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Network neighborhood for query Sequence : SH3G2_MOUSE

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SH3G2_MOUSE
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SH3G2_HUMAN
θ value	0 (rank : 1)	NC score	0.994900 (rank : 2)
Query Neighborhood Hits	319	Target Neighborhood Hits	324	Shared Neighborhood Hits	296
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	319	Target Neighborhood Hits	319	Shared Neighborhood Hits	319
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G1_MOUSE
θ value	2.42647e-146 (rank : 3)	NC score	0.975493 (rank : 4)
Query Neighborhood Hits	319	Target Neighborhood Hits	291	Shared Neighborhood Hits	228
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G1_HUMAN
θ value	2.05413e-145 (rank : 4)	NC score	0.969228 (rank : 6)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	223
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G3_HUMAN
θ value	2.51683e-135 (rank : 5)	NC score	0.975661 (rank : 3)
Query Neighborhood Hits	319	Target Neighborhood Hits	222	Shared Neighborhood Hits	198
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G3_MOUSE
θ value	4.9119e-131 (rank : 6)	NC score	0.974074 (rank : 5)
Query Neighborhood Hits	319	Target Neighborhood Hits	236	Shared Neighborhood Hits	208
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SHLB1_HUMAN
θ value	5.23862e-24 (rank : 7)	NC score	0.671065 (rank : 8)
Query Neighborhood Hits	319	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SHLB1_MOUSE
θ value	5.23862e-24 (rank : 8)	NC score	0.674736 (rank : 7)
Query Neighborhood Hits	319	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SHLB2_HUMAN
θ value	6.62687e-19 (rank : 9)	NC score	0.622489 (rank : 16)
Query Neighborhood Hits	319	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	2.5182e-18 (rank : 10)	NC score	0.624066 (rank : 15)
Query Neighborhood Hits	319	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SH3K1_MOUSE
θ value	1.47974e-10 (rank : 11)	NC score	0.652639 (rank : 10)
Query Neighborhood Hits	319	Target Neighborhood Hits	332	Shared Neighborhood Hits	207
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SH3K1_HUMAN
θ value	1.25267e-09 (rank : 12)	NC score	0.652703 (rank : 9)
Query Neighborhood Hits	319	Target Neighborhood Hits	341	Shared Neighborhood Hits	208
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

GRB2_HUMAN
θ value	1.63604e-09 (rank : 13)	NC score	0.546331 (rank : 34)
Query Neighborhood Hits	319	Target Neighborhood Hits	310	Shared Neighborhood Hits	190
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	1.63604e-09 (rank : 14)	NC score	0.545634 (rank : 35)
Query Neighborhood Hits	319	Target Neighborhood Hits	312	Shared Neighborhood Hits	190
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

VINEX_HUMAN
θ value	1.06045e-08 (rank : 15)	NC score	0.630953 (rank : 13)
Query Neighborhood Hits	319	Target Neighborhood Hits	270	Shared Neighborhood Hits	193
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	3.08544e-08 (rank : 16)	NC score	0.630411 (rank : 14)
Query Neighborhood Hits	319	Target Neighborhood Hits	286	Shared Neighborhood Hits	190
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRBS1_HUMAN
θ value	4.0297e-08 (rank : 17)	NC score	0.614049 (rank : 18)
Query Neighborhood Hits	319	Target Neighborhood Hits	396	Shared Neighborhood Hits	199
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ABI2_HUMAN
θ value	5.26297e-08 (rank : 18)	NC score	0.589540 (rank : 27)
Query Neighborhood Hits	319	Target Neighborhood Hits	350	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	5.26297e-08 (rank : 19)	NC score	0.596337 (rank : 25)
Query Neighborhood Hits	319	Target Neighborhood Hits	266	Shared Neighborhood Hits	175
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

OSTF1_HUMAN
θ value	5.26297e-08 (rank : 20)	NC score	0.472181 (rank : 61)
Query Neighborhood Hits	319	Target Neighborhood Hits	466	Shared Neighborhood Hits	186
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

SRBS1_MOUSE
θ value	5.26297e-08 (rank : 21)	NC score	0.609712 (rank : 19)
Query Neighborhood Hits	319	Target Neighborhood Hits	409	Shared Neighborhood Hits	198
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CD2AP_HUMAN
θ value	6.87365e-08 (rank : 22)	NC score	0.636530 (rank : 12)
Query Neighborhood Hits	319	Target Neighborhood Hits	315	Shared Neighborhood Hits	199
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

HCLS1_HUMAN
θ value	6.87365e-08 (rank : 23)	NC score	0.607874 (rank : 21)
Query Neighborhood Hits	319	Target Neighborhood Hits	358	Shared Neighborhood Hits	164
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	8.97725e-08 (rank : 24)	NC score	0.609090 (rank : 20)
Query Neighborhood Hits	319	Target Neighborhood Hits	329	Shared Neighborhood Hits	168
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

ITSN1_HUMAN
θ value	1.17247e-07 (rank : 25)	NC score	0.403144 (rank : 84)
Query Neighborhood Hits	319	Target Neighborhood Hits	1757	Shared Neighborhood Hits	297
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NCF4_HUMAN
θ value	1.17247e-07 (rank : 26)	NC score	0.604371 (rank : 22)
Query Neighborhood Hits	319	Target Neighborhood Hits	161	Shared Neighborhood Hits	131
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

STAC_HUMAN
θ value	1.17247e-07 (rank : 27)	NC score	0.549070 (rank : 33)
Query Neighborhood Hits	319	Target Neighborhood Hits	276	Shared Neighborhood Hits	175
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CD2AP_MOUSE
θ value	1.53129e-07 (rank : 28)	NC score	0.641266 (rank : 11)
Query Neighborhood Hits	319	Target Neighborhood Hits	336	Shared Neighborhood Hits	201
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

MYO1F_HUMAN
θ value	1.53129e-07 (rank : 29)	NC score	0.276568 (rank : 119)
Query Neighborhood Hits	319	Target Neighborhood Hits	275	Shared Neighborhood Hits	196
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

OSTF1_MOUSE
θ value	1.53129e-07 (rank : 30)	NC score	0.458364 (rank : 65)
Query Neighborhood Hits	319	Target Neighborhood Hits	467	Shared Neighborhood Hits	186
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ITSN2_HUMAN
θ value	1.99992e-07 (rank : 31)	NC score	0.418087 (rank : 78)
Query Neighborhood Hits	319	Target Neighborhood Hits	1173	Shared Neighborhood Hits	270
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

NCF4_MOUSE
θ value	1.99992e-07 (rank : 32)	NC score	0.614934 (rank : 17)
Query Neighborhood Hits	319	Target Neighborhood Hits	177	Shared Neighborhood Hits	147
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SRC8_MOUSE
θ value	1.99992e-07 (rank : 33)	NC score	0.599383 (rank : 23)
Query Neighborhood Hits	319	Target Neighborhood Hits	292	Shared Neighborhood Hits	179
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

STAM2_MOUSE
θ value	2.61198e-07 (rank : 34)	NC score	0.553753 (rank : 31)
Query Neighborhood Hits	319	Target Neighborhood Hits	285	Shared Neighborhood Hits	186
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

ITSN1_MOUSE
θ value	3.41135e-07 (rank : 35)	NC score	0.403621 (rank : 83)
Query Neighborhood Hits	319	Target Neighborhood Hits	1669	Shared Neighborhood Hits	292
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ARHG7_HUMAN
θ value	4.45536e-07 (rank : 36)	NC score	0.501387 (rank : 51)
Query Neighborhood Hits	319	Target Neighborhood Hits	347	Shared Neighborhood Hits	195
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

MYO1E_HUMAN
θ value	4.45536e-07 (rank : 37)	NC score	0.266068 (rank : 125)
Query Neighborhood Hits	319	Target Neighborhood Hits	293	Shared Neighborhood Hits	193
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

STAM1_HUMAN
θ value	4.45536e-07 (rank : 38)	NC score	0.561116 (rank : 29)
Query Neighborhood Hits	319	Target Neighborhood Hits	271	Shared Neighborhood Hits	186
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ITSN2_MOUSE
θ value	5.81887e-07 (rank : 39)	NC score	0.397396 (rank : 87)
Query Neighborhood Hits	319	Target Neighborhood Hits	1371	Shared Neighborhood Hits	284
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

STAM1_MOUSE
θ value	5.81887e-07 (rank : 40)	NC score	0.557666 (rank : 30)
Query Neighborhood Hits	319	Target Neighborhood Hits	273	Shared Neighborhood Hits	182
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

MYO1F_MOUSE
θ value	7.59969e-07 (rank : 41)	NC score	0.273963 (rank : 120)
Query Neighborhood Hits	319	Target Neighborhood Hits	262	Shared Neighborhood Hits	195
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

DDEF1_MOUSE
θ value	9.92553e-07 (rank : 42)	NC score	0.304290 (rank : 112)
Query Neighborhood Hits	319	Target Neighborhood Hits	592	Shared Neighborhood Hits	154
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

M3K11_HUMAN
θ value	9.92553e-07 (rank : 43)	NC score	0.151634 (rank : 163)
Query Neighborhood Hits	319	Target Neighborhood Hits	1136	Shared Neighborhood Hits	177
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

GRAP2_HUMAN
θ value	1.29631e-06 (rank : 44)	NC score	0.527895 (rank : 40)
Query Neighborhood Hits	319	Target Neighborhood Hits	304	Shared Neighborhood Hits	186
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	1.29631e-06 (rank : 45)	NC score	0.535275 (rank : 36)
Query Neighborhood Hits	319	Target Neighborhood Hits	297	Shared Neighborhood Hits	186
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

SRC8_HUMAN
θ value	1.29631e-06 (rank : 46)	NC score	0.599302 (rank : 24)
Query Neighborhood Hits	319	Target Neighborhood Hits	269	Shared Neighborhood Hits	178
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

PACN1_HUMAN
θ value	1.69304e-06 (rank : 47)	NC score	0.506673 (rank : 48)
Query Neighborhood Hits	319	Target Neighborhood Hits	320	Shared Neighborhood Hits	186
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

ABI1_MOUSE
θ value	2.21117e-06 (rank : 48)	NC score	0.568965 (rank : 28)
Query Neighborhood Hits	319	Target Neighborhood Hits	246	Shared Neighborhood Hits	163
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ARHG6_HUMAN
θ value	2.21117e-06 (rank : 49)	NC score	0.482442 (rank : 59)
Query Neighborhood Hits	319	Target Neighborhood Hits	376	Shared Neighborhood Hits	202
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

PACN1_MOUSE
θ value	2.21117e-06 (rank : 50)	NC score	0.505206 (rank : 49)
Query Neighborhood Hits	319	Target Neighborhood Hits	283	Shared Neighborhood Hits	181
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

STAM2_HUMAN
θ value	2.21117e-06 (rank : 51)	NC score	0.528584 (rank : 38)
Query Neighborhood Hits	319	Target Neighborhood Hits	288	Shared Neighborhood Hits	186
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

DNMBP_HUMAN
θ value	2.88788e-06 (rank : 52)	NC score	0.500785 (rank : 52)
Query Neighborhood Hits	319	Target Neighborhood Hits	413	Shared Neighborhood Hits	196
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ABI1_HUMAN
θ value	3.77169e-06 (rank : 53)	NC score	0.552264 (rank : 32)
Query Neighborhood Hits	319	Target Neighborhood Hits	257	Shared Neighborhood Hits	163
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI3_HUMAN
θ value	3.77169e-06 (rank : 54)	NC score	0.523129 (rank : 42)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	137
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ARHG7_MOUSE
θ value	3.77169e-06 (rank : 55)	NC score	0.505162 (rank : 50)
Query Neighborhood Hits	319	Target Neighborhood Hits	396	Shared Neighborhood Hits	209
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

DNMBP_MOUSE
θ value	3.77169e-06 (rank : 56)	NC score	0.491126 (rank : 56)
Query Neighborhood Hits	319	Target Neighborhood Hits	435	Shared Neighborhood Hits	195
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ARHG6_MOUSE
θ value	6.43352e-06 (rank : 57)	NC score	0.489096 (rank : 58)
Query Neighborhood Hits	319	Target Neighborhood Hits	394	Shared Neighborhood Hits	202
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

AHI1_MOUSE
θ value	8.40245e-06 (rank : 58)	NC score	0.390928 (rank : 89)
Query Neighborhood Hits	319	Target Neighborhood Hits	496	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

CT032_HUMAN
θ value	8.40245e-06 (rank : 59)	NC score	0.473332 (rank : 60)
Query Neighborhood Hits	319	Target Neighborhood Hits	235	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

LASP1_MOUSE
θ value	1.09739e-05 (rank : 60)	NC score	0.492938 (rank : 55)
Query Neighborhood Hits	319	Target Neighborhood Hits	297	Shared Neighborhood Hits	148
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

SNX18_MOUSE
θ value	1.09739e-05 (rank : 61)	NC score	0.453148 (rank : 68)
Query Neighborhood Hits	319	Target Neighborhood Hits	198	Shared Neighborhood Hits	131
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

AHI1_HUMAN
θ value	1.43324e-05 (rank : 62)	NC score	0.382271 (rank : 94)
Query Neighborhood Hits	319	Target Neighborhood Hits	537	Shared Neighborhood Hits	179
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CASL_HUMAN
θ value	1.43324e-05 (rank : 63)	NC score	0.405509 (rank : 82)
Query Neighborhood Hits	319	Target Neighborhood Hits	259	Shared Neighborhood Hits	149
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	1.43324e-05 (rank : 64)	NC score	0.406190 (rank : 81)
Query Neighborhood Hits	319	Target Neighborhood Hits	225	Shared Neighborhood Hits	145
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

DBNL_HUMAN
θ value	1.43324e-05 (rank : 65)	NC score	0.534639 (rank : 37)
Query Neighborhood Hits	319	Target Neighborhood Hits	244	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	1.43324e-05 (rank : 66)	NC score	0.528445 (rank : 39)
Query Neighborhood Hits	319	Target Neighborhood Hits	306	Shared Neighborhood Hits	154
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

SNX18_HUMAN
θ value	1.43324e-05 (rank : 67)	NC score	0.445514 (rank : 72)
Query Neighborhood Hits	319	Target Neighborhood Hits	207	Shared Neighborhood Hits	132
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

VAV_MOUSE
θ value	1.43324e-05 (rank : 68)	NC score	0.420625 (rank : 77)
Query Neighborhood Hits	319	Target Neighborhood Hits	430	Shared Neighborhood Hits	190
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

GRAP_HUMAN
θ value	1.87187e-05 (rank : 69)	NC score	0.490032 (rank : 57)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	190
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	1.87187e-05 (rank : 70)	NC score	0.497463 (rank : 53)
Query Neighborhood Hits	319	Target Neighborhood Hits	309	Shared Neighborhood Hits	192
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

VAV_HUMAN
θ value	1.87187e-05 (rank : 71)	NC score	0.416786 (rank : 79)
Query Neighborhood Hits	319	Target Neighborhood Hits	452	Shared Neighborhood Hits	188
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ABI3_MOUSE
θ value	2.44474e-05 (rank : 72)	NC score	0.507493 (rank : 47)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

LASP1_HUMAN
θ value	2.44474e-05 (rank : 73)	NC score	0.493683 (rank : 54)
Query Neighborhood Hits	319	Target Neighborhood Hits	293	Shared Neighborhood Hits	149
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

PACN2_HUMAN
θ value	2.44474e-05 (rank : 74)	NC score	0.518556 (rank : 43)
Query Neighborhood Hits	319	Target Neighborhood Hits	339	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

NEBL_HUMAN
θ value	3.19293e-05 (rank : 75)	NC score	0.463409 (rank : 63)
Query Neighborhood Hits	319	Target Neighborhood Hits	457	Shared Neighborhood Hits	192
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

PACN2_MOUSE
θ value	4.1701e-05 (rank : 76)	NC score	0.511275 (rank : 45)
Query Neighborhood Hits	319	Target Neighborhood Hits	382	Shared Neighborhood Hits	199
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

STAC_MOUSE
θ value	4.1701e-05 (rank : 77)	NC score	0.524769 (rank : 41)
Query Neighborhood Hits	319	Target Neighborhood Hits	268	Shared Neighborhood Hits	170
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

RIMB2_HUMAN
θ value	9.29e-05 (rank : 78)	NC score	0.387226 (rank : 91)
Query Neighborhood Hits	319	Target Neighborhood Hits	263	Shared Neighborhood Hits	126
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

NEBU_HUMAN
θ value	0.000121331 (rank : 79)	NC score	0.378476 (rank : 97)
Query Neighborhood Hits	319	Target Neighborhood Hits	420	Shared Neighborhood Hits	171
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

RIMB2_MOUSE
θ value	0.000121331 (rank : 80)	NC score	0.385642 (rank : 92)
Query Neighborhood Hits	319	Target Neighborhood Hits	246	Shared Neighborhood Hits	125
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

DDEF2_HUMAN
θ value	0.000158464 (rank : 81)	NC score	0.268206 (rank : 123)
Query Neighborhood Hits	319	Target Neighborhood Hits	599	Shared Neighborhood Hits	159
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

M3KL4_HUMAN
θ value	0.000158464 (rank : 82)	NC score	0.162487 (rank : 157)
Query Neighborhood Hits	319	Target Neighborhood Hits	1087	Shared Neighborhood Hits	194
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

SPTA2_HUMAN
θ value	0.00020696 (rank : 83)	NC score	0.260392 (rank : 128)
Query Neighborhood Hits	319	Target Neighborhood Hits	888	Shared Neighborhood Hits	234
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

3BP1_HUMAN
θ value	0.000270298 (rank : 84)	NC score	0.113190 (rank : 204)
Query Neighborhood Hits	319	Target Neighborhood Hits	376	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BCAR1_HUMAN
θ value	0.000270298 (rank : 85)	NC score	0.397953 (rank : 86)
Query Neighborhood Hits	319	Target Neighborhood Hits	554	Shared Neighborhood Hits	166
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CSKP_HUMAN
θ value	0.000270298 (rank : 86)	NC score	0.074026 (rank : 292)
Query Neighborhood Hits	319	Target Neighborhood Hits	1022	Shared Neighborhood Hits	117
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

DDEF2_MOUSE
θ value	0.000270298 (rank : 87)	NC score	0.272267 (rank : 121)
Query Neighborhood Hits	319	Target Neighborhood Hits	625	Shared Neighborhood Hits	159
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

NCF2_HUMAN
θ value	0.000270298 (rank : 88)	NC score	0.593526 (rank : 26)
Query Neighborhood Hits	319	Target Neighborhood Hits	229	Shared Neighborhood Hits	164
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

CSKP_MOUSE
θ value	0.00035302 (rank : 89)	NC score	0.073614 (rank : 294)
Query Neighborhood Hits	319	Target Neighborhood Hits	1027	Shared Neighborhood Hits	124
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

RIMB1_HUMAN
θ value	0.00035302 (rank : 90)	NC score	0.253860 (rank : 130)
Query Neighborhood Hits	319	Target Neighborhood Hits	1479	Shared Neighborhood Hits	226
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ASPP2_HUMAN
θ value	0.000461057 (rank : 91)	NC score	0.250186 (rank : 131)
Query Neighborhood Hits	319	Target Neighborhood Hits	1156	Shared Neighborhood Hits	206
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CRKL_HUMAN
θ value	0.000602161 (rank : 92)	NC score	0.453462 (rank : 66)
Query Neighborhood Hits	319	Target Neighborhood Hits	313	Shared Neighborhood Hits	182
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

LCK_HUMAN
θ value	0.000602161 (rank : 93)	NC score	0.108895 (rank : 217)
Query Neighborhood Hits	319	Target Neighborhood Hits	987	Shared Neighborhood Hits	117
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	0.000602161 (rank : 94)	NC score	0.108298 (rank : 218)
Query Neighborhood Hits	319	Target Neighborhood Hits	981	Shared Neighborhood Hits	116
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

SRC_HUMAN
θ value	0.000602161 (rank : 95)	NC score	0.146587 (rank : 168)
Query Neighborhood Hits	319	Target Neighborhood Hits	1058	Shared Neighborhood Hits	178
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

TXK_MOUSE
θ value	0.000602161 (rank : 96)	NC score	0.109523 (rank : 215)
Query Neighborhood Hits	319	Target Neighborhood Hits	980	Shared Neighborhood Hits	138
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

BCAR1_MOUSE
θ value	0.000786445 (rank : 97)	NC score	0.401984 (rank : 85)
Query Neighborhood Hits	319	Target Neighborhood Hits	438	Shared Neighborhood Hits	161
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

FYN_HUMAN
θ value	0.000786445 (rank : 98)	NC score	0.149734 (rank : 165)
Query Neighborhood Hits	319	Target Neighborhood Hits	1078	Shared Neighborhood Hits	181
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	0.000786445 (rank : 99)	NC score	0.152425 (rank : 162)
Query Neighborhood Hits	319	Target Neighborhood Hits	1073	Shared Neighborhood Hits	181
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

RHG26_HUMAN
θ value	0.000786445 (rank : 100)	NC score	0.292269 (rank : 114)
Query Neighborhood Hits	319	Target Neighborhood Hits	281	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

YES_MOUSE
θ value	0.000786445 (rank : 101)	NC score	0.147152 (rank : 166)
Query Neighborhood Hits	319	Target Neighborhood Hits	1052	Shared Neighborhood Hits	176
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

CRKL_MOUSE
θ value	0.00102713 (rank : 102)	NC score	0.447750 (rank : 71)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	181
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

ASPP1_MOUSE
θ value	0.00134147 (rank : 103)	NC score	0.282586 (rank : 116)
Query Neighborhood Hits	319	Target Neighborhood Hits	1244	Shared Neighborhood Hits	215
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CRK_HUMAN
θ value	0.00134147 (rank : 104)	NC score	0.444709 (rank : 73)
Query Neighborhood Hits	319	Target Neighborhood Hits	308	Shared Neighborhood Hits	186
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	0.00134147 (rank : 105)	NC score	0.450736 (rank : 69)
Query Neighborhood Hits	319	Target Neighborhood Hits	314	Shared Neighborhood Hits	186
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

EFS_HUMAN
θ value	0.00134147 (rank : 106)	NC score	0.388179 (rank : 90)
Query Neighborhood Hits	319	Target Neighborhood Hits	348	Shared Neighborhood Hits	149
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	0.00134147 (rank : 107)	NC score	0.395338 (rank : 88)
Query Neighborhood Hits	319	Target Neighborhood Hits	389	Shared Neighborhood Hits	154
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

PPIP1_MOUSE
θ value	0.00134147 (rank : 108)	NC score	0.512934 (rank : 44)
Query Neighborhood Hits	319	Target Neighborhood Hits	377	Shared Neighborhood Hits	208
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

RIMB1_MOUSE
θ value	0.00134147 (rank : 109)	NC score	0.240937 (rank : 134)
Query Neighborhood Hits	319	Target Neighborhood Hits	1376	Shared Neighborhood Hits	244
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SNX9_HUMAN
θ value	0.00134147 (rank : 110)	NC score	0.328244 (rank : 105)
Query Neighborhood Hits	319	Target Neighborhood Hits	148	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

ARHG4_HUMAN
θ value	0.00175202 (rank : 111)	NC score	0.350528 (rank : 100)
Query Neighborhood Hits	319	Target Neighborhood Hits	242	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

PPIP1_HUMAN
θ value	0.00175202 (rank : 112)	NC score	0.509144 (rank : 46)
Query Neighborhood Hits	319	Target Neighborhood Hits	389	Shared Neighborhood Hits	208
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SKI_HUMAN
θ value	0.00175202 (rank : 113)	NC score	0.111859 (rank : 210)
Query Neighborhood Hits	319	Target Neighborhood Hits	423	Shared Neighborhood Hits	68
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

VAV2_HUMAN
θ value	0.00175202 (rank : 114)	NC score	0.380486 (rank : 95)
Query Neighborhood Hits	319	Target Neighborhood Hits	453	Shared Neighborhood Hits	176
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	0.00175202 (rank : 115)	NC score	0.382464 (rank : 93)
Query Neighborhood Hits	319	Target Neighborhood Hits	456	Shared Neighborhood Hits	176
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

PACN3_HUMAN
θ value	0.00228821 (rank : 116)	NC score	0.461963 (rank : 64)
Query Neighborhood Hits	319	Target Neighborhood Hits	385	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	0.00228821 (rank : 117)	NC score	0.463926 (rank : 62)
Query Neighborhood Hits	319	Target Neighborhood Hits	380	Shared Neighborhood Hits	197
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

SPTA1_MOUSE
θ value	0.00228821 (rank : 118)	NC score	0.249519 (rank : 132)
Query Neighborhood Hits	319	Target Neighborhood Hits	675	Shared Neighborhood Hits	202
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ARHG5_HUMAN
θ value	0.00298849 (rank : 119)	NC score	0.230762 (rank : 138)
Query Neighborhood Hits	319	Target Neighborhood Hits	172	Shared Neighborhood Hits	89
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

YES_HUMAN
θ value	0.00298849 (rank : 120)	NC score	0.144810 (rank : 172)
Query Neighborhood Hits	319	Target Neighborhood Hits	1059	Shared Neighborhood Hits	174
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

IASPP_HUMAN
θ value	0.00390308 (rank : 121)	NC score	0.292007 (rank : 115)
Query Neighborhood Hits	319	Target Neighborhood Hits	688	Shared Neighborhood Hits	153
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SNX9_MOUSE
θ value	0.00390308 (rank : 122)	NC score	0.307592 (rank : 111)
Query Neighborhood Hits	319	Target Neighborhood Hits	141	Shared Neighborhood Hits	92
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

IASPP_MOUSE
θ value	0.00509761 (rank : 123)	NC score	0.266446 (rank : 124)
Query Neighborhood Hits	319	Target Neighborhood Hits	1024	Shared Neighborhood Hits	161
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

M3K9_HUMAN
θ value	0.00509761 (rank : 124)	NC score	0.136337 (rank : 179)
Query Neighborhood Hits	319	Target Neighborhood Hits	1123	Shared Neighborhood Hits	183
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NCK2_HUMAN
θ value	0.00509761 (rank : 125)	NC score	0.453238 (rank : 67)
Query Neighborhood Hits	319	Target Neighborhood Hits	310	Shared Neighborhood Hits	183
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

SKI_MOUSE
θ value	0.00509761 (rank : 126)	NC score	0.109593 (rank : 214)
Query Neighborhood Hits	319	Target Neighborhood Hits	423	Shared Neighborhood Hits	66
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

ARHG9_HUMAN
θ value	0.00665767 (rank : 127)	NC score	0.331576 (rank : 103)
Query Neighborhood Hits	319	Target Neighborhood Hits	235	Shared Neighborhood Hits	154
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	0.00665767 (rank : 128)	NC score	0.331393 (rank : 104)
Query Neighborhood Hits	319	Target Neighborhood Hits	234	Shared Neighborhood Hits	154
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ASPP1_HUMAN
θ value	0.00665767 (rank : 129)	NC score	0.279525 (rank : 117)
Query Neighborhood Hits	319	Target Neighborhood Hits	956	Shared Neighborhood Hits	205
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PLCB3_MOUSE
θ value	0.00869519 (rank : 130)	NC score	0.065052 (rank : 373)
Query Neighborhood Hits	319	Target Neighborhood Hits	344	Shared Neighborhood Hits	56
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

SHAN2_MOUSE
θ value	0.0113563 (rank : 131)	NC score	0.212386 (rank : 142)
Query Neighborhood Hits	319	Target Neighborhood Hits	446	Shared Neighborhood Hits	107
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SPTA1_HUMAN
θ value	0.0113563 (rank : 132)	NC score	0.238389 (rank : 137)
Query Neighborhood Hits	319	Target Neighborhood Hits	748	Shared Neighborhood Hits	222
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

STAC3_HUMAN
θ value	0.0113563 (rank : 133)	NC score	0.433539 (rank : 75)
Query Neighborhood Hits	319	Target Neighborhood Hits	228	Shared Neighborhood Hits	141
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	0.0148317 (rank : 134)	NC score	0.437085 (rank : 74)
Query Neighborhood Hits	319	Target Neighborhood Hits	232	Shared Neighborhood Hits	143
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

VAV3_MOUSE
θ value	0.0148317 (rank : 135)	NC score	0.344822 (rank : 102)
Query Neighborhood Hits	319	Target Neighborhood Hits	404	Shared Neighborhood Hits	171
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

FGR_HUMAN
θ value	0.0193708 (rank : 136)	NC score	0.145863 (rank : 169)
Query Neighborhood Hits	319	Target Neighborhood Hits	1067	Shared Neighborhood Hits	174
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

CTBL1_MOUSE
θ value	0.0330416 (rank : 137)	NC score	0.073425 (rank : 295)
Query Neighborhood Hits	319	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CWL8, Q3UL41, Q80X64, Q8VHE3	Gene names	Ctnnbl1
Domain Architecture	No domain graphic available
Description	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP).

