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Network neighborhood for query Sequence : ARHG1_HUMAN

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ARHG1_HUMAN
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARHG1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	176	Target Neighborhood Hits	176	Shared Neighborhood Hits	176
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
θ value	0 (rank : 2)	NC score	0.969890 (rank : 2)
Query Neighborhood Hits	176	Target Neighborhood Hits	266	Shared Neighborhood Hits	119
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHGC_MOUSE
θ value	8.33966e-147 (rank : 3)	NC score	0.865124 (rank : 3)
Query Neighborhood Hits	176	Target Neighborhood Hits	344	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_HUMAN
θ value	3.41741e-116 (rank : 4)	NC score	0.860930 (rank : 5)
Query Neighborhood Hits	176	Target Neighborhood Hits	351	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGB_HUMAN
θ value	5.14231e-88 (rank : 5)	NC score	0.835875 (rank : 6)
Query Neighborhood Hits	176	Target Neighborhood Hits	375	Shared Neighborhood Hits	74
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

LBC_HUMAN
θ value	8.87376e-48 (rank : 6)	NC score	0.864964 (rank : 4)
Query Neighborhood Hits	176	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

ARHG2_MOUSE
θ value	9.83387e-39 (rank : 7)	NC score	0.831236 (rank : 7)
Query Neighborhood Hits	176	Target Neighborhood Hits	120	Shared Neighborhood Hits	57
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG2_HUMAN
θ value	2.67802e-36 (rank : 8)	NC score	0.819421 (rank : 8)
Query Neighborhood Hits	176	Target Neighborhood Hits	142	Shared Neighborhood Hits	59
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

RGNEF_MOUSE
θ value	1.52067e-31 (rank : 9)	NC score	0.699731 (rank : 12)
Query Neighborhood Hits	176	Target Neighborhood Hits	641	Shared Neighborhood Hits	66
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ITSN2_HUMAN
θ value	1.80048e-24 (rank : 10)	NC score	0.487251 (rank : 43)
Query Neighborhood Hits	176	Target Neighborhood Hits	1173	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN1_HUMAN
θ value	2.35151e-24 (rank : 11)	NC score	0.445117 (rank : 51)
Query Neighborhood Hits	176	Target Neighborhood Hits	1757	Shared Neighborhood Hits	84
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	1.5242e-23 (rank : 12)	NC score	0.444183 (rank : 52)
Query Neighborhood Hits	176	Target Neighborhood Hits	1669	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_MOUSE
θ value	2.59989e-23 (rank : 13)	NC score	0.461273 (rank : 48)
Query Neighborhood Hits	176	Target Neighborhood Hits	1371	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ARHG3_MOUSE
θ value	3.07829e-16 (rank : 14)	NC score	0.720934 (rank : 9)
Query Neighborhood Hits	176	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG8_HUMAN
θ value	3.07829e-16 (rank : 15)	NC score	0.705108 (rank : 11)
Query Neighborhood Hits	176	Target Neighborhood Hits	85	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	5.25075e-16 (rank : 16)	NC score	0.688636 (rank : 14)
Query Neighborhood Hits	176	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHG3_HUMAN
θ value	1.16975e-15 (rank : 17)	NC score	0.720295 (rank : 10)
Query Neighborhood Hits	176	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

FGD4_HUMAN
θ value	3.40345e-15 (rank : 18)	NC score	0.566971 (rank : 27)
Query Neighborhood Hits	176	Target Neighborhood Hits	219	Shared Neighborhood Hits	63
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	4.44505e-15 (rank : 19)	NC score	0.565909 (rank : 28)
Query Neighborhood Hits	176	Target Neighborhood Hits	227	Shared Neighborhood Hits	64
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

ECT2_MOUSE
θ value	3.76295e-14 (rank : 20)	NC score	0.683275 (rank : 15)
Query Neighborhood Hits	176	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

VAV_MOUSE
θ value	3.76295e-14 (rank : 21)	NC score	0.496450 (rank : 39)
Query Neighborhood Hits	176	Target Neighborhood Hits	430	Shared Neighborhood Hits	62
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

NGEF_HUMAN
θ value	6.41864e-14 (rank : 22)	NC score	0.665052 (rank : 19)
Query Neighborhood Hits	176	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

VAV3_MOUSE
θ value	2.43908e-13 (rank : 23)	NC score	0.470769 (rank : 46)
Query Neighborhood Hits	176	Target Neighborhood Hits	404	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

NGEF_MOUSE
θ value	3.18553e-13 (rank : 24)	NC score	0.651711 (rank : 20)
Query Neighborhood Hits	176	Target Neighborhood Hits	228	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

VAV3_HUMAN
θ value	3.18553e-13 (rank : 25)	NC score	0.469540 (rank : 47)
Query Neighborhood Hits	176	Target Neighborhood Hits	398	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	3.18553e-13 (rank : 26)	NC score	0.479894 (rank : 44)
Query Neighborhood Hits	176	Target Neighborhood Hits	452	Shared Neighborhood Hits	61
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ARHGG_MOUSE
θ value	4.16044e-13 (rank : 27)	NC score	0.678401 (rank : 16)
Query Neighborhood Hits	176	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ECT2_HUMAN
θ value	4.16044e-13 (rank : 28)	NC score	0.666632 (rank : 18)
Query Neighborhood Hits	176	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ARHGG_HUMAN
θ value	5.43371e-13 (rank : 29)	NC score	0.689688 (rank : 13)
Query Neighborhood Hits	176	Target Neighborhood Hits	129	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHG5_HUMAN
θ value	9.26847e-13 (rank : 30)	NC score	0.673127 (rank : 17)
Query Neighborhood Hits	176	Target Neighborhood Hits	172	Shared Neighborhood Hits	63
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

FGD2_MOUSE
θ value	2.98157e-11 (rank : 31)	NC score	0.558707 (rank : 29)
Query Neighborhood Hits	176	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_MOUSE
θ value	2.98157e-11 (rank : 32)	NC score	0.590707 (rank : 22)
Query Neighborhood Hits	176	Target Neighborhood Hits	257	Shared Neighborhood Hits	70
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

VAV2_HUMAN
θ value	3.89403e-11 (rank : 33)	NC score	0.493639 (rank : 42)
Query Neighborhood Hits	176	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	3.89403e-11 (rank : 34)	NC score	0.494129 (rank : 40)
Query Neighborhood Hits	176	Target Neighborhood Hits	456	Shared Neighborhood Hits	70
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

FGD2_HUMAN
θ value	5.08577e-11 (rank : 35)	NC score	0.554124 (rank : 30)
Query Neighborhood Hits	176	Target Neighborhood Hits	151	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

ARHGF_HUMAN
θ value	6.64225e-11 (rank : 36)	NC score	0.640509 (rank : 21)
Query Neighborhood Hits	176	Target Neighborhood Hits	214	Shared Neighborhood Hits	65
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

FGD3_HUMAN
θ value	1.47974e-10 (rank : 37)	NC score	0.567839 (rank : 25)
Query Neighborhood Hits	176	Target Neighborhood Hits	249	Shared Neighborhood Hits	82
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

TIAM1_HUMAN
θ value	7.34386e-10 (rank : 38)	NC score	0.567295 (rank : 26)
Query Neighborhood Hits	176	Target Neighborhood Hits	225	Shared Neighborhood Hits	63
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARHGA_HUMAN
θ value	2.79066e-09 (rank : 39)	NC score	0.522562 (rank : 38)
Query Neighborhood Hits	176	Target Neighborhood Hits	187	Shared Neighborhood Hits	58
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

TIAM1_MOUSE
θ value	4.76016e-09 (rank : 40)	NC score	0.575494 (rank : 24)
Query Neighborhood Hits	176	Target Neighborhood Hits	205	Shared Neighborhood Hits	63
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ARHG4_MOUSE
θ value	8.11959e-09 (rank : 41)	NC score	0.549437 (rank : 31)
Query Neighborhood Hits	176	Target Neighborhood Hits	185	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHGA_MOUSE
θ value	8.11959e-09 (rank : 42)	NC score	0.493817 (rank : 41)
Query Neighborhood Hits	176	Target Neighborhood Hits	125	Shared Neighborhood Hits	57
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

FGD1_MOUSE
θ value	1.38499e-08 (rank : 43)	NC score	0.539793 (rank : 35)
Query Neighborhood Hits	176	Target Neighborhood Hits	387	Shared Neighborhood Hits	91
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ARHG9_HUMAN
θ value	5.26297e-08 (rank : 44)	NC score	0.543824 (rank : 32)
Query Neighborhood Hits	176	Target Neighborhood Hits	235	Shared Neighborhood Hits	61
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	5.26297e-08 (rank : 45)	NC score	0.543209 (rank : 34)
Query Neighborhood Hits	176	Target Neighborhood Hits	234	Shared Neighborhood Hits	61
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

PREX1_HUMAN
θ value	6.87365e-08 (rank : 46)	NC score	0.582169 (rank : 23)
Query Neighborhood Hits	176	Target Neighborhood Hits	177	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

ARHG4_HUMAN
θ value	8.97725e-08 (rank : 47)	NC score	0.523695 (rank : 37)
Query Neighborhood Hits	176	Target Neighborhood Hits	242	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

FGD1_HUMAN
θ value	8.97725e-08 (rank : 48)	NC score	0.534173 (rank : 36)
Query Neighborhood Hits	176	Target Neighborhood Hits	367	Shared Neighborhood Hits	87
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PKHG1_HUMAN
θ value	8.97725e-08 (rank : 49)	NC score	0.543788 (rank : 33)
Query Neighborhood Hits	176	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

FGD6_HUMAN
θ value	3.41135e-07 (rank : 50)	NC score	0.456526 (rank : 49)
Query Neighborhood Hits	176	Target Neighborhood Hits	237	Shared Neighborhood Hits	61
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	3.41135e-07 (rank : 51)	NC score	0.456468 (rank : 50)
Query Neighborhood Hits	176	Target Neighborhood Hits	282	Shared Neighborhood Hits	60
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

DNMBP_HUMAN
θ value	2.44474e-05 (rank : 52)	NC score	0.419746 (rank : 55)
Query Neighborhood Hits	176	Target Neighborhood Hits	413	Shared Neighborhood Hits	67
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

MCF2_HUMAN
θ value	0.000121331 (rank : 53)	NC score	0.476256 (rank : 45)
Query Neighborhood Hits	176	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

DNMBP_MOUSE
θ value	0.00035302 (rank : 54)	NC score	0.426799 (rank : 54)
Query Neighborhood Hits	176	Target Neighborhood Hits	435	Shared Neighborhood Hits	66
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FGD5_HUMAN
θ value	0.00102713 (rank : 55)	NC score	0.337640 (rank : 57)
Query Neighborhood Hits	176	Target Neighborhood Hits	235	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

HRX_HUMAN
θ value	0.00102713 (rank : 56)	NC score	0.047362 (rank : 319)
Query Neighborhood Hits	176	Target Neighborhood Hits	825	Shared Neighborhood Hits	37
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MCF2L_MOUSE
θ value	0.00665767 (rank : 57)	NC score	0.440452 (rank : 53)
Query Neighborhood Hits	176	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

FGD5_MOUSE
θ value	0.0113563 (rank : 58)	NC score	0.313089 (rank : 60)
Query Neighborhood Hits	176	Target Neighborhood Hits	170	Shared Neighborhood Hits	43
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

CO8A1_HUMAN
θ value	0.0148317 (rank : 59)	NC score	0.092314 (rank : 107)
Query Neighborhood Hits	176	Target Neighborhood Hits	288	Shared Neighborhood Hits	59
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

CO4A5_HUMAN
θ value	0.0330416 (rank : 60)	NC score	0.092463 (rank : 106)
Query Neighborhood Hits	176	Target Neighborhood Hits	383	Shared Neighborhood Hits	68
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO8A1_MOUSE
θ value	0.0330416 (rank : 61)	NC score	0.090825 (rank : 111)
Query Neighborhood Hits	176	Target Neighborhood Hits	251	Shared Neighborhood Hits	58
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

DUET_HUMAN
θ value	0.0431538 (rank : 62)	NC score	0.158919 (rank : 71)
Query Neighborhood Hits	176	Target Neighborhood Hits	1220	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

CO5A2_HUMAN
θ value	0.0736092 (rank : 63)	NC score	0.082147 (rank : 155)
Query Neighborhood Hits	176	Target Neighborhood Hits	760	Shared Neighborhood Hits	65
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

DDX51_HUMAN
θ value	0.0961366 (rank : 64)	NC score	0.014948 (rank : 355)
Query Neighborhood Hits	176	Target Neighborhood Hits	332	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

CO6A2_HUMAN
θ value	0.125558 (rank : 65)	NC score	0.086367 (rank : 134)
Query Neighborhood Hits	176	Target Neighborhood Hits	249	Shared Neighborhood Hits	62
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

OGFR_MOUSE
θ value	0.125558 (rank : 66)	NC score	0.082066 (rank : 157)
Query Neighborhood Hits	176	Target Neighborhood Hits	584	Shared Neighborhood Hits	70
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

N4BP2_HUMAN
θ value	0.163984 (rank : 67)	NC score	0.053191 (rank : 293)
Query Neighborhood Hits	176	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

TRIO_HUMAN
θ value	0.163984 (rank : 68)	NC score	0.147053 (rank : 72)
Query Neighborhood Hits	176	Target Neighborhood Hits	1580	Shared Neighborhood Hits	83
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

HAPIP_HUMAN
θ value	0.21417 (rank : 69)	NC score	0.348041 (rank : 56)
Query Neighborhood Hits	176	Target Neighborhood Hits	350	Shared Neighborhood Hits	67
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

CO5A1_MOUSE
θ value	0.279714 (rank : 70)	NC score	0.094909 (rank : 102)
Query Neighborhood Hits	176	Target Neighborhood Hits	419	Shared Neighborhood Hits	64
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

ABR_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.261058 (rank : 70)
Query Neighborhood Hits	176	Target Neighborhood Hits	166	Shared Neighborhood Hits	56
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

