer synthase 2) (PSS-2) (Serine-exchange enzyme II).

PHAR3_HUMAN
NC score	0.014737 (rank : 220)	θ value	2.36792 (rank : 196)
Query Neighborhood Hits	332	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

LEG3_HUMAN
NC score	0.014589 (rank : 221)	θ value	2.36792 (rank : 194)
Query Neighborhood Hits	332	Target Neighborhood Hits	124	Shared Neighborhood Hits	23
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

DGKK_HUMAN
NC score	0.014391 (rank : 222)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	332	Target Neighborhood Hits	378	Shared Neighborhood Hits	33
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

HRX_HUMAN
NC score	0.014059 (rank : 223)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	332	Target Neighborhood Hits	825	Shared Neighborhood Hits	56
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SH3BG_HUMAN
NC score	0.013337 (rank : 224)	θ value	8.99809 (rank : 326)
Query Neighborhood Hits	332	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	P55822, Q9BRB8	Gene names	SH3BGR
Domain Architecture
Description	SH3 domain-binding glutamic acid-rich protein (SH3BGR protein) (21- glutamic acid-rich protein) (21-GARP).

ADDA_HUMAN
NC score	0.013284 (rank : 225)	θ value	1.06291 (rank : 140)
Query Neighborhood Hits	332	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

BCL7A_HUMAN
NC score	0.013195 (rank : 226)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	332	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

TERF1_HUMAN
NC score	0.012971 (rank : 227)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	332	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	P54274, Q15553, Q93029	Gene names	TERF1, PIN2, TRF, TRF1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1).

SEN34_HUMAN
NC score	0.012783 (rank : 228)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	332	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BSV6, Q9BVT1, Q9H6H5	Gene names	TSEN34, LENG5, SEN34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (HsSen34) (Leukocyte receptor cluster member 5).

H6ST3_HUMAN
NC score	0.012745 (rank : 229)	θ value	1.38821 (rank : 155)
Query Neighborhood Hits	332	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

SYNPO_HUMAN
NC score	0.012584 (rank : 230)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	332	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

AFF2_HUMAN
NC score	0.012559 (rank : 231)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	332	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

IQEC3_HUMAN
NC score	0.012279 (rank : 232)	θ value	0.813845 (rank : 137)
Query Neighborhood Hits	332	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

CSKI1_HUMAN
NC score	0.012241 (rank : 233)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	332	Target Neighborhood Hits	997	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

REXO1_MOUSE
NC score	0.011968 (rank : 234)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	332	Target Neighborhood Hits	166	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

NFM_HUMAN
NC score	0.011928 (rank : 235)	θ value	0.813845 (rank : 138)
Query Neighborhood Hits	332	Target Neighborhood Hits	1328	Shared Neighborhood Hits	65
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

TEX2_MOUSE
NC score	0.011770 (rank : 236)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	332	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

RFIP3_HUMAN
NC score	0.011668 (rank : 237)	θ value	0.813845 (rank : 139)
Query Neighborhood Hits	332	Target Neighborhood Hits	1055	Shared Neighborhood Hits	51
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP1_MOUSE
NC score	0.011637 (rank : 238)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	332	Target Neighborhood Hits	152	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

LBXCO_HUMAN
NC score	0.011580 (rank : 239)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	332	Target Neighborhood Hits	167	Shared Neighborhood Hits	23
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

CENPB_MOUSE
NC score	0.011558 (rank : 240)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	332	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

ZGPAT_MOUSE
NC score	0.011457 (rank : 241)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	332	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

AKP8L_MOUSE
NC score	0.011221 (rank : 242)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	332	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

EDN3_MOUSE
NC score	0.011161 (rank : 243)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	332	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P48299, Q543L0	Gene names	Edn3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

SCND1_HUMAN
NC score	0.011113 (rank : 244)	θ value	0.163984 (rank : 110)
Query Neighborhood Hits	332	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	P57086	Gene names	SCAND1, SDP1
Domain Architecture
Description	SCAN domain-containing protein 1.