CTRO_MOUSE
θ value	0.0330416 (rank : 138)	NC score	0.053320 (rank : 533)
Query Neighborhood Hits	319	Target Neighborhood Hits	2344	Shared Neighborhood Hits	153
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ERC2_MOUSE
θ value	0.0330416 (rank : 139)	NC score	0.078191 (rank : 270)
Query Neighborhood Hits	319	Target Neighborhood Hits	1166	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

GLE1_HUMAN
θ value	0.0330416 (rank : 140)	NC score	0.117328 (rank : 198)
Query Neighborhood Hits	319	Target Neighborhood Hits	445	Shared Neighborhood Hits	75
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

M3K10_HUMAN
θ value	0.0330416 (rank : 141)	NC score	0.124941 (rank : 189)
Query Neighborhood Hits	319	Target Neighborhood Hits	1071	Shared Neighborhood Hits	166
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

VAV3_HUMAN
θ value	0.0330416 (rank : 142)	NC score	0.349765 (rank : 101)
Query Neighborhood Hits	319	Target Neighborhood Hits	398	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

EM55_HUMAN
θ value	0.0431538 (rank : 143)	NC score	0.179685 (rank : 149)
Query Neighborhood Hits	319	Target Neighborhood Hits	228	Shared Neighborhood Hits	96
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	0.0431538 (rank : 144)	NC score	0.176468 (rank : 150)
Query Neighborhood Hits	319	Target Neighborhood Hits	221	Shared Neighborhood Hits	92
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NCK1_HUMAN
θ value	0.0431538 (rank : 145)	NC score	0.449439 (rank : 70)
Query Neighborhood Hits	319	Target Neighborhood Hits	312	Shared Neighborhood Hits	186
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

PEX13_HUMAN
θ value	0.0431538 (rank : 146)	NC score	0.356200 (rank : 98)
Query Neighborhood Hits	319	Target Neighborhood Hits	128	Shared Neighborhood Hits	106
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PLCG1_MOUSE
θ value	0.0431538 (rank : 147)	NC score	0.320665 (rank : 107)
Query Neighborhood Hits	319	Target Neighborhood Hits	314	Shared Neighborhood Hits	153
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

SRC_MOUSE
θ value	0.0431538 (rank : 148)	NC score	0.121361 (rank : 193)
Query Neighborhood Hits	319	Target Neighborhood Hits	1033	Shared Neighborhood Hits	157
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRGP2_HUMAN
θ value	0.0431538 (rank : 149)	NC score	0.258030 (rank : 129)
Query Neighborhood Hits	319	Target Neighborhood Hits	331	Shared Neighborhood Hits	165
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	0.0431538 (rank : 150)	NC score	0.261909 (rank : 127)
Query Neighborhood Hits	319	Target Neighborhood Hits	324	Shared Neighborhood Hits	170
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CENPQ_HUMAN
θ value	0.0563607 (rank : 151)	NC score	0.095257 (rank : 239)
Query Neighborhood Hits	319	Target Neighborhood Hits	131	Shared Neighborhood Hits	27
SwissProt Accessions	Q7L2Z9, Q6IN61, Q9NVS5	Gene names	CENPQ, C6orf139
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

ERC2_HUMAN
θ value	0.0563607 (rank : 152)	NC score	0.075843 (rank : 283)
Query Neighborhood Hits	319	Target Neighborhood Hits	1156	Shared Neighborhood Hits	112
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

BPTF_HUMAN
θ value	0.0736092 (rank : 153)	NC score	0.041268 (rank : 599)
Query Neighborhood Hits	319	Target Neighborhood Hits	786	Shared Neighborhood Hits	45
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

NPHP1_MOUSE
θ value	0.0736092 (rank : 154)	NC score	0.378934 (rank : 96)
Query Neighborhood Hits	319	Target Neighborhood Hits	267	Shared Neighborhood Hits	184
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

RUSC1_HUMAN
θ value	0.0736092 (rank : 155)	NC score	0.328121 (rank : 106)
Query Neighborhood Hits	319	Target Neighborhood Hits	226	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SHAN1_HUMAN
θ value	0.0736092 (rank : 156)	NC score	0.146861 (rank : 167)
Query Neighborhood Hits	319	Target Neighborhood Hits	1041	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SLY_MOUSE
θ value	0.0736092 (rank : 157)	NC score	0.174163 (rank : 151)
Query Neighborhood Hits	319	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

CTBL1_HUMAN
θ value	0.0961366 (rank : 158)	NC score	0.068742 (rank : 336)
Query Neighborhood Hits	319	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYA6, Q53HI8, Q5JWZ2, Q5JWZ3, Q5JWZ7, Q5JWZ8, Q8N454, Q8NCL2, Q8TBD6, Q96KD2, Q9H7A5, Q9NQF9, Q9NTX0, Q9Y3M7	Gene names	CTNNBL1, C20orf33
Domain Architecture
Description	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19).

FGR_MOUSE
θ value	0.0961366 (rank : 159)	NC score	0.139213 (rank : 177)
Query Neighborhood Hits	319	Target Neighborhood Hits	1069	Shared Neighborhood Hits	173
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

MY18A_MOUSE
θ value	0.0961366 (rank : 160)	NC score	0.084082 (rank : 263)
Query Neighborhood Hits	319	Target Neighborhood Hits	1989	Shared Neighborhood Hits	142
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SLY_HUMAN
θ value	0.0961366 (rank : 161)	NC score	0.155222 (rank : 161)
Query Neighborhood Hits	319	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SRGP1_HUMAN
θ value	0.0961366 (rank : 162)	NC score	0.241507 (rank : 133)
Query Neighborhood Hits	319	Target Neighborhood Hits	390	Shared Neighborhood Hits	164
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

AZI1_MOUSE
θ value	0.125558 (rank : 163)	NC score	0.070795 (rank : 318)
Query Neighborhood Hits	319	Target Neighborhood Hits	990	Shared Neighborhood Hits	105
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

GCC2_HUMAN
θ value	0.125558 (rank : 164)	NC score	0.076015 (rank : 282)
Query Neighborhood Hits	319	Target Neighborhood Hits	1558	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

PEX13_MOUSE
θ value	0.125558 (rank : 165)	NC score	0.352756 (rank : 99)
Query Neighborhood Hits	319	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

RBP24_HUMAN
θ value	0.125558 (rank : 166)	NC score	0.076077 (rank : 281)
Query Neighborhood Hits	319	Target Neighborhood Hits	1559	Shared Neighborhood Hits	130
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RUSC1_MOUSE
θ value	0.125558 (rank : 167)	NC score	0.308993 (rank : 110)
Query Neighborhood Hits	319	Target Neighborhood Hits	206	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

ARHG4_MOUSE
θ value	0.163984 (rank : 168)	NC score	0.278019 (rank : 118)
Query Neighborhood Hits	319	Target Neighborhood Hits	185	Shared Neighborhood Hits	113
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

BTK_HUMAN
θ value	0.163984 (rank : 169)	NC score	0.124302 (rank : 190)
Query Neighborhood Hits	319	Target Neighborhood Hits	1026	Shared Neighborhood Hits	171
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

FNBP2_HUMAN
θ value	0.163984 (rank : 170)	NC score	0.240441 (rank : 135)
Query Neighborhood Hits	319	Target Neighborhood Hits	432	Shared Neighborhood Hits	174
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GLE1_MOUSE
θ value	0.163984 (rank : 171)	NC score	0.096404 (rank : 235)
Query Neighborhood Hits	319	Target Neighborhood Hits	504	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

PLCG1_HUMAN
θ value	0.163984 (rank : 172)	NC score	0.301756 (rank : 113)
Query Neighborhood Hits	319	Target Neighborhood Hits	293	Shared Neighborhood Hits	147
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

AMOL1_HUMAN
θ value	0.21417 (rank : 173)	NC score	0.060428 (rank : 422)
Query Neighborhood Hits	319	Target Neighborhood Hits	435	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

ES8L3_HUMAN
θ value	0.21417 (rank : 174)	NC score	0.239469 (rank : 136)
Query Neighborhood Hits	319	Target Neighborhood Hits	206	Shared Neighborhood Hits	119
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

M4K4_MOUSE
θ value	0.21417 (rank : 175)	NC score	0.038932 (rank : 602)
Query Neighborhood Hits	319	Target Neighborhood Hits	1560	Shared Neighborhood Hits	107
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

AMOL1_MOUSE
θ value	0.279714 (rank : 176)	NC score	0.056823 (rank : 474)
Query Neighborhood Hits	319	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

MYH2_HUMAN
θ value	0.279714 (rank : 177)	NC score	0.073415 (rank : 296)
Query Neighborhood Hits	319	Target Neighborhood Hits	1491	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

NEST_HUMAN
θ value	0.279714 (rank : 178)	NC score	0.057863 (rank : 459)
Query Neighborhood Hits	319	Target Neighborhood Hits	1305	Shared Neighborhood Hits	99
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PLCB3_HUMAN
θ value	0.279714 (rank : 179)	NC score	0.070786 (rank : 319)
Query Neighborhood Hits	319	Target Neighborhood Hits	445	Shared Neighborhood Hits	74
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

RHG04_HUMAN
θ value	0.279714 (rank : 180)	NC score	0.271921 (rank : 122)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	165
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

HOOK1_HUMAN
θ value	0.365318 (rank : 181)	NC score	0.056679 (rank : 478)
Query Neighborhood Hits	319	Target Neighborhood Hits	942	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MY18A_HUMAN
θ value	0.365318 (rank : 182)	NC score	0.083304 (rank : 264)
Query Neighborhood Hits	319	Target Neighborhood Hits	1929	Shared Neighborhood Hits	145
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH4_MOUSE
θ value	0.365318 (rank : 183)	NC score	0.072806 (rank : 298)
Query Neighborhood Hits	319	Target Neighborhood Hits	1476	Shared Neighborhood Hits	127
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

NCF1_HUMAN
θ value	0.365318 (rank : 184)	NC score	0.422812 (rank : 76)
Query Neighborhood Hits	319	Target Neighborhood Hits	198	Shared Neighborhood Hits	149
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

PLCG2_HUMAN
θ value	0.365318 (rank : 185)	NC score	0.311121 (rank : 108)
Query Neighborhood Hits	319	Target Neighborhood Hits	280	Shared Neighborhood Hits	149
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

RAD50_MOUSE
θ value	0.365318 (rank : 186)	NC score	0.072523 (rank : 299)
Query Neighborhood Hits	319	Target Neighborhood Hits	1366	Shared Neighborhood Hits	120
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

STS2_HUMAN
θ value	0.365318 (rank : 187)	NC score	0.205371 (rank : 143)
Query Neighborhood Hits	319	Target Neighborhood Hits	108	Shared Neighborhood Hits	81
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

TXK_HUMAN
θ value	0.365318 (rank : 188)	NC score	0.092274 (rank : 244)
Query Neighborhood Hits	319	Target Neighborhood Hits	971	Shared Neighborhood Hits	121
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

GOGA5_MOUSE
θ value	0.47712 (rank : 189)	NC score	0.069002 (rank : 330)
Query Neighborhood Hits	319	Target Neighborhood Hits	1434	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

NCOR2_HUMAN
θ value	0.47712 (rank : 190)	NC score	0.045486 (rank : 595)
Query Neighborhood Hits	319	Target Neighborhood Hits	870	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PCNT_MOUSE
θ value	0.47712 (rank : 191)	NC score	0.065603 (rank : 367)
Query Neighborhood Hits	319	Target Neighborhood Hits	1207	Shared Neighborhood Hits	109
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

TCGAP_HUMAN
θ value	0.47712 (rank : 192)	NC score	0.169524 (rank : 154)
Query Neighborhood Hits	319	Target Neighborhood Hits	872	Shared Neighborhood Hits	130
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	0.47712 (rank : 193)	NC score	0.189029 (rank : 148)
Query Neighborhood Hits	319	Target Neighborhood Hits	409	Shared Neighborhood Hits	124
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BTK_MOUSE
θ value	0.62314 (rank : 194)	NC score	0.117108 (rank : 200)
Query Neighborhood Hits	319	Target Neighborhood Hits	1017	Shared Neighborhood Hits	162
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CCHCR_HUMAN
θ value	0.62314 (rank : 195)	NC score	0.067145 (rank : 347)
Query Neighborhood Hits	319	Target Neighborhood Hits	717	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

DAAM2_HUMAN
θ value	0.62314 (rank : 196)	NC score	0.051532 (rank : 562)
Query Neighborhood Hits	319	Target Neighborhood Hits	350	Shared Neighborhood Hits	60
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ES8L3_MOUSE
θ value	0.62314 (rank : 197)	NC score	0.266052 (rank : 126)
Query Neighborhood Hits	319	Target Neighborhood Hits	168	Shared Neighborhood Hits	130
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

MPP2_MOUSE
θ value	0.62314 (rank : 198)	NC score	0.114174 (rank : 201)
Query Neighborhood Hits	319	Target Neighborhood Hits	189	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

OPHN1_HUMAN
θ value	0.62314 (rank : 199)	NC score	0.064980 (rank : 375)
Query Neighborhood Hits	319	Target Neighborhood Hits	161	Shared Neighborhood Hits	27
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

DJC17_HUMAN
θ value	0.813845 (rank : 200)	NC score	0.034442 (rank : 603)
Query Neighborhood Hits	319	Target Neighborhood Hits	335	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NVM6	Gene names	DNAJC17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

EEA1_MOUSE
θ value	0.813845 (rank : 201)	NC score	0.067824 (rank : 344)
Query Neighborhood Hits	319	Target Neighborhood Hits	1637	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EP15_MOUSE
θ value	0.813845 (rank : 202)	NC score	0.074435 (rank : 288)
Query Neighborhood Hits	319	Target Neighborhood Hits	820	Shared Neighborhood Hits	81
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ES8L2_MOUSE
θ value	0.813845 (rank : 203)	NC score	0.194837 (rank : 145)
Query Neighborhood Hits	319	Target Neighborhood Hits	169	Shared Neighborhood Hits	116
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

FYV1_MOUSE
θ value	0.813845 (rank : 204)	NC score	0.030474 (rank : 610)
Query Neighborhood Hits	319	Target Neighborhood Hits	191	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

NCOR2_MOUSE
θ value	0.813845 (rank : 205)	NC score	0.043564 (rank : 598)
Query Neighborhood Hits	319	Target Neighborhood Hits	790	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

TRHY_HUMAN
θ value	0.813845 (rank : 206)	NC score	0.068144 (rank : 342)
Query Neighborhood Hits	319	Target Neighborhood Hits	1385	Shared Neighborhood Hits	110
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

XE7_HUMAN
θ value	0.813845 (rank : 207)	NC score	0.067003 (rank : 349)
Query Neighborhood Hits	319	Target Neighborhood Hits	738	Shared Neighborhood Hits	78
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

DAAM2_MOUSE
θ value	1.06291 (rank : 208)	NC score	0.040265 (rank : 600)
Query Neighborhood Hits	319	Target Neighborhood Hits	371	Shared Neighborhood Hits	50
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ES8L2_HUMAN
θ value	1.06291 (rank : 209)	NC score	0.196603 (rank : 144)
Query Neighborhood Hits	319	Target Neighborhood Hits	193	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

MATK_MOUSE
θ value	1.06291 (rank : 210)	NC score	0.066219 (rank : 355)
Query Neighborhood Hits	319	Target Neighborhood Hits	952	Shared Neighborhood Hits	79
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

TPM3_HUMAN
θ value	1.06291 (rank : 211)	NC score	0.054009 (rank : 523)
Query Neighborhood Hits	319	Target Neighborhood Hits	689	Shared Neighborhood Hits	78
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TPM3_MOUSE
θ value	1.06291 (rank : 212)	NC score	0.053228 (rank : 536)
Query Neighborhood Hits	319	Target Neighborhood Hits	676	Shared Neighborhood Hits	78
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

ANM2_HUMAN
θ value	1.38821 (rank : 213)	NC score	0.229283 (rank : 139)
Query Neighborhood Hits	319	Target Neighborhood Hits	175	Shared Neighborhood Hits	141
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

EP15_HUMAN
θ value	1.38821 (rank : 214)	NC score	0.071525 (rank : 311)
Query Neighborhood Hits	319	Target Neighborhood Hits	1021	Shared Neighborhood Hits	92
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

HCK_MOUSE
θ value	1.38821 (rank : 215)	NC score	0.121520 (rank : 192)
Query Neighborhood Hits	319	Target Neighborhood Hits	1029	Shared Neighborhood Hits	163
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

JIP1_HUMAN
θ value	1.38821 (rank : 216)	NC score	0.111839 (rank : 211)
Query Neighborhood Hits	319	Target Neighborhood Hits	271	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
θ value	1.38821 (rank : 217)	NC score	0.111686 (rank : 212)
Query Neighborhood Hits	319	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MPP2_HUMAN
θ value	1.38821 (rank : 218)	NC score	0.113963 (rank : 202)
Query Neighborhood Hits	319	Target Neighborhood Hits	173	Shared Neighborhood Hits	68
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MYH1_MOUSE
θ value	1.38821 (rank : 219)	NC score	0.073099 (rank : 297)
Query Neighborhood Hits	319	Target Neighborhood Hits	1461	Shared Neighborhood Hits	130
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

PININ_HUMAN
θ value	1.38821 (rank : 220)	NC score	0.051237 (rank : 567)
Query Neighborhood Hits	319	Target Neighborhood Hits	753	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

RUSC2_HUMAN
θ value	1.38821 (rank : 221)	NC score	0.130545 (rank : 183)
Query Neighborhood Hits	319	Target Neighborhood Hits	205	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SP100_HUMAN
θ value	1.38821 (rank : 222)	NC score	0.015551 (rank : 616)
Query Neighborhood Hits	319	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

TEC_MOUSE
θ value	1.38821 (rank : 223)	NC score	0.089155 (rank : 251)
Query Neighborhood Hits	319	Target Neighborhood Hits	1006	Shared Neighborhood Hits	133
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

CCHCR_MOUSE
θ value	1.81305 (rank : 224)	NC score	0.064739 (rank : 378)
Query Neighborhood Hits	319	Target Neighborhood Hits	932	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CROCC_HUMAN
θ value	1.81305 (rank : 225)	NC score	0.057830 (rank : 461)
Query Neighborhood Hits	319	Target Neighborhood Hits	1409	Shared Neighborhood Hits	117
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ENAH_HUMAN
θ value	1.81305 (rank : 226)	NC score	0.054383 (rank : 519)
Query Neighborhood Hits	319	Target Neighborhood Hits	784	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FYV1_HUMAN
θ value	1.81305 (rank : 227)	NC score	0.027734 (rank : 612)
Query Neighborhood Hits	319	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

HCK_HUMAN
θ value	1.81305 (rank : 228)	NC score	0.119984 (rank : 195)
Query Neighborhood Hits	319	Target Neighborhood Hits	1035	Shared Neighborhood Hits	164
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

LIPA3_HUMAN
θ value	1.81305 (rank : 229)	NC score	0.052711 (rank : 544)
Query Neighborhood Hits	319	Target Neighborhood Hits	828	Shared Neighborhood Hits	91
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MPP5_HUMAN
θ value	1.81305 (rank : 230)	NC score	0.113782 (rank : 203)
Query Neighborhood Hits	319	Target Neighborhood Hits	231	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	1.81305 (rank : 231)	NC score	0.113067 (rank : 206)
Query Neighborhood Hits	319	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MYH13_HUMAN
θ value	1.81305 (rank : 232)	NC score	0.071314 (rank : 315)
Query Neighborhood Hits	319	Target Neighborhood Hits	1504	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

NCF1_MOUSE
θ value	1.81305 (rank : 233)	NC score	0.411250 (rank : 80)
Query Neighborhood Hits	319	Target Neighborhood Hits	198	Shared Neighborhood Hits	162
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

SYNE1_HUMAN
θ value	1.81305 (rank : 234)	NC score	0.059142 (rank : 437)
Query Neighborhood Hits	319	Target Neighborhood Hits	1484	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

BAIP2_HUMAN
θ value	2.36792 (rank : 235)	NC score	0.137374 (rank : 178)
Query Neighborhood Hits	319	Target Neighborhood Hits	192	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	2.36792 (rank : 236)	NC score	0.139590 (rank : 176)
Query Neighborhood Hits	319	Target Neighborhood Hits	185	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

EEA1_HUMAN
θ value	2.36792 (rank : 237)	NC score	0.069456 (rank : 326)
Query Neighborhood Hits	319	Target Neighborhood Hits	1796	Shared Neighborhood Hits	132
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EPS8_HUMAN
θ value	2.36792 (rank : 238)	NC score	0.193490 (rank : 146)
Query Neighborhood Hits	319	Target Neighborhood Hits	151	Shared Neighborhood Hits	100
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
θ value	2.36792 (rank : 239)	NC score	0.189677 (rank : 147)
Query Neighborhood Hits	319	Target Neighborhood Hits	157	Shared Neighborhood Hits	117
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

GGA1_MOUSE
θ value	2.36792 (rank : 240)	NC score	0.031908 (rank : 606)
Query Neighborhood Hits	319	Target Neighborhood Hits	128	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GOGA2_HUMAN
θ value	2.36792 (rank : 241)	NC score	0.062628 (rank : 395)
Query Neighborhood Hits	319	Target Neighborhood Hits	856	Shared Neighborhood Hits	92
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

K1H2_HUMAN
θ value	2.36792 (rank : 242)	NC score	0.024964 (rank : 613)
Query Neighborhood Hits	319	Target Neighborhood Hits	492	Shared Neighborhood Hits	68
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

MPP6_HUMAN
θ value	2.36792 (rank : 243)	NC score	0.132527 (rank : 182)
Query Neighborhood Hits	319	Target Neighborhood Hits	180	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	2.36792 (rank : 244)	NC score	0.126885 (rank : 185)
Query Neighborhood Hits	319	Target Neighborhood Hits	187	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

NONO_HUMAN
θ value	2.36792 (rank : 245)	NC score	0.031426 (rank : 608)
Query Neighborhood Hits	319	Target Neighborhood Hits	441	Shared Neighborhood Hits	48
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

NONO_MOUSE
θ value	2.36792 (rank : 246)	NC score	0.031323 (rank : 609)
Query Neighborhood Hits	319	Target Neighborhood Hits	444	Shared Neighborhood Hits	48
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

NUCB1_MOUSE
θ value	2.36792 (rank : 247)	NC score	0.048255 (rank : 593)
Query Neighborhood Hits	319	Target Neighborhood Hits	414	Shared Neighborhood Hits	69
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

OPHN1_MOUSE
θ value	2.36792 (rank : 248)	NC score	0.058350 (rank : 450)
Query Neighborhood Hits	319	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RUSC2_MOUSE
θ value	2.36792 (rank : 249)	NC score	0.112544 (rank : 209)
Query Neighborhood Hits	319	Target Neighborhood Hits	305	Shared Neighborhood Hits	69
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

ANM2_MOUSE
θ value	3.0926 (rank : 250)	NC score	0.216883 (rank : 141)
Query Neighborhood Hits	319	Target Neighborhood Hits	175	Shared Neighborhood Hits	139
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

BI2L1_HUMAN
θ value	3.0926 (rank : 251)	NC score	0.125279 (rank : 187)
Query Neighborhood Hits	319	Target Neighborhood Hits	156	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CCDC7_HUMAN
θ value	3.0926 (rank : 252)	NC score	0.039082 (rank : 601)
Query Neighborhood Hits	319	Target Neighborhood Hits	253	Shared Neighborhood Hits	44
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

DMD_HUMAN
θ value	3.0926 (rank : 253)	NC score	0.056565 (rank : 479)
Query Neighborhood Hits	319	Target Neighborhood Hits	1135	Shared Neighborhood Hits	107
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

FRK_HUMAN
θ value	3.0926 (rank : 254)	NC score	0.109284 (rank : 216)
Query Neighborhood Hits	319	Target Neighborhood Hits	1058	Shared Neighborhood Hits	171
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

GOGA4_MOUSE
θ value	3.0926 (rank : 255)	NC score	0.072172 (rank : 305)
Query Neighborhood Hits	319	Target Neighborhood Hits	1939	Shared Neighborhood Hits	136
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

IF31_MOUSE
θ value	3.0926 (rank : 256)	NC score	0.046554 (rank : 594)
Query Neighborhood Hits	319	Target Neighborhood Hits	105	Shared Neighborhood Hits	21
SwissProt Accessions	Q66JS6, Q8BUW6	Gene names	Eif3s1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha).