BCR_HUMAN
θ value	0.365318 (rank : 72)	NC score	0.268685 (rank : 67)
Query Neighborhood Hits	176	Target Neighborhood Hits	204	Shared Neighborhood Hits	55
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CO1A1_HUMAN
θ value	0.365318 (rank : 73)	NC score	0.086067 (rank : 136)
Query Neighborhood Hits	176	Target Neighborhood Hits	475	Shared Neighborhood Hits	65
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO9A1_MOUSE
θ value	0.365318 (rank : 74)	NC score	0.079545 (rank : 171)
Query Neighborhood Hits	176	Target Neighborhood Hits	477	Shared Neighborhood Hits	61
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CP250_HUMAN
θ value	0.365318 (rank : 75)	NC score	0.042040 (rank : 323)
Query Neighborhood Hits	176	Target Neighborhood Hits	1805	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

BAZ2A_MOUSE
θ value	0.47712 (rank : 76)	NC score	0.020249 (rank : 346)
Query Neighborhood Hits	176	Target Neighborhood Hits	744	Shared Neighborhood Hits	27
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CO4A6_HUMAN
θ value	0.47712 (rank : 77)	NC score	0.083650 (rank : 148)
Query Neighborhood Hits	176	Target Neighborhood Hits	318	Shared Neighborhood Hits	60
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

TITIN_HUMAN
θ value	0.47712 (rank : 78)	NC score	0.004069 (rank : 372)
Query Neighborhood Hits	176	Target Neighborhood Hits	2923	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

COBA2_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.085707 (rank : 141)
Query Neighborhood Hits	176	Target Neighborhood Hits	501	Shared Neighborhood Hits	64
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COEA1_MOUSE
θ value	0.62314 (rank : 80)	NC score	0.051121 (rank : 315)
Query Neighborhood Hits	176	Target Neighborhood Hits	402	Shared Neighborhood Hits	60
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

SRRM2_MOUSE
θ value	0.62314 (rank : 81)	NC score	0.042590 (rank : 322)
Query Neighborhood Hits	176	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CO4A2_HUMAN
θ value	0.813845 (rank : 82)	NC score	0.088213 (rank : 122)
Query Neighborhood Hits	176	Target Neighborhood Hits	454	Shared Neighborhood Hits	64
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO5A3_HUMAN
θ value	0.813845 (rank : 83)	NC score	0.086334 (rank : 135)
Query Neighborhood Hits	176	Target Neighborhood Hits	433	Shared Neighborhood Hits	64
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

COBA2_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.087138 (rank : 129)
Query Neighborhood Hits	176	Target Neighborhood Hits	408	Shared Neighborhood Hits	63
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COJA1_HUMAN
θ value	0.813845 (rank : 85)	NC score	0.081397 (rank : 164)
Query Neighborhood Hits	176	Target Neighborhood Hits	323	Shared Neighborhood Hits	60
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

MAGC1_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.019982 (rank : 347)
Query Neighborhood Hits	176	Target Neighborhood Hits	431	Shared Neighborhood Hits	23
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

RB6I2_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.030222 (rank : 333)
Query Neighborhood Hits	176	Target Neighborhood Hits	1584	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.031914 (rank : 332)
Query Neighborhood Hits	176	Target Neighborhood Hits	1433	Shared Neighborhood Hits	29
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SYNE2_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.029865 (rank : 334)
Query Neighborhood Hits	176	Target Neighborhood Hits	1323	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TGON2_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.022926 (rank : 338)
Query Neighborhood Hits	176	Target Neighborhood Hits	1037	Shared Neighborhood Hits	46
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

BPA1_MOUSE
θ value	1.06291 (rank : 91)	NC score	0.022890 (rank : 339)
Query Neighborhood Hits	176	Target Neighborhood Hits	1477	Shared Neighborhood Hits	34
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CO5A1_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.091936 (rank : 109)
Query Neighborhood Hits	176	Target Neighborhood Hits	434	Shared Neighborhood Hits	65
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO6A2_MOUSE
θ value	1.06291 (rank : 93)	NC score	0.087793 (rank : 126)
Query Neighborhood Hits	176	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

COBA1_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.088035 (rank : 124)
Query Neighborhood Hits	176	Target Neighborhood Hits	487	Shared Neighborhood Hits	68
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CT151_HUMAN
θ value	1.06291 (rank : 95)	NC score	0.032332 (rank : 330)
Query Neighborhood Hits	176	Target Neighborhood Hits	382	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

KCD12_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.014636 (rank : 357)
Query Neighborhood Hits	176	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

CO1A1_MOUSE
θ value	1.38821 (rank : 97)	NC score	0.085445 (rank : 143)
Query Neighborhood Hits	176	Target Neighborhood Hits	457	Shared Neighborhood Hits	67
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A2_HUMAN
θ value	1.38821 (rank : 98)	NC score	0.081822 (rank : 162)
Query Neighborhood Hits	176	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO3A1_MOUSE
θ value	1.38821 (rank : 99)	NC score	0.085969 (rank : 138)
Query Neighborhood Hits	176	Target Neighborhood Hits	466	Shared Neighborhood Hits	65
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO8A2_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.089797 (rank : 116)
Query Neighborhood Hits	176	Target Neighborhood Hits	299	Shared Neighborhood Hits	65
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CP250_MOUSE
θ value	1.38821 (rank : 101)	NC score	0.039986 (rank : 324)
Query Neighborhood Hits	176	Target Neighborhood Hits	1583	Shared Neighborhood Hits	35
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

IP3KC_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.015716 (rank : 352)
Query Neighborhood Hits	176	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

MINT_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.032770 (rank : 329)
Query Neighborhood Hits	176	Target Neighborhood Hits	1514	Shared Neighborhood Hits	52
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

OGFR_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.057692 (rank : 257)
Query Neighborhood Hits	176	Target Neighborhood Hits	1582	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RXRA_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.002979 (rank : 373)
Query Neighborhood Hits	176	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

SENP1_MOUSE
θ value	1.38821 (rank : 106)	NC score	0.014235 (rank : 359)
Query Neighborhood Hits	176	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

TXND2_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.025635 (rank : 337)
Query Neighborhood Hits	176	Target Neighborhood Hits	793	Shared Neighborhood Hits	28
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CO3A1_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.085739 (rank : 140)
Query Neighborhood Hits	176	Target Neighborhood Hits	452	Shared Neighborhood Hits	67
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A2_MOUSE
θ value	1.81305 (rank : 109)	NC score	0.086023 (rank : 137)
Query Neighborhood Hits	176	Target Neighborhood Hits	492	Shared Neighborhood Hits	65
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO6A1_HUMAN
θ value	1.81305 (rank : 110)	NC score	0.076226 (rank : 180)
Query Neighborhood Hits	176	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO9A3_HUMAN
θ value	1.81305 (rank : 111)	NC score	0.078663 (rank : 174)
Query Neighborhood Hits	176	Target Neighborhood Hits	361	Shared Neighborhood Hits	60
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COBA1_HUMAN
θ value	1.81305 (rank : 112)	NC score	0.088179 (rank : 123)
Query Neighborhood Hits	176	Target Neighborhood Hits	491	Shared Neighborhood Hits	67
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

DMRTD_HUMAN
θ value	1.81305 (rank : 113)	NC score	0.015679 (rank : 353)
Query Neighborhood Hits	176	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

BSN_MOUSE
θ value	2.36792 (rank : 114)	NC score	0.036098 (rank : 328)
Query Neighborhood Hits	176	Target Neighborhood Hits	2057	Shared Neighborhood Hits	86
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CONA1_MOUSE
θ value	2.36792 (rank : 115)	NC score	0.089737 (rank : 117)
Query Neighborhood Hits	176	Target Neighborhood Hits	254	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

LIPS_HUMAN
θ value	2.36792 (rank : 116)	NC score	0.019034 (rank : 348)
Query Neighborhood Hits	176	Target Neighborhood Hits	314	Shared Neighborhood Hits	18
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MLL2_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.056077 (rank : 269)
Query Neighborhood Hits	176	Target Neighborhood Hits	1788	Shared Neighborhood Hits	92
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SFTPA_MOUSE
θ value	2.36792 (rank : 118)	NC score	0.052520 (rank : 300)
Query Neighborhood Hits	176	Target Neighborhood Hits	169	Shared Neighborhood Hits	47
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

STAR8_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.011823 (rank : 361)
Query Neighborhood Hits	176	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

C1QA_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.062276 (rank : 231)
Query Neighborhood Hits	176	Target Neighborhood Hits	116	Shared Neighborhood Hits	49
SwissProt Accessions	P98086	Gene names	C1qa
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

CO2A1_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.084478 (rank : 145)
Query Neighborhood Hits	176	Target Neighborhood Hits	486	Shared Neighborhood Hits	69
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.081500 (rank : 163)
Query Neighborhood Hits	176	Target Neighborhood Hits	483	Shared Neighborhood Hits	65
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO7A1_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.070140 (rank : 202)
Query Neighborhood Hits	176	Target Neighborhood Hits	807	Shared Neighborhood Hits	65
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO8A2_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.083243 (rank : 150)
Query Neighborhood Hits	176	Target Neighborhood Hits	273	Shared Neighborhood Hits	59
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CO9A2_MOUSE
θ value	3.0926 (rank : 125)	NC score	0.082262 (rank : 152)
Query Neighborhood Hits	176	Target Neighborhood Hits	279	Shared Neighborhood Hits	61
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COAA1_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.077450 (rank : 178)
Query Neighborhood Hits	176	Target Neighborhood Hits	316	Shared Neighborhood Hits	62
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COEA1_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.056093 (rank : 268)
Query Neighborhood Hits	176	Target Neighborhood Hits	427	Shared Neighborhood Hits	62
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CT175_HUMAN
θ value	3.0926 (rank : 128)	NC score	0.020707 (rank : 343)
Query Neighborhood Hits	176	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MK2, Q5QPB6, Q9NQQ2	Gene names	C20orf175
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf175.

DNM1L_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.007617 (rank : 367)
Query Neighborhood Hits	176	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

SET1A_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.031999 (rank : 331)
Query Neighborhood Hits	176	Target Neighborhood Hits	690	Shared Neighborhood Hits	25
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TP53B_HUMAN
θ value	3.0926 (rank : 131)	NC score	0.014380 (rank : 358)
Query Neighborhood Hits	176	Target Neighborhood Hits	413	Shared Neighborhood Hits	15
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CEP55_MOUSE
θ value	4.03905 (rank : 132)	NC score	0.029360 (rank : 335)
Query Neighborhood Hits	176	Target Neighborhood Hits	693	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CO4A1_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.083225 (rank : 151)
Query Neighborhood Hits	176	Target Neighborhood Hits	425	Shared Neighborhood Hits	65
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COGA1_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.082250 (rank : 153)
Query Neighborhood Hits	176	Target Neighborhood Hits	345	Shared Neighborhood Hits	62
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CONA1_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.084504 (rank : 144)
Query Neighborhood Hits	176	Target Neighborhood Hits	281	Shared Neighborhood Hits	63
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

NCOA5_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.020845 (rank : 341)
Query Neighborhood Hits	176	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

PO3F2_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.004498 (rank : 371)
Query Neighborhood Hits	176	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	P31360	Gene names	Pou3f2, Brn-2, Brn2, Otf7
Domain Architecture
Description	POU domain, class 3, transcription factor 2 (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Protein Brn-2).

SAPS1_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.020257 (rank : 345)
Query Neighborhood Hits	176	Target Neighborhood Hits	704	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CGRE1_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.042680 (rank : 321)
Query Neighborhood Hits	176	Target Neighborhood Hits	354	Shared Neighborhood Hits	56
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CHIC1_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.011228 (rank : 362)
Query Neighborhood Hits	176	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CBW7, O08904, Q8K3S5	Gene names	Chic1, Brx
Domain Architecture	No domain graphic available
Description	Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein).

CI039_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.027334 (rank : 336)
Query Neighborhood Hits	176	Target Neighborhood Hits	1171	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CO4A1_MOUSE
θ value	5.27518 (rank : 142)	NC score	0.084009 (rank : 147)
Query Neighborhood Hits	176	Target Neighborhood Hits	450	Shared Neighborhood Hits	65
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO9A1_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.076383 (rank : 179)
Query Neighborhood Hits	176	Target Neighborhood Hits	420	Shared Neighborhood Hits	60
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COHA1_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.075252 (rank : 184)
Query Neighborhood Hits	176	Target Neighborhood Hits	400	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

FA13C_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.015740 (rank : 351)
Query Neighborhood Hits	176	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FMNL_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.017217 (rank : 350)
Query Neighborhood Hits	176	Target Neighborhood Hits	428	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GNAS3_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.021969 (rank : 340)
Query Neighborhood Hits	176	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

GOPC_HUMAN
θ value	5.27518 (rank : 148)	NC score	0.043612 (rank : 320)
Query Neighborhood Hits	176	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

MA2A1_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.007487 (rank : 368)
Query Neighborhood Hits	176	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

MDN1_HUMAN
θ value	5.27518 (rank : 150)	NC score	0.014863 (rank : 356)
Query Neighborhood Hits	176	Target Neighborhood Hits	662	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

SRBS1_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.128512 (rank : 80)
Query Neighborhood Hits	176	Target Neighborhood Hits	396	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CO1A2_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.080044 (rank : 168)
Query Neighborhood Hits	176	Target Neighborhood Hits	388	Shared Neighborhood Hits	62
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A4_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.079269 (rank : 172)
Query Neighborhood Hits	176	Target Neighborhood Hits	440	Shared Neighborhood Hits	67
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO9A2_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.077851 (rank : 177)
Query Neighborhood Hits	176	Target Neighborhood Hits	261	Shared Neighborhood Hits	58
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

DLGP4_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.007329 (rank : 369)
Query Neighborhood Hits	176	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

HIC1_MOUSE
θ value	6.88961 (rank : 156)	NC score	-0.005156 (rank : 376)
Query Neighborhood Hits	176	Target Neighborhood Hits	863	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

KCD12_MOUSE
θ value	6.88961 (rank : 157)	NC score	0.010337 (rank : 363)
Query Neighborhood Hits	176	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WVG3	Gene names	Kctd12, Pfet1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

MARCO_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.063490 (rank : 226)
Query Neighborhood Hits	176	Target Neighborhood Hits	199	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

MARCO_MOUSE
θ value	6.88961 (rank : 159)	NC score	0.071501 (rank : 199)
Query Neighborhood Hits	176	Target Neighborhood Hits	242	Shared Neighborhood Hits	57
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

MED12_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.038665 (rank : 325)
Query Neighborhood Hits	176	Target Neighborhood Hits	262	Shared Neighborhood Hits	11
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

RGS3_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.054746 (rank : 282)
Query Neighborhood Hits	176	Target Neighborhood Hits	1375	Shared Neighborhood Hits	85
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ROBO1_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.002037 (rank : 374)
Query Neighborhood Hits	176	Target Neighborhood Hits	529	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

RTN1_HUMAN
θ value	6.88961 (rank : 163)	NC score	0.012792 (rank : 360)
Query Neighborhood Hits	176	Target Neighborhood Hits	173	Shared Neighborhood Hits	21
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

RTN4_MOUSE
θ value	6.88961 (rank : 164)	NC score	0.009132 (rank : 364)
Query Neighborhood Hits	176	Target Neighborhood Hits	341	Shared Neighborhood Hits	12
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

TCP10_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.015134 (rank : 354)
Query Neighborhood Hits	176	Target Neighborhood Hits	134	Shared Neighborhood Hits	17
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

C1QT5_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.057795 (rank : 255)
Query Neighborhood Hits	176	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXJ0, Q8N6P2, Q9UFX4	Gene names	C1QTNF5, CTRP5
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

CK042_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.020284 (rank : 344)
Query Neighborhood Hits	176	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5U0	Gene names	C11orf42
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf42.

