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Network neighborhood for query Sequence : SIRT1_MOUSE

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SIRT1_MOUSE
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SIRT1_HUMAN
θ value	0 (rank : 1)	NC score	0.991419 (rank : 2)
Query Neighborhood Hits	50	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

SIRT1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	50
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

SIRT2_MOUSE
θ value	1.51013e-55 (rank : 3)	NC score	0.906312 (rank : 3)
Query Neighborhood Hits	50	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VDQ8, Q9CXS5, Q9EQ18, Q9ERJ9	Gene names	Sirt2, Sir2l2
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-2 (EC 3.5.1.-) (SIR2-like protein 2) (mSIR2L2).

SIRT2_HUMAN
θ value	4.11246e-53 (rank : 4)	NC score	0.903581 (rank : 5)
Query Neighborhood Hits	50	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IXJ6, O95889, Q924Y7, Q9P0G8, Q9UNT0, Q9Y6E9	Gene names	SIRT2, SIR2L, SIR2L2
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-2 (EC 3.5.1.-) (SIR2-like) (SIR2- like protein 2).

SIRT3_HUMAN
θ value	2.75849e-49 (rank : 5)	NC score	0.903688 (rank : 4)
Query Neighborhood Hits	50	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NTG7, Q9Y6E8	Gene names	SIRT3, SIR2L3
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-3, mitochondrial precursor (EC 3.5.1.-) (SIR2-like protein 3) (hSIRT3).

SIRT3_MOUSE
θ value	2.26182e-43 (rank : 6)	NC score	0.902608 (rank : 6)
Query Neighborhood Hits	50	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R104, Q9EPA8	Gene names	Sirt3, Sir2l3
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-3 (EC 3.5.1.-) (SIR2-like protein 3) (mSIR2L3).

SIRT5_HUMAN
θ value	2.97466e-19 (rank : 7)	NC score	0.725411 (rank : 7)
Query Neighborhood Hits	50	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NXA8, Q9Y6E6	Gene names	SIRT5, SIR2L5
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-5 (EC 3.5.1.-) (SIR2-like protein 5).

SIRT4_MOUSE
θ value	8.10077e-17 (rank : 8)	NC score	0.699954 (rank : 9)
Query Neighborhood Hits	50	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R216	Gene names	Sirt4, Sir2l4
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-4 (EC 3.5.1.-) (SIR2-like protein 4).

SIRT5_MOUSE
θ value	4.02038e-16 (rank : 9)	NC score	0.716122 (rank : 8)
Query Neighborhood Hits	50	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K2C6	Gene names	Sirt5, Sir2l5
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-5 (EC 3.5.1.-) (SIR2-like protein 5).

SIRT4_HUMAN
θ value	4.44505e-15 (rank : 10)	NC score	0.697516 (rank : 10)
Query Neighborhood Hits	50	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6E7, O43346	Gene names	SIRT4, SIR2L4
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-4 (EC 3.5.1.-) (SIR2-like protein 4).

SIRT6_HUMAN
θ value	1.33837e-11 (rank : 11)	NC score	0.619091 (rank : 11)
Query Neighborhood Hits	50	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N6T7, O75291, Q6IAF5, Q6PK99, Q8NCD2, Q9BSI5, Q9BWP3, Q9NRC7, Q9UQD1	Gene names	SIRT6, SIR2L6
Domain Architecture
Description	Mono-ADP-ribosyltransferase sirtuin-6 (EC 2.4.2.31) (SIR2-like protein 6).

SIRT6_MOUSE
θ value	2.52405e-10 (rank : 12)	NC score	0.603922 (rank : 12)
Query Neighborhood Hits	50	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P59941	Gene names	Sirt6, Sir2l6
Domain Architecture
Description	Mono-ADP-ribosyltransferase sirtuin-6 (EC 2.4.2.31) (SIR2-like protein 6).

SIRT7_MOUSE
θ value	1.43324e-05 (rank : 13)	NC score	0.516524 (rank : 13)
Query Neighborhood Hits	50	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BKJ9, Q6X7B7, Q8QZZ5	Gene names	Sirt7, Sir2l7
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-7 (EC 3.5.1.-) (SIR2-like protein 7).

SIRT7_HUMAN
θ value	0.000121331 (rank : 14)	NC score	0.505603 (rank : 14)
Query Neighborhood Hits	50	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRC8, Q3MIK4, Q9NSZ6, Q9NUS6	Gene names	SIRT7, SIR2L7
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-7 (EC 3.5.1.-) (SIR2-like protein 7).