MYH11_HUMAN
θ value	3.0926 (rank : 257)	NC score	0.076346 (rank : 280)
Query Neighborhood Hits	319	Target Neighborhood Hits	1806	Shared Neighborhood Hits	148
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	3.0926 (rank : 258)	NC score	0.076555 (rank : 278)
Query Neighborhood Hits	319	Target Neighborhood Hits	1777	Shared Neighborhood Hits	145
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH1_HUMAN
θ value	3.0926 (rank : 259)	NC score	0.071451 (rank : 312)
Query Neighborhood Hits	319	Target Neighborhood Hits	1478	Shared Neighborhood Hits	126
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

PCNT_HUMAN
θ value	3.0926 (rank : 260)	NC score	0.072440 (rank : 301)
Query Neighborhood Hits	319	Target Neighborhood Hits	1551	Shared Neighborhood Hits	135
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PCQAP_HUMAN
θ value	3.0926 (rank : 261)	NC score	0.033712 (rank : 605)
Query Neighborhood Hits	319	Target Neighborhood Hits	549	Shared Neighborhood Hits	45
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

STS1_MOUSE
θ value	3.0926 (rank : 262)	NC score	0.172728 (rank : 152)
Query Neighborhood Hits	319	Target Neighborhood Hits	104	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

TACC3_HUMAN
θ value	3.0926 (rank : 263)	NC score	0.053045 (rank : 541)
Query Neighborhood Hits	319	Target Neighborhood Hits	779	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

AKAP9_HUMAN
θ value	4.03905 (rank : 264)	NC score	0.061983 (rank : 406)
Query Neighborhood Hits	319	Target Neighborhood Hits	1710	Shared Neighborhood Hits	134
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

BRE1A_HUMAN
θ value	4.03905 (rank : 265)	NC score	0.065698 (rank : 365)
Query Neighborhood Hits	319	Target Neighborhood Hits	1071	Shared Neighborhood Hits	106
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	4.03905 (rank : 266)	NC score	0.063460 (rank : 389)
Query Neighborhood Hits	319	Target Neighborhood Hits	1025	Shared Neighborhood Hits	105
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CASC5_HUMAN
θ value	4.03905 (rank : 267)	NC score	0.070256 (rank : 320)
Query Neighborhood Hits	319	Target Neighborhood Hits	376	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CU013_HUMAN
θ value	4.03905 (rank : 268)	NC score	0.058102 (rank : 456)
Query Neighborhood Hits	319	Target Neighborhood Hits	405	Shared Neighborhood Hits	74
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

FIBP_HUMAN
θ value	4.03905 (rank : 269)	NC score	0.012776 (rank : 618)
Query Neighborhood Hits	319	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O43427, Q6IBQ3, Q9HD65	Gene names	FIBP
Domain Architecture
Description	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein).

GCC1_MOUSE
θ value	4.03905 (rank : 270)	NC score	0.053175 (rank : 538)
Query Neighborhood Hits	319	Target Neighborhood Hits	777	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOGA4_HUMAN
θ value	4.03905 (rank : 271)	NC score	0.068982 (rank : 331)
Query Neighborhood Hits	319	Target Neighborhood Hits	2034	Shared Neighborhood Hits	141
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

K0555_HUMAN
θ value	4.03905 (rank : 272)	NC score	0.077233 (rank : 275)
Query Neighborhood Hits	319	Target Neighborhood Hits	880	Shared Neighborhood Hits	106
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

KIF1A_HUMAN
θ value	4.03905 (rank : 273)	NC score	0.010153 (rank : 620)
Query Neighborhood Hits	319	Target Neighborhood Hits	240	Shared Neighborhood Hits	37
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1A_MOUSE
θ value	4.03905 (rank : 274)	NC score	0.009821 (rank : 621)
Query Neighborhood Hits	319	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

LYN_HUMAN
θ value	4.03905 (rank : 275)	NC score	0.106286 (rank : 225)
Query Neighborhood Hits	319	Target Neighborhood Hits	1022	Shared Neighborhood Hits	148
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M4K4_HUMAN
θ value	4.03905 (rank : 276)	NC score	0.034409 (rank : 604)
Query Neighborhood Hits	319	Target Neighborhood Hits	1589	Shared Neighborhood Hits	112
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

PTK6_MOUSE
θ value	4.03905 (rank : 277)	NC score	0.099663 (rank : 232)
Query Neighborhood Hits	319	Target Neighborhood Hits	1026	Shared Neighborhood Hits	149
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

STS1_HUMAN
θ value	4.03905 (rank : 278)	NC score	0.170512 (rank : 153)
Query Neighborhood Hits	319	Target Neighborhood Hits	106	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

BIN1_MOUSE
θ value	5.27518 (rank : 279)	NC score	0.118247 (rank : 197)
Query Neighborhood Hits	319	Target Neighborhood Hits	283	Shared Neighborhood Hits	83
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

BPAEA_MOUSE
θ value	5.27518 (rank : 280)	NC score	0.061075 (rank : 416)
Query Neighborhood Hits	319	Target Neighborhood Hits	1480	Shared Neighborhood Hits	124
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENPJ_HUMAN
θ value	5.27518 (rank : 281)	NC score	0.052305 (rank : 554)
Query Neighborhood Hits	319	Target Neighborhood Hits	721	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

HOME1_MOUSE
θ value	5.27518 (rank : 282)	NC score	0.045075 (rank : 596)
Query Neighborhood Hits	319	Target Neighborhood Hits	630	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

NIN_MOUSE
θ value	5.27518 (rank : 283)	NC score	0.060958 (rank : 418)
Query Neighborhood Hits	319	Target Neighborhood Hits	1376	Shared Neighborhood Hits	117
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

ROCK1_HUMAN
θ value	5.27518 (rank : 284)	NC score	0.043860 (rank : 597)
Query Neighborhood Hits	319	Target Neighborhood Hits	2000	Shared Neighborhood Hits	141
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

AAT1_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.029040 (rank : 611)
Query Neighborhood Hits	319	Target Neighborhood Hits	199	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

CBP_HUMAN
θ value	6.88961 (rank : 286)	NC score	0.011627 (rank : 619)
Query Neighborhood Hits	319	Target Neighborhood Hits	941	Shared Neighborhood Hits	24
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CING_MOUSE
θ value	6.88961 (rank : 287)	NC score	0.059377 (rank : 434)
Query Neighborhood Hits	319	Target Neighborhood Hits	1432	Shared Neighborhood Hits	115
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

DOCK1_HUMAN
θ value	6.88961 (rank : 288)	NC score	0.120250 (rank : 194)
Query Neighborhood Hits	319	Target Neighborhood Hits	191	Shared Neighborhood Hits	110
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

ES8L1_HUMAN
θ value	6.88961 (rank : 289)	NC score	0.169464 (rank : 155)
Query Neighborhood Hits	319	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

MYH9_MOUSE
θ value	6.88961 (rank : 290)	NC score	0.072487 (rank : 300)
Query Neighborhood Hits	319	Target Neighborhood Hits	1829	Shared Neighborhood Hits	139
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SAMN1_MOUSE
θ value	6.88961 (rank : 291)	NC score	0.100611 (rank : 231)
Query Neighborhood Hits	319	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

TPM1_HUMAN
θ value	6.88961 (rank : 292)	NC score	0.049194 (rank : 592)
Query Neighborhood Hits	319	Target Neighborhood Hits	716	Shared Neighborhood Hits	82
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	6.88961 (rank : 293)	NC score	0.049699 (rank : 591)
Query Neighborhood Hits	319	Target Neighborhood Hits	729	Shared Neighborhood Hits	83
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

USF2_HUMAN
θ value	6.88961 (rank : 294)	NC score	0.020369 (rank : 614)
Query Neighborhood Hits	319	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	6.88961 (rank : 295)	NC score	0.020216 (rank : 615)
Query Neighborhood Hits	319	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

CCD13_HUMAN
θ value	8.99809 (rank : 296)	NC score	0.060573 (rank : 421)
Query Neighborhood Hits	319	Target Neighborhood Hits	721	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD41_MOUSE
θ value	8.99809 (rank : 297)	NC score	0.064529 (rank : 380)
Query Neighborhood Hits	319	Target Neighborhood Hits	1399	Shared Neighborhood Hits	114
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CING_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.058019 (rank : 457)
Query Neighborhood Hits	319	Target Neighborhood Hits	1275	Shared Neighborhood Hits	114
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CIP4_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.168718 (rank : 156)
Query Neighborhood Hits	319	Target Neighborhood Hits	374	Shared Neighborhood Hits	115
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CP250_MOUSE
θ value	8.99809 (rank : 300)	NC score	0.066462 (rank : 354)
Query Neighborhood Hits	319	Target Neighborhood Hits	1583	Shared Neighborhood Hits	125
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DLG2_HUMAN
θ value	8.99809 (rank : 301)	NC score	0.064155 (rank : 384)
Query Neighborhood Hits	319	Target Neighborhood Hits	279	Shared Neighborhood Hits	75
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DMD_MOUSE
θ value	8.99809 (rank : 302)	NC score	0.054869 (rank : 513)
Query Neighborhood Hits	319	Target Neighborhood Hits	1111	Shared Neighborhood Hits	113
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

FYCO1_HUMAN
θ value	8.99809 (rank : 303)	NC score	0.050109 (rank : 587)
Query Neighborhood Hits	319	Target Neighborhood Hits	1149	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GRAP1_HUMAN
θ value	8.99809 (rank : 304)	NC score	0.054669 (rank : 518)
Query Neighborhood Hits	319	Target Neighborhood Hits	944	Shared Neighborhood Hits	104
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

K1H1_HUMAN
θ value	8.99809 (rank : 305)	NC score	0.014692 (rank : 617)
Query Neighborhood Hits	319	Target Neighborhood Hits	433	Shared Neighborhood Hits	61
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

K1H5_HUMAN
θ value	8.99809 (rank : 306)	NC score	0.009551 (rank : 622)
Query Neighborhood Hits	319	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q92764, O76012, Q92651	Gene names	KRTHA5, HHA5, HKA5
Domain Architecture
Description	Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5).

LIPA1_HUMAN
θ value	8.99809 (rank : 307)	NC score	0.062563 (rank : 397)
Query Neighborhood Hits	319	Target Neighborhood Hits	1294	Shared Neighborhood Hits	124
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MATK_HUMAN
θ value	8.99809 (rank : 308)	NC score	0.062381 (rank : 400)
Query Neighborhood Hits	319	Target Neighborhood Hits	954	Shared Neighborhood Hits	76
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MYH4_HUMAN
θ value	8.99809 (rank : 309)	NC score	0.066181 (rank : 356)
Query Neighborhood Hits	319	Target Neighborhood Hits	1377	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH6_MOUSE
θ value	8.99809 (rank : 310)	NC score	0.068939 (rank : 332)
Query Neighborhood Hits	319	Target Neighborhood Hits	1501	Shared Neighborhood Hits	125
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NIN_HUMAN
θ value	8.99809 (rank : 311)	NC score	0.061033 (rank : 417)
Query Neighborhood Hits	319	Target Neighborhood Hits	1416	Shared Neighborhood Hits	119
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NPHP1_HUMAN
θ value	8.99809 (rank : 312)	NC score	0.309149 (rank : 109)
Query Neighborhood Hits	319	Target Neighborhood Hits	288	Shared Neighborhood Hits	166
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

SAMN1_HUMAN
θ value	8.99809 (rank : 313)	NC score	0.097925 (rank : 233)
Query Neighborhood Hits	319	Target Neighborhood Hits	74	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

SASH1_HUMAN
θ value	8.99809 (rank : 314)	NC score	0.095640 (rank : 238)
Query Neighborhood Hits	319	Target Neighborhood Hits	292	Shared Neighborhood Hits	60
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SASH1_MOUSE
θ value	8.99809 (rank : 315)	NC score	0.090293 (rank : 249)
Query Neighborhood Hits	319	Target Neighborhood Hits	263	Shared Neighborhood Hits	57
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SFPQ_MOUSE
θ value	8.99809 (rank : 316)	NC score	0.031483 (rank : 607)
Query Neighborhood Hits	319	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

TRI18_HUMAN
θ value	8.99809 (rank : 317)	NC score	0.003856 (rank : 624)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	8.99809 (rank : 318)	NC score	0.004355 (rank : 623)
Query Neighborhood Hits	319	Target Neighborhood Hits	292	Shared Neighborhood Hits	11
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

ZN384_HUMAN
θ value	8.99809 (rank : 319)	NC score	-0.010336 (rank : 625)
Query Neighborhood Hits	319	Target Neighborhood Hits	764	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF68, O15407, Q8N938	Gene names	ZNF384, CAGH1, CIZ, NMP4
Domain Architecture	No domain graphic available
Description	Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein).

ABL1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.084996 (rank : 260)
Query Neighborhood Hits	319	Target Neighborhood Hits	1220	Shared Neighborhood Hits	126
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.084906 (rank : 261)
Query Neighborhood Hits	319	Target Neighborhood Hits	1178	Shared Neighborhood Hits	126
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.081779 (rank : 267)
Query Neighborhood Hits	319	Target Neighborhood Hits	1045	Shared Neighborhood Hits	116
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ABR_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.065903 (rank : 363)
Query Neighborhood Hits	319	Target Neighborhood Hits	166	Shared Neighborhood Hits	31
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

AMPH_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.150445 (rank : 164)
Query Neighborhood Hits	319	Target Neighborhood Hits	455	Shared Neighborhood Hits	102
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.125148 (rank : 188)
Query Neighborhood Hits	319	Target Neighborhood Hits	291	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANR26_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.052653 (rank : 545)
Query Neighborhood Hits	319	Target Neighborhood Hits	1614	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR26_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.054691 (rank : 517)
Query Neighborhood Hits	319	Target Neighborhood Hits	1554	Shared Neighborhood Hits	119
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

APS_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.077351 (rank : 273)
Query Neighborhood Hits	319	Target Neighborhood Hits	162	Shared Neighborhood Hits	39
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

APS_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.058615 (rank : 447)
Query Neighborhood Hits	319	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

ARHG1_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.074028 (rank : 291)
Query Neighborhood Hits	319	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.062087 (rank : 403)
Query Neighborhood Hits	319	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG2_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.065061 (rank : 372)
Query Neighborhood Hits	319	Target Neighborhood Hits	142	Shared Neighborhood Hits	26
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.064322 (rank : 382)
Query Neighborhood Hits	319	Target Neighborhood Hits	120	Shared Neighborhood Hits	24
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.107080 (rank : 223)
Query Neighborhood Hits	319	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.107118 (rank : 222)
Query Neighborhood Hits	319	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG8_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.095942 (rank : 237)
Query Neighborhood Hits	319	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.104674 (rank : 226)
Query Neighborhood Hits	319	Target Neighborhood Hits	79	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGA_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.089651 (rank : 250)
Query Neighborhood Hits	319	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.094640 (rank : 242)
Query Neighborhood Hits	319	Target Neighborhood Hits	125	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.074223 (rank : 289)
Query Neighborhood Hits	319	Target Neighborhood Hits	375	Shared Neighborhood Hits	34
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.076369 (rank : 279)
Query Neighborhood Hits	319	Target Neighborhood Hits	351	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.075071 (rank : 286)
Query Neighborhood Hits	319	Target Neighborhood Hits	344	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.068879 (rank : 334)
Query Neighborhood Hits	319	Target Neighborhood Hits	214	Shared Neighborhood Hits	24
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARHGG_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.108168 (rank : 219)
Query Neighborhood Hits	319	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHGG_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.123188 (rank : 191)
Query Neighborhood Hits	319	Target Neighborhood Hits	152	Shared Neighborhood Hits	62
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

AZI1_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.065972 (rank : 360)
Query Neighborhood Hits	319	Target Neighborhood Hits	1000	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BCAR3_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.055232 (rank : 507)
Query Neighborhood Hits	319	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

BCAR3_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.054258 (rank : 520)
Query Neighborhood Hits	319	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

BCR_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.074470 (rank : 287)
Query Neighborhood Hits	319	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BI2L1_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.103154 (rank : 228)
Query Neighborhood Hits	319	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BICD2_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.050391 (rank : 581)
Query Neighborhood Hits	319	Target Neighborhood Hits	856	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BIN1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.112678 (rank : 208)
Query Neighborhood Hits	319	Target Neighborhood Hits	335	Shared Neighborhood Hits	81
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BLK_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.097919 (rank : 234)
Query Neighborhood Hits	319	Target Neighborhood Hits	994	Shared Neighborhood Hits	135
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.094809 (rank : 241)
Query Neighborhood Hits	319	Target Neighborhood Hits	992	Shared Neighborhood Hits	125
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BRE1B_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.055303 (rank : 506)
Query Neighborhood Hits	319	Target Neighborhood Hits	1040	Shared Neighborhood Hits	93
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CARD9_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.059092 (rank : 439)
Query Neighborhood Hits	319	Target Neighborhood Hits	602	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CASP_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.055683 (rank : 495)
Query Neighborhood Hits	319	Target Neighborhood Hits	1131	Shared Neighborhood Hits	110
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.056940 (rank : 473)
Query Neighborhood Hits	319	Target Neighborhood Hits	1152	Shared Neighborhood Hits	116
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCD19_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.050462 (rank : 577)
Query Neighborhood Hits	319	Target Neighborhood Hits	639	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.058178 (rank : 454)
Query Neighborhood Hits	319	Target Neighborhood Hits	1228	Shared Neighborhood Hits	112
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.059130 (rank : 438)
Query Neighborhood Hits	319	Target Neighborhood Hits	1135	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD39_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.054138 (rank : 522)
Query Neighborhood Hits	319	Target Neighborhood Hits	868	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.056692 (rank : 477)
Query Neighborhood Hits	319	Target Neighborhood Hits	1026	Shared Neighborhood Hits	103
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.053612 (rank : 531)
Query Neighborhood Hits	319	Target Neighborhood Hits	1139	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD46_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.068270 (rank : 341)
Query Neighborhood Hits	319	Target Neighborhood Hits	1430	Shared Neighborhood Hits	132
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.066038 (rank : 359)
Query Neighborhood Hits	319	Target Neighborhood Hits	1405	Shared Neighborhood Hits	127
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCD91_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.055756 (rank : 494)
Query Neighborhood Hits	319	Target Neighborhood Hits	868	Shared Neighborhood Hits	89
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCD96_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.051077 (rank : 569)
Query Neighborhood Hits	319	Target Neighborhood Hits	595	Shared Neighborhood Hits	72
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD96_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.050453 (rank : 578)
Query Neighborhood Hits	319	Target Neighborhood Hits	704	Shared Neighborhood Hits	77
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.050399 (rank : 580)
Query Neighborhood Hits	319	Target Neighborhood Hits	723	Shared Neighborhood Hits	90
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CE152_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.057655 (rank : 465)
Query Neighborhood Hits	319	Target Neighborhood Hits	976	Shared Neighborhood Hits	101
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.061736 (rank : 410)
Query Neighborhood Hits	319	Target Neighborhood Hits	1553	Shared Neighborhood Hits	125
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPE_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.055659 (rank : 496)
Query Neighborhood Hits	319	Target Neighborhood Hits	2060	Shared Neighborhood Hits	145
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CENPF_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.063228 (rank : 391)
Query Neighborhood Hits	319	Target Neighborhood Hits	1932	Shared Neighborhood Hits	145
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP63_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.061553 (rank : 412)
Query Neighborhood Hits	319	Target Neighborhood Hits	1005	Shared Neighborhood Hits	104
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CF060_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.059613 (rank : 430)
Query Neighborhood Hits	319	Target Neighborhood Hits	1270	Shared Neighborhood Hits	118
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CHIN_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.068358 (rank : 340)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	47
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.069721 (rank : 325)
Query Neighborhood Hits	319	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.067883 (rank : 343)
Query Neighborhood Hits	319	Target Neighborhood Hits	220	Shared Neighborhood Hits	45
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CI039_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.055560 (rank : 498)
Query Neighborhood Hits	319	Target Neighborhood Hits	1171	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.062877 (rank : 392)
Query Neighborhood Hits	319	Target Neighborhood Hits	1088	Shared Neighborhood Hits	109
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CJ118_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.050440 (rank : 579)
Query Neighborhood Hits	319	Target Neighborhood Hits	1132	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CK5P2_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.058786 (rank : 445)
Query Neighborhood Hits	319	Target Neighborhood Hits	1433	Shared Neighborhood Hits	121
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.050984 (rank : 571)
Query Neighborhood Hits	319	Target Neighborhood Hits	1151	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CN145_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.055970 (rank : 486)
Query Neighborhood Hits	319	Target Neighborhood Hits	1196	Shared Neighborhood Hits	111
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CNTRB_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.060896 (rank : 419)
Query Neighborhood Hits	319	Target Neighborhood Hits	1029	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP135_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.058249 (rank : 452)
Query Neighborhood Hits	319	Target Neighborhood Hits	1290	Shared Neighborhood Hits	114
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.058557 (rank : 449)
Query Neighborhood Hits	319	Target Neighborhood Hits	1278	Shared Neighborhood Hits	111
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP250_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.065218 (rank : 371)
Query Neighborhood Hits	319	Target Neighborhood Hits	1805	Shared Neighborhood Hits	135
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CROCC_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.057252 (rank : 470)
Query Neighborhood Hits	319	Target Neighborhood Hits	1460	Shared Neighborhood Hits	117
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CSK_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.102097 (rank : 230)
Query Neighborhood Hits	319	Target Neighborhood Hits	1009	Shared Neighborhood Hits	134
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.102335 (rank : 229)
Query Neighborhood Hits	319	Target Neighborhood Hits	1009	Shared Neighborhood Hits	134
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CT2NL_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.055918 (rank : 488)
Query Neighborhood Hits	319	Target Neighborhood Hits	1059	Shared Neighborhood Hits	103
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CUTL1_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.050641 (rank : 574)
Query Neighborhood Hits	319	Target Neighborhood Hits	1574	Shared Neighborhood Hits	111
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.052056 (rank : 558)
Query Neighborhood Hits	319	Target Neighborhood Hits	1620	Shared Neighborhood Hits	111
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CYLN2_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.064540 (rank : 379)
Query Neighborhood Hits	319	Target Neighborhood Hits	1004	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.065655 (rank : 366)
Query Neighborhood Hits	319	Target Neighborhood Hits	1002	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CYTSA_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.051501 (rank : 563)
Query Neighborhood Hits	319	Target Neighborhood Hits	1138	Shared Neighborhood Hits	112
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.051292 (rank : 564)
Query Neighborhood Hits	319	Target Neighborhood Hits	1104	Shared Neighborhood Hits	108
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DAPP1_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.088330 (rank : 253)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.088548 (rank : 252)
Query Neighborhood Hits	319	Target Neighborhood Hits	225	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDFL1_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.050787 (rank : 572)
Query Neighborhood Hits	319	Target Neighborhood Hits	353	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DESP_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.062615 (rank : 396)
Query Neighborhood Hits	319	Target Neighborhood Hits	1470	Shared Neighborhood Hits	131
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DLG1_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.055815 (rank : 492)
Query Neighborhood Hits	319	Target Neighborhood Hits	290	Shared Neighborhood Hits	67
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.053453 (rank : 532)
Query Neighborhood Hits	319	Target Neighborhood Hits	285	Shared Neighborhood Hits	66
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG2_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.062095 (rank : 402)
Query Neighborhood Hits	319	Target Neighborhood Hits	271	Shared Neighborhood Hits	75
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.060162 (rank : 425)
Query Neighborhood Hits	319	Target Neighborhood Hits	269	Shared Neighborhood Hits	72
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.059557 (rank : 431)
Query Neighborhood Hits	319	Target Neighborhood Hits	274	Shared Neighborhood Hits	72
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG4_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.056465 (rank : 481)
Query Neighborhood Hits	319	Target Neighborhood Hits	286	Shared Neighborhood Hits	71
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.054237 (rank : 521)
Query Neighborhood Hits	319	Target Neighborhood Hits	282	Shared Neighborhood Hits	69
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG5_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.061318 (rank : 414)
Query Neighborhood Hits	319	Target Neighborhood Hits	1088	Shared Neighborhood Hits	138
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DREB_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.051067 (rank : 570)
Query Neighborhood Hits	319	Target Neighborhood Hits	450	Shared Neighborhood Hits	56
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

DREB_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.052363 (rank : 553)
Query Neighborhood Hits	319	Target Neighborhood Hits	446	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

ECT2_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.082829 (rank : 266)
Query Neighborhood Hits	319	Target Neighborhood Hits	98	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.085812 (rank : 258)
Query Neighborhood Hits	319	Target Neighborhood Hits	98	Shared Neighborhood Hits	22
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

EP15R_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.066840 (rank : 351)
Query Neighborhood Hits	319	Target Neighborhood Hits	1083	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.068510 (rank : 339)
Query Neighborhood Hits	319	Target Neighborhood Hits	1135	Shared Neighborhood Hits	102
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

ES8L1_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.155609 (rank : 160)
Query Neighborhood Hits	319	Target Neighborhood Hits	143	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