MELPH_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.020782 (rank : 342)
Query Neighborhood Hits	176	Target Neighborhood Hits	145	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

MTSS1_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.036180 (rank : 327)
Query Neighborhood Hits	176	Target Neighborhood Hits	592	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PITM3_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.008420 (rank : 366)
Query Neighborhood Hits	176	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

RBBP6_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.006826 (rank : 370)
Query Neighborhood Hits	176	Target Neighborhood Hits	1135	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

REXO1_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.008477 (rank : 365)
Query Neighborhood Hits	176	Target Neighborhood Hits	242	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RFIP3_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.038426 (rank : 326)
Query Neighborhood Hits	176	Target Neighborhood Hits	1055	Shared Neighborhood Hits	43
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SCAR3_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.068675 (rank : 208)
Query Neighborhood Hits	176	Target Neighborhood Hits	205	Shared Neighborhood Hits	56
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

SCN5A_HUMAN
θ value	8.99809 (rank : 175)	NC score	0.001161 (rank : 375)
Query Neighborhood Hits	176	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SYBU_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.017709 (rank : 349)
Query Neighborhood Hits	176	Target Neighborhood Hits	214	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

ABI1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.081925 (rank : 160)
Query Neighborhood Hits	176	Target Neighborhood Hits	257	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ABI1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.087067 (rank : 130)
Query Neighborhood Hits	176	Target Neighborhood Hits	246	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.090831 (rank : 110)
Query Neighborhood Hits	176	Target Neighborhood Hits	350	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.089851 (rank : 115)
Query Neighborhood Hits	176	Target Neighborhood Hits	266	Shared Neighborhood Hits	23
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ABI3_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.076208 (rank : 181)
Query Neighborhood Hits	176	Target Neighborhood Hits	227	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ABI3_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.074754 (rank : 189)
Query Neighborhood Hits	176	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

ADIPO_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.056702 (rank : 264)
Query Neighborhood Hits	176	Target Neighborhood Hits	169	Shared Neighborhood Hits	52
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

ADIPO_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.058852 (rank : 244)
Query Neighborhood Hits	176	Target Neighborhood Hits	182	Shared Neighborhood Hits	52
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

AHI1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.074611 (rank : 190)
Query Neighborhood Hits	176	Target Neighborhood Hits	537	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.073231 (rank : 195)
Query Neighborhood Hits	176	Target Neighborhood Hits	496	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ANM2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.064295 (rank : 222)
Query Neighborhood Hits	176	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.060635 (rank : 236)
Query Neighborhood Hits	176	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARHG6_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.287165 (rank : 64)
Query Neighborhood Hits	176	Target Neighborhood Hits	376	Shared Neighborhood Hits	52
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

ARHG6_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.266299 (rank : 68)
Query Neighborhood Hits	176	Target Neighborhood Hits	394	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG7_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.320794 (rank : 59)
Query Neighborhood Hits	176	Target Neighborhood Hits	347	Shared Neighborhood Hits	61
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

ARHG7_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.300346 (rank : 63)
Query Neighborhood Hits	176	Target Neighborhood Hits	396	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

BAIP2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.065016 (rank : 220)
Query Neighborhood Hits	176	Target Neighborhood Hits	192	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BAIP2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.065942 (rank : 217)
Query Neighborhood Hits	176	Target Neighborhood Hits	185	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BCAR1_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.058723 (rank : 245)
Query Neighborhood Hits	176	Target Neighborhood Hits	554	Shared Neighborhood Hits	32
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCAR1_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.060694 (rank : 235)
Query Neighborhood Hits	176	Target Neighborhood Hits	438	Shared Neighborhood Hits	26
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BI2L1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.087659 (rank : 127)
Query Neighborhood Hits	176	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BI2L1_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.072398 (rank : 198)
Query Neighborhood Hits	176	Target Neighborhood Hits	197	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

C1QA_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.057454 (rank : 258)
Query Neighborhood Hits	176	Target Neighborhood Hits	179	Shared Neighborhood Hits	51
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

C1QB_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.057260 (rank : 259)
Query Neighborhood Hits	176	Target Neighborhood Hits	126	Shared Neighborhood Hits	49
SwissProt Accessions	P02746, Q5T959, Q96H17	Gene names	C1QB
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

C1QB_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.058357 (rank : 249)
Query Neighborhood Hits	176	Target Neighborhood Hits	126	Shared Neighborhood Hits	51
SwissProt Accessions	P14106	Gene names	C1qb
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

C1QC_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.056517 (rank : 265)
Query Neighborhood Hits	176	Target Neighborhood Hits	124	Shared Neighborhood Hits	48
SwissProt Accessions	P02747, Q7Z502, Q96DL2, Q96H05	Gene names	C1QC, C1QG
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

C1QC_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.057023 (rank : 261)
Query Neighborhood Hits	176	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

C1QT2_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.059429 (rank : 240)
Query Neighborhood Hits	176	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXJ5	Gene names	C1QTNF2, CTRP2
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 2 precursor.

C1QT5_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.055241 (rank : 278)
Query Neighborhood Hits	176	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

C1QT7_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.058034 (rank : 253)
Query Neighborhood Hits	176	Target Neighborhood Hits	119	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BXJ2	Gene names	C1QTNF7, CTRP7
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

C1QT7_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.059462 (rank : 239)
Query Neighborhood Hits	176	Target Neighborhood Hits	124	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BVD7, Q8CHX9	Gene names	C1qtnf7, Ctrp7
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

CASL_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.060944 (rank : 234)
Query Neighborhood Hits	176	Target Neighborhood Hits	259	Shared Neighborhood Hits	28
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CASL_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.055492 (rank : 275)
Query Neighborhood Hits	176	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CD2AP_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.131221 (rank : 79)
Query Neighborhood Hits	176	Target Neighborhood Hits	315	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.132541 (rank : 76)
Query Neighborhood Hits	176	Target Neighborhood Hits	336	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CO4A3_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.081378 (rank : 165)
Query Neighborhood Hits	176	Target Neighborhood Hits	421	Shared Neighborhood Hits	65
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO6A1_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.074955 (rank : 186)
Query Neighborhood Hits	176	Target Neighborhood Hits	241	Shared Neighborhood Hits	58
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A3_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.053885 (rank : 288)
Query Neighborhood Hits	176	Target Neighborhood Hits	317	Shared Neighborhood Hits	58
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

COAA1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.072752 (rank : 197)
Query Neighborhood Hits	176	Target Neighborhood Hits	286	Shared Neighborhood Hits	58
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COFA1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.057770 (rank : 256)
Query Neighborhood Hits	176	Target Neighborhood Hits	292	Shared Neighborhood Hits	58
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

COFA1_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.059889 (rank : 238)
Query Neighborhood Hits	176	Target Neighborhood Hits	305	Shared Neighborhood Hits	60
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

COHA1_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.075210 (rank : 185)
Query Neighborhood Hits	176	Target Neighborhood Hits	414	Shared Neighborhood Hits	64
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COIA1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.066796 (rank : 214)
Query Neighborhood Hits	176	Target Neighborhood Hits	447	Shared Neighborhood Hits	65
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COIA1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.067100 (rank : 211)
Query Neighborhood Hits	176	Target Neighborhood Hits	481	Shared Neighborhood Hits	67
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COLQ_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.069117 (rank : 206)
Query Neighborhood Hits	176	Target Neighborhood Hits	193	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

CRKL_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.091988 (rank : 108)
Query Neighborhood Hits	176	Target Neighborhood Hits	313	Shared Neighborhood Hits	18
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CRKL_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.089297 (rank : 119)
Query Neighborhood Hits	176	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CRK_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.079832 (rank : 170)
Query Neighborhood Hits	176	Target Neighborhood Hits	308	Shared Neighborhood Hits	18
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.082147 (rank : 156)
Query Neighborhood Hits	176	Target Neighborhood Hits	314	Shared Neighborhood Hits	19
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CT032_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.059094 (rank : 243)
Query Neighborhood Hits	176	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

CTHR1_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.052327 (rank : 302)
Query Neighborhood Hits	176	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.052240 (rank : 304)
Query Neighborhood Hits	176	Target Neighborhood Hits	123	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

DBNL_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.074215 (rank : 192)
Query Neighborhood Hits	176	Target Neighborhood Hits	244	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.069988 (rank : 203)
Query Neighborhood Hits	176	Target Neighborhood Hits	306	Shared Neighborhood Hits	24
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

EDA_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.053930 (rank : 287)
Query Neighborhood Hits	176	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EDA_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.053367 (rank : 292)
Query Neighborhood Hits	176	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EFS_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.056117 (rank : 266)
Query Neighborhood Hits	176	Target Neighborhood Hits	348	Shared Neighborhood Hits	23
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EFS_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.059255 (rank : 241)
Query Neighborhood Hits	176	Target Neighborhood Hits	389	Shared Neighborhood Hits	26
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

EHD1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.052779 (rank : 296)
Query Neighborhood Hits	176	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4M9, O14611, Q9UNR3	Gene names	EHD1, PAST, PAST1
Domain Architecture
Description	EH-domain-containing protein 1 (Testilin) (hPAST1).

EHD1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.052691 (rank : 297)
Query Neighborhood Hits	176	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVK4	Gene names	Ehd1, Past1
Domain Architecture
Description	EH-domain-containing protein 1 (mPAST1).

EHD2_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.052171 (rank : 306)
Query Neighborhood Hits	176	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN4, Q96CB6	Gene names	EHD2
Domain Architecture
Description	EH-domain-containing protein 2.

EHD3_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.052075 (rank : 307)
Query Neighborhood Hits	176	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN3, Q8N514, Q9NZB3	Gene names	EHD3, EHD2
Domain Architecture
Description	EH-domain-containing protein 3.

EHD3_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.051699 (rank : 310)
Query Neighborhood Hits	176	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXY6	Gene names	Ehd3, Ehd2
Domain Architecture
Description	EH-domain-containing protein 3.

EHD4_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.051482 (rank : 313)
Query Neighborhood Hits	176	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQP2	Gene names	Ehd4, Past2
Domain Architecture
Description	EH-domain-containing protein 4 (mPAST2).