CP053_HUMAN
NC score	0.011083 (rank : 245)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	332	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

YBOX2_MOUSE
NC score	0.011006 (rank : 246)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	332	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

JADE2_HUMAN
NC score	0.010890 (rank : 247)	θ value	1.38821 (rank : 156)
Query Neighborhood Hits	332	Target Neighborhood Hits	199	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

SMRD3_HUMAN
NC score	0.010776 (rank : 248)	θ value	3.0926 (rank : 212)
Query Neighborhood Hits	332	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q6STE5, Q75MJ2, Q75MR8, Q92926, Q9BUH1	Gene names	SMARCD3, BAF60C
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C).

SYTL1_HUMAN
NC score	0.010558 (rank : 249)	θ value	1.38821 (rank : 163)
Query Neighborhood Hits	332	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SMRD3_MOUSE
NC score	0.010347 (rank : 250)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	332	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P9Z1, Q921D3, Q9CX89, Q9DB99	Gene names	Smarcd3, Baf60c
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (mBAF60c).

CCD96_HUMAN
NC score	0.010066 (rank : 251)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	332	Target Neighborhood Hits	595	Shared Neighborhood Hits	44
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

ZMYM3_HUMAN
NC score	0.010002 (rank : 252)	θ value	6.88961 (rank : 295)
Query Neighborhood Hits	332	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

THAP3_HUMAN
NC score	0.009634 (rank : 253)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	332	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WTV1, Q569K1, Q5TH66, Q5TH67, Q8N8T6, Q9BSC7, Q9Y3H2, Q9Y3H3	Gene names	THAP3
Domain Architecture
Description	THAP domain-containing protein 3.

ANR47_HUMAN
NC score	0.009633 (rank : 254)	θ value	1.38821 (rank : 151)
Query Neighborhood Hits	332	Target Neighborhood Hits	369	Shared Neighborhood Hits	20
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NFL_MOUSE
NC score	0.009217 (rank : 255)	θ value	0.47712 (rank : 124)
Query Neighborhood Hits	332	Target Neighborhood Hits	695	Shared Neighborhood Hits	30
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

DEDD2_HUMAN
NC score	0.008694 (rank : 256)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	332	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXF8, Q8NBR2, Q8NES1, Q8TAA8, Q96D35	Gene names	DEDD2, FLAME3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

NFM_MOUSE
NC score	0.008596 (rank : 257)	θ value	1.38821 (rank : 160)
Query Neighborhood Hits	332	Target Neighborhood Hits	1159	Shared Neighborhood Hits	46
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

AIPL1_HUMAN
NC score	0.008327 (rank : 258)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	332	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZN9, Q9H873, Q9NS10	Gene names	AIPL1
Domain Architecture
Description	Aryl-hydrocarbon-interacting protein-like 1.

SIRT1_MOUSE
NC score	0.008298 (rank : 259)	θ value	3.0926 (rank : 210)
Query Neighborhood Hits	332	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

LDB3_HUMAN
NC score	0.008163 (rank : 260)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	332	Target Neighborhood Hits	497	Shared Neighborhood Hits	24
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

E41L1_HUMAN
NC score	0.008034 (rank : 261)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	332	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

GBF1_HUMAN
NC score	0.008022 (rank : 262)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	332	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

UBP10_MOUSE
NC score	0.007891 (rank : 263)	θ value	6.88961 (rank : 293)
Query Neighborhood Hits	332	Target Neighborhood Hits	150	Shared Neighborhood Hits	16
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

PRDM8_MOUSE
NC score	0.007884 (rank : 264)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	332	Target Neighborhood Hits	176	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BZ97	Gene names	Prdm8
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

AMYP_HUMAN
NC score	0.007761 (rank : 265)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	332	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P04746, Q9UBH3	Gene names	AMY2A
Domain Architecture
Description	Pancreatic alpha-amylase precursor (EC 3.2.1.1) (PA) (1,4-alpha-D- glucan glucanohydrolase).