EVPL_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.050203 (rank : 584)
Query Neighborhood Hits	319	Target Neighborhood Hits	895	Shared Neighborhood Hits	94
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.053194 (rank : 537)
Query Neighborhood Hits	319	Target Neighborhood Hits	952	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FARP1_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.050102 (rank : 588)
Query Neighborhood Hits	319	Target Neighborhood Hits	241	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.051260 (rank : 565)
Query Neighborhood Hits	319	Target Neighborhood Hits	240	Shared Neighborhood Hits	23
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.056033 (rank : 485)
Query Neighborhood Hits	319	Target Neighborhood Hits	209	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FER_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.057603 (rank : 466)
Query Neighborhood Hits	319	Target Neighborhood Hits	1278	Shared Neighborhood Hits	123
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FGD1_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.060369 (rank : 423)
Query Neighborhood Hits	319	Target Neighborhood Hits	367	Shared Neighborhood Hits	36
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.057751 (rank : 463)
Query Neighborhood Hits	319	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.069347 (rank : 328)
Query Neighborhood Hits	319	Target Neighborhood Hits	151	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.065394 (rank : 369)
Query Neighborhood Hits	319	Target Neighborhood Hits	163	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.066589 (rank : 352)
Query Neighborhood Hits	319	Target Neighborhood Hits	249	Shared Neighborhood Hits	27
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.071195 (rank : 316)
Query Neighborhood Hits	319	Target Neighborhood Hits	257	Shared Neighborhood Hits	29
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.071835 (rank : 307)
Query Neighborhood Hits	319	Target Neighborhood Hits	219	Shared Neighborhood Hits	35
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.072325 (rank : 302)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD6_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.050067 (rank : 589)
Query Neighborhood Hits	319	Target Neighborhood Hits	237	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.055773 (rank : 493)
Query Neighborhood Hits	319	Target Neighborhood Hits	282	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FLIP1_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.063228 (rank : 390)
Query Neighborhood Hits	319	Target Neighborhood Hits	1405	Shared Neighborhood Hits	125
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.056400 (rank : 482)
Query Neighborhood Hits	319	Target Neighborhood Hits	1176	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FUT8_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.065959 (rank : 361)
Query Neighborhood Hits	319	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYC5, O00235, Q9BYC6, Q9P2U5, Q9P2U6	Gene names	FUT8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

FUT8_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.065451 (rank : 368)
Query Neighborhood Hits	319	Target Neighborhood Hits	115	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

GAS8_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.058015 (rank : 458)
Query Neighborhood Hits	319	Target Neighborhood Hits	819	Shared Neighborhood Hits	98
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCC1_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.051577 (rank : 561)
Query Neighborhood Hits	319	Target Neighborhood Hits	887	Shared Neighborhood Hits	89
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC2_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.063653 (rank : 388)
Query Neighborhood Hits	319	Target Neighborhood Hits	1619	Shared Neighborhood Hits	129
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GNRP_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.061995 (rank : 405)
Query Neighborhood Hits	319	Target Neighborhood Hits	239	Shared Neighborhood Hits	29
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.068692 (rank : 337)
Query Neighborhood Hits	319	Target Neighborhood Hits	191	Shared Neighborhood Hits	27
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GOGA1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.060109 (rank : 426)
Query Neighborhood Hits	319	Target Neighborhood Hits	1222	Shared Neighborhood Hits	110
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA1_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.059189 (rank : 436)
Query Neighborhood Hits	319	Target Neighborhood Hits	994	Shared Neighborhood Hits	106
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.059685 (rank : 429)
Query Neighborhood Hits	319	Target Neighborhood Hits	944	Shared Neighborhood Hits	101
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.058694 (rank : 446)
Query Neighborhood Hits	319	Target Neighborhood Hits	1317	Shared Neighborhood Hits	113
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.066145 (rank : 357)
Query Neighborhood Hits	319	Target Neighborhood Hits	1437	Shared Neighborhood Hits	124
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA5_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.061768 (rank : 408)
Query Neighborhood Hits	319	Target Neighborhood Hits	1168	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.057761 (rank : 462)
Query Neighborhood Hits	319	Target Neighborhood Hits	1007	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GOGB1_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.064790 (rank : 377)
Query Neighborhood Hits	319	Target Neighborhood Hits	2297	Shared Neighborhood Hits	143
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRAP1_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.058575 (rank : 448)
Query Neighborhood Hits	319	Target Neighborhood Hits	1234	Shared Neighborhood Hits	112
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRB10_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.057684 (rank : 464)
Query Neighborhood Hits	319	Target Neighborhood Hits	147	Shared Neighborhood Hits	41
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.058330 (rank : 451)
Query Neighborhood Hits	319	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB14_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.077695 (rank : 271)
Query Neighborhood Hits	319	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB14_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.079654 (rank : 269)
Query Neighborhood Hits	319	Target Neighborhood Hits	149	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

GRB7_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.062021 (rank : 404)
Query Neighborhood Hits	319	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB7_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.069385 (rank : 327)
Query Neighborhood Hits	319	Target Neighborhood Hits	157	Shared Neighborhood Hits	42
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

HAPIP_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.087716 (rank : 255)
Query Neighborhood Hits	319	Target Neighborhood Hits	350	Shared Neighborhood Hits	66
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HIP1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.050613 (rank : 575)
Query Neighborhood Hits	319	Target Neighborhood Hits	1016	Shared Neighborhood Hits	103
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HMMR_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.054868 (rank : 514)
Query Neighborhood Hits	319	Target Neighborhood Hits	1082	Shared Neighborhood Hits	100
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.056744 (rank : 476)
Query Neighborhood Hits	319	Target Neighborhood Hits	1178	Shared Neighborhood Hits	108
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOME2_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.055407 (rank : 503)
Query Neighborhood Hits	319	Target Neighborhood Hits	882	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

HOOK1_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.052519 (rank : 550)
Query Neighborhood Hits	319	Target Neighborhood Hits	910	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.052552 (rank : 547)
Query Neighborhood Hits	319	Target Neighborhood Hits	714	Shared Neighborhood Hits	88
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HOOK3_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.062785 (rank : 394)
Query Neighborhood Hits	319	Target Neighborhood Hits	1070	Shared Neighborhood Hits	108
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.061279 (rank : 415)
Query Neighborhood Hits	319	Target Neighborhood Hits	1007	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HSH2D_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.070256 (rank : 321)
Query Neighborhood Hits	319	Target Neighborhood Hits	159	Shared Neighborhood Hits	34
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

IFT74_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.057848 (rank : 460)
Query Neighborhood Hits	319	Target Neighborhood Hits	949	Shared Neighborhood Hits	101
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.055167 (rank : 508)
Query Neighborhood Hits	319	Target Neighborhood Hits	939	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.055144 (rank : 509)
Query Neighborhood Hits	319	Target Neighborhood Hits	893	Shared Neighborhood Hits	95
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.056148 (rank : 484)
Query Neighborhood Hits	319	Target Neighborhood Hits	959	Shared Neighborhood Hits	91
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INCE_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.052874 (rank : 542)
Query Neighborhood Hits	319	Target Neighborhood Hits	978	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.055033 (rank : 512)
Query Neighborhood Hits	319	Target Neighborhood Hits	903	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INVO_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.055446 (rank : 502)
Query Neighborhood Hits	319	Target Neighborhood Hits	636	Shared Neighborhood Hits	75
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

ITK_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.082891 (rank : 265)
Query Neighborhood Hits	319	Target Neighborhood Hits	1016	Shared Neighborhood Hits	128
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.075313 (rank : 284)
Query Neighborhood Hits	319	Target Neighborhood Hits	985	Shared Neighborhood Hits	115
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JIP2_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.084400 (rank : 262)
Query Neighborhood Hits	319	Target Neighborhood Hits	288	Shared Neighborhood Hits	57
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

JIP2_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.085207 (rank : 259)
Query Neighborhood Hits	319	Target Neighborhood Hits	144	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

KTN1_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.058194 (rank : 453)
Query Neighborhood Hits	319	Target Neighborhood Hits	1324	Shared Neighborhood Hits	120
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LBC_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.069969 (rank : 323)
Query Neighborhood Hits	319	Target Neighborhood Hits	90	Shared Neighborhood Hits	24
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

LCP2_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.052069 (rank : 556)
Query Neighborhood Hits	319	Target Neighborhood Hits	531	Shared Neighborhood Hits	51
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LCP2_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.055124 (rank : 510)
Query Neighborhood Hits	319	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LIPA2_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.055515 (rank : 500)
Query Neighborhood Hits	319	Target Neighborhood Hits	1044	Shared Neighborhood Hits	108
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.064097 (rank : 385)
Query Neighborhood Hits	319	Target Neighborhood Hits	1282	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LNK_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.067632 (rank : 345)
Query Neighborhood Hits	319	Target Neighborhood Hits	151	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LNK_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.065926 (rank : 362)
Query Neighborhood Hits	319	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

LRC45_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.053266 (rank : 535)
Query Neighborhood Hits	319	Target Neighborhood Hits	933	Shared Neighborhood Hits	100
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.053766 (rank : 528)
Query Neighborhood Hits	319	Target Neighborhood Hits	959	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF2_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.053902 (rank : 524)
Query Neighborhood Hits	319	Target Neighborhood Hits	791	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LYN_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.104308 (rank : 227)
Query Neighborhood Hits	319	Target Neighborhood Hits	1023	Shared Neighborhood Hits	148
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MACF4_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.052253 (rank : 555)
Query Neighborhood Hits	319	Target Neighborhood Hits	1321	Shared Neighborhood Hits	105
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACOI_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.050384 (rank : 582)
Query Neighborhood Hits	319	Target Neighborhood Hits	650	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.050192 (rank : 585)
Query Neighborhood Hits	319	Target Neighborhood Hits	620	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MCF2L_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.112684 (rank : 207)
Query Neighborhood Hits	319	Target Neighborhood Hits	255	Shared Neighborhood Hits	63
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.094883 (rank : 240)
Query Neighborhood Hits	319	Target Neighborhood Hits	166	Shared Neighborhood Hits	35
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MD1L1_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.053320 (rank : 534)
Query Neighborhood Hits	319	Target Neighborhood Hits	1001	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MPP3_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.065225 (rank : 370)
Query Neighborhood Hits	319	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.064921 (rank : 376)
Query Neighborhood Hits	319	Target Neighborhood Hits	165	Shared Neighborhood Hits	37
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.075242 (rank : 285)
Query Neighborhood Hits	319	Target Neighborhood Hits	205	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP4_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.081182 (rank : 268)
Query Neighborhood Hits	319	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MY18B_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.066545 (rank : 353)
Query Neighborhood Hits	319	Target Neighborhood Hits	1299	Shared Neighborhood Hits	105
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH10_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.069113 (rank : 329)
Query Neighborhood Hits	319	Target Neighborhood Hits	1620	Shared Neighborhood Hits	135
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.068911 (rank : 333)
Query Neighborhood Hits	319	Target Neighborhood Hits	1612	Shared Neighborhood Hits	135
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH14_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.062534 (rank : 398)
Query Neighborhood Hits	319	Target Neighborhood Hits	995	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.065804 (rank : 364)
Query Neighborhood Hits	319	Target Neighborhood Hits	1225	Shared Neighborhood Hits	110
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH3_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.071055 (rank : 317)
Query Neighborhood Hits	319	Target Neighborhood Hits	1660	Shared Neighborhood Hits	135
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH6_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.067510 (rank : 346)
Query Neighborhood Hits	319	Target Neighborhood Hits	1426	Shared Neighborhood Hits	116
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.067037 (rank : 348)
Query Neighborhood Hits	319	Target Neighborhood Hits	1559	Shared Neighborhood Hits	119
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH8_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.070098 (rank : 322)
Query Neighborhood Hits	319	Target Neighborhood Hits	1610	Shared Neighborhood Hits	132
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.071330 (rank : 314)
Query Neighborhood Hits	319	Target Neighborhood Hits	1600	Shared Neighborhood Hits	134
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH9_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.071560 (rank : 310)
Query Neighborhood Hits	319	Target Neighborhood Hits	1762	Shared Neighborhood Hits	138
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO10_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.059254 (rank : 435)
Query Neighborhood Hits	319	Target Neighborhood Hits	920	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO15_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.052495 (rank : 551)
Query Neighborhood Hits	319	Target Neighborhood Hits	467	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO5A_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.064295 (rank : 383)
Query Neighborhood Hits	319	Target Neighborhood Hits	1092	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.061883 (rank : 407)
Query Neighborhood Hits	319	Target Neighborhood Hits	1117	Shared Neighborhood Hits	104
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5B_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.057062 (rank : 471)
Query Neighborhood Hits	319	Target Neighborhood Hits	911	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO5C_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.066973 (rank : 350)
Query Neighborhood Hits	319	Target Neighborhood Hits	1206	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYO6_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.057028 (rank : 472)
Query Neighborhood Hits	319	Target Neighborhood Hits	727	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO6_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.055943 (rank : 487)
Query Neighborhood Hits	319	Target Neighborhood Hits	586	Shared Neighborhood Hits	69
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO9B_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.053619 (rank : 530)
Query Neighborhood Hits	319	Target Neighborhood Hits	641	Shared Neighborhood Hits	44
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.053718 (rank : 529)
Query Neighborhood Hits	319	Target Neighborhood Hits	311	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NAF1_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.051626 (rank : 560)
Query Neighborhood Hits	319	Target Neighborhood Hits	937	Shared Neighborhood Hits	94
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NDE1_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.062211 (rank : 401)
Query Neighborhood Hits	319	Target Neighborhood Hits	823	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NEMO_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.052530 (rank : 549)
Query Neighborhood Hits	319	Target Neighborhood Hits	820	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NGEF_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.145681 (rank : 170)
Query Neighborhood Hits	319	Target Neighborhood Hits	166	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.143936 (rank : 173)
Query Neighborhood Hits	319	Target Neighborhood Hits	228	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NOXO1_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.158542 (rank : 158)
Query Neighborhood Hits	319	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.221987 (rank : 140)
Query Neighborhood Hits	319	Target Neighborhood Hits	114	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NRAP_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.050583 (rank : 576)
Query Neighborhood Hits	319	Target Neighborhood Hits	167	Shared Neighborhood Hits	21
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

NUMA1_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.061693 (rank : 411)
Query Neighborhood Hits	319	Target Neighborhood Hits	1523	Shared Neighborhood Hits	125
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

OPTN_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.050124 (rank : 586)
Query Neighborhood Hits	319	Target Neighborhood Hits	827	Shared Neighborhood Hits	93
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.058888 (rank : 442)
Query Neighborhood Hits	319	Target Neighborhood Hits	1120	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

P55G_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.094203 (rank : 243)
Query Neighborhood Hits	319	Target Neighborhood Hits	451	Shared Neighborhood Hits	105
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.090663 (rank : 247)
Query Neighborhood Hits	319	Target Neighborhood Hits	401	Shared Neighborhood Hits	95
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85A_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.135093 (rank : 180)
Query Neighborhood Hits	319	Target Neighborhood Hits	479	Shared Neighborhood Hits	135
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.145550 (rank : 171)
Query Neighborhood Hits	319	Target Neighborhood Hits	435	Shared Neighborhood Hits	127
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.117155 (rank : 199)
Query Neighborhood Hits	319	Target Neighborhood Hits	543	Shared Neighborhood Hits	121
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.110858 (rank : 213)
Query Neighborhood Hits	319	Target Neighborhood Hits	519	Shared Neighborhood Hits	121
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PEPL_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.058859 (rank : 444)
Query Neighborhood Hits	319	Target Neighborhood Hits	1141	Shared Neighborhood Hits	105
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.062829 (rank : 393)
Query Neighborhood Hits	319	Target Neighborhood Hits	1105	Shared Neighborhood Hits	113
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PIBF1_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.061355 (rank : 413)
Query Neighborhood Hits	319	Target Neighborhood Hits	1041	Shared Neighborhood Hits	103
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PKHG1_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.118473 (rank : 196)
Query Neighborhood Hits	319	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PKHG4_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.059783 (rank : 428)
Query Neighborhood Hits	319	Target Neighborhood Hits	200	Shared Neighborhood Hits	21
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PLCB1_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.057452 (rank : 468)
Query Neighborhood Hits	319	Target Neighborhood Hits	614	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB1_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.052537 (rank : 548)
Query Neighborhood Hits	319	Target Neighborhood Hits	531	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PLCB2_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.054809 (rank : 515)
Query Neighborhood Hits	319	Target Neighborhood Hits	608	Shared Neighborhood Hits	76
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

PLCB4_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.059010 (rank : 440)
Query Neighborhood Hits	319	Target Neighborhood Hits	658	Shared Neighborhood Hits	82
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

PLEC1_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.051703 (rank : 559)
Query Neighborhood Hits	319	Target Neighborhood Hits	1326	Shared Neighborhood Hits	112
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PPIP2_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.091657 (rank : 246)
Query Neighborhood Hits	319	Target Neighborhood Hits	254	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

PPIP2_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.087815 (rank : 254)
Query Neighborhood Hits	319	Target Neighborhood Hits	308	Shared Neighborhood Hits	69
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PREX1_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.113159 (rank : 205)
Query Neighborhood Hits	319	Target Neighborhood Hits	177	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PTK6_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.096075 (rank : 236)
Query Neighborhood Hits	319	Target Neighborhood Hits	1020	Shared Neighborhood Hits	152
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTN11_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.055333 (rank : 504)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	45
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.055315 (rank : 505)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	44
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

RABE1_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.055911 (rank : 489)
Query Neighborhood Hits	319	Target Neighborhood Hits	1104	Shared Neighborhood Hits	107
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.053086 (rank : 540)
Query Neighborhood Hits	319	Target Neighborhood Hits	1105	Shared Neighborhood Hits	109
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RAD50_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.063739 (rank : 386)
Query Neighborhood Hits	319	Target Neighborhood Hits	1317	Shared Neighborhood Hits	116
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RASA1_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.107605 (rank : 221)
Query Neighborhood Hits	319	Target Neighborhood Hits	258	Shared Neighborhood Hits	63
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RB6I2_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.063658 (rank : 387)
Query Neighborhood Hits	319	Target Neighborhood Hits	1584	Shared Neighborhood Hits	120
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.065008 (rank : 374)
Query Neighborhood Hits	319	Target Neighborhood Hits	1433	Shared Neighborhood Hits	116
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

REST_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.066120 (rank : 358)
Query Neighborhood Hits	319	Target Neighborhood Hits	1605	Shared Neighborhood Hits	124
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.059926 (rank : 427)
Query Neighborhood Hits	319	Target Neighborhood Hits	1506	Shared Neighborhood Hits	112
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFIP3_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.052605 (rank : 546)
Query Neighborhood Hits	319	Target Neighborhood Hits	1055	Shared Neighborhood Hits	100
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RGNEF_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.086576 (rank : 257)
Query Neighborhood Hits	319	Target Neighborhood Hits	641	Shared Neighborhood Hits	99
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RHG09_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.056188 (rank : 483)
Query Neighborhood Hits	319	Target Neighborhood Hits	186	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.056500 (rank : 480)
Query Neighborhood Hits	319	Target Neighborhood Hits	190	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.058876 (rank : 443)
Query Neighborhood Hits	319	Target Neighborhood Hits	204	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RRBP1_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.055861 (rank : 491)
Query Neighborhood Hits	319	Target Neighborhood Hits	1650	Shared Neighborhood Hits	116
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RUFY2_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.052062 (rank : 557)
Query Neighborhood Hits	319	Target Neighborhood Hits	1208	Shared Neighborhood Hits	105
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

S3TC2_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.055532 (rank : 499)
Query Neighborhood Hits	319	Target Neighborhood Hits	83	Shared Neighborhood Hits	44
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

SDCG8_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.055864 (rank : 490)
Query Neighborhood Hits	319	Target Neighborhood Hits	1002	Shared Neighborhood Hits	93
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SH21A_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.061754 (rank : 409)
Query Neighborhood Hits	319	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.062444 (rank : 399)
Query Neighborhood Hits	319	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SH21B_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.087527 (rank : 256)
Query Neighborhood Hits	319	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH21B_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.091944 (rank : 245)
Query Neighborhood Hits	319	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

SH22A_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.057576 (rank : 467)
Query Neighborhood Hits	319	Target Neighborhood Hits	179	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SH24A_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.068851 (rank : 335)
Query Neighborhood Hits	319	Target Neighborhood Hits	455	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

SH2D3_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.055584 (rank : 497)
Query Neighborhood Hits	319	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SH2D3_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.058955 (rank : 441)
Query Neighborhood Hits	319	Target Neighborhood Hits	174	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SHB_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.072230 (rank : 303)
Query Neighborhood Hits	319	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHB_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.074223 (rank : 290)
Query Neighborhood Hits	319	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC1_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.076745 (rank : 276)
Query Neighborhood Hits	319	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.076691 (rank : 277)
Query Neighborhood Hits	319	Target Neighborhood Hits	180	Shared Neighborhood Hits	47
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC2_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.071431 (rank : 313)
Query Neighborhood Hits	319	Target Neighborhood Hits	170	Shared Neighborhood Hits	45
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

SHC2_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.071862 (rank : 306)
Query Neighborhood Hits	319	Target Neighborhood Hits	144	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SHC3_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.072217 (rank : 304)
Query Neighborhood Hits	319	Target Neighborhood Hits	155	Shared Neighborhood Hits	41
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SHC3_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.077689 (rank : 272)
Query Neighborhood Hits	319	Target Neighborhood Hits	151	Shared Neighborhood Hits	46
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

SHD_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.068555 (rank : 338)
Query Neighborhood Hits	319	Target Neighborhood Hits	204	Shared Neighborhood Hits	40
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHD_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.071688 (rank : 309)
Query Neighborhood Hits	319	Target Neighborhood Hits	137	Shared Neighborhood Hits	42
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHE_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.073970 (rank : 293)
Query Neighborhood Hits	319	Target Neighborhood Hits	164	Shared Neighborhood Hits	43
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SHE_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.077292 (rank : 274)
Query Neighborhood Hits	319	Target Neighborhood Hits	169	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

SKIL_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.059448 (rank : 433)
Query Neighborhood Hits	319	Target Neighborhood Hits	719	Shared Neighborhood Hits	90
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SLAP1_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.128099 (rank : 184)
Query Neighborhood Hits	319	Target Neighborhood Hits	113	Shared Neighborhood Hits	41
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

SLAP1_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.125384 (rank : 186)
Query Neighborhood Hits	319	Target Neighborhood Hits	117	Shared Neighborhood Hits	40
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

SLAP2_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.140761 (rank : 174)
Query Neighborhood Hits	319	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.139658 (rank : 175)
Query Neighborhood Hits	319	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SM1L2_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.052872 (rank : 543)
Query Neighborhood Hits	319	Target Neighborhood Hits	1019	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SM1L2_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.050052 (rank : 590)
Query Neighborhood Hits	319	Target Neighborhood Hits	918	Shared Neighborhood Hits	96
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMC1A_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.059553 (rank : 432)
Query Neighborhood Hits	319	Target Neighborhood Hits	1346	Shared Neighborhood Hits	118
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.060204 (rank : 424)
Query Neighborhood Hits	319	Target Neighborhood Hits	1384	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.056811 (rank : 475)
Query Neighborhood Hits	319	Target Neighborhood Hits	1405	Shared Neighborhood Hits	123
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC3_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.051259 (rank : 566)
Query Neighborhood Hits	319	Target Neighborhood Hits	1186	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.051179 (rank : 568)
Query Neighborhood Hits	319	Target Neighborhood Hits	1187	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SPN90_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.157723 (rank : 159)
Query Neighborhood Hits	319	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPN90_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.135009 (rank : 181)
Query Neighborhood Hits	319	Target Neighborhood Hits	157	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SRMS_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.064449 (rank : 381)
Query Neighborhood Hits	319	Target Neighborhood Hits	946	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.071736 (rank : 308)
Query Neighborhood Hits	319	Target Neighborhood Hits	964	Shared Neighborhood Hits	100
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SYCP1_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.054697 (rank : 516)
Query Neighborhood Hits	319	Target Neighborhood Hits	1313	Shared Neighborhood Hits	112
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYCP1_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.057284 (rank : 469)
Query Neighborhood Hits	319	Target Neighborhood Hits	1456	Shared Neighborhood Hits	120
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TAXB1_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.053128 (rank : 539)
Query Neighborhood Hits	319	Target Neighborhood Hits	829	Shared Neighborhood Hits	88
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TAXB1_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.053874 (rank : 525)
Query Neighborhood Hits	319	Target Neighborhood Hits	886	Shared Neighborhood Hits	96
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TEC_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.090398 (rank : 248)
Query Neighborhood Hits	319	Target Neighborhood Hits	1006	Shared Neighborhood Hits	133
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEX14_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.052462 (rank : 552)
Query Neighborhood Hits	319	Target Neighborhood Hits	1333	Shared Neighborhood Hits	97
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX9_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.053795 (rank : 526)
Query Neighborhood Hits	319	Target Neighborhood Hits	581	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TIAM1_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.106392 (rank : 224)
Query Neighborhood Hits	319	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TIAM1_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.108075 (rank : 220)
Query Neighborhood Hits	319	Target Neighborhood Hits	205	Shared Neighborhood Hits	26
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TMF1_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.053789 (rank : 527)
Query Neighborhood Hits	319	Target Neighborhood Hits	987	Shared Neighborhood Hits	96
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TPR_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.055112 (rank : 511)
Query Neighborhood Hits	319	Target Neighborhood Hits	1921	Shared Neighborhood Hits	127
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRIO_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.060823 (rank : 420)
Query Neighborhood Hits	319	Target Neighborhood Hits	1580	Shared Neighborhood Hits	141
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TRIPB_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.069885 (rank : 324)
Query Neighborhood Hits	319	Target Neighborhood Hits	1587	Shared Neighborhood Hits	129
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TSC1_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.050291 (rank : 583)
Query Neighborhood Hits	319	Target Neighborhood Hits	765	Shared Neighborhood Hits	86
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TUFT1_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.058117 (rank : 455)
Query Neighborhood Hits	319	Target Neighborhood Hits	686	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.055450 (rank : 501)
Query Neighborhood Hits	319	Target Neighborhood Hits	732	Shared Neighborhood Hits	89
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

UACA_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.050692 (rank : 573)
Query Neighborhood Hits	319	Target Neighborhood Hits	1620	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

Hits sorted by NC score

SH3G2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	319	Target Neighborhood Hits	319	Shared Neighborhood Hits	319
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G2_HUMAN
NC score	0.994900 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	319	Target Neighborhood Hits	324	Shared Neighborhood Hits	296
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G3_HUMAN
NC score	0.975661 (rank : 3)	θ value	2.51683e-135 (rank : 5)
Query Neighborhood Hits	319	Target Neighborhood Hits	222	Shared Neighborhood Hits	198
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G1_MOUSE
NC score	0.975493 (rank : 4)	θ value	2.42647e-146 (rank : 3)
Query Neighborhood Hits	319	Target Neighborhood Hits	291	Shared Neighborhood Hits	228
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G3_MOUSE
NC score	0.974074 (rank : 5)	θ value	4.9119e-131 (rank : 6)
Query Neighborhood Hits	319	Target Neighborhood Hits	236	Shared Neighborhood Hits	208
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3G1_HUMAN
NC score	0.969228 (rank : 6)	θ value	2.05413e-145 (rank : 4)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	223
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SHLB1_MOUSE
NC score	0.674736 (rank : 7)	θ value	5.23862e-24 (rank : 8)
Query Neighborhood Hits	319	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SHLB1_HUMAN
NC score	0.671065 (rank : 8)	θ value	5.23862e-24 (rank : 7)
Query Neighborhood Hits	319	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SH3K1_HUMAN
NC score	0.652703 (rank : 9)	θ value	1.25267e-09 (rank : 12)
Query Neighborhood Hits	319	Target Neighborhood Hits	341	Shared Neighborhood Hits	208
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
NC score	0.652639 (rank : 10)	θ value	1.47974e-10 (rank : 11)
Query Neighborhood Hits	319	Target Neighborhood Hits	332	Shared Neighborhood Hits	207
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