ELN_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.054978 (rank : 281)
Query Neighborhood Hits	176	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

EMID1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.058401 (rank : 248)
Query Neighborhood Hits	176	Target Neighborhood Hits	215	Shared Neighborhood Hits	56
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EMID1_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.066909 (rank : 213)
Query Neighborhood Hits	176	Target Neighborhood Hits	230	Shared Neighborhood Hits	59
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EMID2_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.056776 (rank : 263)
Query Neighborhood Hits	176	Target Neighborhood Hits	226	Shared Neighborhood Hits	54
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EMID2_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.052186 (rank : 305)
Query Neighborhood Hits	176	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EP15R_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.051810 (rank : 309)
Query Neighborhood Hits	176	Target Neighborhood Hits	1083	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.056104 (rank : 267)
Query Neighborhood Hits	176	Target Neighborhood Hits	1135	Shared Neighborhood Hits	28
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.052253 (rank : 303)
Query Neighborhood Hits	176	Target Neighborhood Hits	1021	Shared Neighborhood Hits	26
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.052339 (rank : 301)
Query Neighborhood Hits	176	Target Neighborhood Hits	820	Shared Neighborhood Hits	18
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

FARP1_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.276813 (rank : 66)
Query Neighborhood Hits	176	Target Neighborhood Hits	241	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.281058 (rank : 65)
Query Neighborhood Hits	176	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.311448 (rank : 61)
Query Neighborhood Hits	176	Target Neighborhood Hits	209	Shared Neighborhood Hits	60
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FYV1_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.050518 (rank : 317)
Query Neighborhood Hits	176	Target Neighborhood Hits	217	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

GLDN_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.055778 (rank : 274)
Query Neighborhood Hits	176	Target Neighborhood Hits	159	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

GLDN_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.055854 (rank : 273)
Query Neighborhood Hits	176	Target Neighborhood Hits	155	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

GNRP_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.305670 (rank : 62)
Query Neighborhood Hits	176	Target Neighborhood Hits	239	Shared Neighborhood Hits	52
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.326211 (rank : 58)
Query Neighborhood Hits	176	Target Neighborhood Hits	191	Shared Neighborhood Hits	53
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GRAP2_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.088367 (rank : 121)
Query Neighborhood Hits	176	Target Neighborhood Hits	304	Shared Neighborhood Hits	18
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.087989 (rank : 125)
Query Neighborhood Hits	176	Target Neighborhood Hits	297	Shared Neighborhood Hits	18
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.115831 (rank : 92)
Query Neighborhood Hits	176	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.114578 (rank : 93)
Query Neighborhood Hits	176	Target Neighborhood Hits	309	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.101270 (rank : 98)
Query Neighborhood Hits	176	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.101175 (rank : 99)
Query Neighborhood Hits	176	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HCLS1_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.090065 (rank : 114)
Query Neighborhood Hits	176	Target Neighborhood Hits	358	Shared Neighborhood Hits	28
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.090765 (rank : 112)
Query Neighborhood Hits	176	Target Neighborhood Hits	329	Shared Neighborhood Hits	26
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HGS_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.074764 (rank : 188)
Query Neighborhood Hits	176	Target Neighborhood Hits	517	Shared Neighborhood Hits	25
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.074793 (rank : 187)
Query Neighborhood Hits	176	Target Neighborhood Hits	589	Shared Neighborhood Hits	29
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

IASPP_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.052588 (rank : 299)
Query Neighborhood Hits	176	Target Neighborhood Hits	688	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IASPP_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.061957 (rank : 232)
Query Neighborhood Hits	176	Target Neighborhood Hits	1024	Shared Neighborhood Hits	73
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LASP1_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.070700 (rank : 201)
Query Neighborhood Hits	176	Target Neighborhood Hits	293	Shared Neighborhood Hits	20
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.068402 (rank : 209)
Query Neighborhood Hits	176	Target Neighborhood Hits	297	Shared Neighborhood Hits	20
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LMO7_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.058329 (rank : 250)
Query Neighborhood Hits	176	Target Neighborhood Hits	507	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MIA_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.054080 (rank : 286)
Query Neighborhood Hits	176	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q16674	Gene names	MIA
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity).

MIA_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.054211 (rank : 285)
Query Neighborhood Hits	176	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q61865, O09086, P97495	Gene names	Mia, Cdrap, Mia1
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity) (Cartilage-derived retinoic acid-sensitive protein) (CD-RAP).

MSRE_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.051482 (rank : 312)
Query Neighborhood Hits	176	Target Neighborhood Hits	298	Shared Neighborhood Hits	57
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

NCF1_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.136089 (rank : 74)
Query Neighborhood Hits	176	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF1_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.131266 (rank : 78)
Query Neighborhood Hits	176	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NCF2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.124689 (rank : 83)
Query Neighborhood Hits	176	Target Neighborhood Hits	229	Shared Neighborhood Hits	22
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCF4_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.100712 (rank : 100)
Query Neighborhood Hits	176	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.100378 (rank : 101)
Query Neighborhood Hits	176	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK1_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.116529 (rank : 91)
Query Neighborhood Hits	176	Target Neighborhood Hits	312	Shared Neighborhood Hits	23
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.113095 (rank : 94)
Query Neighborhood Hits	176	Target Neighborhood Hits	310	Shared Neighborhood Hits	24
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NEBL_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.064380 (rank : 221)
Query Neighborhood Hits	176	Target Neighborhood Hits	457	Shared Neighborhood Hits	23
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.055357 (rank : 277)
Query Neighborhood Hits	176	Target Neighborhood Hits	420	Shared Neighborhood Hits	25
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NOXO1_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.072831 (rank : 196)
Query Neighborhood Hits	176	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

NOXO1_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.074473 (rank : 191)
Query Neighborhood Hits	176	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.063538 (rank : 225)
Query Neighborhood Hits	176	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.069482 (rank : 205)
Query Neighborhood Hits	176	Target Neighborhood Hits	267	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

OSTF1_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.067059 (rank : 212)
Query Neighborhood Hits	176	Target Neighborhood Hits	466	Shared Neighborhood Hits	18
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.066102 (rank : 216)
Query Neighborhood Hits	176	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

P85A_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.056009 (rank : 271)
Query Neighborhood Hits	176	Target Neighborhood Hits	479	Shared Neighborhood Hits	25
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.053601 (rank : 290)
Query Neighborhood Hits	176	Target Neighborhood Hits	435	Shared Neighborhood Hits	23
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.054634 (rank : 283)
Query Neighborhood Hits	176	Target Neighborhood Hits	543	Shared Neighborhood Hits	26
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.051517 (rank : 311)
Query Neighborhood Hits	176	Target Neighborhood Hits	519	Shared Neighborhood Hits	24
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PACN1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.058194 (rank : 251)
Query Neighborhood Hits	176	Target Neighborhood Hits	320	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.057990 (rank : 254)
Query Neighborhood Hits	176	Target Neighborhood Hits	283	Shared Neighborhood Hits	18
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.062569 (rank : 228)
Query Neighborhood Hits	176	Target Neighborhood Hits	339	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.062896 (rank : 227)
Query Neighborhood Hits	176	Target Neighborhood Hits	382	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.063758 (rank : 223)
Query Neighborhood Hits	176	Target Neighborhood Hits	385	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.063600 (rank : 224)
Query Neighborhood Hits	176	Target Neighborhood Hits	380	Shared Neighborhood Hits	22
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PDZD1_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.054991 (rank : 280)
Query Neighborhood Hits	176	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD3_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.055869 (rank : 272)
Query Neighborhood Hits	176	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD8_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.050230 (rank : 318)
Query Neighborhood Hits	176	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PEX13_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.056779 (rank : 262)
Query Neighborhood Hits	176	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.059162 (rank : 242)
Query Neighborhood Hits	176	Target Neighborhood Hits	126	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PKHF1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.119343 (rank : 88)
Query Neighborhood Hits	176	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.118855 (rank : 90)
Query Neighborhood Hits	176	Target Neighborhood Hits	80	Shared Neighborhood Hits	15
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF2_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.125339 (rank : 82)
Query Neighborhood Hits	176	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF2_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.124684 (rank : 84)
Query Neighborhood Hits	176	Target Neighborhood Hits	77	Shared Neighborhood Hits	15
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHG4_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.261485 (rank : 69)
Query Neighborhood Hits	176	Target Neighborhood Hits	200	Shared Neighborhood Hits	74
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

PLCG1_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.083315 (rank : 149)
Query Neighborhood Hits	176	Target Neighborhood Hits	293	Shared Neighborhood Hits	17
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.085671 (rank : 142)
Query Neighborhood Hits	176	Target Neighborhood Hits	314	Shared Neighborhood Hits	17
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.070929 (rank : 200)
Query Neighborhood Hits	176	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PPIP1_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.085862 (rank : 139)
Query Neighborhood Hits	176	Target Neighborhood Hits	389	Shared Neighborhood Hits	23
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

PPIP1_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.081985 (rank : 159)
Query Neighborhood Hits	176	Target Neighborhood Hits	377	Shared Neighborhood Hits	25
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

RBNS5_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.073436 (rank : 194)
Query Neighborhood Hits	176	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RBNS5_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.069705 (rank : 204)
Query Neighborhood Hits	176	Target Neighborhood Hits	266	Shared Neighborhood Hits	22
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

REPS1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.066384 (rank : 215)
Query Neighborhood Hits	176	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REPS1_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.068770 (rank : 207)
Query Neighborhood Hits	176	Target Neighborhood Hits	204	Shared Neighborhood Hits	15
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REPS2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.078810 (rank : 173)
Query Neighborhood Hits	176	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

REPS2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.077964 (rank : 176)
Query Neighborhood Hits	176	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

RGS3_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.053475 (rank : 291)
Query Neighborhood Hits	176	Target Neighborhood Hits	1621	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHG04_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.062437 (rank : 230)
Query Neighborhood Hits	176	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHPN1_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.061103 (rank : 233)
Query Neighborhood Hits	176	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.065293 (rank : 219)
Query Neighborhood Hits	176	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RIMB2_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.058041 (rank : 252)
Query Neighborhood Hits	176	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.058609 (rank : 246)
Query Neighborhood Hits	176	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RPTN_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.055370 (rank : 276)
Query Neighborhood Hits	176	Target Neighborhood Hits	650	Shared Neighborhood Hits	64
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RUFY1_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.052874 (rank : 295)
Query Neighborhood Hits	176	Target Neighborhood Hits	848	Shared Neighborhood Hits	28
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.052658 (rank : 298)
Query Neighborhood Hits	176	Target Neighborhood Hits	765	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.052876 (rank : 294)
Query Neighborhood Hits	176	Target Neighborhood Hits	1208	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.055180 (rank : 279)
Query Neighborhood Hits	176	Target Neighborhood Hits	820	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SCAR3_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.065495 (rank : 218)
Query Neighborhood Hits	176	Target Neighborhood Hits	239	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

SFTPD_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.058558 (rank : 247)
Query Neighborhood Hits	176	Target Neighborhood Hits	238	Shared Neighborhood Hits	55
SwissProt Accessions	P35247, Q86YK9, Q9UCJ2, Q9UCJ3	Gene names	SFTPD, PSPD, SFTP4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SFTPD_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.056058 (rank : 270)
Query Neighborhood Hits	176	Target Neighborhood Hits	217	Shared Neighborhood Hits	53
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SH3G1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.078493 (rank : 175)
Query Neighborhood Hits	176	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.076048 (rank : 182)
Query Neighborhood Hits	176	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.075527 (rank : 183)
Query Neighborhood Hits	176	Target Neighborhood Hits	324	Shared Neighborhood Hits	20
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G2_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.074028 (rank : 193)
Query Neighborhood Hits	176	Target Neighborhood Hits	319	Shared Neighborhood Hits	19
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G3_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.079954 (rank : 169)
Query Neighborhood Hits	176	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G3_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.081065 (rank : 166)
Query Neighborhood Hits	176	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SH3K1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.138348 (rank : 73)
Query Neighborhood Hits	176	Target Neighborhood Hits	341	Shared Neighborhood Hits	24
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.125594 (rank : 81)
Query Neighborhood Hits	176	Target Neighborhood Hits	332	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SHAN1_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.081828 (rank : 161)
Query Neighborhood Hits	176	Target Neighborhood Hits	1041	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHAN2_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.060079 (rank : 237)
Query Neighborhood Hits	176	Target Neighborhood Hits	346	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.110071 (rank : 95)
Query Neighborhood Hits	176	Target Neighborhood Hits	446	Shared Neighborhood Hits	30
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SOS1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.133236 (rank : 75)
Query Neighborhood Hits	176	Target Neighborhood Hits	274	Shared Neighborhood Hits	33
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.123681 (rank : 86)
Query Neighborhood Hits	176	Target Neighborhood Hits	281	Shared Neighborhood Hits	30
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS2_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.124222 (rank : 85)
Query Neighborhood Hits	176	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SRBS1_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.131431 (rank : 77)
Query Neighborhood Hits	176	Target Neighborhood Hits	409	Shared Neighborhood Hits	31
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRC8_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.087059 (rank : 131)
Query Neighborhood Hits	176	Target Neighborhood Hits	269	Shared Neighborhood Hits	19
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

SRC8_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.086605 (rank : 133)
Query Neighborhood Hits	176	Target Neighborhood Hits	292	Shared Neighborhood Hits	22
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRGP1_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.051131 (rank : 314)
Query Neighborhood Hits	176	Target Neighborhood Hits	390	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

STAC3_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.089687 (rank : 118)
Query Neighborhood Hits	176	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.090536 (rank : 113)
Query Neighborhood Hits	176	Target Neighborhood Hits	232	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.104872 (rank : 96)
Query Neighborhood Hits	176	Target Neighborhood Hits	276	Shared Neighborhood Hits	21
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.102426 (rank : 97)
Query Neighborhood Hits	176	Target Neighborhood Hits	268	Shared Neighborhood Hits	21
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAM1_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.092466 (rank : 105)
Query Neighborhood Hits	176	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.092785 (rank : 104)
Query Neighborhood Hits	176	Target Neighborhood Hits	273	Shared Neighborhood Hits	19
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.087026 (rank : 132)
Query Neighborhood Hits	176	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.087414 (rank : 128)
Query Neighborhood Hits	176	Target Neighborhood Hits	285	Shared Neighborhood Hits	20
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

TCGAP_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.062562 (rank : 229)
Query Neighborhood Hits	176	Target Neighborhood Hits	872	Shared Neighborhood Hits	70
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.067719 (rank : 210)
Query Neighborhood Hits	176	Target Neighborhood Hits	409	Shared Neighborhood Hits	48
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

UN13A_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.054293 (rank : 284)
Query Neighborhood Hits	176	Target Neighborhood Hits	285	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

VINEX_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.120479 (rank : 87)
Query Neighborhood Hits	176	Target Neighborhood Hits	270	Shared Neighborhood Hits	25
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.118973 (rank : 89)
Query Neighborhood Hits	176	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ZFY16_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.082165 (rank : 154)
Query Neighborhood Hits	176	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

ZFY16_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.084382 (rank : 146)
Query Neighborhood Hits	176	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZFY19_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.057161 (rank : 260)
Query Neighborhood Hits	176	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

ZFY19_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.053728 (rank : 289)
Query Neighborhood Hits	176	Target Neighborhood Hits	143	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

ZFY21_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.080210 (rank : 167)
Query Neighborhood Hits	176	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY21_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.082025 (rank : 158)
Query Neighborhood Hits	176	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

ZFY28_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.093487 (rank : 103)
Query Neighborhood Hits	176	Target Neighborhood Hits	152	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZFYV1_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.051941 (rank : 308)
Query Neighborhood Hits	176	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZFYV1_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.050877 (rank : 316)
Query Neighborhood Hits	176	Target Neighborhood Hits	153	Shared Neighborhood Hits	13
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

ZFYV9_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.088610 (rank : 120)
Query Neighborhood Hits	176	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

Hits sorted by NC score

ARHG1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	176	Target Neighborhood Hits	176	Shared Neighborhood Hits	176
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG1_MOUSE
NC score	0.969890 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	176	Target Neighborhood Hits	266	Shared Neighborhood Hits	119
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHGC_MOUSE
NC score	0.865124 (rank : 3)	θ value	8.33966e-147 (rank : 3)
Query Neighborhood Hits	176	Target Neighborhood Hits	344	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LBC_HUMAN
NC score	0.864964 (rank : 4)	θ value	8.87376e-48 (rank : 6)
Query Neighborhood Hits	176	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q12802	Gene names	LBC
Domain Architecture
Description	LBC oncogene (P47) (Lymphoid blast crisis oncogene).