PABP2_MOUSE
NC score	0.007641 (rank : 266)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	332	Target Neighborhood Hits	214	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

NFL_HUMAN
NC score	0.007577 (rank : 267)	θ value	6.88961 (rank : 282)
Query Neighborhood Hits	332	Target Neighborhood Hits	666	Shared Neighborhood Hits	30
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

LNK_HUMAN
NC score	0.007576 (rank : 268)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	332	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

U383_HUMAN
NC score	0.007099 (rank : 269)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	332	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYL2	Gene names	C4orf23
Domain Architecture	No domain graphic available
Description	Putative methyltransferase UPF0383 (EC 2.1.1.-).

MYPC2_HUMAN
NC score	0.007088 (rank : 270)	θ value	1.38821 (rank : 159)
Query Neighborhood Hits	332	Target Neighborhood Hits	316	Shared Neighborhood Hits	9
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

FBX42_HUMAN
NC score	0.006837 (rank : 271)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	332	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

LDB3_MOUSE
NC score	0.006718 (rank : 272)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	332	Target Neighborhood Hits	510	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

T240L_HUMAN
NC score	0.006592 (rank : 273)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	332	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

CABP4_HUMAN
NC score	0.006510 (rank : 274)	θ value	0.813845 (rank : 132)
Query Neighborhood Hits	332	Target Neighborhood Hits	250	Shared Neighborhood Hits	16
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

PER1_HUMAN
NC score	0.006086 (rank : 275)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	332	Target Neighborhood Hits	215	Shared Neighborhood Hits	18
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

AP3B2_HUMAN
NC score	0.005986 (rank : 276)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	332	Target Neighborhood Hits	246	Shared Neighborhood Hits	24
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

RGP2_HUMAN
NC score	0.005947 (rank : 277)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	332	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

TOPB1_HUMAN
NC score	0.005913 (rank : 278)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	332	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

CUTL1_MOUSE
NC score	0.005794 (rank : 279)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	332	Target Neighborhood Hits	1620	Shared Neighborhood Hits	74
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

HUWE1_HUMAN
NC score	0.005695 (rank : 280)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	332	Target Neighborhood Hits	443	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

PR285_HUMAN
NC score	0.005515 (rank : 281)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	332	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

MYPC2_MOUSE
NC score	0.005378 (rank : 282)	θ value	6.88961 (rank : 281)
Query Neighborhood Hits	332	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

DVL2_HUMAN
NC score	0.005355 (rank : 283)	θ value	3.0926 (rank : 207)
Query Neighborhood Hits	332	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

FARP1_HUMAN
NC score	0.005072 (rank : 284)	θ value	1.06291 (rank : 142)
Query Neighborhood Hits	332	Target Neighborhood Hits	241	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

ANKY2_MOUSE
NC score	0.004872 (rank : 285)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	332	Target Neighborhood Hits	316	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

HXC11_HUMAN
NC score	0.004601 (rank : 286)	θ value	0.47712 (rank : 122)
Query Neighborhood Hits	332	Target Neighborhood Hits	349	Shared Neighborhood Hits	14
SwissProt Accessions	O43248, Q96DH2	Gene names	HOXC11
Domain Architecture
Description	Homeobox protein Hox-C11.

KI13B_HUMAN
NC score	0.004402 (rank : 287)	θ value	1.38821 (rank : 157)
Query Neighborhood Hits	332	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

DNL3_HUMAN
NC score	0.004196 (rank : 288)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	332	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

GBP2_MOUSE
NC score	0.004112 (rank : 289)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	332	Target Neighborhood Hits	323	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

FBXW8_HUMAN
NC score	0.004100 (rank : 290)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	332	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

DYNA_MOUSE
NC score	0.004065 (rank : 291)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	332	Target Neighborhood Hits	1084	Shared Neighborhood Hits	33
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