CD2AP_MOUSE
NC score	0.641266 (rank : 11)	θ value	1.53129e-07 (rank : 28)
Query Neighborhood Hits	319	Target Neighborhood Hits	336	Shared Neighborhood Hits	201
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2AP_HUMAN
NC score	0.636530 (rank : 12)	θ value	6.87365e-08 (rank : 22)
Query Neighborhood Hits	319	Target Neighborhood Hits	315	Shared Neighborhood Hits	199
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

VINEX_HUMAN
NC score	0.630953 (rank : 13)	θ value	1.06045e-08 (rank : 15)
Query Neighborhood Hits	319	Target Neighborhood Hits	270	Shared Neighborhood Hits	193
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
NC score	0.630411 (rank : 14)	θ value	3.08544e-08 (rank : 16)
Query Neighborhood Hits	319	Target Neighborhood Hits	286	Shared Neighborhood Hits	190
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SHLB2_MOUSE
NC score	0.624066 (rank : 15)	θ value	2.5182e-18 (rank : 10)
Query Neighborhood Hits	319	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_HUMAN
NC score	0.622489 (rank : 16)	θ value	6.62687e-19 (rank : 9)
Query Neighborhood Hits	319	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

NCF4_MOUSE
NC score	0.614934 (rank : 17)	θ value	1.99992e-07 (rank : 32)
Query Neighborhood Hits	319	Target Neighborhood Hits	177	Shared Neighborhood Hits	147
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SRBS1_HUMAN
NC score	0.614049 (rank : 18)	θ value	4.0297e-08 (rank : 17)
Query Neighborhood Hits	319	Target Neighborhood Hits	396	Shared Neighborhood Hits	199
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
NC score	0.609712 (rank : 19)	θ value	5.26297e-08 (rank : 21)
Query Neighborhood Hits	319	Target Neighborhood Hits	409	Shared Neighborhood Hits	198
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

HCLS1_MOUSE
NC score	0.609090 (rank : 20)	θ value	8.97725e-08 (rank : 24)
Query Neighborhood Hits	319	Target Neighborhood Hits	329	Shared Neighborhood Hits	168
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HCLS1_HUMAN
NC score	0.607874 (rank : 21)	θ value	6.87365e-08 (rank : 23)
Query Neighborhood Hits	319	Target Neighborhood Hits	358	Shared Neighborhood Hits	164
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

NCF4_HUMAN
NC score	0.604371 (rank : 22)	θ value	1.17247e-07 (rank : 26)
Query Neighborhood Hits	319	Target Neighborhood Hits	161	Shared Neighborhood Hits	131
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SRC8_MOUSE
NC score	0.599383 (rank : 23)	θ value	1.99992e-07 (rank : 33)
Query Neighborhood Hits	319	Target Neighborhood Hits	292	Shared Neighborhood Hits	179
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRC8_HUMAN
NC score	0.599302 (rank : 24)	θ value	1.29631e-06 (rank : 46)
Query Neighborhood Hits	319	Target Neighborhood Hits	269	Shared Neighborhood Hits	178
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

ABI2_MOUSE
NC score	0.596337 (rank : 25)	θ value	5.26297e-08 (rank : 19)
Query Neighborhood Hits	319	Target Neighborhood Hits	266	Shared Neighborhood Hits	175
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

NCF2_HUMAN
NC score	0.593526 (rank : 26)	θ value	0.000270298 (rank : 88)
Query Neighborhood Hits	319	Target Neighborhood Hits	229	Shared Neighborhood Hits	164
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

ABI2_HUMAN
NC score	0.589540 (rank : 27)	θ value	5.26297e-08 (rank : 18)
Query Neighborhood Hits	319	Target Neighborhood Hits	350	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI1_MOUSE
NC score	0.568965 (rank : 28)	θ value	2.21117e-06 (rank : 48)
Query Neighborhood Hits	319	Target Neighborhood Hits	246	Shared Neighborhood Hits	163
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

STAM1_HUMAN
NC score	0.561116 (rank : 29)	θ value	4.45536e-07 (rank : 38)
Query Neighborhood Hits	319	Target Neighborhood Hits	271	Shared Neighborhood Hits	186
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
NC score	0.557666 (rank : 30)	θ value	5.81887e-07 (rank : 40)
Query Neighborhood Hits	319	Target Neighborhood Hits	273	Shared Neighborhood Hits	182
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
NC score	0.553753 (rank : 31)	θ value	2.61198e-07 (rank : 34)
Query Neighborhood Hits	319	Target Neighborhood Hits	285	Shared Neighborhood Hits	186
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

ABI1_HUMAN
NC score	0.552264 (rank : 32)	θ value	3.77169e-06 (rank : 53)
Query Neighborhood Hits	319	Target Neighborhood Hits	257	Shared Neighborhood Hits	163
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

STAC_HUMAN
NC score	0.549070 (rank : 33)	θ value	1.17247e-07 (rank : 27)
Query Neighborhood Hits	319	Target Neighborhood Hits	276	Shared Neighborhood Hits	175
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

GRB2_HUMAN
NC score	0.546331 (rank : 34)	θ value	1.63604e-09 (rank : 13)
Query Neighborhood Hits	319	Target Neighborhood Hits	310	Shared Neighborhood Hits	190
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.545634 (rank : 35)	θ value	1.63604e-09 (rank : 14)
Query Neighborhood Hits	319	Target Neighborhood Hits	312	Shared Neighborhood Hits	190
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRAP2_MOUSE
NC score	0.535275 (rank : 36)	θ value	1.29631e-06 (rank : 45)
Query Neighborhood Hits	319	Target Neighborhood Hits	297	Shared Neighborhood Hits	186
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

DBNL_HUMAN
NC score	0.534639 (rank : 37)	θ value	1.43324e-05 (rank : 65)
Query Neighborhood Hits	319	Target Neighborhood Hits	244	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

STAM2_HUMAN
NC score	0.528584 (rank : 38)	θ value	2.21117e-06 (rank : 51)
Query Neighborhood Hits	319	Target Neighborhood Hits	288	Shared Neighborhood Hits	186
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

DBNL_MOUSE
NC score	0.528445 (rank : 39)	θ value	1.43324e-05 (rank : 66)
Query Neighborhood Hits	319	Target Neighborhood Hits	306	Shared Neighborhood Hits	154
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

GRAP2_HUMAN
NC score	0.527895 (rank : 40)	θ value	1.29631e-06 (rank : 44)
Query Neighborhood Hits	319	Target Neighborhood Hits	304	Shared Neighborhood Hits	186
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

STAC_MOUSE
NC score	0.524769 (rank : 41)	θ value	4.1701e-05 (rank : 77)
Query Neighborhood Hits	319	Target Neighborhood Hits	268	Shared Neighborhood Hits	170
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

ABI3_HUMAN
NC score	0.523129 (rank : 42)	θ value	3.77169e-06 (rank : 54)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	137
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

PACN2_HUMAN
NC score	0.518556 (rank : 43)	θ value	2.44474e-05 (rank : 74)
Query Neighborhood Hits	319	Target Neighborhood Hits	339	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PPIP1_MOUSE
NC score	0.512934 (rank : 44)	θ value	0.00134147 (rank : 108)
Query Neighborhood Hits	319	Target Neighborhood Hits	377	Shared Neighborhood Hits	208
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

PACN2_MOUSE
NC score	0.511275 (rank : 45)	θ value	4.1701e-05 (rank : 76)
Query Neighborhood Hits	319	Target Neighborhood Hits	382	Shared Neighborhood Hits	199
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PPIP1_HUMAN
NC score	0.509144 (rank : 46)	θ value	0.00175202 (rank : 112)
Query Neighborhood Hits	319	Target Neighborhood Hits	389	Shared Neighborhood Hits	208
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

ABI3_MOUSE
NC score	0.507493 (rank : 47)	θ value	2.44474e-05 (rank : 72)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

PACN1_HUMAN
NC score	0.506673 (rank : 48)	θ value	1.69304e-06 (rank : 47)
Query Neighborhood Hits	319	Target Neighborhood Hits	320	Shared Neighborhood Hits	186
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
NC score	0.505206 (rank : 49)	θ value	2.21117e-06 (rank : 50)
Query Neighborhood Hits	319	Target Neighborhood Hits	283	Shared Neighborhood Hits	181
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

ARHG7_MOUSE
NC score	0.505162 (rank : 50)	θ value	3.77169e-06 (rank : 55)
Query Neighborhood Hits	319	Target Neighborhood Hits	396	Shared Neighborhood Hits	209
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG7_HUMAN
NC score	0.501387 (rank : 51)	θ value	4.45536e-07 (rank : 36)
Query Neighborhood Hits	319	Target Neighborhood Hits	347	Shared Neighborhood Hits	195
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

DNMBP_HUMAN
NC score	0.500785 (rank : 52)	θ value	2.88788e-06 (rank : 52)
Query Neighborhood Hits	319	Target Neighborhood Hits	413	Shared Neighborhood Hits	196
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

GRAP_MOUSE
NC score	0.497463 (rank : 53)	θ value	1.87187e-05 (rank : 70)
Query Neighborhood Hits	319	Target Neighborhood Hits	309	Shared Neighborhood Hits	192
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

LASP1_HUMAN
NC score	0.493683 (rank : 54)	θ value	2.44474e-05 (rank : 73)
Query Neighborhood Hits	319	Target Neighborhood Hits	293	Shared Neighborhood Hits	149
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
NC score	0.492938 (rank : 55)	θ value	1.09739e-05 (rank : 60)
Query Neighborhood Hits	319	Target Neighborhood Hits	297	Shared Neighborhood Hits	148
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

DNMBP_MOUSE
NC score	0.491126 (rank : 56)	θ value	3.77169e-06 (rank : 56)
Query Neighborhood Hits	319	Target Neighborhood Hits	435	Shared Neighborhood Hits	195
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

GRAP_HUMAN
NC score	0.490032 (rank : 57)	θ value	1.87187e-05 (rank : 69)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	190
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

ARHG6_MOUSE
NC score	0.489096 (rank : 58)	θ value	6.43352e-06 (rank : 57)
Query Neighborhood Hits	319	Target Neighborhood Hits	394	Shared Neighborhood Hits	202
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG6_HUMAN
NC score	0.482442 (rank : 59)	θ value	2.21117e-06 (rank : 49)
Query Neighborhood Hits	319	Target Neighborhood Hits	376	Shared Neighborhood Hits	202
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

CT032_HUMAN
NC score	0.473332 (rank : 60)	θ value	8.40245e-06 (rank : 59)
Query Neighborhood Hits	319	Target Neighborhood Hits	235	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

OSTF1_HUMAN
NC score	0.472181 (rank : 61)	θ value	5.26297e-08 (rank : 20)
Query Neighborhood Hits	319	Target Neighborhood Hits	466	Shared Neighborhood Hits	186
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PACN3_MOUSE
NC score	0.463926 (rank : 62)	θ value	0.00228821 (rank : 117)
Query Neighborhood Hits	319	Target Neighborhood Hits	380	Shared Neighborhood Hits	197
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

NEBL_HUMAN
NC score	0.463409 (rank : 63)	θ value	3.19293e-05 (rank : 75)
Query Neighborhood Hits	319	Target Neighborhood Hits	457	Shared Neighborhood Hits	192
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

PACN3_HUMAN
NC score	0.461963 (rank : 64)	θ value	0.00228821 (rank : 116)
Query Neighborhood Hits	319	Target Neighborhood Hits	385	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

OSTF1_MOUSE
NC score	0.458364 (rank : 65)	θ value	1.53129e-07 (rank : 30)
Query Neighborhood Hits	319	Target Neighborhood Hits	467	Shared Neighborhood Hits	186
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

CRKL_HUMAN
NC score	0.453462 (rank : 66)	θ value	0.000602161 (rank : 92)
Query Neighborhood Hits	319	Target Neighborhood Hits	313	Shared Neighborhood Hits	182
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

NCK2_HUMAN
NC score	0.453238 (rank : 67)	θ value	0.00509761 (rank : 125)
Query Neighborhood Hits	319	Target Neighborhood Hits	310	Shared Neighborhood Hits	183
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

SNX18_MOUSE
NC score	0.453148 (rank : 68)	θ value	1.09739e-05 (rank : 61)
Query Neighborhood Hits	319	Target Neighborhood Hits	198	Shared Neighborhood Hits	131
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

CRK_MOUSE
NC score	0.450736 (rank : 69)	θ value	0.00134147 (rank : 105)
Query Neighborhood Hits	319	Target Neighborhood Hits	314	Shared Neighborhood Hits	186
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

NCK1_HUMAN
NC score	0.449439 (rank : 70)	θ value	0.0431538 (rank : 145)
Query Neighborhood Hits	319	Target Neighborhood Hits	312	Shared Neighborhood Hits	186
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

CRKL_MOUSE
NC score	0.447750 (rank : 71)	θ value	0.00102713 (rank : 102)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	181
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

SNX18_HUMAN
NC score	0.445514 (rank : 72)	θ value	1.43324e-05 (rank : 67)
Query Neighborhood Hits	319	Target Neighborhood Hits	207	Shared Neighborhood Hits	132
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

CRK_HUMAN
NC score	0.444709 (rank : 73)	θ value	0.00134147 (rank : 104)
Query Neighborhood Hits	319	Target Neighborhood Hits	308	Shared Neighborhood Hits	186
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

STAC3_MOUSE
NC score	0.437085 (rank : 74)	θ value	0.0148317 (rank : 134)
Query Neighborhood Hits	319	Target Neighborhood Hits	232	Shared Neighborhood Hits	143
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_HUMAN
NC score	0.433539 (rank : 75)	θ value	0.0113563 (rank : 133)
Query Neighborhood Hits	319	Target Neighborhood Hits	228	Shared Neighborhood Hits	141
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

NCF1_HUMAN
NC score	0.422812 (rank : 76)	θ value	0.365318 (rank : 184)
Query Neighborhood Hits	319	Target Neighborhood Hits	198	Shared Neighborhood Hits	149
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

VAV_MOUSE
NC score	0.420625 (rank : 77)	θ value	1.43324e-05 (rank : 68)
Query Neighborhood Hits	319	Target Neighborhood Hits	430	Shared Neighborhood Hits	190
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

ITSN2_HUMAN
NC score	0.418087 (rank : 78)	θ value	1.99992e-07 (rank : 31)
Query Neighborhood Hits	319	Target Neighborhood Hits	1173	Shared Neighborhood Hits	270
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

VAV_HUMAN
NC score	0.416786 (rank : 79)	θ value	1.87187e-05 (rank : 71)
Query Neighborhood Hits	319	Target Neighborhood Hits	452	Shared Neighborhood Hits	188
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

NCF1_MOUSE
NC score	0.411250 (rank : 80)	θ value	1.81305 (rank : 233)
Query Neighborhood Hits	319	Target Neighborhood Hits	198	Shared Neighborhood Hits	162
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

CASL_MOUSE
NC score	0.406190 (rank : 81)	θ value	1.43324e-05 (rank : 64)
Query Neighborhood Hits	319	Target Neighborhood Hits	225	Shared Neighborhood Hits	145
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CASL_HUMAN
NC score	0.405509 (rank : 82)	θ value	1.43324e-05 (rank : 63)
Query Neighborhood Hits	319	Target Neighborhood Hits	259	Shared Neighborhood Hits	149
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

ITSN1_MOUSE
NC score	0.403621 (rank : 83)	θ value	3.41135e-07 (rank : 35)
Query Neighborhood Hits	319	Target Neighborhood Hits	1669	Shared Neighborhood Hits	292
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.403144 (rank : 84)	θ value	1.17247e-07 (rank : 25)
Query Neighborhood Hits	319	Target Neighborhood Hits	1757	Shared Neighborhood Hits	297
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

BCAR1_MOUSE
NC score	0.401984 (rank : 85)	θ value	0.000786445 (rank : 97)
Query Neighborhood Hits	319	Target Neighborhood Hits	438	Shared Neighborhood Hits	161
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_HUMAN
NC score	0.397953 (rank : 86)	θ value	0.000270298 (rank : 85)
Query Neighborhood Hits	319	Target Neighborhood Hits	554	Shared Neighborhood Hits	166
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

ITSN2_MOUSE
NC score	0.397396 (rank : 87)	θ value	5.81887e-07 (rank : 39)
Query Neighborhood Hits	319	Target Neighborhood Hits	1371	Shared Neighborhood Hits	284
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

EFS_MOUSE
NC score	0.395338 (rank : 88)	θ value	0.00134147 (rank : 107)
Query Neighborhood Hits	319	Target Neighborhood Hits	389	Shared Neighborhood Hits	154
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

AHI1_MOUSE
NC score	0.390928 (rank : 89)	θ value	8.40245e-06 (rank : 58)
Query Neighborhood Hits	319	Target Neighborhood Hits	496	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

EFS_HUMAN
NC score	0.388179 (rank : 90)	θ value	0.00134147 (rank : 106)
Query Neighborhood Hits	319	Target Neighborhood Hits	348	Shared Neighborhood Hits	149
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

RIMB2_HUMAN
NC score	0.387226 (rank : 91)	θ value	9.29e-05 (rank : 78)
Query Neighborhood Hits	319	Target Neighborhood Hits	263	Shared Neighborhood Hits	126
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
NC score	0.385642 (rank : 92)	θ value	0.000121331 (rank : 80)
Query Neighborhood Hits	319	Target Neighborhood Hits	246	Shared Neighborhood Hits	125
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

VAV2_MOUSE
NC score	0.382464 (rank : 93)	θ value	0.00175202 (rank : 115)
Query Neighborhood Hits	319	Target Neighborhood Hits	456	Shared Neighborhood Hits	176
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

AHI1_HUMAN
NC score	0.382271 (rank : 94)	θ value	1.43324e-05 (rank : 62)
Query Neighborhood Hits	319	Target Neighborhood Hits	537	Shared Neighborhood Hits	179
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

VAV2_HUMAN
NC score	0.380486 (rank : 95)	θ value	0.00175202 (rank : 114)
Query Neighborhood Hits	319	Target Neighborhood Hits	453	Shared Neighborhood Hits	176
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

NPHP1_MOUSE
NC score	0.378934 (rank : 96)	θ value	0.0736092 (rank : 154)
Query Neighborhood Hits	319	Target Neighborhood Hits	267	Shared Neighborhood Hits	184
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

NEBU_HUMAN
NC score	0.378476 (rank : 97)	θ value	0.000121331 (rank : 79)
Query Neighborhood Hits	319	Target Neighborhood Hits	420	Shared Neighborhood Hits	171
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

PEX13_HUMAN
NC score	0.356200 (rank : 98)	θ value	0.0431538 (rank : 146)
Query Neighborhood Hits	319	Target Neighborhood Hits	128	Shared Neighborhood Hits	106
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
NC score	0.352756 (rank : 99)	θ value	0.125558 (rank : 165)
Query Neighborhood Hits	319	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

ARHG4_HUMAN
NC score	0.350528 (rank : 100)	θ value	0.00175202 (rank : 111)
Query Neighborhood Hits	319	Target Neighborhood Hits	242	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

VAV3_HUMAN
NC score	0.349765 (rank : 101)	θ value	0.0330416 (rank : 142)
Query Neighborhood Hits	319	Target Neighborhood Hits	398	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
NC score	0.344822 (rank : 102)	θ value	0.0148317 (rank : 135)
Query Neighborhood Hits	319	Target Neighborhood Hits	404	Shared Neighborhood Hits	171
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ARHG9_HUMAN
NC score	0.331576 (rank : 103)	θ value	0.00665767 (rank : 127)
Query Neighborhood Hits	319	Target Neighborhood Hits	235	Shared Neighborhood Hits	154
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
NC score	0.331393 (rank : 104)	θ value	0.00665767 (rank : 128)
Query Neighborhood Hits	319	Target Neighborhood Hits	234	Shared Neighborhood Hits	154
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

SNX9_HUMAN
NC score	0.328244 (rank : 105)	θ value	0.00134147 (rank : 110)
Query Neighborhood Hits	319	Target Neighborhood Hits	148	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

RUSC1_HUMAN
NC score	0.328121 (rank : 106)	θ value	0.0736092 (rank : 155)
Query Neighborhood Hits	319	Target Neighborhood Hits	226	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

PLCG1_MOUSE
NC score	0.320665 (rank : 107)	θ value	0.0431538 (rank : 147)
Query Neighborhood Hits	319	Target Neighborhood Hits	314	Shared Neighborhood Hits	153
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
NC score	0.311121 (rank : 108)	θ value	0.365318 (rank : 185)
Query Neighborhood Hits	319	Target Neighborhood Hits	280	Shared Neighborhood Hits	149
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

NPHP1_HUMAN
NC score	0.309149 (rank : 109)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	319	Target Neighborhood Hits	288	Shared Neighborhood Hits	166
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

RUSC1_MOUSE
NC score	0.308993 (rank : 110)	θ value	0.125558 (rank : 167)
Query Neighborhood Hits	319	Target Neighborhood Hits	206	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SNX9_MOUSE
NC score	0.307592 (rank : 111)	θ value	0.00390308 (rank : 122)
Query Neighborhood Hits	319	Target Neighborhood Hits	141	Shared Neighborhood Hits	92
SwissProt Accessions	Q91VH2	Gene names	Snx9
Domain Architecture
Description	Sorting nexin-9.

DDEF1_MOUSE
NC score	0.304290 (rank : 112)	θ value	9.92553e-07 (rank : 42)
Query Neighborhood Hits	319	Target Neighborhood Hits	592	Shared Neighborhood Hits	154
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

PLCG1_HUMAN
NC score	0.301756 (rank : 113)	θ value	0.163984 (rank : 172)
Query Neighborhood Hits	319	Target Neighborhood Hits	293	Shared Neighborhood Hits	147
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

RHG26_HUMAN
NC score	0.292269 (rank : 114)	θ value	0.000786445 (rank : 100)
Query Neighborhood Hits	319	Target Neighborhood Hits	281	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

IASPP_HUMAN
NC score	0.292007 (rank : 115)	θ value	0.00390308 (rank : 121)
Query Neighborhood Hits	319	Target Neighborhood Hits	688	Shared Neighborhood Hits	153
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ASPP1_MOUSE
NC score	0.282586 (rank : 116)	θ value	0.00134147 (rank : 103)
Query Neighborhood Hits	319	Target Neighborhood Hits	1244	Shared Neighborhood Hits	215
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_HUMAN
NC score	0.279525 (rank : 117)	θ value	0.00665767 (rank : 129)
Query Neighborhood Hits	319	Target Neighborhood Hits	956	Shared Neighborhood Hits	205
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ARHG4_MOUSE
NC score	0.278019 (rank : 118)	θ value	0.163984 (rank : 168)
Query Neighborhood Hits	319	Target Neighborhood Hits	185	Shared Neighborhood Hits	113
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

MYO1F_HUMAN
NC score	0.276568 (rank : 119)	θ value	1.53129e-07 (rank : 29)
Query Neighborhood Hits	319	Target Neighborhood Hits	275	Shared Neighborhood Hits	196
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
NC score	0.273963 (rank : 120)	θ value	7.59969e-07 (rank : 41)
Query Neighborhood Hits	319	Target Neighborhood Hits	262	Shared Neighborhood Hits	195
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

DDEF2_MOUSE
NC score	0.272267 (rank : 121)	θ value	0.000270298 (rank : 87)
Query Neighborhood Hits	319	Target Neighborhood Hits	625	Shared Neighborhood Hits	159
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

RHG04_HUMAN
NC score	0.271921 (rank : 122)	θ value	0.279714 (rank : 180)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	165
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

DDEF2_HUMAN
NC score	0.268206 (rank : 123)	θ value	0.000158464 (rank : 81)
Query Neighborhood Hits	319	Target Neighborhood Hits	599	Shared Neighborhood Hits	159
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

IASPP_MOUSE
NC score	0.266446 (rank : 124)	θ value	0.00509761 (rank : 123)
Query Neighborhood Hits	319	Target Neighborhood Hits	1024	Shared Neighborhood Hits	161
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MYO1E_HUMAN
NC score	0.266068 (rank : 125)	θ value	4.45536e-07 (rank : 37)
Query Neighborhood Hits	319	Target Neighborhood Hits	293	Shared Neighborhood Hits	193
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

ES8L3_MOUSE
NC score	0.266052 (rank : 126)	θ value	0.62314 (rank : 197)
Query Neighborhood Hits	319	Target Neighborhood Hits	168	Shared Neighborhood Hits	130
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

SRGP2_MOUSE
NC score	0.261909 (rank : 127)	θ value	0.0431538 (rank : 150)
Query Neighborhood Hits	319	Target Neighborhood Hits	324	Shared Neighborhood Hits	170
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SPTA2_HUMAN
NC score	0.260392 (rank : 128)	θ value	0.00020696 (rank : 83)
Query Neighborhood Hits	319	Target Neighborhood Hits	888	Shared Neighborhood Hits	234
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRGP2_HUMAN
NC score	0.258030 (rank : 129)	θ value	0.0431538 (rank : 149)
Query Neighborhood Hits	319	Target Neighborhood Hits	331	Shared Neighborhood Hits	165
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RIMB1_HUMAN
NC score	0.253860 (rank : 130)	θ value	0.00035302 (rank : 90)
Query Neighborhood Hits	319	Target Neighborhood Hits	1479	Shared Neighborhood Hits	226
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ASPP2_HUMAN
NC score	0.250186 (rank : 131)	θ value	0.000461057 (rank : 91)
Query Neighborhood Hits	319	Target Neighborhood Hits	1156	Shared Neighborhood Hits	206
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

