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Network neighborhood for query Sequence : BI2L1_HUMAN

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BI2L1_HUMAN
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BI2L1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	156	Target Neighborhood Hits	156	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BI2L1_MOUSE
θ value	0 (rank : 2)	NC score	0.960716 (rank : 2)
Query Neighborhood Hits	156	Target Neighborhood Hits	197	Shared Neighborhood Hits	97
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BAIP2_HUMAN
θ value	9.96626e-108 (rank : 3)	NC score	0.897188 (rank : 4)
Query Neighborhood Hits	156	Target Neighborhood Hits	192	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	4.33309e-103 (rank : 4)	NC score	0.900856 (rank : 3)
Query Neighborhood Hits	156	Target Neighborhood Hits	185	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

MTSS1_HUMAN
θ value	1.99992e-07 (rank : 5)	NC score	0.312620 (rank : 5)
Query Neighborhood Hits	156	Target Neighborhood Hits	504	Shared Neighborhood Hits	24
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

ITSN1_MOUSE
θ value	3.77169e-06 (rank : 6)	NC score	0.225678 (rank : 9)
Query Neighborhood Hits	156	Target Neighborhood Hits	1669	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MTSS1_MOUSE
θ value	1.43324e-05 (rank : 7)	NC score	0.279567 (rank : 6)
Query Neighborhood Hits	156	Target Neighborhood Hits	592	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

ITSN2_MOUSE
θ value	1.87187e-05 (rank : 8)	NC score	0.227023 (rank : 8)
Query Neighborhood Hits	156	Target Neighborhood Hits	1371	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITSN2_HUMAN
θ value	0.000158464 (rank : 9)	NC score	0.222885 (rank : 10)
Query Neighborhood Hits	156	Target Neighborhood Hits	1173	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN1_HUMAN
θ value	0.000270298 (rank : 10)	NC score	0.220196 (rank : 11)
Query Neighborhood Hits	156	Target Neighborhood Hits	1757	Shared Neighborhood Hits	135
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ARHG6_HUMAN
θ value	0.00869519 (rank : 11)	NC score	0.207713 (rank : 15)
Query Neighborhood Hits	156	Target Neighborhood Hits	376	Shared Neighborhood Hits	82
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG7_MOUSE
θ value	0.00869519 (rank : 12)	NC score	0.201614 (rank : 17)
Query Neighborhood Hits	156	Target Neighborhood Hits	396	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG9_HUMAN
θ value	0.00869519 (rank : 13)	NC score	0.192538 (rank : 25)
Query Neighborhood Hits	156	Target Neighborhood Hits	235	Shared Neighborhood Hits	61
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

NGEF_MOUSE
θ value	0.00869519 (rank : 14)	NC score	0.195039 (rank : 20)
Query Neighborhood Hits	156	Target Neighborhood Hits	228	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

DDEF1_MOUSE
θ value	0.0113563 (rank : 15)	NC score	0.129217 (rank : 55)
Query Neighborhood Hits	156	Target Neighborhood Hits	592	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DNMBP_MOUSE
θ value	0.0113563 (rank : 16)	NC score	0.185217 (rank : 32)
Query Neighborhood Hits	156	Target Neighborhood Hits	435	Shared Neighborhood Hits	77
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

NCF4_MOUSE
θ value	0.0113563 (rank : 17)	NC score	0.234425 (rank : 7)
Query Neighborhood Hits	156	Target Neighborhood Hits	177	Shared Neighborhood Hits	56
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

PACN3_HUMAN
θ value	0.0113563 (rank : 18)	NC score	0.190861 (rank : 26)
Query Neighborhood Hits	156	Target Neighborhood Hits	385	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	0.0113563 (rank : 19)	NC score	0.195888 (rank : 19)
Query Neighborhood Hits	156	Target Neighborhood Hits	380	Shared Neighborhood Hits	84
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

CN145_HUMAN
θ value	0.0148317 (rank : 20)	NC score	0.092173 (rank : 122)
Query Neighborhood Hits	156	Target Neighborhood Hits	1196	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

NGEF_HUMAN
θ value	0.0148317 (rank : 21)	NC score	0.187984 (rank : 29)
Query Neighborhood Hits	156	Target Neighborhood Hits	166	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHG7_HUMAN
θ value	0.0193708 (rank : 22)	NC score	0.192582 (rank : 24)
Query Neighborhood Hits	156	Target Neighborhood Hits	347	Shared Neighborhood Hits	71
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG6_MOUSE
θ value	0.0252991 (rank : 23)	NC score	0.202387 (rank : 16)
Query Neighborhood Hits	156	Target Neighborhood Hits	394	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

LASP1_HUMAN
θ value	0.0252991 (rank : 24)	NC score	0.185479 (rank : 31)
Query Neighborhood Hits	156	Target Neighborhood Hits	293	Shared Neighborhood Hits	61
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	0.0252991 (rank : 25)	NC score	0.185132 (rank : 33)
Query Neighborhood Hits	156	Target Neighborhood Hits	297	Shared Neighborhood Hits	61
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ARHGG_HUMAN
θ value	0.0330416 (rank : 26)	NC score	0.196429 (rank : 18)
Query Neighborhood Hits	156	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

SH3K1_HUMAN
θ value	0.0330416 (rank : 27)	NC score	0.219644 (rank : 12)
Query Neighborhood Hits	156	Target Neighborhood Hits	341	Shared Neighborhood Hits	70
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	0.0330416 (rank : 28)	NC score	0.217428 (rank : 13)
Query Neighborhood Hits	156	Target Neighborhood Hits	332	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

ARHG9_MOUSE
θ value	0.0431538 (rank : 29)	NC score	0.192952 (rank : 23)
Query Neighborhood Hits	156	Target Neighborhood Hits	234	Shared Neighborhood Hits	60
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

CCD46_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.078091 (rank : 160)
Query Neighborhood Hits	156	Target Neighborhood Hits	1430	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

NCF4_HUMAN
θ value	0.0431538 (rank : 31)	NC score	0.210443 (rank : 14)
Query Neighborhood Hits	156	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

PACN1_HUMAN
θ value	0.0431538 (rank : 32)	NC score	0.195013 (rank : 21)
Query Neighborhood Hits	156	Target Neighborhood Hits	320	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

SYCP1_HUMAN
θ value	0.0431538 (rank : 33)	NC score	0.082981 (rank : 149)
Query Neighborhood Hits	156	Target Neighborhood Hits	1313	Shared Neighborhood Hits	69
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ARHGG_MOUSE
θ value	0.0563607 (rank : 34)	NC score	0.194521 (rank : 22)
Query Neighborhood Hits	156	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CD2AP_MOUSE
θ value	0.0563607 (rank : 35)	NC score	0.190148 (rank : 27)
Query Neighborhood Hits	156	Target Neighborhood Hits	336	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

SMC1A_MOUSE
θ value	0.0736092 (rank : 36)	NC score	0.102157 (rank : 95)
Query Neighborhood Hits	156	Target Neighborhood Hits	1384	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

CASP_HUMAN
θ value	0.0961366 (rank : 37)	NC score	0.093928 (rank : 114)
Query Neighborhood Hits	156	Target Neighborhood Hits	1131	Shared Neighborhood Hits	68
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	0.0961366 (rank : 38)	NC score	0.089824 (rank : 128)
Query Neighborhood Hits	156	Target Neighborhood Hits	1574	Shared Neighborhood Hits	69
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

MAP9_MOUSE
θ value	0.0961366 (rank : 39)	NC score	0.098765 (rank : 104)
Query Neighborhood Hits	156	Target Neighborhood Hits	529	Shared Neighborhood Hits	48
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

SMC1A_HUMAN
θ value	0.0961366 (rank : 40)	NC score	0.104010 (rank : 92)
Query Neighborhood Hits	156	Target Neighborhood Hits	1346	Shared Neighborhood Hits	82
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC2_HUMAN
θ value	0.0961366 (rank : 41)	NC score	0.101614 (rank : 96)
Query Neighborhood Hits	156	Target Neighborhood Hits	1405	Shared Neighborhood Hits	75
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

GCC2_HUMAN
θ value	0.163984 (rank : 42)	NC score	0.075525 (rank : 167)
Query Neighborhood Hits	156	Target Neighborhood Hits	1558	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.163984 (rank : 43)	NC score	0.075628 (rank : 166)
Query Neighborhood Hits	156	Target Neighborhood Hits	1559	Shared Neighborhood Hits	80
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

VAV_MOUSE
θ value	0.163984 (rank : 44)	NC score	0.161363 (rank : 40)
Query Neighborhood Hits	156	Target Neighborhood Hits	430	Shared Neighborhood Hits	68
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

DDEF2_MOUSE
θ value	0.21417 (rank : 45)	NC score	0.107072 (rank : 88)
Query Neighborhood Hits	156	Target Neighborhood Hits	625	Shared Neighborhood Hits	69
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SNX9_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.160205 (rank : 42)
Query Neighborhood Hits	156	Target Neighborhood Hits	148	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

ANKS6_MOUSE
θ value	0.279714 (rank : 47)	NC score	0.025282 (rank : 517)
Query Neighborhood Hits	156	Target Neighborhood Hits	435	Shared Neighborhood Hits	13
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

CASP_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.092477 (rank : 120)
Query Neighborhood Hits	156	Target Neighborhood Hits	1152	Shared Neighborhood Hits	68
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CF055_MOUSE
θ value	0.279714 (rank : 49)	NC score	0.048379 (rank : 502)
Query Neighborhood Hits	156	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

CUTL1_MOUSE
θ value	0.279714 (rank : 50)	NC score	0.090840 (rank : 126)
Query Neighborhood Hits	156	Target Neighborhood Hits	1620	Shared Neighborhood Hits	69
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TACC2_MOUSE
θ value	0.279714 (rank : 51)	NC score	0.094019 (rank : 112)
Query Neighborhood Hits	156	Target Neighborhood Hits	774	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

VAV3_HUMAN
θ value	0.279714 (rank : 52)	NC score	0.128449 (rank : 57)
Query Neighborhood Hits	156	Target Neighborhood Hits	398	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

XE7_HUMAN
θ value	0.279714 (rank : 53)	NC score	0.088269 (rank : 136)
Query Neighborhood Hits	156	Target Neighborhood Hits	738	Shared Neighborhood Hits	61
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

VAV_HUMAN
θ value	0.365318 (rank : 54)	NC score	0.159483 (rank : 43)
Query Neighborhood Hits	156	Target Neighborhood Hits	452	Shared Neighborhood Hits	71
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ANKS6_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.024555 (rank : 518)
Query Neighborhood Hits	156	Target Neighborhood Hits	411	Shared Neighborhood Hits	10
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR26_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.061632 (rank : 284)
Query Neighborhood Hits	156	Target Neighborhood Hits	1614	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MYO7A_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.044056 (rank : 506)
Query Neighborhood Hits	156	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.045520 (rank : 505)
Query Neighborhood Hits	156	Target Neighborhood Hits	235	Shared Neighborhood Hits	26
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

NCF1_MOUSE
θ value	0.47712 (rank : 59)	NC score	0.183218 (rank : 34)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	58
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

LYN_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.018864 (rank : 525)
Query Neighborhood Hits	156	Target Neighborhood Hits	1022	Shared Neighborhood Hits	53
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

PACN1_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.180475 (rank : 36)
Query Neighborhood Hits	156	Target Neighborhood Hits	283	Shared Neighborhood Hits	76
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

SNX9_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.139902 (rank : 53)
Query Neighborhood Hits	156	Target Neighborhood Hits	141	Shared Neighborhood Hits	43
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

VAV2_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.156107 (rank : 46)
Query Neighborhood Hits	156	Target Neighborhood Hits	453	Shared Neighborhood Hits	68
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	0.62314 (rank : 64)	NC score	0.153682 (rank : 48)
Query Neighborhood Hits	156	Target Neighborhood Hits	456	Shared Neighborhood Hits	68
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_MOUSE
θ value	0.62314 (rank : 65)	NC score	0.125749 (rank : 59)
Query Neighborhood Hits	156	Target Neighborhood Hits	404	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

RHG26_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.095860 (rank : 107)
Query Neighborhood Hits	156	Target Neighborhood Hits	281	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SMC2_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.114228 (rank : 71)
Query Neighborhood Hits	156	Target Neighborhood Hits	1131	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

STAC_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.128025 (rank : 58)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	60
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CIP4_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.097253 (rank : 105)
Query Neighborhood Hits	156	Target Neighborhood Hits	374	Shared Neighborhood Hits	52
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

FYCO1_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.066165 (rank : 224)
Query Neighborhood Hits	156	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

RIMB2_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.095666 (rank : 109)
Query Neighborhood Hits	156	Target Neighborhood Hits	263	Shared Neighborhood Hits	48
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SAS6_MOUSE
θ value	1.06291 (rank : 72)	NC score	0.066535 (rank : 219)
Query Neighborhood Hits	156	Target Neighborhood Hits	931	Shared Neighborhood Hits	59
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

CCD46_MOUSE
θ value	1.38821 (rank : 73)	NC score	0.072746 (rank : 177)
Query Neighborhood Hits	156	Target Neighborhood Hits	1405	Shared Neighborhood Hits	75
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

MYH4_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.050926 (rank : 480)
Query Neighborhood Hits	156	Target Neighborhood Hits	1377	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

PACN2_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.185536 (rank : 30)
Query Neighborhood Hits	156	Target Neighborhood Hits	382	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PAPOG_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.021099 (rank : 524)
Query Neighborhood Hits	156	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

RUFY2_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.057789 (rank : 356)
Query Neighborhood Hits	156	Target Neighborhood Hits	1208	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SF3A1_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.052440 (rank : 456)
Query Neighborhood Hits	156	Target Neighborhood Hits	199	Shared Neighborhood Hits	8
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A1_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.051395 (rank : 467)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

STIM1_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.089225 (rank : 131)
Query Neighborhood Hits	156	Target Neighborhood Hits	665	Shared Neighborhood Hits	58
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.089086 (rank : 132)
Query Neighborhood Hits	156	Target Neighborhood Hits	660	Shared Neighborhood Hits	56
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TPR_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.067907 (rank : 206)
Query Neighborhood Hits	156	Target Neighborhood Hits	1921	Shared Neighborhood Hits	78
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ARHG5_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.147814 (rank : 51)
Query Neighborhood Hits	156	Target Neighborhood Hits	172	Shared Neighborhood Hits	49
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

BPAEA_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.048289 (rank : 503)
Query Neighborhood Hits	156	Target Neighborhood Hits	1369	Shared Neighborhood Hits	65
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRD4_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.035785 (rank : 510)
Query Neighborhood Hits	156	Target Neighborhood Hits	845	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MDC1_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.037996 (rank : 508)
Query Neighborhood Hits	156	Target Neighborhood Hits	1446	Shared Neighborhood Hits	44
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PACN2_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.188935 (rank : 28)
Query Neighborhood Hits	156	Target Neighborhood Hits	339	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SPN90_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.055890 (rank : 392)
Query Neighborhood Hits	156	Target Neighborhood Hits	157	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

TCGAP_MOUSE
θ value	1.81305 (rank : 89)	NC score	0.063871 (rank : 251)
Query Neighborhood Hits	156	Target Neighborhood Hits	409	Shared Neighborhood Hits	49
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ARHG4_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.153992 (rank : 47)
Query Neighborhood Hits	156	Target Neighborhood Hits	185	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

BAP29_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.045760 (rank : 504)
Query Neighborhood Hits	156	Target Neighborhood Hits	285	Shared Neighborhood Hits	33
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

BIN1_HUMAN
θ value	2.36792 (rank : 92)	NC score	0.066725 (rank : 217)
Query Neighborhood Hits	156	Target Neighborhood Hits	335	Shared Neighborhood Hits	52
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CD2AP_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.180938 (rank : 35)
Query Neighborhood Hits	156	Target Neighborhood Hits	315	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CP135_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.068560 (rank : 203)
Query Neighborhood Hits	156	Target Neighborhood Hits	1278	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MAP9_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.093309 (rank : 115)
Query Neighborhood Hits	156	Target Neighborhood Hits	518	Shared Neighborhood Hits	50
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NCF1_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.159458 (rank : 44)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	55
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

RABE1_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.073277 (rank : 174)
Query Neighborhood Hits	156	Target Neighborhood Hits	1104	Shared Neighborhood Hits	66
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

ARHG4_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.165683 (rank : 38)
Query Neighborhood Hits	156	Target Neighborhood Hits	242	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CAN1_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.007491 (rank : 535)
Query Neighborhood Hits	156	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

CENPE_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.061376 (rank : 288)
Query Neighborhood Hits	156	Target Neighborhood Hits	2060	Shared Neighborhood Hits	87
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

K0690_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.034496 (rank : 511)
Query Neighborhood Hits	156	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

RABE1_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.070315 (rank : 191)
Query Neighborhood Hits	156	Target Neighborhood Hits	1105	Shared Neighborhood Hits	67
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

SH3G2_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.123349 (rank : 63)
Query Neighborhood Hits	156	Target Neighborhood Hits	324	Shared Neighborhood Hits	71
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G2_MOUSE
θ value	3.0926 (rank : 104)	NC score	0.125279 (rank : 60)
Query Neighborhood Hits	156	Target Neighborhood Hits	319	Shared Neighborhood Hits	75
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

TACC2_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.077703 (rank : 161)
Query Neighborhood Hits	156	Target Neighborhood Hits	856	Shared Neighborhood Hits	64
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

WASIP_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.037796 (rank : 509)
Query Neighborhood Hits	156	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.040369 (rank : 507)
Query Neighborhood Hits	156	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CING_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.066115 (rank : 227)
Query Neighborhood Hits	156	Target Neighborhood Hits	1432	Shared Neighborhood Hits	70
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

DDEF2_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.099915 (rank : 100)
Query Neighborhood Hits	156	Target Neighborhood Hits	599	Shared Neighborhood Hits	77
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

IF4G3_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.022265 (rank : 521)
Query Neighborhood Hits	156	Target Neighborhood Hits	279	Shared Neighborhood Hits	16
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

NCK1_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.128943 (rank : 56)
Query Neighborhood Hits	156	Target Neighborhood Hits	312	Shared Neighborhood Hits	68
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.122385 (rank : 64)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NMNA2_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.029246 (rank : 514)
Query Neighborhood Hits	156	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZQ4, O75067, Q5T1Q3, Q8WU99, Q96QW1	Gene names	NMNAT2, C1orf15, KIAA0479
Domain Architecture
Description	Nicotinamide mononucleotide adenylyltransferase 2 (EC 2.7.7.1) (NMN adenylyltransferase 2).