SPEG_MOUSE
NC score	0.003737 (rank : 292)	θ value	0.47712 (rank : 125)
Query Neighborhood Hits	332	Target Neighborhood Hits	1959	Shared Neighborhood Hits	94
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

WDR79_HUMAN
NC score	0.003495 (rank : 293)	θ value	8.99809 (rank : 331)
Query Neighborhood Hits	332	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

HAND1_MOUSE
NC score	0.002998 (rank : 294)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	332	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

DYNA_HUMAN
NC score	0.002972 (rank : 295)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	332	Target Neighborhood Hits	1194	Shared Neighborhood Hits	37
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

CEND1_HUMAN
NC score	0.002962 (rank : 296)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	332	Target Neighborhood Hits	284	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

FOG1_HUMAN
NC score	0.002807 (rank : 297)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	332	Target Neighborhood Hits	981	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CUTL1_HUMAN
NC score	0.002675 (rank : 298)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	332	Target Neighborhood Hits	1574	Shared Neighborhood Hits	56
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

HXB4_MOUSE
NC score	0.002451 (rank : 299)	θ value	1.06291 (rank : 145)
Query Neighborhood Hits	332	Target Neighborhood Hits	375	Shared Neighborhood Hits	15
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

PVRL2_HUMAN
NC score	0.002379 (rank : 300)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	332	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

KCNH2_MOUSE
NC score	0.002241 (rank : 301)	θ value	6.88961 (rank : 277)
Query Neighborhood Hits	332	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

SPEG_HUMAN
NC score	0.001667 (rank : 302)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	332	Target Neighborhood Hits	1762	Shared Neighborhood Hits	84
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

HXB4_HUMAN
NC score	0.001349 (rank : 303)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	332	Target Neighborhood Hits	376	Shared Neighborhood Hits	18
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

GMIP_HUMAN
NC score	0.001209 (rank : 304)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	332	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

ZHX1_MOUSE
NC score	0.001205 (rank : 305)	θ value	8.99809 (rank : 332)
Query Neighborhood Hits	332	Target Neighborhood Hits	334	Shared Neighborhood Hits	11
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

HXA13_HUMAN
NC score	0.000984 (rank : 306)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	332	Target Neighborhood Hits	353	Shared Neighborhood Hits	13
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

SREC2_HUMAN
NC score	0.000556 (rank : 307)	θ value	8.99809 (rank : 329)
Query Neighborhood Hits	332	Target Neighborhood Hits	645	Shared Neighborhood Hits	25
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

HXD4_HUMAN
NC score	0.000455 (rank : 308)	θ value	6.88961 (rank : 276)
Query Neighborhood Hits	332	Target Neighborhood Hits	337	Shared Neighborhood Hits	13
SwissProt Accessions	P09016, Q96AU0	Gene names	HOXD4, HOX4B
Domain Architecture
Description	Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13).

HHEX_MOUSE
NC score	0.000177 (rank : 309)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	332	Target Neighborhood Hits	350	Shared Neighborhood Hits	8
SwissProt Accessions	P43120	Gene names	Hhex, Prhx
Domain Architecture
Description	Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX).

TMPSD_HUMAN
NC score	-0.000059 (rank : 310)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	332	Target Neighborhood Hits	333	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

AATK_HUMAN
NC score	-0.000117 (rank : 311)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	332	Target Neighborhood Hits	1243	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

TRI17_HUMAN
NC score	-0.000147 (rank : 312)	θ value	1.81305 (rank : 182)
Query Neighborhood Hits	332	Target Neighborhood Hits	318	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TTBK1_HUMAN
NC score	-0.000281 (rank : 313)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	332	Target Neighborhood Hits	1058	Shared Neighborhood Hits	47
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ERR1_HUMAN
NC score	-0.000301 (rank : 314)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	332	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

MYLK2_HUMAN
NC score	-0.000954 (rank : 315)	θ value	0.21417 (rank : 113)
Query Neighborhood Hits	332	Target Neighborhood Hits	920	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

WNK2_HUMAN
NC score	-0.001327 (rank : 316)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	332	Target Neighborhood Hits	1407	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

BARX1_MOUSE
NC score	-0.001387 (rank : 317)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	332	Target Neighborhood Hits	324	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER42, O09066, P70159, Q9ERV2	Gene names	Barx1
Domain Architecture
Description	Homeobox protein BarH-like 1.