SPTA1_MOUSE
NC score	0.249519 (rank : 132)	θ value	0.00228821 (rank : 118)
Query Neighborhood Hits	319	Target Neighborhood Hits	675	Shared Neighborhood Hits	202
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SRGP1_HUMAN
NC score	0.241507 (rank : 133)	θ value	0.0961366 (rank : 162)
Query Neighborhood Hits	319	Target Neighborhood Hits	390	Shared Neighborhood Hits	164
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RIMB1_MOUSE
NC score	0.240937 (rank : 134)	θ value	0.00134147 (rank : 109)
Query Neighborhood Hits	319	Target Neighborhood Hits	1376	Shared Neighborhood Hits	244
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

FNBP2_HUMAN
NC score	0.240441 (rank : 135)	θ value	0.163984 (rank : 170)
Query Neighborhood Hits	319	Target Neighborhood Hits	432	Shared Neighborhood Hits	174
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

ES8L3_HUMAN
NC score	0.239469 (rank : 136)	θ value	0.21417 (rank : 174)
Query Neighborhood Hits	319	Target Neighborhood Hits	206	Shared Neighborhood Hits	119
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

SPTA1_HUMAN
NC score	0.238389 (rank : 137)	θ value	0.0113563 (rank : 132)
Query Neighborhood Hits	319	Target Neighborhood Hits	748	Shared Neighborhood Hits	222
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

ARHG5_HUMAN
NC score	0.230762 (rank : 138)	θ value	0.00298849 (rank : 119)
Query Neighborhood Hits	319	Target Neighborhood Hits	172	Shared Neighborhood Hits	89
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ANM2_HUMAN
NC score	0.229283 (rank : 139)	θ value	1.38821 (rank : 213)
Query Neighborhood Hits	319	Target Neighborhood Hits	175	Shared Neighborhood Hits	141
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

NOXO1_MOUSE
NC score	0.221987 (rank : 140)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	319	Target Neighborhood Hits	114	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

ANM2_MOUSE
NC score	0.216883 (rank : 141)	θ value	3.0926 (rank : 250)
Query Neighborhood Hits	319	Target Neighborhood Hits	175	Shared Neighborhood Hits	139
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

SHAN2_MOUSE
NC score	0.212386 (rank : 142)	θ value	0.0113563 (rank : 131)
Query Neighborhood Hits	319	Target Neighborhood Hits	446	Shared Neighborhood Hits	107
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

STS2_HUMAN
NC score	0.205371 (rank : 143)	θ value	0.365318 (rank : 187)
Query Neighborhood Hits	319	Target Neighborhood Hits	108	Shared Neighborhood Hits	81
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

ES8L2_HUMAN
NC score	0.196603 (rank : 144)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	319	Target Neighborhood Hits	193	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
NC score	0.194837 (rank : 145)	θ value	0.813845 (rank : 203)
Query Neighborhood Hits	319	Target Neighborhood Hits	169	Shared Neighborhood Hits	116
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

EPS8_HUMAN
NC score	0.193490 (rank : 146)	θ value	2.36792 (rank : 238)
Query Neighborhood Hits	319	Target Neighborhood Hits	151	Shared Neighborhood Hits	100
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

EPS8_MOUSE
NC score	0.189677 (rank : 147)	θ value	2.36792 (rank : 239)
Query Neighborhood Hits	319	Target Neighborhood Hits	157	Shared Neighborhood Hits	117
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

TCGAP_MOUSE
NC score	0.189029 (rank : 148)	θ value	0.47712 (rank : 193)
Query Neighborhood Hits	319	Target Neighborhood Hits	409	Shared Neighborhood Hits	124
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

EM55_HUMAN
NC score	0.179685 (rank : 149)	θ value	0.0431538 (rank : 143)
Query Neighborhood Hits	319	Target Neighborhood Hits	228	Shared Neighborhood Hits	96
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.176468 (rank : 150)	θ value	0.0431538 (rank : 144)
Query Neighborhood Hits	319	Target Neighborhood Hits	221	Shared Neighborhood Hits	92
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

SLY_MOUSE
NC score	0.174163 (rank : 151)	θ value	0.0736092 (rank : 157)
Query Neighborhood Hits	319	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

STS1_MOUSE
NC score	0.172728 (rank : 152)	θ value	3.0926 (rank : 262)
Query Neighborhood Hits	319	Target Neighborhood Hits	104	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BGG7, Q3U8Z2, Q8BMW9	Gene names	Sts1
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

STS1_HUMAN
NC score	0.170512 (rank : 153)	θ value	4.03905 (rank : 278)
Query Neighborhood Hits	319	Target Neighborhood Hits	106	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TF42, Q53GT5, Q53GT8, Q8NBV7, Q96IG9, Q96NZ2	Gene names	STS1, KIAA1959
Domain Architecture	No domain graphic available
Description	Suppressor of T-cell receptor signaling 1 (Sts-1) (Cbl-interacting protein p70).

TCGAP_HUMAN
NC score	0.169524 (rank : 154)	θ value	0.47712 (rank : 192)
Query Neighborhood Hits	319	Target Neighborhood Hits	872	Shared Neighborhood Hits	130
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ES8L1_HUMAN
NC score	0.169464 (rank : 155)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	319	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

CIP4_HUMAN
NC score	0.168718 (rank : 156)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	319	Target Neighborhood Hits	374	Shared Neighborhood Hits	115
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

M3KL4_HUMAN
NC score	0.162487 (rank : 157)	θ value	0.000158464 (rank : 82)
Query Neighborhood Hits	319	Target Neighborhood Hits	1087	Shared Neighborhood Hits	194
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

NOXO1_HUMAN
NC score	0.158542 (rank : 158)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	319	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

SPN90_HUMAN
NC score	0.157723 (rank : 159)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	319	Target Neighborhood Hits	157	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

ES8L1_MOUSE
NC score	0.155609 (rank : 160)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	319	Target Neighborhood Hits	143	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

SLY_HUMAN
NC score	0.155222 (rank : 161)	θ value	0.0961366 (rank : 161)
Query Neighborhood Hits	319	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

FYN_MOUSE
NC score	0.152425 (rank : 162)	θ value	0.000786445 (rank : 99)
Query Neighborhood Hits	319	Target Neighborhood Hits	1073	Shared Neighborhood Hits	181
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

M3K11_HUMAN
NC score	0.151634 (rank : 163)	θ value	9.92553e-07 (rank : 43)
Query Neighborhood Hits	319	Target Neighborhood Hits	1136	Shared Neighborhood Hits	177
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

AMPH_HUMAN
NC score	0.150445 (rank : 164)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	319	Target Neighborhood Hits	455	Shared Neighborhood Hits	102
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

FYN_HUMAN
NC score	0.149734 (rank : 165)	θ value	0.000786445 (rank : 98)
Query Neighborhood Hits	319	Target Neighborhood Hits	1078	Shared Neighborhood Hits	181
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

YES_MOUSE
NC score	0.147152 (rank : 166)	θ value	0.000786445 (rank : 101)
Query Neighborhood Hits	319	Target Neighborhood Hits	1052	Shared Neighborhood Hits	176
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

SHAN1_HUMAN
NC score	0.146861 (rank : 167)	θ value	0.0736092 (rank : 156)
Query Neighborhood Hits	319	Target Neighborhood Hits	1041	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SRC_HUMAN
NC score	0.146587 (rank : 168)	θ value	0.000602161 (rank : 95)
Query Neighborhood Hits	319	Target Neighborhood Hits	1058	Shared Neighborhood Hits	178
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

FGR_HUMAN
NC score	0.145863 (rank : 169)	θ value	0.0193708 (rank : 136)
Query Neighborhood Hits	319	Target Neighborhood Hits	1067	Shared Neighborhood Hits	174
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

NGEF_HUMAN
NC score	0.145681 (rank : 170)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	319	Target Neighborhood Hits	166	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

P85A_MOUSE
NC score	0.145550 (rank : 171)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	319	Target Neighborhood Hits	435	Shared Neighborhood Hits	127
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

YES_HUMAN
NC score	0.144810 (rank : 172)	θ value	0.00298849 (rank : 120)
Query Neighborhood Hits	319	Target Neighborhood Hits	1059	Shared Neighborhood Hits	174
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

NGEF_MOUSE
NC score	0.143936 (rank : 173)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	319	Target Neighborhood Hits	228	Shared Neighborhood Hits	87
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

SLAP2_HUMAN
NC score	0.140761 (rank : 174)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	319	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H6Q3, Q5TH27, Q5TH28, Q8WY18, Q96QI4, Q9H135	Gene names	SLA2, C20orf156, SLAP2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) (Modulator of antigen receptor signaling) (MARS).

SLAP2_MOUSE
NC score	0.139658 (rank : 175)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	319	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

BAIP2_MOUSE
NC score	0.139590 (rank : 176)	θ value	2.36792 (rank : 236)
Query Neighborhood Hits	319	Target Neighborhood Hits	185	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

FGR_MOUSE
NC score	0.139213 (rank : 177)	θ value	0.0961366 (rank : 159)
Query Neighborhood Hits	319	Target Neighborhood Hits	1069	Shared Neighborhood Hits	173
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

BAIP2_HUMAN
NC score	0.137374 (rank : 178)	θ value	2.36792 (rank : 235)
Query Neighborhood Hits	319	Target Neighborhood Hits	192	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

M3K9_HUMAN
NC score	0.136337 (rank : 179)	θ value	0.00509761 (rank : 124)
Query Neighborhood Hits	319	Target Neighborhood Hits	1123	Shared Neighborhood Hits	183
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

P85A_HUMAN
NC score	0.135093 (rank : 180)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	319	Target Neighborhood Hits	479	Shared Neighborhood Hits	135
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SPN90_MOUSE
NC score	0.135009 (rank : 181)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	319	Target Neighborhood Hits	157	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

MPP6_HUMAN
NC score	0.132527 (rank : 182)	θ value	2.36792 (rank : 243)
Query Neighborhood Hits	319	Target Neighborhood Hits	180	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

RUSC2_HUMAN
NC score	0.130545 (rank : 183)	θ value	1.38821 (rank : 221)
Query Neighborhood Hits	319	Target Neighborhood Hits	205	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SLAP1_HUMAN
NC score	0.128099 (rank : 184)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	319	Target Neighborhood Hits	113	Shared Neighborhood Hits	41
SwissProt Accessions	Q13239, Q9UMQ8	Gene names	SLA, SLAP, SLAP1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (hSLAP).

MPP6_MOUSE
NC score	0.126885 (rank : 185)	θ value	2.36792 (rank : 244)
Query Neighborhood Hits	319	Target Neighborhood Hits	187	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

SLAP1_MOUSE
NC score	0.125384 (rank : 186)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	319	Target Neighborhood Hits	117	Shared Neighborhood Hits	40
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

BI2L1_HUMAN
NC score	0.125279 (rank : 187)	θ value	3.0926 (rank : 251)
Query Neighborhood Hits	319	Target Neighborhood Hits	156	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

AMPH_MOUSE
NC score	0.125148 (rank : 188)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	319	Target Neighborhood Hits	291	Shared Neighborhood Hits	89
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

M3K10_HUMAN
NC score	0.124941 (rank : 189)	θ value	0.0330416 (rank : 141)
Query Neighborhood Hits	319	Target Neighborhood Hits	1071	Shared Neighborhood Hits	166
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

BTK_HUMAN
NC score	0.124302 (rank : 190)	θ value	0.163984 (rank : 169)
Query Neighborhood Hits	319	Target Neighborhood Hits	1026	Shared Neighborhood Hits	171
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

ARHGG_MOUSE
NC score	0.123188 (rank : 191)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	319	Target Neighborhood Hits	152	Shared Neighborhood Hits	62
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

HCK_MOUSE
NC score	0.121520 (rank : 192)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	319	Target Neighborhood Hits	1029	Shared Neighborhood Hits	163
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

SRC_MOUSE
NC score	0.121361 (rank : 193)	θ value	0.0431538 (rank : 148)
Query Neighborhood Hits	319	Target Neighborhood Hits	1033	Shared Neighborhood Hits	157
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

DOCK1_HUMAN
NC score	0.120250 (rank : 194)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	319	Target Neighborhood Hits	191	Shared Neighborhood Hits	110
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

HCK_HUMAN
NC score	0.119984 (rank : 195)	θ value	1.81305 (rank : 228)
Query Neighborhood Hits	319	Target Neighborhood Hits	1035	Shared Neighborhood Hits	164
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

PKHG1_HUMAN
NC score	0.118473 (rank : 196)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	319	Target Neighborhood Hits	174	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

BIN1_MOUSE
NC score	0.118247 (rank : 197)	θ value	5.27518 (rank : 279)
Query Neighborhood Hits	319	Target Neighborhood Hits	283	Shared Neighborhood Hits	83
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

GLE1_HUMAN
NC score	0.117328 (rank : 198)	θ value	0.0330416 (rank : 140)
Query Neighborhood Hits	319	Target Neighborhood Hits	445	Shared Neighborhood Hits	75
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

P85B_HUMAN
NC score	0.117155 (rank : 199)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	319	Target Neighborhood Hits	543	Shared Neighborhood Hits	121
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

BTK_MOUSE
NC score	0.117108 (rank : 200)	θ value	0.62314 (rank : 194)
Query Neighborhood Hits	319	Target Neighborhood Hits	1017	Shared Neighborhood Hits	162
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

MPP2_MOUSE
NC score	0.114174 (rank : 201)	θ value	0.62314 (rank : 198)
Query Neighborhood Hits	319	Target Neighborhood Hits	189	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP2_HUMAN
NC score	0.113963 (rank : 202)	θ value	1.38821 (rank : 218)
Query Neighborhood Hits	319	Target Neighborhood Hits	173	Shared Neighborhood Hits	68
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP5_HUMAN
NC score	0.113782 (rank : 203)	θ value	1.81305 (rank : 230)
Query Neighborhood Hits	319	Target Neighborhood Hits	231	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

3BP1_HUMAN
NC score	0.113190 (rank : 204)	θ value	0.000270298 (rank : 84)
Query Neighborhood Hits	319	Target Neighborhood Hits	376	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

PREX1_HUMAN
NC score	0.113159 (rank : 205)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	319	Target Neighborhood Hits	177	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

MPP5_MOUSE
NC score	0.113067 (rank : 206)	θ value	1.81305 (rank : 231)
Query Neighborhood Hits	319	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MCF2L_MOUSE
NC score	0.112684 (rank : 207)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	319	Target Neighborhood Hits	255	Shared Neighborhood Hits	63
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

BIN1_HUMAN
NC score	0.112678 (rank : 208)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	319	Target Neighborhood Hits	335	Shared Neighborhood Hits	81
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

RUSC2_MOUSE
NC score	0.112544 (rank : 209)	θ value	2.36792 (rank : 249)
Query Neighborhood Hits	319	Target Neighborhood Hits	305	Shared Neighborhood Hits	69
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SKI_HUMAN
NC score	0.111859 (rank : 210)	θ value	0.00175202 (rank : 113)
Query Neighborhood Hits	319	Target Neighborhood Hits	423	Shared Neighborhood Hits	68
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

JIP1_HUMAN
NC score	0.111839 (rank : 211)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	319	Target Neighborhood Hits	271	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
NC score	0.111686 (rank : 212)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	319	Target Neighborhood Hits	259	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

P85B_MOUSE
NC score	0.110858 (rank : 213)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	319	Target Neighborhood Hits	519	Shared Neighborhood Hits	121
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SKI_MOUSE
NC score	0.109593 (rank : 214)	θ value	0.00509761 (rank : 126)
Query Neighborhood Hits	319	Target Neighborhood Hits	423	Shared Neighborhood Hits	66
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

TXK_MOUSE
NC score	0.109523 (rank : 215)	θ value	0.000602161 (rank : 96)
Query Neighborhood Hits	319	Target Neighborhood Hits	980	Shared Neighborhood Hits	138
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

FRK_HUMAN
NC score	0.109284 (rank : 216)	θ value	3.0926 (rank : 254)
Query Neighborhood Hits	319	Target Neighborhood Hits	1058	Shared Neighborhood Hits	171
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

LCK_HUMAN
NC score	0.108895 (rank : 217)	θ value	0.000602161 (rank : 93)
Query Neighborhood Hits	319	Target Neighborhood Hits	987	Shared Neighborhood Hits	117
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
NC score	0.108298 (rank : 218)	θ value	0.000602161 (rank : 94)
Query Neighborhood Hits	319	Target Neighborhood Hits	981	Shared Neighborhood Hits	116
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

ARHGG_HUMAN
NC score	0.108168 (rank : 219)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	319	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

TIAM1_MOUSE
NC score	0.108075 (rank : 220)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	319	Target Neighborhood Hits	205	Shared Neighborhood Hits	26
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

RASA1_HUMAN
NC score	0.107605 (rank : 221)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	319	Target Neighborhood Hits	258	Shared Neighborhood Hits	63
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

ARHG3_MOUSE
NC score	0.107118 (rank : 222)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	319	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG3_HUMAN
NC score	0.107080 (rank : 223)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	319	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

TIAM1_HUMAN
NC score	0.106392 (rank : 224)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	319	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

LYN_HUMAN
NC score	0.106286 (rank : 225)	θ value	4.03905 (rank : 275)
Query Neighborhood Hits	319	Target Neighborhood Hits	1022	Shared Neighborhood Hits	148
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

ARHG8_MOUSE
NC score	0.104674 (rank : 226)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	319	Target Neighborhood Hits	79	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

LYN_MOUSE
NC score	0.104308 (rank : 227)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	319	Target Neighborhood Hits	1023	Shared Neighborhood Hits	148
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

BI2L1_MOUSE
NC score	0.103154 (rank : 228)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	319	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CSK_MOUSE
NC score	0.102335 (rank : 229)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	319	Target Neighborhood Hits	1009	Shared Neighborhood Hits	134
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CSK_HUMAN
NC score	0.102097 (rank : 230)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	319	Target Neighborhood Hits	1009	Shared Neighborhood Hits	134
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

SAMN1_MOUSE
NC score	0.100611 (rank : 231)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	319	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

PTK6_MOUSE
NC score	0.099663 (rank : 232)	θ value	4.03905 (rank : 277)
Query Neighborhood Hits	319	Target Neighborhood Hits	1026	Shared Neighborhood Hits	149
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

SAMN1_HUMAN
NC score	0.097925 (rank : 233)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	319	Target Neighborhood Hits	74	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

BLK_HUMAN
NC score	0.097919 (rank : 234)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	319	Target Neighborhood Hits	994	Shared Neighborhood Hits	135
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

GLE1_MOUSE
NC score	0.096404 (rank : 235)	θ value	0.163984 (rank : 171)
Query Neighborhood Hits	319	Target Neighborhood Hits	504	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

PTK6_HUMAN
NC score	0.096075 (rank : 236)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	319	Target Neighborhood Hits	1020	Shared Neighborhood Hits	152
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

ARHG8_HUMAN
NC score	0.095942 (rank : 237)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	319	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

SASH1_HUMAN
NC score	0.095640 (rank : 238)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	319	Target Neighborhood Hits	292	Shared Neighborhood Hits	60
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

CENPQ_HUMAN
NC score	0.095257 (rank : 239)	θ value	0.0563607 (rank : 151)
Query Neighborhood Hits	319	Target Neighborhood Hits	131	Shared Neighborhood Hits	27
SwissProt Accessions	Q7L2Z9, Q6IN61, Q9NVS5	Gene names	CENPQ, C6orf139
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

MCF2_HUMAN
NC score	0.094883 (rank : 240)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	319	Target Neighborhood Hits	166	Shared Neighborhood Hits	35
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

BLK_MOUSE
NC score	0.094809 (rank : 241)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	319	Target Neighborhood Hits	992	Shared Neighborhood Hits	125
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

ARHGA_MOUSE
NC score	0.094640 (rank : 242)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	319	Target Neighborhood Hits	125	Shared Neighborhood Hits	31
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

P55G_HUMAN
NC score	0.094203 (rank : 243)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	319	Target Neighborhood Hits	451	Shared Neighborhood Hits	105
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

TXK_HUMAN
NC score	0.092274 (rank : 244)	θ value	0.365318 (rank : 188)
Query Neighborhood Hits	319	Target Neighborhood Hits	971	Shared Neighborhood Hits	121
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

SH21B_MOUSE
NC score	0.091944 (rank : 245)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	319	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	O35324, Q8C268	Gene names	Sh2d1b, Eat2, Sh2d1b1
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

PPIP2_HUMAN
NC score	0.091657 (rank : 246)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	319	Target Neighborhood Hits	254	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

P55G_MOUSE
NC score	0.090663 (rank : 247)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	319	Target Neighborhood Hits	401	Shared Neighborhood Hits	95
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

TEC_HUMAN
NC score	0.090398 (rank : 248)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	319	Target Neighborhood Hits	1006	Shared Neighborhood Hits	133
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

SASH1_MOUSE
NC score	0.090293 (rank : 249)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	319	Target Neighborhood Hits	263	Shared Neighborhood Hits	57
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

ARHGA_HUMAN
NC score	0.089651 (rank : 250)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	319	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

TEC_MOUSE
NC score	0.089155 (rank : 251)	θ value	1.38821 (rank : 223)
Query Neighborhood Hits	319	Target Neighborhood Hits	1006	Shared Neighborhood Hits	133
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

DAPP1_MOUSE
NC score	0.088548 (rank : 252)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	319	Target Neighborhood Hits	225	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_HUMAN
NC score	0.088330 (rank : 253)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PPIP2_MOUSE
NC score	0.087815 (rank : 254)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	319	Target Neighborhood Hits	308	Shared Neighborhood Hits	69
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

HAPIP_HUMAN
NC score	0.087716 (rank : 255)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	319	Target Neighborhood Hits	350	Shared Neighborhood Hits	66
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

SH21B_HUMAN
NC score	0.087527 (rank : 256)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	319	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	O14796, Q5T0L1, Q8NI18, Q969K9	Gene names	SH2D1B, EAT2
Domain Architecture
Description	SH2 domain protein 1B (EWS/FLI1-activated transcript 2) (EAT-2).

RGNEF_MOUSE
NC score	0.086576 (rank : 257)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	319	Target Neighborhood Hits	641	Shared Neighborhood Hits	99
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ECT2_MOUSE
NC score	0.085812 (rank : 258)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	319	Target Neighborhood Hits	98	Shared Neighborhood Hits	22
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

JIP2_MOUSE
NC score	0.085207 (rank : 259)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	319	Target Neighborhood Hits	144	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

ABL1_HUMAN
NC score	0.084996 (rank : 260)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	319	Target Neighborhood Hits	1220	Shared Neighborhood Hits	126
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
NC score	0.084906 (rank : 261)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	319	Target Neighborhood Hits	1178	Shared Neighborhood Hits	126
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

JIP2_HUMAN
NC score	0.084400 (rank : 262)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	319	Target Neighborhood Hits	288	Shared Neighborhood Hits	57
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

MY18A_MOUSE
NC score	0.084082 (rank : 263)	θ value	0.0961366 (rank : 160)
Query Neighborhood Hits	319	Target Neighborhood Hits	1989	Shared Neighborhood Hits	142
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_HUMAN
NC score	0.083304 (rank : 264)	θ value	0.365318 (rank : 182)
Query Neighborhood Hits	319	Target Neighborhood Hits	1929	Shared Neighborhood Hits	145
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ITK_HUMAN
NC score	0.082891 (rank : 265)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	319	Target Neighborhood Hits	1016	Shared Neighborhood Hits	128
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ECT2_HUMAN
NC score	0.082829 (rank : 266)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	319	Target Neighborhood Hits	98	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ABL2_HUMAN
NC score	0.081779 (rank : 267)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	319	Target Neighborhood Hits	1045	Shared Neighborhood Hits	116
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

MPP4_MOUSE
NC score	0.081182 (rank : 268)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	319	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

GRB14_MOUSE
NC score	0.079654 (rank : 269)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	319	Target Neighborhood Hits	149	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLM9, Q3UI77, Q8VDI2, Q9CR03	Gene names	Grb14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

ERC2_MOUSE
NC score	0.078191 (rank : 270)	θ value	0.0330416 (rank : 139)
Query Neighborhood Hits	319	Target Neighborhood Hits	1166	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

GRB14_HUMAN
NC score	0.077695 (rank : 271)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	319	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

SHC3_MOUSE
NC score	0.077689 (rank : 272)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	319	Target Neighborhood Hits	151	Shared Neighborhood Hits	46
SwissProt Accessions	Q61120	Gene names	Shc3, Nshc, ShcC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).

APS_HUMAN
NC score	0.077351 (rank : 273)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	319	Target Neighborhood Hits	162	Shared Neighborhood Hits	39
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

SHE_MOUSE
NC score	0.077292 (rank : 274)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	319	Target Neighborhood Hits	169	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

K0555_HUMAN
NC score	0.077233 (rank : 275)	θ value	4.03905 (rank : 272)
Query Neighborhood Hits	319	Target Neighborhood Hits	880	Shared Neighborhood Hits	106
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

SHC1_HUMAN
NC score	0.076745 (rank : 276)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	319	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
NC score	0.076691 (rank : 277)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	319	Target Neighborhood Hits	180	Shared Neighborhood Hits	47
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

MYH11_MOUSE
NC score	0.076555 (rank : 278)	θ value	3.0926 (rank : 258)
Query Neighborhood Hits	319	Target Neighborhood Hits	1777	Shared Neighborhood Hits	145
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

ARHGC_HUMAN
NC score	0.076369 (rank : 279)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	319	Target Neighborhood Hits	351	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

MYH11_HUMAN
NC score	0.076346 (rank : 280)	θ value	3.0926 (rank : 257)
Query Neighborhood Hits	319	Target Neighborhood Hits	1806	Shared Neighborhood Hits	148
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RBP24_HUMAN
NC score	0.076077 (rank : 281)	θ value	0.125558 (rank : 166)
Query Neighborhood Hits	319	Target Neighborhood Hits	1559	Shared Neighborhood Hits	130
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.076015 (rank : 282)	θ value	0.125558 (rank : 164)
Query Neighborhood Hits	319	Target Neighborhood Hits	1558	Shared Neighborhood Hits	129
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

ERC2_HUMAN
NC score	0.075843 (rank : 283)	θ value	0.0563607 (rank : 152)
Query Neighborhood Hits	319	Target Neighborhood Hits	1156	Shared Neighborhood Hits	112
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ITK_MOUSE
NC score	0.075313 (rank : 284)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	319	Target Neighborhood Hits	985	Shared Neighborhood Hits	115
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

MPP4_HUMAN
NC score	0.075242 (rank : 285)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	319	Target Neighborhood Hits	205	Shared Neighborhood Hits	57
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

ARHGC_MOUSE
NC score	0.075071 (rank : 286)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	319	Target Neighborhood Hits	344	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BCR_HUMAN
NC score	0.074470 (rank : 287)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	319	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

EP15_MOUSE
NC score	0.074435 (rank : 288)	θ value	0.813845 (rank : 202)
Query Neighborhood Hits	319	Target Neighborhood Hits	820	Shared Neighborhood Hits	81
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ARHGB_HUMAN
NC score	0.074223 (rank : 289)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	319	Target Neighborhood Hits	375	Shared Neighborhood Hits	34
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SHB_MOUSE
NC score	0.074223 (rank : 290)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	319	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

ARHG1_HUMAN
NC score	0.074028 (rank : 291)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	319	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

CSKP_HUMAN
NC score	0.074026 (rank : 292)	θ value	0.000270298 (rank : 86)
Query Neighborhood Hits	319	Target Neighborhood Hits	1022	Shared Neighborhood Hits	117
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

SHE_HUMAN
NC score	0.073970 (rank : 293)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	319	Target Neighborhood Hits	164	Shared Neighborhood Hits	43
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

CSKP_MOUSE
NC score	0.073614 (rank : 294)	θ value	0.00035302 (rank : 89)
Query Neighborhood Hits	319	Target Neighborhood Hits	1027	Shared Neighborhood Hits	124
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CTBL1_MOUSE
NC score	0.073425 (rank : 295)	θ value	0.0330416 (rank : 137)
Query Neighborhood Hits	319	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CWL8, Q3UL41, Q80X64, Q8VHE3	Gene names	Ctnnbl1
Domain Architecture	No domain graphic available
Description	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP).