L2GL1_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.030867 (rank : 17)
Query Neighborhood Hits	50	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q15334, O00188, Q58F11, Q86UK6	Gene names	LLGL1, HUGL
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Human homolog to the D-lgl gene) (Hugl-1) (DLG4).

NFH_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.009946 (rank : 35)
Query Neighborhood Hits	50	Target Neighborhood Hits	1242	Shared Neighborhood Hits	14
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CD2L2_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.002451 (rank : 47)
Query Neighborhood Hits	50	Target Neighborhood Hits	1439	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

PHF8_MOUSE
θ value	1.06291 (rank : 18)	NC score	0.020833 (rank : 19)
Query Neighborhood Hits	50	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

CPSF1_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.039026 (rank : 16)
Query Neighborhood Hits	50	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q10570, Q96AF0	Gene names	CPSF1, CPSF160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

CPSF1_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.039080 (rank : 15)
Query Neighborhood Hits	50	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

PHLB2_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.021208 (rank : 18)
Query Neighborhood Hits	50	Target Neighborhood Hits	964	Shared Neighborhood Hits	10
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SYCP1_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.006522 (rank : 41)
Query Neighborhood Hits	50	Target Neighborhood Hits	1456	Shared Neighborhood Hits	14
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

NCOA3_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.019642 (rank : 20)
Query Neighborhood Hits	50	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NRK_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.002284 (rank : 48)
Query Neighborhood Hits	50	Target Neighborhood Hits	931	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

DDX51_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.008298 (rank : 38)
Query Neighborhood Hits	50	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

IWS1_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.012305 (rank : 29)
Query Neighborhood Hits	50	Target Neighborhood Hits	1258	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RIMB1_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.014423 (rank : 27)
Query Neighborhood Hits	50	Target Neighborhood Hits	1479	Shared Neighborhood Hits	14
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.015979 (rank : 24)
Query Neighborhood Hits	50	Target Neighborhood Hits	263	Shared Neighborhood Hits	4
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SON_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.010256 (rank : 34)
Query Neighborhood Hits	50	Target Neighborhood Hits	1568	Shared Neighborhood Hits	15
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.017095 (rank : 22)
Query Neighborhood Hits	50	Target Neighborhood Hits	957	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

DOC10_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.009194 (rank : 36)
Query Neighborhood Hits	50	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

ITCH_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.005187 (rank : 46)
Query Neighborhood Hits	50	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

LRRK1_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.000837 (rank : 49)
Query Neighborhood Hits	50	Target Neighborhood Hits	1267	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

RNF25_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.016137 (rank : 23)
Query Neighborhood Hits	50	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

ANR12_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.009175 (rank : 37)
Query Neighborhood Hits	50	Target Neighborhood Hits	1081	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

BPTF_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.012559 (rank : 28)
Query Neighborhood Hits	50	Target Neighborhood Hits	786	Shared Neighborhood Hits	19
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CD36_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.010449 (rank : 32)
Query Neighborhood Hits	50	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q08857	Gene names	Cd36
Domain Architecture
Description	Platelet glycoprotein 4 (Platelet glycoprotein IV) (GPIV) (GPIIIB) (CD36 antigen) (PAS IV) (PAS-4 protein).

ELF4_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.006295 (rank : 42)
Query Neighborhood Hits	50	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

MDN1_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.015328 (rank : 26)
Query Neighborhood Hits	50	Target Neighborhood Hits	662	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PININ_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.010256 (rank : 33)
Query Neighborhood Hits	50	Target Neighborhood Hits	777	Shared Neighborhood Hits	12
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

REPS1_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.011517 (rank : 30)
Query Neighborhood Hits	50	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RTN4_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.010608 (rank : 31)
Query Neighborhood Hits	50	Target Neighborhood Hits	357	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SCN3A_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.005972 (rank : 44)
Query Neighborhood Hits	50	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SOX13_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.005752 (rank : 45)
Query Neighborhood Hits	50	Target Neighborhood Hits	495	Shared Neighborhood Hits	4
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

CBP_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.005988 (rank : 43)
Query Neighborhood Hits	50	Target Neighborhood Hits	1051	Shared Neighborhood Hits	12
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

IF4G3_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.019130 (rank : 21)
Query Neighborhood Hits	50	Target Neighborhood Hits	247	Shared Neighborhood Hits	9
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

MAGA5_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.007319 (rank : 39)
Query Neighborhood Hits	50	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P43359	Gene names	MAGEA5, MAGE5
Domain Architecture
Description	Melanoma-associated antigen 5 (MAGE-5 antigen).

NEK1_HUMAN
θ value	8.99809 (rank : 48)	NC score	-0.000314 (rank : 50)
Query Neighborhood Hits	50	Target Neighborhood Hits	1129	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

PHF8_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.015571 (rank : 25)
Query Neighborhood Hits	50	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

SCN2A_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.007159 (rank : 40)
Query Neighborhood Hits	50	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

Hits sorted by NC score

SIRT1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	50
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

SIRT1_HUMAN
NC score	0.991419 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	50	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

SIRT2_MOUSE
NC score	0.906312 (rank : 3)	θ value	1.51013e-55 (rank : 3)
Query Neighborhood Hits	50	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VDQ8, Q9CXS5, Q9EQ18, Q9ERJ9	Gene names	Sirt2, Sir2l2
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-2 (EC 3.5.1.-) (SIR2-like protein 2) (mSIR2L2).

SIRT3_HUMAN
NC score	0.903688 (rank : 4)	θ value	2.75849e-49 (rank : 5)
Query Neighborhood Hits	50	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NTG7, Q9Y6E8	Gene names	SIRT3, SIR2L3
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-3, mitochondrial precursor (EC 3.5.1.-) (SIR2-like protein 3) (hSIRT3).

SIRT2_HUMAN
NC score	0.903581 (rank : 5)	θ value	4.11246e-53 (rank : 4)
Query Neighborhood Hits	50	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IXJ6, O95889, Q924Y7, Q9P0G8, Q9UNT0, Q9Y6E9	Gene names	SIRT2, SIR2L, SIR2L2
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-2 (EC 3.5.1.-) (SIR2-like) (SIR2- like protein 2).

SIRT3_MOUSE
NC score	0.902608 (rank : 6)	θ value	2.26182e-43 (rank : 6)
Query Neighborhood Hits	50	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R104, Q9EPA8	Gene names	Sirt3, Sir2l3
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-3 (EC 3.5.1.-) (SIR2-like protein 3) (mSIR2L3).

SIRT5_HUMAN
NC score	0.725411 (rank : 7)	θ value	2.97466e-19 (rank : 7)
Query Neighborhood Hits	50	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NXA8, Q9Y6E6	Gene names	SIRT5, SIR2L5
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-5 (EC 3.5.1.-) (SIR2-like protein 5).

SIRT5_MOUSE
NC score	0.716122 (rank : 8)	θ value	4.02038e-16 (rank : 9)
Query Neighborhood Hits	50	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K2C6	Gene names	Sirt5, Sir2l5
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-5 (EC 3.5.1.-) (SIR2-like protein 5).

SIRT4_MOUSE
NC score	0.699954 (rank : 9)	θ value	8.10077e-17 (rank : 8)
Query Neighborhood Hits	50	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R216	Gene names	Sirt4, Sir2l4
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-4 (EC 3.5.1.-) (SIR2-like protein 4).

SIRT4_HUMAN
NC score	0.697516 (rank : 10)	θ value	4.44505e-15 (rank : 10)
Query Neighborhood Hits	50	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6E7, O43346	Gene names	SIRT4, SIR2L4
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-4 (EC 3.5.1.-) (SIR2-like protein 4).

SIRT6_HUMAN
NC score	0.619091 (rank : 11)	θ value	1.33837e-11 (rank : 11)
Query Neighborhood Hits	50	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N6T7, O75291, Q6IAF5, Q6PK99, Q8NCD2, Q9BSI5, Q9BWP3, Q9NRC7, Q9UQD1	Gene names	SIRT6, SIR2L6
Domain Architecture
Description	Mono-ADP-ribosyltransferase sirtuin-6 (EC 2.4.2.31) (SIR2-like protein 6).

SIRT6_MOUSE
NC score	0.603922 (rank : 12)	θ value	2.52405e-10 (rank : 12)
Query Neighborhood Hits	50	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P59941	Gene names	Sirt6, Sir2l6
Domain Architecture
Description	Mono-ADP-ribosyltransferase sirtuin-6 (EC 2.4.2.31) (SIR2-like protein 6).

SIRT7_MOUSE
NC score	0.516524 (rank : 13)	θ value	1.43324e-05 (rank : 13)
Query Neighborhood Hits	50	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BKJ9, Q6X7B7, Q8QZZ5	Gene names	Sirt7, Sir2l7
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-7 (EC 3.5.1.-) (SIR2-like protein 7).

SIRT7_HUMAN
NC score	0.505603 (rank : 14)	θ value	0.000121331 (rank : 14)
Query Neighborhood Hits	50	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRC8, Q3MIK4, Q9NSZ6, Q9NUS6	Gene names	SIRT7, SIR2L7
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-7 (EC 3.5.1.-) (SIR2-like protein 7).

CPSF1_MOUSE
NC score	0.039080 (rank : 15)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	50	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

CPSF1_HUMAN
NC score	0.039026 (rank : 16)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	50	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q10570, Q96AF0	Gene names	CPSF1, CPSF160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

L2GL1_HUMAN
NC score	0.030867 (rank : 17)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	50	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q15334, O00188, Q58F11, Q86UK6	Gene names	LLGL1, HUGL
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Human homolog to the D-lgl gene) (Hugl-1) (DLG4).

PHLB2_HUMAN
NC score	0.021208 (rank : 18)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	50	Target Neighborhood Hits	964	Shared Neighborhood Hits	10
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHF8_MOUSE
NC score	0.020833 (rank : 19)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	50	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

NCOA3_MOUSE
NC score	0.019642 (rank : 20)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	50	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

IF4G3_HUMAN
NC score	0.019130 (rank : 21)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	50	Target Neighborhood Hits	247	Shared Neighborhood Hits	9
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

SON_MOUSE
NC score	0.017095 (rank : 22)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	50	Target Neighborhood Hits	957	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

RNF25_MOUSE
NC score	0.016137 (rank : 23)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	50	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RIMB2_HUMAN
NC score	0.015979 (rank : 24)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	50	Target Neighborhood Hits	263	Shared Neighborhood Hits	4
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

PHF8_HUMAN
NC score	0.015571 (rank : 25)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	50	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

MDN1_HUMAN
NC score	0.015328 (rank : 26)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	50	Target Neighborhood Hits	662	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RIMB1_HUMAN
NC score	0.014423 (rank : 27)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	50	Target Neighborhood Hits	1479	Shared Neighborhood Hits	14
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BPTF_HUMAN
NC score	0.012559 (rank : 28)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	50	Target Neighborhood Hits	786	Shared Neighborhood Hits	19
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

IWS1_MOUSE
NC score	0.012305 (rank : 29)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	50	Target Neighborhood Hits	1258	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

REPS1_MOUSE
NC score	0.011517 (rank : 30)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	50	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RTN4_HUMAN
NC score	0.010608 (rank : 31)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	50	Target Neighborhood Hits	357	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CD36_MOUSE
NC score	0.010449 (rank : 32)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	50	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q08857	Gene names	Cd36
Domain Architecture
Description	Platelet glycoprotein 4 (Platelet glycoprotein IV) (GPIV) (GPIIIB) (CD36 antigen) (PAS IV) (PAS-4 protein).

PININ_MOUSE
NC score	0.010256 (rank : 33)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	50	Target Neighborhood Hits	777	Shared Neighborhood Hits	12
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SON_HUMAN
NC score	0.010256 (rank : 34)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	50	Target Neighborhood Hits	1568	Shared Neighborhood Hits	15
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NFH_HUMAN
NC score	0.009946 (rank : 35)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	50	Target Neighborhood Hits	1242	Shared Neighborhood Hits	14
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DOC10_HUMAN
NC score	0.009194 (rank : 36)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	50	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

ANR12_HUMAN
NC score	0.009175 (rank : 37)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	50	Target Neighborhood Hits	1081	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

DDX51_HUMAN
NC score	0.008298 (rank : 38)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	50	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

MAGA5_HUMAN
NC score	0.007319 (rank : 39)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	50	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P43359	Gene names	MAGEA5, MAGE5
Domain Architecture
Description	Melanoma-associated antigen 5 (MAGE-5 antigen).

SCN2A_HUMAN
NC score	0.007159 (rank : 40)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	50	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SYCP1_MOUSE
NC score	0.006522 (rank : 41)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	50	Target Neighborhood Hits	1456	Shared Neighborhood Hits	14
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ELF4_MOUSE
NC score	0.006295 (rank : 42)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	50	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

CBP_MOUSE
NC score	0.005988 (rank : 43)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	50	Target Neighborhood Hits	1051	Shared Neighborhood Hits	12
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SCN3A_HUMAN
NC score	0.005972 (rank : 44)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	50	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SOX13_MOUSE
NC score	0.005752 (rank : 45)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	50	Target Neighborhood Hits	495	Shared Neighborhood Hits	4
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

ITCH_HUMAN
NC score	0.005187 (rank : 46)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	50	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

CD2L2_HUMAN
NC score	0.002451 (rank : 47)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	50	Target Neighborhood Hits	1439	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

NRK_HUMAN
NC score	0.002284 (rank : 48)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	50	Target Neighborhood Hits	931	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

LRRK1_MOUSE
NC score	0.000837 (rank : 49)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	50	Target Neighborhood Hits	1267	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

NEK1_HUMAN
NC score	-0.000314 (rank : 50)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	50	Target Neighborhood Hits	1129	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).