FYCO1_HUMAN
NC score	-0.001562 (rank : 318)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	332	Target Neighborhood Hits	1149	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

OBSCN_HUMAN
NC score	-0.001573 (rank : 319)	θ value	1.38821 (rank : 161)
Query Neighborhood Hits	332	Target Neighborhood Hits	1931	Shared Neighborhood Hits	81
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

AATK_MOUSE
NC score	-0.001727 (rank : 320)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	332	Target Neighborhood Hits	942	Shared Neighborhood Hits	38
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

SALL3_HUMAN
NC score	-0.002363 (rank : 321)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	332	Target Neighborhood Hits	1066	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

FBLN2_HUMAN
NC score	-0.002559 (rank : 322)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	332	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LGR4_HUMAN
NC score	-0.002632 (rank : 323)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	332	Target Neighborhood Hits	481	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

RREB1_HUMAN
NC score	-0.002999 (rank : 324)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	332	Target Neighborhood Hits	879	Shared Neighborhood Hits	39
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

ABL1_HUMAN
NC score	-0.003383 (rank : 325)	θ value	0.163984 (rank : 104)
Query Neighborhood Hits	332	Target Neighborhood Hits	1220	Shared Neighborhood Hits	47
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

LRSM1_MOUSE
NC score	-0.003697 (rank : 326)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	332	Target Neighborhood Hits	874	Shared Neighborhood Hits	20
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

ZN592_HUMAN
NC score	-0.003808 (rank : 327)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	332	Target Neighborhood Hits	762	Shared Neighborhood Hits	22
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

ZN516_HUMAN
NC score	-0.004262 (rank : 328)	θ value	6.88961 (rank : 296)
Query Neighborhood Hits	332	Target Neighborhood Hits	854	Shared Neighborhood Hits	40
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

PAK4_MOUSE
NC score	-0.004355 (rank : 329)	θ value	2.36792 (rank : 195)
Query Neighborhood Hits	332	Target Neighborhood Hits	1098	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SP7_MOUSE
NC score	-0.005140 (rank : 330)	θ value	3.0926 (rank : 213)
Query Neighborhood Hits	332	Target Neighborhood Hits	756	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

SP7_HUMAN
NC score	-0.005343 (rank : 331)	θ value	8.99809 (rank : 328)
Query Neighborhood Hits	332	Target Neighborhood Hits	734	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

KLF15_HUMAN
NC score	-0.005527 (rank : 332)	θ value	3.0926 (rank : 209)
Query Neighborhood Hits	332	Target Neighborhood Hits	720	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIH9	Gene names	KLF15, KKLF
Domain Architecture
Description	Krueppel-like factor 15 (Kidney-enriched krueppel-like factor).

ZBT40_HUMAN
NC score	-0.005920 (rank : 333)	θ value	1.38821 (rank : 164)
Query Neighborhood Hits	332	Target Neighborhood Hits	949	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

KLF14_HUMAN
NC score	-0.006140 (rank : 334)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	332	Target Neighborhood Hits	725	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

GFI1_HUMAN
NC score	-0.006298 (rank : 335)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	332	Target Neighborhood Hits	726	Shared Neighborhood Hits	17
SwissProt Accessions	Q99684, Q8N564	Gene names	GFI1, ZNF163
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

ZN646_HUMAN
NC score	-0.006426 (rank : 336)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	332	Target Neighborhood Hits	813	Shared Neighborhood Hits	22
SwissProt Accessions	O15015	Gene names	ZNF646, KIAA0296
Domain Architecture	No domain graphic available
Description	Zinc finger protein 646.