MYH2_HUMAN
NC score	0.073415 (rank : 296)	θ value	0.279714 (rank : 177)
Query Neighborhood Hits	319	Target Neighborhood Hits	1491	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH1_MOUSE
NC score	0.073099 (rank : 297)	θ value	1.38821 (rank : 219)
Query Neighborhood Hits	319	Target Neighborhood Hits	1461	Shared Neighborhood Hits	130
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_MOUSE
NC score	0.072806 (rank : 298)	θ value	0.365318 (rank : 183)
Query Neighborhood Hits	319	Target Neighborhood Hits	1476	Shared Neighborhood Hits	127
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

RAD50_MOUSE
NC score	0.072523 (rank : 299)	θ value	0.365318 (rank : 186)
Query Neighborhood Hits	319	Target Neighborhood Hits	1366	Shared Neighborhood Hits	120
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

MYH9_MOUSE
NC score	0.072487 (rank : 300)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	319	Target Neighborhood Hits	1829	Shared Neighborhood Hits	139
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PCNT_HUMAN
NC score	0.072440 (rank : 301)	θ value	3.0926 (rank : 260)
Query Neighborhood Hits	319	Target Neighborhood Hits	1551	Shared Neighborhood Hits	135
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

FGD4_MOUSE
NC score	0.072325 (rank : 302)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

SHB_HUMAN
NC score	0.072230 (rank : 303)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	319	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHC3_HUMAN
NC score	0.072217 (rank : 304)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	319	Target Neighborhood Hits	155	Shared Neighborhood Hits	41
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

GOGA4_MOUSE
NC score	0.072172 (rank : 305)	θ value	3.0926 (rank : 255)
Query Neighborhood Hits	319	Target Neighborhood Hits	1939	Shared Neighborhood Hits	136
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SHC2_MOUSE
NC score	0.071862 (rank : 306)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	319	Target Neighborhood Hits	144	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

FGD4_HUMAN
NC score	0.071835 (rank : 307)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	319	Target Neighborhood Hits	219	Shared Neighborhood Hits	35
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

SRMS_MOUSE
NC score	0.071736 (rank : 308)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	319	Target Neighborhood Hits	964	Shared Neighborhood Hits	100
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

SHD_MOUSE
NC score	0.071688 (rank : 309)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	319	Target Neighborhood Hits	137	Shared Neighborhood Hits	42
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

MYH9_HUMAN
NC score	0.071560 (rank : 310)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	319	Target Neighborhood Hits	1762	Shared Neighborhood Hits	138
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

EP15_HUMAN
NC score	0.071525 (rank : 311)	θ value	1.38821 (rank : 214)
Query Neighborhood Hits	319	Target Neighborhood Hits	1021	Shared Neighborhood Hits	92
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MYH1_HUMAN
NC score	0.071451 (rank : 312)	θ value	3.0926 (rank : 259)
Query Neighborhood Hits	319	Target Neighborhood Hits	1478	Shared Neighborhood Hits	126
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

SHC2_HUMAN
NC score	0.071431 (rank : 313)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	319	Target Neighborhood Hits	170	Shared Neighborhood Hits	45
SwissProt Accessions	P98077, O60230, Q9NPL5, Q9UCX4	Gene names	SHC2, SCK, SHCB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck).

MYH8_MOUSE
NC score	0.071330 (rank : 314)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	319	Target Neighborhood Hits	1600	Shared Neighborhood Hits	134
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH13_HUMAN
NC score	0.071314 (rank : 315)	θ value	1.81305 (rank : 232)
Query Neighborhood Hits	319	Target Neighborhood Hits	1504	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

FGD3_MOUSE
NC score	0.071195 (rank : 316)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	319	Target Neighborhood Hits	257	Shared Neighborhood Hits	29
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

MYH3_HUMAN
NC score	0.071055 (rank : 317)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	319	Target Neighborhood Hits	1660	Shared Neighborhood Hits	135
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

AZI1_MOUSE
NC score	0.070795 (rank : 318)	θ value	0.125558 (rank : 163)
Query Neighborhood Hits	319	Target Neighborhood Hits	990	Shared Neighborhood Hits	105
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

PLCB3_HUMAN
NC score	0.070786 (rank : 319)	θ value	0.279714 (rank : 179)
Query Neighborhood Hits	319	Target Neighborhood Hits	445	Shared Neighborhood Hits	74
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

CASC5_HUMAN
NC score	0.070256 (rank : 320)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	319	Target Neighborhood Hits	376	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

HSH2D_HUMAN
NC score	0.070256 (rank : 321)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	319	Target Neighborhood Hits	159	Shared Neighborhood Hits	34
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

MYH8_HUMAN
NC score	0.070098 (rank : 322)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	319	Target Neighborhood Hits	1610	Shared Neighborhood Hits	132
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

LBC_HUMAN
NC score	0.069969 (rank : 323)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	319	Target Neighborhood Hits	90	Shared Neighborhood Hits	24
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

TRIPB_HUMAN
NC score	0.069885 (rank : 324)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	319	Target Neighborhood Hits	1587	Shared Neighborhood Hits	129
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CHIN_MOUSE
NC score	0.069721 (rank : 325)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	319	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

EEA1_HUMAN
NC score	0.069456 (rank : 326)	θ value	2.36792 (rank : 237)
Query Neighborhood Hits	319	Target Neighborhood Hits	1796	Shared Neighborhood Hits	132
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GRB7_MOUSE
NC score	0.069385 (rank : 327)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	319	Target Neighborhood Hits	157	Shared Neighborhood Hits	42
SwissProt Accessions	Q03160	Gene names	Grb7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7).

FGD2_HUMAN
NC score	0.069347 (rank : 328)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	319	Target Neighborhood Hits	151	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

MYH10_HUMAN
NC score	0.069113 (rank : 329)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	319	Target Neighborhood Hits	1620	Shared Neighborhood Hits	135
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

GOGA5_MOUSE
NC score	0.069002 (rank : 330)	θ value	0.47712 (rank : 189)
Query Neighborhood Hits	319	Target Neighborhood Hits	1434	Shared Neighborhood Hits	123
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA4_HUMAN
NC score	0.068982 (rank : 331)	θ value	4.03905 (rank : 271)
Query Neighborhood Hits	319	Target Neighborhood Hits	2034	Shared Neighborhood Hits	141
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MYH6_MOUSE
NC score	0.068939 (rank : 332)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	319	Target Neighborhood Hits	1501	Shared Neighborhood Hits	125
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH10_MOUSE
NC score	0.068911 (rank : 333)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	319	Target Neighborhood Hits	1612	Shared Neighborhood Hits	135
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ARHGF_HUMAN
NC score	0.068879 (rank : 334)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	319	Target Neighborhood Hits	214	Shared Neighborhood Hits	24
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

SH24A_HUMAN
NC score	0.068851 (rank : 335)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	319	Target Neighborhood Hits	455	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

CTBL1_HUMAN
NC score	0.068742 (rank : 336)	θ value	0.0961366 (rank : 158)
Query Neighborhood Hits	319	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYA6, Q53HI8, Q5JWZ2, Q5JWZ3, Q5JWZ7, Q5JWZ8, Q8N454, Q8NCL2, Q8TBD6, Q96KD2, Q9H7A5, Q9NQF9, Q9NTX0, Q9Y3M7	Gene names	CTNNBL1, C20orf33
Domain Architecture
Description	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19).

GNRP_MOUSE
NC score	0.068692 (rank : 337)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	319	Target Neighborhood Hits	191	Shared Neighborhood Hits	27
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

SHD_HUMAN
NC score	0.068555 (rank : 338)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	319	Target Neighborhood Hits	204	Shared Neighborhood Hits	40
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

EP15R_MOUSE
NC score	0.068510 (rank : 339)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	319	Target Neighborhood Hits	1135	Shared Neighborhood Hits	102
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

CHIN_HUMAN
NC score	0.068358 (rank : 340)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	47
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CCD46_HUMAN
NC score	0.068270 (rank : 341)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	319	Target Neighborhood Hits	1430	Shared Neighborhood Hits	132
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

TRHY_HUMAN
NC score	0.068144 (rank : 342)	θ value	0.813845 (rank : 206)
Query Neighborhood Hits	319	Target Neighborhood Hits	1385	Shared Neighborhood Hits	110
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CHIO_HUMAN
NC score	0.067883 (rank : 343)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	319	Target Neighborhood Hits	220	Shared Neighborhood Hits	45
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

EEA1_MOUSE
NC score	0.067824 (rank : 344)	θ value	0.813845 (rank : 201)
Query Neighborhood Hits	319	Target Neighborhood Hits	1637	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

LNK_HUMAN
NC score	0.067632 (rank : 345)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	319	Target Neighborhood Hits	151	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

MYH6_HUMAN
NC score	0.067510 (rank : 346)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	319	Target Neighborhood Hits	1426	Shared Neighborhood Hits	116
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CCHCR_HUMAN
NC score	0.067145 (rank : 347)	θ value	0.62314 (rank : 195)
Query Neighborhood Hits	319	Target Neighborhood Hits	717	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

MYH7_HUMAN
NC score	0.067037 (rank : 348)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	319	Target Neighborhood Hits	1559	Shared Neighborhood Hits	119
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

XE7_HUMAN
NC score	0.067003 (rank : 349)	θ value	0.813845 (rank : 207)
Query Neighborhood Hits	319	Target Neighborhood Hits	738	Shared Neighborhood Hits	78
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

MYO5C_HUMAN
NC score	0.066973 (rank : 350)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	319	Target Neighborhood Hits	1206	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

EP15R_HUMAN
NC score	0.066840 (rank : 351)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	319	Target Neighborhood Hits	1083	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

FGD3_HUMAN
NC score	0.066589 (rank : 352)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	319	Target Neighborhood Hits	249	Shared Neighborhood Hits	27
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

MY18B_HUMAN
NC score	0.066545 (rank : 353)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	319	Target Neighborhood Hits	1299	Shared Neighborhood Hits	105
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CP250_MOUSE
NC score	0.066462 (rank : 354)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	319	Target Neighborhood Hits	1583	Shared Neighborhood Hits	125
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MATK_MOUSE
NC score	0.066219 (rank : 355)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	319	Target Neighborhood Hits	952	Shared Neighborhood Hits	79
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MYH4_HUMAN
NC score	0.066181 (rank : 356)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	319	Target Neighborhood Hits	1377	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

GOGA3_MOUSE
NC score	0.066145 (rank : 357)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	319	Target Neighborhood Hits	1437	Shared Neighborhood Hits	124
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

REST_HUMAN
NC score	0.066120 (rank : 358)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	319	Target Neighborhood Hits	1605	Shared Neighborhood Hits	124
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CCD46_MOUSE
NC score	0.066038 (rank : 359)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	319	Target Neighborhood Hits	1405	Shared Neighborhood Hits	127
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

AZI1_HUMAN
NC score	0.065972 (rank : 360)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	319	Target Neighborhood Hits	1000	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

FUT8_HUMAN
NC score	0.065959 (rank : 361)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	319	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYC5, O00235, Q9BYC6, Q9P2U5, Q9P2U6	Gene names	FUT8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

LNK_MOUSE
NC score	0.065926 (rank : 362)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	319	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	O09039	Gene names	Lnk
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

ABR_HUMAN
NC score	0.065903 (rank : 363)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	319	Target Neighborhood Hits	166	Shared Neighborhood Hits	31
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

MYH14_MOUSE
NC score	0.065804 (rank : 364)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	319	Target Neighborhood Hits	1225	Shared Neighborhood Hits	110
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

BRE1A_HUMAN
NC score	0.065698 (rank : 365)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	319	Target Neighborhood Hits	1071	Shared Neighborhood Hits	106
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CYLN2_MOUSE
NC score	0.065655 (rank : 366)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	319	Target Neighborhood Hits	1002	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

PCNT_MOUSE
NC score	0.065603 (rank : 367)	θ value	0.47712 (rank : 191)
Query Neighborhood Hits	319	Target Neighborhood Hits	1207	Shared Neighborhood Hits	109
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

FUT8_MOUSE
NC score	0.065451 (rank : 368)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	319	Target Neighborhood Hits	115	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTS2, Q921U1	Gene names	Fut8
Domain Architecture
Description	Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68) (Glycoprotein 6-alpha-L- fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (alpha1-6FucT) (Fucosyltransferase 8).

FGD2_MOUSE
NC score	0.065394 (rank : 369)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	319	Target Neighborhood Hits	163	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

MPP3_HUMAN
NC score	0.065225 (rank : 370)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	319	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

CP250_HUMAN
NC score	0.065218 (rank : 371)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	319	Target Neighborhood Hits	1805	Shared Neighborhood Hits	135
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

ARHG2_HUMAN
NC score	0.065061 (rank : 372)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	319	Target Neighborhood Hits	142	Shared Neighborhood Hits	26
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

PLCB3_MOUSE
NC score	0.065052 (rank : 373)	θ value	0.00869519 (rank : 130)
Query Neighborhood Hits	319	Target Neighborhood Hits	344	Shared Neighborhood Hits	56
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

RB6I2_MOUSE
NC score	0.065008 (rank : 374)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	319	Target Neighborhood Hits	1433	Shared Neighborhood Hits	116
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

OPHN1_HUMAN
NC score	0.064980 (rank : 375)	θ value	0.62314 (rank : 199)
Query Neighborhood Hits	319	Target Neighborhood Hits	161	Shared Neighborhood Hits	27
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

MPP3_MOUSE
NC score	0.064921 (rank : 376)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	319	Target Neighborhood Hits	165	Shared Neighborhood Hits	37
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

GOGB1_HUMAN
NC score	0.064790 (rank : 377)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	319	Target Neighborhood Hits	2297	Shared Neighborhood Hits	143
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CCHCR_MOUSE
NC score	0.064739 (rank : 378)	θ value	1.81305 (rank : 224)
Query Neighborhood Hits	319	Target Neighborhood Hits	932	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CYLN2_HUMAN
NC score	0.064540 (rank : 379)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	319	Target Neighborhood Hits	1004	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CCD41_MOUSE
NC score	0.064529 (rank : 380)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	319	Target Neighborhood Hits	1399	Shared Neighborhood Hits	114
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

SRMS_HUMAN
NC score	0.064449 (rank : 381)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	319	Target Neighborhood Hits	946	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

ARHG2_MOUSE
NC score	0.064322 (rank : 382)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	319	Target Neighborhood Hits	120	Shared Neighborhood Hits	24
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

MYO5A_HUMAN
NC score	0.064295 (rank : 383)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	319	Target Neighborhood Hits	1092	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

DLG2_HUMAN
NC score	0.064155 (rank : 384)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	319	Target Neighborhood Hits	279	Shared Neighborhood Hits	75
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LIPA2_MOUSE
NC score	0.064097 (rank : 385)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	319	Target Neighborhood Hits	1282	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

RAD50_HUMAN
NC score	0.063739 (rank : 386)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	319	Target Neighborhood Hits	1317	Shared Neighborhood Hits	116
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RB6I2_HUMAN
NC score	0.063658 (rank : 387)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	319	Target Neighborhood Hits	1584	Shared Neighborhood Hits	120
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

GCC2_MOUSE
NC score	0.063653 (rank : 388)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	319	Target Neighborhood Hits	1619	Shared Neighborhood Hits	129
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

BRE1A_MOUSE
NC score	0.063460 (rank : 389)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	319	Target Neighborhood Hits	1025	Shared Neighborhood Hits	105
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

FLIP1_HUMAN
NC score	0.063228 (rank : 390)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	319	Target Neighborhood Hits	1405	Shared Neighborhood Hits	125
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CENPF_HUMAN
NC score	0.063228 (rank : 391)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	319	Target Neighborhood Hits	1932	Shared Neighborhood Hits	145
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CI093_HUMAN
NC score	0.062877 (rank : 392)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	319	Target Neighborhood Hits	1088	Shared Neighborhood Hits	109
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

PEPL_MOUSE
NC score	0.062829 (rank : 393)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	319	Target Neighborhood Hits	1105	Shared Neighborhood Hits	113
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

HOOK3_HUMAN
NC score	0.062785 (rank : 394)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	319	Target Neighborhood Hits	1070	Shared Neighborhood Hits	108
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

GOGA2_HUMAN
NC score	0.062628 (rank : 395)	θ value	2.36792 (rank : 241)
Query Neighborhood Hits	319	Target Neighborhood Hits	856	Shared Neighborhood Hits	92
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

DESP_HUMAN
NC score	0.062615 (rank : 396)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	319	Target Neighborhood Hits	1470	Shared Neighborhood Hits	131
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

LIPA1_HUMAN
NC score	0.062563 (rank : 397)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	319	Target Neighborhood Hits	1294	Shared Neighborhood Hits	124
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MYH14_HUMAN
NC score	0.062534 (rank : 398)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	319	Target Neighborhood Hits	995	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

SH21A_MOUSE
NC score	0.062444 (rank : 399)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	319	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

MATK_HUMAN
NC score	0.062381 (rank : 400)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	319	Target Neighborhood Hits	954	Shared Neighborhood Hits	76
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

NDE1_HUMAN
NC score	0.062211 (rank : 401)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	319	Target Neighborhood Hits	823	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

DLG2_MOUSE
NC score	0.062095 (rank : 402)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	319	Target Neighborhood Hits	271	Shared Neighborhood Hits	75
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

ARHG1_MOUSE
NC score	0.062087 (rank : 403)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	319	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

GRB7_HUMAN
NC score	0.062021 (rank : 404)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	319	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GNRP_HUMAN
NC score	0.061995 (rank : 405)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	319	Target Neighborhood Hits	239	Shared Neighborhood Hits	29
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

AKAP9_HUMAN
NC score	0.061983 (rank : 406)	θ value	4.03905 (rank : 264)
Query Neighborhood Hits	319	Target Neighborhood Hits	1710	Shared Neighborhood Hits	134
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

MYO5A_MOUSE
NC score	0.061883 (rank : 407)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	319	Target Neighborhood Hits	1117	Shared Neighborhood Hits	104
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

GOGA5_HUMAN
NC score	0.061768 (rank : 408)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	319	Target Neighborhood Hits	1168	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SH21A_HUMAN
NC score	0.061754 (rank : 409)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	319	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

CE290_HUMAN
NC score	0.061736 (rank : 410)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	319	Target Neighborhood Hits	1553	Shared Neighborhood Hits	125
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

NUMA1_HUMAN
NC score	0.061693 (rank : 411)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	319	Target Neighborhood Hits	1523	Shared Neighborhood Hits	125
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CEP63_HUMAN
NC score	0.061553 (rank : 412)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	319	Target Neighborhood Hits	1005	Shared Neighborhood Hits	104
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

PIBF1_HUMAN
NC score	0.061355 (rank : 413)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	319	Target Neighborhood Hits	1041	Shared Neighborhood Hits	103
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

DLG5_HUMAN
NC score	0.061318 (rank : 414)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	319	Target Neighborhood Hits	1088	Shared Neighborhood Hits	138
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

HOOK3_MOUSE
NC score	0.061279 (rank : 415)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	319	Target Neighborhood Hits	1007	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

BPAEA_MOUSE
NC score	0.061075 (rank : 416)	θ value	5.27518 (rank : 280)
Query Neighborhood Hits	319	Target Neighborhood Hits	1480	Shared Neighborhood Hits	124
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

NIN_HUMAN
NC score	0.061033 (rank : 417)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	319	Target Neighborhood Hits	1416	Shared Neighborhood Hits	119
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIN_MOUSE
NC score	0.060958 (rank : 418)	θ value	5.27518 (rank : 283)
Query Neighborhood Hits	319	Target Neighborhood Hits	1376	Shared Neighborhood Hits	117
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CNTRB_MOUSE
NC score	0.060896 (rank : 419)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	319	Target Neighborhood Hits	1029	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

TRIO_HUMAN
NC score	0.060823 (rank : 420)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	319	Target Neighborhood Hits	1580	Shared Neighborhood Hits	141
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

CCD13_HUMAN
NC score	0.060573 (rank : 421)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	319	Target Neighborhood Hits	721	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

AMOL1_HUMAN
NC score	0.060428 (rank : 422)	θ value	0.21417 (rank : 173)
Query Neighborhood Hits	319	Target Neighborhood Hits	435	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

FGD1_HUMAN
NC score	0.060369 (rank : 423)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	319	Target Neighborhood Hits	367	Shared Neighborhood Hits	36
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SMC1A_MOUSE
NC score	0.060204 (rank : 424)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	319	Target Neighborhood Hits	1384	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

DLG3_HUMAN
NC score	0.060162 (rank : 425)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	319	Target Neighborhood Hits	269	Shared Neighborhood Hits	72
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

GOGA1_HUMAN
NC score	0.060109 (rank : 426)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	319	Target Neighborhood Hits	1222	Shared Neighborhood Hits	110
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

REST_MOUSE
NC score	0.059926 (rank : 427)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	319	Target Neighborhood Hits	1506	Shared Neighborhood Hits	112
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

PKHG4_HUMAN
NC score	0.059783 (rank : 428)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	319	Target Neighborhood Hits	200	Shared Neighborhood Hits	21
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

GOGA2_MOUSE
NC score	0.059685 (rank : 429)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	319	Target Neighborhood Hits	944	Shared Neighborhood Hits	101
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

CF060_HUMAN
NC score	0.059613 (rank : 430)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	319	Target Neighborhood Hits	1270	Shared Neighborhood Hits	118
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

DLG3_MOUSE
NC score	0.059557 (rank : 431)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	319	Target Neighborhood Hits	274	Shared Neighborhood Hits	72
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

SMC1A_HUMAN
NC score	0.059553 (rank : 432)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	319	Target Neighborhood Hits	1346	Shared Neighborhood Hits	118
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SKIL_MOUSE
NC score	0.059448 (rank : 433)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	319	Target Neighborhood Hits	719	Shared Neighborhood Hits	90
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

CING_MOUSE
NC score	0.059377 (rank : 434)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	319	Target Neighborhood Hits	1432	Shared Neighborhood Hits	115
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

MYO10_HUMAN
NC score	0.059254 (rank : 435)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	319	Target Neighborhood Hits	920	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

GOGA1_MOUSE
NC score	0.059189 (rank : 436)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	319	Target Neighborhood Hits	994	Shared Neighborhood Hits	106
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

SYNE1_HUMAN
NC score	0.059142 (rank : 437)	θ value	1.81305 (rank : 234)
Query Neighborhood Hits	319	Target Neighborhood Hits	1484	Shared Neighborhood Hits	120
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CCD21_MOUSE
NC score	0.059130 (rank : 438)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	319	Target Neighborhood Hits	1135	Shared Neighborhood Hits	106
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CARD9_HUMAN
NC score	0.059092 (rank : 439)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	319	Target Neighborhood Hits	602	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

PLCB4_HUMAN
NC score	0.059010 (rank : 440)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	319	Target Neighborhood Hits	658	Shared Neighborhood Hits	82
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

SH2D3_MOUSE
NC score	0.058955 (rank : 441)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	319	Target Neighborhood Hits	174	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

OPTN_MOUSE
NC score	0.058888 (rank : 442)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	319	Target Neighborhood Hits	1120	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RHG12_MOUSE
NC score	0.058876 (rank : 443)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	319	Target Neighborhood Hits	204	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

PEPL_HUMAN
NC score	0.058859 (rank : 444)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	319	Target Neighborhood Hits	1141	Shared Neighborhood Hits	105
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

CK5P2_HUMAN
NC score	0.058786 (rank : 445)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	319	Target Neighborhood Hits	1433	Shared Neighborhood Hits	121
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

GOGA3_HUMAN
NC score	0.058694 (rank : 446)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	319	Target Neighborhood Hits	1317	Shared Neighborhood Hits	113
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

APS_MOUSE
NC score	0.058615 (rank : 447)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	319	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

GRAP1_MOUSE
NC score	0.058575 (rank : 448)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	319	Target Neighborhood Hits	1234	Shared Neighborhood Hits	112
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

CP135_MOUSE
NC score	0.058557 (rank : 449)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	319	Target Neighborhood Hits	1278	Shared Neighborhood Hits	111
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

OPHN1_MOUSE
NC score	0.058350 (rank : 450)	θ value	2.36792 (rank : 248)
Query Neighborhood Hits	319	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

GRB10_MOUSE
NC score	0.058330 (rank : 451)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	319	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

CP135_HUMAN
NC score	0.058249 (rank : 452)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	319	Target Neighborhood Hits	1290	Shared Neighborhood Hits	114
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

KTN1_MOUSE
NC score	0.058194 (rank : 453)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	319	Target Neighborhood Hits	1324	Shared Neighborhood Hits	120
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

CCD21_HUMAN
NC score	0.058178 (rank : 454)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	319	Target Neighborhood Hits	1228	Shared Neighborhood Hits	112
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

TUFT1_HUMAN
NC score	0.058117 (rank : 455)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	319	Target Neighborhood Hits	686	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CU013_HUMAN
NC score	0.058102 (rank : 456)	θ value	4.03905 (rank : 268)
Query Neighborhood Hits	319	Target Neighborhood Hits	405	Shared Neighborhood Hits	74
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CING_HUMAN
NC score	0.058019 (rank : 457)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	319	Target Neighborhood Hits	1275	Shared Neighborhood Hits	114
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