PRAX_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.022645 (rank : 520)
Query Neighborhood Hits	156	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PREP_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.021325 (rank : 523)
Query Neighborhood Hits	156	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JRX3, O95204, Q2M2G6, Q4VBR1, Q5JRW7, Q7L5Z7, Q9BSI6, Q9BVJ5, Q9UPP8	Gene names	PITRM1, KIAA1104, MP1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (hPreP) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1).

SM1L2_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.083734 (rank : 146)
Query Neighborhood Hits	156	Target Neighborhood Hits	1019	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SPTA2_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.079132 (rank : 158)
Query Neighborhood Hits	156	Target Neighborhood Hits	888	Shared Neighborhood Hits	104
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

TCGAP_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.054657 (rank : 420)
Query Neighborhood Hits	156	Target Neighborhood Hits	872	Shared Neighborhood Hits	55
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ANR21_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.030595 (rank : 512)
Query Neighborhood Hits	156	Target Neighborhood Hits	864	Shared Neighborhood Hits	55
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

EBP2_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.058499 (rank : 346)
Query Neighborhood Hits	156	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	Q99848, Q96A66	Gene names	EBNA1BP2, EBP2
Domain Architecture
Description	Probable rRNA-processing protein EBP2 (EBNA1-binding protein 2) (Nucleolar protein p40).

GFC1_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.017997 (rank : 529)
Query Neighborhood Hits	156	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

GOGA2_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.068639 (rank : 202)
Query Neighborhood Hits	156	Target Neighborhood Hits	944	Shared Neighborhood Hits	63
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.060279 (rank : 309)
Query Neighborhood Hits	156	Target Neighborhood Hits	1437	Shared Neighborhood Hits	67
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

HCK_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.018640 (rank : 527)
Query Neighborhood Hits	156	Target Neighborhood Hits	1035	Shared Neighborhood Hits	55
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.018687 (rank : 526)
Query Neighborhood Hits	156	Target Neighborhood Hits	1029	Shared Neighborhood Hits	55
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

MYH6_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.056497 (rank : 380)
Query Neighborhood Hits	156	Target Neighborhood Hits	1501	Shared Neighborhood Hits	79
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NEBL_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.148477 (rank : 50)
Query Neighborhood Hits	156	Target Neighborhood Hits	457	Shared Neighborhood Hits	90
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEST_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.053057 (rank : 442)
Query Neighborhood Hits	156	Target Neighborhood Hits	1305	Shared Neighborhood Hits	60
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NMNA2_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.021711 (rank : 522)
Query Neighborhood Hits	156	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BNJ3	Gene names	Nmnat2, Kiaa0479
Domain Architecture
Description	Nicotinamide mononucleotide adenylyltransferase 2 (EC 2.7.7.1) (NMN adenylyltransferase 2).

POT15_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.028993 (rank : 515)
Query Neighborhood Hits	156	Target Neighborhood Hits	893	Shared Neighborhood Hits	49
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PRAX_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.022979 (rank : 519)
Query Neighborhood Hits	156	Target Neighborhood Hits	215	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

SRBS1_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.167556 (rank : 37)
Query Neighborhood Hits	156	Target Neighborhood Hits	396	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAC_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.114154 (rank : 72)
Query Neighborhood Hits	156	Target Neighborhood Hits	268	Shared Neighborhood Hits	58
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

TFE3_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.018624 (rank : 528)
Query Neighborhood Hits	156	Target Neighborhood Hits	190	Shared Neighborhood Hits	18
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

UACA_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.062097 (rank : 276)
Query Neighborhood Hits	156	Target Neighborhood Hits	1622	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

FEZ1_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.028574 (rank : 516)
Query Neighborhood Hits	156	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K0X8	Gene names	Fez1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

JHD2B_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.009046 (rank : 534)
Query Neighborhood Hits	156	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

M4K4_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.016509 (rank : 531)
Query Neighborhood Hits	156	Target Neighborhood Hits	1589	Shared Neighborhood Hits	66
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MYH10_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.054825 (rank : 417)
Query Neighborhood Hits	156	Target Neighborhood Hits	1612	Shared Neighborhood Hits	80
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.054852 (rank : 415)
Query Neighborhood Hits	156	Target Neighborhood Hits	1829	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NIN_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.060406 (rank : 304)
Query Neighborhood Hits	156	Target Neighborhood Hits	1416	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

ROCK2_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.030305 (rank : 513)
Query Neighborhood Hits	156	Target Neighborhood Hits	2073	Shared Neighborhood Hits	71
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

UBF1_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.015047 (rank : 532)
Query Neighborhood Hits	156	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

EP400_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.009654 (rank : 533)
Query Neighborhood Hits	156	Target Neighborhood Hits	556	Shared Neighborhood Hits	13
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FLIP1_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.067176 (rank : 213)
Query Neighborhood Hits	156	Target Neighborhood Hits	1405	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

HIP1_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.058604 (rank : 345)
Query Neighborhood Hits	156	Target Neighborhood Hits	1016	Shared Neighborhood Hits	65
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

K6PL_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.006308 (rank : 536)
Query Neighborhood Hits	156	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P17858, Q96A64, Q96IH4, Q9BR91	Gene names	PFKL
Domain Architecture
Description	6-phosphofructokinase, liver type (EC 2.7.1.11) (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme B) (PFK-B).

M3K13_HUMAN
θ value	8.99809 (rank : 148)	NC score	-0.000806 (rank : 538)
Query Neighborhood Hits	156	Target Neighborhood Hits	911	Shared Neighborhood Hits	10
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M4K4_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.016873 (rank : 530)
Query Neighborhood Hits	156	Target Neighborhood Hits	1560	Shared Neighborhood Hits	63
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MYH10_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.054542 (rank : 425)
Query Neighborhood Hits	156	Target Neighborhood Hits	1620	Shared Neighborhood Hits	81
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RIMB1_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.093938 (rank : 113)
Query Neighborhood Hits	156	Target Neighborhood Hits	1479	Shared Neighborhood Hits	102
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.081080 (rank : 151)
Query Neighborhood Hits	156	Target Neighborhood Hits	1376	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RRBP1_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.055012 (rank : 411)
Query Neighborhood Hits	156	Target Neighborhood Hits	1650	Shared Neighborhood Hits	71
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SCYL2_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.004981 (rank : 537)
Query Neighborhood Hits	156	Target Neighborhood Hits	632	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

SM1L2_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.081077 (rank : 152)
Query Neighborhood Hits	156	Target Neighborhood Hits	918	Shared Neighborhood Hits	65
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

STS1_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.059692 (rank : 328)
Query Neighborhood Hits	156	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

ABI1_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.105839 (rank : 89)
Query Neighborhood Hits	156	Target Neighborhood Hits	257	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.110813 (rank : 79)
Query Neighborhood Hits	156	Target Neighborhood Hits	246	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.114541 (rank : 70)
Query Neighborhood Hits	156	Target Neighborhood Hits	350	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.115121 (rank : 69)
Query Neighborhood Hits	156	Target Neighborhood Hits	266	Shared Neighborhood Hits	60
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.099953 (rank : 99)
Query Neighborhood Hits	156	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.092912 (rank : 119)
Query Neighborhood Hits	156	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AHI1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.081019 (rank : 153)
Query Neighborhood Hits	156	Target Neighborhood Hits	537	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.078946 (rank : 159)
Query Neighborhood Hits	156	Target Neighborhood Hits	496	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

AKAP9_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.061969 (rank : 277)
Query Neighborhood Hits	156	Target Neighborhood Hits	1710	Shared Neighborhood Hits	77
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

AL2SB_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.050436 (rank : 493)
Query Neighborhood Hits	156	Target Neighborhood Hits	294	Shared Neighborhood Hits	42
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

AMPH_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.060469 (rank : 302)
Query Neighborhood Hits	156	Target Neighborhood Hits	455	Shared Neighborhood Hits	56
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.051207 (rank : 471)
Query Neighborhood Hits	156	Target Neighborhood Hits	291	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANM2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.060102 (rank : 317)
Query Neighborhood Hits	156	Target Neighborhood Hits	175	Shared Neighborhood Hits	45
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.056786 (rank : 374)
Query Neighborhood Hits	156	Target Neighborhood Hits	175	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANR18_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.052699 (rank : 448)
Query Neighborhood Hits	156	Target Neighborhood Hits	1106	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR26_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.054620 (rank : 422)
Query Neighborhood Hits	156	Target Neighborhood Hits	1554	Shared Neighborhood Hits	66
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ARHG1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.087659 (rank : 137)
Query Neighborhood Hits	156	Target Neighborhood Hits	176	Shared Neighborhood Hits	22
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.076149 (rank : 165)
Query Neighborhood Hits	156	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.072628 (rank : 178)
Query Neighborhood Hits	156	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.073683 (rank : 171)
Query Neighborhood Hits	156	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.111773 (rank : 75)
Query Neighborhood Hits	156	Target Neighborhood Hits	82	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.111310 (rank : 78)
Query Neighborhood Hits	156	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG8_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.105585 (rank : 90)
Query Neighborhood Hits	156	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.113531 (rank : 73)
Query Neighborhood Hits	156	Target Neighborhood Hits	79	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGA_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.088662 (rank : 134)
Query Neighborhood Hits	156	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.086643 (rank : 141)
Query Neighborhood Hits	156	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.085740 (rank : 145)
Query Neighborhood Hits	156	Target Neighborhood Hits	375	Shared Neighborhood Hits	27
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.086592 (rank : 142)
Query Neighborhood Hits	156	Target Neighborhood Hits	351	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.086221 (rank : 143)
Query Neighborhood Hits	156	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.112530 (rank : 74)
Query Neighborhood Hits	156	Target Neighborhood Hits	214	Shared Neighborhood Hits	23
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ASPP1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.064412 (rank : 244)
Query Neighborhood Hits	156	Target Neighborhood Hits	956	Shared Neighborhood Hits	95
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.064695 (rank : 243)
Query Neighborhood Hits	156	Target Neighborhood Hits	1244	Shared Neighborhood Hits	101
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.064732 (rank : 242)
Query Neighborhood Hits	156	Target Neighborhood Hits	1156	Shared Neighborhood Hits	98
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

AZI1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.064161 (rank : 247)
Query Neighborhood Hits	156	Target Neighborhood Hits	1000	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.062148 (rank : 274)
Query Neighborhood Hits	156	Target Neighborhood Hits	990	Shared Neighborhood Hits	70
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BCAR1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.069256 (rank : 199)
Query Neighborhood Hits	156	Target Neighborhood Hits	554	Shared Neighborhood Hits	62
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.070293 (rank : 192)
Query Neighborhood Hits	156	Target Neighborhood Hits	438	Shared Neighborhood Hits	63
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCR_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.054732 (rank : 418)
Query Neighborhood Hits	156	Target Neighborhood Hits	204	Shared Neighborhood Hits	24
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BICD2_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.050940 (rank : 479)
Query Neighborhood Hits	156	Target Neighborhood Hits	856	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.051256 (rank : 470)
Query Neighborhood Hits	156	Target Neighborhood Hits	864	Shared Neighborhood Hits	54
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BIN1_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.056697 (rank : 376)
Query Neighborhood Hits	156	Target Neighborhood Hits	283	Shared Neighborhood Hits	54
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BPAEA_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.057411 (rank : 363)
Query Neighborhood Hits	156	Target Neighborhood Hits	1480	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRE1A_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.063304 (rank : 259)
Query Neighborhood Hits	156	Target Neighborhood Hits	1071	Shared Neighborhood Hits	63
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.060499 (rank : 301)
Query Neighborhood Hits	156	Target Neighborhood Hits	1025	Shared Neighborhood Hits	63
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1B_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.054931 (rank : 414)
Query Neighborhood Hits	156	Target Neighborhood Hits	1040	Shared Neighborhood Hits	61
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.052161 (rank : 461)
Query Neighborhood Hits	156	Target Neighborhood Hits	970	Shared Neighborhood Hits	62
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

C102B_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.055620 (rank : 400)
Query Neighborhood Hits	156	Target Neighborhood Hits	542	Shared Neighborhood Hits	56
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CAF1A_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.050987 (rank : 476)
Query Neighborhood Hits	156	Target Neighborhood Hits	736	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CALD1_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.063708 (rank : 254)
Query Neighborhood Hits	156	Target Neighborhood Hits	959	Shared Neighborhood Hits	61
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CAR11_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.050034 (rank : 501)
Query Neighborhood Hits	156	Target Neighborhood Hits	690	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CARD9_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.053447 (rank : 438)
Query Neighborhood Hits	156	Target Neighborhood Hits	602	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CASL_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.061060 (rank : 291)
Query Neighborhood Hits	156	Target Neighborhood Hits	259	Shared Neighborhood Hits	59
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.058801 (rank : 341)
Query Neighborhood Hits	156	Target Neighborhood Hits	225	Shared Neighborhood Hits	52
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CCD11_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.057849 (rank : 353)
Query Neighborhood Hits	156	Target Neighborhood Hits	822	Shared Neighborhood Hits	65
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD11_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.059643 (rank : 329)
Query Neighborhood Hits	156	Target Neighborhood Hits	498	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD13_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.057797 (rank : 355)
Query Neighborhood Hits	156	Target Neighborhood Hits	721	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD19_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.067205 (rank : 212)
Query Neighborhood Hits	156	Target Neighborhood Hits	639	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.057417 (rank : 362)
Query Neighborhood Hits	156	Target Neighborhood Hits	1228	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.060204 (rank : 311)
Query Neighborhood Hits	156	Target Neighborhood Hits	1135	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD27_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.065665 (rank : 231)
Query Neighborhood Hits	156	Target Neighborhood Hits	594	Shared Neighborhood Hits	52
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD39_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.058016 (rank : 350)
Query Neighborhood Hits	156	Target Neighborhood Hits	868	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.059423 (rank : 333)
Query Neighborhood Hits	156	Target Neighborhood Hits	1026	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.058211 (rank : 349)
Query Neighborhood Hits	156	Target Neighborhood Hits	1139	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.057845 (rank : 354)
Query Neighborhood Hits	156	Target Neighborhood Hits	1399	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD42_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.051387 (rank : 468)
Query Neighborhood Hits	156	Target Neighborhood Hits	406	Shared Neighborhood Hits	47
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD62_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.051947 (rank : 462)
Query Neighborhood Hits	156	Target Neighborhood Hits	631	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD91_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.071020 (rank : 187)
Query Neighborhood Hits	156	Target Neighborhood Hits	868	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCD91_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.073324 (rank : 172)
Query Neighborhood Hits	156	Target Neighborhood Hits	699	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD96_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.060711 (rank : 298)
Query Neighborhood Hits	156	Target Neighborhood Hits	595	Shared Neighborhood Hits	55
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD96_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.062413 (rank : 268)
Query Neighborhood Hits	156	Target Neighborhood Hits	704	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.062464 (rank : 267)
Query Neighborhood Hits	156	Target Neighborhood Hits	723	Shared Neighborhood Hits	61
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.054632 (rank : 421)
Query Neighborhood Hits	156	Target Neighborhood Hits	717	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.059362 (rank : 334)
Query Neighborhood Hits	156	Target Neighborhood Hits	932	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CE152_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.060383 (rank : 305)
Query Neighborhood Hits	156	Target Neighborhood Hits	976	Shared Neighborhood Hits	62
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.068389 (rank : 204)
Query Neighborhood Hits	156	Target Neighborhood Hits	1553	Shared Neighborhood Hits	76
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPF_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.069323 (rank : 198)
Query Neighborhood Hits	156	Target Neighborhood Hits	1932	Shared Neighborhood Hits	78
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP55_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.056188 (rank : 386)
Query Neighborhood Hits	156	Target Neighborhood Hits	504	Shared Neighborhood Hits	50
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP55_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.063902 (rank : 250)
Query Neighborhood Hits	156	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP63_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.066135 (rank : 226)
Query Neighborhood Hits	156	Target Neighborhood Hits	1005	Shared Neighborhood Hits	63
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CEP70_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.054148 (rank : 431)
Query Neighborhood Hits	156	Target Neighborhood Hits	432	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CF060_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.065098 (rank : 236)
Query Neighborhood Hits	156	Target Neighborhood Hits	1270	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CF152_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.051763 (rank : 463)
Query Neighborhood Hits	156	Target Neighborhood Hits	704	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CF182_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.056801 (rank : 373)
Query Neighborhood Hits	156	Target Neighborhood Hits	551	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CI039_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.060651 (rank : 300)
Query Neighborhood Hits	156	Target Neighborhood Hits	1171	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.061848 (rank : 279)
Query Neighborhood Hits	156	Target Neighborhood Hits	1088	Shared Neighborhood Hits	65
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CING_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.060682 (rank : 299)
Query Neighborhood Hits	156	Target Neighborhood Hits	1275	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CJ118_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.055018 (rank : 410)
Query Neighborhood Hits	156	Target Neighborhood Hits	937	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CJ118_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.057908 (rank : 351)
Query Neighborhood Hits	156	Target Neighborhood Hits	1132	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CK5P2_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.057452 (rank : 361)
Query Neighborhood Hits	156	Target Neighborhood Hits	1433	Shared Neighborhood Hits	72
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.054955 (rank : 413)
Query Neighborhood Hits	156	Target Neighborhood Hits	1151	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CN145_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.066031 (rank : 228)
Query Neighborhood Hits	156	Target Neighborhood Hits	916	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CNTRB_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.055029 (rank : 408)
Query Neighborhood Hits	156	Target Neighborhood Hits	690	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CNTRB_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.065046 (rank : 238)
Query Neighborhood Hits	156	Target Neighborhood Hits	1029	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP135_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.060856 (rank : 293)
Query Neighborhood Hits	156	Target Neighborhood Hits	1290	Shared Neighborhood Hits	66
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP250_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.066840 (rank : 215)
Query Neighborhood Hits	156	Target Neighborhood Hits	1805	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP250_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.061590 (rank : 285)
Query Neighborhood Hits	156	Target Neighborhood Hits	1583	Shared Neighborhood Hits	77
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CR034_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.060714 (rank : 297)
Query Neighborhood Hits	156	Target Neighborhood Hits	538	Shared Neighborhood Hits	59
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CR034_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.053669 (rank : 436)
Query Neighborhood Hits	156	Target Neighborhood Hits	643	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CRKL_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.094854 (rank : 111)
Query Neighborhood Hits	156	Target Neighborhood Hits	313	Shared Neighborhood Hits	59
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.093125 (rank : 117)
Query Neighborhood Hits	156	Target Neighborhood Hits	307	Shared Neighborhood Hits	58
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.089853 (rank : 127)
Query Neighborhood Hits	156	Target Neighborhood Hits	308	Shared Neighborhood Hits	59
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.092380 (rank : 121)
Query Neighborhood Hits	156	Target Neighborhood Hits	314	Shared Neighborhood Hits	59
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CROCC_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.060078 (rank : 318)
Query Neighborhood Hits	156	Target Neighborhood Hits	1409	Shared Neighborhood Hits	75
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.056041 (rank : 390)
Query Neighborhood Hits	156	Target Neighborhood Hits	1460	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CT032_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.081139 (rank : 150)
Query Neighborhood Hits	156	Target Neighborhood Hits	235	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CT096_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.058785 (rank : 342)
Query Neighborhood Hits	156	Target Neighborhood Hits	438	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT2NL_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.057015 (rank : 369)
Query Neighborhood Hits	156	Target Neighborhood Hits	1059	Shared Neighborhood Hits	66
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.052281 (rank : 459)
Query Neighborhood Hits	156	Target Neighborhood Hits	902	Shared Neighborhood Hits	61
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CU013_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.053029 (rank : 444)
Query Neighborhood Hits	156	Target Neighborhood Hits	405	Shared Neighborhood Hits	46
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CUTL2_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.051141 (rank : 474)
Query Neighborhood Hits	156	Target Neighborhood Hits	906	Shared Neighborhood Hits	53
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CYLN2_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.054963 (rank : 412)
Query Neighborhood Hits	156	Target Neighborhood Hits	1004	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.058723 (rank : 343)
Query Neighborhood Hits	156	Target Neighborhood Hits	1002	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CYTSA_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.053031 (rank : 443)
Query Neighborhood Hits	156	Target Neighborhood Hits	1138	Shared Neighborhood Hits	68
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.050748 (rank : 483)
Query Neighborhood Hits	156	Target Neighborhood Hits	1104	Shared Neighborhood Hits	65
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DBNL_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.095926 (rank : 106)
Query Neighborhood Hits	156	Target Neighborhood Hits	244	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.095755 (rank : 108)
Query Neighborhood Hits	156	Target Neighborhood Hits	306	Shared Neighborhood Hits	62
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DESP_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.059088 (rank : 337)
Query Neighborhood Hits	156	Target Neighborhood Hits	1470	Shared Neighborhood Hits	74
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DLG5_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.050884 (rank : 481)
Query Neighborhood Hits	156	Target Neighborhood Hits	1088	Shared Neighborhood Hits	70
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DNMBP_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.157755 (rank : 45)
Query Neighborhood Hits	156	Target Neighborhood Hits	413	Shared Neighborhood Hits	75
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DYNA_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.059529 (rank : 331)
Query Neighborhood Hits	156	Target Neighborhood Hits	1194	Shared Neighborhood Hits	68
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.057884 (rank : 352)
Query Neighborhood Hits	156	Target Neighborhood Hits	1084	Shared Neighborhood Hits	67
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

ECT2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.087223 (rank : 139)
Query Neighborhood Hits	156	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.089649 (rank : 129)
Query Neighborhood Hits	156	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EEA1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.062466 (rank : 266)
Query Neighborhood Hits	156	Target Neighborhood Hits	1796	Shared Neighborhood Hits	81
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EEA1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.070931 (rank : 189)
Query Neighborhood Hits	156	Target Neighborhood Hits	1637	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EFS_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.066658 (rank : 218)
Query Neighborhood Hits	156	Target Neighborhood Hits	348	Shared Neighborhood Hits	55
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.071025 (rank : 186)
Query Neighborhood Hits	156	Target Neighborhood Hits	389	Shared Neighborhood Hits	58
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

EP15R_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.063416 (rank : 255)
Query Neighborhood Hits	156	Target Neighborhood Hits	1083	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.064409 (rank : 245)
Query Neighborhood Hits	156	Target Neighborhood Hits	1135	Shared Neighborhood Hits	58
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.071673 (rank : 181)
Query Neighborhood Hits	156	Target Neighborhood Hits	1021	Shared Neighborhood Hits	64
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.069605 (rank : 196)
Query Neighborhood Hits	156	Target Neighborhood Hits	820	Shared Neighborhood Hits	57
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ERC2_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.060050 (rank : 319)
Query Neighborhood Hits	156	Target Neighborhood Hits	1156	Shared Neighborhood Hits	71
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.064117 (rank : 248)
Query Neighborhood Hits	156	Target Neighborhood Hits	1166	Shared Neighborhood Hits	75
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

EVPL_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.059441 (rank : 332)
Query Neighborhood Hits	156	Target Neighborhood Hits	895	Shared Neighborhood Hits	60
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.057571 (rank : 360)
Query Neighborhood Hits	156	Target Neighborhood Hits	952	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FARP1_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.056296 (rank : 385)
Query Neighborhood Hits	156	Target Neighborhood Hits	241	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.055704 (rank : 397)
Query Neighborhood Hits	156	Target Neighborhood Hits	240	Shared Neighborhood Hits	22
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.060831 (rank : 294)
Query Neighborhood Hits	156	Target Neighborhood Hits	209	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FGD1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.067142 (rank : 214)
Query Neighborhood Hits	156	Target Neighborhood Hits	367	Shared Neighborhood Hits	32
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.065993 (rank : 229)
Query Neighborhood Hits	156	Target Neighborhood Hits	387	Shared Neighborhood Hits	30
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.074765 (rank : 170)
Query Neighborhood Hits	156	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.071316 (rank : 184)
Query Neighborhood Hits	156	Target Neighborhood Hits	163	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.071421 (rank : 183)
Query Neighborhood Hits	156	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.076442 (rank : 163)
Query Neighborhood Hits	156	Target Neighborhood Hits	257	Shared Neighborhood Hits	25
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.080819 (rank : 154)
Query Neighborhood Hits	156	Target Neighborhood Hits	219	Shared Neighborhood Hits	34
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.080601 (rank : 155)
Query Neighborhood Hits	156	Target Neighborhood Hits	227	Shared Neighborhood Hits	30
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD6_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.059079 (rank : 339)
Query Neighborhood Hits	156	Target Neighborhood Hits	237	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.064955 (rank : 240)
Query Neighborhood Hits	156	Target Neighborhood Hits	282	Shared Neighborhood Hits	33
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FLIP1_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.069784 (rank : 195)
Query Neighborhood Hits	156	Target Neighborhood Hits	1176	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FNBP2_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.058312 (rank : 348)
Query Neighborhood Hits	156	Target Neighborhood Hits	432	Shared Neighborhood Hits	75
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

FYCO1_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.055555 (rank : 401)
Query Neighborhood Hits	156	Target Neighborhood Hits	1149	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GAS8_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.061754 (rank : 281)
Query Neighborhood Hits	156	Target Neighborhood Hits	819	Shared Neighborhood Hits	61
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.060379 (rank : 306)
Query Neighborhood Hits	156	Target Neighborhood Hits	622	Shared Neighborhood Hits	54
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCC1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.057628 (rank : 358)
Query Neighborhood Hits	156	Target Neighborhood Hits	887	Shared Neighborhood Hits	58
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.060164 (rank : 314)
Query Neighborhood Hits	156	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC2_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.064400 (rank : 246)
Query Neighborhood Hits	156	Target Neighborhood Hits	1619	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GLE1_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.050838 (rank : 482)
Query Neighborhood Hits	156	Target Neighborhood Hits	504	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

GNRP_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.069590 (rank : 197)
Query Neighborhood Hits	156	Target Neighborhood Hits	239	Shared Neighborhood Hits	33
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.076440 (rank : 164)
Query Neighborhood Hits	156	Target Neighborhood Hits	191	Shared Neighborhood Hits	27
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GOG8A_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.052439 (rank : 457)
Query Neighborhood Hits	156	Target Neighborhood Hits	635	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA1_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.059766 (rank : 325)
Query Neighborhood Hits	156	Target Neighborhood Hits	1222	Shared Neighborhood Hits	66
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA1_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.062153 (rank : 273)
Query Neighborhood Hits	156	Target Neighborhood Hits	994	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.059931 (rank : 321)
Query Neighborhood Hits	156	Target Neighborhood Hits	856	Shared Neighborhood Hits	60
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA3_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.057638 (rank : 357)
Query Neighborhood Hits	156	Target Neighborhood Hits	1317	Shared Neighborhood Hits	65
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA4_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.063382 (rank : 256)
Query Neighborhood Hits	156	Target Neighborhood Hits	2034	Shared Neighborhood Hits	87
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA4_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.063019 (rank : 261)
Query Neighborhood Hits	156	Target Neighborhood Hits	1939	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.054391 (rank : 428)
Query Neighborhood Hits	156	Target Neighborhood Hits	1168	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.058617 (rank : 344)
Query Neighborhood Hits	156	Target Neighborhood Hits	1434	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.065067 (rank : 237)
Query Neighborhood Hits	156	Target Neighborhood Hits	1007	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GOGB1_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.065112 (rank : 235)
Query Neighborhood Hits	156	Target Neighborhood Hits	2297	Shared Neighborhood Hits	85
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRAP1_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.062896 (rank : 262)
Query Neighborhood Hits	156	Target Neighborhood Hits	944	Shared Neighborhood Hits	67
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GRAP1_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.060346 (rank : 307)
Query Neighborhood Hits	156	Target Neighborhood Hits	1234	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP2_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.093181 (rank : 116)
Query Neighborhood Hits	156	Target Neighborhood Hits	304	Shared Neighborhood Hits	57
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.095640 (rank : 110)
Query Neighborhood Hits	156	Target Neighborhood Hits	297	Shared Neighborhood Hits	58
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.099682 (rank : 101)
Query Neighborhood Hits	156	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.102550 (rank : 94)
Query Neighborhood Hits	156	Target Neighborhood Hits	309	Shared Neighborhood Hits	64
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.099510 (rank : 103)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	61
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.099527 (rank : 102)
Query Neighborhood Hits	156	Target Neighborhood Hits	312	Shared Neighborhood Hits	61
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HAPIP_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.079699 (rank : 156)
Query Neighborhood Hits	156	Target Neighborhood Hits	350	Shared Neighborhood Hits	47
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HCLS1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.110036 (rank : 80)
Query Neighborhood Hits	156	Target Neighborhood Hits	358	Shared Neighborhood Hits	61
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.111750 (rank : 76)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HIP1R_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.050609 (rank : 487)
Query Neighborhood Hits	156	Target Neighborhood Hits	809	Shared Neighborhood Hits	58
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.051617 (rank : 464)
Query Neighborhood Hits	156	Target Neighborhood Hits	959	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HMMR_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.062868 (rank : 263)
Query Neighborhood Hits	156	Target Neighborhood Hits	1082	Shared Neighborhood Hits	66
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.059965 (rank : 320)
Query Neighborhood Hits	156	Target Neighborhood Hits	1178	Shared Neighborhood Hits	73
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOOK1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.072907 (rank : 176)
Query Neighborhood Hits	156	Target Neighborhood Hits	942	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.066180 (rank : 223)
Query Neighborhood Hits	156	Target Neighborhood Hits	910	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.052602 (rank : 451)
Query Neighborhood Hits	156	Target Neighborhood Hits	736	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

HOOK3_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.056064 (rank : 389)
Query Neighborhood Hits	156	Target Neighborhood Hits	1070	Shared Neighborhood Hits	67
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.056086 (rank : 388)
Query Neighborhood Hits	156	Target Neighborhood Hits	1007	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

IASPP_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.057101 (rank : 367)
Query Neighborhood Hits	156	Target Neighborhood Hits	688	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.055119 (rank : 407)
Query Neighborhood Hits	156	Target Neighborhood Hits	1024	Shared Neighborhood Hits	65
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF2P_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.051462 (rank : 466)
Query Neighborhood Hits	156	Target Neighborhood Hits	889	Shared Neighborhood Hits	65
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF3A_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.068124 (rank : 205)
Query Neighborhood Hits	156	Target Neighborhood Hits	875	Shared Neighborhood Hits	74
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.067582 (rank : 208)
Query Neighborhood Hits	156	Target Neighborhood Hits	871	Shared Neighborhood Hits	71
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.061540 (rank : 286)
Query Neighborhood Hits	156	Target Neighborhood Hits	949	Shared Neighborhood Hits	57
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.060468 (rank : 303)
Query Neighborhood Hits	156	Target Neighborhood Hits	939	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.059873 (rank : 323)
Query Neighborhood Hits	156	Target Neighborhood Hits	893	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.059709 (rank : 327)
Query Neighborhood Hits	156	Target Neighborhood Hits	959	Shared Neighborhood Hits	60
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INCE_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.061941 (rank : 278)
Query Neighborhood Hits	156	Target Neighborhood Hits	978	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.066339 (rank : 221)
Query Neighborhood Hits	156	Target Neighborhood Hits	903	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INVO_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.062857 (rank : 264)
Query Neighborhood Hits	156	Target Neighborhood Hits	636	Shared Neighborhood Hits	57
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.050570 (rank : 489)
Query Neighborhood Hits	156	Target Neighborhood Hits	474	Shared Neighborhood Hits	50
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

K0555_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.061377 (rank : 287)
Query Neighborhood Hits	156	Target Neighborhood Hits	880	Shared Neighborhood Hits	63
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

KMHN1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.063985 (rank : 249)
Query Neighborhood Hits	156	Target Neighborhood Hits	950	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KMHN1_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.056997 (rank : 371)
Query Neighborhood Hits	156	Target Neighborhood Hits	949	Shared Neighborhood Hits	65
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

KNTC2_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.056768 (rank : 375)
Query Neighborhood Hits	156	Target Neighborhood Hits	673	Shared Neighborhood Hits	58
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KNTC2_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.054831 (rank : 416)
Query Neighborhood Hits	156	Target Neighborhood Hits	692	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KTN1_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.059005 (rank : 340)
Query Neighborhood Hits	156	Target Neighborhood Hits	1197	Shared Neighborhood Hits	65
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.059531 (rank : 330)
Query Neighborhood Hits	156	Target Neighborhood Hits	1324	Shared Neighborhood Hits	69
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LBC_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.070891 (rank : 190)
Query Neighborhood Hits	156	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LIPA1_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.050539 (rank : 491)
Query Neighborhood Hits	156	Target Neighborhood Hits	1294	Shared Neighborhood Hits	74
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LIPA2_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.050127 (rank : 499)
Query Neighborhood Hits	156	Target Neighborhood Hits	1282	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LRC45_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.064996 (rank : 239)
Query Neighborhood Hits	156	Target Neighborhood Hits	933	Shared Neighborhood Hits	64
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.061834 (rank : 280)
Query Neighborhood Hits	156	Target Neighborhood Hits	959	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF2_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.054585 (rank : 423)
Query Neighborhood Hits	156	Target Neighborhood Hits	791	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LUZP1_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.056476 (rank : 381)
Query Neighborhood Hits	156	Target Neighborhood Hits	739	Shared Neighborhood Hits	56
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LUZP1_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.059880 (rank : 322)
Query Neighborhood Hits	156	Target Neighborhood Hits	940	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

LZTS1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.050630 (rank : 485)
Query Neighborhood Hits	156	Target Neighborhood Hits	532	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MACOI_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.056689 (rank : 377)
Query Neighborhood Hits	156	Target Neighborhood Hits	650	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.055216 (rank : 405)
Query Neighborhood Hits	156	Target Neighborhood Hits	620	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MCF2L_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.092060 (rank : 123)
Query Neighborhood Hits	156	Target Neighborhood Hits	255	Shared Neighborhood Hits	41
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.088392 (rank : 135)
Query Neighborhood Hits	156	Target Neighborhood Hits	166	Shared Neighborhood Hits	32
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MD1L1_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.065288 (rank : 234)
Query Neighborhood Hits	156	Target Neighborhood Hits	893	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.061231 (rank : 289)
Query Neighborhood Hits	156	Target Neighborhood Hits	1001	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MFAP1_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.057241 (rank : 366)
Query Neighborhood Hits	156	Target Neighborhood Hits	321	Shared Neighborhood Hits	44
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MFAP1_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.067284 (rank : 211)
Query Neighborhood Hits	156	Target Neighborhood Hits	353	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

MIPO1_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.052816 (rank : 447)
Query Neighborhood Hits	156	Target Neighborhood Hits	486	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MY18A_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.057318 (rank : 364)
Query Neighborhood Hits	156	Target Neighborhood Hits	1929	Shared Neighborhood Hits	79
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.053523 (rank : 437)
Query Neighborhood Hits	156	Target Neighborhood Hits	1989	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18B_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.052389 (rank : 458)
Query Neighborhood Hits	156	Target Neighborhood Hits	1299	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH11_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.057000 (rank : 370)
Query Neighborhood Hits	156	Target Neighborhood Hits	1806	Shared Neighborhood Hits	89
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.052568 (rank : 453)
Query Neighborhood Hits	156	Target Neighborhood Hits	1777	Shared Neighborhood Hits	79
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH13_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.054122 (rank : 432)
Query Neighborhood Hits	156	Target Neighborhood Hits	1504	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.050624 (rank : 486)
Query Neighborhood Hits	156	Target Neighborhood Hits	1478	Shared Neighborhood Hits	76
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.050964 (rank : 477)
Query Neighborhood Hits	156	Target Neighborhood Hits	1461	Shared Neighborhood Hits	76
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.050711 (rank : 484)
Query Neighborhood Hits	156	Target Neighborhood Hits	1491	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH3_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.050449 (rank : 492)
Query Neighborhood Hits	156	Target Neighborhood Hits	1660	Shared Neighborhood Hits	79
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH4_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.050947 (rank : 478)
Query Neighborhood Hits	156	Target Neighborhood Hits	1476	Shared Neighborhood Hits	79
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.052518 (rank : 455)
Query Neighborhood Hits	156	Target Neighborhood Hits	1426	Shared Neighborhood Hits	70
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.053985 (rank : 433)
Query Neighborhood Hits	156	Target Neighborhood Hits	1559	Shared Neighborhood Hits	75
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH8_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.056808 (rank : 372)
Query Neighborhood Hits	156	Target Neighborhood Hits	1610	Shared Neighborhood Hits	79
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.051366 (rank : 469)
Query Neighborhood Hits	156	Target Neighborhood Hits	1600	Shared Neighborhood Hits	74
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH9_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.053927 (rank : 434)
Query Neighborhood Hits	156	Target Neighborhood Hits	1762	Shared Neighborhood Hits	84
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO1E_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.063154 (rank : 260)
Query Neighborhood Hits	156	Target Neighborhood Hits	293	Shared Neighborhood Hits	68
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.065472 (rank : 232)
Query Neighborhood Hits	156	Target Neighborhood Hits	275	Shared Neighborhood Hits	67
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.066146 (rank : 225)
Query Neighborhood Hits	156	Target Neighborhood Hits	262	Shared Neighborhood Hits	67
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NAF1_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.057613 (rank : 359)
Query Neighborhood Hits	156	Target Neighborhood Hits	937	Shared Neighborhood Hits	64
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.056341 (rank : 383)
Query Neighborhood Hits	156	Target Neighborhood Hits	852	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCF2_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.132464 (rank : 54)
Query Neighborhood Hits	156	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NEBU_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.104561 (rank : 91)
Query Neighborhood Hits	156	Target Neighborhood Hits	420	Shared Neighborhood Hits	72
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NEMO_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.054572 (rank : 424)
Query Neighborhood Hits	156	Target Neighborhood Hits	820	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NIN_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.059341 (rank : 335)
Query Neighborhood Hits	156	Target Neighborhood Hits	1376	Shared Neighborhood Hits	71
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NOXO1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.066753 (rank : 216)
Query Neighborhood Hits	156	Target Neighborhood Hits	100	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.079534 (rank : 157)
Query Neighborhood Hits	156	Target Neighborhood Hits	114	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.072104 (rank : 179)
Query Neighborhood Hits	156	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.077266 (rank : 162)
Query Neighborhood Hits	156	Target Neighborhood Hits	267	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NUF2_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.052869 (rank : 446)
Query Neighborhood Hits	156	Target Neighborhood Hits	661	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

NUF2_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.062102 (rank : 275)
Query Neighborhood Hits	156	Target Neighborhood Hits	585	Shared Neighborhood Hits	62
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

NUMA1_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.067291 (rank : 210)
Query Neighborhood Hits	156	Target Neighborhood Hits	1523	Shared Neighborhood Hits	81
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

OFD1_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.060914 (rank : 292)
Query Neighborhood Hits	156	Target Neighborhood Hits	753	Shared Neighborhood Hits	60
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

OPTN_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.060793 (rank : 295)
Query Neighborhood Hits	156	Target Neighborhood Hits	827	Shared Neighborhood Hits	59
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.054245 (rank : 430)
Query Neighborhood Hits	156	Target Neighborhood Hits	1120	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

OSTF1_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.090947 (rank : 125)
Query Neighborhood Hits	156	Target Neighborhood Hits	466	Shared Neighborhood Hits	67
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.089235 (rank : 130)
Query Neighborhood Hits	156	Target Neighborhood Hits	467	Shared Neighborhood Hits	67
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

P85A_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.066455 (rank : 220)
Query Neighborhood Hits	156	Target Neighborhood Hits	479	Shared Neighborhood Hits	66
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.063746 (rank : 252)
Query Neighborhood Hits	156	Target Neighborhood Hits	435	Shared Neighborhood Hits	60
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.061726 (rank : 283)
Query Neighborhood Hits	156	Target Neighborhood Hits	543	Shared Neighborhood Hits	69
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.060260 (rank : 310)
Query Neighborhood Hits	156	Target Neighborhood Hits	519	Shared Neighborhood Hits	70
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCNT_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.062525 (rank : 265)
Query Neighborhood Hits	156	Target Neighborhood Hits	1551	Shared Neighborhood Hits	81
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PCNT_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.058412 (rank : 347)
Query Neighborhood Hits	156	Target Neighborhood Hits	1207	Shared Neighborhood Hits	68
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PEPL_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.067375 (rank : 209)
Query Neighborhood Hits	156	Target Neighborhood Hits	1141	Shared Neighborhood Hits	65
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.062397 (rank : 269)
Query Neighborhood Hits	156	Target Neighborhood Hits	1105	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PEX13_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.087300 (rank : 138)
Query Neighborhood Hits	156	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.088842 (rank : 133)
Query Neighborhood Hits	156	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PIBF1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.062263 (rank : 271)
Query Neighborhood Hits	156	Target Neighborhood Hits	1041	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PININ_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.056118 (rank : 387)
Query Neighborhood Hits	156	Target Neighborhood Hits	753	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.052215 (rank : 460)
Query Neighborhood Hits	156	Target Neighborhood Hits	777	Shared Neighborhood Hits	54
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PKHG1_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.116157 (rank : 68)
Query Neighborhood Hits	156	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PLCG1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.073168 (rank : 175)
Query Neighborhood Hits	156	Target Neighborhood Hits	293	Shared Neighborhood Hits	47
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.075345 (rank : 168)
Query Neighborhood Hits	156	Target Neighborhood Hits	314	Shared Neighborhood Hits	49
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.068878 (rank : 201)
Query Neighborhood Hits	156	Target Neighborhood Hits	280	Shared Neighborhood Hits	45
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PLEC1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.056319 (rank : 384)
Query Neighborhood Hits	156	Target Neighborhood Hits	1326	Shared Neighborhood Hits	69
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PPIP1_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.124632 (rank : 62)
Query Neighborhood Hits	156	Target Neighborhood Hits	389	Shared Neighborhood Hits	89
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PPIP1_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.122204 (rank : 65)
Query Neighborhood Hits	156	Target Neighborhood Hits	377	Shared Neighborhood Hits	84
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PPIP2_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.056633 (rank : 379)
Query Neighborhood Hits	156	Target Neighborhood Hits	254	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

PPIP2_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.054689 (rank : 419)
Query Neighborhood Hits	156	Target Neighborhood Hits	308	Shared Neighborhood Hits	51
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PRC1_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.050568 (rank : 490)
Query Neighborhood Hits	156	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PREX1_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.111439 (rank : 77)
Query Neighborhood Hits	156	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RABE2_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.050226 (rank : 498)
Query Neighborhood Hits	156	Target Neighborhood Hits	545	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RABE2_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.052527 (rank : 454)
Query Neighborhood Hits	156	Target Neighborhood Hits	598	Shared Neighborhood Hits	51
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAD50_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.075002 (rank : 169)
Query Neighborhood Hits	156	Target Neighborhood Hits	1317	Shared Neighborhood Hits	71
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.073308 (rank : 173)
Query Neighborhood Hits	156	Target Neighborhood Hits	1366	Shared Neighborhood Hits	73
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RASF8_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.054348 (rank : 429)
Query Neighborhood Hits	156	Target Neighborhood Hits	469	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

RB6I2_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.062318 (rank : 270)
Query Neighborhood Hits	156	Target Neighborhood Hits	1584	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.062168 (rank : 272)
Query Neighborhood Hits	156	Target Neighborhood Hits	1433	Shared Neighborhood Hits	70
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBCC1_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.061201 (rank : 290)
Query Neighborhood Hits	156	Target Neighborhood Hits	1023	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBCC1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.059232 (rank : 336)
Query Neighborhood Hits	156	Target Neighborhood Hits	1048	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

REN3B_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.050349 (rank : 497)
Query Neighborhood Hits	156	Target Neighborhood Hits	412	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RENT2_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.050097 (rank : 500)
Query Neighborhood Hits	156	Target Neighborhood Hits	618	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

REST_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.059725 (rank : 326)
Query Neighborhood Hits	156	Target Neighborhood Hits	1605	Shared Neighborhood Hits	71
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.055490 (rank : 403)
Query Neighborhood Hits	156	Target Neighborhood Hits	1506	Shared Neighborhood Hits	66
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFIP3_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.052941 (rank : 445)
Query Neighborhood Hits	156	Target Neighborhood Hits	1055	Shared Neighborhood Hits	61
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP4_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.053181 (rank : 441)
Query Neighborhood Hits	156	Target Neighborhood Hits	785	Shared Neighborhood Hits	56
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RGNEF_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.085992 (rank : 144)
Query Neighborhood Hits	156	Target Neighborhood Hits	641	Shared Neighborhood Hits	60
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RHG04_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.060173 (rank : 312)
Query Neighborhood Hits	156	Target Neighborhood Hits	307	Shared Neighborhood Hits	56
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RIMB2_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.086926 (rank : 140)
Query Neighborhood Hits	156	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RPGR1_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.053772 (rank : 435)
Query Neighborhood Hits	156	Target Neighborhood Hits	578	Shared Neighborhood Hits	50
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RRBP1_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.052654 (rank : 449)
Query Neighborhood Hits	156	Target Neighborhood Hits	1306	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RUFY1_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.055658 (rank : 399)
Query Neighborhood Hits	156	Target Neighborhood Hits	848	Shared Neighborhood Hits	60
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.055963 (rank : 391)
Query Neighborhood Hits	156	Target Neighborhood Hits	765	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.050579 (rank : 488)
Query Neighborhood Hits	156	Target Neighborhood Hits	820	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUSC1_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.050388 (rank : 494)
Query Neighborhood Hits	156	Target Neighborhood Hits	226	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SAS6_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.063328 (rank : 258)
Query Neighborhood Hits	156	Target Neighborhood Hits	791	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SDCG8_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.060341 (rank : 308)
Query Neighborhood Hits	156	Target Neighborhood Hits	1002	Shared Neighborhood Hits	61
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.055028 (rank : 409)
Query Neighborhood Hits	156	Target Neighborhood Hits	886	Shared Neighborhood Hits	60
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SH3G1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.118322 (rank : 67)
Query Neighborhood Hits	156	Target Neighborhood Hits	307	Shared Neighborhood Hits	76
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.125122 (rank : 61)
Query Neighborhood Hits	156	Target Neighborhood Hits	291	Shared Neighborhood Hits	72
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G3_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.121584 (rank : 66)
Query Neighborhood Hits	156	Target Neighborhood Hits	222	Shared Neighborhood Hits	63
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G3_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.141659 (rank : 52)
Query Neighborhood Hits	156	Target Neighborhood Hits	236	Shared Neighborhood Hits	67
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SMC3_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.083502 (rank : 147)
Query Neighborhood Hits	156	Target Neighborhood Hits	1186	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.083414 (rank : 148)
Query Neighborhood Hits	156	Target Neighborhood Hits	1187	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC4_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.070980 (rank : 188)
Query Neighborhood Hits	156	Target Neighborhood Hits	937	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SMC4_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.071207 (rank : 185)
Query Neighborhood Hits	156	Target Neighborhood Hits	830	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SMCE1_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.060119 (rank : 315)
Query Neighborhood Hits	156	Target Neighborhood Hits	272	Shared Neighborhood Hits	26
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.064880 (rank : 241)
Query Neighborhood Hits	156	Target Neighborhood Hits	409	Shared Neighborhood Hits	30
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SNX18_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.091691 (rank : 124)
Query Neighborhood Hits	156	Target Neighborhood Hits	207	Shared Neighborhood Hits	50
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.093025 (rank : 118)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SPAG5_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.053421 (rank : 439)
Query Neighborhood Hits	156	Target Neighborhood Hits	612	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SPN90_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.052621 (rank : 450)
Query Neighborhood Hits	156	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPTA1_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.067591 (rank : 207)
Query Neighborhood Hits	156	Target Neighborhood Hits	748	Shared Neighborhood Hits	98
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.063347 (rank : 257)
Query Neighborhood Hits	156	Target Neighborhood Hits	675	Shared Neighborhood Hits	91
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SRBS1_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.164407 (rank : 39)
Query Neighborhood Hits	156	Target Neighborhood Hits	409	Shared Neighborhood Hits	72
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.109169 (rank : 82)
Query Neighborhood Hits	156	Target Neighborhood Hits	269	Shared Neighborhood Hits	61
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.108638 (rank : 84)
Query Neighborhood Hits	156	Target Neighborhood Hits	292	Shared Neighborhood Hits	62
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRGP1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.055814 (rank : 395)
Query Neighborhood Hits	156	Target Neighborhood Hits	390	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.065351 (rank : 233)
Query Neighborhood Hits	156	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.066181 (rank : 222)
Query Neighborhood Hits	156	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

STAC3_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.100239 (rank : 98)
Query Neighborhood Hits	156	Target Neighborhood Hits	228	Shared Neighborhood Hits	57
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.101319 (rank : 97)
Query Neighborhood Hits	156	Target Neighborhood Hits	232	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAM1_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.107843 (rank : 85)
Query Neighborhood Hits	156	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.107783 (rank : 86)
Query Neighborhood Hits	156	Target Neighborhood Hits	273	Shared Neighborhood Hits	62
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.103020 (rank : 93)
Query Neighborhood Hits	156	Target Neighborhood Hits	288	Shared Neighborhood Hits	68
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.109148 (rank : 83)
Query Neighborhood Hits	156	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STS1_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.052590 (rank : 452)
Query Neighborhood Hits	156	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS2_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.071672 (rank : 182)
Query Neighborhood Hits	156	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SWP70_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.069228 (rank : 200)
Query Neighborhood Hits	156	Target Neighborhood Hits	973	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.060114 (rank : 316)
Query Neighborhood Hits	156	Target Neighborhood Hits	1097	Shared Neighborhood Hits	68
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYCP1_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.069885 (rank : 194)
Query Neighborhood Hits	156	Target Neighborhood Hits	1456	Shared Neighborhood Hits	75
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYNE1_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.050356 (rank : 496)
Query Neighborhood Hits	156	Target Neighborhood Hits	1484	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TACC1_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.051164 (rank : 473)
Query Neighborhood Hits	156	Target Neighborhood Hits	667	Shared Neighborhood Hits	56
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TACC3_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.054397 (rank : 427)
Query Neighborhood Hits	156	Target Neighborhood Hits	607	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TAXB1_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.060169 (rank : 313)
Query Neighborhood Hits	156	Target Neighborhood Hits	829	Shared Neighborhood Hits	61
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TAXB1_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.055322 (rank : 404)
Query Neighborhood Hits	156	Target Neighborhood Hits	886	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TCRG1_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.055868 (rank : 393)
Query Neighborhood Hits	156	Target Neighborhood Hits	929	Shared Neighborhood Hits	55
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.055551 (rank : 402)
Query Neighborhood Hits	156	Target Neighborhood Hits	947	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEX9_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.056374 (rank : 382)
Query Neighborhood Hits	156	Target Neighborhood Hits	541	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TEX9_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.065697 (rank : 230)
Query Neighborhood Hits	156	Target Neighborhood Hits	581	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TIAM1_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.107305 (rank : 87)
Query Neighborhood Hits	156	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.109432 (rank : 81)
Query Neighborhood Hits	156	Target Neighborhood Hits	205	Shared Neighborhood Hits	26
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TMF1_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.071981 (rank : 180)
Query Neighborhood Hits	156	Target Neighborhood Hits	987	Shared Neighborhood Hits	68
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TNIP3_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.061740 (rank : 282)
Query Neighborhood Hits	156	Target Neighborhood Hits	511	Shared Neighborhood Hits	53
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TPM1_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.055814 (rank : 394)
Query Neighborhood Hits	156	Target Neighborhood Hits	716	Shared Neighborhood Hits	60
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.055694 (rank : 398)
Query Neighborhood Hits	156	Target Neighborhood Hits	729	Shared Neighborhood Hits	61
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM2_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.055777 (rank : 396)
Query Neighborhood Hits	156	Target Neighborhood Hits	677	Shared Neighborhood Hits	59
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.055186 (rank : 406)
Query Neighborhood Hits	156	Target Neighborhood Hits	676	Shared Neighborhood Hits	59
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM3_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.057041 (rank : 368)
Query Neighborhood Hits	156	Target Neighborhood Hits	689	Shared Neighborhood Hits	61
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TPM3_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.056634 (rank : 378)
Query Neighborhood Hits	156	Target Neighborhood Hits	676	Shared Neighborhood Hits	62
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

TPM4_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.050373 (rank : 495)
Query Neighborhood Hits	156	Target Neighborhood Hits	525	Shared Neighborhood Hits	52
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

TPM4_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.053242 (rank : 440)
Query Neighborhood Hits	156	Target Neighborhood Hits	703	Shared Neighborhood Hits	58
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TRAIP_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.051059 (rank : 475)
Query Neighborhood Hits	156	Target Neighborhood Hits	780	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.051612 (rank : 465)
Query Neighborhood Hits	156	Target Neighborhood Hits	745	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRHY_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.063712 (rank : 253)
Query Neighborhood Hits	156	Target Neighborhood Hits	1385	Shared Neighborhood Hits	71
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRIPB_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.060748 (rank : 296)
Query Neighborhood Hits	156	Target Neighborhood Hits	1587	Shared Neighborhood Hits	74
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TSC1_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.059085 (rank : 338)
Query Neighborhood Hits	156	Target Neighborhood Hits	765	Shared Neighborhood Hits	54
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TTC3_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.070050 (rank : 193)
Query Neighborhood Hits	156	Target Neighborhood Hits	664	Shared Neighborhood Hits	58
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TUFT1_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.054445 (rank : 426)
Query Neighborhood Hits	156	Target Neighborhood Hits	686	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.051186 (rank : 472)
Query Neighborhood Hits	156	Target Neighborhood Hits	732	Shared Neighborhood Hits	52
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

UACA_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.059778 (rank : 324)
Query Neighborhood Hits	156	Target Neighborhood Hits	1620	Shared Neighborhood Hits	78
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

VINEX_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.150551 (rank : 49)
Query Neighborhood Hits	156	Target Neighborhood Hits	270	Shared Neighborhood Hits	69
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.160979 (rank : 41)
Query Neighborhood Hits	156	Target Neighborhood Hits	286	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ZN291_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.057263 (rank : 365)
Query Neighborhood Hits	156	Target Neighborhood Hits	647	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

Hits sorted by NC score

BI2L1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	156	Target Neighborhood Hits	156	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BI2L1_MOUSE
NC score	0.960716 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	156	Target Neighborhood Hits	197	Shared Neighborhood Hits	97
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BAIP2_MOUSE
NC score	0.900856 (rank : 3)	θ value	4.33309e-103 (rank : 4)
Query Neighborhood Hits	156	Target Neighborhood Hits	185	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BAIP2_HUMAN
NC score	0.897188 (rank : 4)	θ value	9.96626e-108 (rank : 3)
Query Neighborhood Hits	156	Target Neighborhood Hits	192	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

MTSS1_HUMAN
NC score	0.312620 (rank : 5)	θ value	1.99992e-07 (rank : 5)
Query Neighborhood Hits	156	Target Neighborhood Hits	504	Shared Neighborhood Hits	24
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
NC score	0.279567 (rank : 6)	θ value	1.43324e-05 (rank : 7)
Query Neighborhood Hits	156	Target Neighborhood Hits	592	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NCF4_MOUSE
NC score	0.234425 (rank : 7)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	156	Target Neighborhood Hits	177	Shared Neighborhood Hits	56
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ITSN2_MOUSE
NC score	0.227023 (rank : 8)	θ value	1.87187e-05 (rank : 8)
Query Neighborhood Hits	156	Target Neighborhood Hits	1371	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITSN1_MOUSE
NC score	0.225678 (rank : 9)	θ value	3.77169e-06 (rank : 6)
Query Neighborhood Hits	156	Target Neighborhood Hits	1669	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
NC score	0.222885 (rank : 10)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	156	Target Neighborhood Hits	1173	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN1_HUMAN
NC score	0.220196 (rank : 11)	θ value	0.000270298 (rank : 10)
Query Neighborhood Hits	156	Target Neighborhood Hits	1757	Shared Neighborhood Hits	135
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SH3K1_HUMAN
NC score	0.219644 (rank : 12)	θ value	0.0330416 (rank : 27)
Query Neighborhood Hits	156	Target Neighborhood Hits	341	Shared Neighborhood Hits	70
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
NC score	0.217428 (rank : 13)	θ value	0.0330416 (rank : 28)
Query Neighborhood Hits	156	Target Neighborhood Hits	332	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

NCF4_HUMAN
NC score	0.210443 (rank : 14)	θ value	0.0431538 (rank : 31)
Query Neighborhood Hits	156	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ARHG6_HUMAN
NC score	0.207713 (rank : 15)	θ value	0.00869519 (rank : 11)
Query Neighborhood Hits	156	Target Neighborhood Hits	376	Shared Neighborhood Hits	82
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
NC score	0.202387 (rank : 16)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	156	Target Neighborhood Hits	394	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_MOUSE
NC score	0.201614 (rank : 17)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	156	Target Neighborhood Hits	396	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHGG_HUMAN
NC score	0.196429 (rank : 18)	θ value	0.0330416 (rank : 26)
Query Neighborhood Hits	156	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

PACN3_MOUSE
NC score	0.195888 (rank : 19)	θ value	0.0113563 (rank : 19)
Query Neighborhood Hits	156	Target Neighborhood Hits	380	Shared Neighborhood Hits	84
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

NGEF_MOUSE
NC score	0.195039 (rank : 20)	θ value	0.00869519 (rank : 14)
Query Neighborhood Hits	156	Target Neighborhood Hits	228	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PACN1_HUMAN
NC score	0.195013 (rank : 21)	θ value	0.0431538 (rank : 32)
Query Neighborhood Hits	156	Target Neighborhood Hits	320	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

ARHGG_MOUSE
NC score	0.194521 (rank : 22)	θ value	0.0563607 (rank : 34)
Query Neighborhood Hits	156	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHG9_MOUSE
NC score	0.192952 (rank : 23)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	156	Target Neighborhood Hits	234	Shared Neighborhood Hits	60
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG7_HUMAN
NC score	0.192582 (rank : 24)	θ value	0.0193708 (rank : 22)
Query Neighborhood Hits	156	Target Neighborhood Hits	347	Shared Neighborhood Hits	71
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG9_HUMAN
NC score	0.192538 (rank : 25)	θ value	0.00869519 (rank : 13)
Query Neighborhood Hits	156	Target Neighborhood Hits	235	Shared Neighborhood Hits	61
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

PACN3_HUMAN
NC score	0.190861 (rank : 26)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	156	Target Neighborhood Hits	385	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

CD2AP_MOUSE
NC score	0.190148 (rank : 27)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	156	Target Neighborhood Hits	336	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

PACN2_HUMAN
NC score	0.188935 (rank : 28)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	156	Target Neighborhood Hits	339	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

NGEF_HUMAN
NC score	0.187984 (rank : 29)	θ value	0.0148317 (rank : 21)
Query Neighborhood Hits	156	Target Neighborhood Hits	166	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PACN2_MOUSE
NC score	0.185536 (rank : 30)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	156	Target Neighborhood Hits	382	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

LASP1_HUMAN
NC score	0.185479 (rank : 31)	θ value	0.0252991 (rank : 24)
Query Neighborhood Hits	156	Target Neighborhood Hits	293	Shared Neighborhood Hits	61
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

DNMBP_MOUSE
NC score	0.185217 (rank : 32)	θ value	0.0113563 (rank : 16)
Query Neighborhood Hits	156	Target Neighborhood Hits	435	Shared Neighborhood Hits	77
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

LASP1_MOUSE
NC score	0.185132 (rank : 33)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	156	Target Neighborhood Hits	297	Shared Neighborhood Hits	61
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

NCF1_MOUSE
NC score	0.183218 (rank : 34)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	58
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

CD2AP_HUMAN
NC score	0.180938 (rank : 35)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	156	Target Neighborhood Hits	315	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

PACN1_MOUSE
NC score	0.180475 (rank : 36)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	156	Target Neighborhood Hits	283	Shared Neighborhood Hits	76
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

SRBS1_HUMAN
NC score	0.167556 (rank : 37)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	156	Target Neighborhood Hits	396	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ARHG4_HUMAN
NC score	0.165683 (rank : 38)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	156	Target Neighborhood Hits	242	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

SRBS1_MOUSE
NC score	0.164407 (rank : 39)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	156	Target Neighborhood Hits	409	Shared Neighborhood Hits	72
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

VAV_MOUSE
NC score	0.161363 (rank : 40)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	156	Target Neighborhood Hits	430	Shared Neighborhood Hits	68
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VINEX_MOUSE
NC score	0.160979 (rank : 41)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	156	Target Neighborhood Hits	286	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SNX9_HUMAN
NC score	0.160205 (rank : 42)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	156	Target Neighborhood Hits	148	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

VAV_HUMAN
NC score	0.159483 (rank : 43)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	156	Target Neighborhood Hits	452	Shared Neighborhood Hits	71
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

NCF1_HUMAN
NC score	0.159458 (rank : 44)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	55
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

DNMBP_HUMAN
NC score	0.157755 (rank : 45)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	156	Target Neighborhood Hits	413	Shared Neighborhood Hits	75
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

VAV2_HUMAN
NC score	0.156107 (rank : 46)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	156	Target Neighborhood Hits	453	Shared Neighborhood Hits	68
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ARHG4_MOUSE
NC score	0.153992 (rank : 47)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	156	Target Neighborhood Hits	185	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

VAV2_MOUSE
NC score	0.153682 (rank : 48)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	156	Target Neighborhood Hits	456	Shared Neighborhood Hits	68
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VINEX_HUMAN
NC score	0.150551 (rank : 49)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	156	Target Neighborhood Hits	270	Shared Neighborhood Hits	69
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

NEBL_HUMAN
NC score	0.148477 (rank : 50)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	156	Target Neighborhood Hits	457	Shared Neighborhood Hits	90
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

ARHG5_HUMAN
NC score	0.147814 (rank : 51)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	156	Target Neighborhood Hits	172	Shared Neighborhood Hits	49
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

SH3G3_MOUSE
NC score	0.141659 (rank : 52)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	156	Target Neighborhood Hits	236	Shared Neighborhood Hits	67
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SNX9_MOUSE
NC score	0.139902 (rank : 53)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	156	Target Neighborhood Hits	141	Shared Neighborhood Hits	43
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

NCF2_HUMAN
NC score	0.132464 (rank : 54)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	156	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

DDEF1_MOUSE
NC score	0.129217 (rank : 55)	θ value	0.0113563 (rank : 15)
Query Neighborhood Hits	156	Target Neighborhood Hits	592	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

NCK1_HUMAN
NC score	0.128943 (rank : 56)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	156	Target Neighborhood Hits	312	Shared Neighborhood Hits	68
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

VAV3_HUMAN
NC score	0.128449 (rank : 57)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	156	Target Neighborhood Hits	398	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

STAC_HUMAN
NC score	0.128025 (rank : 58)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	156	Target Neighborhood Hits	276	Shared Neighborhood Hits	60
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VAV3_MOUSE
NC score	0.125749 (rank : 59)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	156	Target Neighborhood Hits	404	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

SH3G2_MOUSE
NC score	0.125279 (rank : 60)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	156	Target Neighborhood Hits	319	Shared Neighborhood Hits	75
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G1_MOUSE
NC score	0.125122 (rank : 61)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	156	Target Neighborhood Hits	291	Shared Neighborhood Hits	72
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

PPIP1_HUMAN
NC score	0.124632 (rank : 62)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	156	Target Neighborhood Hits	389	Shared Neighborhood Hits	89
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SH3G2_HUMAN
NC score	0.123349 (rank : 63)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	156	Target Neighborhood Hits	324	Shared Neighborhood Hits	71
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

NCK2_HUMAN
NC score	0.122385 (rank : 64)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

PPIP1_MOUSE
NC score	0.122204 (rank : 65)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	156	Target Neighborhood Hits	377	Shared Neighborhood Hits	84
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SH3G3_HUMAN
NC score	0.121584 (rank : 66)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	156	Target Neighborhood Hits	222	Shared Neighborhood Hits	63
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G1_HUMAN
NC score	0.118322 (rank : 67)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	156	Target Neighborhood Hits	307	Shared Neighborhood Hits	76
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

PKHG1_HUMAN
NC score	0.116157 (rank : 68)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	156	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ABI2_MOUSE
NC score	0.115121 (rank : 69)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	156	Target Neighborhood Hits	266	Shared Neighborhood Hits	60
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI2_HUMAN
NC score	0.114541 (rank : 70)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	156	Target Neighborhood Hits	350	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

SMC2_MOUSE
NC score	0.114228 (rank : 71)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	156	Target Neighborhood Hits	1131	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

STAC_MOUSE
NC score	0.114154 (rank : 72)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	156	Target Neighborhood Hits	268	Shared Neighborhood Hits	58
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ARHG8_MOUSE
NC score	0.113531 (rank : 73)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	156	Target Neighborhood Hits	79	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGF_HUMAN
NC score	0.112530 (rank : 74)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	156	Target Neighborhood Hits	214	Shared Neighborhood Hits	23
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHG3_HUMAN
NC score	0.111773 (rank : 75)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	156	Target Neighborhood Hits	82	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

HCLS1_MOUSE
NC score	0.111750 (rank : 76)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	156	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

PREX1_HUMAN
NC score	0.111439 (rank : 77)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	156	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

ARHG3_MOUSE
NC score	0.111310 (rank : 78)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	156	Target Neighborhood Hits	85	Shared Neighborhood Hits	24
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ABI1_MOUSE
NC score	0.110813 (rank : 79)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	156	Target Neighborhood Hits	246	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

HCLS1_HUMAN
NC score	0.110036 (rank : 80)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	156	Target Neighborhood Hits	358	Shared Neighborhood Hits	61
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

TIAM1_MOUSE
NC score	0.109432 (rank : 81)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	156	Target Neighborhood Hits	205	Shared Neighborhood Hits	26
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SRC8_HUMAN
NC score	0.109169 (rank : 82)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	156	Target Neighborhood Hits	269	Shared Neighborhood Hits	61
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

STAM2_MOUSE
NC score	0.109148 (rank : 83)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	156	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SRC8_MOUSE
NC score	0.108638 (rank : 84)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	156	Target Neighborhood Hits	292	Shared Neighborhood Hits	62
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

STAM1_HUMAN
NC score	0.107843 (rank : 85)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	156	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
NC score	0.107783 (rank : 86)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	156	Target Neighborhood Hits	273	Shared Neighborhood Hits	62
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TIAM1_HUMAN
NC score	0.107305 (rank : 87)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	156	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

DDEF2_MOUSE
NC score	0.107072 (rank : 88)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	156	Target Neighborhood Hits	625	Shared Neighborhood Hits	69
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ABI1_HUMAN
NC score	0.105839 (rank : 89)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	156	Target Neighborhood Hits	257	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ARHG8_HUMAN
NC score	0.105585 (rank : 90)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	156	Target Neighborhood Hits	85	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

NEBU_HUMAN
NC score	0.104561 (rank : 91)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	156	Target Neighborhood Hits	420	Shared Neighborhood Hits	72
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

SMC1A_HUMAN
NC score	0.104010 (rank : 92)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	156	Target Neighborhood Hits	1346	Shared Neighborhood Hits	82
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

STAM2_HUMAN
NC score	0.103020 (rank : 93)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	156	Target Neighborhood Hits	288	Shared Neighborhood Hits	68
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

GRAP_MOUSE
NC score	0.102550 (rank : 94)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	156	Target Neighborhood Hits	309	Shared Neighborhood Hits	64
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SMC1A_MOUSE
NC score	0.102157 (rank : 95)	θ value	0.0736092 (rank : 36)
Query Neighborhood Hits	156	Target Neighborhood Hits	1384	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_HUMAN
NC score	0.101614 (rank : 96)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	156	Target Neighborhood Hits	1405	Shared Neighborhood Hits	75
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

STAC3_MOUSE
NC score	0.101319 (rank : 97)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	156	Target Neighborhood Hits	232	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_HUMAN
NC score	0.100239 (rank : 98)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	156	Target Neighborhood Hits	228	Shared Neighborhood Hits	57
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

ABI3_HUMAN
NC score	0.099953 (rank : 99)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	156	Target Neighborhood Hits	227	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

DDEF2_HUMAN
NC score	0.099915 (rank : 100)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	156	Target Neighborhood Hits	599	Shared Neighborhood Hits	77
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

GRAP_HUMAN
NC score	0.099682 (rank : 101)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	156	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRB2_MOUSE
NC score	0.099527 (rank : 102)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	156	Target Neighborhood Hits	312	Shared Neighborhood Hits	61
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRB2_HUMAN
NC score	0.099510 (rank : 103)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	156	Target Neighborhood Hits	310	Shared Neighborhood Hits	61
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

MAP9_MOUSE
NC score	0.098765 (rank : 104)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	156	Target Neighborhood Hits	529	Shared Neighborhood Hits	48
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

CIP4_HUMAN
NC score	0.097253 (rank : 105)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	156	Target Neighborhood Hits	374	Shared Neighborhood Hits	52
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DBNL_HUMAN
NC score	0.095926 (rank : 106)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	156	Target Neighborhood Hits	244	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

RHG26_HUMAN
NC score	0.095860 (rank : 107)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	156	Target Neighborhood Hits	281	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

DBNL_MOUSE
NC score	0.095755 (rank : 108)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	156	Target Neighborhood Hits	306	Shared Neighborhood Hits	62
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

RIMB2_HUMAN
NC score	0.095666 (rank : 109)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	156	Target Neighborhood Hits	263	Shared Neighborhood Hits	48
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

GRAP2_MOUSE
NC score	0.095640 (rank : 110)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	156	Target Neighborhood Hits	297	Shared Neighborhood Hits	58
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

CRKL_HUMAN
NC score	0.094854 (rank : 111)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	156	Target Neighborhood Hits	313	Shared Neighborhood Hits	59
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

TACC2_MOUSE
NC score	0.094019 (rank : 112)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	156	Target Neighborhood Hits	774	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

RIMB1_HUMAN
NC score	0.093938 (rank : 113)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	156	Target Neighborhood Hits	1479	Shared Neighborhood Hits	102
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CASP_HUMAN
NC score	0.093928 (rank : 114)	θ value	0.0961366 (rank : 37)
Query Neighborhood Hits	156	Target Neighborhood Hits	1131	Shared Neighborhood Hits	68
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

MAP9_HUMAN
NC score	0.093309 (rank : 115)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	156	Target Neighborhood Hits	518	Shared Neighborhood Hits	50
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

GRAP2_HUMAN
NC score	0.093181 (rank : 116)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	156	Target Neighborhood Hits	304	Shared Neighborhood Hits	57
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

CRKL_MOUSE
NC score	0.093125 (rank : 117)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	156	Target Neighborhood Hits	307	Shared Neighborhood Hits	58
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

SNX18_MOUSE
NC score	0.093025 (rank : 118)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

ABI3_MOUSE
NC score	0.092912 (rank : 119)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	156	Target Neighborhood Hits	227	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CASP_MOUSE
NC score	0.092477 (rank : 120)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	156	Target Neighborhood Hits	1152	Shared Neighborhood Hits	68
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CRK_MOUSE
NC score	0.092380 (rank : 121)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	156	Target Neighborhood Hits	314	Shared Neighborhood Hits	59
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CN145_HUMAN
NC score	0.092173 (rank : 122)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	156	Target Neighborhood Hits	1196	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MCF2L_MOUSE
NC score	0.092060 (rank : 123)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	156	Target Neighborhood Hits	255	Shared Neighborhood Hits	41
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

SNX18_HUMAN
NC score	0.091691 (rank : 124)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	156	Target Neighborhood Hits	207	Shared Neighborhood Hits	50
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

OSTF1_HUMAN
NC score	0.090947 (rank : 125)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	156	Target Neighborhood Hits	466	Shared Neighborhood Hits	67
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

CUTL1_MOUSE
NC score	0.090840 (rank : 126)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	156	Target Neighborhood Hits	1620	Shared Neighborhood Hits	69
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CRK_HUMAN
NC score	0.089853 (rank : 127)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	156	Target Neighborhood Hits	308	Shared Neighborhood Hits	59
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CUTL1_HUMAN
NC score	0.089824 (rank : 128)	θ value	0.0961366 (rank : 38)
Query Neighborhood Hits	156	Target Neighborhood Hits	1574	Shared Neighborhood Hits	69
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

ECT2_MOUSE
NC score	0.089649 (rank : 129)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	156	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

OSTF1_MOUSE
NC score	0.089235 (rank : 130)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	156	Target Neighborhood Hits	467	Shared Neighborhood Hits	67
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

STIM1_HUMAN
NC score	0.089225 (rank : 131)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	156	Target Neighborhood Hits	665	Shared Neighborhood Hits	58
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
NC score	0.089086 (rank : 132)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	156	Target Neighborhood Hits	660	Shared Neighborhood Hits	56
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

PEX13_MOUSE
NC score	0.088842 (rank : 133)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	156	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

ARHGA_HUMAN
NC score	0.088662 (rank : 134)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	156	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

MCF2_HUMAN
NC score	0.088392 (rank : 135)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	156	Target Neighborhood Hits	166	Shared Neighborhood Hits	32
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

XE7_HUMAN
NC score	0.088269 (rank : 136)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	156	Target Neighborhood Hits	738	Shared Neighborhood Hits	61
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ARHG1_HUMAN
NC score	0.087659 (rank : 137)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	156	Target Neighborhood Hits	176	Shared Neighborhood Hits	22
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

PEX13_HUMAN
NC score	0.087300 (rank : 138)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	156	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

ECT2_HUMAN
NC score	0.087223 (rank : 139)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	156	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

RIMB2_MOUSE
NC score	0.086926 (rank : 140)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	156	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ARHGA_MOUSE
NC score	0.086643 (rank : 141)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	156	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGC_HUMAN
NC score	0.086592 (rank : 142)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	156	Target Neighborhood Hits	351	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.086221 (rank : 143)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	156	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

RGNEF_MOUSE
NC score	0.085992 (rank : 144)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	156	Target Neighborhood Hits	641	Shared Neighborhood Hits	60
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ARHGB_HUMAN
NC score	0.085740 (rank : 145)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	156	Target Neighborhood Hits	375	Shared Neighborhood Hits	27
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SM1L2_HUMAN
NC score	0.083734 (rank : 146)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	156	Target Neighborhood Hits	1019	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC3_HUMAN
NC score	0.083502 (rank : 147)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	156	Target Neighborhood Hits	1186	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
NC score	0.083414 (rank : 148)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	156	Target Neighborhood Hits	1187	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SYCP1_HUMAN
NC score	0.082981 (rank : 149)	θ value	0.0431538 (rank : 33)
Query Neighborhood Hits	156	Target Neighborhood Hits	1313	Shared Neighborhood Hits	69
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CT032_HUMAN
NC score	0.081139 (rank : 150)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	156	Target Neighborhood Hits	235	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

RIMB1_MOUSE
NC score	0.081080 (rank : 151)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	156	Target Neighborhood Hits	1376	Shared Neighborhood Hits	103
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SM1L2_MOUSE
NC score	0.081077 (rank : 152)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	156	Target Neighborhood Hits	918	Shared Neighborhood Hits	65
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

AHI1_HUMAN
NC score	0.081019 (rank : 153)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	156	Target Neighborhood Hits	537	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

FGD4_HUMAN
NC score	0.080819 (rank : 154)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	156	Target Neighborhood Hits	219	Shared Neighborhood Hits	34
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
NC score	0.080601 (rank : 155)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	156	Target Neighborhood Hits	227	Shared Neighborhood Hits	30
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

HAPIP_HUMAN
NC score	0.079699 (rank : 156)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	156	Target Neighborhood Hits	350	Shared Neighborhood Hits	47
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

NOXO1_MOUSE
NC score	0.079534 (rank : 157)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	156	Target Neighborhood Hits	114	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

SPTA2_HUMAN
NC score	0.079132 (rank : 158)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	156	Target Neighborhood Hits	888	Shared Neighborhood Hits	104
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

AHI1_MOUSE
NC score	0.078946 (rank : 159)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	156	Target Neighborhood Hits	496	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

CCD46_HUMAN
NC score	0.078091 (rank : 160)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	156	Target Neighborhood Hits	1430	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

TACC2_HUMAN
NC score	0.077703 (rank : 161)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	156	Target Neighborhood Hits	856	Shared Neighborhood Hits	64
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

NPHP1_MOUSE
NC score	0.077266 (rank : 162)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	156	Target Neighborhood Hits	267	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

FGD3_MOUSE
NC score	0.076442 (rank : 163)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	156	Target Neighborhood Hits	257	Shared Neighborhood Hits	25
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

GNRP_MOUSE
NC score	0.076440 (rank : 164)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	156	Target Neighborhood Hits	191	Shared Neighborhood Hits	27
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

ARHG1_MOUSE
NC score	0.076149 (rank : 165)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	156	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

RBP24_HUMAN
NC score	0.075628 (rank : 166)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	156	Target Neighborhood Hits	1559	Shared Neighborhood Hits	80
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.075525 (rank : 167)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	156	Target Neighborhood Hits	1558	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

PLCG1_MOUSE
NC score	0.075345 (rank : 168)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	156	Target Neighborhood Hits	314	Shared Neighborhood Hits	49
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

RAD50_HUMAN
NC score	0.075002 (rank : 169)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	156	Target Neighborhood Hits	1317	Shared Neighborhood Hits	71
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

FGD2_HUMAN
NC score	0.074765 (rank : 170)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	156	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

ARHG2_MOUSE
NC score	0.073683 (rank : 171)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	156	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

CCD91_MOUSE
NC score	0.073324 (rank : 172)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	156	Target Neighborhood Hits	699	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

RAD50_MOUSE
NC score	0.073308 (rank : 173)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	156	Target Neighborhood Hits	1366	Shared Neighborhood Hits	73
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RABE1_HUMAN
NC score	0.073277 (rank : 174)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	156	Target Neighborhood Hits	1104	Shared Neighborhood Hits	66
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

PLCG1_HUMAN
NC score	0.073168 (rank : 175)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	156	Target Neighborhood Hits	293	Shared Neighborhood Hits	47
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

HOOK1_HUMAN
NC score	0.072907 (rank : 176)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	156	Target Neighborhood Hits	942	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

CCD46_MOUSE
NC score	0.072746 (rank : 177)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	156	Target Neighborhood Hits	1405	Shared Neighborhood Hits	75
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

ARHG2_HUMAN
NC score	0.072628 (rank : 178)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	156	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

NPHP1_HUMAN
NC score	0.072104 (rank : 179)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	156	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

TMF1_HUMAN
NC score	0.071981 (rank : 180)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	156	Target Neighborhood Hits	987	Shared Neighborhood Hits	68
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

EP15_HUMAN
NC score	0.071673 (rank : 181)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	156	Target Neighborhood Hits	1021	Shared Neighborhood Hits	64
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

STS2_HUMAN
NC score	0.071672 (rank : 182)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	156	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

FGD3_HUMAN
NC score	0.071421 (rank : 183)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	156	Target Neighborhood Hits	249	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD2_MOUSE
NC score	0.071316 (rank : 184)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	156	Target Neighborhood Hits	163	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

SMC4_MOUSE
NC score	0.071207 (rank : 185)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	156	Target Neighborhood Hits	830	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

EFS_MOUSE
NC score	0.071025 (rank : 186)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	156	Target Neighborhood Hits	389	Shared Neighborhood Hits	58
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

CCD91_HUMAN
NC score	0.071020 (rank : 187)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	156	Target Neighborhood Hits	868	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

SMC4_HUMAN
NC score	0.070980 (rank : 188)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	156	Target Neighborhood Hits	937	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

EEA1_MOUSE
NC score	0.070931 (rank : 189)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	156	Target Neighborhood Hits	1637	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

LBC_HUMAN
NC score	0.070891 (rank : 190)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	156	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

RABE1_MOUSE
NC score	0.070315 (rank : 191)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	156	Target Neighborhood Hits	1105	Shared Neighborhood Hits	67
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

BCAR1_MOUSE
NC score	0.070293 (rank : 192)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	156	Target Neighborhood Hits	438	Shared Neighborhood Hits	63
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

TTC3_HUMAN
NC score	0.070050 (rank : 193)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	156	Target Neighborhood Hits	664	Shared Neighborhood Hits	58
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

SYCP1_MOUSE
NC score	0.069885 (rank : 194)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	156	Target Neighborhood Hits	1456	Shared Neighborhood Hits	75
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

FLIP1_MOUSE
NC score	0.069784 (rank : 195)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	156	Target Neighborhood Hits	1176	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

EP15_MOUSE
NC score	0.069605 (rank : 196)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	156	Target Neighborhood Hits	820	Shared Neighborhood Hits	57
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GNRP_HUMAN
NC score	0.069590 (rank : 197)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	156	Target Neighborhood Hits	239	Shared Neighborhood Hits	33
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

CENPF_HUMAN
NC score	0.069323 (rank : 198)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	156	Target Neighborhood Hits	1932	Shared Neighborhood Hits	78
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

BCAR1_HUMAN
NC score	0.069256 (rank : 199)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	156	Target Neighborhood Hits	554	Shared Neighborhood Hits	62
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SWP70_HUMAN
NC score	0.069228 (rank : 200)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	156	Target Neighborhood Hits	973	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PLCG2_HUMAN
NC score	0.068878 (rank : 201)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	156	Target Neighborhood Hits	280	Shared Neighborhood Hits	45
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

GOGA2_MOUSE
NC score	0.068639 (rank : 202)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	156	Target Neighborhood Hits	944	Shared Neighborhood Hits	63
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

CP135_MOUSE
NC score	0.068560 (rank : 203)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	156	Target Neighborhood Hits	1278	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CE290_HUMAN
NC score	0.068389 (rank : 204)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	156	Target Neighborhood Hits	1553	Shared Neighborhood Hits	76
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

IF3A_HUMAN
NC score	0.068124 (rank : 205)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	156	Target Neighborhood Hits	875	Shared Neighborhood Hits	74
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

TPR_HUMAN
NC score	0.067907 (rank : 206)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	156	Target Neighborhood Hits	1921	Shared Neighborhood Hits	78
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SPTA1_HUMAN
NC score	0.067591 (rank : 207)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	156	Target Neighborhood Hits	748	Shared Neighborhood Hits	98
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

IF3A_MOUSE
NC score	0.067582 (rank : 208)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	156	Target Neighborhood Hits	871	Shared Neighborhood Hits	71
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

PEPL_HUMAN
NC score	0.067375 (rank : 209)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	156	Target Neighborhood Hits	1141	Shared Neighborhood Hits	65
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

NUMA1_HUMAN
NC score	0.067291 (rank : 210)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	156	Target Neighborhood Hits	1523	Shared Neighborhood Hits	81
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

MFAP1_MOUSE
NC score	0.067284 (rank : 211)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	156	Target Neighborhood Hits	353	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

CCD19_HUMAN
NC score	0.067205 (rank : 212)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	156	Target Neighborhood Hits	639	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

FLIP1_HUMAN
NC score	0.067176 (rank : 213)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	156	Target Neighborhood Hits	1405	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FGD1_HUMAN
NC score	0.067142 (rank : 214)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	156	Target Neighborhood Hits	367	Shared Neighborhood Hits	32
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

CP250_HUMAN
NC score	0.066840 (rank : 215)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	156	Target Neighborhood Hits	1805	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

NOXO1_HUMAN
NC score	0.066753 (rank : 216)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	156	Target Neighborhood Hits	100	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

BIN1_HUMAN
NC score	0.066725 (rank : 217)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	156	Target Neighborhood Hits	335	Shared Neighborhood Hits	52
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

EFS_HUMAN
NC score	0.066658 (rank : 218)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	156	Target Neighborhood Hits	348	Shared Neighborhood Hits	55
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

SAS6_MOUSE
NC score	0.066535 (rank : 219)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	156	Target Neighborhood Hits	931	Shared Neighborhood Hits	59
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

P85A_HUMAN
NC score	0.066455 (rank : 220)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	156	Target Neighborhood Hits	479	Shared Neighborhood Hits	66
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

INCE_MOUSE
NC score	0.066339 (rank : 221)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	156	Target Neighborhood Hits	903	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

SRGP2_MOUSE
NC score	0.066181 (rank : 222)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	156	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

HOOK1_MOUSE
NC score	0.066180 (rank : 223)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	156	Target Neighborhood Hits	910	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

FYCO1_MOUSE
NC score	0.066165 (rank : 224)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	156	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

MYO1F_MOUSE
NC score	0.066146 (rank : 225)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	156	Target Neighborhood Hits	262	Shared Neighborhood Hits	67
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

CEP63_HUMAN
NC score	0.066135 (rank : 226)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	156	Target Neighborhood Hits	1005	Shared Neighborhood Hits	63
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CING_MOUSE
NC score	0.066115 (rank : 227)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	156	Target Neighborhood Hits	1432	Shared Neighborhood Hits	70
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CN145_MOUSE
NC score	0.066031 (rank : 228)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	156	Target Neighborhood Hits	916	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

FGD1_MOUSE
NC score	0.065993 (rank : 229)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	156	Target Neighborhood Hits	387	Shared Neighborhood Hits	30
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

TEX9_MOUSE
NC score	0.065697 (rank : 230)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	156	Target Neighborhood Hits	581	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

CCD27_HUMAN
NC score	0.065665 (rank : 231)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	156	Target Neighborhood Hits	594	Shared Neighborhood Hits	52
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

MYO1F_HUMAN
NC score	0.065472 (rank : 232)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	156	Target Neighborhood Hits	275	Shared Neighborhood Hits	67
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

SRGP2_HUMAN
NC score	0.065351 (rank : 233)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	156	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

MD1L1_HUMAN
NC score	0.065288 (rank : 234)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	156	Target Neighborhood Hits	893	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

GOGB1_HUMAN
NC score	0.065112 (rank : 235)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	156	Target Neighborhood Hits	2297	Shared Neighborhood Hits	85
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CF060_HUMAN
NC score	0.065098 (rank : 236)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	156	Target Neighborhood Hits	1270	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

GOGA6_HUMAN
NC score	0.065067 (rank : 237)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	156	Target Neighborhood Hits	1007	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CNTRB_MOUSE
NC score	0.065046 (rank : 238)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	156	Target Neighborhood Hits	1029	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

LRC45_HUMAN
NC score	0.064996 (rank : 239)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	156	Target Neighborhood Hits	933	Shared Neighborhood Hits	64
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

FGD6_MOUSE
NC score	0.064955 (rank : 240)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	156	Target Neighborhood Hits	282	Shared Neighborhood Hits	33
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

SMCE1_MOUSE
NC score	0.064880 (rank : 241)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	156	Target Neighborhood Hits	409	Shared Neighborhood Hits	30
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

ASPP2_HUMAN
NC score	0.064732 (rank : 242)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	156	Target Neighborhood Hits	1156	Shared Neighborhood Hits	98
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ASPP1_MOUSE
NC score	0.064695 (rank : 243)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	156	Target Neighborhood Hits	1244	Shared Neighborhood Hits	101
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_HUMAN
NC score	0.064412 (rank : 244)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	156	Target Neighborhood Hits	956	Shared Neighborhood Hits	95
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

EP15R_MOUSE
NC score	0.064409 (rank : 245)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	156	Target Neighborhood Hits	1135	Shared Neighborhood Hits	58
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

GCC2_MOUSE
NC score	0.064400 (rank : 246)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	156	Target Neighborhood Hits	1619	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

AZI1_HUMAN
NC score	0.064161 (rank : 247)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	156	Target Neighborhood Hits	1000	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

ERC2_MOUSE
NC score	0.064117 (rank : 248)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	156	Target Neighborhood Hits	1166	Shared Neighborhood Hits	75
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

KMHN1_HUMAN
NC score	0.063985 (rank : 249)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	156	Target Neighborhood Hits	950	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

CEP55_MOUSE
NC score	0.063902 (rank : 250)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	156	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

TCGAP_MOUSE
NC score	0.063871 (rank : 251)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	156	Target Neighborhood Hits	409	Shared Neighborhood Hits	49
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

P85A_MOUSE
NC score	0.063746 (rank : 252)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	156	Target Neighborhood Hits	435	Shared Neighborhood Hits	60
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

TRHY_HUMAN
NC score	0.063712 (rank : 253)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	156	Target Neighborhood Hits	1385	Shared Neighborhood Hits	71
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CALD1_HUMAN
NC score	0.063708 (rank : 254)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	156	Target Neighborhood Hits	959	Shared Neighborhood Hits	61
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

EP15R_HUMAN
NC score	0.063416 (rank : 255)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	156	Target Neighborhood Hits	1083	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

GOGA4_HUMAN
NC score	0.063382 (rank : 256)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	156	Target Neighborhood Hits	2034	Shared Neighborhood Hits	87
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

SPTA1_MOUSE
NC score	0.063347 (rank : 257)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	156	Target Neighborhood Hits	675	Shared Neighborhood Hits	91
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SAS6_HUMAN
NC score	0.063328 (rank : 258)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	156	Target Neighborhood Hits	791	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

BRE1A_HUMAN
NC score	0.063304 (rank : 259)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	156	Target Neighborhood Hits	1071	Shared Neighborhood Hits	63
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

MYO1E_HUMAN
NC score	0.063154 (rank : 260)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	156	Target Neighborhood Hits	293	Shared Neighborhood Hits	68
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

GOGA4_MOUSE
NC score	0.063019 (rank : 261)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	156	Target Neighborhood Hits	1939	Shared Neighborhood Hits	76
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GRAP1_HUMAN
NC score	0.062896 (rank : 262)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	156	Target Neighborhood Hits	944	Shared Neighborhood Hits	67
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HMMR_HUMAN
NC score	0.062868 (rank : 263)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	156	Target Neighborhood Hits	1082	Shared Neighborhood Hits	66
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

INVO_HUMAN
NC score	0.062857 (rank : 264)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	156	Target Neighborhood Hits	636	Shared Neighborhood Hits	57
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

PCNT_HUMAN
NC score	0.062525 (rank : 265)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	156	Target Neighborhood Hits	1551	Shared Neighborhood Hits	81
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

EEA1_HUMAN
NC score	0.062466 (rank : 266)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	156	Target Neighborhood Hits	1796	Shared Neighborhood Hits	81
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CCDC6_HUMAN
NC score	0.062464 (rank : 267)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	156	Target Neighborhood Hits	723	Shared Neighborhood Hits	61
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCD96_MOUSE
NC score	0.062413 (rank : 268)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	156	Target Neighborhood Hits	704	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

PEPL_MOUSE
NC score	0.062397 (rank : 269)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	156	Target Neighborhood Hits	1105	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RB6I2_HUMAN
NC score	0.062318 (rank : 270)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	156	Target Neighborhood Hits	1584	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

PIBF1_HUMAN
NC score	0.062263 (rank : 271)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	156	Target Neighborhood Hits	1041	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

RB6I2_MOUSE
NC score	0.062168 (rank : 272)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	156	Target Neighborhood Hits	1433	Shared Neighborhood Hits	70
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

GOGA1_MOUSE
NC score	0.062153 (rank : 273)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	156	Target Neighborhood Hits	994	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

AZI1_MOUSE
NC score	0.062148 (rank : 274)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	156	Target Neighborhood Hits	990	Shared Neighborhood Hits	70
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

NUF2_MOUSE
NC score	0.062102 (rank : 275)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	156	Target Neighborhood Hits	585	Shared Neighborhood Hits	62
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

UACA_HUMAN
NC score	0.062097 (rank : 276)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	156	Target Neighborhood Hits	1622	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AKAP9_HUMAN
NC score	0.061969 (rank : 277)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	156	Target Neighborhood Hits	1710	Shared Neighborhood Hits	77
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

INCE_HUMAN
NC score	0.061941 (rank : 278)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	156	Target Neighborhood Hits	978	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

CI093_HUMAN
NC score	0.061848 (rank : 279)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	156	Target Neighborhood Hits	1088	Shared Neighborhood Hits	65
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

LRC45_MOUSE
NC score	0.061834 (rank : 280)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	156	Target Neighborhood Hits	959	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

GAS8_HUMAN
NC score	0.061754 (rank : 281)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	156	Target Neighborhood Hits	819	Shared Neighborhood Hits	61
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

TNIP3_HUMAN
NC score	0.061740 (rank : 282)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	156	Target Neighborhood Hits	511	Shared Neighborhood Hits	53
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

P85B_HUMAN
NC score	0.061726 (rank : 283)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	156	Target Neighborhood Hits	543	Shared Neighborhood Hits	69
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

ANR26_HUMAN
NC score	0.061632 (rank : 284)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	156	Target Neighborhood Hits	1614	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CP250_MOUSE
NC score	0.061590 (rank : 285)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	156	Target Neighborhood Hits	1583	Shared Neighborhood Hits	77
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

IFT74_HUMAN
NC score	0.061540 (rank : 286)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	156	Target Neighborhood Hits	949	Shared Neighborhood Hits	57
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

K0555_HUMAN
NC score	0.061377 (rank : 287)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	156	Target Neighborhood Hits	880	Shared Neighborhood Hits	63
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

CENPE_HUMAN
NC score	0.061376 (rank : 288)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	156	Target Neighborhood Hits	2060	Shared Neighborhood Hits	87
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MD1L1_MOUSE
NC score	0.061231 (rank : 289)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	156	Target Neighborhood Hits	1001	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

RBCC1_HUMAN
NC score	0.061201 (rank : 290)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	156	Target Neighborhood Hits	1023	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CASL_HUMAN
NC score	0.061060 (rank : 291)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	156	Target Neighborhood Hits	259	Shared Neighborhood Hits	59
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

OFD1_HUMAN
NC score	0.060914 (rank : 292)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	156	Target Neighborhood Hits	753	Shared Neighborhood Hits	60
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

CP135_HUMAN
NC score	0.060856 (rank : 293)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	156	Target Neighborhood Hits	1290	Shared Neighborhood Hits	66
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

FARP2_MOUSE
NC score	0.060831 (rank : 294)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	156	Target Neighborhood Hits	209	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

OPTN_HUMAN
NC score	0.060793 (rank : 295)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	156	Target Neighborhood Hits	827	Shared Neighborhood Hits	59
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

TRIPB_HUMAN
NC score	0.060748 (rank : 296)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	156	Target Neighborhood Hits	1587	Shared Neighborhood Hits	74
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CR034_HUMAN
NC score	0.060714 (rank : 297)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	156	Target Neighborhood Hits	538	Shared Neighborhood Hits	59
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CCD96_HUMAN
NC score	0.060711 (rank : 298)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	156	Target Neighborhood Hits	595	Shared Neighborhood Hits	55
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CING_HUMAN
NC score	0.060682 (rank : 299)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	156	Target Neighborhood Hits	1275	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CI039_HUMAN
NC score	0.060651 (rank : 300)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	156	Target Neighborhood Hits	1171	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

BRE1A_MOUSE
NC score	0.060499 (rank : 301)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	156	Target Neighborhood Hits	1025	Shared Neighborhood Hits	63
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

AMPH_HUMAN
NC score	0.060469 (rank : 302)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	156	Target Neighborhood Hits	455	Shared Neighborhood Hits	56
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

IFT74_MOUSE
NC score	0.060468 (rank : 303)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	156	Target Neighborhood Hits	939	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

NIN_HUMAN
NC score	0.060406 (rank : 304)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	156	Target Neighborhood Hits	1416	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CE152_HUMAN
NC score	0.060383 (rank : 305)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	156	Target Neighborhood Hits	976	Shared Neighborhood Hits	62
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

GAS8_MOUSE
NC score	0.060379 (rank : 306)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	156	Target Neighborhood Hits	622	Shared Neighborhood Hits	54
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GRAP1_MOUSE
NC score	0.060346 (rank : 307)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	156	Target Neighborhood Hits	1234	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

SDCG8_HUMAN
NC score	0.060341 (rank : 308)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	156	Target Neighborhood Hits	1002	Shared Neighborhood Hits	61
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

GOGA3_MOUSE
NC score	0.060279 (rank : 309)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	156	Target Neighborhood Hits	1437	Shared Neighborhood Hits	67
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

P85B_MOUSE
NC score	0.060260 (rank : 310)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	156	Target Neighborhood Hits	519	Shared Neighborhood Hits	70
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CCD21_MOUSE
NC score	0.060204 (rank : 311)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	156	Target Neighborhood Hits	1135	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

RHG04_HUMAN
NC score	0.060173 (rank : 312)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	156	Target Neighborhood Hits	307	Shared Neighborhood Hits	56
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

TAXB1_HUMAN
NC score	0.060169 (rank : 313)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	156	Target Neighborhood Hits	829	Shared Neighborhood Hits	61
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

GCC1_MOUSE
NC score	0.060164 (rank : 314)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	156	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

SMCE1_HUMAN
NC score	0.060119 (rank : 315)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	156	Target Neighborhood Hits	272	Shared Neighborhood Hits	26
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SWP70_MOUSE
NC score	0.060114 (rank : 316)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	156	Target Neighborhood Hits	1097	Shared Neighborhood Hits	68
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ANM2_HUMAN
NC score	0.060102 (rank : 317)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	156	Target Neighborhood Hits	175	Shared Neighborhood Hits	45
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

CROCC_HUMAN
NC score	0.060078 (rank : 318)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	156	Target Neighborhood Hits	1409	Shared Neighborhood Hits	75
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ERC2_HUMAN
NC score	0.060050 (rank : 319)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	156	Target Neighborhood Hits	1156	Shared Neighborhood Hits	71
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

HMMR_MOUSE
NC score	0.059965 (rank : 320)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	156	Target Neighborhood Hits	1178	Shared Neighborhood Hits	73
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GOGA2_HUMAN
NC score	0.059931 (rank : 321)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	156	Target Neighborhood Hits	856	Shared Neighborhood Hits	60
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

LUZP1_MOUSE
NC score	0.059880 (rank : 322)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	156	Target Neighborhood Hits	940	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

IFT81_HUMAN
NC score	0.059873 (rank : 323)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	156	Target Neighborhood Hits	893	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

UACA_MOUSE
NC score	0.059778 (rank : 324)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	156	Target Neighborhood Hits	1620	Shared Neighborhood Hits	78
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GOGA1_HUMAN
NC score	0.059766 (rank : 325)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	156	Target Neighborhood Hits	1222	Shared Neighborhood Hits	66
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

REST_HUMAN
NC score	0.059725 (rank : 326)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	156	Target Neighborhood Hits	1605	Shared Neighborhood Hits	71
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

IFT81_MOUSE
NC score	0.059709 (rank : 327)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	156	Target Neighborhood Hits	959	Shared Neighborhood Hits	60
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

STS1_HUMAN
NC score	0.059692 (rank : 328)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	156	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

CCD11_MOUSE
NC score	0.059643 (rank : 329)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	156	Target Neighborhood Hits	498	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

KTN1_MOUSE
NC score	0.059531 (rank : 330)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	156	Target Neighborhood Hits	1324	Shared Neighborhood Hits	69
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

DYNA_HUMAN
NC score	0.059529 (rank : 331)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	156	Target Neighborhood Hits	1194	Shared Neighborhood Hits	68
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

EVPL_HUMAN
NC score	0.059441 (rank : 332)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	156	Target Neighborhood Hits	895	Shared Neighborhood Hits	60
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

CCD39_MOUSE
NC score	0.059423 (rank : 333)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	156	Target Neighborhood Hits	1026	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCHCR_MOUSE
NC score	0.059362 (rank : 334)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	156	Target Neighborhood Hits	932	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

NIN_MOUSE
NC score	0.059341 (rank : 335)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	156	Target Neighborhood Hits	1376	Shared Neighborhood Hits	71
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

RBCC1_MOUSE
NC score	0.059232 (rank : 336)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	156	Target Neighborhood Hits	1048	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

DESP_HUMAN
NC score	0.059088 (rank : 337)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	156	Target Neighborhood Hits	1470	Shared Neighborhood Hits	74
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

TSC1_HUMAN
NC score	0.059085 (rank : 338)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	156	Target Neighborhood Hits	765	Shared Neighborhood Hits	54
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

FGD6_HUMAN
NC score	0.059079 (rank : 339)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	156	Target Neighborhood Hits	237	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

KTN1_HUMAN
NC score	0.059005 (rank : 340)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	156	Target Neighborhood Hits	1197	Shared Neighborhood Hits	65
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CASL_MOUSE
NC score	0.058801 (rank : 341)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	156	Target Neighborhood Hits	225	Shared Neighborhood Hits	52
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CT096_HUMAN
NC score	0.058785 (rank : 342)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	156	Target Neighborhood Hits	438	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CYLN2_MOUSE
NC score	0.058723 (rank : 343)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	156	Target Neighborhood Hits	1002	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

GOGA5_MOUSE
NC score	0.058617 (rank : 344)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	156	Target Neighborhood Hits	1434	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

HIP1_HUMAN
NC score	0.058604 (rank : 345)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	156	Target Neighborhood Hits	1016	Shared Neighborhood Hits	65
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

EBP2_HUMAN
NC score	0.058499 (rank : 346)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	156	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	Q99848, Q96A66	Gene names	EBNA1BP2, EBP2
Domain Architecture
Description	Probable rRNA-processing protein EBP2 (EBNA1-binding protein 2) (Nucleolar protein p40).

PCNT_MOUSE
NC score	0.058412 (rank : 347)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	156	Target Neighborhood Hits	1207	Shared Neighborhood Hits	68
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

FNBP2_HUMAN
NC score	0.058312 (rank : 348)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	156	Target Neighborhood Hits	432	Shared Neighborhood Hits	75
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

CCD41_HUMAN
NC score	0.058211 (rank : 349)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	156	Target Neighborhood Hits	1139	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD39_HUMAN
NC score	0.058016 (rank : 350)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	156	Target Neighborhood Hits	868	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CJ118_MOUSE
NC score	0.057908 (rank : 351)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	156	Target Neighborhood Hits	1132	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

DYNA_MOUSE
NC score	0.057884 (rank : 352)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	156	Target Neighborhood Hits	1084	Shared Neighborhood Hits	67
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

CCD11_HUMAN
NC score	0.057849 (rank : 353)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	156	Target Neighborhood Hits	822	Shared Neighborhood Hits	65
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD41_MOUSE
NC score	0.057845 (rank : 354)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	156	Target Neighborhood Hits	1399	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD13_HUMAN
NC score	0.057797 (rank : 355)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	156	Target Neighborhood Hits	721	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

RUFY2_HUMAN
NC score	0.057789 (rank : 356)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	156	Target Neighborhood Hits	1208	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

GOGA3_HUMAN
NC score	0.057638 (rank : 357)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	156	Target Neighborhood Hits	1317	Shared Neighborhood Hits	65
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GCC1_HUMAN
NC score	0.057628 (rank : 358)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	156	Target Neighborhood Hits	887	Shared Neighborhood Hits	58
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

NAF1_HUMAN
NC score	0.057613 (rank : 359)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	156	Target Neighborhood Hits	937	Shared Neighborhood Hits	64
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

EVPL_MOUSE
NC score	0.057571 (rank : 360)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	156	Target Neighborhood Hits	952	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

CK5P2_HUMAN
NC score	0.057452 (rank : 361)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	156	Target Neighborhood Hits	1433	Shared Neighborhood Hits	72
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CCD21_HUMAN
NC score	0.057417 (rank : 362)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	156	Target Neighborhood Hits	1228	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

BPAEA_MOUSE
NC score	0.057411 (rank : 363)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	156	Target Neighborhood Hits	1480	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MY18A_HUMAN
NC score	0.057318 (rank : 364)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	156	Target Neighborhood Hits	1929	Shared Neighborhood Hits	79
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ZN291_HUMAN
NC score	0.057263 (rank : 365)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	156	Target Neighborhood Hits	647	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

MFAP1_HUMAN
NC score	0.057241 (rank : 366)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	156	Target Neighborhood Hits	321	Shared Neighborhood Hits	44
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

IASPP_HUMAN
NC score	0.057101 (rank : 367)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	156	Target Neighborhood Hits	688	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TPM3_HUMAN
NC score	0.057041 (rank : 368)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	156	Target Neighborhood Hits	689	Shared Neighborhood Hits	61
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

CT2NL_HUMAN
NC score	0.057015 (rank : 369)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	156	Target Neighborhood Hits	1059	Shared Neighborhood Hits	66
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MYH11_HUMAN
NC score	0.057000 (rank : 370)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	156	Target Neighborhood Hits	1806	Shared Neighborhood Hits	89
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

KMHN1_MOUSE
NC score	0.056997 (rank : 371)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	156	Target Neighborhood Hits	949	Shared Neighborhood Hits	65
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

MYH8_HUMAN
NC score	0.056808 (rank : 372)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	156	Target Neighborhood Hits	1610	Shared Neighborhood Hits	79
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CF182_MOUSE
NC score	0.056801 (rank : 373)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	156	Target Neighborhood Hits	551	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

ANM2_MOUSE
NC score	0.056786 (rank : 374)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	156	Target Neighborhood Hits	175	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

KNTC2_HUMAN
NC score	0.056768 (rank : 375)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	156	Target Neighborhood Hits	673	Shared Neighborhood Hits	58
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

BIN1_MOUSE
NC score	0.056697 (rank : 376)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	156	Target Neighborhood Hits	283	Shared Neighborhood Hits	54
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

MACOI_HUMAN
NC score	0.056689 (rank : 377)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	156	Target Neighborhood Hits	650	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

TPM3_MOUSE
NC score	0.056634 (rank : 378)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	156	Target Neighborhood Hits	676	Shared Neighborhood Hits	62
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

PPIP2_HUMAN
NC score	0.056633 (rank : 379)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	156	Target Neighborhood Hits	254	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

MYH6_MOUSE
NC score	0.056497 (rank : 380)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	156	Target Neighborhood Hits	1501	Shared Neighborhood Hits	79
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

LUZP1_HUMAN
NC score	0.056476 (rank : 381)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	156	Target Neighborhood Hits	739	Shared Neighborhood Hits	56
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

TEX9_HUMAN
NC score	0.056374 (rank : 382)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	156	Target Neighborhood Hits	541	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

NAF1_MOUSE
NC score	0.056341 (rank : 383)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	156	Target Neighborhood Hits	852	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PLEC1_HUMAN
NC score	0.056319 (rank : 384)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	156	Target Neighborhood Hits	1326	Shared Neighborhood Hits	69
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

FARP1_HUMAN
NC score	0.056296 (rank : 385)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	156	Target Neighborhood Hits	241	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

CEP55_HUMAN
NC score	0.056188 (rank : 386)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	156	Target Neighborhood Hits	504	Shared Neighborhood Hits	50
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

PININ_HUMAN
NC score	0.056118 (rank : 387)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	156	Target Neighborhood Hits	753	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

HOOK3_MOUSE
NC score	0.056086 (rank : 388)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	156	Target Neighborhood Hits	1007	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HOOK3_HUMAN
NC score	0.056064 (rank : 389)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	156	Target Neighborhood Hits	1070	Shared Neighborhood Hits	67
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CROCC_MOUSE
NC score	0.056041 (rank : 390)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	156	Target Neighborhood Hits	1460	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RUFY1_MOUSE
NC score	0.055963 (rank : 391)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	156	Target Neighborhood Hits	765	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

SPN90_MOUSE
NC score	0.055890 (rank : 392)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	156	Target Neighborhood Hits	157	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

TCRG1_HUMAN
NC score	0.055868 (rank : 393)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	156	Target Neighborhood Hits	929	Shared Neighborhood Hits	55
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TPM1_HUMAN
NC score	0.055814 (rank : 394)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	156	Target Neighborhood Hits	716	Shared Neighborhood Hits	60
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

SRGP1_HUMAN
NC score	0.055814 (rank : 395)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	156	Target Neighborhood Hits	390	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

TPM2_HUMAN
NC score	0.055777 (rank : 396)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	156	Target Neighborhood Hits	677	Shared Neighborhood Hits	59
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

FARP2_HUMAN
NC score	0.055704 (rank : 397)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	156	Target Neighborhood Hits	240	Shared Neighborhood Hits	22
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

TPM1_MOUSE
NC score	0.055694 (rank : 398)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	156	Target Neighborhood Hits	729	Shared Neighborhood Hits	61
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

RUFY1_HUMAN
NC score	0.055658 (rank : 399)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	156	Target Neighborhood Hits	848	Shared Neighborhood Hits	60
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

C102B_HUMAN
NC score	0.055620 (rank : 400)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	156	Target Neighborhood Hits	542	Shared Neighborhood Hits	56
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

FYCO1_HUMAN
NC score	0.055555 (rank : 401)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	156	Target Neighborhood Hits	1149	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

TCRG1_MOUSE
NC score	0.055551 (rank : 402)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	156	Target Neighborhood Hits	947	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

REST_MOUSE
NC score	0.055490 (rank : 403)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	156	Target Neighborhood Hits	1506	Shared Neighborhood Hits	66
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TAXB1_MOUSE
NC score	0.055322 (rank : 404)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	156	Target Neighborhood Hits	886	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

MACOI_MOUSE
NC score	0.055216 (rank : 405)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	156	Target Neighborhood Hits	620	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

TPM2_MOUSE
NC score	0.055186 (rank : 406)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	156	Target Neighborhood Hits	676	Shared Neighborhood Hits	59
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

IASPP_MOUSE
NC score	0.055119 (rank : 407)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	156	Target Neighborhood Hits	1024	Shared Neighborhood Hits	65
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CNTRB_HUMAN
NC score	0.055029 (rank : 408)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	156	Target Neighborhood Hits	690	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

SDCG8_MOUSE
NC score	0.055028 (rank : 409)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	156	Target Neighborhood Hits	886	Shared Neighborhood Hits	60
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CJ118_HUMAN
NC score	0.055018 (rank : 410)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	156	Target Neighborhood Hits	937	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

RRBP1_MOUSE
NC score	0.055012 (rank : 411)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	156	Target Neighborhood Hits	1650	Shared Neighborhood Hits	71
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CYLN2_HUMAN
NC score	0.054963 (rank : 412)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	156	Target Neighborhood Hits	1004	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CK5P2_MOUSE
NC score	0.054955 (rank : 413)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	156	Target Neighborhood Hits	1151	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

BRE1B_HUMAN
NC score	0.054931 (rank : 414)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	156	Target Neighborhood Hits	1040	Shared Neighborhood Hits	61
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

MYH9_MOUSE
NC score	0.054852 (rank : 415)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	156	Target Neighborhood Hits	1829	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

KNTC2_MOUSE
NC score	0.054831 (rank : 416)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	156	Target Neighborhood Hits	692	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

MYH10_MOUSE
NC score	0.054825 (rank : 417)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	156	Target Neighborhood Hits	1612	Shared Neighborhood Hits	80
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

BCR_HUMAN
NC score	0.054732 (rank : 418)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	156	Target Neighborhood Hits	204	Shared Neighborhood Hits	24
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

PPIP2_MOUSE
NC score	0.054689 (rank : 419)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	156	Target Neighborhood Hits	308	Shared Neighborhood Hits	51
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

TCGAP_HUMAN
NC score	0.054657 (rank : 420)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	156	Target Neighborhood Hits	872	Shared Neighborhood Hits	55
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CCHCR_HUMAN
NC score	0.054632 (rank : 421)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	156	Target Neighborhood Hits	717	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

ANR26_MOUSE
NC score	0.054620 (rank : 422)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	156	Target Neighborhood Hits	1554	Shared Neighborhood Hits	66
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

LRRF2_HUMAN
NC score	0.054585 (rank : 423)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	156	Target Neighborhood Hits	791	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

NEMO_HUMAN
NC score	0.054572 (rank : 424)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	156	Target Neighborhood Hits	820	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

MYH10_HUMAN
NC score	0.054542 (rank : 425)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	156	Target Neighborhood Hits	1620	Shared Neighborhood Hits	81
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

TUFT1_HUMAN
NC score	0.054445 (rank : 426)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	156	Target Neighborhood Hits	686	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TACC3_MOUSE
NC score	0.054397 (rank : 427)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	156	Target Neighborhood Hits	607	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

GOGA5_HUMAN
NC score	0.054391 (rank : 428)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	156	Target Neighborhood Hits	1168	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

RASF8_HUMAN
NC score	0.054348 (rank : 429)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	156	Target Neighborhood Hits	469	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

OPTN_MOUSE
NC score	0.054245 (rank : 430)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	156	Target Neighborhood Hits	1120	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CEP70_HUMAN
NC score	0.054148 (rank : 431)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	156	Target Neighborhood Hits	432	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

MYH13_HUMAN
NC score	0.054122 (rank : 432)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	156	Target Neighborhood Hits	1504	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH7_HUMAN
NC score	0.053985 (rank : 433)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	156	Target Neighborhood Hits	1559	Shared Neighborhood Hits	75
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH9_HUMAN
NC score	0.053927 (rank : 434)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	156	Target Neighborhood Hits	1762	Shared Neighborhood Hits	84
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RPGR1_HUMAN
NC score	0.053772 (rank : 435)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	156	Target Neighborhood Hits	578	Shared Neighborhood Hits	50
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CR034_MOUSE
NC score	0.053669 (rank : 436)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	156	Target Neighborhood Hits	643	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

MY18A_MOUSE
NC score	0.053523 (rank : 437)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	156	Target Neighborhood Hits	1989	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CARD9_HUMAN
NC score	0.053447 (rank : 438)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	156	Target Neighborhood Hits	602	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

SPAG5_MOUSE
NC score	0.053421 (rank : 439)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	156	Target Neighborhood Hits	612	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

TPM4_MOUSE
NC score	0.053242 (rank : 440)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	156	Target Neighborhood Hits	703	Shared Neighborhood Hits	58
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

RFIP4_HUMAN
NC score	0.053181 (rank : 441)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	156	Target Neighborhood Hits	785	Shared Neighborhood Hits	56
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

NEST_HUMAN
NC score	0.053057 (rank : 442)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	156	Target Neighborhood Hits	1305	Shared Neighborhood Hits	60
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CYTSA_HUMAN
NC score	0.053031 (rank : 443)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	156	Target Neighborhood Hits	1138	Shared Neighborhood Hits	68
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CU013_HUMAN
NC score	0.053029 (rank : 444)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	156	Target Neighborhood Hits	405	Shared Neighborhood Hits	46
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

RFIP3_HUMAN
NC score	0.052941 (rank : 445)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	156	Target Neighborhood Hits	1055	Shared Neighborhood Hits	61
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

NUF2_HUMAN
NC score	0.052869 (rank : 446)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	156	Target Neighborhood Hits	661	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

MIPO1_HUMAN
NC score	0.052816 (rank : 447)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	156	Target Neighborhood Hits	486	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

ANR18_HUMAN
NC score	0.052699 (rank : 448)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	156	Target Neighborhood Hits	1106	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

RRBP1_HUMAN
NC score	0.052654 (rank : 449)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	156	Target Neighborhood Hits	1306	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SPN90_HUMAN
NC score	0.052621 (rank : 450)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	156	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

HOOK2_MOUSE
NC score	0.052602 (rank : 451)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	156	Target Neighborhood Hits	736	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

STS1_MOUSE
NC score	0.052590 (rank : 452)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	156	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

MYH11_MOUSE
NC score	0.052568 (rank : 453)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	156	Target Neighborhood Hits	1777	Shared Neighborhood Hits	79
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RABE2_MOUSE
NC score	0.052527 (rank : 454)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	156	Target Neighborhood Hits	598	Shared Neighborhood Hits	51
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

MYH6_HUMAN
NC score	0.052518 (rank : 455)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	156	Target Neighborhood Hits	1426	Shared Neighborhood Hits	70
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SF3A1_HUMAN
NC score	0.052440 (rank : 456)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	156	Target Neighborhood Hits	199	Shared Neighborhood Hits	8
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

GOG8A_HUMAN
NC score	0.052439 (rank : 457)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	156	Target Neighborhood Hits	635	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

MY18B_HUMAN
NC score	0.052389 (rank : 458)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	156	Target Neighborhood Hits	1299	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CT2NL_MOUSE
NC score	0.052281 (rank : 459)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	156	Target Neighborhood Hits	902	Shared Neighborhood Hits	61
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PININ_MOUSE
NC score	0.052215 (rank : 460)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	156	Target Neighborhood Hits	777	Shared Neighborhood Hits	54
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

BRE1B_MOUSE
NC score	0.052161 (rank : 461)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	156	Target Neighborhood Hits	970	Shared Neighborhood Hits	62
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CCD62_HUMAN
NC score	0.051947 (rank : 462)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	156	Target Neighborhood Hits	631	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CF152_HUMAN
NC score	0.051763 (rank : 463)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	156	Target Neighborhood Hits	704	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

HIP1R_MOUSE
NC score	0.051617 (rank : 464)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	156	Target Neighborhood Hits	959	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

TRAIP_MOUSE
NC score	0.051612 (rank : 465)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	156	Target Neighborhood Hits	745	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

IF2P_HUMAN
NC score	0.051462 (rank : 466)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	156	Target Neighborhood Hits	889	Shared Neighborhood Hits	65
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

SF3A1_MOUSE
NC score	0.051395 (rank : 467)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	156	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

CCD42_HUMAN
NC score	0.051387 (rank : 468)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	156	Target Neighborhood Hits	406	Shared Neighborhood Hits	47
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

MYH8_MOUSE
NC score	0.051366 (rank : 469)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	156	Target Neighborhood Hits	1600	Shared Neighborhood Hits	74
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

BICD2_MOUSE
NC score	0.051256 (rank : 470)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	156	Target Neighborhood Hits	864	Shared Neighborhood Hits	54
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

AMPH_MOUSE
NC score	0.051207 (rank : 471)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	156	Target Neighborhood Hits	291	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

TUFT1_MOUSE
NC score	0.051186 (rank : 472)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	156	Target Neighborhood Hits	732	Shared Neighborhood Hits	52
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

TACC1_MOUSE
NC score	0.051164 (rank : 473)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	156	Target Neighborhood Hits	667	Shared Neighborhood Hits	56
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

CUTL2_HUMAN
NC score	0.051141 (rank : 474)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	156	Target Neighborhood Hits	906	Shared Neighborhood Hits	53
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

TRAIP_HUMAN
NC score	0.051059 (rank : 475)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	156	Target Neighborhood Hits	780	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

CAF1A_MOUSE
NC score	0.050987 (rank : 476)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	156	Target Neighborhood Hits	736	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

MYH1_MOUSE
NC score	0.050964 (rank : 477)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	156	Target Neighborhood Hits	1461	Shared Neighborhood Hits	76
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_MOUSE
NC score	0.050947 (rank : 478)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	156	Target Neighborhood Hits	1476	Shared Neighborhood Hits	79
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

BICD2_HUMAN
NC score	0.050940 (rank : 479)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	156	Target Neighborhood Hits	856	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

MYH4_HUMAN
NC score	0.050926 (rank : 480)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	156	Target Neighborhood Hits	1377	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

DLG5_HUMAN
NC score	0.050884 (rank : 481)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	156	Target Neighborhood Hits	1088	Shared Neighborhood Hits	70
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GLE1_MOUSE
NC score	0.050838 (rank : 482)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	156	Target Neighborhood Hits	504	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

CYTSA_MOUSE
NC score	0.050748 (rank : 483)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	156	Target Neighborhood Hits	1104	Shared Neighborhood Hits	65
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

MYH2_HUMAN
NC score	0.050711 (rank : 484)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	156	Target Neighborhood Hits	1491	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

LZTS1_HUMAN
NC score	0.050630 (rank : 485)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	156	Target Neighborhood Hits	532	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MYH1_HUMAN
NC score	0.050624 (rank : 486)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	156	Target Neighborhood Hits	1478	Shared Neighborhood Hits	76
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

HIP1R_HUMAN
NC score	0.050609 (rank : 487)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	156	Target Neighborhood Hits	809	Shared Neighborhood Hits	58
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

RUFY2_MOUSE
NC score	0.050579 (rank : 488)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	156	Target Neighborhood Hits	820	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

INVO_MOUSE
NC score	0.050570 (rank : 489)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	156	Target Neighborhood Hits	474	Shared Neighborhood Hits	50
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

PRC1_MOUSE
NC score	0.050568 (rank : 490)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	156	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

LIPA1_HUMAN
NC score	0.050539 (rank : 491)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	156	Target Neighborhood Hits	1294	Shared Neighborhood Hits	74
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MYH3_HUMAN
NC score	0.050449 (rank : 492)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	156	Target Neighborhood Hits	1660	Shared Neighborhood Hits	79
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

AL2SB_HUMAN
NC score	0.050436 (rank : 493)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	156	Target Neighborhood Hits	294	Shared Neighborhood Hits	42
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

RUSC1_HUMAN
NC score	0.050388 (rank : 494)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	156	Target Neighborhood Hits	226	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

TPM4_HUMAN
NC score	0.050373 (rank : 495)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	156	Target Neighborhood Hits	525	Shared Neighborhood Hits	52
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

SYNE1_HUMAN
NC score	0.050356 (rank : 496)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	156	Target Neighborhood Hits	1484	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

REN3B_HUMAN
NC score	0.050349 (rank : 497)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	156	Target Neighborhood Hits	412	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RABE2_HUMAN
NC score	0.050226 (rank : 498)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	156	Target Neighborhood Hits	545	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

LIPA2_MOUSE
NC score	0.050127 (rank : 499)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	156	Target Neighborhood Hits	1282	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

RENT2_HUMAN
NC score	0.050097 (rank : 500)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	156	Target Neighborhood Hits	618	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

CAR11_HUMAN
NC score	0.050034 (rank : 501)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	156	Target Neighborhood Hits	690	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CF055_MOUSE
NC score	0.048379 (rank : 502)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	156	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR26	Gene names
Domain Architecture
Description	Protein C6orf55 homolog.

BPAEA_HUMAN
NC score	0.048289 (rank : 503)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	156	Target Neighborhood Hits	1369	Shared Neighborhood Hits	65
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BAP29_MOUSE
NC score	0.045760 (rank : 504)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	156	Target Neighborhood Hits	285	Shared Neighborhood Hits	33
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

MYO7A_MOUSE
NC score	0.045520 (rank : 505)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	156	Target Neighborhood Hits	235	Shared Neighborhood Hits	26
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.044056 (rank : 506)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	156	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

WASIP_MOUSE
NC score	0.040369 (rank : 507)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	156	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

MDC1_HUMAN
NC score	0.037996 (rank : 508)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	156	Target Neighborhood Hits	1446	Shared Neighborhood Hits	44
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

WASIP_HUMAN
NC score	0.037796 (rank : 509)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	156	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BRD4_MOUSE
NC score	0.035785 (rank : 510)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	156	Target Neighborhood Hits	845	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

K0690_MOUSE
NC score	0.034496 (rank : 511)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	156	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

ANR21_HUMAN
NC score	0.030595 (rank : 512)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	156	Target Neighborhood Hits	864	Shared Neighborhood Hits	55
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ROCK2_HUMAN
NC score	0.030305 (rank : 513)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	156	Target Neighborhood Hits	2073	Shared Neighborhood Hits	71
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

NMNA2_HUMAN
NC score	0.029246 (rank : 514)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	156	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZQ4, O75067, Q5T1Q3, Q8WU99, Q96QW1	Gene names	NMNAT2, C1orf15, KIAA0479
Domain Architecture
Description	Nicotinamide mononucleotide adenylyltransferase 2 (EC 2.7.7.1) (NMN adenylyltransferase 2).

POT15_HUMAN
NC score	0.028993 (rank : 515)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	156	Target Neighborhood Hits	893	Shared Neighborhood Hits	49
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

FEZ1_MOUSE
NC score	0.028574 (rank : 516)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	156	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K0X8	Gene names	Fez1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

ANKS6_MOUSE
NC score	0.025282 (rank : 517)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	156	Target Neighborhood Hits	435	Shared Neighborhood Hits	13
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKS6_HUMAN
NC score	0.024555 (rank : 518)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	156	Target Neighborhood Hits	411	Shared Neighborhood Hits	10
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

PRAX_HUMAN
NC score	0.022979 (rank : 519)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	156	Target Neighborhood Hits	215	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
NC score	0.022645 (rank : 520)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	156	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

IF4G3_MOUSE
NC score	0.022265 (rank : 521)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	156	Target Neighborhood Hits	279	Shared Neighborhood Hits	16
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

NMNA2_MOUSE
NC score	0.021711 (rank : 522)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	156	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BNJ3	Gene names	Nmnat2, Kiaa0479
Domain Architecture
Description	Nicotinamide mononucleotide adenylyltransferase 2 (EC 2.7.7.1) (NMN adenylyltransferase 2).

PREP_HUMAN
NC score	0.021325 (rank : 523)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	156	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JRX3, O95204, Q2M2G6, Q4VBR1, Q5JRW7, Q7L5Z7, Q9BSI6, Q9BVJ5, Q9UPP8	Gene names	PITRM1, KIAA1104, MP1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (hPreP) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1).

PAPOG_MOUSE
NC score	0.021099 (rank : 524)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	156	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

LYN_HUMAN
NC score	0.018864 (rank : 525)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	156	Target Neighborhood Hits	1022	Shared Neighborhood Hits	53
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

HCK_MOUSE
NC score	0.018687 (rank : 526)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	156	Target Neighborhood Hits	1029	Shared Neighborhood Hits	55
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HCK_HUMAN
NC score	0.018640 (rank : 527)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	156	Target Neighborhood Hits	1035	Shared Neighborhood Hits	55
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

TFE3_HUMAN
NC score	0.018624 (rank : 528)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	156	Target Neighborhood Hits	190	Shared Neighborhood Hits	18
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

GFC1_HUMAN
NC score	0.017997 (rank : 529)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	156	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

M4K4_MOUSE
NC score	0.016873 (rank : 530)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	156	Target Neighborhood Hits	1560	Shared Neighborhood Hits	63
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.016509 (rank : 531)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	156	Target Neighborhood Hits	1589	Shared Neighborhood Hits	66
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

UBF1_HUMAN
NC score	0.015047 (rank : 532)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	156	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

EP400_HUMAN
NC score	0.009654 (rank : 533)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	156	Target Neighborhood Hits	556	Shared Neighborhood Hits	13
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

JHD2B_HUMAN
NC score	0.009046 (rank : 534)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	156	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

CAN1_HUMAN
NC score	0.007491 (rank : 535)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	156	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

K6PL_HUMAN
NC score	0.006308 (rank : 536)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	156	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P17858, Q96A64, Q96IH4, Q9BR91	Gene names	PFKL
Domain Architecture
Description	6-phosphofructokinase, liver type (EC 2.7.1.11) (Phosphofructokinase 1) (Phosphohexokinase) (Phosphofructo-1-kinase isozyme B) (PFK-B).

SCYL2_HUMAN
NC score	0.004981 (rank : 537)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	156	Target Neighborhood Hits	632	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

M3K13_HUMAN
NC score	-0.000806 (rank : 538)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	156	Target Neighborhood Hits	911	Shared Neighborhood Hits	10
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).