ARHGC_HUMAN
NC score	0.860930 (rank : 5)	θ value	3.41741e-116 (rank : 4)
Query Neighborhood Hits	176	Target Neighborhood Hits	351	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGB_HUMAN
NC score	0.835875 (rank : 6)	θ value	5.14231e-88 (rank : 5)
Query Neighborhood Hits	176	Target Neighborhood Hits	375	Shared Neighborhood Hits	74
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHG2_MOUSE
NC score	0.831236 (rank : 7)	θ value	9.83387e-39 (rank : 7)
Query Neighborhood Hits	176	Target Neighborhood Hits	120	Shared Neighborhood Hits	57
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG2_HUMAN
NC score	0.819421 (rank : 8)	θ value	2.67802e-36 (rank : 8)
Query Neighborhood Hits	176	Target Neighborhood Hits	142	Shared Neighborhood Hits	59
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG3_MOUSE
NC score	0.720934 (rank : 9)	θ value	3.07829e-16 (rank : 14)
Query Neighborhood Hits	176	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG3_HUMAN
NC score	0.720295 (rank : 10)	θ value	1.16975e-15 (rank : 17)
Query Neighborhood Hits	176	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG8_HUMAN
NC score	0.705108 (rank : 11)	θ value	3.07829e-16 (rank : 15)
Query Neighborhood Hits	176	Target Neighborhood Hits	85	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

RGNEF_MOUSE
NC score	0.699731 (rank : 12)	θ value	1.52067e-31 (rank : 9)
Query Neighborhood Hits	176	Target Neighborhood Hits	641	Shared Neighborhood Hits	66
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

ARHGG_HUMAN
NC score	0.689688 (rank : 13)	θ value	5.43371e-13 (rank : 29)
Query Neighborhood Hits	176	Target Neighborhood Hits	129	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHG8_MOUSE
NC score	0.688636 (rank : 14)	θ value	5.25075e-16 (rank : 16)
Query Neighborhood Hits	176	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ECT2_MOUSE
NC score	0.683275 (rank : 15)	θ value	3.76295e-14 (rank : 20)
Query Neighborhood Hits	176	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ARHGG_MOUSE
NC score	0.678401 (rank : 16)	θ value	4.16044e-13 (rank : 27)
Query Neighborhood Hits	176	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARHG5_HUMAN
NC score	0.673127 (rank : 17)	θ value	9.26847e-13 (rank : 30)
Query Neighborhood Hits	176	Target Neighborhood Hits	172	Shared Neighborhood Hits	63
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ECT2_HUMAN
NC score	0.666632 (rank : 18)	θ value	4.16044e-13 (rank : 28)
Query Neighborhood Hits	176	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

NGEF_HUMAN
NC score	0.665052 (rank : 19)	θ value	6.41864e-14 (rank : 22)
Query Neighborhood Hits	176	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NGEF_MOUSE
NC score	0.651711 (rank : 20)	θ value	3.18553e-13 (rank : 24)
Query Neighborhood Hits	176	Target Neighborhood Hits	228	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

ARHGF_HUMAN
NC score	0.640509 (rank : 21)	θ value	6.64225e-11 (rank : 36)
Query Neighborhood Hits	176	Target Neighborhood Hits	214	Shared Neighborhood Hits	65
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

FGD3_MOUSE
NC score	0.590707 (rank : 22)	θ value	2.98157e-11 (rank : 32)
Query Neighborhood Hits	176	Target Neighborhood Hits	257	Shared Neighborhood Hits	70
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

PREX1_HUMAN
NC score	0.582169 (rank : 23)	θ value	6.87365e-08 (rank : 46)
Query Neighborhood Hits	176	Target Neighborhood Hits	177	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

TIAM1_MOUSE
NC score	0.575494 (rank : 24)	θ value	4.76016e-09 (rank : 40)
Query Neighborhood Hits	176	Target Neighborhood Hits	205	Shared Neighborhood Hits	63
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

FGD3_HUMAN
NC score	0.567839 (rank : 25)	θ value	1.47974e-10 (rank : 37)
Query Neighborhood Hits	176	Target Neighborhood Hits	249	Shared Neighborhood Hits	82
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

TIAM1_HUMAN
NC score	0.567295 (rank : 26)	θ value	7.34386e-10 (rank : 38)
Query Neighborhood Hits	176	Target Neighborhood Hits	225	Shared Neighborhood Hits	63
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

FGD4_HUMAN
NC score	0.566971 (rank : 27)	θ value	3.40345e-15 (rank : 18)
Query Neighborhood Hits	176	Target Neighborhood Hits	219	Shared Neighborhood Hits	63
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
NC score	0.565909 (rank : 28)	θ value	4.44505e-15 (rank : 19)
Query Neighborhood Hits	176	Target Neighborhood Hits	227	Shared Neighborhood Hits	64
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD2_MOUSE
NC score	0.558707 (rank : 29)	θ value	2.98157e-11 (rank : 31)
Query Neighborhood Hits	176	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD2_HUMAN
NC score	0.554124 (rank : 30)	θ value	5.08577e-11 (rank : 35)
Query Neighborhood Hits	176	Target Neighborhood Hits	151	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

ARHG4_MOUSE
NC score	0.549437 (rank : 31)	θ value	8.11959e-09 (rank : 41)
Query Neighborhood Hits	176	Target Neighborhood Hits	185	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG9_HUMAN
NC score	0.543824 (rank : 32)	θ value	5.26297e-08 (rank : 44)
Query Neighborhood Hits	176	Target Neighborhood Hits	235	Shared Neighborhood Hits	61
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

PKHG1_HUMAN
NC score	0.543788 (rank : 33)	θ value	8.97725e-08 (rank : 49)
Query Neighborhood Hits	176	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ARHG9_MOUSE
NC score	0.543209 (rank : 34)	θ value	5.26297e-08 (rank : 45)
Query Neighborhood Hits	176	Target Neighborhood Hits	234	Shared Neighborhood Hits	61
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

FGD1_MOUSE
NC score	0.539793 (rank : 35)	θ value	1.38499e-08 (rank : 43)
Query Neighborhood Hits	176	Target Neighborhood Hits	387	Shared Neighborhood Hits	91
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_HUMAN
NC score	0.534173 (rank : 36)	θ value	8.97725e-08 (rank : 48)
Query Neighborhood Hits	176	Target Neighborhood Hits	367	Shared Neighborhood Hits	87
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ARHG4_HUMAN
NC score	0.523695 (rank : 37)	θ value	8.97725e-08 (rank : 47)
Query Neighborhood Hits	176	Target Neighborhood Hits	242	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHGA_HUMAN
NC score	0.522562 (rank : 38)	θ value	2.79066e-09 (rank : 39)
Query Neighborhood Hits	176	Target Neighborhood Hits	187	Shared Neighborhood Hits	58
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

VAV_MOUSE
NC score	0.496450 (rank : 39)	θ value	3.76295e-14 (rank : 21)
Query Neighborhood Hits	176	Target Neighborhood Hits	430	Shared Neighborhood Hits	62
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VAV2_MOUSE
NC score	0.494129 (rank : 40)	θ value	3.89403e-11 (rank : 34)
Query Neighborhood Hits	176	Target Neighborhood Hits	456	Shared Neighborhood Hits	70
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ARHGA_MOUSE
NC score	0.493817 (rank : 41)	θ value	8.11959e-09 (rank : 42)
Query Neighborhood Hits	176	Target Neighborhood Hits	125	Shared Neighborhood Hits	57
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

VAV2_HUMAN
NC score	0.493639 (rank : 42)	θ value	3.89403e-11 (rank : 33)
Query Neighborhood Hits	176	Target Neighborhood Hits	453	Shared Neighborhood Hits	60
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ITSN2_HUMAN
NC score	0.487251 (rank : 43)	θ value	1.80048e-24 (rank : 10)
Query Neighborhood Hits	176	Target Neighborhood Hits	1173	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

VAV_HUMAN
NC score	0.479894 (rank : 44)	θ value	3.18553e-13 (rank : 26)
Query Neighborhood Hits	176	Target Neighborhood Hits	452	Shared Neighborhood Hits	61
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

MCF2_HUMAN
NC score	0.476256 (rank : 45)	θ value	0.000121331 (rank : 53)
Query Neighborhood Hits	176	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

VAV3_MOUSE
NC score	0.470769 (rank : 46)	θ value	2.43908e-13 (rank : 23)
Query Neighborhood Hits	176	Target Neighborhood Hits	404	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV3_HUMAN
NC score	0.469540 (rank : 47)	θ value	3.18553e-13 (rank : 25)
Query Neighborhood Hits	176	Target Neighborhood Hits	398	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

ITSN2_MOUSE
NC score	0.461273 (rank : 48)	θ value	2.59989e-23 (rank : 13)
Query Neighborhood Hits	176	Target Neighborhood Hits	1371	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

FGD6_HUMAN
NC score	0.456526 (rank : 49)	θ value	3.41135e-07 (rank : 50)
Query Neighborhood Hits	176	Target Neighborhood Hits	237	Shared Neighborhood Hits	61
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
NC score	0.456468 (rank : 50)	θ value	3.41135e-07 (rank : 51)
Query Neighborhood Hits	176	Target Neighborhood Hits	282	Shared Neighborhood Hits	60
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ITSN1_HUMAN
NC score	0.445117 (rank : 51)	θ value	2.35151e-24 (rank : 11)
Query Neighborhood Hits	176	Target Neighborhood Hits	1757	Shared Neighborhood Hits	84
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.444183 (rank : 52)	θ value	1.5242e-23 (rank : 12)
Query Neighborhood Hits	176	Target Neighborhood Hits	1669	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MCF2L_MOUSE
NC score	0.440452 (rank : 53)	θ value	0.00665767 (rank : 57)
Query Neighborhood Hits	176	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

DNMBP_MOUSE
NC score	0.426799 (rank : 54)	θ value	0.00035302 (rank : 54)
Query Neighborhood Hits	176	Target Neighborhood Hits	435	Shared Neighborhood Hits	66
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_HUMAN
NC score	0.419746 (rank : 55)	θ value	2.44474e-05 (rank : 52)
Query Neighborhood Hits	176	Target Neighborhood Hits	413	Shared Neighborhood Hits	67
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

HAPIP_HUMAN
NC score	0.348041 (rank : 56)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	176	Target Neighborhood Hits	350	Shared Neighborhood Hits	67
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

FGD5_HUMAN
NC score	0.337640 (rank : 57)	θ value	0.00102713 (rank : 55)
Query Neighborhood Hits	176	Target Neighborhood Hits	235	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

GNRP_MOUSE
NC score	0.326211 (rank : 58)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	176	Target Neighborhood Hits	191	Shared Neighborhood Hits	53
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

ARHG7_HUMAN
NC score	0.320794 (rank : 59)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	176	Target Neighborhood Hits	347	Shared Neighborhood Hits	61
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

FGD5_MOUSE
NC score	0.313089 (rank : 60)	θ value	0.0113563 (rank : 58)
Query Neighborhood Hits	176	Target Neighborhood Hits	170	Shared Neighborhood Hits	43
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FARP2_MOUSE
NC score	0.311448 (rank : 61)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	176	Target Neighborhood Hits	209	Shared Neighborhood Hits	60
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GNRP_HUMAN
NC score	0.305670 (rank : 62)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	176	Target Neighborhood Hits	239	Shared Neighborhood Hits	52
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

ARHG7_MOUSE
NC score	0.300346 (rank : 63)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	176	Target Neighborhood Hits	396	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

ARHG6_HUMAN
NC score	0.287165 (rank : 64)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	176	Target Neighborhood Hits	376	Shared Neighborhood Hits	52
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

FARP2_HUMAN
NC score	0.281058 (rank : 65)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	176	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP1_HUMAN
NC score	0.276813 (rank : 66)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	176	Target Neighborhood Hits	241	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

BCR_HUMAN
NC score	0.268685 (rank : 67)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	176	Target Neighborhood Hits	204	Shared Neighborhood Hits	55
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

ARHG6_MOUSE
NC score	0.266299 (rank : 68)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	176	Target Neighborhood Hits	394	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

PKHG4_HUMAN
NC score	0.261485 (rank : 69)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	176	Target Neighborhood Hits	200	Shared Neighborhood Hits	74
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

ABR_HUMAN
NC score	0.261058 (rank : 70)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	176	Target Neighborhood Hits	166	Shared Neighborhood Hits	56
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

DUET_HUMAN
NC score	0.158919 (rank : 71)	θ value	0.0431538 (rank : 62)
Query Neighborhood Hits	176	Target Neighborhood Hits	1220	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

TRIO_HUMAN
NC score	0.147053 (rank : 72)	θ value	0.163984 (rank : 68)
Query Neighborhood Hits	176	Target Neighborhood Hits	1580	Shared Neighborhood Hits	83
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

SH3K1_HUMAN
NC score	0.138348 (rank : 73)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	176	Target Neighborhood Hits	341	Shared Neighborhood Hits	24
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

NCF1_HUMAN
NC score	0.136089 (rank : 74)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	176	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

SOS1_HUMAN
NC score	0.133236 (rank : 75)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	176	Target Neighborhood Hits	274	Shared Neighborhood Hits	33
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

CD2AP_MOUSE
NC score	0.132541 (rank : 76)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	176	Target Neighborhood Hits	336	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

SRBS1_MOUSE
NC score	0.131431 (rank : 77)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	176	Target Neighborhood Hits	409	Shared Neighborhood Hits	31
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

NCF1_MOUSE
NC score	0.131266 (rank : 78)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	176	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

CD2AP_HUMAN
NC score	0.131221 (rank : 79)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	176	Target Neighborhood Hits	315	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

SRBS1_HUMAN
NC score	0.128512 (rank : 80)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	176	Target Neighborhood Hits	396	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SH3K1_MOUSE
NC score	0.125594 (rank : 81)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	176	Target Neighborhood Hits	332	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

PKHF2_HUMAN
NC score	0.125339 (rank : 82)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	176	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

NCF2_HUMAN
NC score	0.124689 (rank : 83)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	176	Target Neighborhood Hits	229	Shared Neighborhood Hits	22
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

PKHF2_MOUSE
NC score	0.124684 (rank : 84)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	176	Target Neighborhood Hits	77	Shared Neighborhood Hits	15
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

SOS2_HUMAN
NC score	0.124222 (rank : 85)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	176	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SOS1_MOUSE
NC score	0.123681 (rank : 86)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	176	Target Neighborhood Hits	281	Shared Neighborhood Hits	30
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

VINEX_HUMAN
NC score	0.120479 (rank : 87)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	176	Target Neighborhood Hits	270	Shared Neighborhood Hits	25
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

PKHF1_HUMAN
NC score	0.119343 (rank : 88)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	176	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

VINEX_MOUSE
NC score	0.118973 (rank : 89)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	176	Target Neighborhood Hits	286	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

PKHF1_MOUSE
NC score	0.118855 (rank : 90)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	176	Target Neighborhood Hits	80	Shared Neighborhood Hits	15
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

NCK1_HUMAN
NC score	0.116529 (rank : 91)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	176	Target Neighborhood Hits	312	Shared Neighborhood Hits	23
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

GRAP_HUMAN
NC score	0.115831 (rank : 92)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	176	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
NC score	0.114578 (rank : 93)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	176	Target Neighborhood Hits	309	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

NCK2_HUMAN
NC score	0.113095 (rank : 94)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	176	Target Neighborhood Hits	310	Shared Neighborhood Hits	24
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

SHAN2_MOUSE
NC score	0.110071 (rank : 95)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	176	Target Neighborhood Hits	446	Shared Neighborhood Hits	30
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

STAC_HUMAN
NC score	0.104872 (rank : 96)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	176	Target Neighborhood Hits	276	Shared Neighborhood Hits	21
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
NC score	0.102426 (rank : 97)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	176	Target Neighborhood Hits	268	Shared Neighborhood Hits	21
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

GRB2_HUMAN
NC score	0.101270 (rank : 98)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	176	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.101175 (rank : 99)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	176	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

NCF4_HUMAN
NC score	0.100712 (rank : 100)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	176	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
NC score	0.100378 (rank : 101)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	176	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

CO5A1_MOUSE
NC score	0.094909 (rank : 102)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	176	Target Neighborhood Hits	419	Shared Neighborhood Hits	64
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

ZFY28_HUMAN
NC score	0.093487 (rank : 103)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	176	Target Neighborhood Hits	152	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

STAM1_MOUSE
NC score	0.092785 (rank : 104)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	176	Target Neighborhood Hits	273	Shared Neighborhood Hits	19
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_HUMAN
NC score	0.092466 (rank : 105)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	176	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CO4A5_HUMAN
NC score	0.092463 (rank : 106)	θ value	0.0330416 (rank : 60)
Query Neighborhood Hits	176	Target Neighborhood Hits	383	Shared Neighborhood Hits	68
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO8A1_HUMAN
NC score	0.092314 (rank : 107)	θ value	0.0148317 (rank : 59)
Query Neighborhood Hits	176	Target Neighborhood Hits	288	Shared Neighborhood Hits	59
SwissProt Accessions	P27658, Q96D07	Gene names	COL8A1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor (Endothelial collagen).

CRKL_HUMAN
NC score	0.091988 (rank : 108)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	176	Target Neighborhood Hits	313	Shared Neighborhood Hits	18
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CO5A1_HUMAN
NC score	0.091936 (rank : 109)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	176	Target Neighborhood Hits	434	Shared Neighborhood Hits	65
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

ABI2_HUMAN
NC score	0.090831 (rank : 110)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	176	Target Neighborhood Hits	350	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CO8A1_MOUSE
NC score	0.090825 (rank : 111)	θ value	0.0330416 (rank : 61)
Query Neighborhood Hits	176	Target Neighborhood Hits	251	Shared Neighborhood Hits	58
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

HCLS1_MOUSE
NC score	0.090765 (rank : 112)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	176	Target Neighborhood Hits	329	Shared Neighborhood Hits	26
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

STAC3_MOUSE
NC score	0.090536 (rank : 113)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	176	Target Neighborhood Hits	232	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

HCLS1_HUMAN
NC score	0.090065 (rank : 114)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	176	Target Neighborhood Hits	358	Shared Neighborhood Hits	28
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ABI2_MOUSE
NC score	0.089851 (rank : 115)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	176	Target Neighborhood Hits	266	Shared Neighborhood Hits	23
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

CO8A2_HUMAN
NC score	0.089797 (rank : 116)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	176	Target Neighborhood Hits	299	Shared Neighborhood Hits	65
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CONA1_MOUSE
NC score	0.089737 (rank : 117)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	176	Target Neighborhood Hits	254	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

STAC3_HUMAN
NC score	0.089687 (rank : 118)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	176	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CRKL_MOUSE
NC score	0.089297 (rank : 119)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	176	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

ZFYV9_HUMAN
NC score	0.088610 (rank : 120)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	176	Target Neighborhood Hits	134	Shared Neighborhood Hits	14
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

GRAP2_HUMAN
NC score	0.088367 (rank : 121)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	176	Target Neighborhood Hits	304	Shared Neighborhood Hits	18
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

CO4A2_HUMAN
NC score	0.088213 (rank : 122)	θ value	0.813845 (rank : 82)
Query Neighborhood Hits	176	Target Neighborhood Hits	454	Shared Neighborhood Hits	64
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COBA1_HUMAN
NC score	0.088179 (rank : 123)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	176	Target Neighborhood Hits	491	Shared Neighborhood Hits	67
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
NC score	0.088035 (rank : 124)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	176	Target Neighborhood Hits	487	Shared Neighborhood Hits	68
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

GRAP2_MOUSE
NC score	0.087989 (rank : 125)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	176	Target Neighborhood Hits	297	Shared Neighborhood Hits	18
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

CO6A2_MOUSE
NC score	0.087793 (rank : 126)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	176	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

BI2L1_HUMAN
NC score	0.087659 (rank : 127)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	176	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

STAM2_MOUSE
NC score	0.087414 (rank : 128)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	176	Target Neighborhood Hits	285	Shared Neighborhood Hits	20
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

COBA2_HUMAN
NC score	0.087138 (rank : 129)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	176	Target Neighborhood Hits	408	Shared Neighborhood Hits	63
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

ABI1_MOUSE
NC score	0.087067 (rank : 130)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	176	Target Neighborhood Hits	246	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

SRC8_HUMAN
NC score	0.087059 (rank : 131)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	176	Target Neighborhood Hits	269	Shared Neighborhood Hits	19
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

STAM2_HUMAN
NC score	0.087026 (rank : 132)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	176	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

SRC8_MOUSE
NC score	0.086605 (rank : 133)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	176	Target Neighborhood Hits	292	Shared Neighborhood Hits	22
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

CO6A2_HUMAN
NC score	0.086367 (rank : 134)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	176	Target Neighborhood Hits	249	Shared Neighborhood Hits	62
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CO5A3_HUMAN
NC score	0.086334 (rank : 135)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	176	Target Neighborhood Hits	433	Shared Neighborhood Hits	64
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO1A1_HUMAN
NC score	0.086067 (rank : 136)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	176	Target Neighborhood Hits	475	Shared Neighborhood Hits	65
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO4A2_MOUSE
NC score	0.086023 (rank : 137)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	176	Target Neighborhood Hits	492	Shared Neighborhood Hits	65
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO3A1_MOUSE
NC score	0.085969 (rank : 138)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	176	Target Neighborhood Hits	466	Shared Neighborhood Hits	65
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

PPIP1_HUMAN
NC score	0.085862 (rank : 139)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	176	Target Neighborhood Hits	389	Shared Neighborhood Hits	23
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

CO3A1_HUMAN
NC score	0.085739 (rank : 140)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	176	Target Neighborhood Hits	452	Shared Neighborhood Hits	67
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COBA2_MOUSE
NC score	0.085707 (rank : 141)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	176	Target Neighborhood Hits	501	Shared Neighborhood Hits	64
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

PLCG1_MOUSE
NC score	0.085671 (rank : 142)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	176	Target Neighborhood Hits	314	Shared Neighborhood Hits	17
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

CO1A1_MOUSE
NC score	0.085445 (rank : 143)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	176	Target Neighborhood Hits	457	Shared Neighborhood Hits	67
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CONA1_HUMAN
NC score	0.084504 (rank : 144)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	176	Target Neighborhood Hits	281	Shared Neighborhood Hits	63
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CO2A1_HUMAN
NC score	0.084478 (rank : 145)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	176	Target Neighborhood Hits	486	Shared Neighborhood Hits	69
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

ZFY16_MOUSE
NC score	0.084382 (rank : 146)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	176	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

CO4A1_MOUSE
NC score	0.084009 (rank : 147)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	176	Target Neighborhood Hits	450	Shared Neighborhood Hits	65
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A6_HUMAN
NC score	0.083650 (rank : 148)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	176	Target Neighborhood Hits	318	Shared Neighborhood Hits	60
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

PLCG1_HUMAN
NC score	0.083315 (rank : 149)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	176	Target Neighborhood Hits	293	Shared Neighborhood Hits	17
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

CO8A2_MOUSE
NC score	0.083243 (rank : 150)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	176	Target Neighborhood Hits	273	Shared Neighborhood Hits	59
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

CO4A1_HUMAN
NC score	0.083225 (rank : 151)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	176	Target Neighborhood Hits	425	Shared Neighborhood Hits	65
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO9A2_MOUSE
NC score	0.082262 (rank : 152)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	176	Target Neighborhood Hits	279	Shared Neighborhood Hits	61
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COGA1_HUMAN
NC score	0.082250 (rank : 153)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	176	Target Neighborhood Hits	345	Shared Neighborhood Hits	62
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

ZFY16_HUMAN
NC score	0.082165 (rank : 154)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	176	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

CO5A2_HUMAN
NC score	0.082147 (rank : 155)	θ value	0.0736092 (rank : 63)
Query Neighborhood Hits	176	Target Neighborhood Hits	760	Shared Neighborhood Hits	65
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CRK_MOUSE
NC score	0.082147 (rank : 156)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	176	Target Neighborhood Hits	314	Shared Neighborhood Hits	19
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

OGFR_MOUSE
NC score	0.082066 (rank : 157)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	176	Target Neighborhood Hits	584	Shared Neighborhood Hits	70
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

ZFY21_MOUSE
NC score	0.082025 (rank : 158)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	176	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VCM3, Q9D1E2	Gene names	Zfyve21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

PPIP1_MOUSE
NC score	0.081985 (rank : 159)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	176	Target Neighborhood Hits	377	Shared Neighborhood Hits	25
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

ABI1_HUMAN
NC score	0.081925 (rank : 160)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	176	Target Neighborhood Hits	257	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

SHAN1_HUMAN
NC score	0.081828 (rank : 161)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	176	Target Neighborhood Hits	1041	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

CO1A2_HUMAN
NC score	0.081822 (rank : 162)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	176	Target Neighborhood Hits	329	Shared Neighborhood Hits	60
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO2A1_MOUSE
NC score	0.081500 (rank : 163)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	176	Target Neighborhood Hits	483	Shared Neighborhood Hits	65
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

COJA1_HUMAN
NC score	0.081397 (rank : 164)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	176	Target Neighborhood Hits	323	Shared Neighborhood Hits	60
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CO4A3_HUMAN
NC score	0.081378 (rank : 165)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	176	Target Neighborhood Hits	421	Shared Neighborhood Hits	65
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

SH3G3_MOUSE
NC score	0.081065 (rank : 166)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	176	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

ZFY21_HUMAN
NC score	0.080210 (rank : 167)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	176	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BQ24, Q86T05, Q96LT1	Gene names	ZFYVE21
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 21.

CO1A2_MOUSE
NC score	0.080044 (rank : 168)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	176	Target Neighborhood Hits	388	Shared Neighborhood Hits	62
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

SH3G3_HUMAN
NC score	0.079954 (rank : 169)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	176	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

CRK_HUMAN
NC score	0.079832 (rank : 170)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	176	Target Neighborhood Hits	308	Shared Neighborhood Hits	18
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CO9A1_MOUSE
NC score	0.079545 (rank : 171)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	176	Target Neighborhood Hits	477	Shared Neighborhood Hits	61
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO4A4_HUMAN
NC score	0.079269 (rank : 172)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	176	Target Neighborhood Hits	440	Shared Neighborhood Hits	67
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

REPS2_HUMAN
NC score	0.078810 (rank : 173)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	176	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

CO9A3_HUMAN
NC score	0.078663 (rank : 174)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	176	Target Neighborhood Hits	361	Shared Neighborhood Hits	60
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

SH3G1_HUMAN
NC score	0.078493 (rank : 175)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	176	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

REPS2_MOUSE
NC score	0.077964 (rank : 176)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	176	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

CO9A2_HUMAN
NC score	0.077851 (rank : 177)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	176	Target Neighborhood Hits	261	Shared Neighborhood Hits	58
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COAA1_HUMAN
NC score	0.077450 (rank : 178)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	176	Target Neighborhood Hits	316	Shared Neighborhood Hits	62
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CO9A1_HUMAN
NC score	0.076383 (rank : 179)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	176	Target Neighborhood Hits	420	Shared Neighborhood Hits	60
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO6A1_HUMAN
NC score	0.076226 (rank : 180)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	176	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

ABI3_HUMAN
NC score	0.076208 (rank : 181)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	176	Target Neighborhood Hits	227	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

SH3G1_MOUSE
NC score	0.076048 (rank : 182)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	176	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_HUMAN
NC score	0.075527 (rank : 183)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	176	Target Neighborhood Hits	324	Shared Neighborhood Hits	20
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

COHA1_HUMAN
NC score	0.075252 (rank : 184)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	176	Target Neighborhood Hits	400	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COHA1_MOUSE
NC score	0.075210 (rank : 185)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	176	Target Neighborhood Hits	414	Shared Neighborhood Hits	64
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CO6A1_MOUSE
NC score	0.074955 (rank : 186)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	176	Target Neighborhood Hits	241	Shared Neighborhood Hits	58
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

HGS_MOUSE
NC score	0.074793 (rank : 187)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	176	Target Neighborhood Hits	589	Shared Neighborhood Hits	29
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
NC score	0.074764 (rank : 188)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	176	Target Neighborhood Hits	517	Shared Neighborhood Hits	25
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

ABI3_MOUSE
NC score	0.074754 (rank : 189)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	176	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AHI1_HUMAN
NC score	0.074611 (rank : 190)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	176	Target Neighborhood Hits	537	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

NOXO1_MOUSE
NC score	0.074473 (rank : 191)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	176	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

DBNL_HUMAN
NC score	0.074215 (rank : 192)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	176	Target Neighborhood Hits	244	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

SH3G2_MOUSE
NC score	0.074028 (rank : 193)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	176	Target Neighborhood Hits	319	Shared Neighborhood Hits	19
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

RBNS5_HUMAN
NC score	0.073436 (rank : 194)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	176	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

AHI1_MOUSE
NC score	0.073231 (rank : 195)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	176	Target Neighborhood Hits	496	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

NOXO1_HUMAN
NC score	0.072831 (rank : 196)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	176	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

COAA1_MOUSE
NC score	0.072752 (rank : 197)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	176	Target Neighborhood Hits	286	Shared Neighborhood Hits	58
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

BI2L1_MOUSE
NC score	0.072398 (rank : 198)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	176	Target Neighborhood Hits	197	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

MARCO_MOUSE
NC score	0.071501 (rank : 199)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	176	Target Neighborhood Hits	242	Shared Neighborhood Hits	57
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

PLCG2_HUMAN
NC score	0.070929 (rank : 200)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	176	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

LASP1_HUMAN
NC score	0.070700 (rank : 201)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	176	Target Neighborhood Hits	293	Shared Neighborhood Hits	20
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

CO7A1_HUMAN
NC score	0.070140 (rank : 202)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	176	Target Neighborhood Hits	807	Shared Neighborhood Hits	65
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DBNL_MOUSE
NC score	0.069988 (rank : 203)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	176	Target Neighborhood Hits	306	Shared Neighborhood Hits	24
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

RBNS5_MOUSE
NC score	0.069705 (rank : 204)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	176	Target Neighborhood Hits	266	Shared Neighborhood Hits	22
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

NPHP1_MOUSE
NC score	0.069482 (rank : 205)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	176	Target Neighborhood Hits	267	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

COLQ_HUMAN
NC score	0.069117 (rank : 206)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	176	Target Neighborhood Hits	193	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

REPS1_MOUSE
NC score	0.068770 (rank : 207)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	176	Target Neighborhood Hits	204	Shared Neighborhood Hits	15
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SCAR3_HUMAN
NC score	0.068675 (rank : 208)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	176	Target Neighborhood Hits	205	Shared Neighborhood Hits	56
SwissProt Accessions	Q6AZY7, Q9UM15, Q9UM16	Gene names	SCARA3, CSR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3 (Cellular stress response gene protein).

LASP1_MOUSE
NC score	0.068402 (rank : 209)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	176	Target Neighborhood Hits	297	Shared Neighborhood Hits	20
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

TCGAP_MOUSE
NC score	0.067719 (rank : 210)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	176	Target Neighborhood Hits	409	Shared Neighborhood Hits	48
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

COIA1_MOUSE
NC score	0.067100 (rank : 211)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	176	Target Neighborhood Hits	481	Shared Neighborhood Hits	67
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

OSTF1_HUMAN
NC score	0.067059 (rank : 212)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	176	Target Neighborhood Hits	466	Shared Neighborhood Hits	18
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

EMID1_MOUSE
NC score	0.066909 (rank : 213)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	176	Target Neighborhood Hits	230	Shared Neighborhood Hits	59
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

COIA1_HUMAN
NC score	0.066796 (rank : 214)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	176	Target Neighborhood Hits	447	Shared Neighborhood Hits	65
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

REPS1_HUMAN
NC score	0.066384 (rank : 215)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	176	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

OSTF1_MOUSE
NC score	0.066102 (rank : 216)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	176	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

BAIP2_MOUSE
NC score	0.065942 (rank : 217)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	176	Target Neighborhood Hits	185	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

SCAR3_MOUSE
NC score	0.065495 (rank : 218)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	176	Target Neighborhood Hits	239	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

RHPN1_MOUSE
NC score	0.065293 (rank : 219)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	176	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

BAIP2_HUMAN
NC score	0.065016 (rank : 220)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	176	Target Neighborhood Hits	192	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

NEBL_HUMAN
NC score	0.064380 (rank : 221)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	176	Target Neighborhood Hits	457	Shared Neighborhood Hits	23
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

ANM2_HUMAN
NC score	0.064295 (rank : 222)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	176	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

PACN3_HUMAN
NC score	0.063758 (rank : 223)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	176	Target Neighborhood Hits	385	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PACN3_MOUSE
NC score	0.063600 (rank : 224)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	176	Target Neighborhood Hits	380	Shared Neighborhood Hits	22
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

NPHP1_HUMAN
NC score	0.063538 (rank : 225)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	176	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

MARCO_HUMAN
NC score	0.063490 (rank : 226)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	176	Target Neighborhood Hits	199	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

PACN2_MOUSE
NC score	0.062896 (rank : 227)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	176	Target Neighborhood Hits	382	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_HUMAN
NC score	0.062569 (rank : 228)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	176	Target Neighborhood Hits	339	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

TCGAP_HUMAN
NC score	0.062562 (rank : 229)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	176	Target Neighborhood Hits	872	Shared Neighborhood Hits	70
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG04_HUMAN
NC score	0.062437 (rank : 230)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	176	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

C1QA_MOUSE
NC score	0.062276 (rank : 231)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	176	Target Neighborhood Hits	116	Shared Neighborhood Hits	49
SwissProt Accessions	P98086	Gene names	C1qa
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

IASPP_MOUSE
NC score	0.061957 (rank : 232)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	176	Target Neighborhood Hits	1024	Shared Neighborhood Hits	73
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

RHPN1_HUMAN
NC score	0.061103 (rank : 233)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	176	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

CASL_HUMAN
NC score	0.060944 (rank : 234)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	176	Target Neighborhood Hits	259	Shared Neighborhood Hits	28
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

BCAR1_MOUSE
NC score	0.060694 (rank : 235)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	176	Target Neighborhood Hits	438	Shared Neighborhood Hits	26
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

ANM2_MOUSE
NC score	0.060635 (rank : 236)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	176	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

SHAN2_HUMAN
NC score	0.060079 (rank : 237)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	176	Target Neighborhood Hits	346	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

COFA1_MOUSE
NC score	0.059889 (rank : 238)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	176	Target Neighborhood Hits	305	Shared Neighborhood Hits	60
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

C1QT7_MOUSE
NC score	0.059462 (rank : 239)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	176	Target Neighborhood Hits	124	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BVD7, Q8CHX9	Gene names	C1qtnf7, Ctrp7
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

C1QT2_HUMAN
NC score	0.059429 (rank : 240)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	176	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BXJ5	Gene names	C1QTNF2, CTRP2
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 2 precursor.

EFS_MOUSE
NC score	0.059255 (rank : 241)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	176	Target Neighborhood Hits	389	Shared Neighborhood Hits	26
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

PEX13_MOUSE
NC score	0.059162 (rank : 242)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	176	Target Neighborhood Hits	126	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

CT032_HUMAN
NC score	0.059094 (rank : 243)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	176	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

ADIPO_MOUSE
NC score	0.058852 (rank : 244)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	176	Target Neighborhood Hits	182	Shared Neighborhood Hits	52
SwissProt Accessions	Q60994, Q62400, Q9DC68	Gene names	Adipoq, Acdc, Acrp30, Apm1
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte-specific protein AdipoQ).

BCAR1_HUMAN
NC score	0.058723 (rank : 245)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	176	Target Neighborhood Hits	554	Shared Neighborhood Hits	32
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

RIMB2_MOUSE
NC score	0.058609 (rank : 246)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	176	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SFTPD_HUMAN
NC score	0.058558 (rank : 247)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	176	Target Neighborhood Hits	238	Shared Neighborhood Hits	55
SwissProt Accessions	P35247, Q86YK9, Q9UCJ2, Q9UCJ3	Gene names	SFTPD, PSPD, SFTP4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

EMID1_HUMAN
NC score	0.058401 (rank : 248)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	176	Target Neighborhood Hits	215	Shared Neighborhood Hits	56
SwissProt Accessions	Q96A84, Q6ICG1, Q86SS7	Gene names	EMID1, EMU1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

C1QB_MOUSE
NC score	0.058357 (rank : 249)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	176	Target Neighborhood Hits	126	Shared Neighborhood Hits	51
SwissProt Accessions	P14106	Gene names	C1qb
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

LMO7_HUMAN
NC score	0.058329 (rank : 250)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	176	Target Neighborhood Hits	507	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PACN1_HUMAN
NC score	0.058194 (rank : 251)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	176	Target Neighborhood Hits	320	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

RIMB2_HUMAN
NC score	0.058041 (rank : 252)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	176	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

C1QT7_HUMAN
NC score	0.058034 (rank : 253)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	176	Target Neighborhood Hits	119	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BXJ2	Gene names	C1QTNF7, CTRP7
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

PACN1_MOUSE
NC score	0.057990 (rank : 254)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	176	Target Neighborhood Hits	283	Shared Neighborhood Hits	18
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

C1QT5_HUMAN
NC score	0.057795 (rank : 255)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	176	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXJ0, Q8N6P2, Q9UFX4	Gene names	C1QTNF5, CTRP5
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

COFA1_HUMAN
NC score	0.057770 (rank : 256)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	176	Target Neighborhood Hits	292	Shared Neighborhood Hits	58
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

OGFR_HUMAN
NC score	0.057692 (rank : 257)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	176	Target Neighborhood Hits	1582	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

C1QA_HUMAN
NC score	0.057454 (rank : 258)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	176	Target Neighborhood Hits	179	Shared Neighborhood Hits	51
SwissProt Accessions	P02745, Q5T963	Gene names	C1QA
Domain Architecture
Description	Complement C1q subcomponent subunit A precursor.

C1QB_HUMAN
NC score	0.057260 (rank : 259)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	176	Target Neighborhood Hits	126	Shared Neighborhood Hits	49
SwissProt Accessions	P02746, Q5T959, Q96H17	Gene names	C1QB
Domain Architecture
Description	Complement C1q subcomponent subunit B precursor.

ZFY19_HUMAN
NC score	0.057161 (rank : 260)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	176	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

C1QC_MOUSE
NC score	0.057023 (rank : 261)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	176	Target Neighborhood Hits	150	Shared Neighborhood Hits	52
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

PEX13_HUMAN
NC score	0.056779 (rank : 262)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	176	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

EMID2_HUMAN
NC score	0.056776 (rank : 263)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	176	Target Neighborhood Hits	226	Shared Neighborhood Hits	54
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

ADIPO_HUMAN
NC score	0.056702 (rank : 264)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	176	Target Neighborhood Hits	169	Shared Neighborhood Hits	52
SwissProt Accessions	Q15848	Gene names	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Domain Architecture
Description	Adiponectin precursor (Adipocyte, C1q and collagen domain-containing protein) (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipose most abundant gene transcript 1) (apM-1) (Gelatin-binding protein).

C1QC_HUMAN
NC score	0.056517 (rank : 265)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	176	Target Neighborhood Hits	124	Shared Neighborhood Hits	48
SwissProt Accessions	P02747, Q7Z502, Q96DL2, Q96H05	Gene names	C1QC, C1QG
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

EFS_HUMAN
NC score	0.056117 (rank : 266)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	176	Target Neighborhood Hits	348	Shared Neighborhood Hits	23
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EP15R_MOUSE
NC score	0.056104 (rank : 267)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	176	Target Neighborhood Hits	1135	Shared Neighborhood Hits	28
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

COEA1_HUMAN
NC score	0.056093 (rank : 268)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	176	Target Neighborhood Hits	427	Shared Neighborhood Hits	62
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

MLL2_HUMAN
NC score	0.056077 (rank : 269)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	176	Target Neighborhood Hits	1788	Shared Neighborhood Hits	92
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SFTPD_MOUSE
NC score	0.056058 (rank : 270)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	176	Target Neighborhood Hits	217	Shared Neighborhood Hits	53
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

P85A_HUMAN
NC score	0.056009 (rank : 271)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	176	Target Neighborhood Hits	479	Shared Neighborhood Hits	25
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PDZD3_HUMAN
NC score	0.055869 (rank : 272)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	176	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

GLDN_MOUSE
NC score	0.055854 (rank : 273)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	176	Target Neighborhood Hits	155	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BMF8, Q80ZC5	Gene names	Gldn, Crgl2
Domain Architecture	No domain graphic available
Description	Gliomedin (Cancer-related gene liver 2 protein) (CRG-L2).

GLDN_HUMAN
NC score	0.055778 (rank : 274)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	176	Target Neighborhood Hits	159	Shared Neighborhood Hits	55
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

CASL_MOUSE
NC score	0.055492 (rank : 275)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	176	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

RPTN_MOUSE
NC score	0.055370 (rank : 276)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	176	Target Neighborhood Hits	650	Shared Neighborhood Hits	64
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

NEBU_HUMAN
NC score	0.055357 (rank : 277)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	176	Target Neighborhood Hits	420	Shared Neighborhood Hits	25
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

C1QT5_MOUSE
NC score	0.055241 (rank : 278)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	176	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K479	Gene names	C1qtnf5, Ctrp5
Domain Architecture	No domain graphic available
Description	Complement C1q tumor necrosis factor-related protein 5 precursor.

RUFY2_MOUSE
NC score	0.055180 (rank : 279)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	176	Target Neighborhood Hits	820	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

PDZD1_MOUSE
NC score	0.054991 (rank : 280)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	176	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ELN_MOUSE
NC score	0.054978 (rank : 281)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	176	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	P54320	Gene names	Eln
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

RGS3_HUMAN
NC score	0.054746 (rank : 282)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	176	Target Neighborhood Hits	1375	Shared Neighborhood Hits	85
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

P85B_HUMAN
NC score	0.054634 (rank : 283)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	176	Target Neighborhood Hits	543	Shared Neighborhood Hits	26
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

UN13A_HUMAN
NC score	0.054293 (rank : 284)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	176	Target Neighborhood Hits	285	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

MIA_MOUSE
NC score	0.054211 (rank : 285)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	176	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q61865, O09086, P97495	Gene names	Mia, Cdrap, Mia1
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity) (Cartilage-derived retinoic acid-sensitive protein) (CD-RAP).

MIA_HUMAN
NC score	0.054080 (rank : 286)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	176	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q16674	Gene names	MIA
Domain Architecture
Description	Melanoma-derived growth regulatory protein precursor (Melanoma inhibitory activity).

EDA_HUMAN
NC score	0.053930 (rank : 287)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	176	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

CO6A3_HUMAN
NC score	0.053885 (rank : 288)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	176	Target Neighborhood Hits	317	Shared Neighborhood Hits	58
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

ZFY19_MOUSE
NC score	0.053728 (rank : 289)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	176	Target Neighborhood Hits	143	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DAZ9, Q8VCV7	Gene names	Zfyve19
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19.

P85A_MOUSE
NC score	0.053601 (rank : 290)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	176	Target Neighborhood Hits	435	Shared Neighborhood Hits	23
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

RGS3_MOUSE
NC score	0.053475 (rank : 291)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	176	Target Neighborhood Hits	1621	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

EDA_MOUSE
NC score	0.053367 (rank : 292)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	176	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

N4BP2_HUMAN
NC score	0.053191 (rank : 293)	θ value	0.163984 (rank : 67)
Query Neighborhood Hits	176	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

RUFY2_HUMAN
NC score	0.052876 (rank : 294)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	176	Target Neighborhood Hits	1208	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY1_HUMAN
NC score	0.052874 (rank : 295)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	176	Target Neighborhood Hits	848	Shared Neighborhood Hits	28
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

EHD1_HUMAN
NC score	0.052779 (rank : 296)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	176	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H4M9, O14611, Q9UNR3	Gene names	EHD1, PAST, PAST1
Domain Architecture
Description	EH-domain-containing protein 1 (Testilin) (hPAST1).

EHD1_MOUSE
NC score	0.052691 (rank : 297)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	176	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVK4	Gene names	Ehd1, Past1
Domain Architecture
Description	EH-domain-containing protein 1 (mPAST1).

RUFY1_MOUSE
NC score	0.052658 (rank : 298)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	176	Target Neighborhood Hits	765	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

IASPP_HUMAN
NC score	0.052588 (rank : 299)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	176	Target Neighborhood Hits	688	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

SFTPA_MOUSE
NC score	0.052520 (rank : 300)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	176	Target Neighborhood Hits	169	Shared Neighborhood Hits	47
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

EP15_MOUSE
NC score	0.052339 (rank : 301)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	176	Target Neighborhood Hits	820	Shared Neighborhood Hits	18
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CTHR1_HUMAN
NC score	0.052327 (rank : 302)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	176	Target Neighborhood Hits	126	Shared Neighborhood Hits	50
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

EP15_HUMAN
NC score	0.052253 (rank : 303)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	176	Target Neighborhood Hits	1021	Shared Neighborhood Hits	26
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CTHR1_MOUSE
NC score	0.052240 (rank : 304)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	176	Target Neighborhood Hits	123	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

EMID2_MOUSE
NC score	0.052186 (rank : 305)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	176	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EHD2_HUMAN
NC score	0.052171 (rank : 306)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	176	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN4, Q96CB6	Gene names	EHD2
Domain Architecture
Description	EH-domain-containing protein 2.

EHD3_HUMAN
NC score	0.052075 (rank : 307)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	176	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZN3, Q8N514, Q9NZB3	Gene names	EHD3, EHD2
Domain Architecture
Description	EH-domain-containing protein 3.

ZFYV1_HUMAN
NC score	0.051941 (rank : 308)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	176	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

EP15R_HUMAN
NC score	0.051810 (rank : 309)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	176	Target Neighborhood Hits	1083	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EHD3_MOUSE
NC score	0.051699 (rank : 310)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	176	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXY6	Gene names	Ehd3, Ehd2
Domain Architecture
Description	EH-domain-containing protein 3.

P85B_MOUSE
NC score	0.051517 (rank : 311)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	176	Target Neighborhood Hits	519	Shared Neighborhood Hits	24
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

MSRE_HUMAN
NC score	0.051482 (rank : 312)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	176	Target Neighborhood Hits	298	Shared Neighborhood Hits	57
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

EHD4_MOUSE
NC score	0.051482 (rank : 313)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	176	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQP2	Gene names	Ehd4, Past2
Domain Architecture
Description	EH-domain-containing protein 4 (mPAST2).

SRGP1_HUMAN
NC score	0.051131 (rank : 314)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	176	Target Neighborhood Hits	390	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

COEA1_MOUSE
NC score	0.051121 (rank : 315)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	176	Target Neighborhood Hits	402	Shared Neighborhood Hits	60
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

ZFYV1_MOUSE
NC score	0.050877 (rank : 316)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	176	Target Neighborhood Hits	153	Shared Neighborhood Hits	13
SwissProt Accessions	Q810J8	Gene names	Zfyve1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1.

FYV1_HUMAN
NC score	0.050518 (rank : 317)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	176	Target Neighborhood Hits	217	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

PDZD8_HUMAN
NC score	0.050230 (rank : 318)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	176	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

HRX_HUMAN
NC score	0.047362 (rank : 319)	θ value	0.00102713 (rank : 56)
Query Neighborhood Hits	176	Target Neighborhood Hits	825	Shared Neighborhood Hits	37
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

GOPC_HUMAN
NC score	0.043612 (rank : 320)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	176	Target Neighborhood Hits	377	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

CGRE1_HUMAN
NC score	0.042680 (rank : 321)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	176	Target Neighborhood Hits	354	Shared Neighborhood Hits	56
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

SRRM2_MOUSE
NC score	0.042590 (rank : 322)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	176	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CP250_HUMAN
NC score	0.042040 (rank : 323)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	176	Target Neighborhood Hits	1805	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP250_MOUSE
NC score	0.039986 (rank : 324)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	176	Target Neighborhood Hits	1583	Shared Neighborhood Hits	35
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MED12_HUMAN
NC score	0.038665 (rank : 325)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	176	Target Neighborhood Hits	262	Shared Neighborhood Hits	11
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

RFIP3_HUMAN
NC score	0.038426 (rank : 326)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	176	Target Neighborhood Hits	1055	Shared Neighborhood Hits	43
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

MTSS1_MOUSE
NC score	0.036180 (rank : 327)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	176	Target Neighborhood Hits	592	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

BSN_MOUSE
NC score	0.036098 (rank : 328)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	176	Target Neighborhood Hits	2057	Shared Neighborhood Hits	86
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MINT_MOUSE
NC score	0.032770 (rank : 329)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	176	Target Neighborhood Hits	1514	Shared Neighborhood Hits	52
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CT151_HUMAN
NC score	0.032332 (rank : 330)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	176	Target Neighborhood Hits	382	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

SET1A_HUMAN
NC score	0.031999 (rank : 331)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	176	Target Neighborhood Hits	690	Shared Neighborhood Hits	25
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

RB6I2_MOUSE
NC score	0.031914 (rank : 332)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	176	Target Neighborhood Hits	1433	Shared Neighborhood Hits	29
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RB6I2_HUMAN
NC score	0.030222 (rank : 333)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	176	Target Neighborhood Hits	1584	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SYNE2_HUMAN
NC score	0.029865 (rank : 334)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	176	Target Neighborhood Hits	1323	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CEP55_MOUSE
NC score	0.029360 (rank : 335)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	176	Target Neighborhood Hits	693	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CI039_HUMAN
NC score	0.027334 (rank : 336)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	176	Target Neighborhood Hits	1171	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

TXND2_HUMAN
NC score	0.025635 (rank : 337)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	176	Target Neighborhood Hits	793	Shared Neighborhood Hits	28
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TGON2_HUMAN
NC score	0.022926 (rank : 338)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	176	Target Neighborhood Hits	1037	Shared Neighborhood Hits	46
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

BPA1_MOUSE
NC score	0.022890 (rank : 339)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	176	Target Neighborhood Hits	1477	Shared Neighborhood Hits	34
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GNAS3_HUMAN
NC score	0.021969 (rank : 340)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	176	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

NCOA5_HUMAN
NC score	0.020845 (rank : 341)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	176	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

MELPH_HUMAN
NC score	0.020782 (rank : 342)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	176	Target Neighborhood Hits	145	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

CT175_HUMAN
NC score	0.020707 (rank : 343)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	176	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MK2, Q5QPB6, Q9NQQ2	Gene names	C20orf175
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf175.

CK042_HUMAN
NC score	0.020284 (rank : 344)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	176	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5U0	Gene names	C11orf42
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf42.

SAPS1_HUMAN
NC score	0.020257 (rank : 345)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	176	Target Neighborhood Hits	704	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

BAZ2A_MOUSE
NC score	0.020249 (rank : 346)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	176	Target Neighborhood Hits	744	Shared Neighborhood Hits	27
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MAGC1_HUMAN
NC score	0.019982 (rank : 347)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	176	Target Neighborhood Hits	431	Shared Neighborhood Hits	23
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

LIPS_HUMAN
NC score	0.019034 (rank : 348)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	176	Target Neighborhood Hits	314	Shared Neighborhood Hits	18
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

SYBU_MOUSE
NC score	0.017709 (rank : 349)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	176	Target Neighborhood Hits	214	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

FMNL_MOUSE
NC score	0.017217 (rank : 350)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	176	Target Neighborhood Hits	428	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FA13C_MOUSE
NC score	0.015740 (rank : 351)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	176	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

IP3KC_HUMAN
NC score	0.015716 (rank : 352)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	176	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

DMRTD_HUMAN
NC score	0.015679 (rank : 353)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	176	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

TCP10_HUMAN
NC score	0.015134 (rank : 354)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	176	Target Neighborhood Hits	134	Shared Neighborhood Hits	17
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

DDX51_HUMAN
NC score	0.014948 (rank : 355)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	176	Target Neighborhood Hits	332	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

MDN1_HUMAN
NC score	0.014863 (rank : 356)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	176	Target Neighborhood Hits	662	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

KCD12_HUMAN
NC score	0.014636 (rank : 357)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	176	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

TP53B_HUMAN
NC score	0.014380 (rank : 358)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	176	Target Neighborhood Hits	413	Shared Neighborhood Hits	15
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SENP1_MOUSE
NC score	0.014235 (rank : 359)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	176	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

RTN1_HUMAN
NC score	0.012792 (rank : 360)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	176	Target Neighborhood Hits	173	Shared Neighborhood Hits	21
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

STAR8_HUMAN
NC score	0.011823 (rank : 361)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	176	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CHIC1_MOUSE
NC score	0.011228 (rank : 362)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	176	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CBW7, O08904, Q8K3S5	Gene names	Chic1, Brx
Domain Architecture	No domain graphic available
Description	Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein).

KCD12_MOUSE
NC score	0.010337 (rank : 363)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	176	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WVG3	Gene names	Kctd12, Pfet1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

RTN4_MOUSE
NC score	0.009132 (rank : 364)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	176	Target Neighborhood Hits	341	Shared Neighborhood Hits	12
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

REXO1_HUMAN
NC score	0.008477 (rank : 365)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	176	Target Neighborhood Hits	242	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

PITM3_MOUSE
NC score	0.008420 (rank : 366)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	176	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UHE1, Q3UH22, Q5RIT9	Gene names	Pitpnm3, Nir1
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1).

DNM1L_HUMAN
NC score	0.007617 (rank : 367)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	176	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

MA2A1_MOUSE
NC score	0.007487 (rank : 368)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	176	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

DLGP4_HUMAN
NC score	0.007329 (rank : 369)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	176	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

RBBP6_HUMAN
NC score	0.006826 (rank : 370)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	176	Target Neighborhood Hits	1135	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

PO3F2_MOUSE
NC score	0.004498 (rank : 371)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	176	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	P31360	Gene names	Pou3f2, Brn-2, Brn2, Otf7
Domain Architecture
Description	POU domain, class 3, transcription factor 2 (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Protein Brn-2).

TITIN_HUMAN
NC score	0.004069 (rank : 372)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	176	Target Neighborhood Hits	2923	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

RXRA_HUMAN
NC score	0.002979 (rank : 373)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	176	Target Neighborhood Hits	223	Shared Neighborhood Hits	6
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

ROBO1_HUMAN
NC score	0.002037 (rank : 374)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	176	Target Neighborhood Hits	529	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

SCN5A_HUMAN
NC score	0.001161 (rank : 375)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	176	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

HIC1_MOUSE
NC score	-0.005156 (rank : 376)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	176	Target Neighborhood Hits	863	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).