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Network neighborhood for query Sequence : RIMB2_HUMAN

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RIMB2_HUMAN
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIMB2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	263	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	0 (rank : 2)	NC score	0.970108 (rank : 2)
Query Neighborhood Hits	263	Target Neighborhood Hits	246	Shared Neighborhood Hits	172
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB1_HUMAN
θ value	4.32305e-111 (rank : 3)	NC score	0.550850 (rank : 3)
Query Neighborhood Hits	263	Target Neighborhood Hits	1479	Shared Neighborhood Hits	170
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
θ value	5.84277e-108 (rank : 4)	NC score	0.484317 (rank : 4)
Query Neighborhood Hits	263	Target Neighborhood Hits	1376	Shared Neighborhood Hits	164
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CD2AP_MOUSE
θ value	2.79066e-09 (rank : 5)	NC score	0.472489 (rank : 5)
Query Neighborhood Hits	263	Target Neighborhood Hits	336	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2AP_HUMAN
θ value	3.08544e-08 (rank : 6)	NC score	0.465959 (rank : 6)
Query Neighborhood Hits	263	Target Neighborhood Hits	315	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

PTPRD_HUMAN
θ value	2.61198e-07 (rank : 7)	NC score	0.180501 (rank : 114)
Query Neighborhood Hits	263	Target Neighborhood Hits	485	Shared Neighborhood Hits	62
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRS_HUMAN
θ value	2.61198e-07 (rank : 8)	NC score	0.184127 (rank : 109)
Query Neighborhood Hits	263	Target Neighborhood Hits	472	Shared Neighborhood Hits	63
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRF_HUMAN
θ value	3.41135e-07 (rank : 9)	NC score	0.171949 (rank : 122)
Query Neighborhood Hits	263	Target Neighborhood Hits	489	Shared Neighborhood Hits	60
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

SH3K1_HUMAN
θ value	1.69304e-06 (rank : 10)	NC score	0.449871 (rank : 7)
Query Neighborhood Hits	263	Target Neighborhood Hits	341	Shared Neighborhood Hits	130
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

DNMBP_HUMAN
θ value	4.92598e-06 (rank : 11)	NC score	0.347030 (rank : 22)
Query Neighborhood Hits	263	Target Neighborhood Hits	413	Shared Neighborhood Hits	119
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SH3K1_MOUSE
θ value	6.43352e-06 (rank : 12)	NC score	0.445146 (rank : 8)
Query Neighborhood Hits	263	Target Neighborhood Hits	332	Shared Neighborhood Hits	130
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

DNMBP_MOUSE
θ value	1.87187e-05 (rank : 13)	NC score	0.338779 (rank : 23)
Query Neighborhood Hits	263	Target Neighborhood Hits	435	Shared Neighborhood Hits	120
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PACN1_HUMAN
θ value	1.87187e-05 (rank : 14)	NC score	0.358176 (rank : 18)
Query Neighborhood Hits	263	Target Neighborhood Hits	320	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	1.87187e-05 (rank : 15)	NC score	0.359564 (rank : 16)
Query Neighborhood Hits	263	Target Neighborhood Hits	283	Shared Neighborhood Hits	118
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

FINC_MOUSE
θ value	2.44474e-05 (rank : 16)	NC score	0.253233 (rank : 68)
Query Neighborhood Hits	263	Target Neighborhood Hits	309	Shared Neighborhood Hits	65
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FGR_HUMAN
θ value	7.1131e-05 (rank : 17)	NC score	0.094642 (rank : 249)
Query Neighborhood Hits	263	Target Neighborhood Hits	1067	Shared Neighborhood Hits	125
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ITSN1_HUMAN
θ value	7.1131e-05 (rank : 18)	NC score	0.244113 (rank : 71)
Query Neighborhood Hits	263	Target Neighborhood Hits	1757	Shared Neighborhood Hits	160
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PTPRD_MOUSE
θ value	7.1131e-05 (rank : 19)	NC score	0.175732 (rank : 117)
Query Neighborhood Hits	263	Target Neighborhood Hits	491	Shared Neighborhood Hits	63
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SH3G1_HUMAN
θ value	9.29e-05 (rank : 20)	NC score	0.375510 (rank : 12)
Query Neighborhood Hits	263	Target Neighborhood Hits	307	Shared Neighborhood Hits	126
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G2_MOUSE
θ value	9.29e-05 (rank : 21)	NC score	0.387226 (rank : 10)
Query Neighborhood Hits	263	Target Neighborhood Hits	319	Shared Neighborhood Hits	126
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

TENR_MOUSE
θ value	9.29e-05 (rank : 22)	NC score	0.154693 (rank : 137)
Query Neighborhood Hits	263	Target Neighborhood Hits	531	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENR_HUMAN
θ value	0.000121331 (rank : 23)	NC score	0.158286 (rank : 132)
Query Neighborhood Hits	263	Target Neighborhood Hits	526	Shared Neighborhood Hits	58
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

FINC_HUMAN
θ value	0.000158464 (rank : 24)	NC score	0.243655 (rank : 75)
Query Neighborhood Hits	263	Target Neighborhood Hits	302	Shared Neighborhood Hits	62
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

SH3G2_HUMAN
θ value	0.00020696 (rank : 25)	NC score	0.384493 (rank : 11)
Query Neighborhood Hits	263	Target Neighborhood Hits	324	Shared Neighborhood Hits	130
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

ABI2_MOUSE
θ value	0.000270298 (rank : 26)	NC score	0.364762 (rank : 15)
Query Neighborhood Hits	263	Target Neighborhood Hits	266	Shared Neighborhood Hits	116
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ITSN1_MOUSE
θ value	0.000270298 (rank : 27)	NC score	0.243915 (rank : 73)
Query Neighborhood Hits	263	Target Neighborhood Hits	1669	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ABI2_HUMAN
θ value	0.00035302 (rank : 28)	NC score	0.359038 (rank : 17)
Query Neighborhood Hits	263	Target Neighborhood Hits	350	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

FNDC3_HUMAN
θ value	0.00035302 (rank : 29)	NC score	0.222036 (rank : 88)
Query Neighborhood Hits	263	Target Neighborhood Hits	196	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

PACN2_HUMAN
θ value	0.00035302 (rank : 30)	NC score	0.348517 (rank : 20)
Query Neighborhood Hits	263	Target Neighborhood Hits	339	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SH3G3_MOUSE
θ value	0.00035302 (rank : 31)	NC score	0.388244 (rank : 9)
Query Neighborhood Hits	263	Target Neighborhood Hits	236	Shared Neighborhood Hits	125
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

EM55_HUMAN
θ value	0.000461057 (rank : 32)	NC score	0.182563 (rank : 112)
Query Neighborhood Hits	263	Target Neighborhood Hits	228	Shared Neighborhood Hits	80
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

ITSN2_MOUSE
θ value	0.000461057 (rank : 33)	NC score	0.244083 (rank : 72)
Query Neighborhood Hits	263	Target Neighborhood Hits	1371	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MILK1_MOUSE
θ value	0.000461057 (rank : 34)	NC score	0.056874 (rank : 446)
Query Neighborhood Hits	263	Target Neighborhood Hits	788	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TENA_MOUSE
θ value	0.000461057 (rank : 35)	NC score	0.116122 (rank : 209)
Query Neighborhood Hits	263	Target Neighborhood Hits	596	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

ITSN2_HUMAN
θ value	0.000602161 (rank : 36)	NC score	0.255005 (rank : 67)
Query Neighborhood Hits	263	Target Neighborhood Hits	1173	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

NEO1_HUMAN
θ value	0.000602161 (rank : 37)	NC score	0.183502 (rank : 110)
Query Neighborhood Hits	263	Target Neighborhood Hits	530	Shared Neighborhood Hits	61
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	0.000602161 (rank : 38)	NC score	0.185534 (rank : 108)
Query Neighborhood Hits	263	Target Neighborhood Hits	523	Shared Neighborhood Hits	61
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

PPIP1_MOUSE
θ value	0.00102713 (rank : 39)	NC score	0.338120 (rank : 24)
Query Neighborhood Hits	263	Target Neighborhood Hits	377	Shared Neighborhood Hits	123
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SH3G3_HUMAN
θ value	0.00102713 (rank : 40)	NC score	0.375042 (rank : 13)
Query Neighborhood Hits	263	Target Neighborhood Hits	222	Shared Neighborhood Hits	124
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

EM55_MOUSE
θ value	0.00134147 (rank : 41)	NC score	0.178020 (rank : 115)
Query Neighborhood Hits	263	Target Neighborhood Hits	221	Shared Neighborhood Hits	78
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

GRB2_HUMAN
θ value	0.00134147 (rank : 42)	NC score	0.327813 (rank : 27)
Query Neighborhood Hits	263	Target Neighborhood Hits	310	Shared Neighborhood Hits	122
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.00134147 (rank : 43)	NC score	0.327965 (rank : 26)
Query Neighborhood Hits	263	Target Neighborhood Hits	312	Shared Neighborhood Hits	122
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

PACN2_MOUSE
θ value	0.00134147 (rank : 44)	NC score	0.332961 (rank : 25)
Query Neighborhood Hits	263	Target Neighborhood Hits	382	Shared Neighborhood Hits	121
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SDK2_HUMAN
θ value	0.00134147 (rank : 45)	NC score	0.194120 (rank : 105)
Query Neighborhood Hits	263	Target Neighborhood Hits	495	Shared Neighborhood Hits	64
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

AHI1_HUMAN
θ value	0.00175202 (rank : 46)	NC score	0.241943 (rank : 78)
Query Neighborhood Hits	263	Target Neighborhood Hits	537	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
θ value	0.00175202 (rank : 47)	NC score	0.243445 (rank : 76)
Query Neighborhood Hits	263	Target Neighborhood Hits	496	Shared Neighborhood Hits	113
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ARHG6_HUMAN
θ value	0.00175202 (rank : 48)	NC score	0.313197 (rank : 39)
Query Neighborhood Hits	263	Target Neighborhood Hits	376	Shared Neighborhood Hits	123
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	0.00175202 (rank : 49)	NC score	0.312148 (rank : 40)
Query Neighborhood Hits	263	Target Neighborhood Hits	394	Shared Neighborhood Hits	128
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

BTK_HUMAN
θ value	0.00175202 (rank : 50)	NC score	0.084219 (rank : 279)
Query Neighborhood Hits	263	Target Neighborhood Hits	1026	Shared Neighborhood Hits	118
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

SH3G1_MOUSE
θ value	0.00175202 (rank : 51)	NC score	0.369148 (rank : 14)
Query Neighborhood Hits	263	Target Neighborhood Hits	291	Shared Neighborhood Hits	126
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

FNDC3_MOUSE
θ value	0.00298849 (rank : 52)	NC score	0.216010 (rank : 93)
Query Neighborhood Hits	263	Target Neighborhood Hits	207	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

MYO1F_HUMAN
θ value	0.00298849 (rank : 53)	NC score	0.149281 (rank : 140)
Query Neighborhood Hits	263	Target Neighborhood Hits	275	Shared Neighborhood Hits	120
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

PPIP1_HUMAN
θ value	0.00298849 (rank : 54)	NC score	0.327755 (rank : 28)
Query Neighborhood Hits	263	Target Neighborhood Hits	389	Shared Neighborhood Hits	119
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

VAV3_HUMAN
θ value	0.00298849 (rank : 55)	NC score	0.241336 (rank : 79)
Query Neighborhood Hits	263	Target Neighborhood Hits	398	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

ARHG7_HUMAN
θ value	0.00390308 (rank : 56)	NC score	0.307433 (rank : 41)
Query Neighborhood Hits	263	Target Neighborhood Hits	347	Shared Neighborhood Hits	124
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

BTK_MOUSE
θ value	0.00390308 (rank : 57)	NC score	0.081021 (rank : 296)
Query Neighborhood Hits	263	Target Neighborhood Hits	1017	Shared Neighborhood Hits	115
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

DSCL1_HUMAN
θ value	0.00390308 (rank : 58)	NC score	0.166391 (rank : 128)
Query Neighborhood Hits	263	Target Neighborhood Hits	589	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

VAV_HUMAN
θ value	0.00390308 (rank : 59)	NC score	0.270346 (rank : 58)
Query Neighborhood Hits	263	Target Neighborhood Hits	452	Shared Neighborhood Hits	118
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	0.00390308 (rank : 60)	NC score	0.271172 (rank : 57)
Query Neighborhood Hits	263	Target Neighborhood Hits	430	Shared Neighborhood Hits	120
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

DCC_HUMAN
θ value	0.00509761 (rank : 61)	NC score	0.176691 (rank : 116)
Query Neighborhood Hits	263	Target Neighborhood Hits	583	Shared Neighborhood Hits	63
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

ROBO1_HUMAN
θ value	0.00509761 (rank : 62)	NC score	0.149152 (rank : 141)
Query Neighborhood Hits	263	Target Neighborhood Hits	529	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

STAM2_MOUSE
θ value	0.00509761 (rank : 63)	NC score	0.317915 (rank : 35)
Query Neighborhood Hits	263	Target Neighborhood Hits	285	Shared Neighborhood Hits	122
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

VAV3_MOUSE
θ value	0.00509761 (rank : 64)	NC score	0.234298 (rank : 84)
Query Neighborhood Hits	263	Target Neighborhood Hits	404	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

GRAP_MOUSE
θ value	0.00665767 (rank : 65)	NC score	0.301847 (rank : 43)
Query Neighborhood Hits	263	Target Neighborhood Hits	309	Shared Neighborhood Hits	123
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

MYO1F_MOUSE
θ value	0.00665767 (rank : 66)	NC score	0.146413 (rank : 147)
Query Neighborhood Hits	263	Target Neighborhood Hits	262	Shared Neighborhood Hits	122
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

ABI1_HUMAN
θ value	0.00869519 (rank : 67)	NC score	0.325755 (rank : 29)
Query Neighborhood Hits	263	Target Neighborhood Hits	257	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

STAM1_HUMAN
θ value	0.00869519 (rank : 68)	NC score	0.318393 (rank : 34)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	124
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	0.00869519 (rank : 69)	NC score	0.317023 (rank : 37)
Query Neighborhood Hits	263	Target Neighborhood Hits	273	Shared Neighborhood Hits	124
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

GRAP_HUMAN
θ value	0.0113563 (rank : 70)	NC score	0.291477 (rank : 48)
Query Neighborhood Hits	263	Target Neighborhood Hits	307	Shared Neighborhood Hits	121
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

NCK1_HUMAN
θ value	0.0113563 (rank : 71)	NC score	0.293897 (rank : 46)
Query Neighborhood Hits	263	Target Neighborhood Hits	312	Shared Neighborhood Hits	115
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	0.0113563 (rank : 72)	NC score	0.290075 (rank : 49)
Query Neighborhood Hits	263	Target Neighborhood Hits	310	Shared Neighborhood Hits	112
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

PACN3_HUMAN
θ value	0.0113563 (rank : 73)	NC score	0.321288 (rank : 31)
Query Neighborhood Hits	263	Target Neighborhood Hits	385	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

SHLB1_MOUSE
θ value	0.0113563 (rank : 74)	NC score	0.224690 (rank : 85)
Query Neighborhood Hits	263	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

VINEX_HUMAN
θ value	0.0148317 (rank : 75)	NC score	0.354750 (rank : 19)
Query Neighborhood Hits	263	Target Neighborhood Hits	270	Shared Neighborhood Hits	119
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

OSTF1_HUMAN
θ value	0.0193708 (rank : 76)	NC score	0.274465 (rank : 54)
Query Neighborhood Hits	263	Target Neighborhood Hits	466	Shared Neighborhood Hits	121
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

SHLB1_HUMAN
θ value	0.0193708 (rank : 77)	NC score	0.220179 (rank : 90)
Query Neighborhood Hits	263	Target Neighborhood Hits	96	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

STAM2_HUMAN
θ value	0.0193708 (rank : 78)	NC score	0.304476 (rank : 42)
Query Neighborhood Hits	263	Target Neighborhood Hits	288	Shared Neighborhood Hits	126
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

PACN3_MOUSE
θ value	0.0252991 (rank : 79)	NC score	0.320580 (rank : 32)
Query Neighborhood Hits	263	Target Neighborhood Hits	380	Shared Neighborhood Hits	119
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

SDK1_HUMAN
θ value	0.0252991 (rank : 80)	NC score	0.183393 (rank : 111)
Query Neighborhood Hits	263	Target Neighborhood Hits	511	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ARHG7_MOUSE
θ value	0.0330416 (rank : 81)	NC score	0.300528 (rank : 44)
Query Neighborhood Hits	263	Target Neighborhood Hits	396	Shared Neighborhood Hits	125
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

M3KL4_HUMAN
θ value	0.0330416 (rank : 82)	NC score	0.094183 (rank : 252)
Query Neighborhood Hits	263	Target Neighborhood Hits	1087	Shared Neighborhood Hits	124
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

OSTF1_MOUSE
θ value	0.0330416 (rank : 83)	NC score	0.264728 (rank : 62)
Query Neighborhood Hits	263	Target Neighborhood Hits	467	Shared Neighborhood Hits	122
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ABI1_MOUSE
θ value	0.0431538 (rank : 84)	NC score	0.323088 (rank : 30)
Query Neighborhood Hits	263	Target Neighborhood Hits	246	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

MPP3_MOUSE
θ value	0.0431538 (rank : 85)	NC score	0.113935 (rank : 213)
Query Neighborhood Hits	263	Target Neighborhood Hits	165	Shared Neighborhood Hits	33
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

SHAN2_MOUSE
θ value	0.0431538 (rank : 86)	NC score	0.169007 (rank : 125)
Query Neighborhood Hits	263	Target Neighborhood Hits	446	Shared Neighborhood Hits	85
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

STAC_MOUSE
θ value	0.0431538 (rank : 87)	NC score	0.268093 (rank : 59)
Query Neighborhood Hits	263	Target Neighborhood Hits	268	Shared Neighborhood Hits	111
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VINEX_MOUSE
θ value	0.0431538 (rank : 88)	NC score	0.347268 (rank : 21)
Query Neighborhood Hits	263	Target Neighborhood Hits	286	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

DCC_MOUSE
θ value	0.0563607 (rank : 89)	NC score	0.171865 (rank : 123)
Query Neighborhood Hits	263	Target Neighborhood Hits	896	Shared Neighborhood Hits	76
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ROBO3_MOUSE
θ value	0.0563607 (rank : 90)	NC score	0.146485 (rank : 146)
Query Neighborhood Hits	263	Target Neighborhood Hits	524	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

USH2A_HUMAN
θ value	0.0563607 (rank : 91)	NC score	0.124962 (rank : 198)
Query Neighborhood Hits	263	Target Neighborhood Hits	600	Shared Neighborhood Hits	62
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

CNTN3_HUMAN
θ value	0.0736092 (rank : 92)	NC score	0.143797 (rank : 152)
Query Neighborhood Hits	263	Target Neighborhood Hits	455	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

MPP2_MOUSE
θ value	0.0736092 (rank : 93)	NC score	0.137193 (rank : 168)
Query Neighborhood Hits	263	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

NCF1_HUMAN
θ value	0.0736092 (rank : 94)	NC score	0.289958 (rank : 50)
Query Neighborhood Hits	263	Target Neighborhood Hits	198	Shared Neighborhood Hits	101
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

SDK2_MOUSE
θ value	0.0736092 (rank : 95)	NC score	0.188815 (rank : 107)
Query Neighborhood Hits	263	Target Neighborhood Hits	480	Shared Neighborhood Hits	64
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TITIN_HUMAN
θ value	0.0736092 (rank : 96)	NC score	0.098319 (rank : 241)
Query Neighborhood Hits	263	Target Neighborhood Hits	2923	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SRC8_HUMAN
θ value	0.0961366 (rank : 97)	NC score	0.299502 (rank : 45)
Query Neighborhood Hits	263	Target Neighborhood Hits	269	Shared Neighborhood Hits	118
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

ABCBB_HUMAN
θ value	0.125558 (rank : 98)	NC score	0.019601 (rank : 558)
Query Neighborhood Hits	263	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

CSKP_HUMAN
θ value	0.125558 (rank : 99)	NC score	0.062611 (rank : 398)
Query Neighborhood Hits	263	Target Neighborhood Hits	1022	Shared Neighborhood Hits	91
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

EFS_MOUSE
θ value	0.125558 (rank : 100)	NC score	0.246906 (rank : 70)
Query Neighborhood Hits	263	Target Neighborhood Hits	389	Shared Neighborhood Hits	107
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

NCF1_MOUSE
θ value	0.125558 (rank : 101)	NC score	0.282104 (rank : 53)
Query Neighborhood Hits	263	Target Neighborhood Hits	198	Shared Neighborhood Hits	106
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NPHP1_HUMAN
θ value	0.125558 (rank : 102)	NC score	0.202579 (rank : 101)
Query Neighborhood Hits	263	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

ROBO1_MOUSE
θ value	0.125558 (rank : 103)	NC score	0.146797 (rank : 145)
Query Neighborhood Hits	263	Target Neighborhood Hits	559	Shared Neighborhood Hits	61
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO2_HUMAN
θ value	0.125558 (rank : 104)	NC score	0.143597 (rank : 153)
Query Neighborhood Hits	263	Target Neighborhood Hits	479	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SRC8_MOUSE
θ value	0.125558 (rank : 105)	NC score	0.293446 (rank : 47)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	118
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

COCA1_MOUSE
θ value	0.163984 (rank : 106)	NC score	0.165834 (rank : 129)
Query Neighborhood Hits	263	Target Neighborhood Hits	467	Shared Neighborhood Hits	66
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

GRAP2_HUMAN
θ value	0.163984 (rank : 107)	NC score	0.282722 (rank : 52)
Query Neighborhood Hits	263	Target Neighborhood Hits	304	Shared Neighborhood Hits	117
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

MYPC3_HUMAN
θ value	0.163984 (rank : 108)	NC score	0.137526 (rank : 167)
Query Neighborhood Hits	263	Target Neighborhood Hits	318	Shared Neighborhood Hits	58
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MYPC3_MOUSE
θ value	0.163984 (rank : 109)	NC score	0.138385 (rank : 166)
Query Neighborhood Hits	263	Target Neighborhood Hits	310	Shared Neighborhood Hits	60
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NRCAM_HUMAN
θ value	0.163984 (rank : 110)	NC score	0.146245 (rank : 148)
Query Neighborhood Hits	263	Target Neighborhood Hits	439	Shared Neighborhood Hits	57
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

RHG26_HUMAN
θ value	0.163984 (rank : 111)	NC score	0.168514 (rank : 126)
Query Neighborhood Hits	263	Target Neighborhood Hits	281	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

ROBO2_MOUSE
θ value	0.163984 (rank : 112)	NC score	0.143476 (rank : 155)
Query Neighborhood Hits	263	Target Neighborhood Hits	504	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SRC_HUMAN
θ value	0.163984 (rank : 113)	NC score	0.085453 (rank : 276)
Query Neighborhood Hits	263	Target Neighborhood Hits	1058	Shared Neighborhood Hits	125
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

TENA_HUMAN
θ value	0.163984 (rank : 114)	NC score	0.107080 (rank : 221)
Query Neighborhood Hits	263	Target Neighborhood Hits	631	Shared Neighborhood Hits	59
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

VAV2_HUMAN
θ value	0.163984 (rank : 115)	NC score	0.237416 (rank : 82)
Query Neighborhood Hits	263	Target Neighborhood Hits	453	Shared Neighborhood Hits	117
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	0.163984 (rank : 116)	NC score	0.239465 (rank : 80)
Query Neighborhood Hits	263	Target Neighborhood Hits	456	Shared Neighborhood Hits	119
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

CNTN4_HUMAN
θ value	0.21417 (rank : 117)	NC score	0.133456 (rank : 176)
Query Neighborhood Hits	263	Target Neighborhood Hits	449	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN4_MOUSE
θ value	0.21417 (rank : 118)	NC score	0.135449 (rank : 172)
Query Neighborhood Hits	263	Target Neighborhood Hits	445	Shared Neighborhood Hits	59
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

MPP2_HUMAN
θ value	0.21417 (rank : 119)	NC score	0.131825 (rank : 181)
Query Neighborhood Hits	263	Target Neighborhood Hits	173	Shared Neighborhood Hits	58
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP3_HUMAN
θ value	0.21417 (rank : 120)	NC score	0.112968 (rank : 215)
Query Neighborhood Hits	263	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

SDK1_MOUSE
θ value	0.21417 (rank : 121)	NC score	0.180526 (rank : 113)
Query Neighborhood Hits	263	Target Neighborhood Hits	495	Shared Neighborhood Hits	62
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SNX9_MOUSE
θ value	0.21417 (rank : 122)	NC score	0.198633 (rank : 103)
Query Neighborhood Hits	263	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

ABCBB_MOUSE
θ value	0.279714 (rank : 123)	NC score	0.018709 (rank : 560)
Query Neighborhood Hits	263	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

COCA1_HUMAN
θ value	0.279714 (rank : 124)	NC score	0.157672 (rank : 133)
Query Neighborhood Hits	263	Target Neighborhood Hits	458	Shared Neighborhood Hits	60
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CRK_HUMAN
θ value	0.279714 (rank : 125)	NC score	0.266572 (rank : 60)
Query Neighborhood Hits	263	Target Neighborhood Hits	308	Shared Neighborhood Hits	120
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	0.279714 (rank : 126)	NC score	0.272846 (rank : 56)
Query Neighborhood Hits	263	Target Neighborhood Hits	314	Shared Neighborhood Hits	120
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

GRAP2_MOUSE
θ value	0.279714 (rank : 127)	NC score	0.286027 (rank : 51)
Query Neighborhood Hits	263	Target Neighborhood Hits	297	Shared Neighborhood Hits	117
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

M3K11_HUMAN
θ value	0.279714 (rank : 128)	NC score	0.089512 (rank : 266)
Query Neighborhood Hits	263	Target Neighborhood Hits	1136	Shared Neighborhood Hits	129
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

TIE2_HUMAN
θ value	0.279714 (rank : 129)	NC score	0.058278 (rank : 432)
Query Neighborhood Hits	263	Target Neighborhood Hits	1192	Shared Neighborhood Hits	74
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

BCAR1_HUMAN
θ value	0.365318 (rank : 130)	NC score	0.223962 (rank : 87)
Query Neighborhood Hits	263	Target Neighborhood Hits	554	Shared Neighborhood Hits	116
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

COEA1_HUMAN
θ value	0.365318 (rank : 131)	NC score	0.129856 (rank : 186)
Query Neighborhood Hits	263	Target Neighborhood Hits	427	Shared Neighborhood Hits	66
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

DDEF1_MOUSE
θ value	0.365318 (rank : 132)	NC score	0.149066 (rank : 142)
Query Neighborhood Hits	263	Target Neighborhood Hits	592	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

PTPRB_HUMAN
θ value	0.365318 (rank : 133)	NC score	0.115782 (rank : 210)
Query Neighborhood Hits	263	Target Neighborhood Hits	242	Shared Neighborhood Hits	49
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

ROBO4_HUMAN
θ value	0.365318 (rank : 134)	NC score	0.133083 (rank : 177)
Query Neighborhood Hits	263	Target Neighborhood Hits	364	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

SNX9_HUMAN
θ value	0.365318 (rank : 135)	NC score	0.213816 (rank : 96)
Query Neighborhood Hits	263	Target Neighborhood Hits	148	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

CSK_HUMAN
θ value	0.47712 (rank : 136)	NC score	0.065854 (rank : 373)
Query Neighborhood Hits	263	Target Neighborhood Hits	1009	Shared Neighborhood Hits	97
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	0.47712 (rank : 137)	NC score	0.065937 (rank : 372)
Query Neighborhood Hits	263	Target Neighborhood Hits	1009	Shared Neighborhood Hits	97
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CT032_HUMAN
θ value	0.47712 (rank : 138)	NC score	0.255680 (rank : 66)
Query Neighborhood Hits	263	Target Neighborhood Hits	235	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DDEF2_HUMAN
θ value	0.47712 (rank : 139)	NC score	0.143850 (rank : 151)
Query Neighborhood Hits	263	Target Neighborhood Hits	599	Shared Neighborhood Hits	107
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

HUCE1_MOUSE
θ value	0.47712 (rank : 140)	NC score	0.036098 (rank : 538)
Query Neighborhood Hits	263	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DB85, Q8BHW3	Gene names
Domain Architecture	No domain graphic available
Description	Cerebral protein 1 homolog.

MPP6_MOUSE
θ value	0.47712 (rank : 141)	NC score	0.139392 (rank : 162)
Query Neighborhood Hits	263	Target Neighborhood Hits	187	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

SHAN1_HUMAN
θ value	0.47712 (rank : 142)	NC score	0.123554 (rank : 203)
Query Neighborhood Hits	263	Target Neighborhood Hits	1041	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SNX7_MOUSE
θ value	0.47712 (rank : 143)	NC score	0.048505 (rank : 523)
Query Neighborhood Hits	263	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CY18	Gene names	Snx7
Domain Architecture
Description	Sorting nexin-7.

ASPP1_MOUSE
θ value	0.62314 (rank : 144)	NC score	0.131791 (rank : 182)
Query Neighborhood Hits	263	Target Neighborhood Hits	1244	Shared Neighborhood Hits	131
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BCAR1_MOUSE
θ value	0.62314 (rank : 145)	NC score	0.224687 (rank : 86)
Query Neighborhood Hits	263	Target Neighborhood Hits	438	Shared Neighborhood Hits	116
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

DDEF2_MOUSE
θ value	0.62314 (rank : 146)	NC score	0.148051 (rank : 144)
Query Neighborhood Hits	263	Target Neighborhood Hits	625	Shared Neighborhood Hits	103
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

EPHAA_HUMAN
θ value	0.62314 (rank : 147)	NC score	0.040939 (rank : 532)
Query Neighborhood Hits	263	Target Neighborhood Hits	960	Shared Neighborhood Hits	59
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

MILK1_HUMAN
θ value	0.62314 (rank : 148)	NC score	0.041739 (rank : 531)
Query Neighborhood Hits	263	Target Neighborhood Hits	427	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MPP6_HUMAN
θ value	0.62314 (rank : 149)	NC score	0.143478 (rank : 154)
Query Neighborhood Hits	263	Target Neighborhood Hits	180	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

SNX7_HUMAN
θ value	0.62314 (rank : 150)	NC score	0.048280 (rank : 524)
Query Neighborhood Hits	263	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UNH6, Q86U82, Q8WVD4, Q96FW9, Q9Y3Z7	Gene names	SNX7
Domain Architecture
Description	Sorting nexin-7.

COKA1_HUMAN
θ value	0.813845 (rank : 151)	NC score	0.123882 (rank : 202)
Query Neighborhood Hits	263	Target Neighborhood Hits	403	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CS029_MOUSE
θ value	0.813845 (rank : 152)	NC score	0.061857 (rank : 406)
Query Neighborhood Hits	263	Target Neighborhood Hits	201	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

EFS_HUMAN
θ value	0.813845 (rank : 153)	NC score	0.235934 (rank : 83)
Query Neighborhood Hits	263	Target Neighborhood Hits	348	Shared Neighborhood Hits	109
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

NCF2_HUMAN
θ value	0.813845 (rank : 154)	NC score	0.314680 (rank : 38)
Query Neighborhood Hits	263	Target Neighborhood Hits	229	Shared Neighborhood Hits	104
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

REST_HUMAN
θ value	0.813845 (rank : 155)	NC score	0.049598 (rank : 522)
Query Neighborhood Hits	263	Target Neighborhood Hits	1605	Shared Neighborhood Hits	58
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SNX18_HUMAN
θ value	0.813845 (rank : 156)	NC score	0.216808 (rank : 92)
Query Neighborhood Hits	263	Target Neighborhood Hits	207	Shared Neighborhood Hits	97
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SPTA1_HUMAN
θ value	0.813845 (rank : 157)	NC score	0.099499 (rank : 236)
Query Neighborhood Hits	263	Target Neighborhood Hits	748	Shared Neighborhood Hits	117
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TTBK1_HUMAN
θ value	0.813845 (rank : 158)	NC score	0.020409 (rank : 555)
Query Neighborhood Hits	263	Target Neighborhood Hits	1058	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

BI2L1_HUMAN
θ value	1.06291 (rank : 159)	NC score	0.095666 (rank : 247)
Query Neighborhood Hits	263	Target Neighborhood Hits	156	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CNTN3_MOUSE
θ value	1.06291 (rank : 160)	NC score	0.139880 (rank : 161)
Query Neighborhood Hits	263	Target Neighborhood Hits	447	Shared Neighborhood Hits	61
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CT075_HUMAN
θ value	1.06291 (rank : 161)	NC score	0.070076 (rank : 349)
Query Neighborhood Hits	263	Target Neighborhood Hits	387	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

LRC45_MOUSE
θ value	1.06291 (rank : 162)	NC score	0.054241 (rank : 469)
Query Neighborhood Hits	263	Target Neighborhood Hits	959	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

NACAM_MOUSE
θ value	1.06291 (rank : 163)	NC score	0.050999 (rank : 512)
Query Neighborhood Hits	263	Target Neighborhood Hits	1866	Shared Neighborhood Hits	73
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SNX18_MOUSE
θ value	1.06291 (rank : 164)	NC score	0.215516 (rank : 94)
Query Neighborhood Hits	263	Target Neighborhood Hits	198	Shared Neighborhood Hits	95
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

STAC_HUMAN
θ value	1.06291 (rank : 165)	NC score	0.273808 (rank : 55)
Query Neighborhood Hits	263	Target Neighborhood Hits	276	Shared Neighborhood Hits	112
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TIE2_MOUSE
θ value	1.06291 (rank : 166)	NC score	0.056714 (rank : 449)
Query Neighborhood Hits	263	Target Neighborhood Hits	1204	Shared Neighborhood Hits	75
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

YES_HUMAN
θ value	1.06291 (rank : 167)	NC score	0.083044 (rank : 285)
Query Neighborhood Hits	263	Target Neighborhood Hits	1059	Shared Neighborhood Hits	123
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	1.06291 (rank : 168)	NC score	0.083453 (rank : 284)
Query Neighborhood Hits	263	Target Neighborhood Hits	1052	Shared Neighborhood Hits	122
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

CASL_MOUSE
θ value	1.38821 (rank : 169)	NC score	0.214201 (rank : 95)
Query Neighborhood Hits	263	Target Neighborhood Hits	225	Shared Neighborhood Hits	110
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CNTN6_MOUSE
θ value	1.38821 (rank : 170)	NC score	0.133975 (rank : 174)
Query Neighborhood Hits	263	Target Neighborhood Hits	429	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

CS029_HUMAN
θ value	1.38821 (rank : 171)	NC score	0.062425 (rank : 401)
Query Neighborhood Hits	263	Target Neighborhood Hits	329	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

FGR_MOUSE
θ value	1.38821 (rank : 172)	NC score	0.085423 (rank : 277)
Query Neighborhood Hits	263	Target Neighborhood Hits	1069	Shared Neighborhood Hits	124
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

L1CAM_HUMAN
θ value	1.38821 (rank : 173)	NC score	0.140310 (rank : 160)
Query Neighborhood Hits	263	Target Neighborhood Hits	457	Shared Neighborhood Hits	62
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

IASPP_MOUSE
θ value	1.81305 (rank : 174)	NC score	0.141510 (rank : 157)
Query Neighborhood Hits	263	Target Neighborhood Hits	1024	Shared Neighborhood Hits	120
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

INCE_HUMAN
θ value	1.81305 (rank : 175)	NC score	0.055559 (rank : 458)
Query Neighborhood Hits	263	Target Neighborhood Hits	978	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

M3K9_HUMAN
θ value	1.81305 (rank : 176)	NC score	0.078098 (rank : 308)
Query Neighborhood Hits	263	Target Neighborhood Hits	1123	Shared Neighborhood Hits	119
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

OPTN_MOUSE
θ value	1.81305 (rank : 177)	NC score	0.043164 (rank : 527)
Query Neighborhood Hits	263	Target Neighborhood Hits	1120	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RRBP1_MOUSE
θ value	1.81305 (rank : 178)	NC score	0.039537 (rank : 535)
Query Neighborhood Hits	263	Target Neighborhood Hits	1650	Shared Neighborhood Hits	58
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SRBS1_HUMAN
θ value	1.81305 (rank : 179)	NC score	0.317486 (rank : 36)
Query Neighborhood Hits	263	Target Neighborhood Hits	396	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	1.81305 (rank : 180)	NC score	0.319178 (rank : 33)
Query Neighborhood Hits	263	Target Neighborhood Hits	409	Shared Neighborhood Hits	124
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CHL1_HUMAN
θ value	2.36792 (rank : 181)	NC score	0.139013 (rank : 164)
Query Neighborhood Hits	263	Target Neighborhood Hits	413	Shared Neighborhood Hits	57
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

COEA1_MOUSE
θ value	2.36792 (rank : 182)	NC score	0.135746 (rank : 171)
Query Neighborhood Hits	263	Target Neighborhood Hits	402	Shared Neighborhood Hits	64
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CSKP_MOUSE
θ value	2.36792 (rank : 183)	NC score	0.057924 (rank : 437)
Query Neighborhood Hits	263	Target Neighborhood Hits	1027	Shared Neighborhood Hits	97
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

IASPP_HUMAN
θ value	2.36792 (rank : 184)	NC score	0.150854 (rank : 138)
Query Neighborhood Hits	263	Target Neighborhood Hits	688	Shared Neighborhood Hits	110
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LRRK2_MOUSE
θ value	2.36792 (rank : 185)	NC score	0.016751 (rank : 563)
Query Neighborhood Hits	263	Target Neighborhood Hits	1359	Shared Neighborhood Hits	25
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

MYPC1_HUMAN
θ value	2.36792 (rank : 186)	NC score	0.122620 (rank : 204)
Query Neighborhood Hits	263	Target Neighborhood Hits	303	Shared Neighborhood Hits	57
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

PDCD7_HUMAN
θ value	2.36792 (rank : 187)	NC score	0.033631 (rank : 540)
Query Neighborhood Hits	263	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

TARA_MOUSE
θ value	2.36792 (rank : 188)	NC score	0.038032 (rank : 536)
Query Neighborhood Hits	263	Target Neighborhood Hits	1133	Shared Neighborhood Hits	49
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRAF3_HUMAN
θ value	2.36792 (rank : 189)	NC score	0.042143 (rank : 530)
Query Neighborhood Hits	263	Target Neighborhood Hits	463	Shared Neighborhood Hits	22
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	2.36792 (rank : 190)	NC score	0.042589 (rank : 528)
Query Neighborhood Hits	263	Target Neighborhood Hits	476	Shared Neighborhood Hits	24
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

ARTN_HUMAN
θ value	3.0926 (rank : 191)	NC score	0.021048 (rank : 553)
Query Neighborhood Hits	263	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

DUS3L_MOUSE
θ value	3.0926 (rank : 192)	NC score	0.016817 (rank : 562)
Query Neighborhood Hits	263	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XI1, Q3TZQ1, Q7TT12	Gene names	Dus3l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

GOG8A_HUMAN
θ value	3.0926 (rank : 193)	NC score	0.053614 (rank : 475)
Query Neighborhood Hits	263	Target Neighborhood Hits	635	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

L1CAM_MOUSE
θ value	3.0926 (rank : 194)	NC score	0.136183 (rank : 170)
Query Neighborhood Hits	263	Target Neighborhood Hits	457	Shared Neighborhood Hits	61
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

MPP4_MOUSE
θ value	3.0926 (rank : 195)	NC score	0.108281 (rank : 219)
Query Neighborhood Hits	263	Target Neighborhood Hits	188	Shared Neighborhood Hits	49
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MYPC2_HUMAN
θ value	3.0926 (rank : 196)	NC score	0.130680 (rank : 183)
Query Neighborhood Hits	263	Target Neighborhood Hits	316	Shared Neighborhood Hits	57
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NCF4_MOUSE
θ value	3.0926 (rank : 197)	NC score	0.263050 (rank : 63)
Query Neighborhood Hits	263	Target Neighborhood Hits	177	Shared Neighborhood Hits	105
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

PDCD7_MOUSE
θ value	3.0926 (rank : 198)	NC score	0.030618 (rank : 544)
Query Neighborhood Hits	263	Target Neighborhood Hits	214	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

TBCD4_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.012521 (rank : 576)
Query Neighborhood Hits	263	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

CASL_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.211233 (rank : 97)
Query Neighborhood Hits	263	Target Neighborhood Hits	259	Shared Neighborhood Hits	111
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

FOXP3_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.007812 (rank : 586)
Query Neighborhood Hits	263	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JB6	Gene names	Foxp3
Domain Architecture
Description	Forkhead box protein P3 (Scurfin).

GAB2_MOUSE
θ value	4.03905 (rank : 202)	NC score	0.015285 (rank : 566)
Query Neighborhood Hits	263	Target Neighborhood Hits	220	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

HDAC7_MOUSE
θ value	4.03905 (rank : 203)	NC score	0.010738 (rank : 578)
Query Neighborhood Hits	263	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

K1967_MOUSE
θ value	4.03905 (rank : 204)	NC score	0.013715 (rank : 573)
Query Neighborhood Hits	263	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

KTN1_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.036654 (rank : 537)
Query Neighborhood Hits	263	Target Neighborhood Hits	1197	Shared Neighborhood Hits	40
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MYO5C_HUMAN
θ value	4.03905 (rank : 206)	NC score	0.030219 (rank : 545)
Query Neighborhood Hits	263	Target Neighborhood Hits	1206	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

SIRT1_MOUSE
θ value	4.03905 (rank : 207)	NC score	0.015979 (rank : 564)
Query Neighborhood Hits	263	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

SNPC4_MOUSE
θ value	4.03905 (rank : 208)	NC score	0.021090 (rank : 552)
Query Neighborhood Hits	263	Target Neighborhood Hits	237	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

ST5_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.009341 (rank : 583)
Query Neighborhood Hits	263	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

AHTF1_MOUSE
θ value	5.27518 (rank : 210)	NC score	0.014538 (rank : 569)
Query Neighborhood Hits	263	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CF182_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.028565 (rank : 549)
Query Neighborhood Hits	263	Target Neighborhood Hits	474	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CO5A2_HUMAN
θ value	5.27518 (rank : 212)	NC score	0.014005 (rank : 572)
Query Neighborhood Hits	263	Target Neighborhood Hits	760	Shared Neighborhood Hits	18
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CP250_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.049958 (rank : 520)
Query Neighborhood Hits	263	Target Neighborhood Hits	1805	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

ELK1_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.005262 (rank : 589)
Query Neighborhood Hits	263	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

GASP1_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.008445 (rank : 585)
Query Neighborhood Hits	263	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JY77, O43168, Q96LA1	Gene names	GPRASP1, GASP, KIAA0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

MUC1_HUMAN
θ value	5.27518 (rank : 216)	NC score	0.026858 (rank : 550)
Query Neighborhood Hits	263	Target Neighborhood Hits	975	Shared Neighborhood Hits	39
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOR2_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.029145 (rank : 547)
Query Neighborhood Hits	263	Target Neighborhood Hits	870	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PITM1_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.013330 (rank : 574)
Query Neighborhood Hits	263	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

REXO1_MOUSE
θ value	5.27518 (rank : 219)	NC score	0.013049 (rank : 575)
Query Neighborhood Hits	263	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

RGS3_MOUSE
θ value	5.27518 (rank : 220)	NC score	0.028644 (rank : 548)
Query Neighborhood Hits	263	Target Neighborhood Hits	1621	Shared Neighborhood Hits	61
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

S3TC2_MOUSE
θ value	5.27518 (rank : 221)	NC score	0.039802 (rank : 534)
Query Neighborhood Hits	263	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

SEM6D_MOUSE
θ value	5.27518 (rank : 222)	NC score	0.003637 (rank : 590)
Query Neighborhood Hits	263	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SRC_MOUSE
θ value	5.27518 (rank : 223)	NC score	0.067595 (rank : 366)
Query Neighborhood Hits	263	Target Neighborhood Hits	1033	Shared Neighborhood Hits	107
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

CAR11_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.042527 (rank : 529)
Query Neighborhood Hits	263	Target Neighborhood Hits	690	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CIZ1_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.017597 (rank : 561)
Query Neighborhood Hits	263	Target Neighborhood Hits	359	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CNKR1_HUMAN
θ value	6.88961 (rank : 226)	NC score	0.014066 (rank : 571)
Query Neighborhood Hits	263	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNTN1_HUMAN
θ value	6.88961 (rank : 227)	NC score	0.129176 (rank : 188)
Query Neighborhood Hits	263	Target Neighborhood Hits	431	Shared Neighborhood Hits	55
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN6_HUMAN
θ value	6.88961 (rank : 228)	NC score	0.130424 (rank : 184)
Query Neighborhood Hits	263	Target Neighborhood Hits	422	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CP250_MOUSE
θ value	6.88961 (rank : 229)	NC score	0.049759 (rank : 521)
Query Neighborhood Hits	263	Target Neighborhood Hits	1583	Shared Neighborhood Hits	58
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DLG2_HUMAN
θ value	6.88961 (rank : 230)	NC score	0.061107 (rank : 412)
Query Neighborhood Hits	263	Target Neighborhood Hits	279	Shared Neighborhood Hits	60
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

FOXP3_HUMAN
θ value	6.88961 (rank : 231)	NC score	0.006561 (rank : 588)
Query Neighborhood Hits	263	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZS1, O60827, Q4ZH51	Gene names	FOXP3, IPEX
Domain Architecture
Description	Forkhead box protein P3 (Scurfin).

GLE1_HUMAN
θ value	6.88961 (rank : 232)	NC score	0.069250 (rank : 356)
Query Neighborhood Hits	263	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

GOGA6_HUMAN
θ value	6.88961 (rank : 233)	NC score	0.044071 (rank : 526)
Query Neighborhood Hits	263	Target Neighborhood Hits	1007	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

K0256_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.020118 (rank : 556)
Query Neighborhood Hits	263	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q93073, Q8N767	Gene names	KIAA0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

K0256_MOUSE
θ value	6.88961 (rank : 235)	NC score	0.019379 (rank : 559)
Query Neighborhood Hits	263	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

KTN1_MOUSE
θ value	6.88961 (rank : 236)	NC score	0.040237 (rank : 533)
Query Neighborhood Hits	263	Target Neighborhood Hits	1324	Shared Neighborhood Hits	45
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYPC2_MOUSE
θ value	6.88961 (rank : 237)	NC score	0.133004 (rank : 179)
Query Neighborhood Hits	263	Target Neighborhood Hits	297	Shared Neighborhood Hits	58
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MZF1_HUMAN
θ value	6.88961 (rank : 238)	NC score	-0.007073 (rank : 592)
Query Neighborhood Hits	263	Target Neighborhood Hits	753	Shared Neighborhood Hits	4
SwissProt Accessions	P28698, Q9NRY0, Q9UBW2	Gene names	MZF1, MZF, ZNF42, ZSCAN6
Domain Architecture
Description	Myeloid zinc finger 1 (MZF-1) (Zinc finger protein 42) (Zinc finger and SCAN domain-containing protein 6).

NEBL_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.193132 (rank : 106)
Query Neighborhood Hits	263	Target Neighborhood Hits	457	Shared Neighborhood Hits	117
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NFIX_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.009718 (rank : 582)
Query Neighborhood Hits	263	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q14938, O60413, Q12859, Q13050, Q13052, Q9UPH1, Q9Y6R8	Gene names	NFIX
Domain Architecture
Description	Nuclear factor 1 X-type (Nuclear factor 1/X) (NF1-X) (NFI-X) (NF-I/X) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIX_MOUSE
θ value	6.88961 (rank : 241)	NC score	0.009742 (rank : 581)
Query Neighborhood Hits	263	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P70257, O08519, P70258, Q64192, Q99L78, Q9R1G2	Gene names	Nfix
Domain Architecture
Description	Nuclear factor 1 X-type (Nuclear factor 1/X) (NF1-X) (NFI-X) (NF-I/X) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PPRB_MOUSE
θ value	6.88961 (rank : 242)	NC score	0.015422 (rank : 565)
Query Neighborhood Hits	263	Target Neighborhood Hits	354	Shared Neighborhood Hits	19
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

REST_MOUSE
θ value	6.88961 (rank : 243)	NC score	0.035791 (rank : 539)
Query Neighborhood Hits	263	Target Neighborhood Hits	1506	Shared Neighborhood Hits	50
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RHG04_HUMAN
θ value	6.88961 (rank : 244)	NC score	0.143046 (rank : 156)
Query Neighborhood Hits	263	Target Neighborhood Hits	307	Shared Neighborhood Hits	111
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

TCAL5_HUMAN
θ value	6.88961 (rank : 245)	NC score	0.007380 (rank : 587)
Query Neighborhood Hits	263	Target Neighborhood Hits	806	Shared Neighborhood Hits	23
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TEX9_MOUSE
θ value	6.88961 (rank : 246)	NC score	0.032602 (rank : 542)
Query Neighborhood Hits	263	Target Neighborhood Hits	581	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

VDP_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.020786 (rank : 554)
Query Neighborhood Hits	263	Target Neighborhood Hits	645	Shared Neighborhood Hits	29
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

ZEP1_HUMAN
θ value	6.88961 (rank : 248)	NC score	-0.001545 (rank : 591)
Query Neighborhood Hits	263	Target Neighborhood Hits	1036	Shared Neighborhood Hits	13
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

AKA12_HUMAN
θ value	8.99809 (rank : 249)	NC score	0.010636 (rank : 579)
Query Neighborhood Hits	263	Target Neighborhood Hits	825	Shared Neighborhood Hits	27
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CBL_MOUSE
θ value	8.99809 (rank : 250)	NC score	0.009007 (rank : 584)
Query Neighborhood Hits	263	Target Neighborhood Hits	426	Shared Neighborhood Hits	16
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBP_MOUSE
θ value	8.99809 (rank : 251)	NC score	0.014089 (rank : 570)
Query Neighborhood Hits	263	Target Neighborhood Hits	1051	Shared Neighborhood Hits	38
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DTNB_MOUSE
θ value	8.99809 (rank : 252)	NC score	0.019746 (rank : 557)
Query Neighborhood Hits	263	Target Neighborhood Hits	263	Shared Neighborhood Hits	19
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

EEA1_MOUSE
θ value	8.99809 (rank : 253)	NC score	0.032199 (rank : 543)
Query Neighborhood Hits	263	Target Neighborhood Hits	1637	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

HDAC5_HUMAN
θ value	8.99809 (rank : 254)	NC score	0.015122 (rank : 568)
Query Neighborhood Hits	263	Target Neighborhood Hits	353	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

MYBPH_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.096488 (rank : 245)
Query Neighborhood Hits	263	Target Neighborhood Hits	256	Shared Neighborhood Hits	51
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYH3_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.032625 (rank : 541)
Query Neighborhood Hits	263	Target Neighborhood Hits	1660	Shared Neighborhood Hits	63
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH6_MOUSE
θ value	8.99809 (rank : 257)	NC score	0.029724 (rank : 546)
Query Neighborhood Hits	263	Target Neighborhood Hits	1501	Shared Neighborhood Hits	54
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NOC2L_HUMAN
θ value	8.99809 (rank : 258)	NC score	0.009794 (rank : 580)
Query Neighborhood Hits	263	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

ROS_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.047911 (rank : 525)
Query Neighborhood Hits	263	Target Neighborhood Hits	907	Shared Neighborhood Hits	71
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SFR16_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.015181 (rank : 567)
Query Neighborhood Hits	263	Target Neighborhood Hits	178	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N2M8, O96026, Q6UW71, Q96DX2	Gene names	SFRS16, SWAP2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2).

TR240_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.012298 (rank : 577)
Query Neighborhood Hits	263	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

USH2A_MOUSE
θ value	8.99809 (rank : 262)	NC score	0.117011 (rank : 208)
Query Neighborhood Hits	263	Target Neighborhood Hits	626	Shared Neighborhood Hits	64
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

YETS2_HUMAN
θ value	8.99809 (rank : 263)	NC score	0.025766 (rank : 551)
Query Neighborhood Hits	263	Target Neighborhood Hits	212	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ABI3_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.243810 (rank : 74)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.238520 (rank : 81)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABL1_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.054026 (rank : 470)
Query Neighborhood Hits	263	Target Neighborhood Hits	1220	Shared Neighborhood Hits	95
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.053889 (rank : 472)
Query Neighborhood Hits	263	Target Neighborhood Hits	1178	Shared Neighborhood Hits	92
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.051019 (rank : 511)
Query Neighborhood Hits	263	Target Neighborhood Hits	1045	Shared Neighborhood Hits	82
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

AMPH_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.089498 (rank : 267)
Query Neighborhood Hits	263	Target Neighborhood Hits	455	Shared Neighborhood Hits	68
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.078035 (rank : 311)
Query Neighborhood Hits	263	Target Neighborhood Hits	291	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANKF1_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.053126 (rank : 486)
Query Neighborhood Hits	263	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANM2_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.121409 (rank : 206)
Query Neighborhood Hits	263	Target Neighborhood Hits	175	Shared Neighborhood Hits	90
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.111639 (rank : 217)
Query Neighborhood Hits	263	Target Neighborhood Hits	175	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARHG1_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.058041 (rank : 435)
Query Neighborhood Hits	263	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.055679 (rank : 455)
Query Neighborhood Hits	263	Target Neighborhood Hits	266	Shared Neighborhood Hits	25
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.055647 (rank : 456)
Query Neighborhood Hits	263	Target Neighborhood Hits	142	Shared Neighborhood Hits	23
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG3_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.081721 (rank : 291)
Query Neighborhood Hits	263	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.081641 (rank : 292)
Query Neighborhood Hits	263	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG4_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.170951 (rank : 124)
Query Neighborhood Hits	263	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.144961 (rank : 150)
Query Neighborhood Hits	263	Target Neighborhood Hits	185	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG5_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.102970 (rank : 229)
Query Neighborhood Hits	263	Target Neighborhood Hits	172	Shared Neighborhood Hits	68
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG8_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.070908 (rank : 343)
Query Neighborhood Hits	263	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.077763 (rank : 312)
Query Neighborhood Hits	263	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHG9_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.173440 (rank : 119)
Query Neighborhood Hits	263	Target Neighborhood Hits	235	Shared Neighborhood Hits	104
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.173850 (rank : 118)
Query Neighborhood Hits	263	Target Neighborhood Hits	234	Shared Neighborhood Hits	104
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHGA_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.064163 (rank : 387)
Query Neighborhood Hits	263	Target Neighborhood Hits	187	Shared Neighborhood Hits	17
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.067031 (rank : 368)
Query Neighborhood Hits	263	Target Neighborhood Hits	125	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.055837 (rank : 453)
Query Neighborhood Hits	263	Target Neighborhood Hits	375	Shared Neighborhood Hits	27
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.057593 (rank : 442)
Query Neighborhood Hits	263	Target Neighborhood Hits	351	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.057886 (rank : 439)
Query Neighborhood Hits	263	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.067843 (rank : 363)
Query Neighborhood Hits	263	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.080251 (rank : 298)
Query Neighborhood Hits	263	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ASPP1_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.125355 (rank : 196)
Query Neighborhood Hits	263	Target Neighborhood Hits	956	Shared Neighborhood Hits	127
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.129214 (rank : 187)
Query Neighborhood Hits	263	Target Neighborhood Hits	1156	Shared Neighborhood Hits	129
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

AZI1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.052216 (rank : 495)
Query Neighborhood Hits	263	Target Neighborhood Hits	1000	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BAIP2_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.062534 (rank : 400)
Query Neighborhood Hits	263	Target Neighborhood Hits	192	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.064362 (rank : 386)
Query Neighborhood Hits	263	Target Neighborhood Hits	185	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BASI_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.061212 (rank : 410)
Query Neighborhood Hits	263	Target Neighborhood Hits	211	Shared Neighborhood Hits	33
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BASI_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.060737 (rank : 416)
Query Neighborhood Hits	263	Target Neighborhood Hits	238	Shared Neighborhood Hits	31
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BI2L1_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.073055 (rank : 324)
Query Neighborhood Hits	263	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BIN1_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.071161 (rank : 342)
Query Neighborhood Hits	263	Target Neighborhood Hits	335	Shared Neighborhood Hits	58
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.072334 (rank : 329)
Query Neighborhood Hits	263	Target Neighborhood Hits	283	Shared Neighborhood Hits	62
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BLK_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.055561 (rank : 457)
Query Neighborhood Hits	263	Target Neighborhood Hits	994	Shared Neighborhood Hits	89
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.056820 (rank : 447)
Query Neighborhood Hits	263	Target Neighborhood Hits	992	Shared Neighborhood Hits	82
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BOC_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.114101 (rank : 212)
Query Neighborhood Hits	263	Target Neighborhood Hits	543	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

BOC_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.112129 (rank : 216)
Query Neighborhood Hits	263	Target Neighborhood Hits	433	Shared Neighborhood Hits	57
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CAR10_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.054930 (rank : 466)
Query Neighborhood Hits	263	Target Neighborhood Hits	569	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

CD22_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.056875 (rank : 445)
Query Neighborhood Hits	263	Target Neighborhood Hits	365	Shared Neighborhood Hits	37
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD22_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.061698 (rank : 408)
Query Neighborhood Hits	263	Target Neighborhood Hits	331	Shared Neighborhood Hits	35
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD45_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.061074 (rank : 413)
Query Neighborhood Hits	263	Target Neighborhood Hits	243	Shared Neighborhood Hits	39
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.053529 (rank : 478)
Query Neighborhood Hits	263	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CDON_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.113343 (rank : 214)
Query Neighborhood Hits	263	Target Neighborhood Hits	412	Shared Neighborhood Hits	53
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CDON_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.114360 (rank : 211)
Query Neighborhood Hits	263	Target Neighborhood Hits	410	Shared Neighborhood Hits	53
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CEA20_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.050981 (rank : 513)
Query Neighborhood Hits	263	Target Neighborhood Hits	251	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.051771 (rank : 502)
Query Neighborhood Hits	263	Target Neighborhood Hits	326	Shared Neighborhood Hits	36
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CEAM5_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.054397 (rank : 468)
Query Neighborhood Hits	263	Target Neighborhood Hits	343	Shared Neighborhood Hits	37
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

CHL1_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.128490 (rank : 191)
Query Neighborhood Hits	263	Target Neighborhood Hits	402	Shared Neighborhood Hits	56
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CI094_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.068370 (rank : 359)
Query Neighborhood Hits	263	Target Neighborhood Hits	310	Shared Neighborhood Hits	37
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CIP4_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.087946 (rank : 269)
Query Neighborhood Hits	263	Target Neighborhood Hits	374	Shared Neighborhood Hits	58
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CNTN1_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.127499 (rank : 192)
Query Neighborhood Hits	263	Target Neighborhood Hits	422	Shared Neighborhood Hits	55
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.127258 (rank : 193)
Query Neighborhood Hits	263	Target Neighborhood Hits	440	Shared Neighborhood Hits	58
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.126230 (rank : 194)
Query Neighborhood Hits	263	Target Neighborhood Hits	450	Shared Neighborhood Hits	57
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN5_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.124555 (rank : 200)
Query Neighborhood Hits	263	Target Neighborhood Hits	446	Shared Neighborhood Hits	57
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN5_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.125550 (rank : 195)
Query Neighborhood Hits	263	Target Neighborhood Hits	434	Shared Neighborhood Hits	56
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CO7A1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.104095 (rank : 227)
Query Neighborhood Hits	263	Target Neighborhood Hits	807	Shared Neighborhood Hits	61
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CRKL_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.256162 (rank : 65)
Query Neighborhood Hits	263	Target Neighborhood Hits	313	Shared Neighborhood Hits	119
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.251838 (rank : 69)
Query Neighborhood Hits	263	Target Neighborhood Hits	307	Shared Neighborhood Hits	117
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CSF3R_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.074068 (rank : 321)
Query Neighborhood Hits	263	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CSF3R_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.058286 (rank : 430)
Query Neighborhood Hits	263	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CT116_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.053016 (rank : 487)
Query Neighborhood Hits	263	Target Neighborhood Hits	268	Shared Neighborhood Hits	16
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

DAPP1_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.053428 (rank : 480)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.053666 (rank : 474)
Query Neighborhood Hits	263	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DBNL_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.208114 (rank : 98)
Query Neighborhood Hits	263	Target Neighborhood Hits	244	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.206025 (rank : 99)
Query Neighborhood Hits	263	Target Neighborhood Hits	306	Shared Neighborhood Hits	109
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DLG1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.053593 (rank : 476)
Query Neighborhood Hits	263	Target Neighborhood Hits	290	Shared Neighborhood Hits	56
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.052858 (rank : 490)
Query Neighborhood Hits	263	Target Neighborhood Hits	285	Shared Neighborhood Hits	61
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG2_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.058493 (rank : 429)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	58
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.055730 (rank : 454)
Query Neighborhood Hits	263	Target Neighborhood Hits	269	Shared Neighborhood Hits	57
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.055176 (rank : 462)
Query Neighborhood Hits	263	Target Neighborhood Hits	274	Shared Neighborhood Hits	57
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG4_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.050939 (rank : 514)
Query Neighborhood Hits	263	Target Neighborhood Hits	286	Shared Neighborhood Hits	54
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DOCK1_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.072146 (rank : 334)
Query Neighborhood Hits	263	Target Neighborhood Hits	191	Shared Neighborhood Hits	83
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DSCAM_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.145732 (rank : 149)
Query Neighborhood Hits	263	Target Neighborhood Hits	524	Shared Neighborhood Hits	61
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DUET_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.067521 (rank : 367)
Query Neighborhood Hits	263	Target Neighborhood Hits	1220	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ECT2_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.062605 (rank : 399)
Query Neighborhood Hits	263	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.065394 (rank : 379)
Query Neighborhood Hits	263	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EPS8_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.086489 (rank : 273)
Query Neighborhood Hits	263	Target Neighborhood Hits	151	Shared Neighborhood Hits	75
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.086066 (rank : 275)
Query Neighborhood Hits	263	Target Neighborhood Hits	157	Shared Neighborhood Hits	79
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ES8L1_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.079268 (rank : 305)
Query Neighborhood Hits	263	Target Neighborhood Hits	162	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L1_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.081448 (rank : 294)
Query Neighborhood Hits	263	Target Neighborhood Hits	143	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L2_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.103461 (rank : 228)
Query Neighborhood Hits	263	Target Neighborhood Hits	193	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.105722 (rank : 223)
Query Neighborhood Hits	263	Target Neighborhood Hits	169	Shared Neighborhood Hits	81
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L3_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.108541 (rank : 218)
Query Neighborhood Hits	263	Target Neighborhood Hits	206	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ES8L3_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.130283 (rank : 185)
Query Neighborhood Hits	263	Target Neighborhood Hits	168	Shared Neighborhood Hits	92
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

F107B_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.055853 (rank : 452)
Query Neighborhood Hits	263	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

F107B_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.055101 (rank : 463)
Query Neighborhood Hits	263	Target Neighborhood Hits	126	Shared Neighborhood Hits	13
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

FCRL2_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.057870 (rank : 441)
Query Neighborhood Hits	263	Target Neighborhood Hits	251	Shared Neighborhood Hits	31
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.056881 (rank : 444)
Query Neighborhood Hits	263	Target Neighborhood Hits	267	Shared Neighborhood Hits	31
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FGRL1_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.091354 (rank : 260)
Query Neighborhood Hits	263	Target Neighborhood Hits	335	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.089683 (rank : 265)
Query Neighborhood Hits	263	Target Neighborhood Hits	325	Shared Neighborhood Hits	38
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FNBP2_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.099560 (rank : 235)
Query Neighborhood Hits	263	Target Neighborhood Hits	432	Shared Neighborhood Hits	101
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FRK_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.059361 (rank : 424)
Query Neighborhood Hits	263	Target Neighborhood Hits	1058	Shared Neighborhood Hits	115
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FSTL4_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.069199 (rank : 357)
Query Neighborhood Hits	263	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.071202 (rank : 341)
Query Neighborhood Hits	263	Target Neighborhood Hits	333	Shared Neighborhood Hits	37
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.071414 (rank : 338)
Query Neighborhood Hits	263	Target Neighborhood Hits	347	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.071471 (rank : 337)
Query Neighborhood Hits	263	Target Neighborhood Hits	355	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FYN_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.081580 (rank : 293)
Query Neighborhood Hits	263	Target Neighborhood Hits	1078	Shared Neighborhood Hits	123
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.082961 (rank : 286)
Query Neighborhood Hits	263	Target Neighborhood Hits	1073	Shared Neighborhood Hits	123
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GLE1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.066986 (rank : 369)
Query Neighborhood Hits	263	Target Neighborhood Hits	504	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

GNRP_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.051103 (rank : 509)
Query Neighborhood Hits	263	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

HCFC2_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.062937 (rank : 396)
Query Neighborhood Hits	263	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HCK_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.063831 (rank : 389)
Query Neighborhood Hits	263	Target Neighborhood Hits	1035	Shared Neighborhood Hits	109
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.064493 (rank : 384)
Query Neighborhood Hits	263	Target Neighborhood Hits	1029	Shared Neighborhood Hits	108
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HCLS1_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.265394 (rank : 61)
Query Neighborhood Hits	263	Target Neighborhood Hits	358	Shared Neighborhood Hits	114
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.262106 (rank : 64)
Query Neighborhood Hits	263	Target Neighborhood Hits	329	Shared Neighborhood Hits	113
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HMCN1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.062324 (rank : 403)
Query Neighborhood Hits	263	Target Neighborhood Hits	983	Shared Neighborhood Hits	42
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

I12R1_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.053572 (rank : 477)
Query Neighborhood Hits	263	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I12R1_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.050024 (rank : 518)
Query Neighborhood Hits	263	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

I12R2_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.086944 (rank : 272)
Query Neighborhood Hits	263	Target Neighborhood Hits	163	Shared Neighborhood Hits	46
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.083640 (rank : 283)
Query Neighborhood Hits	263	Target Neighborhood Hits	143	Shared Neighborhood Hits	44
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IBP7_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.066932 (rank : 370)
Query Neighborhood Hits	263	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.074091 (rank : 320)
Query Neighborhood Hits	263	Target Neighborhood Hits	230	Shared Neighborhood Hits	37
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ICAM5_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.065779 (rank : 375)
Query Neighborhood Hits	263	Target Neighborhood Hits	276	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

ICAM5_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.068258 (rank : 360)
Query Neighborhood Hits	263	Target Neighborhood Hits	308	Shared Neighborhood Hits	36
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IGS4B_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.053190 (rank : 485)
Query Neighborhood Hits	263	Target Neighborhood Hits	305	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

IGS4B_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.052947 (rank : 488)
Query Neighborhood Hits	263	Target Neighborhood Hits	328	Shared Neighborhood Hits	33
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IL6RB_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.091807 (rank : 256)
Query Neighborhood Hits	263	Target Neighborhood Hits	181	Shared Neighborhood Hits	46
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.092139 (rank : 254)
Query Neighborhood Hits	263	Target Neighborhood Hits	168	Shared Neighborhood Hits	49
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

INCE_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.050597 (rank : 517)
Query Neighborhood Hits	263	Target Neighborhood Hits	903	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

ITB4_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.100519 (rank : 231)
Query Neighborhood Hits	263	Target Neighborhood Hits	458	Shared Neighborhood Hits	56
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

JAM1_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.065791 (rank : 374)
Query Neighborhood Hits	263	Target Neighborhood Hits	294	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM1_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.065052 (rank : 382)
Query Neighborhood Hits	263	Target Neighborhood Hits	287	Shared Neighborhood Hits	36
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAM2_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.062124 (rank : 404)
Query Neighborhood Hits	263	Target Neighborhood Hits	304	Shared Neighborhood Hits	37
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM2_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.057453 (rank : 443)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM3_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.074615 (rank : 318)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAM3_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.069414 (rank : 354)
Query Neighborhood Hits	263	Target Neighborhood Hits	286	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JIP1_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.050601 (rank : 516)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP2_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.055342 (rank : 460)
Query Neighborhood Hits	263	Target Neighborhood Hits	288	Shared Neighborhood Hits	52
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K0552_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.052015 (rank : 500)
Query Neighborhood Hits	263	Target Neighborhood Hits	442	Shared Neighborhood Hits	27
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

KALM_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.083689 (rank : 282)
Query Neighborhood Hits	263	Target Neighborhood Hits	114	Shared Neighborhood Hits	34
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KAZD1_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.079864 (rank : 300)
Query Neighborhood Hits	263	Target Neighborhood Hits	248	Shared Neighborhood Hits	37
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.082073 (rank : 289)
Query Neighborhood Hits	263	Target Neighborhood Hits	281	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KGUA_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.058973 (rank : 427)
Query Neighborhood Hits	263	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.059621 (rank : 421)
Query Neighborhood Hits	263	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KIRR1_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.063483 (rank : 392)
Query Neighborhood Hits	263	Target Neighborhood Hits	401	Shared Neighborhood Hits	36
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR1_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.061735 (rank : 407)
Query Neighborhood Hits	263	Target Neighborhood Hits	403	Shared Neighborhood Hits	36
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR2_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.073861 (rank : 322)
Query Neighborhood Hits	263	Target Neighborhood Hits	321	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

KIRR2_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.072390 (rank : 328)
Query Neighborhood Hits	263	Target Neighborhood Hits	326	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KIRR3_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.063978 (rank : 388)
Query Neighborhood Hits	263	Target Neighborhood Hits	302	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

KIRR3_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.062749 (rank : 397)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

LASP1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.203719 (rank : 100)
Query Neighborhood Hits	263	Target Neighborhood Hits	293	Shared Neighborhood Hits	101
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.202091 (rank : 102)
Query Neighborhood Hits	263	Target Neighborhood Hits	297	Shared Neighborhood Hits	101
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LBC_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.053194 (rank : 483)
Query Neighborhood Hits	263	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LCK_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.053428 (rank : 481)
Query Neighborhood Hits	263	Target Neighborhood Hits	987	Shared Neighborhood Hits	83
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.052699 (rank : 492)
Query Neighborhood Hits	263	Target Neighborhood Hits	981	Shared Neighborhood Hits	83
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LIFR_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.090295 (rank : 263)
Query Neighborhood Hits	263	Target Neighborhood Hits	130	Shared Neighborhood Hits	41
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.090866 (rank : 262)
Query Neighborhood Hits	263	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

LNK_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.053936 (rank : 471)
Query Neighborhood Hits	263	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LRIG1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.058990 (rank : 426)
Query Neighborhood Hits	263	Target Neighborhood Hits	654	Shared Neighborhood Hits	40
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.058792 (rank : 428)
Query Neighborhood Hits	263	Target Neighborhood Hits	627	Shared Neighborhood Hits	39
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.059371 (rank : 423)
Query Neighborhood Hits	263	Target Neighborhood Hits	595	Shared Neighborhood Hits	40
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.059137 (rank : 425)
Query Neighborhood Hits	263	Target Neighborhood Hits	586	Shared Neighborhood Hits	40
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.057905 (rank : 438)
Query Neighborhood Hits	263	Target Neighborhood Hits	601	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.058284 (rank : 431)
Query Neighborhood Hits	263	Target Neighborhood Hits	611	Shared Neighborhood Hits	40
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LSAMP_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.071308 (rank : 339)
Query Neighborhood Hits	263	Target Neighborhood Hits	347	Shared Neighborhood Hits	37
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.071878 (rank : 335)
Query Neighborhood Hits	263	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LU_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.065184 (rank : 381)
Query Neighborhood Hits	263	Target Neighborhood Hits	283	Shared Neighborhood Hits	37
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LYN_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.060195 (rank : 420)
Query Neighborhood Hits	263	Target Neighborhood Hits	1022	Shared Neighborhood Hits	101
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.061915 (rank : 405)
Query Neighborhood Hits	263	Target Neighborhood Hits	1023	Shared Neighborhood Hits	101
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LZTS2_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.055423 (rank : 459)
Query Neighborhood Hits	263	Target Neighborhood Hits	423	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

M3K10_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.072210 (rank : 332)
Query Neighborhood Hits	263	Target Neighborhood Hits	1071	Shared Neighborhood Hits	118
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MAG_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.072173 (rank : 333)
Query Neighborhood Hits	263	Target Neighborhood Hits	278	Shared Neighborhood Hits	37
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.072265 (rank : 330)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	37
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MALT1_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.084129 (rank : 280)
Query Neighborhood Hits	263	Target Neighborhood Hits	236	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MAMC1_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.080200 (rank : 299)
Query Neighborhood Hits	263	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.080534 (rank : 297)
Query Neighborhood Hits	263	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MARCS_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.060583 (rank : 418)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MCF2L_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.072622 (rank : 327)
Query Neighborhood Hits	263	Target Neighborhood Hits	255	Shared Neighborhood Hits	37
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.061165 (rank : 411)
Query Neighborhood Hits	263	Target Neighborhood Hits	166	Shared Neighborhood Hits	22
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MDGA1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.078744 (rank : 306)
Query Neighborhood Hits	263	Target Neighborhood Hits	358	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MERTK_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.055049 (rank : 464)
Query Neighborhood Hits	263	Target Neighborhood Hits	988	Shared Neighborhood Hits	63
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.052058 (rank : 496)
Query Neighborhood Hits	263	Target Neighborhood Hits	974	Shared Neighborhood Hits	61
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MFA3L_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.057882 (rank : 440)
Query Neighborhood Hits	263	Target Neighborhood Hits	230	Shared Neighborhood Hits	37
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MFA3L_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.051774 (rank : 501)
Query Neighborhood Hits	263	Target Neighborhood Hits	214	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MPP4_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.082097 (rank : 288)
Query Neighborhood Hits	263	Target Neighborhood Hits	205	Shared Neighborhood Hits	45
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP5_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.099157 (rank : 238)
Query Neighborhood Hits	263	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.098656 (rank : 240)
Query Neighborhood Hits	263	Target Neighborhood Hits	226	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MUC18_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.070351 (rank : 348)
Query Neighborhood Hits	263	Target Neighborhood Hits	275	Shared Neighborhood Hits	36
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

MUC18_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.065295 (rank : 380)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

MUSK_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.061000 (rank : 414)
Query Neighborhood Hits	263	Target Neighborhood Hits	1074	Shared Neighborhood Hits	57
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.061269 (rank : 409)
Query Neighborhood Hits	263	Target Neighborhood Hits	1057	Shared Neighborhood Hits	57
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MYBPH_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.097588 (rank : 243)
Query Neighborhood Hits	263	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYLK_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.052025 (rank : 499)
Query Neighborhood Hits	263	Target Neighborhood Hits	1328	Shared Neighborhood Hits	68
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.052814 (rank : 491)
Query Neighborhood Hits	263	Target Neighborhood Hits	1489	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYO1E_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.121637 (rank : 205)
Query Neighborhood Hits	263	Target Neighborhood Hits	293	Shared Neighborhood Hits	119
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYOM1_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.148986 (rank : 143)
Query Neighborhood Hits	263	Target Neighborhood Hits	405	Shared Neighborhood Hits	62
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

MYOM1_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.140730 (rank : 158)
Query Neighborhood Hits	263	Target Neighborhood Hits	415	Shared Neighborhood Hits	60
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MYOM2_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.139300 (rank : 163)
Query Neighborhood Hits	263	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

MYOTI_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.089341 (rank : 268)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.090122 (rank : 264)
Query Neighborhood Hits	263	Target Neighborhood Hits	297	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYPN_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.092034 (rank : 255)
Query Neighborhood Hits	263	Target Neighborhood Hits	418	Shared Neighborhood Hits	43
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPN_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.091014 (rank : 261)
Query Neighborhood Hits	263	Target Neighborhood Hits	421	Shared Neighborhood Hits	44
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NCA11_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.097918 (rank : 242)
Query Neighborhood Hits	263	Target Neighborhood Hits	443	Shared Neighborhood Hits	51
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA11_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.099665 (rank : 234)
Query Neighborhood Hits	263	Target Neighborhood Hits	661	Shared Neighborhood Hits	62
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.094422 (rank : 251)
Query Neighborhood Hits	263	Target Neighborhood Hits	437	Shared Neighborhood Hits	49
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCA12_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.096033 (rank : 246)
Query Neighborhood Hits	263	Target Neighborhood Hits	399	Shared Neighborhood Hits	49
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

NCAM2_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.105191 (rank : 224)
Query Neighborhood Hits	263	Target Neighborhood Hits	441	Shared Neighborhood Hits	55
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

NCAM2_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.108159 (rank : 220)
Query Neighborhood Hits	263	Target Neighborhood Hits	472	Shared Neighborhood Hits	55
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NCF4_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.243385 (rank : 77)
Query Neighborhood Hits	263	Target Neighborhood Hits	161	Shared Neighborhood Hits	93
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NEBU_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.154846 (rank : 136)
Query Neighborhood Hits	263	Target Neighborhood Hits	420	Shared Neighborhood Hits	107
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NEGR1_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.072767 (rank : 326)
Query Neighborhood Hits	263	Target Neighborhood Hits	346	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.071268 (rank : 340)
Query Neighborhood Hits	263	Target Neighborhood Hits	349	Shared Neighborhood Hits	37
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

NFASC_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.133028 (rank : 178)
Query Neighborhood Hits	263	Target Neighborhood Hits	497	Shared Neighborhood Hits	59
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NFASC_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.128595 (rank : 190)
Query Neighborhood Hits	263	Target Neighborhood Hits	475	Shared Neighborhood Hits	61
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

NGEF_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.094475 (rank : 250)
Query Neighborhood Hits	263	Target Neighborhood Hits	166	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.097087 (rank : 244)
Query Neighborhood Hits	263	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NOXO1_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.099108 (rank : 239)
Query Neighborhood Hits	263	Target Neighborhood Hits	100	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.150334 (rank : 139)
Query Neighborhood Hits	263	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHN_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.106539 (rank : 222)
Query Neighborhood Hits	263	Target Neighborhood Hits	362	Shared Neighborhood Hits	56
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NPHN_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.100281 (rank : 232)
Query Neighborhood Hits	263	Target Neighborhood Hits	370	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NPHP1_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.197911 (rank : 104)
Query Neighborhood Hits	263	Target Neighborhood Hits	267	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NPTN_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.070457 (rank : 347)
Query Neighborhood Hits	263	Target Neighborhood Hits	212	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NPTN_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.069988 (rank : 350)
Query Neighborhood Hits	263	Target Neighborhood Hits	216	Shared Neighborhood Hits	36
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRCAM_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.136379 (rank : 169)
Query Neighborhood Hits	263	Target Neighborhood Hits	432	Shared Neighborhood Hits	55
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

NRG2_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.069820 (rank : 352)
Query Neighborhood Hits	263	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.053193 (rank : 484)
Query Neighborhood Hits	263	Target Neighborhood Hits	392	Shared Neighborhood Hits	39
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NTRI_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.065665 (rank : 377)
Query Neighborhood Hits	263	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NTRI_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.066600 (rank : 371)
Query Neighborhood Hits	263	Target Neighborhood Hits	342	Shared Neighborhood Hits	37
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

OBSCN_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.063275 (rank : 394)
Query Neighborhood Hits	263	Target Neighborhood Hits	1931	Shared Neighborhood Hits	98
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OBSL1_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.102786 (rank : 230)
Query Neighborhood Hits	263	Target Neighborhood Hits	354	Shared Neighborhood Hits	38
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

OPCM_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.070509 (rank : 346)
Query Neighborhood Hits	263	Target Neighborhood Hits	332	Shared Neighborhood Hits	37
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

P55G_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.052047 (rank : 498)
Query Neighborhood Hits	263	Target Neighborhood Hits	451	Shared Neighborhood Hits	46
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.050724 (rank : 515)
Query Neighborhood Hits	263	Target Neighborhood Hits	401	Shared Neighborhood Hits	44
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85A_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.075010 (rank : 315)
Query Neighborhood Hits	263	Target Neighborhood Hits	479	Shared Neighborhood Hits	69
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.078059 (rank : 310)
Query Neighborhood Hits	263	Target Neighborhood Hits	435	Shared Neighborhood Hits	72
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.062939 (rank : 395)
Query Neighborhood Hits	263	Target Neighborhood Hits	543	Shared Neighborhood Hits	61
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.060538 (rank : 419)
Query Neighborhood Hits	263	Target Neighborhood Hits	519	Shared Neighborhood Hits	60
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PEX13_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.172245 (rank : 121)
Query Neighborhood Hits	263	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.173358 (rank : 120)
Query Neighborhood Hits	263	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PGBM_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.064393 (rank : 385)
Query Neighborhood Hits	263	Target Neighborhood Hits	1113	Shared Neighborhood Hits	49
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.063709 (rank : 390)
Query Neighborhood Hits	263	Target Neighborhood Hits	1073	Shared Neighborhood Hits	50
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PKHG1_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.084991 (rank : 278)
Query Neighborhood Hits	263	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PLCG1_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.162658 (rank : 131)
Query Neighborhood Hits	263	Target Neighborhood Hits	293	Shared Neighborhood Hits	102
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.168187 (rank : 127)
Query Neighborhood Hits	263	Target Neighborhood Hits	314	Shared Neighborhood Hits	107
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.165776 (rank : 130)
Query Neighborhood Hits	263	Target Neighborhood Hits	280	Shared Neighborhood Hits	99
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PPIP2_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.079682 (rank : 302)
Query Neighborhood Hits	263	Target Neighborhood Hits	254	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

PPIP2_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.073708 (rank : 323)
Query Neighborhood Hits	263	Target Neighborhood Hits	308	Shared Neighborhood Hits	25
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PREX1_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.078091 (rank : 309)
Query Neighborhood Hits	263	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PTK6_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.052267 (rank : 494)
Query Neighborhood Hits	263	Target Neighborhood Hits	1020	Shared Neighborhood Hits	106
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.053264 (rank : 482)
Query Neighborhood Hits	263	Target Neighborhood Hits	1026	Shared Neighborhood Hits	103
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTK7_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.064997 (rank : 383)
Query Neighborhood Hits	263	Target Neighborhood Hits	1103	Shared Neighborhood Hits	58
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

PTN11_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.068177 (rank : 361)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.068176 (rank : 362)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN6_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.065474 (rank : 378)
Query Neighborhood Hits	263	Target Neighborhood Hits	234	Shared Neighborhood Hits	32
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.065668 (rank : 376)
Query Neighborhood Hits	263	Target Neighborhood Hits	225	Shared Neighborhood Hits	33
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRA_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.051340 (rank : 504)
Query Neighborhood Hits	263	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.051311 (rank : 505)
Query Neighborhood Hits	263	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.051141 (rank : 508)
Query Neighborhood Hits	263	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.051305 (rank : 506)
Query Neighborhood Hits	263	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.079495 (rank : 303)
Query Neighborhood Hits	263	Target Neighborhood Hits	207	Shared Neighborhood Hits	36
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.081133 (rank : 295)
Query Neighborhood Hits	263	Target Neighborhood Hits	188	Shared Neighborhood Hits	39
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.074992 (rank : 316)
Query Neighborhood Hits	263	Target Neighborhood Hits	228	Shared Neighborhood Hits	48
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.075832 (rank : 314)
Query Neighborhood Hits	263	Target Neighborhood Hits	223	Shared Neighborhood Hits	48
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.091540 (rank : 259)
Query Neighborhood Hits	263	Target Neighborhood Hits	244	Shared Neighborhood Hits	53
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.091541 (rank : 258)
Query Neighborhood Hits	263	Target Neighborhood Hits	238	Shared Neighborhood Hits	53
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRO_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.067768 (rank : 364)
Query Neighborhood Hits	263	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRT_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.087512 (rank : 271)
Query Neighborhood Hits	263	Target Neighborhood Hits	217	Shared Neighborhood Hits	48
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.087866 (rank : 270)
Query Neighborhood Hits	263	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.079708 (rank : 301)
Query Neighborhood Hits	263	Target Neighborhood Hits	237	Shared Neighborhood Hits	50
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.084117 (rank : 281)
Query Neighborhood Hits	263	Target Neighborhood Hits	179	Shared Neighborhood Hits	39
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PUNC_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.132770 (rank : 180)
Query Neighborhood Hits	263	Target Neighborhood Hits	449	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PUNC_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.133525 (rank : 175)
Query Neighborhood Hits	263	Target Neighborhood Hits	501	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RAGE_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.071597 (rank : 336)
Query Neighborhood Hits	263	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RAGE_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.069289 (rank : 355)
Query Neighborhood Hits	263	Target Neighborhood Hits	295	Shared Neighborhood Hits	37
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RASA1_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.058136 (rank : 433)
Query Neighborhood Hits	263	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RGNEF_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.058042 (rank : 434)
Query Neighborhood Hits	263	Target Neighborhood Hits	641	Shared Neighborhood Hits	43
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RILP_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.053433 (rank : 479)
Query Neighborhood Hits	263	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

ROBO3_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.134689 (rank : 173)
Query Neighborhood Hits	263	Target Neighborhood Hits	570	Shared Neighborhood Hits	61
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

ROBO4_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.117694 (rank : 207)
Query Neighborhood Hits	263	Target Neighborhood Hits	358	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

RUSC1_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.140335 (rank : 159)
Query Neighborhood Hits	263	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC1_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.128900 (rank : 189)
Query Neighborhood Hits	263	Target Neighborhood Hits	206	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SH21B_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.052050 (rank : 497)
Query Neighborhood Hits	263	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SHC3_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.051531 (rank : 503)
Query Neighborhood Hits	263	Target Neighborhood Hits	151	Shared Neighborhood Hits	29
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHLB2_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.155202 (rank : 135)
Query Neighborhood Hits	263	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.155204 (rank : 134)
Query Neighborhood Hits	263	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SLAP1_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.063417 (rank : 393)
Query Neighborhood Hits	263	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.060997 (rank : 415)
Query Neighborhood Hits	263	Target Neighborhood Hits	117	Shared Neighborhood Hits	22
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.070621 (rank : 345)
Query Neighborhood Hits	263	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.070804 (rank : 344)
Query Neighborhood Hits	263	Target Neighborhood Hits	136	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SLY_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.069487 (rank : 353)
Query Neighborhood Hits	263	Target Neighborhood Hits	81	Shared Neighborhood Hits	46
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.078348 (rank : 307)
Query Neighborhood Hits	263	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SN_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.059471 (rank : 422)
Query Neighborhood Hits	263	Target Neighborhood Hits	434	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

SN_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.062367 (rank : 402)
Query Neighborhood Hits	263	Target Neighborhood Hits	416	Shared Neighborhood Hits	38
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

SORL_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.069837 (rank : 351)
Query Neighborhood Hits	263	Target Neighborhood Hits	440	Shared Neighborhood Hits	55
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.063698 (rank : 391)
Query Neighborhood Hits	263	Target Neighborhood Hits	439	Shared Neighborhood Hits	52
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPEG_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.056717 (rank : 448)
Query Neighborhood Hits	263	Target Neighborhood Hits	1762	Shared Neighborhood Hits	91
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.054934 (rank : 465)
Query Neighborhood Hits	263	Target Neighborhood Hits	1959	Shared Neighborhood Hits	89
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPN90_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.095418 (rank : 248)
Query Neighborhood Hits	263	Target Neighborhood Hits	157	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPN90_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.082344 (rank : 287)
Query Neighborhood Hits	263	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPTA1_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.093499 (rank : 253)
Query Neighborhood Hits	263	Target Neighborhood Hits	675	Shared Neighborhood Hits	114
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.105117 (rank : 225)
Query Neighborhood Hits	263	Target Neighborhood Hits	888	Shared Neighborhood Hits	130
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRGP1_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.105077 (rank : 226)
Query Neighborhood Hits	263	Target Neighborhood Hits	390	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.124252 (rank : 201)
Query Neighborhood Hits	263	Target Neighborhood Hits	331	Shared Neighborhood Hits	99
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.124588 (rank : 199)
Query Neighborhood Hits	263	Target Neighborhood Hits	324	Shared Neighborhood Hits	101
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

STAC3_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.221727 (rank : 89)
Query Neighborhood Hits	263	Target Neighborhood Hits	228	Shared Neighborhood Hits	96
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.219808 (rank : 91)
Query Neighborhood Hits	263	Target Neighborhood Hits	232	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STS1_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.072817 (rank : 325)
Query Neighborhood Hits	263	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS1_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.072218 (rank : 331)
Query Neighborhood Hits	263	Target Neighborhood Hits	104	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS2_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.099230 (rank : 237)
Query Neighborhood Hits	263	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

TARSH_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.081807 (rank : 290)
Query Neighborhood Hits	263	Target Neighborhood Hits	768	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TCGAP_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.086115 (rank : 274)
Query Neighborhood Hits	263	Target Neighborhood Hits	872	Shared Neighborhood Hits	107
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.091769 (rank : 257)
Query Neighborhood Hits	263	Target Neighborhood Hits	409	Shared Neighborhood Hits	93
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TEC_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.052681 (rank : 493)
Query Neighborhood Hits	263	Target Neighborhood Hits	1006	Shared Neighborhood Hits	94
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.051243 (rank : 507)
Query Neighborhood Hits	263	Target Neighborhood Hits	1006	Shared Neighborhood Hits	91
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TENN_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.125086 (rank : 197)
Query Neighborhood Hits	263	Target Neighborhood Hits	453	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.138934 (rank : 165)
Query Neighborhood Hits	263	Target Neighborhood Hits	484	Shared Neighborhood Hits	60
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENX_HUMAN
θ value	θ > 10 (rank : 576)	NC score	0.099976 (rank : 233)
Query Neighborhood Hits	263	Target Neighborhood Hits	789	Shared Neighborhood Hits	64
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TIAM1_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.077633 (rank : 313)
Query Neighborhood Hits	263	Target Neighborhood Hits	225	Shared Neighborhood Hits	21
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.079326 (rank : 304)
Query Neighborhood Hits	263	Target Neighborhood Hits	205	Shared Neighborhood Hits	23
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TMIGD_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.074784 (rank : 317)
Query Neighborhood Hits	263	Target Neighborhood Hits	240	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.074227 (rank : 319)
Query Neighborhood Hits	263	Target Neighborhood Hits	234	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TRIO_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.052874 (rank : 489)
Query Neighborhood Hits	263	Target Neighborhood Hits	1580	Shared Neighborhood Hits	114
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TXK_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.050022 (rank : 519)
Query Neighborhood Hits	263	Target Neighborhood Hits	971	Shared Neighborhood Hits	86
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.054770 (rank : 467)
Query Neighborhood Hits	263	Target Neighborhood Hits	980	Shared Neighborhood Hits	93
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TYRO3_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.057952 (rank : 436)
Query Neighborhood Hits	263	Target Neighborhood Hits	995	Shared Neighborhood Hits	66
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.056118 (rank : 450)
Query Neighborhood Hits	263	Target Neighborhood Hits	1007	Shared Neighborhood Hits	68
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

UFO_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.053834 (rank : 473)
Query Neighborhood Hits	263	Target Neighborhood Hits	981	Shared Neighborhood Hits	65
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UFO_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.055179 (rank : 461)
Query Neighborhood Hits	263	Target Neighborhood Hits	988	Shared Neighborhood Hits	72
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

VCAM1_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.067731 (rank : 365)
Query Neighborhood Hits	263	Target Neighborhood Hits	352	Shared Neighborhood Hits	38
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

VCAM1_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.068714 (rank : 358)
Query Neighborhood Hits	263	Target Neighborhood Hits	320	Shared Neighborhood Hits	37
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VSIG2_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.060693 (rank : 417)
Query Neighborhood Hits	263	Target Neighborhood Hits	321	Shared Neighborhood Hits	36
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG2_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.056088 (rank : 451)
Query Neighborhood Hits	263	Target Neighborhood Hits	316	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

XE7_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.051051 (rank : 510)
Query Neighborhood Hits	263	Target Neighborhood Hits	738	Shared Neighborhood Hits	36
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

Hits sorted by NC score

RIMB2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	263	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
NC score	0.970108 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	263	Target Neighborhood Hits	246	Shared Neighborhood Hits	172
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB1_HUMAN
NC score	0.550850 (rank : 3)	θ value	4.32305e-111 (rank : 3)
Query Neighborhood Hits	263	Target Neighborhood Hits	1479	Shared Neighborhood Hits	170
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
NC score	0.484317 (rank : 4)	θ value	5.84277e-108 (rank : 4)
Query Neighborhood Hits	263	Target Neighborhood Hits	1376	Shared Neighborhood Hits	164
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CD2AP_MOUSE
NC score	0.472489 (rank : 5)	θ value	2.79066e-09 (rank : 5)
Query Neighborhood Hits	263	Target Neighborhood Hits	336	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2AP_HUMAN
NC score	0.465959 (rank : 6)	θ value	3.08544e-08 (rank : 6)
Query Neighborhood Hits	263	Target Neighborhood Hits	315	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

SH3K1_HUMAN
NC score	0.449871 (rank : 7)	θ value	1.69304e-06 (rank : 10)
Query Neighborhood Hits	263	Target Neighborhood Hits	341	Shared Neighborhood Hits	130
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
NC score	0.445146 (rank : 8)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	263	Target Neighborhood Hits	332	Shared Neighborhood Hits	130
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SH3G3_MOUSE
NC score	0.388244 (rank : 9)	θ value	0.00035302 (rank : 31)
Query Neighborhood Hits	263	Target Neighborhood Hits	236	Shared Neighborhood Hits	125
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3G2_MOUSE
NC score	0.387226 (rank : 10)	θ value	9.29e-05 (rank : 21)
Query Neighborhood Hits	263	Target Neighborhood Hits	319	Shared Neighborhood Hits	126
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G2_HUMAN
NC score	0.384493 (rank : 11)	θ value	0.00020696 (rank : 25)
Query Neighborhood Hits	263	Target Neighborhood Hits	324	Shared Neighborhood Hits	130
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G1_HUMAN
NC score	0.375510 (rank : 12)	θ value	9.29e-05 (rank : 20)
Query Neighborhood Hits	263	Target Neighborhood Hits	307	Shared Neighborhood Hits	126
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G3_HUMAN
NC score	0.375042 (rank : 13)	θ value	0.00102713 (rank : 40)
Query Neighborhood Hits	263	Target Neighborhood Hits	222	Shared Neighborhood Hits	124
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G1_MOUSE
NC score	0.369148 (rank : 14)	θ value	0.00175202 (rank : 51)
Query Neighborhood Hits	263	Target Neighborhood Hits	291	Shared Neighborhood Hits	126
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

ABI2_MOUSE
NC score	0.364762 (rank : 15)	θ value	0.000270298 (rank : 26)
Query Neighborhood Hits	263	Target Neighborhood Hits	266	Shared Neighborhood Hits	116
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

PACN1_MOUSE
NC score	0.359564 (rank : 16)	θ value	1.87187e-05 (rank : 15)
Query Neighborhood Hits	263	Target Neighborhood Hits	283	Shared Neighborhood Hits	118
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

ABI2_HUMAN
NC score	0.359038 (rank : 17)	θ value	0.00035302 (rank : 28)
Query Neighborhood Hits	263	Target Neighborhood Hits	350	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

PACN1_HUMAN
NC score	0.358176 (rank : 18)	θ value	1.87187e-05 (rank : 14)
Query Neighborhood Hits	263	Target Neighborhood Hits	320	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

VINEX_HUMAN
NC score	0.354750 (rank : 19)	θ value	0.0148317 (rank : 75)
Query Neighborhood Hits	263	Target Neighborhood Hits	270	Shared Neighborhood Hits	119
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

PACN2_HUMAN
NC score	0.348517 (rank : 20)	θ value	0.00035302 (rank : 30)
Query Neighborhood Hits	263	Target Neighborhood Hits	339	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

VINEX_MOUSE
NC score	0.347268 (rank : 21)	θ value	0.0431538 (rank : 88)
Query Neighborhood Hits	263	Target Neighborhood Hits	286	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

DNMBP_HUMAN
NC score	0.347030 (rank : 22)	θ value	4.92598e-06 (rank : 11)
Query Neighborhood Hits	263	Target Neighborhood Hits	413	Shared Neighborhood Hits	119
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
NC score	0.338779 (rank : 23)	θ value	1.87187e-05 (rank : 13)
Query Neighborhood Hits	263	Target Neighborhood Hits	435	Shared Neighborhood Hits	120
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PPIP1_MOUSE
NC score	0.338120 (rank : 24)	θ value	0.00102713 (rank : 39)
Query Neighborhood Hits	263	Target Neighborhood Hits	377	Shared Neighborhood Hits	123
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PACN2_MOUSE
NC score	0.332961 (rank : 25)	θ value	0.00134147 (rank : 44)
Query Neighborhood Hits	263	Target Neighborhood Hits	382	Shared Neighborhood Hits	121
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

GRB2_MOUSE
NC score	0.327965 (rank : 26)	θ value	0.00134147 (rank : 43)
Query Neighborhood Hits	263	Target Neighborhood Hits	312	Shared Neighborhood Hits	122
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRB2_HUMAN
NC score	0.327813 (rank : 27)	θ value	0.00134147 (rank : 42)
Query Neighborhood Hits	263	Target Neighborhood Hits	310	Shared Neighborhood Hits	122
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

PPIP1_HUMAN
NC score	0.327755 (rank : 28)	θ value	0.00298849 (rank : 54)
Query Neighborhood Hits	263	Target Neighborhood Hits	389	Shared Neighborhood Hits	119
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

ABI1_HUMAN
NC score	0.325755 (rank : 29)	θ value	0.00869519 (rank : 67)
Query Neighborhood Hits	263	Target Neighborhood Hits	257	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
NC score	0.323088 (rank : 30)	θ value	0.0431538 (rank : 84)
Query Neighborhood Hits	263	Target Neighborhood Hits	246	Shared Neighborhood Hits	115
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

PACN3_HUMAN
NC score	0.321288 (rank : 31)	θ value	0.0113563 (rank : 73)
Query Neighborhood Hits	263	Target Neighborhood Hits	385	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
NC score	0.320580 (rank : 32)	θ value	0.0252991 (rank : 79)
Query Neighborhood Hits	263	Target Neighborhood Hits	380	Shared Neighborhood Hits	119
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

SRBS1_MOUSE
NC score	0.319178 (rank : 33)	θ value	1.81305 (rank : 180)
Query Neighborhood Hits	263	Target Neighborhood Hits	409	Shared Neighborhood Hits	124
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAM1_HUMAN
NC score	0.318393 (rank : 34)	θ value	0.00869519 (rank : 68)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	124
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
NC score	0.317915 (rank : 35)	θ value	0.00509761 (rank : 63)
Query Neighborhood Hits	263	Target Neighborhood Hits	285	Shared Neighborhood Hits	122
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SRBS1_HUMAN
NC score	0.317486 (rank : 36)	θ value	1.81305 (rank : 179)
Query Neighborhood Hits	263	Target Neighborhood Hits	396	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAM1_MOUSE
NC score	0.317023 (rank : 37)	θ value	0.00869519 (rank : 69)
Query Neighborhood Hits	263	Target Neighborhood Hits	273	Shared Neighborhood Hits	124
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

NCF2_HUMAN
NC score	0.314680 (rank : 38)	θ value	0.813845 (rank : 154)
Query Neighborhood Hits	263	Target Neighborhood Hits	229	Shared Neighborhood Hits	104
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

ARHG6_HUMAN
NC score	0.313197 (rank : 39)	θ value	0.00175202 (rank : 48)
Query Neighborhood Hits	263	Target Neighborhood Hits	376	Shared Neighborhood Hits	123
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
NC score	0.312148 (rank : 40)	θ value	0.00175202 (rank : 49)
Query Neighborhood Hits	263	Target Neighborhood Hits	394	Shared Neighborhood Hits	128
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_HUMAN
NC score	0.307433 (rank : 41)	θ value	0.00390308 (rank : 56)
Query Neighborhood Hits	263	Target Neighborhood Hits	347	Shared Neighborhood Hits	124
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

STAM2_HUMAN
NC score	0.304476 (rank : 42)	θ value	0.0193708 (rank : 78)
Query Neighborhood Hits	263	Target Neighborhood Hits	288	Shared Neighborhood Hits	126
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

GRAP_MOUSE
NC score	0.301847 (rank : 43)	θ value	0.00665767 (rank : 65)
Query Neighborhood Hits	263	Target Neighborhood Hits	309	Shared Neighborhood Hits	123
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ARHG7_MOUSE
NC score	0.300528 (rank : 44)	θ value	0.0330416 (rank : 81)
Query Neighborhood Hits	263	Target Neighborhood Hits	396	Shared Neighborhood Hits	125
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

SRC8_HUMAN
NC score	0.299502 (rank : 45)	θ value	0.0961366 (rank : 97)
Query Neighborhood Hits	263	Target Neighborhood Hits	269	Shared Neighborhood Hits	118
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

NCK1_HUMAN
NC score	0.293897 (rank : 46)	θ value	0.0113563 (rank : 71)
Query Neighborhood Hits	263	Target Neighborhood Hits	312	Shared Neighborhood Hits	115
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

SRC8_MOUSE
NC score	0.293446 (rank : 47)	θ value	0.125558 (rank : 105)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	118
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

GRAP_HUMAN
NC score	0.291477 (rank : 48)	θ value	0.0113563 (rank : 70)
Query Neighborhood Hits	263	Target Neighborhood Hits	307	Shared Neighborhood Hits	121
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

NCK2_HUMAN
NC score	0.290075 (rank : 49)	θ value	0.0113563 (rank : 72)
Query Neighborhood Hits	263	Target Neighborhood Hits	310	Shared Neighborhood Hits	112
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NCF1_HUMAN
NC score	0.289958 (rank : 50)	θ value	0.0736092 (rank : 94)
Query Neighborhood Hits	263	Target Neighborhood Hits	198	Shared Neighborhood Hits	101
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

GRAP2_MOUSE
NC score	0.286027 (rank : 51)	θ value	0.279714 (rank : 127)
Query Neighborhood Hits	263	Target Neighborhood Hits	297	Shared Neighborhood Hits	117
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP2_HUMAN
NC score	0.282722 (rank : 52)	θ value	0.163984 (rank : 107)
Query Neighborhood Hits	263	Target Neighborhood Hits	304	Shared Neighborhood Hits	117
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

NCF1_MOUSE
NC score	0.282104 (rank : 53)	θ value	0.125558 (rank : 101)
Query Neighborhood Hits	263	Target Neighborhood Hits	198	Shared Neighborhood Hits	106
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

OSTF1_HUMAN
NC score	0.274465 (rank : 54)	θ value	0.0193708 (rank : 76)
Query Neighborhood Hits	263	Target Neighborhood Hits	466	Shared Neighborhood Hits	121
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

STAC_HUMAN
NC score	0.273808 (rank : 55)	θ value	1.06291 (rank : 165)
Query Neighborhood Hits	263	Target Neighborhood Hits	276	Shared Neighborhood Hits	112
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CRK_MOUSE
NC score	0.272846 (rank : 56)	θ value	0.279714 (rank : 126)
Query Neighborhood Hits	263	Target Neighborhood Hits	314	Shared Neighborhood Hits	120
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

VAV_MOUSE
NC score	0.271172 (rank : 57)	θ value	0.00390308 (rank : 60)
Query Neighborhood Hits	263	Target Neighborhood Hits	430	Shared Neighborhood Hits	120
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VAV_HUMAN
NC score	0.270346 (rank : 58)	θ value	0.00390308 (rank : 59)
Query Neighborhood Hits	263	Target Neighborhood Hits	452	Shared Neighborhood Hits	118
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

STAC_MOUSE
NC score	0.268093 (rank : 59)	θ value	0.0431538 (rank : 87)
Query Neighborhood Hits	263	Target Neighborhood Hits	268	Shared Neighborhood Hits	111
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CRK_HUMAN
NC score	0.266572 (rank : 60)	θ value	0.279714 (rank : 125)
Query Neighborhood Hits	263	Target Neighborhood Hits	308	Shared Neighborhood Hits	120
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

HCLS1_HUMAN
NC score	0.265394 (rank : 61)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	263	Target Neighborhood Hits	358	Shared Neighborhood Hits	114
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

OSTF1_MOUSE
NC score	0.264728 (rank : 62)	θ value	0.0330416 (rank : 83)
Query Neighborhood Hits	263	Target Neighborhood Hits	467	Shared Neighborhood Hits	122
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

NCF4_MOUSE
NC score	0.263050 (rank : 63)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	263	Target Neighborhood Hits	177	Shared Neighborhood Hits	105
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

HCLS1_MOUSE
NC score	0.262106 (rank : 64)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	263	Target Neighborhood Hits	329	Shared Neighborhood Hits	113
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

CRKL_HUMAN
NC score	0.256162 (rank : 65)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	263	Target Neighborhood Hits	313	Shared Neighborhood Hits	119
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CT032_HUMAN
NC score	0.255680 (rank : 66)	θ value	0.47712 (rank : 138)
Query Neighborhood Hits	263	Target Neighborhood Hits	235	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

ITSN2_HUMAN
NC score	0.255005 (rank : 67)	θ value	0.000602161 (rank : 36)
Query Neighborhood Hits	263	Target Neighborhood Hits	1173	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

FINC_MOUSE
NC score	0.253233 (rank : 68)	θ value	2.44474e-05 (rank : 16)
Query Neighborhood Hits	263	Target Neighborhood Hits	309	Shared Neighborhood Hits	65
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

CRKL_MOUSE
NC score	0.251838 (rank : 69)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	263	Target Neighborhood Hits	307	Shared Neighborhood Hits	117
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

EFS_MOUSE
NC score	0.246906 (rank : 70)	θ value	0.125558 (rank : 100)
Query Neighborhood Hits	263	Target Neighborhood Hits	389	Shared Neighborhood Hits	107
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ITSN1_HUMAN
NC score	0.244113 (rank : 71)	θ value	7.1131e-05 (rank : 18)
Query Neighborhood Hits	263	Target Neighborhood Hits	1757	Shared Neighborhood Hits	160
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_MOUSE
NC score	0.244083 (rank : 72)	θ value	0.000461057 (rank : 33)
Query Neighborhood Hits	263	Target Neighborhood Hits	1371	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITSN1_MOUSE
NC score	0.243915 (rank : 73)	θ value	0.000270298 (rank : 27)
Query Neighborhood Hits	263	Target Neighborhood Hits	1669	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ABI3_HUMAN
NC score	0.243810 (rank : 74)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

FINC_HUMAN
NC score	0.243655 (rank : 75)	θ value	0.000158464 (rank : 24)
Query Neighborhood Hits	263	Target Neighborhood Hits	302	Shared Neighborhood Hits	62
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

AHI1_MOUSE
NC score	0.243445 (rank : 76)	θ value	0.00175202 (rank : 47)
Query Neighborhood Hits	263	Target Neighborhood Hits	496	Shared Neighborhood Hits	113
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

NCF4_HUMAN
NC score	0.243385 (rank : 77)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	263	Target Neighborhood Hits	161	Shared Neighborhood Hits	93
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

AHI1_HUMAN
NC score	0.241943 (rank : 78)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	263	Target Neighborhood Hits	537	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

VAV3_HUMAN
NC score	0.241336 (rank : 79)	θ value	0.00298849 (rank : 55)
Query Neighborhood Hits	263	Target Neighborhood Hits	398	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV2_MOUSE
NC score	0.239465 (rank : 80)	θ value	0.163984 (rank : 116)
Query Neighborhood Hits	263	Target Neighborhood Hits	456	Shared Neighborhood Hits	119
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ABI3_MOUSE
NC score	0.238520 (rank : 81)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

VAV2_HUMAN
NC score	0.237416 (rank : 82)	θ value	0.163984 (rank : 115)
Query Neighborhood Hits	263	Target Neighborhood Hits	453	Shared Neighborhood Hits	117
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

EFS_HUMAN
NC score	0.235934 (rank : 83)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	263	Target Neighborhood Hits	348	Shared Neighborhood Hits	109
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

VAV3_MOUSE
NC score	0.234298 (rank : 84)	θ value	0.00509761 (rank : 64)
Query Neighborhood Hits	263	Target Neighborhood Hits	404	Shared Neighborhood Hits	109
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

SHLB1_MOUSE
NC score	0.224690 (rank : 85)	θ value	0.0113563 (rank : 74)
Query Neighborhood Hits	263	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

BCAR1_MOUSE
NC score	0.224687 (rank : 86)	θ value	0.62314 (rank : 145)
Query Neighborhood Hits	263	Target Neighborhood Hits	438	Shared Neighborhood Hits	116
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_HUMAN
NC score	0.223962 (rank : 87)	θ value	0.365318 (rank : 130)
Query Neighborhood Hits	263	Target Neighborhood Hits	554	Shared Neighborhood Hits	116
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

FNDC3_HUMAN
NC score	0.222036 (rank : 88)	θ value	0.00035302 (rank : 29)
Query Neighborhood Hits	263	Target Neighborhood Hits	196	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

STAC3_HUMAN
NC score	0.221727 (rank : 89)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	263	Target Neighborhood Hits	228	Shared Neighborhood Hits	96
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

SHLB1_HUMAN
NC score	0.220179 (rank : 90)	θ value	0.0193708 (rank : 77)
Query Neighborhood Hits	263	Target Neighborhood Hits	96	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

STAC3_MOUSE
NC score	0.219808 (rank : 91)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	263	Target Neighborhood Hits	232	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

SNX18_HUMAN
NC score	0.216808 (rank : 92)	θ value	0.813845 (rank : 156)
Query Neighborhood Hits	263	Target Neighborhood Hits	207	Shared Neighborhood Hits	97
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

FNDC3_MOUSE
NC score	0.216010 (rank : 93)	θ value	0.00298849 (rank : 52)
Query Neighborhood Hits	263	Target Neighborhood Hits	207	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

SNX18_MOUSE
NC score	0.215516 (rank : 94)	θ value	1.06291 (rank : 164)
Query Neighborhood Hits	263	Target Neighborhood Hits	198	Shared Neighborhood Hits	95
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

CASL_MOUSE
NC score	0.214201 (rank : 95)	θ value	1.38821 (rank : 169)
Query Neighborhood Hits	263	Target Neighborhood Hits	225	Shared Neighborhood Hits	110
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

SNX9_HUMAN
NC score	0.213816 (rank : 96)	θ value	0.365318 (rank : 135)
Query Neighborhood Hits	263	Target Neighborhood Hits	148	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

CASL_HUMAN
NC score	0.211233 (rank : 97)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	263	Target Neighborhood Hits	259	Shared Neighborhood Hits	111
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

DBNL_HUMAN
NC score	0.208114 (rank : 98)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	263	Target Neighborhood Hits	244	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
NC score	0.206025 (rank : 99)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	263	Target Neighborhood Hits	306	Shared Neighborhood Hits	109
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

LASP1_HUMAN
NC score	0.203719 (rank : 100)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	263	Target Neighborhood Hits	293	Shared Neighborhood Hits	101
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

NPHP1_HUMAN
NC score	0.202579 (rank : 101)	θ value	0.125558 (rank : 102)
Query Neighborhood Hits	263	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

LASP1_MOUSE
NC score	0.202091 (rank : 102)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	263	Target Neighborhood Hits	297	Shared Neighborhood Hits	101
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

SNX9_MOUSE
NC score	0.198633 (rank : 103)	θ value	0.21417 (rank : 122)
Query Neighborhood Hits	263	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

NPHP1_MOUSE
NC score	0.197911 (rank : 104)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	263	Target Neighborhood Hits	267	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

SDK2_HUMAN
NC score	0.194120 (rank : 105)	θ value	0.00134147 (rank : 45)
Query Neighborhood Hits	263	Target Neighborhood Hits	495	Shared Neighborhood Hits	64
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NEBL_HUMAN
NC score	0.193132 (rank : 106)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	263	Target Neighborhood Hits	457	Shared Neighborhood Hits	117
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

SDK2_MOUSE
NC score	0.188815 (rank : 107)	θ value	0.0736092 (rank : 95)
Query Neighborhood Hits	263	Target Neighborhood Hits	480	Shared Neighborhood Hits	64
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NEO1_MOUSE
NC score	0.185534 (rank : 108)	θ value	0.000602161 (rank : 38)
Query Neighborhood Hits	263	Target Neighborhood Hits	523	Shared Neighborhood Hits	61
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

PTPRS_HUMAN
NC score	0.184127 (rank : 109)	θ value	2.61198e-07 (rank : 8)
Query Neighborhood Hits	263	Target Neighborhood Hits	472	Shared Neighborhood Hits	63
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

NEO1_HUMAN
NC score	0.183502 (rank : 110)	θ value	0.000602161 (rank : 37)
Query Neighborhood Hits	263	Target Neighborhood Hits	530	Shared Neighborhood Hits	61
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

SDK1_HUMAN
NC score	0.183393 (rank : 111)	θ value	0.0252991 (rank : 80)
Query Neighborhood Hits	263	Target Neighborhood Hits	511	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

EM55_HUMAN
NC score	0.182563 (rank : 112)	θ value	0.000461057 (rank : 32)
Query Neighborhood Hits	263	Target Neighborhood Hits	228	Shared Neighborhood Hits	80
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

SDK1_MOUSE
NC score	0.180526 (rank : 113)	θ value	0.21417 (rank : 121)
Query Neighborhood Hits	263	Target Neighborhood Hits	495	Shared Neighborhood Hits	62
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

PTPRD_HUMAN
NC score	0.180501 (rank : 114)	θ value	2.61198e-07 (rank : 7)
Query Neighborhood Hits	263	Target Neighborhood Hits	485	Shared Neighborhood Hits	62
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

EM55_MOUSE
NC score	0.178020 (rank : 115)	θ value	0.00134147 (rank : 41)
Query Neighborhood Hits	263	Target Neighborhood Hits	221	Shared Neighborhood Hits	78
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

DCC_HUMAN
NC score	0.176691 (rank : 116)	θ value	0.00509761 (rank : 61)
Query Neighborhood Hits	263	Target Neighborhood Hits	583	Shared Neighborhood Hits	63
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

PTPRD_MOUSE
NC score	0.175732 (rank : 117)	θ value	7.1131e-05 (rank : 19)
Query Neighborhood Hits	263	Target Neighborhood Hits	491	Shared Neighborhood Hits	63
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

ARHG9_MOUSE
NC score	0.173850 (rank : 118)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	263	Target Neighborhood Hits	234	Shared Neighborhood Hits	104
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG9_HUMAN
NC score	0.173440 (rank : 119)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	263	Target Neighborhood Hits	235	Shared Neighborhood Hits	104
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

PEX13_MOUSE
NC score	0.173358 (rank : 120)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	263	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_HUMAN
NC score	0.172245 (rank : 121)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	263	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PTPRF_HUMAN
NC score	0.171949 (rank : 122)	θ value	3.41135e-07 (rank : 9)
Query Neighborhood Hits	263	Target Neighborhood Hits	489	Shared Neighborhood Hits	60
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

DCC_MOUSE
NC score	0.171865 (rank : 123)	θ value	0.0563607 (rank : 89)
Query Neighborhood Hits	263	Target Neighborhood Hits	896	Shared Neighborhood Hits	76
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ARHG4_HUMAN
NC score	0.170951 (rank : 124)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	263	Target Neighborhood Hits	242	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

SHAN2_MOUSE
NC score	0.169007 (rank : 125)	θ value	0.0431538 (rank : 86)
Query Neighborhood Hits	263	Target Neighborhood Hits	446	Shared Neighborhood Hits	85
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

RHG26_HUMAN
NC score	0.168514 (rank : 126)	θ value	0.163984 (rank : 111)
Query Neighborhood Hits	263	Target Neighborhood Hits	281	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

PLCG1_MOUSE
NC score	0.168187 (rank : 127)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	263	Target Neighborhood Hits	314	Shared Neighborhood Hits	107
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

DSCL1_HUMAN
NC score	0.166391 (rank : 128)	θ value	0.00390308 (rank : 58)
Query Neighborhood Hits	263	Target Neighborhood Hits	589	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

COCA1_MOUSE
NC score	0.165834 (rank : 129)	θ value	0.163984 (rank : 106)
Query Neighborhood Hits	263	Target Neighborhood Hits	467	Shared Neighborhood Hits	66
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

PLCG2_HUMAN
NC score	0.165776 (rank : 130)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	263	Target Neighborhood Hits	280	Shared Neighborhood Hits	99
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PLCG1_HUMAN
NC score	0.162658 (rank : 131)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	263	Target Neighborhood Hits	293	Shared Neighborhood Hits	102
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

TENR_HUMAN
NC score	0.158286 (rank : 132)	θ value	0.000121331 (rank : 23)
Query Neighborhood Hits	263	Target Neighborhood Hits	526	Shared Neighborhood Hits	58
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

COCA1_HUMAN
NC score	0.157672 (rank : 133)	θ value	0.279714 (rank : 124)
Query Neighborhood Hits	263	Target Neighborhood Hits	458	Shared Neighborhood Hits	60
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

SHLB2_MOUSE
NC score	0.155204 (rank : 134)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	263	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_HUMAN
NC score	0.155202 (rank : 135)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	263	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

NEBU_HUMAN
NC score	0.154846 (rank : 136)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	263	Target Neighborhood Hits	420	Shared Neighborhood Hits	107
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

TENR_MOUSE
NC score	0.154693 (rank : 137)	θ value	9.29e-05 (rank : 22)
Query Neighborhood Hits	263	Target Neighborhood Hits	531	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

IASPP_HUMAN
NC score	0.150854 (rank : 138)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	263	Target Neighborhood Hits	688	Shared Neighborhood Hits	110
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NOXO1_MOUSE
NC score	0.150334 (rank : 139)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	263	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

MYO1F_HUMAN
NC score	0.149281 (rank : 140)	θ value	0.00298849 (rank : 53)
Query Neighborhood Hits	263	Target Neighborhood Hits	275	Shared Neighborhood Hits	120
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

ROBO1_HUMAN
NC score	0.149152 (rank : 141)	θ value	0.00509761 (rank : 62)
Query Neighborhood Hits	263	Target Neighborhood Hits	529	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

DDEF1_MOUSE
NC score	0.149066 (rank : 142)	θ value	0.365318 (rank : 132)
Query Neighborhood Hits	263	Target Neighborhood Hits	592	Shared Neighborhood Hits	105
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

MYOM1_HUMAN
NC score	0.148986 (rank : 143)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	263	Target Neighborhood Hits	405	Shared Neighborhood Hits	62
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

DDEF2_MOUSE
NC score	0.148051 (rank : 144)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	263	Target Neighborhood Hits	625	Shared Neighborhood Hits	103
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ROBO1_MOUSE
NC score	0.146797 (rank : 145)	θ value	0.125558 (rank : 103)
Query Neighborhood Hits	263	Target Neighborhood Hits	559	Shared Neighborhood Hits	61
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO3_MOUSE
NC score	0.146485 (rank : 146)	θ value	0.0563607 (rank : 90)
Query Neighborhood Hits	263	Target Neighborhood Hits	524	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

MYO1F_MOUSE
NC score	0.146413 (rank : 147)	θ value	0.00665767 (rank : 66)
Query Neighborhood Hits	263	Target Neighborhood Hits	262	Shared Neighborhood Hits	122
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NRCAM_HUMAN
NC score	0.146245 (rank : 148)	θ value	0.163984 (rank : 110)
Query Neighborhood Hits	263	Target Neighborhood Hits	439	Shared Neighborhood Hits	57
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

DSCAM_HUMAN
NC score	0.145732 (rank : 149)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	263	Target Neighborhood Hits	524	Shared Neighborhood Hits	61
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

ARHG4_MOUSE
NC score	0.144961 (rank : 150)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	263	Target Neighborhood Hits	185	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

DDEF2_HUMAN
NC score	0.143850 (rank : 151)	θ value	0.47712 (rank : 139)
Query Neighborhood Hits	263	Target Neighborhood Hits	599	Shared Neighborhood Hits	107
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CNTN3_HUMAN
NC score	0.143797 (rank : 152)	θ value	0.0736092 (rank : 92)
Query Neighborhood Hits	263	Target Neighborhood Hits	455	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

ROBO2_HUMAN
NC score	0.143597 (rank : 153)	θ value	0.125558 (rank : 104)
Query Neighborhood Hits	263	Target Neighborhood Hits	479	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

MPP6_HUMAN
NC score	0.143478 (rank : 154)	θ value	0.62314 (rank : 149)
Query Neighborhood Hits	263	Target Neighborhood Hits	180	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

ROBO2_MOUSE
NC score	0.143476 (rank : 155)	θ value	0.163984 (rank : 112)
Query Neighborhood Hits	263	Target Neighborhood Hits	504	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

RHG04_HUMAN
NC score	0.143046 (rank : 156)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	263	Target Neighborhood Hits	307	Shared Neighborhood Hits	111
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

IASPP_MOUSE
NC score	0.141510 (rank : 157)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	263	Target Neighborhood Hits	1024	Shared Neighborhood Hits	120
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MYOM1_MOUSE
NC score	0.140730 (rank : 158)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	263	Target Neighborhood Hits	415	Shared Neighborhood Hits	60
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

RUSC1_HUMAN
NC score	0.140335 (rank : 159)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	263	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

L1CAM_HUMAN
NC score	0.140310 (rank : 160)	θ value	1.38821 (rank : 173)
Query Neighborhood Hits	263	Target Neighborhood Hits	457	Shared Neighborhood Hits	62
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CNTN3_MOUSE
NC score	0.139880 (rank : 161)	θ value	1.06291 (rank : 160)
Query Neighborhood Hits	263	Target Neighborhood Hits	447	Shared Neighborhood Hits	61
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

MPP6_MOUSE
NC score	0.139392 (rank : 162)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	263	Target Neighborhood Hits	187	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MYOM2_HUMAN
NC score	0.139300 (rank : 163)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	263	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

CHL1_HUMAN
NC score	0.139013 (rank : 164)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	263	Target Neighborhood Hits	413	Shared Neighborhood Hits	57
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

TENN_MOUSE
NC score	0.138934 (rank : 165)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	263	Target Neighborhood Hits	484	Shared Neighborhood Hits	60
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MYPC3_MOUSE
NC score	0.138385 (rank : 166)	θ value	0.163984 (rank : 109)
Query Neighborhood Hits	263	Target Neighborhood Hits	310	Shared Neighborhood Hits	60
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MYPC3_HUMAN
NC score	0.137526 (rank : 167)	θ value	0.163984 (rank : 108)
Query Neighborhood Hits	263	Target Neighborhood Hits	318	Shared Neighborhood Hits	58
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MPP2_MOUSE
NC score	0.137193 (rank : 168)	θ value	0.0736092 (rank : 93)
Query Neighborhood Hits	263	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

NRCAM_MOUSE
NC score	0.136379 (rank : 169)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	263	Target Neighborhood Hits	432	Shared Neighborhood Hits	55
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

L1CAM_MOUSE
NC score	0.136183 (rank : 170)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	263	Target Neighborhood Hits	457	Shared Neighborhood Hits	61
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

COEA1_MOUSE
NC score	0.135746 (rank : 171)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	263	Target Neighborhood Hits	402	Shared Neighborhood Hits	64
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CNTN4_MOUSE
NC score	0.135449 (rank : 172)	θ value	0.21417 (rank : 118)
Query Neighborhood Hits	263	Target Neighborhood Hits	445	Shared Neighborhood Hits	59
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

ROBO3_HUMAN
NC score	0.134689 (rank : 173)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	263	Target Neighborhood Hits	570	Shared Neighborhood Hits	61
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

CNTN6_MOUSE
NC score	0.133975 (rank : 174)	θ value	1.38821 (rank : 170)
Query Neighborhood Hits	263	Target Neighborhood Hits	429	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

PUNC_MOUSE
NC score	0.133525 (rank : 175)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	263	Target Neighborhood Hits	501	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

CNTN4_HUMAN
NC score	0.133456 (rank : 176)	θ value	0.21417 (rank : 117)
Query Neighborhood Hits	263	Target Neighborhood Hits	449	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

ROBO4_HUMAN
NC score	0.133083 (rank : 177)	θ value	0.365318 (rank : 134)
Query Neighborhood Hits	263	Target Neighborhood Hits	364	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

NFASC_HUMAN
NC score	0.133028 (rank : 178)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	263	Target Neighborhood Hits	497	Shared Neighborhood Hits	59
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

MYPC2_MOUSE
NC score	0.133004 (rank : 179)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	263	Target Neighborhood Hits	297	Shared Neighborhood Hits	58
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

PUNC_HUMAN
NC score	0.132770 (rank : 180)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	263	Target Neighborhood Hits	449	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

MPP2_HUMAN
NC score	0.131825 (rank : 181)	θ value	0.21417 (rank : 119)
Query Neighborhood Hits	263	Target Neighborhood Hits	173	Shared Neighborhood Hits	58
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

ASPP1_MOUSE
NC score	0.131791 (rank : 182)	θ value	0.62314 (rank : 144)
Query Neighborhood Hits	263	Target Neighborhood Hits	1244	Shared Neighborhood Hits	131
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MYPC2_HUMAN
NC score	0.130680 (rank : 183)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	263	Target Neighborhood Hits	316	Shared Neighborhood Hits	57
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

CNTN6_HUMAN
NC score	0.130424 (rank : 184)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	263	Target Neighborhood Hits	422	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

ES8L3_MOUSE
NC score	0.130283 (rank : 185)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	263	Target Neighborhood Hits	168	Shared Neighborhood Hits	92
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

COEA1_HUMAN
NC score	0.129856 (rank : 186)	θ value	0.365318 (rank : 131)
Query Neighborhood Hits	263	Target Neighborhood Hits	427	Shared Neighborhood Hits	66
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

ASPP2_HUMAN
NC score	0.129214 (rank : 187)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	263	Target Neighborhood Hits	1156	Shared Neighborhood Hits	129
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CNTN1_HUMAN
NC score	0.129176 (rank : 188)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	263	Target Neighborhood Hits	431	Shared Neighborhood Hits	55
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

RUSC1_MOUSE
NC score	0.128900 (rank : 189)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	263	Target Neighborhood Hits	206	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

NFASC_MOUSE
NC score	0.128595 (rank : 190)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	263	Target Neighborhood Hits	475	Shared Neighborhood Hits	61
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

CHL1_MOUSE
NC score	0.128490 (rank : 191)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	263	Target Neighborhood Hits	402	Shared Neighborhood Hits	56
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CNTN1_MOUSE
NC score	0.127499 (rank : 192)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	263	Target Neighborhood Hits	422	Shared Neighborhood Hits	55
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_HUMAN
NC score	0.127258 (rank : 193)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	263	Target Neighborhood Hits	440	Shared Neighborhood Hits	58
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
NC score	0.126230 (rank : 194)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	263	Target Neighborhood Hits	450	Shared Neighborhood Hits	57
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN5_MOUSE
NC score	0.125550 (rank : 195)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	263	Target Neighborhood Hits	434	Shared Neighborhood Hits	56
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

ASPP1_HUMAN
NC score	0.125355 (rank : 196)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	263	Target Neighborhood Hits	956	Shared Neighborhood Hits	127
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TENN_HUMAN
NC score	0.125086 (rank : 197)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	263	Target Neighborhood Hits	453	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

USH2A_HUMAN
NC score	0.124962 (rank : 198)	θ value	0.0563607 (rank : 91)
Query Neighborhood Hits	263	Target Neighborhood Hits	600	Shared Neighborhood Hits	62
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

SRGP2_MOUSE
NC score	0.124588 (rank : 199)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	263	Target Neighborhood Hits	324	Shared Neighborhood Hits	101
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CNTN5_HUMAN
NC score	0.124555 (rank : 200)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	263	Target Neighborhood Hits	446	Shared Neighborhood Hits	57
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

SRGP2_HUMAN
NC score	0.124252 (rank : 201)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	263	Target Neighborhood Hits	331	Shared Neighborhood Hits	99
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

COKA1_HUMAN
NC score	0.123882 (rank : 202)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	263	Target Neighborhood Hits	403	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

SHAN1_HUMAN
NC score	0.123554 (rank : 203)	θ value	0.47712 (rank : 142)
Query Neighborhood Hits	263	Target Neighborhood Hits	1041	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

MYPC1_HUMAN
NC score	0.122620 (rank : 204)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	263	Target Neighborhood Hits	303	Shared Neighborhood Hits	57
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

MYO1E_HUMAN
NC score	0.121637 (rank : 205)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	263	Target Neighborhood Hits	293	Shared Neighborhood Hits	119
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

ANM2_HUMAN
NC score	0.121409 (rank : 206)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	263	Target Neighborhood Hits	175	Shared Neighborhood Hits	90
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ROBO4_MOUSE
NC score	0.117694 (rank : 207)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	263	Target Neighborhood Hits	358	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

USH2A_MOUSE
NC score	0.117011 (rank : 208)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	263	Target Neighborhood Hits	626	Shared Neighborhood Hits	64
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

TENA_MOUSE
NC score	0.116122 (rank : 209)	θ value	0.000461057 (rank : 35)
Query Neighborhood Hits	263	Target Neighborhood Hits	596	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

PTPRB_HUMAN
NC score	0.115782 (rank : 210)	θ value	0.365318 (rank : 133)
Query Neighborhood Hits	263	Target Neighborhood Hits	242	Shared Neighborhood Hits	49
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

CDON_MOUSE
NC score	0.114360 (rank : 211)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	263	Target Neighborhood Hits	410	Shared Neighborhood Hits	53
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

BOC_HUMAN
NC score	0.114101 (rank : 212)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	263	Target Neighborhood Hits	543	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

MPP3_MOUSE
NC score	0.113935 (rank : 213)	θ value	0.0431538 (rank : 85)
Query Neighborhood Hits	263	Target Neighborhood Hits	165	Shared Neighborhood Hits	33
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

CDON_HUMAN
NC score	0.113343 (rank : 214)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	263	Target Neighborhood Hits	412	Shared Neighborhood Hits	53
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

MPP3_HUMAN
NC score	0.112968 (rank : 215)	θ value	0.21417 (rank : 120)
Query Neighborhood Hits	263	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

BOC_MOUSE
NC score	0.112129 (rank : 216)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	263	Target Neighborhood Hits	433	Shared Neighborhood Hits	57
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

ANM2_MOUSE
NC score	0.111639 (rank : 217)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	263	Target Neighborhood Hits	175	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ES8L3_HUMAN
NC score	0.108541 (rank : 218)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	263	Target Neighborhood Hits	206	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

MPP4_MOUSE
NC score	0.108281 (rank : 219)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	263	Target Neighborhood Hits	188	Shared Neighborhood Hits	49
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

NCAM2_MOUSE
NC score	0.108159 (rank : 220)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	263	Target Neighborhood Hits	472	Shared Neighborhood Hits	55
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

TENA_HUMAN
NC score	0.107080 (rank : 221)	θ value	0.163984 (rank : 114)
Query Neighborhood Hits	263	Target Neighborhood Hits	631	Shared Neighborhood Hits	59
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

NPHN_HUMAN
NC score	0.106539 (rank : 222)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	263	Target Neighborhood Hits	362	Shared Neighborhood Hits	56
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

ES8L2_MOUSE
NC score	0.105722 (rank : 223)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	263	Target Neighborhood Hits	169	Shared Neighborhood Hits	81
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

NCAM2_HUMAN
NC score	0.105191 (rank : 224)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	263	Target Neighborhood Hits	441	Shared Neighborhood Hits	55
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

SPTA2_HUMAN
NC score	0.105117 (rank : 225)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	263	Target Neighborhood Hits	888	Shared Neighborhood Hits	130
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRGP1_HUMAN
NC score	0.105077 (rank : 226)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	263	Target Neighborhood Hits	390	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

CO7A1_HUMAN
NC score	0.104095 (rank : 227)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	263	Target Neighborhood Hits	807	Shared Neighborhood Hits	61
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

ES8L2_HUMAN
NC score	0.103461 (rank : 228)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	263	Target Neighborhood Hits	193	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ARHG5_HUMAN
NC score	0.102970 (rank : 229)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	263	Target Neighborhood Hits	172	Shared Neighborhood Hits	68
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

OBSL1_HUMAN
NC score	0.102786 (rank : 230)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	263	Target Neighborhood Hits	354	Shared Neighborhood Hits	38
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

ITB4_HUMAN
NC score	0.100519 (rank : 231)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	263	Target Neighborhood Hits	458	Shared Neighborhood Hits	56
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

NPHN_MOUSE
NC score	0.100281 (rank : 232)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	263	Target Neighborhood Hits	370	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

TENX_HUMAN
NC score	0.099976 (rank : 233)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	263	Target Neighborhood Hits	789	Shared Neighborhood Hits	64
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NCA11_MOUSE
NC score	0.099665 (rank : 234)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	263	Target Neighborhood Hits	661	Shared Neighborhood Hits	62
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

FNBP2_HUMAN
NC score	0.099560 (rank : 235)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	263	Target Neighborhood Hits	432	Shared Neighborhood Hits	101
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

SPTA1_HUMAN
NC score	0.099499 (rank : 236)	θ value	0.813845 (rank : 157)
Query Neighborhood Hits	263	Target Neighborhood Hits	748	Shared Neighborhood Hits	117
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

STS2_HUMAN
NC score	0.099230 (rank : 237)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	263	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

MPP5_HUMAN
NC score	0.099157 (rank : 238)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	263	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

NOXO1_HUMAN
NC score	0.099108 (rank : 239)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	263	Target Neighborhood Hits	100	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

MPP5_MOUSE
NC score	0.098656 (rank : 240)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	263	Target Neighborhood Hits	226	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

TITIN_HUMAN
NC score	0.098319 (rank : 241)	θ value	0.0736092 (rank : 96)
Query Neighborhood Hits	263	Target Neighborhood Hits	2923	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

NCA11_HUMAN
NC score	0.097918 (rank : 242)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	263	Target Neighborhood Hits	443	Shared Neighborhood Hits	51
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

MYBPH_MOUSE
NC score	0.097588 (rank : 243)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	263	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NGEF_MOUSE
NC score	0.097087 (rank : 244)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	263	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

MYBPH_HUMAN
NC score	0.096488 (rank : 245)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	263	Target Neighborhood Hits	256	Shared Neighborhood Hits	51
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NCA12_MOUSE
NC score	0.096033 (rank : 246)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	263	Target Neighborhood Hits	399	Shared Neighborhood Hits	49
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

BI2L1_HUMAN
NC score	0.095666 (rank : 247)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	263	Target Neighborhood Hits	156	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

SPN90_HUMAN
NC score	0.095418 (rank : 248)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	263	Target Neighborhood Hits	157	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

FGR_HUMAN
NC score	0.094642 (rank : 249)	θ value	7.1131e-05 (rank : 17)
Query Neighborhood Hits	263	Target Neighborhood Hits	1067	Shared Neighborhood Hits	125
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

NGEF_HUMAN
NC score	0.094475 (rank : 250)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	263	Target Neighborhood Hits	166	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NCA12_HUMAN
NC score	0.094422 (rank : 251)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	263	Target Neighborhood Hits	437	Shared Neighborhood Hits	49
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

M3KL4_HUMAN
NC score	0.094183 (rank : 252)	θ value	0.0330416 (rank : 82)
Query Neighborhood Hits	263	Target Neighborhood Hits	1087	Shared Neighborhood Hits	124
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

SPTA1_MOUSE
NC score	0.093499 (rank : 253)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	263	Target Neighborhood Hits	675	Shared Neighborhood Hits	114
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

IL6RB_MOUSE
NC score	0.092139 (rank : 254)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	263	Target Neighborhood Hits	168	Shared Neighborhood Hits	49
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

MYPN_HUMAN
NC score	0.092034 (rank : 255)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	263	Target Neighborhood Hits	418	Shared Neighborhood Hits	43
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

IL6RB_HUMAN
NC score	0.091807 (rank : 256)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	263	Target Neighborhood Hits	181	Shared Neighborhood Hits	46
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

TCGAP_MOUSE
NC score	0.091769 (rank : 257)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	263	Target Neighborhood Hits	409	Shared Neighborhood Hits	93
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PTPRM_MOUSE
NC score	0.091541 (rank : 258)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	263	Target Neighborhood Hits	238	Shared Neighborhood Hits	53
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.091540 (rank : 259)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	263	Target Neighborhood Hits	244	Shared Neighborhood Hits	53
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

FGRL1_HUMAN
NC score	0.091354 (rank : 260)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	263	Target Neighborhood Hits	335	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

MYPN_MOUSE
NC score	0.091014 (rank : 261)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	263	Target Neighborhood Hits	421	Shared Neighborhood Hits	44
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

LIFR_MOUSE
NC score	0.090866 (rank : 262)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	263	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

LIFR_HUMAN
NC score	0.090295 (rank : 263)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	263	Target Neighborhood Hits	130	Shared Neighborhood Hits	41
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

MYOTI_MOUSE
NC score	0.090122 (rank : 264)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	263	Target Neighborhood Hits	297	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

FGRL1_MOUSE
NC score	0.089683 (rank : 265)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	263	Target Neighborhood Hits	325	Shared Neighborhood Hits	38
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

M3K11_HUMAN
NC score	0.089512 (rank : 266)	θ value	0.279714 (rank : 128)
Query Neighborhood Hits	263	Target Neighborhood Hits	1136	Shared Neighborhood Hits	129
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

AMPH_HUMAN
NC score	0.089498 (rank : 267)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	263	Target Neighborhood Hits	455	Shared Neighborhood Hits	68
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

MYOTI_HUMAN
NC score	0.089341 (rank : 268)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

CIP4_HUMAN
NC score	0.087946 (rank : 269)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	263	Target Neighborhood Hits	374	Shared Neighborhood Hits	58
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

PTPRT_MOUSE
NC score	0.087866 (rank : 270)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	263	Target Neighborhood Hits	219	Shared Neighborhood Hits	49
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.087512 (rank : 271)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	263	Target Neighborhood Hits	217	Shared Neighborhood Hits	48
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

I12R2_HUMAN
NC score	0.086944 (rank : 272)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	263	Target Neighborhood Hits	163	Shared Neighborhood Hits	46
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

EPS8_HUMAN
NC score	0.086489 (rank : 273)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	263	Target Neighborhood Hits	151	Shared Neighborhood Hits	75
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

TCGAP_HUMAN
NC score	0.086115 (rank : 274)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	263	Target Neighborhood Hits	872	Shared Neighborhood Hits	107
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

EPS8_MOUSE
NC score	0.086066 (rank : 275)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	263	Target Neighborhood Hits	157	Shared Neighborhood Hits	79
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

SRC_HUMAN
NC score	0.085453 (rank : 276)	θ value	0.163984 (rank : 113)
Query Neighborhood Hits	263	Target Neighborhood Hits	1058	Shared Neighborhood Hits	125
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

FGR_MOUSE
NC score	0.085423 (rank : 277)	θ value	1.38821 (rank : 172)
Query Neighborhood Hits	263	Target Neighborhood Hits	1069	Shared Neighborhood Hits	124
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

PKHG1_HUMAN
NC score	0.084991 (rank : 278)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	263	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

BTK_HUMAN
NC score	0.084219 (rank : 279)	θ value	0.00175202 (rank : 50)
Query Neighborhood Hits	263	Target Neighborhood Hits	1026	Shared Neighborhood Hits	118
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

MALT1_HUMAN
NC score	0.084129 (rank : 280)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	263	Target Neighborhood Hits	236	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

PTPRV_MOUSE
NC score	0.084117 (rank : 281)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	263	Target Neighborhood Hits	179	Shared Neighborhood Hits	39
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

KALM_HUMAN
NC score	0.083689 (rank : 282)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	263	Target Neighborhood Hits	114	Shared Neighborhood Hits	34
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

I12R2_MOUSE
NC score	0.083640 (rank : 283)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	263	Target Neighborhood Hits	143	Shared Neighborhood Hits	44
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

YES_MOUSE
NC score	0.083453 (rank : 284)	θ value	1.06291 (rank : 168)
Query Neighborhood Hits	263	Target Neighborhood Hits	1052	Shared Neighborhood Hits	122
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_HUMAN
NC score	0.083044 (rank : 285)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	263	Target Neighborhood Hits	1059	Shared Neighborhood Hits	123
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

FYN_MOUSE
NC score	0.082961 (rank : 286)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	263	Target Neighborhood Hits	1073	Shared Neighborhood Hits	123
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

SPN90_MOUSE
NC score	0.082344 (rank : 287)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	263	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

MPP4_HUMAN
NC score	0.082097 (rank : 288)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	263	Target Neighborhood Hits	205	Shared Neighborhood Hits	45
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

KAZD1_MOUSE
NC score	0.082073 (rank : 289)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	263	Target Neighborhood Hits	281	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

TARSH_HUMAN
NC score	0.081807 (rank : 290)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	263	Target Neighborhood Hits	768	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

ARHG3_HUMAN
NC score	0.081721 (rank : 291)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	263	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
NC score	0.081641 (rank : 292)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	263	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

FYN_HUMAN
NC score	0.081580 (rank : 293)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	263	Target Neighborhood Hits	1078	Shared Neighborhood Hits	123
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

ES8L1_MOUSE
NC score	0.081448 (rank : 294)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	263	Target Neighborhood Hits	143	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

PTPRJ_MOUSE
NC score	0.081133 (rank : 295)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	263	Target Neighborhood Hits	188	Shared Neighborhood Hits	39
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

BTK_MOUSE
NC score	0.081021 (rank : 296)	θ value	0.00390308 (rank : 57)
Query Neighborhood Hits	263	Target Neighborhood Hits	1017	Shared Neighborhood Hits	115
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

MAMC1_MOUSE
NC score	0.080534 (rank : 297)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	263	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

ARHGG_MOUSE
NC score	0.080251 (rank : 298)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	263	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

MAMC1_HUMAN
NC score	0.080200 (rank : 299)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	263	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

KAZD1_HUMAN
NC score	0.079864 (rank : 300)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	263	Target Neighborhood Hits	248	Shared Neighborhood Hits	37
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

PTPRU_HUMAN
NC score	0.079708 (rank : 301)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	263	Target Neighborhood Hits	237	Shared Neighborhood Hits	50
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PPIP2_HUMAN
NC score	0.079682 (rank : 302)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	263	Target Neighborhood Hits	254	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

PTPRJ_HUMAN
NC score	0.079495 (rank : 303)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	263	Target Neighborhood Hits	207	Shared Neighborhood Hits	36
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

TIAM1_MOUSE
NC score	0.079326 (rank : 304)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	263	Target Neighborhood Hits	205	Shared Neighborhood Hits	23
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ES8L1_HUMAN
NC score	0.079268 (rank : 305)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	263	Target Neighborhood Hits	162	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

MDGA1_HUMAN
NC score	0.078744 (rank : 306)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	263	Target Neighborhood Hits	358	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

SLY_MOUSE
NC score	0.078348 (rank : 307)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	263	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

M3K9_HUMAN
NC score	0.078098 (rank : 308)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	263	Target Neighborhood Hits	1123	Shared Neighborhood Hits	119
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

PREX1_HUMAN
NC score	0.078091 (rank : 309)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	263	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

P85A_MOUSE
NC score	0.078059 (rank : 310)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	263	Target Neighborhood Hits	435	Shared Neighborhood Hits	72
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

AMPH_MOUSE
NC score	0.078035 (rank : 311)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	263	Target Neighborhood Hits	291	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ARHG8_MOUSE
NC score	0.077763 (rank : 312)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	263	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

TIAM1_HUMAN
NC score	0.077633 (rank : 313)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	263	Target Neighborhood Hits	225	Shared Neighborhood Hits	21
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PTPRK_MOUSE
NC score	0.075832 (rank : 314)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	263	Target Neighborhood Hits	223	Shared Neighborhood Hits	48
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

P85A_HUMAN
NC score	0.075010 (rank : 315)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	263	Target Neighborhood Hits	479	Shared Neighborhood Hits	69
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PTPRK_HUMAN
NC score	0.074992 (rank : 316)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	263	Target Neighborhood Hits	228	Shared Neighborhood Hits	48
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

TMIGD_HUMAN
NC score	0.074784 (rank : 317)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	263	Target Neighborhood Hits	240	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

JAM3_HUMAN
NC score	0.074615 (rank : 318)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

TMIGD_MOUSE
NC score	0.074227 (rank : 319)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	263	Target Neighborhood Hits	234	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

IBP7_MOUSE
NC score	0.074091 (rank : 320)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	263	Target Neighborhood Hits	230	Shared Neighborhood Hits	37
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

CSF3R_HUMAN
NC score	0.074068 (rank : 321)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	263	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

KIRR2_HUMAN
NC score	0.073861 (rank : 322)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	263	Target Neighborhood Hits	321	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

PPIP2_MOUSE
NC score	0.073708 (rank : 323)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	263	Target Neighborhood Hits	308	Shared Neighborhood Hits	25
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

BI2L1_MOUSE
NC score	0.073055 (rank : 324)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	263	Target Neighborhood Hits	197	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

STS1_HUMAN
NC score	0.072817 (rank : 325)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	263	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

NEGR1_HUMAN
NC score	0.072767 (rank : 326)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	263	Target Neighborhood Hits	346	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

MCF2L_MOUSE
NC score	0.072622 (rank : 327)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	263	Target Neighborhood Hits	255	Shared Neighborhood Hits	37
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

KIRR2_MOUSE
NC score	0.072390 (rank : 328)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	263	Target Neighborhood Hits	326	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

BIN1_MOUSE
NC score	0.072334 (rank : 329)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	263	Target Neighborhood Hits	283	Shared Neighborhood Hits	62
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

MAG_MOUSE
NC score	0.072265 (rank : 330)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	37
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

STS1_MOUSE
NC score	0.072218 (rank : 331)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	263	Target Neighborhood Hits	104	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

M3K10_HUMAN
NC score	0.072210 (rank : 332)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	263	Target Neighborhood Hits	1071	Shared Neighborhood Hits	118
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MAG_HUMAN
NC score	0.072173 (rank : 333)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	263	Target Neighborhood Hits	278	Shared Neighborhood Hits	37
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

DOCK1_HUMAN
NC score	0.072146 (rank : 334)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	263	Target Neighborhood Hits	191	Shared Neighborhood Hits	83
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

LSAMP_MOUSE
NC score	0.071878 (rank : 335)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	263	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

RAGE_HUMAN
NC score	0.071597 (rank : 336)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	263	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

FSTL5_MOUSE
NC score	0.071471 (rank : 337)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	263	Target Neighborhood Hits	355	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FSTL5_HUMAN
NC score	0.071414 (rank : 338)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	263	Target Neighborhood Hits	347	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

LSAMP_HUMAN
NC score	0.071308 (rank : 339)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	263	Target Neighborhood Hits	347	Shared Neighborhood Hits	37
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

NEGR1_MOUSE
NC score	0.071268 (rank : 340)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	263	Target Neighborhood Hits	349	Shared Neighborhood Hits	37
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

FSTL4_MOUSE
NC score	0.071202 (rank : 341)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	263	Target Neighborhood Hits	333	Shared Neighborhood Hits	37
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

BIN1_HUMAN
NC score	0.071161 (rank : 342)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	263	Target Neighborhood Hits	335	Shared Neighborhood Hits	58
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

ARHG8_HUMAN
NC score	0.070908 (rank : 343)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	263	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

SLAP2_MOUSE
NC score	0.070804 (rank : 344)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	263	Target Neighborhood Hits	136	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SLAP2_HUMAN
NC score	0.070621 (rank : 345)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	263	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

OPCM_HUMAN
NC score	0.070509 (rank : 346)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	263	Target Neighborhood Hits	332	Shared Neighborhood Hits	37
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

NPTN_HUMAN
NC score	0.070457 (rank : 347)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	263	Target Neighborhood Hits	212	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

MUC18_HUMAN
NC score	0.070351 (rank : 348)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	263	Target Neighborhood Hits	275	Shared Neighborhood Hits	36
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

CT075_HUMAN
NC score	0.070076 (rank : 349)	θ value	1.06291 (rank : 161)
Query Neighborhood Hits	263	Target Neighborhood Hits	387	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

NPTN_MOUSE
NC score	0.069988 (rank : 350)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	263	Target Neighborhood Hits	216	Shared Neighborhood Hits	36
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

SORL_HUMAN
NC score	0.069837 (rank : 351)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	263	Target Neighborhood Hits	440	Shared Neighborhood Hits	55
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

NRG2_HUMAN
NC score	0.069820 (rank : 352)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	263	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

SLY_HUMAN
NC score	0.069487 (rank : 353)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	263	Target Neighborhood Hits	81	Shared Neighborhood Hits	46
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

JAM3_MOUSE
NC score	0.069414 (rank : 354)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	263	Target Neighborhood Hits	286	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

RAGE_MOUSE
NC score	0.069289 (rank : 355)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	263	Target Neighborhood Hits	295	Shared Neighborhood Hits	37
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

GLE1_HUMAN
NC score	0.069250 (rank : 356)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	263	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

FSTL4_HUMAN
NC score	0.069199 (rank : 357)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	263	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

VCAM1_MOUSE
NC score	0.068714 (rank : 358)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	263	Target Neighborhood Hits	320	Shared Neighborhood Hits	37
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

CI094_HUMAN
NC score	0.068370 (rank : 359)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	263	Target Neighborhood Hits	310	Shared Neighborhood Hits	37
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ICAM5_MOUSE
NC score	0.068258 (rank : 360)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	263	Target Neighborhood Hits	308	Shared Neighborhood Hits	36
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

PTN11_HUMAN
NC score	0.068177 (rank : 361)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.068176 (rank : 362)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

ARHGG_HUMAN
NC score	0.067843 (rank : 363)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	263	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

PTPRO_HUMAN
NC score	0.067768 (rank : 364)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	263	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

VCAM1_HUMAN
NC score	0.067731 (rank : 365)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	263	Target Neighborhood Hits	352	Shared Neighborhood Hits	38
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

SRC_MOUSE
NC score	0.067595 (rank : 366)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	263	Target Neighborhood Hits	1033	Shared Neighborhood Hits	107
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

DUET_HUMAN
NC score	0.067521 (rank : 367)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	263	Target Neighborhood Hits	1220	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ARHGA_MOUSE
NC score	0.067031 (rank : 368)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	263	Target Neighborhood Hits	125	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

GLE1_MOUSE
NC score	0.066986 (rank : 369)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	263	Target Neighborhood Hits	504	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

IBP7_HUMAN
NC score	0.066932 (rank : 370)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	263	Target Neighborhood Hits	220	Shared Neighborhood Hits	34
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

NTRI_MOUSE
NC score	0.066600 (rank : 371)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	263	Target Neighborhood Hits	342	Shared Neighborhood Hits	37
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

CSK_MOUSE
NC score	0.065937 (rank : 372)	θ value	0.47712 (rank : 137)
Query Neighborhood Hits	263	Target Neighborhood Hits	1009	Shared Neighborhood Hits	97
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CSK_HUMAN
NC score	0.065854 (rank : 373)	θ value	0.47712 (rank : 136)
Query Neighborhood Hits	263	Target Neighborhood Hits	1009	Shared Neighborhood Hits	97
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

JAM1_HUMAN
NC score	0.065791 (rank : 374)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	263	Target Neighborhood Hits	294	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

ICAM5_HUMAN
NC score	0.065779 (rank : 375)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	263	Target Neighborhood Hits	276	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

PTN6_MOUSE
NC score	0.065668 (rank : 376)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	263	Target Neighborhood Hits	225	Shared Neighborhood Hits	33
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

NTRI_HUMAN
NC score	0.065665 (rank : 377)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	263	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

PTN6_HUMAN
NC score	0.065474 (rank : 378)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	263	Target Neighborhood Hits	234	Shared Neighborhood Hits	32
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

ECT2_MOUSE
NC score	0.065394 (rank : 379)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	263	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

MUC18_MOUSE
NC score	0.065295 (rank : 380)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

LU_HUMAN
NC score	0.065184 (rank : 381)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	263	Target Neighborhood Hits	283	Shared Neighborhood Hits	37
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

JAM1_MOUSE
NC score	0.065052 (rank : 382)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	263	Target Neighborhood Hits	287	Shared Neighborhood Hits	36
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

PTK7_HUMAN
NC score	0.064997 (rank : 383)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	263	Target Neighborhood Hits	1103	Shared Neighborhood Hits	58
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

HCK_MOUSE
NC score	0.064493 (rank : 384)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	263	Target Neighborhood Hits	1029	Shared Neighborhood Hits	108
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

PGBM_HUMAN
NC score	0.064393 (rank : 385)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	263	Target Neighborhood Hits	1113	Shared Neighborhood Hits	49
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

BAIP2_MOUSE
NC score	0.064362 (rank : 386)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	263	Target Neighborhood Hits	185	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

ARHGA_HUMAN
NC score	0.064163 (rank : 387)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	263	Target Neighborhood Hits	187	Shared Neighborhood Hits	17
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

KIRR3_HUMAN
NC score	0.063978 (rank : 388)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	263	Target Neighborhood Hits	302	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

HCK_HUMAN
NC score	0.063831 (rank : 389)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	263	Target Neighborhood Hits	1035	Shared Neighborhood Hits	109
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

PGBM_MOUSE
NC score	0.063709 (rank : 390)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	263	Target Neighborhood Hits	1073	Shared Neighborhood Hits	50
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SORL_MOUSE
NC score	0.063698 (rank : 391)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	263	Target Neighborhood Hits	439	Shared Neighborhood Hits	52
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

KIRR1_HUMAN
NC score	0.063483 (rank : 392)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	263	Target Neighborhood Hits	401	Shared Neighborhood Hits	36
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

SLAP1_HUMAN
NC score	0.063417 (rank : 393)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	263	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

OBSCN_HUMAN
NC score	0.063275 (rank : 394)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	263	Target Neighborhood Hits	1931	Shared Neighborhood Hits	98
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

P85B_HUMAN
NC score	0.062939 (rank : 395)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	263	Target Neighborhood Hits	543	Shared Neighborhood Hits	61
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

HCFC2_MOUSE
NC score	0.062937 (rank : 396)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	263	Target Neighborhood Hits	97	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

KIRR3_MOUSE
NC score	0.062749 (rank : 397)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

CSKP_HUMAN
NC score	0.062611 (rank : 398)	θ value	0.125558 (rank : 99)
Query Neighborhood Hits	263	Target Neighborhood Hits	1022	Shared Neighborhood Hits	91
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

ECT2_HUMAN
NC score	0.062605 (rank : 399)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	263	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

BAIP2_HUMAN
NC score	0.062534 (rank : 400)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	263	Target Neighborhood Hits	192	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

CS029_HUMAN
NC score	0.062425 (rank : 401)	θ value	1.38821 (rank : 171)
Query Neighborhood Hits	263	Target Neighborhood Hits	329	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

SN_MOUSE
NC score	0.062367 (rank : 402)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	263	Target Neighborhood Hits	416	Shared Neighborhood Hits	38
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

HMCN1_HUMAN
NC score	0.062324 (rank : 403)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	263	Target Neighborhood Hits	983	Shared Neighborhood Hits	42
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

JAM2_HUMAN
NC score	0.062124 (rank : 404)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	263	Target Neighborhood Hits	304	Shared Neighborhood Hits	37
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

LYN_MOUSE
NC score	0.061915 (rank : 405)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	263	Target Neighborhood Hits	1023	Shared Neighborhood Hits	101
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

CS029_MOUSE
NC score	0.061857 (rank : 406)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	263	Target Neighborhood Hits	201	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

KIRR1_MOUSE
NC score	0.061735 (rank : 407)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	263	Target Neighborhood Hits	403	Shared Neighborhood Hits	36
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

CD22_MOUSE
NC score	0.061698 (rank : 408)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	263	Target Neighborhood Hits	331	Shared Neighborhood Hits	35
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

MUSK_MOUSE
NC score	0.061269 (rank : 409)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	263	Target Neighborhood Hits	1057	Shared Neighborhood Hits	57
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

BASI_HUMAN
NC score	0.061212 (rank : 410)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	263	Target Neighborhood Hits	211	Shared Neighborhood Hits	33
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

MCF2_HUMAN
NC score	0.061165 (rank : 411)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	263	Target Neighborhood Hits	166	Shared Neighborhood Hits	22
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

DLG2_HUMAN
NC score	0.061107 (rank : 412)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	263	Target Neighborhood Hits	279	Shared Neighborhood Hits	60
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

CD45_HUMAN
NC score	0.061074 (rank : 413)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	263	Target Neighborhood Hits	243	Shared Neighborhood Hits	39
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

MUSK_HUMAN
NC score	0.061000 (rank : 414)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	263	Target Neighborhood Hits	1074	Shared Neighborhood Hits	57
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

SLAP1_MOUSE
NC score	0.060997 (rank : 415)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	263	Target Neighborhood Hits	117	Shared Neighborhood Hits	22
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

BASI_MOUSE
NC score	0.060737 (rank : 416)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	263	Target Neighborhood Hits	238	Shared Neighborhood Hits	31
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

VSIG2_HUMAN
NC score	0.060693 (rank : 417)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	263	Target Neighborhood Hits	321	Shared Neighborhood Hits	36
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

MARCS_MOUSE
NC score	0.060583 (rank : 418)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

P85B_MOUSE
NC score	0.060538 (rank : 419)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	263	Target Neighborhood Hits	519	Shared Neighborhood Hits	60
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

LYN_HUMAN
NC score	0.060195 (rank : 420)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	263	Target Neighborhood Hits	1022	Shared Neighborhood Hits	101
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

KGUA_MOUSE
NC score	0.059621 (rank : 421)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	263	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

SN_HUMAN
NC score	0.059471 (rank : 422)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	263	Target Neighborhood Hits	434	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

LRIG2_HUMAN
NC score	0.059371 (rank : 423)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	263	Target Neighborhood Hits	595	Shared Neighborhood Hits	40
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

FRK_HUMAN
NC score	0.059361 (rank : 424)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	263	Target Neighborhood Hits	1058	Shared Neighborhood Hits	115
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

LRIG2_MOUSE
NC score	0.059137 (rank : 425)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	263	Target Neighborhood Hits	586	Shared Neighborhood Hits	40
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG1_HUMAN
NC score	0.058990 (rank : 426)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	263	Target Neighborhood Hits	654	Shared Neighborhood Hits	40
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

KGUA_HUMAN
NC score	0.058973 (rank : 427)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	263	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LRIG1_MOUSE
NC score	0.058792 (rank : 428)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	263	Target Neighborhood Hits	627	Shared Neighborhood Hits	39
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

DLG2_MOUSE
NC score	0.058493 (rank : 429)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	58
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

CSF3R_MOUSE
NC score	0.058286 (rank : 430)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	263	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

LRIG3_MOUSE
NC score	0.058284 (rank : 431)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	263	Target Neighborhood Hits	611	Shared Neighborhood Hits	40
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

TIE2_HUMAN
NC score	0.058278 (rank : 432)	θ value	0.279714 (rank : 129)
Query Neighborhood Hits	263	Target Neighborhood Hits	1192	Shared Neighborhood Hits	74
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

RASA1_HUMAN
NC score	0.058136 (rank : 433)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	263	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RGNEF_MOUSE
NC score	0.058042 (rank : 434)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	263	Target Neighborhood Hits	641	Shared Neighborhood Hits	43
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ARHG1_HUMAN
NC score	0.058041 (rank : 435)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	263	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

TYRO3_HUMAN
NC score	0.057952 (rank : 436)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	263	Target Neighborhood Hits	995	Shared Neighborhood Hits	66
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

CSKP_MOUSE
NC score	0.057924 (rank : 437)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	263	Target Neighborhood Hits	1027	Shared Neighborhood Hits	97
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

LRIG3_HUMAN
NC score	0.057905 (rank : 438)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	263	Target Neighborhood Hits	601	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

ARHGC_MOUSE
NC score	0.057886 (rank : 439)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	263	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

MFA3L_HUMAN
NC score	0.057882 (rank : 440)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	263	Target Neighborhood Hits	230	Shared Neighborhood Hits	37
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

FCRL2_HUMAN
NC score	0.057870 (rank : 441)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	263	Target Neighborhood Hits	251	Shared Neighborhood Hits	31
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

ARHGC_HUMAN
NC score	0.057593 (rank : 442)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	263	Target Neighborhood Hits	351	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

JAM2_MOUSE
NC score	0.057453 (rank : 443)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	263	Target Neighborhood Hits	292	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

FCRL5_HUMAN
NC score	0.056881 (rank : 444)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	263	Target Neighborhood Hits	267	Shared Neighborhood Hits	31
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

CD22_HUMAN
NC score	0.056875 (rank : 445)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	263	Target Neighborhood Hits	365	Shared Neighborhood Hits	37
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

MILK1_MOUSE
NC score	0.056874 (rank : 446)	θ value	0.000461057 (rank : 34)
Query Neighborhood Hits	263	Target Neighborhood Hits	788	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

BLK_MOUSE
NC score	0.056820 (rank : 447)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	263	Target Neighborhood Hits	992	Shared Neighborhood Hits	82
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

SPEG_HUMAN
NC score	0.056717 (rank : 448)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	263	Target Neighborhood Hits	1762	Shared Neighborhood Hits	91
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TIE2_MOUSE
NC score	0.056714 (rank : 449)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	263	Target Neighborhood Hits	1204	Shared Neighborhood Hits	75
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TYRO3_MOUSE
NC score	0.056118 (rank : 450)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	263	Target Neighborhood Hits	1007	Shared Neighborhood Hits	68
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

VSIG2_MOUSE
NC score	0.056088 (rank : 451)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	263	Target Neighborhood Hits	316	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

F107B_HUMAN
NC score	0.055853 (rank : 452)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	263	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

ARHGB_HUMAN
NC score	0.055837 (rank : 453)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	263	Target Neighborhood Hits	375	Shared Neighborhood Hits	27
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

DLG3_HUMAN
NC score	0.055730 (rank : 454)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	263	Target Neighborhood Hits	269	Shared Neighborhood Hits	57
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

ARHG1_MOUSE
NC score	0.055679 (rank : 455)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	263	Target Neighborhood Hits	266	Shared Neighborhood Hits	25
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
NC score	0.055647 (rank : 456)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	263	Target Neighborhood Hits	142	Shared Neighborhood Hits	23
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

BLK_HUMAN
NC score	0.055561 (rank : 457)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	263	Target Neighborhood Hits	994	Shared Neighborhood Hits	89
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

INCE_HUMAN
NC score	0.055559 (rank : 458)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	263	Target Neighborhood Hits	978	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

LZTS2_MOUSE
NC score	0.055423 (rank : 459)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	263	Target Neighborhood Hits	423	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

JIP2_HUMAN
NC score	0.055342 (rank : 460)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	263	Target Neighborhood Hits	288	Shared Neighborhood Hits	52
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

UFO_MOUSE
NC score	0.055179 (rank : 461)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	263	Target Neighborhood Hits	988	Shared Neighborhood Hits	72
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

DLG3_MOUSE
NC score	0.055176 (rank : 462)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	263	Target Neighborhood Hits	274	Shared Neighborhood Hits	57
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

F107B_MOUSE
NC score	0.055101 (rank : 463)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	263	Target Neighborhood Hits	126	Shared Neighborhood Hits	13
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

MERTK_HUMAN
NC score	0.055049 (rank : 464)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	263	Target Neighborhood Hits	988	Shared Neighborhood Hits	63
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

SPEG_MOUSE
NC score	0.054934 (rank : 465)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	263	Target Neighborhood Hits	1959	Shared Neighborhood Hits	89
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CAR10_HUMAN
NC score	0.054930 (rank : 466)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	263	Target Neighborhood Hits	569	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

TXK_MOUSE
NC score	0.054770 (rank : 467)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	263	Target Neighborhood Hits	980	Shared Neighborhood Hits	93
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

CEAM5_HUMAN
NC score	0.054397 (rank : 468)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	263	Target Neighborhood Hits	343	Shared Neighborhood Hits	37
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

LRC45_MOUSE
NC score	0.054241 (rank : 469)	θ value	1.06291 (rank : 162)
Query Neighborhood Hits	263	Target Neighborhood Hits	959	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

ABL1_HUMAN
NC score	0.054026 (rank : 470)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	263	Target Neighborhood Hits	1220	Shared Neighborhood Hits	95
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

LNK_HUMAN
NC score	0.053936 (rank : 471)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	263	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

ABL1_MOUSE
NC score	0.053889 (rank : 472)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	263	Target Neighborhood Hits	1178	Shared Neighborhood Hits	92
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

UFO_HUMAN
NC score	0.053834 (rank : 473)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	263	Target Neighborhood Hits	981	Shared Neighborhood Hits	65
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

DAPP1_MOUSE
NC score	0.053666 (rank : 474)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	263	Target Neighborhood Hits	225	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GOG8A_HUMAN
NC score	0.053614 (rank : 475)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	263	Target Neighborhood Hits	635	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

DLG1_HUMAN
NC score	0.053593 (rank : 476)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	263	Target Neighborhood Hits	290	Shared Neighborhood Hits	56
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

I12R1_HUMAN
NC score	0.053572 (rank : 477)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	263	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

CD45_MOUSE
NC score	0.053529 (rank : 478)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	263	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

RILP_HUMAN
NC score	0.053433 (rank : 479)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	263	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

DAPP1_HUMAN
NC score	0.053428 (rank : 480)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	263	Target Neighborhood Hits	227	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

LCK_HUMAN
NC score	0.053428 (rank : 481)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	263	Target Neighborhood Hits	987	Shared Neighborhood Hits	83
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

PTK6_MOUSE
NC score	0.053264 (rank : 482)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	263	Target Neighborhood Hits	1026	Shared Neighborhood Hits	103
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

LBC_HUMAN
NC score	0.053194 (rank : 483)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	263	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

NRG2_MOUSE
NC score	0.053193 (rank : 484)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	263	Target Neighborhood Hits	392	Shared Neighborhood Hits	39
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

IGS4B_HUMAN
NC score	0.053190 (rank : 485)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	263	Target Neighborhood Hits	305	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

ANKF1_HUMAN
NC score	0.053126 (rank : 486)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	263	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CT116_MOUSE
NC score	0.053016 (rank : 487)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	263	Target Neighborhood Hits	268	Shared Neighborhood Hits	16
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

IGS4B_MOUSE
NC score	0.052947 (rank : 488)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	263	Target Neighborhood Hits	328	Shared Neighborhood Hits	33
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

TRIO_HUMAN
NC score	0.052874 (rank : 489)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	263	Target Neighborhood Hits	1580	Shared Neighborhood Hits	114
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

DLG1_MOUSE
NC score	0.052858 (rank : 490)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	263	Target Neighborhood Hits	285	Shared Neighborhood Hits	61
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

MYLK_MOUSE
NC score	0.052814 (rank : 491)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	263	Target Neighborhood Hits	1489	Shared Neighborhood Hits	77
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

LCK_MOUSE
NC score	0.052699 (rank : 492)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	263	Target Neighborhood Hits	981	Shared Neighborhood Hits	83
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

TEC_HUMAN
NC score	0.052681 (rank : 493)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	263	Target Neighborhood Hits	1006	Shared Neighborhood Hits	94
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

PTK6_HUMAN
NC score	0.052267 (rank : 494)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	263	Target Neighborhood Hits	1020	Shared Neighborhood Hits	106
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

AZI1_HUMAN
NC score	0.052216 (rank : 495)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	263	Target Neighborhood Hits	1000	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

MERTK_MOUSE
NC score	0.052058 (rank : 496)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	263	Target Neighborhood Hits	974	Shared Neighborhood Hits	61
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

SH21B_HUMAN
NC score	0.052050 (rank : 497)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	263	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

P55G_HUMAN
NC score	0.052047 (rank : 498)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	263	Target Neighborhood Hits	451	Shared Neighborhood Hits	46
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

MYLK_HUMAN
NC score	0.052025 (rank : 499)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	263	Target Neighborhood Hits	1328	Shared Neighborhood Hits	68
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

K0552_HUMAN
NC score	0.052015 (rank : 500)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	263	Target Neighborhood Hits	442	Shared Neighborhood Hits	27
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

MFA3L_MOUSE
NC score	0.051774 (rank : 501)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	263	Target Neighborhood Hits	214	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

CEAM1_MOUSE
NC score	0.051771 (rank : 502)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	263	Target Neighborhood Hits	326	Shared Neighborhood Hits	36
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

SHC3_MOUSE
NC score	0.051531 (rank : 503)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	263	Target Neighborhood Hits	151	Shared Neighborhood Hits	29
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

PTPRA_HUMAN
NC score	0.051340 (rank : 504)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	263	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.051311 (rank : 505)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	263	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_MOUSE
NC score	0.051305 (rank : 506)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	263	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

TEC_MOUSE
NC score	0.051243 (rank : 507)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	263	Target Neighborhood Hits	1006	Shared Neighborhood Hits	91
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

PTPRE_HUMAN
NC score	0.051141 (rank : 508)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	263	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

GNRP_MOUSE
NC score	0.051103 (rank : 509)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	263	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

XE7_HUMAN
NC score	0.051051 (rank : 510)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	263	Target Neighborhood Hits	738	Shared Neighborhood Hits	36
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ABL2_HUMAN
NC score	0.051019 (rank : 511)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	263	Target Neighborhood Hits	1045	Shared Neighborhood Hits	82
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

NACAM_MOUSE
NC score	0.050999 (rank : 512)	θ value	1.06291 (rank : 163)
Query Neighborhood Hits	263	Target Neighborhood Hits	1866	Shared Neighborhood Hits	73
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CEA20_HUMAN
NC score	0.050981 (rank : 513)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	263	Target Neighborhood Hits	251	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

DLG4_HUMAN
NC score	0.050939 (rank : 514)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	263	Target Neighborhood Hits	286	Shared Neighborhood Hits	54
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

P55G_MOUSE
NC score	0.050724 (rank : 515)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	263	Target Neighborhood Hits	401	Shared Neighborhood Hits	44
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

JIP1_HUMAN
NC score	0.050601 (rank : 516)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	263	Target Neighborhood Hits	271	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

INCE_MOUSE
NC score	0.050597 (rank : 517)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	263	Target Neighborhood Hits	903	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

I12R1_MOUSE
NC score	0.050024 (rank : 518)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	263	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

TXK_HUMAN
NC score	0.050022 (rank : 519)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	263	Target Neighborhood Hits	971	Shared Neighborhood Hits	86
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

CP250_HUMAN
NC score	0.049958 (rank : 520)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	263	Target Neighborhood Hits	1805	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP250_MOUSE
NC score	0.049759 (rank : 521)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	263	Target Neighborhood Hits	1583	Shared Neighborhood Hits	58
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

REST_HUMAN
NC score	0.049598 (rank : 522)	θ value	0.813845 (rank : 155)
Query Neighborhood Hits	263	Target Neighborhood Hits	1605	Shared Neighborhood Hits	58
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SNX7_MOUSE
NC score	0.048505 (rank : 523)	θ value	0.47712 (rank : 143)
Query Neighborhood Hits	263	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CY18	Gene names	Snx7
Domain Architecture
Description	Sorting nexin-7.

SNX7_HUMAN
NC score	0.048280 (rank : 524)	θ value	0.62314 (rank : 150)
Query Neighborhood Hits	263	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UNH6, Q86U82, Q8WVD4, Q96FW9, Q9Y3Z7	Gene names	SNX7
Domain Architecture
Description	Sorting nexin-7.

ROS_HUMAN
NC score	0.047911 (rank : 525)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	263	Target Neighborhood Hits	907	Shared Neighborhood Hits	71
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

GOGA6_HUMAN
NC score	0.044071 (rank : 526)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	263	Target Neighborhood Hits	1007	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

OPTN_MOUSE
NC score	0.043164 (rank : 527)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	263	Target Neighborhood Hits	1120	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

TRAF3_MOUSE
NC score	0.042589 (rank : 528)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	263	Target Neighborhood Hits	476	Shared Neighborhood Hits	24
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

CAR11_HUMAN
NC score	0.042527 (rank : 529)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	263	Target Neighborhood Hits	690	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

TRAF3_HUMAN
NC score	0.042143 (rank : 530)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	263	Target Neighborhood Hits	463	Shared Neighborhood Hits	22
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

MILK1_HUMAN
NC score	0.041739 (rank : 531)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	263	Target Neighborhood Hits	427	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

EPHAA_HUMAN
NC score	0.040939 (rank : 532)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	263	Target Neighborhood Hits	960	Shared Neighborhood Hits	59
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

KTN1_MOUSE
NC score	0.040237 (rank : 533)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	263	Target Neighborhood Hits	1324	Shared Neighborhood Hits	45
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

S3TC2_MOUSE
NC score	0.039802 (rank : 534)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	263	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

RRBP1_MOUSE
NC score	0.039537 (rank : 535)	θ value	1.81305 (rank : 178)
Query Neighborhood Hits	263	Target Neighborhood Hits	1650	Shared Neighborhood Hits	58
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TARA_MOUSE
NC score	0.038032 (rank : 536)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	263	Target Neighborhood Hits	1133	Shared Neighborhood Hits	49
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

KTN1_HUMAN
NC score	0.036654 (rank : 537)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	263	Target Neighborhood Hits	1197	Shared Neighborhood Hits	40
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

HUCE1_MOUSE
NC score	0.036098 (rank : 538)	θ value	0.47712 (rank : 140)
Query Neighborhood Hits	263	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DB85, Q8BHW3	Gene names
Domain Architecture	No domain graphic available
Description	Cerebral protein 1 homolog.

REST_MOUSE
NC score	0.035791 (rank : 539)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	263	Target Neighborhood Hits	1506	Shared Neighborhood Hits	50
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

PDCD7_HUMAN
NC score	0.033631 (rank : 540)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	263	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

MYH3_HUMAN
NC score	0.032625 (rank : 541)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	263	Target Neighborhood Hits	1660	Shared Neighborhood Hits	63
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TEX9_MOUSE
NC score	0.032602 (rank : 542)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	263	Target Neighborhood Hits	581	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

EEA1_MOUSE
NC score	0.032199 (rank : 543)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	263	Target Neighborhood Hits	1637	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

PDCD7_MOUSE
NC score	0.030618 (rank : 544)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	263	Target Neighborhood Hits	214	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

MYO5C_HUMAN
NC score	0.030219 (rank : 545)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	263	Target Neighborhood Hits	1206	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYH6_MOUSE
NC score	0.029724 (rank : 546)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	263	Target Neighborhood Hits	1501	Shared Neighborhood Hits	54
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NCOR2_HUMAN
NC score	0.029145 (rank : 547)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	263	Target Neighborhood Hits	870	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

RGS3_MOUSE
NC score	0.028644 (rank : 548)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	263	Target Neighborhood Hits	1621	Shared Neighborhood Hits	61
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CF182_HUMAN
NC score	0.028565 (rank : 549)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	263	Target Neighborhood Hits	474	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

MUC1_HUMAN
NC score	0.026858 (rank : 550)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	263	Target Neighborhood Hits	975	Shared Neighborhood Hits	39
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

YETS2_HUMAN
NC score	0.025766 (rank : 551)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	263	Target Neighborhood Hits	212	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

SNPC4_MOUSE
NC score	0.021090 (rank : 552)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	263	Target Neighborhood Hits	237	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

ARTN_HUMAN
NC score	0.021048 (rank : 553)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	263	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

VDP_HUMAN
NC score	0.020786 (rank : 554)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	263	Target Neighborhood Hits	645	Shared Neighborhood Hits	29
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

TTBK1_HUMAN
NC score	0.020409 (rank : 555)	θ value	0.813845 (rank : 158)
Query Neighborhood Hits	263	Target Neighborhood Hits	1058	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

K0256_HUMAN
NC score	0.020118 (rank : 556)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	263	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q93073, Q8N767	Gene names	KIAA0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

DTNB_MOUSE
NC score	0.019746 (rank : 557)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	263	Target Neighborhood Hits	263	Shared Neighborhood Hits	19
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

ABCBB_HUMAN
NC score	0.019601 (rank : 558)	θ value	0.125558 (rank : 98)
Query Neighborhood Hits	263	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

K0256_MOUSE
NC score	0.019379 (rank : 559)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	263	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

ABCBB_MOUSE
NC score	0.018709 (rank : 560)	θ value	0.279714 (rank : 123)
Query Neighborhood Hits	263	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

CIZ1_HUMAN
NC score	0.017597 (rank : 561)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	263	Target Neighborhood Hits	359	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

DUS3L_MOUSE
NC score	0.016817 (rank : 562)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	263	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XI1, Q3TZQ1, Q7TT12	Gene names	Dus3l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

LRRK2_MOUSE
NC score	0.016751 (rank : 563)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	263	Target Neighborhood Hits	1359	Shared Neighborhood Hits	25
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

SIRT1_MOUSE
NC score	0.015979 (rank : 564)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	263	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

PPRB_MOUSE
NC score	0.015422 (rank : 565)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	263	Target Neighborhood Hits	354	Shared Neighborhood Hits	19
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

GAB2_MOUSE
NC score	0.015285 (rank : 566)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	263	Target Neighborhood Hits	220	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

SFR16_HUMAN
NC score	0.015181 (rank : 567)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	263	Target Neighborhood Hits	178	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N2M8, O96026, Q6UW71, Q96DX2	Gene names	SFRS16, SWAP2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2).

HDAC5_HUMAN
NC score	0.015122 (rank : 568)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	263	Target Neighborhood Hits	353	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

AHTF1_MOUSE
NC score	0.014538 (rank : 569)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	263	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CBP_MOUSE
NC score	0.014089 (rank : 570)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	263	Target Neighborhood Hits	1051	Shared Neighborhood Hits	38
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CNKR1_HUMAN
NC score	0.014066 (rank : 571)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	263	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CO5A2_HUMAN
NC score	0.014005 (rank : 572)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	263	Target Neighborhood Hits	760	Shared Neighborhood Hits	18
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

K1967_MOUSE
NC score	0.013715 (rank : 573)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	263	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

PITM1_HUMAN
NC score	0.013330 (rank : 574)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	263	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

REXO1_MOUSE
NC score	0.013049 (rank : 575)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	263	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

TBCD4_HUMAN
NC score	0.012521 (rank : 576)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	263	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TR240_HUMAN
NC score	0.012298 (rank : 577)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	263	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

HDAC7_MOUSE
NC score	0.010738 (rank : 578)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	263	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

AKA12_HUMAN
NC score	0.010636 (rank : 579)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	263	Target Neighborhood Hits	825	Shared Neighborhood Hits	27
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

NOC2L_HUMAN
NC score	0.009794 (rank : 580)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	263	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3T9, Q5SVA3, Q9BTN6	Gene names	NOC2L
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

NFIX_MOUSE
NC score	0.009742 (rank : 581)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	263	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P70257, O08519, P70258, Q64192, Q99L78, Q9R1G2	Gene names	Nfix
Domain Architecture
Description	Nuclear factor 1 X-type (Nuclear factor 1/X) (NF1-X) (NFI-X) (NF-I/X) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIX_HUMAN
NC score	0.009718 (rank : 582)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	263	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q14938, O60413, Q12859, Q13050, Q13052, Q9UPH1, Q9Y6R8	Gene names	NFIX
Domain Architecture
Description	Nuclear factor 1 X-type (Nuclear factor 1/X) (NF1-X) (NFI-X) (NF-I/X) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

ST5_HUMAN
NC score	0.009341 (rank : 583)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	263	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

CBL_MOUSE
NC score	0.009007 (rank : 584)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	263	Target Neighborhood Hits	426	Shared Neighborhood Hits	16
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

GASP1_HUMAN
NC score	0.008445 (rank : 585)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	263	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JY77, O43168, Q96LA1	Gene names	GPRASP1, GASP, KIAA0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

FOXP3_MOUSE
NC score	0.007812 (rank : 586)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	263	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JB6	Gene names	Foxp3
Domain Architecture
Description	Forkhead box protein P3 (Scurfin).

TCAL5_HUMAN
NC score	0.007380 (rank : 587)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	263	Target Neighborhood Hits	806	Shared Neighborhood Hits	23
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

FOXP3_HUMAN
NC score	0.006561 (rank : 588)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	263	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZS1, O60827, Q4ZH51	Gene names	FOXP3, IPEX
Domain Architecture
Description	Forkhead box protein P3 (Scurfin).

ELK1_MOUSE
NC score	0.005262 (rank : 589)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	263	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

SEM6D_MOUSE
NC score	0.003637 (rank : 590)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	263	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

ZEP1_HUMAN
NC score	-0.001545 (rank : 591)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	263	Target Neighborhood Hits	1036	Shared Neighborhood Hits	13
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

MZF1_HUMAN
NC score	-0.007073 (rank : 592)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	263	Target Neighborhood Hits	753	Shared Neighborhood Hits	4
SwissProt Accessions	P28698, Q9NRY0, Q9UBW2	Gene names	MZF1, MZF, ZNF42, ZSCAN6
Domain Architecture
Description	Myeloid zinc finger 1 (MZF-1) (Zinc finger protein 42) (Zinc finger and SCAN domain-containing protein 6).