GAS8_HUMAN
NC score	0.058015 (rank : 458)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	319	Target Neighborhood Hits	819	Shared Neighborhood Hits	98
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

NEST_HUMAN
NC score	0.057863 (rank : 459)	θ value	0.279714 (rank : 178)
Query Neighborhood Hits	319	Target Neighborhood Hits	1305	Shared Neighborhood Hits	99
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

IFT74_HUMAN
NC score	0.057848 (rank : 460)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	319	Target Neighborhood Hits	949	Shared Neighborhood Hits	101
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CROCC_HUMAN
NC score	0.057830 (rank : 461)	θ value	1.81305 (rank : 225)
Query Neighborhood Hits	319	Target Neighborhood Hits	1409	Shared Neighborhood Hits	117
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA6_HUMAN
NC score	0.057761 (rank : 462)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	319	Target Neighborhood Hits	1007	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

FGD1_MOUSE
NC score	0.057751 (rank : 463)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	319	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

GRB10_HUMAN
NC score	0.057684 (rank : 464)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	319	Target Neighborhood Hits	147	Shared Neighborhood Hits	41
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

CE152_HUMAN
NC score	0.057655 (rank : 465)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	319	Target Neighborhood Hits	976	Shared Neighborhood Hits	101
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

FER_HUMAN
NC score	0.057603 (rank : 466)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	319	Target Neighborhood Hits	1278	Shared Neighborhood Hits	123
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

SH22A_MOUSE
NC score	0.057576 (rank : 467)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	319	Target Neighborhood Hits	179	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

PLCB1_HUMAN
NC score	0.057452 (rank : 468)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	319	Target Neighborhood Hits	614	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SYCP1_MOUSE
NC score	0.057284 (rank : 469)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	319	Target Neighborhood Hits	1456	Shared Neighborhood Hits	120
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CROCC_MOUSE
NC score	0.057252 (rank : 470)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	319	Target Neighborhood Hits	1460	Shared Neighborhood Hits	117
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MYO5B_HUMAN
NC score	0.057062 (rank : 471)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	319	Target Neighborhood Hits	911	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO6_HUMAN
NC score	0.057028 (rank : 472)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	319	Target Neighborhood Hits	727	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

CASP_MOUSE
NC score	0.056940 (rank : 473)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	319	Target Neighborhood Hits	1152	Shared Neighborhood Hits	116
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

AMOL1_MOUSE
NC score	0.056823 (rank : 474)	θ value	0.279714 (rank : 176)
Query Neighborhood Hits	319	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

SMC2_HUMAN
NC score	0.056811 (rank : 475)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	319	Target Neighborhood Hits	1405	Shared Neighborhood Hits	123
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

HMMR_MOUSE
NC score	0.056744 (rank : 476)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	319	Target Neighborhood Hits	1178	Shared Neighborhood Hits	108
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CCD39_MOUSE
NC score	0.056692 (rank : 477)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	319	Target Neighborhood Hits	1026	Shared Neighborhood Hits	103
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

HOOK1_HUMAN
NC score	0.056679 (rank : 478)	θ value	0.365318 (rank : 181)
Query Neighborhood Hits	319	Target Neighborhood Hits	942	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

DMD_HUMAN
NC score	0.056565 (rank : 479)	θ value	3.0926 (rank : 253)
Query Neighborhood Hits	319	Target Neighborhood Hits	1135	Shared Neighborhood Hits	107
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

RHG12_HUMAN
NC score	0.056500 (rank : 480)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	319	Target Neighborhood Hits	190	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

DLG4_HUMAN
NC score	0.056465 (rank : 481)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	319	Target Neighborhood Hits	286	Shared Neighborhood Hits	71
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

FLIP1_MOUSE
NC score	0.056400 (rank : 482)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	319	Target Neighborhood Hits	1176	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

RHG09_HUMAN
NC score	0.056188 (rank : 483)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	319	Target Neighborhood Hits	186	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

IFT81_MOUSE
NC score	0.056148 (rank : 484)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	319	Target Neighborhood Hits	959	Shared Neighborhood Hits	91
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

FARP2_MOUSE
NC score	0.056033 (rank : 485)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	319	Target Neighborhood Hits	209	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

CN145_HUMAN
NC score	0.055970 (rank : 486)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	319	Target Neighborhood Hits	1196	Shared Neighborhood Hits	111
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MYO6_MOUSE
NC score	0.055943 (rank : 487)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	319	Target Neighborhood Hits	586	Shared Neighborhood Hits	69
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

CT2NL_HUMAN
NC score	0.055918 (rank : 488)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	319	Target Neighborhood Hits	1059	Shared Neighborhood Hits	103
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RABE1_HUMAN
NC score	0.055911 (rank : 489)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	319	Target Neighborhood Hits	1104	Shared Neighborhood Hits	107
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

SDCG8_HUMAN
NC score	0.055864 (rank : 490)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	319	Target Neighborhood Hits	1002	Shared Neighborhood Hits	93
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

RRBP1_MOUSE
NC score	0.055861 (rank : 491)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	319	Target Neighborhood Hits	1650	Shared Neighborhood Hits	116
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

DLG1_HUMAN
NC score	0.055815 (rank : 492)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	319	Target Neighborhood Hits	290	Shared Neighborhood Hits	67
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

FGD6_MOUSE
NC score	0.055773 (rank : 493)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	319	Target Neighborhood Hits	282	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

CCD91_HUMAN
NC score	0.055756 (rank : 494)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	319	Target Neighborhood Hits	868	Shared Neighborhood Hits	89
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CASP_HUMAN
NC score	0.055683 (rank : 495)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	319	Target Neighborhood Hits	1131	Shared Neighborhood Hits	110
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CENPE_HUMAN
NC score	0.055659 (rank : 496)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	319	Target Neighborhood Hits	2060	Shared Neighborhood Hits	145
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

SH2D3_HUMAN
NC score	0.055584 (rank : 497)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	319	Target Neighborhood Hits	188	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

CI039_HUMAN
NC score	0.055560 (rank : 498)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	319	Target Neighborhood Hits	1171	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

S3TC2_MOUSE
NC score	0.055532 (rank : 499)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	319	Target Neighborhood Hits	83	Shared Neighborhood Hits	44
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

LIPA2_HUMAN
NC score	0.055515 (rank : 500)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	319	Target Neighborhood Hits	1044	Shared Neighborhood Hits	108
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TUFT1_MOUSE
NC score	0.055450 (rank : 501)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	319	Target Neighborhood Hits	732	Shared Neighborhood Hits	89
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

INVO_HUMAN
NC score	0.055446 (rank : 502)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	319	Target Neighborhood Hits	636	Shared Neighborhood Hits	75
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

HOME2_MOUSE
NC score	0.055407 (rank : 503)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	319	Target Neighborhood Hits	882	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

PTN11_HUMAN
NC score	0.055333 (rank : 504)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	45
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.055315 (rank : 505)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	319	Target Neighborhood Hits	227	Shared Neighborhood Hits	44
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

BRE1B_HUMAN
NC score	0.055303 (rank : 506)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	319	Target Neighborhood Hits	1040	Shared Neighborhood Hits	93
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BCAR3_HUMAN
NC score	0.055232 (rank : 507)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	319	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	O75815, Q6UW40, Q9BR50	Gene names	BCAR3, NSP2, SH2D3B
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (SH2 domain- containing protein 3B) (Novel SH2-containing protein 2).

IFT74_MOUSE
NC score	0.055167 (rank : 508)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	319	Target Neighborhood Hits	939	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
NC score	0.055144 (rank : 509)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	319	Target Neighborhood Hits	893	Shared Neighborhood Hits	95
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

LCP2_MOUSE
NC score	0.055124 (rank : 510)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	319	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

TPR_HUMAN
NC score	0.055112 (rank : 511)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	319	Target Neighborhood Hits	1921	Shared Neighborhood Hits	127
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

INCE_MOUSE
NC score	0.055033 (rank : 512)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	319	Target Neighborhood Hits	903	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

DMD_MOUSE
NC score	0.054869 (rank : 513)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	319	Target Neighborhood Hits	1111	Shared Neighborhood Hits	113
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

HMMR_HUMAN
NC score	0.054868 (rank : 514)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	319	Target Neighborhood Hits	1082	Shared Neighborhood Hits	100
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

PLCB2_HUMAN
NC score	0.054809 (rank : 515)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	319	Target Neighborhood Hits	608	Shared Neighborhood Hits	76
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

SYCP1_HUMAN
NC score	0.054697 (rank : 516)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	319	Target Neighborhood Hits	1313	Shared Neighborhood Hits	112
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ANR26_MOUSE
NC score	0.054691 (rank : 517)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	319	Target Neighborhood Hits	1554	Shared Neighborhood Hits	119
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GRAP1_HUMAN
NC score	0.054669 (rank : 518)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	319	Target Neighborhood Hits	944	Shared Neighborhood Hits	104
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

ENAH_HUMAN
NC score	0.054383 (rank : 519)	θ value	1.81305 (rank : 226)
Query Neighborhood Hits	319	Target Neighborhood Hits	784	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

BCAR3_MOUSE
NC score	0.054258 (rank : 520)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	319	Target Neighborhood Hits	127	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

DLG4_MOUSE
NC score	0.054237 (rank : 521)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	319	Target Neighborhood Hits	282	Shared Neighborhood Hits	69
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

CCD39_HUMAN
NC score	0.054138 (rank : 522)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	319	Target Neighborhood Hits	868	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

TPM3_HUMAN
NC score	0.054009 (rank : 523)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	319	Target Neighborhood Hits	689	Shared Neighborhood Hits	78
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

LRRF2_HUMAN
NC score	0.053902 (rank : 524)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	319	Target Neighborhood Hits	791	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

TAXB1_MOUSE
NC score	0.053874 (rank : 525)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	319	Target Neighborhood Hits	886	Shared Neighborhood Hits	96
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TEX9_MOUSE
NC score	0.053795 (rank : 526)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	319	Target Neighborhood Hits	581	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TMF1_HUMAN
NC score	0.053789 (rank : 527)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	319	Target Neighborhood Hits	987	Shared Neighborhood Hits	96
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

LRC45_MOUSE
NC score	0.053766 (rank : 528)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	319	Target Neighborhood Hits	959	Shared Neighborhood Hits	102
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MYO9B_MOUSE
NC score	0.053718 (rank : 529)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	319	Target Neighborhood Hits	311	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.053619 (rank : 530)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	319	Target Neighborhood Hits	641	Shared Neighborhood Hits	44
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CCD41_HUMAN
NC score	0.053612 (rank : 531)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	319	Target Neighborhood Hits	1139	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

DLG1_MOUSE
NC score	0.053453 (rank : 532)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	319	Target Neighborhood Hits	285	Shared Neighborhood Hits	66
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

CTRO_MOUSE
NC score	0.053320 (rank : 533)	θ value	0.0330416 (rank : 138)
Query Neighborhood Hits	319	Target Neighborhood Hits	2344	Shared Neighborhood Hits	153
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MD1L1_MOUSE
NC score	0.053320 (rank : 534)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	319	Target Neighborhood Hits	1001	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

LRC45_HUMAN
NC score	0.053266 (rank : 535)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	319	Target Neighborhood Hits	933	Shared Neighborhood Hits	100
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

TPM3_MOUSE
NC score	0.053228 (rank : 536)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	319	Target Neighborhood Hits	676	Shared Neighborhood Hits	78
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

EVPL_MOUSE
NC score	0.053194 (rank : 537)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	319	Target Neighborhood Hits	952	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

GCC1_MOUSE
NC score	0.053175 (rank : 538)	θ value	4.03905 (rank : 270)
Query Neighborhood Hits	319	Target Neighborhood Hits	777	Shared Neighborhood Hits	89
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

TAXB1_HUMAN
NC score	0.053128 (rank : 539)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	319	Target Neighborhood Hits	829	Shared Neighborhood Hits	88
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

RABE1_MOUSE
NC score	0.053086 (rank : 540)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	319	Target Neighborhood Hits	1105	Shared Neighborhood Hits	109
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

TACC3_HUMAN
NC score	0.053045 (rank : 541)	θ value	3.0926 (rank : 263)
Query Neighborhood Hits	319	Target Neighborhood Hits	779	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

INCE_HUMAN
NC score	0.052874 (rank : 542)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	319	Target Neighborhood Hits	978	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

SM1L2_HUMAN
NC score	0.052872 (rank : 543)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	319	Target Neighborhood Hits	1019	Shared Neighborhood Hits	103
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

LIPA3_HUMAN
NC score	0.052711 (rank : 544)	θ value	1.81305 (rank : 229)
Query Neighborhood Hits	319	Target Neighborhood Hits	828	Shared Neighborhood Hits	91
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

ANR26_HUMAN
NC score	0.052653 (rank : 545)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	319	Target Neighborhood Hits	1614	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RFIP3_HUMAN
NC score	0.052605 (rank : 546)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	319	Target Neighborhood Hits	1055	Shared Neighborhood Hits	100
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

HOOK2_HUMAN
NC score	0.052552 (rank : 547)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	319	Target Neighborhood Hits	714	Shared Neighborhood Hits	88
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

PLCB1_MOUSE
NC score	0.052537 (rank : 548)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	319	Target Neighborhood Hits	531	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

NEMO_HUMAN
NC score	0.052530 (rank : 549)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	319	Target Neighborhood Hits	820	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

HOOK1_MOUSE
NC score	0.052519 (rank : 550)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	319	Target Neighborhood Hits	910	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

MYO15_MOUSE
NC score	0.052495 (rank : 551)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	319	Target Neighborhood Hits	467	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

TEX14_MOUSE
NC score	0.052462 (rank : 552)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	319	Target Neighborhood Hits	1333	Shared Neighborhood Hits	97
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DREB_MOUSE
NC score	0.052363 (rank : 553)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	319	Target Neighborhood Hits	446	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

CENPJ_HUMAN
NC score	0.052305 (rank : 554)	θ value	5.27518 (rank : 281)
Query Neighborhood Hits	319	Target Neighborhood Hits	721	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

MACF4_HUMAN
NC score	0.052253 (rank : 555)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	319	Target Neighborhood Hits	1321	Shared Neighborhood Hits	105
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

LCP2_HUMAN
NC score	0.052069 (rank : 556)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	319	Target Neighborhood Hits	531	Shared Neighborhood Hits	51
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

RUFY2_HUMAN
NC score	0.052062 (rank : 557)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	319	Target Neighborhood Hits	1208	Shared Neighborhood Hits	105
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CUTL1_MOUSE
NC score	0.052056 (rank : 558)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	319	Target Neighborhood Hits	1620	Shared Neighborhood Hits	111
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

PLEC1_HUMAN
NC score	0.051703 (rank : 559)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	319	Target Neighborhood Hits	1326	Shared Neighborhood Hits	112
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

NAF1_HUMAN
NC score	0.051626 (rank : 560)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	319	Target Neighborhood Hits	937	Shared Neighborhood Hits	94
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

GCC1_HUMAN
NC score	0.051577 (rank : 561)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	319	Target Neighborhood Hits	887	Shared Neighborhood Hits	89
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

DAAM2_HUMAN
NC score	0.051532 (rank : 562)	θ value	0.62314 (rank : 196)
Query Neighborhood Hits	319	Target Neighborhood Hits	350	Shared Neighborhood Hits	60
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

CYTSA_HUMAN
NC score	0.051501 (rank : 563)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	319	Target Neighborhood Hits	1138	Shared Neighborhood Hits	112
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
NC score	0.051292 (rank : 564)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	319	Target Neighborhood Hits	1104	Shared Neighborhood Hits	108
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

FARP2_HUMAN
NC score	0.051260 (rank : 565)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	319	Target Neighborhood Hits	240	Shared Neighborhood Hits	23
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

SMC3_HUMAN
NC score	0.051259 (rank : 566)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	319	Target Neighborhood Hits	1186	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

PININ_HUMAN
NC score	0.051237 (rank : 567)	θ value	1.38821 (rank : 220)
Query Neighborhood Hits	319	Target Neighborhood Hits	753	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SMC3_MOUSE
NC score	0.051179 (rank : 568)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	319	Target Neighborhood Hits	1187	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

CCD96_HUMAN
NC score	0.051077 (rank : 569)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	319	Target Neighborhood Hits	595	Shared Neighborhood Hits	72
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

DREB_HUMAN
NC score	0.051067 (rank : 570)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	319	Target Neighborhood Hits	450	Shared Neighborhood Hits	56
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

CK5P2_MOUSE
NC score	0.050984 (rank : 571)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	319	Target Neighborhood Hits	1151	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

DDFL1_HUMAN
NC score	0.050787 (rank : 572)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	319	Target Neighborhood Hits	353	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

UACA_MOUSE
NC score	0.050692 (rank : 573)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	319	Target Neighborhood Hits	1620	Shared Neighborhood Hits	122
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

CUTL1_HUMAN
NC score	0.050641 (rank : 574)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	319	Target Neighborhood Hits	1574	Shared Neighborhood Hits	111
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

HIP1_HUMAN
NC score	0.050613 (rank : 575)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	319	Target Neighborhood Hits	1016	Shared Neighborhood Hits	103
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

NRAP_MOUSE
NC score	0.050583 (rank : 576)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	319	Target Neighborhood Hits	167	Shared Neighborhood Hits	21
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

CCD19_HUMAN
NC score	0.050462 (rank : 577)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	319	Target Neighborhood Hits	639	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD96_MOUSE
NC score	0.050453 (rank : 578)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	319	Target Neighborhood Hits	704	Shared Neighborhood Hits	77
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CJ118_MOUSE
NC score	0.050440 (rank : 579)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	319	Target Neighborhood Hits	1132	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CCDC6_HUMAN
NC score	0.050399 (rank : 580)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	319	Target Neighborhood Hits	723	Shared Neighborhood Hits	90
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

BICD2_HUMAN
NC score	0.050391 (rank : 581)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	319	Target Neighborhood Hits	856	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

MACOI_HUMAN
NC score	0.050384 (rank : 582)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	319	Target Neighborhood Hits	650	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

TSC1_HUMAN
NC score	0.050291 (rank : 583)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	319	Target Neighborhood Hits	765	Shared Neighborhood Hits	86
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

EVPL_HUMAN
NC score	0.050203 (rank : 584)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	319	Target Neighborhood Hits	895	Shared Neighborhood Hits	94
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

MACOI_MOUSE
NC score	0.050192 (rank : 585)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	319	Target Neighborhood Hits	620	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

OPTN_HUMAN
NC score	0.050124 (rank : 586)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	319	Target Neighborhood Hits	827	Shared Neighborhood Hits	93
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

FYCO1_HUMAN
NC score	0.050109 (rank : 587)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	319	Target Neighborhood Hits	1149	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FARP1_HUMAN
NC score	0.050102 (rank : 588)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	319	Target Neighborhood Hits	241	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FGD6_HUMAN
NC score	0.050067 (rank : 589)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	319	Target Neighborhood Hits	237	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

SM1L2_MOUSE
NC score	0.050052 (rank : 590)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	319	Target Neighborhood Hits	918	Shared Neighborhood Hits	96
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

TPM1_MOUSE
NC score	0.049699 (rank : 591)	θ value	6.88961 (rank : 293)
Query Neighborhood Hits	319	Target Neighborhood Hits	729	Shared Neighborhood Hits	83
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_HUMAN
NC score	0.049194 (rank : 592)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	319	Target Neighborhood Hits	716	Shared Neighborhood Hits	82
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

NUCB1_MOUSE
NC score	0.048255 (rank : 593)	θ value	2.36792 (rank : 247)
Query Neighborhood Hits	319	Target Neighborhood Hits	414	Shared Neighborhood Hits	69
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

IF31_MOUSE
NC score	0.046554 (rank : 594)	θ value	3.0926 (rank : 256)
Query Neighborhood Hits	319	Target Neighborhood Hits	105	Shared Neighborhood Hits	21
SwissProt Accessions	Q66JS6, Q8BUW6	Gene names	Eif3s1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 1 (eIF-3 alpha).

NCOR2_HUMAN
NC score	0.045486 (rank : 595)	θ value	0.47712 (rank : 190)
Query Neighborhood Hits	319	Target Neighborhood Hits	870	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

HOME1_MOUSE
NC score	0.045075 (rank : 596)	θ value	5.27518 (rank : 282)
Query Neighborhood Hits	319	Target Neighborhood Hits	630	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z2Y3, Q8K3E1, Q8K4M8, Q9Z0E9, Q9Z216	Gene names	Homer1, Vesl1
Domain Architecture
Description	Homer protein homolog 1 (VASP/Ena-related gene up-regulated during seizure and LTP) (Vesl-1).

ROCK1_HUMAN
NC score	0.043860 (rank : 597)	θ value	5.27518 (rank : 284)
Query Neighborhood Hits	319	Target Neighborhood Hits	2000	Shared Neighborhood Hits	141
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

NCOR2_MOUSE
NC score	0.043564 (rank : 598)	θ value	0.813845 (rank : 205)
Query Neighborhood Hits	319	Target Neighborhood Hits	790	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

BPTF_HUMAN
NC score	0.041268 (rank : 599)	θ value	0.0736092 (rank : 153)
Query Neighborhood Hits	319	Target Neighborhood Hits	786	Shared Neighborhood Hits	45
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DAAM2_MOUSE
NC score	0.040265 (rank : 600)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	319	Target Neighborhood Hits	371	Shared Neighborhood Hits	50
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

CCDC7_HUMAN
NC score	0.039082 (rank : 601)	θ value	3.0926 (rank : 252)
Query Neighborhood Hits	319	Target Neighborhood Hits	253	Shared Neighborhood Hits	44
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

M4K4_MOUSE
NC score	0.038932 (rank : 602)	θ value	0.21417 (rank : 175)
Query Neighborhood Hits	319	Target Neighborhood Hits	1560	Shared Neighborhood Hits	107
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

DJC17_HUMAN
NC score	0.034442 (rank : 603)	θ value	0.813845 (rank : 200)
Query Neighborhood Hits	319	Target Neighborhood Hits	335	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NVM6	Gene names	DNAJC17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

M4K4_HUMAN
NC score	0.034409 (rank : 604)	θ value	4.03905 (rank : 276)
Query Neighborhood Hits	319	Target Neighborhood Hits	1589	Shared Neighborhood Hits	112
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

PCQAP_HUMAN
NC score	0.033712 (rank : 605)	θ value	3.0926 (rank : 261)
Query Neighborhood Hits	319	Target Neighborhood Hits	549	Shared Neighborhood Hits	45
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

GGA1_MOUSE
NC score	0.031908 (rank : 606)	θ value	2.36792 (rank : 240)
Query Neighborhood Hits	319	Target Neighborhood Hits	128	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

SFPQ_MOUSE
NC score	0.031483 (rank : 607)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	319	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

NONO_HUMAN
NC score	0.031426 (rank : 608)	θ value	2.36792 (rank : 245)
Query Neighborhood Hits	319	Target Neighborhood Hits	441	Shared Neighborhood Hits	48
SwissProt Accessions	Q15233, O00201, P30807, Q12786, Q9BQC5	Gene names	NONO, NRB54
Domain Architecture
Description	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit).

NONO_MOUSE
NC score	0.031323 (rank : 609)	θ value	2.36792 (rank : 246)
Query Neighborhood Hits	319	Target Neighborhood Hits	444	Shared Neighborhood Hits	48
SwissProt Accessions	Q99K48, Q63887, Q9CYQ4, Q9DBP2	Gene names	Nono
Domain Architecture	No domain graphic available
Description	Non-POU domain-containing octamer-binding protein (NonO protein).

FYV1_MOUSE
NC score	0.030474 (rank : 610)	θ value	0.813845 (rank : 204)
Query Neighborhood Hits	319	Target Neighborhood Hits	191	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

AAT1_HUMAN
NC score	0.029040 (rank : 611)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	319	Target Neighborhood Hits	199	Shared Neighborhood Hits	39
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

FYV1_HUMAN
NC score	0.027734 (rank : 612)	θ value	1.81305 (rank : 227)
Query Neighborhood Hits	319	Target Neighborhood Hits	217	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

K1H2_HUMAN
NC score	0.024964 (rank : 613)	θ value	2.36792 (rank : 242)
Query Neighborhood Hits	319	Target Neighborhood Hits	492	Shared Neighborhood Hits	68
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

USF2_HUMAN
NC score	0.020369 (rank : 614)	θ value	6.88961 (rank : 294)
Query Neighborhood Hits	319	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
NC score	0.020216 (rank : 615)	θ value	6.88961 (rank : 295)
Query Neighborhood Hits	319	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

SP100_HUMAN
NC score	0.015551 (rank : 616)	θ value	1.38821 (rank : 222)
Query Neighborhood Hits	319	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

K1H1_HUMAN
NC score	0.014692 (rank : 617)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	319	Target Neighborhood Hits	433	Shared Neighborhood Hits	61
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

FIBP_HUMAN
NC score	0.012776 (rank : 618)	θ value	4.03905 (rank : 269)
Query Neighborhood Hits	319	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O43427, Q6IBQ3, Q9HD65	Gene names	FIBP
Domain Architecture
Description	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein).

CBP_HUMAN
NC score	0.011627 (rank : 619)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	319	Target Neighborhood Hits	941	Shared Neighborhood Hits	24
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

KIF1A_HUMAN
NC score	0.010153 (rank : 620)	θ value	4.03905 (rank : 273)
Query Neighborhood Hits	319	Target Neighborhood Hits	240	Shared Neighborhood Hits	37
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1A_MOUSE
NC score	0.009821 (rank : 621)	θ value	4.03905 (rank : 274)
Query Neighborhood Hits	319	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

K1H5_HUMAN
NC score	0.009551 (rank : 622)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	319	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q92764, O76012, Q92651	Gene names	KRTHA5, HHA5, HKA5
Domain Architecture
Description	Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5).

TRI18_MOUSE
NC score	0.004355 (rank : 623)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	319	Target Neighborhood Hits	292	Shared Neighborhood Hits	11
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI18_HUMAN
NC score	0.003856 (rank : 624)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	319	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

ZN384_HUMAN
NC score	-0.010336 (rank : 625)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	319	Target Neighborhood Hits	764	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF68, O15407, Q8N938	Gene names	ZNF384, CAGH1, CIZ, NMP4
Domain Architecture	No domain graphic available
Description	Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein).