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Network neighborhood for query Sequence : STAR8_HUMAN

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STAR8_HUMAN
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RHG07_MOUSE
θ value	0 (rank : 1)	NC score	0.959941 (rank : 5)
Query Neighborhood Hits	216	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

STA13_HUMAN
θ value	0 (rank : 2)	NC score	0.960771 (rank : 4)
Query Neighborhood Hits	216	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
θ value	0 (rank : 3)	NC score	0.960890 (rank : 3)
Query Neighborhood Hits	216	Target Neighborhood Hits	89	Shared Neighborhood Hits	62
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STAR8_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	216	Target Neighborhood Hits	216	Shared Neighborhood Hits	216
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_MOUSE
θ value	0 (rank : 5)	NC score	0.986481 (rank : 2)
Query Neighborhood Hits	216	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG07_HUMAN
θ value	5.9077e-185 (rank : 6)	NC score	0.959420 (rank : 6)
Query Neighborhood Hits	216	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG06_MOUSE
θ value	1.99529e-15 (rank : 7)	NC score	0.692564 (rank : 9)
Query Neighborhood Hits	216	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

MYO9B_HUMAN
θ value	3.40345e-15 (rank : 8)	NC score	0.344461 (rank : 56)
Query Neighborhood Hits	216	Target Neighborhood Hits	641	Shared Neighborhood Hits	92
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RHG06_HUMAN
θ value	3.40345e-15 (rank : 9)	NC score	0.691475 (rank : 10)
Query Neighborhood Hits	216	Target Neighborhood Hits	114	Shared Neighborhood Hits	65
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_HUMAN
θ value	1.68911e-14 (rank : 10)	NC score	0.665215 (rank : 12)
Query Neighborhood Hits	216	Target Neighborhood Hits	376	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

MYO9B_MOUSE
θ value	1.68911e-14 (rank : 11)	NC score	0.345034 (rank : 55)
Query Neighborhood Hits	216	Target Neighborhood Hits	311	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RHG18_MOUSE
θ value	2.88119e-14 (rank : 12)	NC score	0.707968 (rank : 7)
Query Neighborhood Hits	216	Target Neighborhood Hits	110	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG04_HUMAN
θ value	3.76295e-14 (rank : 13)	NC score	0.594801 (rank : 22)
Query Neighborhood Hits	216	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

GRLF1_HUMAN
θ value	2.43908e-13 (rank : 14)	NC score	0.630933 (rank : 13)
Query Neighborhood Hits	216	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RBP1_MOUSE
θ value	9.26847e-13 (rank : 15)	NC score	0.606094 (rank : 21)
Query Neighborhood Hits	216	Target Neighborhood Hits	493	Shared Neighborhood Hits	66
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

3BP1_MOUSE
θ value	2.0648e-12 (rank : 16)	NC score	0.674862 (rank : 11)
Query Neighborhood Hits	216	Target Neighborhood Hits	238	Shared Neighborhood Hits	74
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG18_HUMAN
θ value	2.0648e-12 (rank : 17)	NC score	0.697666 (rank : 8)
Query Neighborhood Hits	216	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

ABR_HUMAN
θ value	7.84624e-12 (rank : 18)	NC score	0.575175 (rank : 27)
Query Neighborhood Hits	216	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

BCR_HUMAN
θ value	5.08577e-11 (rank : 19)	NC score	0.562763 (rank : 35)
Query Neighborhood Hits	216	Target Neighborhood Hits	204	Shared Neighborhood Hits	66
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RBP1_HUMAN
θ value	5.08577e-11 (rank : 20)	NC score	0.583088 (rank : 24)
Query Neighborhood Hits	216	Target Neighborhood Hits	521	Shared Neighborhood Hits	64
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP2_HUMAN
θ value	6.64225e-11 (rank : 21)	NC score	0.565401 (rank : 31)
Query Neighborhood Hits	216	Target Neighborhood Hits	331	Shared Neighborhood Hits	69
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

CE005_MOUSE
θ value	1.133e-10 (rank : 22)	NC score	0.528099 (rank : 48)
Query Neighborhood Hits	216	Target Neighborhood Hits	238	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE005_HUMAN
θ value	1.9326e-10 (rank : 23)	NC score	0.528724 (rank : 47)
Query Neighborhood Hits	216	Target Neighborhood Hits	213	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RGAP1_HUMAN
θ value	1.9326e-10 (rank : 24)	NC score	0.608755 (rank : 20)
Query Neighborhood Hits	216	Target Neighborhood Hits	189	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG01_HUMAN
θ value	4.30538e-10 (rank : 25)	NC score	0.620849 (rank : 15)
Query Neighborhood Hits	216	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

TCGAP_HUMAN
θ value	4.30538e-10 (rank : 26)	NC score	0.533570 (rank : 46)
Query Neighborhood Hits	216	Target Neighborhood Hits	872	Shared Neighborhood Hits	103
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	4.30538e-10 (rank : 27)	NC score	0.594655 (rank : 23)
Query Neighborhood Hits	216	Target Neighborhood Hits	409	Shared Neighborhood Hits	78
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GMIP_MOUSE
θ value	7.34386e-10 (rank : 28)	NC score	0.622768 (rank : 14)
Query Neighborhood Hits	216	Target Neighborhood Hits	202	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

SRGP2_MOUSE
θ value	7.34386e-10 (rank : 29)	NC score	0.555815 (rank : 36)
Query Neighborhood Hits	216	Target Neighborhood Hits	324	Shared Neighborhood Hits	68
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

FNBP2_HUMAN
θ value	9.59137e-10 (rank : 30)	NC score	0.547540 (rank : 41)
Query Neighborhood Hits	216	Target Neighborhood Hits	432	Shared Neighborhood Hits	69
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

CEND3_MOUSE
θ value	1.25267e-09 (rank : 31)	NC score	0.474670 (rank : 51)
Query Neighborhood Hits	216	Target Neighborhood Hits	228	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND2_HUMAN
θ value	1.63604e-09 (rank : 32)	NC score	0.487303 (rank : 50)
Query Neighborhood Hits	216	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RHG26_HUMAN
θ value	1.63604e-09 (rank : 33)	NC score	0.552719 (rank : 37)
Query Neighborhood Hits	216	Target Neighborhood Hits	281	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG12_HUMAN
θ value	2.13673e-09 (rank : 34)	NC score	0.618585 (rank : 16)
Query Neighborhood Hits	216	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SRGP1_HUMAN
θ value	2.13673e-09 (rank : 35)	NC score	0.542021 (rank : 45)
Query Neighborhood Hits	216	Target Neighborhood Hits	390	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

GMIP_HUMAN
θ value	3.64472e-09 (rank : 36)	NC score	0.617753 (rank : 17)
Query Neighborhood Hits	216	Target Neighborhood Hits	225	Shared Neighborhood Hits	63
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG12_MOUSE
θ value	3.64472e-09 (rank : 37)	NC score	0.614247 (rank : 19)
Query Neighborhood Hits	216	Target Neighborhood Hits	204	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CEND3_HUMAN
θ value	6.21693e-09 (rank : 38)	NC score	0.463130 (rank : 52)
Query Neighborhood Hits	216	Target Neighborhood Hits	275	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CHIN_HUMAN
θ value	6.21693e-09 (rank : 39)	NC score	0.549505 (rank : 40)
Query Neighborhood Hits	216	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_MOUSE
θ value	6.21693e-09 (rank : 40)	NC score	0.573912 (rank : 28)
Query Neighborhood Hits	216	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_HUMAN
θ value	1.80886e-08 (rank : 41)	NC score	0.544330 (rank : 43)
Query Neighborhood Hits	216	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_MOUSE
θ value	2.36244e-08 (rank : 42)	NC score	0.544993 (rank : 42)
Query Neighborhood Hits	216	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG05_MOUSE
θ value	1.53129e-07 (rank : 43)	NC score	0.563069 (rank : 34)
Query Neighborhood Hits	216	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG25_MOUSE
θ value	1.53129e-07 (rank : 44)	NC score	0.542077 (rank : 44)
Query Neighborhood Hits	216	Target Neighborhood Hits	492	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

OPHN1_MOUSE
θ value	2.61198e-07 (rank : 45)	NC score	0.568100 (rank : 29)
Query Neighborhood Hits	216	Target Neighborhood Hits	174	Shared Neighborhood Hits	61
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RGAP1_MOUSE
θ value	4.45536e-07 (rank : 46)	NC score	0.579462 (rank : 25)
Query Neighborhood Hits	216	Target Neighborhood Hits	185	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

NFH_MOUSE
θ value	5.81887e-07 (rank : 47)	NC score	0.045744 (rank : 80)
Query Neighborhood Hits	216	Target Neighborhood Hits	2247	Shared Neighborhood Hits	101
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RHG25_HUMAN
θ value	7.59969e-07 (rank : 48)	NC score	0.527856 (rank : 49)
Query Neighborhood Hits	216	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

OPHN1_HUMAN
θ value	9.92553e-07 (rank : 49)	NC score	0.564686 (rank : 33)
Query Neighborhood Hits	216	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG05_HUMAN
θ value	1.29631e-06 (rank : 50)	NC score	0.552230 (rank : 38)
Query Neighborhood Hits	216	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG09_HUMAN
θ value	1.29631e-06 (rank : 51)	NC score	0.614330 (rank : 18)
Query Neighborhood Hits	216	Target Neighborhood Hits	186	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG08_MOUSE
θ value	4.92598e-06 (rank : 52)	NC score	0.579198 (rank : 26)
Query Neighborhood Hits	216	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

TAGAP_HUMAN
θ value	1.43324e-05 (rank : 53)	NC score	0.565363 (rank : 32)
Query Neighborhood Hits	216	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG08_HUMAN
θ value	2.44474e-05 (rank : 54)	NC score	0.567604 (rank : 30)
Query Neighborhood Hits	216	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

PCTL_HUMAN
θ value	4.1701e-05 (rank : 55)	NC score	0.311667 (rank : 60)
Query Neighborhood Hits	216	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	4.1701e-05 (rank : 56)	NC score	0.314254 (rank : 59)
Query Neighborhood Hits	216	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

TAGAP_MOUSE
θ value	0.000602161 (rank : 57)	NC score	0.551383 (rank : 39)
Query Neighborhood Hits	216	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

STAR7_HUMAN
θ value	0.00134147 (rank : 58)	NC score	0.190616 (rank : 65)
Query Neighborhood Hits	216	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQZ5, Q6GU43, Q969M6	Gene names	STARD7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7) (Protein GTT1).

STAR7_MOUSE
θ value	0.00390308 (rank : 59)	NC score	0.173497 (rank : 66)
Query Neighborhood Hits	216	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R1R3	Gene names	Stard7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7).

P85A_MOUSE
θ value	0.00869519 (rank : 60)	NC score	0.251248 (rank : 62)
Query Neighborhood Hits	216	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_HUMAN
θ value	0.0252991 (rank : 61)	NC score	0.253519 (rank : 61)
Query Neighborhood Hits	216	Target Neighborhood Hits	479	Shared Neighborhood Hits	63
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

EFS_HUMAN
θ value	0.0330416 (rank : 62)	NC score	0.067730 (rank : 68)
Query Neighborhood Hits	216	Target Neighborhood Hits	348	Shared Neighborhood Hits	33
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

OGFR_HUMAN
θ value	0.0330416 (rank : 63)	NC score	0.048375 (rank : 77)
Query Neighborhood Hits	216	Target Neighborhood Hits	1582	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

AFF3_HUMAN
θ value	0.0736092 (rank : 64)	NC score	0.031256 (rank : 103)
Query Neighborhood Hits	216	Target Neighborhood Hits	190	Shared Neighborhood Hits	13
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

I5P2_HUMAN
θ value	0.0736092 (rank : 65)	NC score	0.236760 (rank : 63)
Query Neighborhood Hits	216	Target Neighborhood Hits	86	Shared Neighborhood Hits	54
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

FIP1_HUMAN
θ value	0.0961366 (rank : 66)	NC score	0.044676 (rank : 81)
Query Neighborhood Hits	216	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

EFS_MOUSE
θ value	0.125558 (rank : 67)	NC score	0.058697 (rank : 72)
Query Neighborhood Hits	216	Target Neighborhood Hits	389	Shared Neighborhood Hits	38
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

K1688_MOUSE
θ value	0.163984 (rank : 68)	NC score	0.397043 (rank : 53)
Query Neighborhood Hits	216	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
θ value	0.21417 (rank : 69)	NC score	0.385718 (rank : 54)
Query Neighborhood Hits	216	Target Neighborhood Hits	217	Shared Neighborhood Hits	67
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MLL2_HUMAN
θ value	0.21417 (rank : 70)	NC score	0.030698 (rank : 104)
Query Neighborhood Hits	216	Target Neighborhood Hits	1788	Shared Neighborhood Hits	69
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RAPH1_HUMAN
θ value	0.21417 (rank : 71)	NC score	0.040736 (rank : 86)
Query Neighborhood Hits	216	Target Neighborhood Hits	593	Shared Neighborhood Hits	43
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

BSN_MOUSE
θ value	0.279714 (rank : 72)	NC score	0.038777 (rank : 91)
Query Neighborhood Hits	216	Target Neighborhood Hits	2057	Shared Neighborhood Hits	94
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CENG1_HUMAN
θ value	0.279714 (rank : 73)	NC score	0.042890 (rank : 84)
Query Neighborhood Hits	216	Target Neighborhood Hits	544	Shared Neighborhood Hits	26
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	0.279714 (rank : 74)	NC score	0.046205 (rank : 79)
Query Neighborhood Hits	216	Target Neighborhood Hits	531	Shared Neighborhood Hits	29
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

RPO3D_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.041156 (rank : 85)
Query Neighborhood Hits	216	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P05423, Q6FI28, Q9BPV7, Q9BPZ1, Q9BXB3	Gene names	POLR3D, BN51, BN51T
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4) (RPC53) (Protein BN51).

TEX2_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.029514 (rank : 108)
Query Neighborhood Hits	216	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

ZN385_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.033159 (rank : 99)
Query Neighborhood Hits	216	Target Neighborhood Hits	614	Shared Neighborhood Hits	38
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CELR3_HUMAN
θ value	0.365318 (rank : 78)	NC score	0.001422 (rank : 211)
Query Neighborhood Hits	216	Target Neighborhood Hits	680	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

RCOR3_HUMAN
θ value	0.365318 (rank : 79)	NC score	0.024922 (rank : 114)
Query Neighborhood Hits	216	Target Neighborhood Hits	161	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

SFRS8_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.044657 (rank : 82)
Query Neighborhood Hits	216	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

ZN447_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.004541 (rank : 199)
Query Neighborhood Hits	216	Target Neighborhood Hits	899	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

NR6A1_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.012234 (rank : 161)
Query Neighborhood Hits	216	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

SSH1_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.014464 (rank : 146)
Query Neighborhood Hits	216	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

ACO12_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.051541 (rank : 73)
Query Neighborhood Hits	216	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYK0	Gene names	ACOT12, CACH, CACH1, STARD12
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 12) (StARD12).

CGRE1_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.035311 (rank : 94)
Query Neighborhood Hits	216	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

HUWE1_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.016138 (rank : 138)
Query Neighborhood Hits	216	Target Neighborhood Hits	443	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

PGCA_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.012468 (rank : 159)
Query Neighborhood Hits	216	Target Neighborhood Hits	821	Shared Neighborhood Hits	29
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

TOPB1_MOUSE
θ value	0.62314 (rank : 88)	NC score	0.025847 (rank : 112)
Query Neighborhood Hits	216	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

DMN_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.015082 (rank : 143)
Query Neighborhood Hits	216	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

FOG1_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.009371 (rank : 171)
Query Neighborhood Hits	216	Target Neighborhood Hits	981	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

RCOR3_MOUSE
θ value	0.813845 (rank : 91)	NC score	0.024184 (rank : 117)
Query Neighborhood Hits	216	Target Neighborhood Hits	110	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RREB1_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.004882 (rank : 196)
Query Neighborhood Hits	216	Target Neighborhood Hits	879	Shared Neighborhood Hits	32
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

CGRE1_MOUSE
θ value	1.06291 (rank : 93)	NC score	0.036534 (rank : 93)
Query Neighborhood Hits	216	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CT075_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.009228 (rank : 172)
Query Neighborhood Hits	216	Target Neighborhood Hits	358	Shared Neighborhood Hits	11
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

DAAM2_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.015962 (rank : 139)
Query Neighborhood Hits	216	Target Neighborhood Hits	371	Shared Neighborhood Hits	12
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

ICAL_MOUSE
θ value	1.06291 (rank : 96)	NC score	0.029820 (rank : 107)
Query Neighborhood Hits	216	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

MYCB2_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.023095 (rank : 121)
Query Neighborhood Hits	216	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NEK3_MOUSE
θ value	1.06291 (rank : 98)	NC score	-0.002988 (rank : 220)
Query Neighborhood Hits	216	Target Neighborhood Hits	854	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

SELPL_MOUSE
θ value	1.06291 (rank : 99)	NC score	0.050017 (rank : 74)
Query Neighborhood Hits	216	Target Neighborhood Hits	588	Shared Neighborhood Hits	58
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SEPT9_HUMAN
θ value	1.06291 (rank : 100)	NC score	0.023591 (rank : 120)
Query Neighborhood Hits	216	Target Neighborhood Hits	706	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SRRM2_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.040165 (rank : 87)
Query Neighborhood Hits	216	Target Neighborhood Hits	1296	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

A20A2_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.013446 (rank : 150)
Query Neighborhood Hits	216	Target Neighborhood Hits	716	Shared Neighborhood Hits	15
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ACO11_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.049690 (rank : 75)
Query Neighborhood Hits	216	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXI4, O75187, Q96DI1, Q9H883	Gene names	ACOT11, BFIT, KIAA0707, THEA
Domain Architecture
Description	Acyl-coenzyme A thioesterase 11 (EC 3.1.2.-) (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Brown fat-inducible thioesterase) (BFIT) (Adipose-associated thioesterase).

ANR35_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.011555 (rank : 166)
Query Neighborhood Hits	216	Target Neighborhood Hits	784	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

MLL4_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.032025 (rank : 101)
Query Neighborhood Hits	216	Target Neighborhood Hits	722	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NR6A1_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.010835 (rank : 169)
Query Neighborhood Hits	216	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

PHC1_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.018444 (rank : 131)
Query Neighborhood Hits	216	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	Q64028, P70359, Q64307, Q8BZ80	Gene names	Phc1, Edr, Edr1, Rae28
Domain Architecture
Description	Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28).

SPRR3_MOUSE
θ value	1.38821 (rank : 108)	NC score	0.024520 (rank : 116)
Query Neighborhood Hits	216	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

TTBK2_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.006247 (rank : 186)
Query Neighborhood Hits	216	Target Neighborhood Hits	822	Shared Neighborhood Hits	18
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

TTBK2_MOUSE
θ value	1.38821 (rank : 110)	NC score	0.006108 (rank : 187)
Query Neighborhood Hits	216	Target Neighborhood Hits	811	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

TTLL4_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.013142 (rank : 152)
Query Neighborhood Hits	216	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

A20A1_HUMAN
θ value	1.81305 (rank : 112)	NC score	0.012617 (rank : 158)
Query Neighborhood Hits	216	Target Neighborhood Hits	698	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A3_HUMAN
θ value	1.81305 (rank : 113)	NC score	0.012622 (rank : 157)
Query Neighborhood Hits	216	Target Neighborhood Hits	692	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.012428 (rank : 160)
Query Neighborhood Hits	216	Target Neighborhood Hits	710	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

MAGE1_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.028067 (rank : 110)
Query Neighborhood Hits	216	Target Neighborhood Hits	1389	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP4_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.026194 (rank : 111)
Query Neighborhood Hits	216	Target Neighborhood Hits	409	Shared Neighborhood Hits	33
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SOX13_MOUSE
θ value	1.81305 (rank : 117)	NC score	0.014025 (rank : 147)
Query Neighborhood Hits	216	Target Neighborhood Hits	495	Shared Neighborhood Hits	31
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

TACC3_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.023067 (rank : 122)
Query Neighborhood Hits	216	Target Neighborhood Hits	779	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

WBS14_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.028956 (rank : 109)
Query Neighborhood Hits	216	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ACO12_MOUSE
θ value	2.36792 (rank : 120)	NC score	0.067741 (rank : 67)
Query Neighborhood Hits	216	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBK0, Q544M5, Q8R108	Gene names	Acot12, Cach, Cach1
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (mCACH-1).

ARHG1_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.011823 (rank : 163)
Query Neighborhood Hits	216	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

CS016_HUMAN
θ value	2.36792 (rank : 122)	NC score	0.044498 (rank : 83)
Query Neighborhood Hits	216	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

PLCB2_HUMAN
θ value	2.36792 (rank : 123)	NC score	0.012677 (rank : 155)
Query Neighborhood Hits	216	Target Neighborhood Hits	608	Shared Neighborhood Hits	12
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

PRGC2_MOUSE
θ value	2.36792 (rank : 124)	NC score	0.016414 (rank : 136)
Query Neighborhood Hits	216	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PRR12_HUMAN
θ value	2.36792 (rank : 125)	NC score	0.040049 (rank : 89)
Query Neighborhood Hits	216	Target Neighborhood Hits	460	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

REPS2_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.015712 (rank : 141)
Query Neighborhood Hits	216	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

RPO3D_MOUSE
θ value	2.36792 (rank : 127)	NC score	0.032572 (rank : 100)
Query Neighborhood Hits	216	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WD1, Q9CZ02	Gene names	Polr3d, Bn51t
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4).

SRBS1_MOUSE
θ value	2.36792 (rank : 128)	NC score	0.048817 (rank : 76)
Query Neighborhood Hits	216	Target Neighborhood Hits	409	Shared Neighborhood Hits	32
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

DDIT3_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.018579 (rank : 129)
Query Neighborhood Hits	216	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

DTX1_MOUSE
θ value	3.0926 (rank : 130)	NC score	0.014583 (rank : 145)
Query Neighborhood Hits	216	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

LRC24_MOUSE
θ value	3.0926 (rank : 131)	NC score	0.001587 (rank : 210)
Query Neighborhood Hits	216	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

NR1H2_HUMAN
θ value	3.0926 (rank : 132)	NC score	0.005360 (rank : 194)
Query Neighborhood Hits	216	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

PELP1_MOUSE
θ value	3.0926 (rank : 133)	NC score	0.031851 (rank : 102)
Query Neighborhood Hits	216	Target Neighborhood Hits	709	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PRRT3_HUMAN
θ value	3.0926 (rank : 134)	NC score	0.035261 (rank : 95)
Query Neighborhood Hits	216	Target Neighborhood Hits	998	Shared Neighborhood Hits	69
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RU17_MOUSE
θ value	3.0926 (rank : 135)	NC score	0.008803 (rank : 174)
Query Neighborhood Hits	216	Target Neighborhood Hits	278	Shared Neighborhood Hits	8
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

SET1A_HUMAN
θ value	3.0926 (rank : 136)	NC score	0.033545 (rank : 98)
Query Neighborhood Hits	216	Target Neighborhood Hits	690	Shared Neighborhood Hits	40
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ANR38_MOUSE
θ value	4.03905 (rank : 137)	NC score	0.006626 (rank : 184)
Query Neighborhood Hits	216	Target Neighborhood Hits	512	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

APS_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.017917 (rank : 132)
Query Neighborhood Hits	216	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

BRWD1_MOUSE
θ value	4.03905 (rank : 139)	NC score	0.003356 (rank : 204)
Query Neighborhood Hits	216	Target Neighborhood Hits	478	Shared Neighborhood Hits	14
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

DYR1B_HUMAN
θ value	4.03905 (rank : 140)	NC score	-0.002345 (rank : 217)
Query Neighborhood Hits	216	Target Neighborhood Hits	831	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

FOXI1_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.005005 (rank : 195)
Query Neighborhood Hits	216	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q12951, Q14518, Q66SR7, Q8N6L8	Gene names	FOXI1, FKHL10, FREAC6
Domain Architecture
Description	Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead- related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HNF-3/fork-head homolog 3) (HFH-3).

FREM3_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.005893 (rank : 190)
Query Neighborhood Hits	216	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

KCNA5_MOUSE
θ value	4.03905 (rank : 143)	NC score	0.003034 (rank : 206)
Query Neighborhood Hits	216	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

MAGD2_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.008176 (rank : 176)
Query Neighborhood Hits	216	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UNF1, O76058, Q5BJF3, Q8NAL6, Q9H218, Q9P0U9, Q9UM52	Gene names	MAGED2, BCG1
Domain Architecture
Description	Melanoma-associated antigen D2 (MAGE-D2 antigen) (MAGE-D) (Breast cancer-associated gene 1 protein) (BCG-1) (11B6) (Hepatocellular carcinoma-associated protein JCL-1).

MILK1_MOUSE
θ value	4.03905 (rank : 145)	NC score	0.023970 (rank : 118)
Query Neighborhood Hits	216	Target Neighborhood Hits	788	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

OTP_MOUSE
θ value	4.03905 (rank : 146)	NC score	0.000840 (rank : 212)
Query Neighborhood Hits	216	Target Neighborhood Hits	387	Shared Neighborhood Hits	8
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

P2RX2_HUMAN
θ value	4.03905 (rank : 147)	NC score	0.011054 (rank : 168)
Query Neighborhood Hits	216	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

PCQAP_MOUSE
θ value	4.03905 (rank : 148)	NC score	0.023756 (rank : 119)
Query Neighborhood Hits	216	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

TCF20_HUMAN
θ value	4.03905 (rank : 149)	NC score	0.018784 (rank : 128)
Query Neighborhood Hits	216	Target Neighborhood Hits	323	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TLE3_HUMAN
θ value	4.03905 (rank : 150)	NC score	0.007396 (rank : 178)
Query Neighborhood Hits	216	Target Neighborhood Hits	385	Shared Neighborhood Hits	13
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

TLE3_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.007140 (rank : 180)
Query Neighborhood Hits	216	Target Neighborhood Hits	378	Shared Neighborhood Hits	9
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

UBP36_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.008410 (rank : 175)
Query Neighborhood Hits	216	Target Neighborhood Hits	232	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

ULK1_HUMAN
θ value	4.03905 (rank : 153)	NC score	-0.000659 (rank : 214)
Query Neighborhood Hits	216	Target Neighborhood Hits	1121	Shared Neighborhood Hits	31
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

41_MOUSE
θ value	5.27518 (rank : 154)	NC score	0.004206 (rank : 203)
Query Neighborhood Hits	216	Target Neighborhood Hits	184	Shared Neighborhood Hits	9
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

ADDA_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.013951 (rank : 148)
Query Neighborhood Hits	216	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

ALEX_MOUSE
θ value	5.27518 (rank : 156)	NC score	0.025260 (rank : 113)
Query Neighborhood Hits	216	Target Neighborhood Hits	197	Shared Neighborhood Hits	23
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ALKB5_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.012692 (rank : 153)
Query Neighborhood Hits	216	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P6C2, Q9NXD6	Gene names	ALKBH5
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 5.

ARI1B_HUMAN
θ value	5.27518 (rank : 158)	NC score	0.022161 (rank : 124)
Query Neighborhood Hits	216	Target Neighborhood Hits	567	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ATBF1_MOUSE
θ value	5.27518 (rank : 159)	NC score	0.002961 (rank : 207)
Query Neighborhood Hits	216	Target Neighborhood Hits	1841	Shared Neighborhood Hits	48
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CATZ_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.006500 (rank : 185)
Query Neighborhood Hits	216	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBR2, O75331, Q9UQV5, Q9UQV6	Gene names	CTSZ
Domain Architecture
Description	Cathepsin Z precursor (EC 3.4.22.-) (Cathepsin X) (Cathepsin P).

DAAM2_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.011740 (rank : 164)
Query Neighborhood Hits	216	Target Neighborhood Hits	350	Shared Neighborhood Hits	9
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DDEF2_MOUSE
θ value	5.27518 (rank : 162)	NC score	0.040060 (rank : 88)
Query Neighborhood Hits	216	Target Neighborhood Hits	625	Shared Neighborhood Hits	35
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DNMBP_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.034813 (rank : 97)
Query Neighborhood Hits	216	Target Neighborhood Hits	435	Shared Neighborhood Hits	30
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ES8L1_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.008842 (rank : 173)
Query Neighborhood Hits	216	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

FOXC2_HUMAN
θ value	5.27518 (rank : 165)	NC score	0.007137 (rank : 181)
Query Neighborhood Hits	216	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

HPS4_MOUSE
θ value	5.27518 (rank : 166)	NC score	0.012649 (rank : 156)
Query Neighborhood Hits	216	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

INCE_HUMAN
θ value	5.27518 (rank : 167)	NC score	0.004440 (rank : 201)
Query Neighborhood Hits	216	Target Neighborhood Hits	978	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INP5E_HUMAN
θ value	5.27518 (rank : 168)	NC score	0.015850 (rank : 140)
Query Neighborhood Hits	216	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

K0141_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.011584 (rank : 165)
Query Neighborhood Hits	216	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q14154, Q969R4, Q96EU9	Gene names	KIAA0141
Domain Architecture
Description	Protein KIAA0141.

MINT_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.016263 (rank : 137)
Query Neighborhood Hits	216	Target Neighborhood Hits	1291	Shared Neighborhood Hits	48
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MNT_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.017747 (rank : 133)
Query Neighborhood Hits	216	Target Neighborhood Hits	496	Shared Neighborhood Hits	33
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NCOR2_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.024669 (rank : 115)
Query Neighborhood Hits	216	Target Neighborhood Hits	870	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ODO2_MOUSE
θ value	5.27518 (rank : 173)	NC score	0.016640 (rank : 135)
Query Neighborhood Hits	216	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

SRRM1_MOUSE
θ value	5.27518 (rank : 174)	NC score	0.039014 (rank : 90)
Query Neighborhood Hits	216	Target Neighborhood Hits	966	Shared Neighborhood Hits	59
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TBX3_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.005726 (rank : 191)
Query Neighborhood Hits	216	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TSH3_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.008009 (rank : 177)
Query Neighborhood Hits	216	Target Neighborhood Hits	564	Shared Neighborhood Hits	15
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

3BP2_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.029874 (rank : 106)
Query Neighborhood Hits	216	Target Neighborhood Hits	142	Shared Neighborhood Hits	19
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ANR12_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.003266 (rank : 205)
Query Neighborhood Hits	216	Target Neighborhood Hits	1081	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CAC1H_HUMAN
θ value	6.88961 (rank : 179)	NC score	0.007011 (rank : 183)
Query Neighborhood Hits	216	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAN3_MOUSE
θ value	6.88961 (rank : 180)	NC score	0.002439 (rank : 209)
Query Neighborhood Hits	216	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CO039_MOUSE
θ value	6.88961 (rank : 181)	NC score	0.022750 (rank : 123)
Query Neighborhood Hits	216	Target Neighborhood Hits	445	Shared Neighborhood Hits	39
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

EP400_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.009510 (rank : 170)
Query Neighborhood Hits	216	Target Neighborhood Hits	556	Shared Neighborhood Hits	30
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FIP1_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.029899 (rank : 105)
Query Neighborhood Hits	216	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

FOXB1_HUMAN
θ value	6.88961 (rank : 184)	NC score	0.004692 (rank : 198)
Query Neighborhood Hits	216	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q99853, O60652, O75917	Gene names	FOXB1, FKH5
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

FOXB1_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.004751 (rank : 197)
Query Neighborhood Hits	216	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q64732, O08753	Gene names	Foxb1, Fkh5, Foxb1a, Foxb1b, Mf3
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

GNDS_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.012689 (rank : 154)
Query Neighborhood Hits	216	Target Neighborhood Hits	201	Shared Neighborhood Hits	22
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

KCNQ1_MOUSE
θ value	6.88961 (rank : 187)	NC score	0.004492 (rank : 200)
Query Neighborhood Hits	216	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

MMTA2_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.015249 (rank : 142)
Query Neighborhood Hits	216	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BU76, Q6P5Y0, Q6ZTZ6, Q6ZWA6, Q8IZH3	Gene names	MMTAG2, C1orf35
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 (hMMTAG2).

NFRKB_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.017132 (rank : 134)
Query Neighborhood Hits	216	Target Neighborhood Hits	211	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PRDM2_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.002811 (rank : 208)
Query Neighborhood Hits	216	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SLIK1_HUMAN
θ value	6.88961 (rank : 191)	NC score	0.000525 (rank : 213)
Query Neighborhood Hits	216	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

SRRM2_MOUSE
θ value	6.88961 (rank : 192)	NC score	0.034994 (rank : 96)
Query Neighborhood Hits	216	Target Neighborhood Hits	1470	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TF65_MOUSE
θ value	6.88961 (rank : 193)	NC score	0.005673 (rank : 192)
Query Neighborhood Hits	216	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TIEG3_MOUSE
θ value	6.88961 (rank : 194)	NC score	-0.002972 (rank : 219)
Query Neighborhood Hits	216	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

TSSC4_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.014791 (rank : 144)
Query Neighborhood Hits	216	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5U2, Q86VL2, Q9BRS6	Gene names	TSSC4
Domain Architecture	No domain graphic available
Description	Protein TSSC4 (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) (Tumor-suppressing STF cDNA 4 protein).

CCDC7_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.007354 (rank : 179)
Query Neighborhood Hits	216	Target Neighborhood Hits	253	Shared Neighborhood Hits	6
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

CUTL1_MOUSE
θ value	8.99809 (rank : 197)	NC score	0.012070 (rank : 162)
Query Neighborhood Hits	216	Target Neighborhood Hits	1620	Shared Neighborhood Hits	58
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DUET_HUMAN
θ value	8.99809 (rank : 198)	NC score	-0.001221 (rank : 215)
Query Neighborhood Hits	216	Target Neighborhood Hits	1220	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

E2F4_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.011149 (rank : 167)
Query Neighborhood Hits	216	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

ETV6_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.004213 (rank : 202)
Query Neighborhood Hits	216	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

IF35_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.018846 (rank : 127)
Query Neighborhood Hits	216	Target Neighborhood Hits	210	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IRAK1_MOUSE
θ value	8.99809 (rank : 202)	NC score	-0.002874 (rank : 218)
Query Neighborhood Hits	216	Target Neighborhood Hits	784	Shared Neighborhood Hits	14
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

NACAM_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.037110 (rank : 92)
Query Neighborhood Hits	216	Target Neighborhood Hits	1866	Shared Neighborhood Hits	96
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OLIG1_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.005374 (rank : 193)
Query Neighborhood Hits	216	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

PHF12_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.005939 (rank : 189)
Query Neighborhood Hits	216	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKN3_MOUSE
θ value	8.99809 (rank : 206)	NC score	-0.004557 (rank : 221)
Query Neighborhood Hits	216	Target Neighborhood Hits	1009	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

RBBP6_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.013738 (rank : 149)
Query Neighborhood Hits	216	Target Neighborhood Hits	1014	Shared Neighborhood Hits	32
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RU17_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.005981 (rank : 188)
Query Neighborhood Hits	216	Target Neighborhood Hits	280	Shared Neighborhood Hits	7
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

SGIP1_HUMAN
θ value	8.99809 (rank : 209)	NC score	0.019590 (rank : 126)
Query Neighborhood Hits	216	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SON_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.021099 (rank : 125)
Query Neighborhood Hits	216	Target Neighborhood Hits	957	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRBS1_HUMAN
θ value	8.99809 (rank : 211)	NC score	0.046871 (rank : 78)
Query Neighborhood Hits	216	Target Neighborhood Hits	396	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYN2_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.013385 (rank : 151)
Query Neighborhood Hits	216	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TARA_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.018554 (rank : 130)
Query Neighborhood Hits	216	Target Neighborhood Hits	1626	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TIF1G_MOUSE
θ value	8.99809 (rank : 214)	NC score	0.007119 (rank : 182)
Query Neighborhood Hits	216	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

WNK1_HUMAN
θ value	8.99809 (rank : 215)	NC score	-0.001289 (rank : 216)
Query Neighborhood Hits	216	Target Neighborhood Hits	1158	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZNF79_HUMAN
θ value	8.99809 (rank : 216)	NC score	-0.005428 (rank : 222)
Query Neighborhood Hits	216	Target Neighborhood Hits	761	Shared Neighborhood Hits	9
SwissProt Accessions	Q15937, Q5VVW1, Q96NV1	Gene names	ZNF79
Domain Architecture	No domain graphic available
Description	Zinc finger protein 79 (ZNFpT7).

CEND1_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.320593 (rank : 58)
Query Neighborhood Hits	216	Target Neighborhood Hits	284	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.335249 (rank : 57)
Query Neighborhood Hits	216	Target Neighborhood Hits	260	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

FA13A_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.058915 (rank : 71)
Query Neighborhood Hits	216	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.059912 (rank : 69)
Query Neighborhood Hits	216	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

OCRL_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.200359 (rank : 64)
Query Neighborhood Hits	216	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85B_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.059822 (rank : 70)
Query Neighborhood Hits	216	Target Neighborhood Hits	543	Shared Neighborhood Hits	36
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

Hits sorted by NC score

STAR8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	216	Target Neighborhood Hits	216	Shared Neighborhood Hits	216
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_MOUSE
NC score	0.986481 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	216	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
NC score	0.960890 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	216	Target Neighborhood Hits	89	Shared Neighborhood Hits	62
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STA13_HUMAN
NC score	0.960771 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	216	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

RHG07_MOUSE
NC score	0.959941 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	216	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.959420 (rank : 6)	θ value	5.9077e-185 (rank : 6)
Query Neighborhood Hits	216	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG18_MOUSE
NC score	0.707968 (rank : 7)	θ value	2.88119e-14 (rank : 12)
Query Neighborhood Hits	216	Target Neighborhood Hits	110	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG18_HUMAN
NC score	0.697666 (rank : 8)	θ value	2.0648e-12 (rank : 17)
Query Neighborhood Hits	216	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG06_MOUSE
NC score	0.692564 (rank : 9)	θ value	1.99529e-15 (rank : 7)
Query Neighborhood Hits	216	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_HUMAN
NC score	0.691475 (rank : 10)	θ value	3.40345e-15 (rank : 9)
Query Neighborhood Hits	216	Target Neighborhood Hits	114	Shared Neighborhood Hits	65
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_MOUSE
NC score	0.674862 (rank : 11)	θ value	2.0648e-12 (rank : 16)
Query Neighborhood Hits	216	Target Neighborhood Hits	238	Shared Neighborhood Hits	74
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_HUMAN
NC score	0.665215 (rank : 12)	θ value	1.68911e-14 (rank : 10)
Query Neighborhood Hits	216	Target Neighborhood Hits	376	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GRLF1_HUMAN
NC score	0.630933 (rank : 13)	θ value	2.43908e-13 (rank : 14)
Query Neighborhood Hits	216	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

GMIP_MOUSE
NC score	0.622768 (rank : 14)	θ value	7.34386e-10 (rank : 28)
Query Neighborhood Hits	216	Target Neighborhood Hits	202	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG01_HUMAN
NC score	0.620849 (rank : 15)	θ value	4.30538e-10 (rank : 25)
Query Neighborhood Hits	216	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG12_HUMAN
NC score	0.618585 (rank : 16)	θ value	2.13673e-09 (rank : 34)
Query Neighborhood Hits	216	Target Neighborhood Hits	190	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

GMIP_HUMAN
NC score	0.617753 (rank : 17)	θ value	3.64472e-09 (rank : 36)
Query Neighborhood Hits	216	Target Neighborhood Hits	225	Shared Neighborhood Hits	63
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG09_HUMAN
NC score	0.614330 (rank : 18)	θ value	1.29631e-06 (rank : 51)
Query Neighborhood Hits	216	Target Neighborhood Hits	186	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_MOUSE
NC score	0.614247 (rank : 19)	θ value	3.64472e-09 (rank : 37)
Query Neighborhood Hits	216	Target Neighborhood Hits	204	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RGAP1_HUMAN
NC score	0.608755 (rank : 20)	θ value	1.9326e-10 (rank : 24)
Query Neighborhood Hits	216	Target Neighborhood Hits	189	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RBP1_MOUSE
NC score	0.606094 (rank : 21)	θ value	9.26847e-13 (rank : 15)
Query Neighborhood Hits	216	Target Neighborhood Hits	493	Shared Neighborhood Hits	66
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG04_HUMAN
NC score	0.594801 (rank : 22)	θ value	3.76295e-14 (rank : 13)
Query Neighborhood Hits	216	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

TCGAP_MOUSE
NC score	0.594655 (rank : 23)	θ value	4.30538e-10 (rank : 27)
Query Neighborhood Hits	216	Target Neighborhood Hits	409	Shared Neighborhood Hits	78
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RBP1_HUMAN
NC score	0.583088 (rank : 24)	θ value	5.08577e-11 (rank : 20)
Query Neighborhood Hits	216	Target Neighborhood Hits	521	Shared Neighborhood Hits	64
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_MOUSE
NC score	0.579462 (rank : 25)	θ value	4.45536e-07 (rank : 46)
Query Neighborhood Hits	216	Target Neighborhood Hits	185	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG08_MOUSE
NC score	0.579198 (rank : 26)	θ value	4.92598e-06 (rank : 52)
Query Neighborhood Hits	216	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

ABR_HUMAN
NC score	0.575175 (rank : 27)	θ value	7.84624e-12 (rank : 18)
Query Neighborhood Hits	216	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

CHIO_MOUSE
NC score	0.573912 (rank : 28)	θ value	6.21693e-09 (rank : 40)
Query Neighborhood Hits	216	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

OPHN1_MOUSE
NC score	0.568100 (rank : 29)	θ value	2.61198e-07 (rank : 45)
Query Neighborhood Hits	216	Target Neighborhood Hits	174	Shared Neighborhood Hits	61
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG08_HUMAN
NC score	0.567604 (rank : 30)	θ value	2.44474e-05 (rank : 54)
Query Neighborhood Hits	216	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

SRGP2_HUMAN
NC score	0.565401 (rank : 31)	θ value	6.64225e-11 (rank : 21)
Query Neighborhood Hits	216	Target Neighborhood Hits	331	Shared Neighborhood Hits	69
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

TAGAP_HUMAN
NC score	0.565363 (rank : 32)	θ value	1.43324e-05 (rank : 53)
Query Neighborhood Hits	216	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

OPHN1_HUMAN
NC score	0.564686 (rank : 33)	θ value	9.92553e-07 (rank : 49)
Query Neighborhood Hits	216	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG05_MOUSE
NC score	0.563069 (rank : 34)	θ value	1.53129e-07 (rank : 43)
Query Neighborhood Hits	216	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

BCR_HUMAN
NC score	0.562763 (rank : 35)	θ value	5.08577e-11 (rank : 19)
Query Neighborhood Hits	216	Target Neighborhood Hits	204	Shared Neighborhood Hits	66
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SRGP2_MOUSE
NC score	0.555815 (rank : 36)	θ value	7.34386e-10 (rank : 29)
Query Neighborhood Hits	216	Target Neighborhood Hits	324	Shared Neighborhood Hits	68
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG26_HUMAN
NC score	0.552719 (rank : 37)	θ value	1.63604e-09 (rank : 33)
Query Neighborhood Hits	216	Target Neighborhood Hits	281	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG05_HUMAN
NC score	0.552230 (rank : 38)	θ value	1.29631e-06 (rank : 50)
Query Neighborhood Hits	216	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

TAGAP_MOUSE
NC score	0.551383 (rank : 39)	θ value	0.000602161 (rank : 57)
Query Neighborhood Hits	216	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CHIN_HUMAN
NC score	0.549505 (rank : 40)	θ value	6.21693e-09 (rank : 39)
Query Neighborhood Hits	216	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

FNBP2_HUMAN
NC score	0.547540 (rank : 41)	θ value	9.59137e-10 (rank : 30)
Query Neighborhood Hits	216	Target Neighborhood Hits	432	Shared Neighborhood Hits	69
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

CHIN_MOUSE
NC score	0.544993 (rank : 42)	θ value	2.36244e-08 (rank : 42)
Query Neighborhood Hits	216	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
NC score	0.544330 (rank : 43)	θ value	1.80886e-08 (rank : 41)
Query Neighborhood Hits	216	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG25_MOUSE
NC score	0.542077 (rank : 44)	θ value	1.53129e-07 (rank : 44)
Query Neighborhood Hits	216	Target Neighborhood Hits	492	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRGP1_HUMAN
NC score	0.542021 (rank : 45)	θ value	2.13673e-09 (rank : 35)
Query Neighborhood Hits	216	Target Neighborhood Hits	390	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

TCGAP_HUMAN
NC score	0.533570 (rank : 46)	θ value	4.30538e-10 (rank : 26)
Query Neighborhood Hits	216	Target Neighborhood Hits	872	Shared Neighborhood Hits	103
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CE005_HUMAN
NC score	0.528724 (rank : 47)	θ value	1.9326e-10 (rank : 23)
Query Neighborhood Hits	216	Target Neighborhood Hits	213	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.528099 (rank : 48)	θ value	1.133e-10 (rank : 22)
Query Neighborhood Hits	216	Target Neighborhood Hits	238	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG25_HUMAN
NC score	0.527856 (rank : 49)	θ value	7.59969e-07 (rank : 48)
Query Neighborhood Hits	216	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CEND2_HUMAN
NC score	0.487303 (rank : 50)	θ value	1.63604e-09 (rank : 32)
Query Neighborhood Hits	216	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_MOUSE
NC score	0.474670 (rank : 51)	θ value	1.25267e-09 (rank : 31)
Query Neighborhood Hits	216	Target Neighborhood Hits	228	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.463130 (rank : 52)	θ value	6.21693e-09 (rank : 38)
Query Neighborhood Hits	216	Target Neighborhood Hits	275	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

K1688_MOUSE
NC score	0.397043 (rank : 53)	θ value	0.163984 (rank : 68)
Query Neighborhood Hits	216	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.385718 (rank : 54)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	216	Target Neighborhood Hits	217	Shared Neighborhood Hits	67
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MYO9B_MOUSE
NC score	0.345034 (rank : 55)	θ value	1.68911e-14 (rank : 11)
Query Neighborhood Hits	216	Target Neighborhood Hits	311	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.344461 (rank : 56)	θ value	3.40345e-15 (rank : 8)
Query Neighborhood Hits	216	Target Neighborhood Hits	641	Shared Neighborhood Hits	92
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CEND1_MOUSE
NC score	0.335249 (rank : 57)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	216	Target Neighborhood Hits	260	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.320593 (rank : 58)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	216	Target Neighborhood Hits	284	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

PCTL_MOUSE
NC score	0.314254 (rank : 59)	θ value	4.1701e-05 (rank : 56)
Query Neighborhood Hits	216	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.311667 (rank : 60)	θ value	4.1701e-05 (rank : 55)
Query Neighborhood Hits	216	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

P85A_HUMAN
NC score	0.253519 (rank : 61)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	216	Target Neighborhood Hits	479	Shared Neighborhood Hits	63
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.251248 (rank : 62)	θ value	0.00869519 (rank : 60)
Query Neighborhood Hits	216	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.236760 (rank : 63)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	216	Target Neighborhood Hits	86	Shared Neighborhood Hits	54
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.200359 (rank : 64)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	216	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

STAR7_HUMAN
NC score	0.190616 (rank : 65)	θ value	0.00134147 (rank : 58)
Query Neighborhood Hits	216	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQZ5, Q6GU43, Q969M6	Gene names	STARD7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7) (Protein GTT1).

STAR7_MOUSE
NC score	0.173497 (rank : 66)	θ value	0.00390308 (rank : 59)
Query Neighborhood Hits	216	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R1R3	Gene names	Stard7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7).

ACO12_MOUSE
NC score	0.067741 (rank : 67)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	216	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBK0, Q544M5, Q8R108	Gene names	Acot12, Cach, Cach1
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (mCACH-1).

EFS_HUMAN
NC score	0.067730 (rank : 68)	θ value	0.0330416 (rank : 62)
Query Neighborhood Hits	216	Target Neighborhood Hits	348	Shared Neighborhood Hits	33
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FA13A_MOUSE
NC score	0.059912 (rank : 69)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	216	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

P85B_HUMAN
NC score	0.059822 (rank : 70)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	216	Target Neighborhood Hits	543	Shared Neighborhood Hits	36
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

FA13A_HUMAN
NC score	0.058915 (rank : 71)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	216	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

EFS_MOUSE
NC score	0.058697 (rank : 72)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	216	Target Neighborhood Hits	389	Shared Neighborhood Hits	38
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ACO12_HUMAN
NC score	0.051541 (rank : 73)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	216	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYK0	Gene names	ACOT12, CACH, CACH1, STARD12
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 12) (StARD12).

SELPL_MOUSE
NC score	0.050017 (rank : 74)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	216	Target Neighborhood Hits	588	Shared Neighborhood Hits	58
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ACO11_HUMAN
NC score	0.049690 (rank : 75)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	216	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXI4, O75187, Q96DI1, Q9H883	Gene names	ACOT11, BFIT, KIAA0707, THEA
Domain Architecture
Description	Acyl-coenzyme A thioesterase 11 (EC 3.1.2.-) (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Brown fat-inducible thioesterase) (BFIT) (Adipose-associated thioesterase).

SRBS1_MOUSE
NC score	0.048817 (rank : 76)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	216	Target Neighborhood Hits	409	Shared Neighborhood Hits	32
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

OGFR_HUMAN
NC score	0.048375 (rank : 77)	θ value	0.0330416 (rank : 63)
Query Neighborhood Hits	216	Target Neighborhood Hits	1582	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SRBS1_HUMAN
NC score	0.046871 (rank : 78)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	216	Target Neighborhood Hits	396	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CENG1_MOUSE
NC score	0.046205 (rank : 79)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	216	Target Neighborhood Hits	531	Shared Neighborhood Hits	29
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

NFH_MOUSE
NC score	0.045744 (rank : 80)	θ value	5.81887e-07 (rank : 47)
Query Neighborhood Hits	216	Target Neighborhood Hits	2247	Shared Neighborhood Hits	101
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

FIP1_HUMAN
NC score	0.044676 (rank : 81)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	216	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

SFRS8_HUMAN
NC score	0.044657 (rank : 82)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	216	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

CS016_HUMAN
NC score	0.044498 (rank : 83)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	216	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CENG1_HUMAN
NC score	0.042890 (rank : 84)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	216	Target Neighborhood Hits	544	Shared Neighborhood Hits	26
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

RPO3D_HUMAN
NC score	0.041156 (rank : 85)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	216	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P05423, Q6FI28, Q9BPV7, Q9BPZ1, Q9BXB3	Gene names	POLR3D, BN51, BN51T
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4) (RPC53) (Protein BN51).

RAPH1_HUMAN
NC score	0.040736 (rank : 86)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	216	Target Neighborhood Hits	593	Shared Neighborhood Hits	43
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SRRM2_HUMAN
NC score	0.040165 (rank : 87)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	216	Target Neighborhood Hits	1296	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DDEF2_MOUSE
NC score	0.040060 (rank : 88)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	216	Target Neighborhood Hits	625	Shared Neighborhood Hits	35
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PRR12_HUMAN
NC score	0.040049 (rank : 89)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	216	Target Neighborhood Hits	460	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SRRM1_MOUSE
NC score	0.039014 (rank : 90)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	216	Target Neighborhood Hits	966	Shared Neighborhood Hits	59
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BSN_MOUSE
NC score	0.038777 (rank : 91)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	216	Target Neighborhood Hits	2057	Shared Neighborhood Hits	94
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NACAM_MOUSE
NC score	0.037110 (rank : 92)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	216	Target Neighborhood Hits	1866	Shared Neighborhood Hits	96
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CGRE1_MOUSE
NC score	0.036534 (rank : 93)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	216	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CGRE1_HUMAN
NC score	0.035311 (rank : 94)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	216	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

PRRT3_HUMAN
NC score	0.035261 (rank : 95)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	216	Target Neighborhood Hits	998	Shared Neighborhood Hits	69
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SRRM2_MOUSE
NC score	0.034994 (rank : 96)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	216	Target Neighborhood Hits	1470	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DNMBP_MOUSE
NC score	0.034813 (rank : 97)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	216	Target Neighborhood Hits	435	Shared Neighborhood Hits	30
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SET1A_HUMAN
NC score	0.033545 (rank : 98)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	216	Target Neighborhood Hits	690	Shared Neighborhood Hits	40
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ZN385_HUMAN
NC score	0.033159 (rank : 99)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	216	Target Neighborhood Hits	614	Shared Neighborhood Hits	38
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

RPO3D_MOUSE
NC score	0.032572 (rank : 100)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	216	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WD1, Q9CZ02	Gene names	Polr3d, Bn51t
Domain Architecture
Description	DNA-directed RNA polymerase III subunit D (EC 2.7.7.6) (DNA-directed RNA polymerase III 47 kDa polypeptide) (RNA polymerase C subunit 4) (RPC4).

MLL4_HUMAN
NC score	0.032025 (rank : 101)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	216	Target Neighborhood Hits	722	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PELP1_MOUSE
NC score	0.031851 (rank : 102)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	216	Target Neighborhood Hits	709	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

AFF3_HUMAN
NC score	0.031256 (rank : 103)	θ value	0.0736092 (rank : 64)
Query Neighborhood Hits	216	Target Neighborhood Hits	190	Shared Neighborhood Hits	13
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

MLL2_HUMAN
NC score	0.030698 (rank : 104)	θ value	0.21417 (rank : 70)
Query Neighborhood Hits	216	Target Neighborhood Hits	1788	Shared Neighborhood Hits	69
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FIP1_MOUSE
NC score	0.029899 (rank : 105)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	216	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

3BP2_MOUSE
NC score	0.029874 (rank : 106)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	216	Target Neighborhood Hits	142	Shared Neighborhood Hits	19
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ICAL_MOUSE
NC score	0.029820 (rank : 107)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	216	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

TEX2_HUMAN
NC score	0.029514 (rank : 108)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	216	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

WBS14_HUMAN
NC score	0.028956 (rank : 109)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	216	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

MAGE1_HUMAN
NC score	0.028067 (rank : 110)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	216	Target Neighborhood Hits	1389	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP4_MOUSE
NC score	0.026194 (rank : 111)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	216	Target Neighborhood Hits	409	Shared Neighborhood Hits	33
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TOPB1_MOUSE
NC score	0.025847 (rank : 112)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	216	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

ALEX_MOUSE
NC score	0.025260 (rank : 113)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	216	Target Neighborhood Hits	197	Shared Neighborhood Hits	23
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

RCOR3_HUMAN
NC score	0.024922 (rank : 114)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	216	Target Neighborhood Hits	161	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

NCOR2_HUMAN
NC score	0.024669 (rank : 115)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	216	Target Neighborhood Hits	870	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SPRR3_MOUSE
NC score	0.024520 (rank : 116)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	216	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

RCOR3_MOUSE
NC score	0.024184 (rank : 117)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	216	Target Neighborhood Hits	110	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

MILK1_MOUSE
NC score	0.023970 (rank : 118)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	216	Target Neighborhood Hits	788	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PCQAP_MOUSE
NC score	0.023756 (rank : 119)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	216	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

SEPT9_HUMAN
NC score	0.023591 (rank : 120)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	216	Target Neighborhood Hits	706	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

MYCB2_MOUSE
NC score	0.023095 (rank : 121)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	216	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TACC3_HUMAN
NC score	0.023067 (rank : 122)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	216	Target Neighborhood Hits	779	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CO039_MOUSE
NC score	0.022750 (rank : 123)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	216	Target Neighborhood Hits	445	Shared Neighborhood Hits	39
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

ARI1B_HUMAN
NC score	0.022161 (rank : 124)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	216	Target Neighborhood Hits	567	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

SON_MOUSE
NC score	0.021099 (rank : 125)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	216	Target Neighborhood Hits	957	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SGIP1_HUMAN
NC score	0.019590 (rank : 126)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	216	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

IF35_MOUSE
NC score	0.018846 (rank : 127)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	216	Target Neighborhood Hits	210	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

TCF20_HUMAN
NC score	0.018784 (rank : 128)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	216	Target Neighborhood Hits	323	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

DDIT3_HUMAN
NC score	0.018579 (rank : 129)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	216	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

TARA_HUMAN
NC score	0.018554 (rank : 130)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	216	Target Neighborhood Hits	1626	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PHC1_MOUSE
NC score	0.018444 (rank : 131)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	216	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	Q64028, P70359, Q64307, Q8BZ80	Gene names	Phc1, Edr, Edr1, Rae28
Domain Architecture
Description	Polyhomeotic-like protein 1 (mPH1) (Early development regulatory protein 1) (RAE-28).

APS_MOUSE
NC score	0.017917 (rank : 132)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	216	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

MNT_HUMAN
NC score	0.017747 (rank : 133)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	216	Target Neighborhood Hits	496	Shared Neighborhood Hits	33
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NFRKB_HUMAN
NC score	0.017132 (rank : 134)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	216	Target Neighborhood Hits	211	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ODO2_MOUSE
NC score	0.016640 (rank : 135)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	216	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

PRGC2_MOUSE
NC score	0.016414 (rank : 136)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	216	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

MINT_HUMAN
NC score	0.016263 (rank : 137)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	216	Target Neighborhood Hits	1291	Shared Neighborhood Hits	48
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

HUWE1_HUMAN
NC score	0.016138 (rank : 138)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	216	Target Neighborhood Hits	443	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

DAAM2_MOUSE
NC score	0.015962 (rank : 139)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	216	Target Neighborhood Hits	371	Shared Neighborhood Hits	12
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

INP5E_HUMAN
NC score	0.015850 (rank : 140)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	216	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

REPS2_HUMAN
NC score	0.015712 (rank : 141)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	216	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

MMTA2_HUMAN
NC score	0.015249 (rank : 142)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	216	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BU76, Q6P5Y0, Q6ZTZ6, Q6ZWA6, Q8IZH3	Gene names	MMTAG2, C1orf35
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 (hMMTAG2).

DMN_HUMAN
NC score	0.015082 (rank : 143)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	216	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

TSSC4_HUMAN
NC score	0.014791 (rank : 144)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	216	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5U2, Q86VL2, Q9BRS6	Gene names	TSSC4
Domain Architecture	No domain graphic available
Description	Protein TSSC4 (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) (Tumor-suppressing STF cDNA 4 protein).

DTX1_MOUSE
NC score	0.014583 (rank : 145)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	216	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

SSH1_MOUSE
NC score	0.014464 (rank : 146)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	216	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

SOX13_MOUSE
NC score	0.014025 (rank : 147)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	216	Target Neighborhood Hits	495	Shared Neighborhood Hits	31
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

ADDA_MOUSE
NC score	0.013951 (rank : 148)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	216	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

RBBP6_MOUSE
NC score	0.013738 (rank : 149)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	216	Target Neighborhood Hits	1014	Shared Neighborhood Hits	32
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

A20A2_HUMAN
NC score	0.013446 (rank : 150)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	216	Target Neighborhood Hits	716	Shared Neighborhood Hits	15
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

SYN2_HUMAN
NC score	0.013385 (rank : 151)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	216	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TTLL4_HUMAN
NC score	0.013142 (rank : 152)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	216	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

ALKB5_HUMAN
NC score	0.012692 (rank : 153)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	216	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P6C2, Q9NXD6	Gene names	ALKBH5
Domain Architecture	No domain graphic available
Description	Alkylated repair protein alkB homolog 5.

GNDS_HUMAN
NC score	0.012689 (rank : 154)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	216	Target Neighborhood Hits	201	Shared Neighborhood Hits	22
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

PLCB2_HUMAN
NC score	0.012677 (rank : 155)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	216	Target Neighborhood Hits	608	Shared Neighborhood Hits	12
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

HPS4_MOUSE
NC score	0.012649 (rank : 156)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	216	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

A20A3_HUMAN
NC score	0.012622 (rank : 157)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	216	Target Neighborhood Hits	692	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A1_HUMAN
NC score	0.012617 (rank : 158)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	216	Target Neighborhood Hits	698	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

PGCA_HUMAN
NC score	0.012468 (rank : 159)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	216	Target Neighborhood Hits	821	Shared Neighborhood Hits	29
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

A20A4_HUMAN
NC score	0.012428 (rank : 160)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	216	Target Neighborhood Hits	710	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

NR6A1_MOUSE
NC score	0.012234 (rank : 161)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	216	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

CUTL1_MOUSE
NC score	0.012070 (rank : 162)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	216	Target Neighborhood Hits	1620	Shared Neighborhood Hits	58
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ARHG1_HUMAN
NC score	0.011823 (rank : 163)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	216	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

DAAM2_HUMAN
NC score	0.011740 (rank : 164)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	216	Target Neighborhood Hits	350	Shared Neighborhood Hits	9
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

K0141_HUMAN
NC score	0.011584 (rank : 165)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	216	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q14154, Q969R4, Q96EU9	Gene names	KIAA0141
Domain Architecture
Description	Protein KIAA0141.

ANR35_HUMAN
NC score	0.011555 (rank : 166)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	216	Target Neighborhood Hits	784	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

E2F4_HUMAN
NC score	0.011149 (rank : 167)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	216	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

P2RX2_HUMAN
NC score	0.011054 (rank : 168)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	216	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

NR6A1_HUMAN
NC score	0.010835 (rank : 169)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	216	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

EP400_HUMAN
NC score	0.009510 (rank : 170)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	216	Target Neighborhood Hits	556	Shared Neighborhood Hits	30
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FOG1_HUMAN
NC score	0.009371 (rank : 171)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	216	Target Neighborhood Hits	981	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CT075_MOUSE
NC score	0.009228 (rank : 172)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	216	Target Neighborhood Hits	358	Shared Neighborhood Hits	11
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

ES8L1_HUMAN
NC score	0.008842 (rank : 173)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	216	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

RU17_MOUSE
NC score	0.008803 (rank : 174)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	216	Target Neighborhood Hits	278	Shared Neighborhood Hits	8
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

UBP36_HUMAN
NC score	0.008410 (rank : 175)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	216	Target Neighborhood Hits	232	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

MAGD2_HUMAN
NC score	0.008176 (rank : 176)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	216	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UNF1, O76058, Q5BJF3, Q8NAL6, Q9H218, Q9P0U9, Q9UM52	Gene names	MAGED2, BCG1
Domain Architecture
Description	Melanoma-associated antigen D2 (MAGE-D2 antigen) (MAGE-D) (Breast cancer-associated gene 1 protein) (BCG-1) (11B6) (Hepatocellular carcinoma-associated protein JCL-1).

TSH3_HUMAN
NC score	0.008009 (rank : 177)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	216	Target Neighborhood Hits	564	Shared Neighborhood Hits	15
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

TLE3_HUMAN
NC score	0.007396 (rank : 178)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	216	Target Neighborhood Hits	385	Shared Neighborhood Hits	13
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

CCDC7_HUMAN
NC score	0.007354 (rank : 179)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	216	Target Neighborhood Hits	253	Shared Neighborhood Hits	6
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

TLE3_MOUSE
NC score	0.007140 (rank : 180)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	216	Target Neighborhood Hits	378	Shared Neighborhood Hits	9
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

FOXC2_HUMAN
NC score	0.007137 (rank : 181)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	216	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

TIF1G_MOUSE
NC score	0.007119 (rank : 182)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	216	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

CAC1H_HUMAN
NC score	0.007011 (rank : 183)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	216	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

ANR38_MOUSE
NC score	0.006626 (rank : 184)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	216	Target Neighborhood Hits	512	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CATZ_HUMAN
NC score	0.006500 (rank : 185)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	216	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBR2, O75331, Q9UQV5, Q9UQV6	Gene names	CTSZ
Domain Architecture
Description	Cathepsin Z precursor (EC 3.4.22.-) (Cathepsin X) (Cathepsin P).

TTBK2_HUMAN
NC score	0.006247 (rank : 186)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	216	Target Neighborhood Hits	822	Shared Neighborhood Hits	18
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

TTBK2_MOUSE
NC score	0.006108 (rank : 187)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	216	Target Neighborhood Hits	811	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

RU17_HUMAN
NC score	0.005981 (rank : 188)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	216	Target Neighborhood Hits	280	Shared Neighborhood Hits	7
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

PHF12_HUMAN
NC score	0.005939 (rank : 189)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	216	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

FREM3_HUMAN
NC score	0.005893 (rank : 190)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	216	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

TBX3_MOUSE
NC score	0.005726 (rank : 191)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	216	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TF65_MOUSE
NC score	0.005673 (rank : 192)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	216	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

OLIG1_HUMAN
NC score	0.005374 (rank : 193)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	216	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

NR1H2_HUMAN
NC score	0.005360 (rank : 194)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	216	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

FOXI1_HUMAN
NC score	0.005005 (rank : 195)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	216	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q12951, Q14518, Q66SR7, Q8N6L8	Gene names	FOXI1, FKHL10, FREAC6
Domain Architecture
Description	Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead- related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HNF-3/fork-head homolog 3) (HFH-3).

RREB1_HUMAN
NC score	0.004882 (rank : 196)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	216	Target Neighborhood Hits	879	Shared Neighborhood Hits	32
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

FOXB1_MOUSE
NC score	0.004751 (rank : 197)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	216	Target Neighborhood Hits	125	Shared Neighborhood Hits	7
SwissProt Accessions	Q64732, O08753	Gene names	Foxb1, Fkh5, Foxb1a, Foxb1b, Mf3
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

FOXB1_HUMAN
NC score	0.004692 (rank : 198)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	216	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q99853, O60652, O75917	Gene names	FOXB1, FKH5
Domain Architecture
Description	Forkhead box protein B1 (Transcription factor FKH-5).

ZN447_HUMAN
NC score	0.004541 (rank : 199)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	216	Target Neighborhood Hits	899	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

KCNQ1_MOUSE
NC score	0.004492 (rank : 200)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	216	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

INCE_HUMAN
NC score	0.004440 (rank : 201)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	216	Target Neighborhood Hits	978	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

ETV6_HUMAN
NC score	0.004213 (rank : 202)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	216	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

41_MOUSE
NC score	0.004206 (rank : 203)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	216	Target Neighborhood Hits	184	Shared Neighborhood Hits	9
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

BRWD1_MOUSE
NC score	0.003356 (rank : 204)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	216	Target Neighborhood Hits	478	Shared Neighborhood Hits	14
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

ANR12_HUMAN
NC score	0.003266 (rank : 205)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	216	Target Neighborhood Hits	1081	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

KCNA5_MOUSE
NC score	0.003034 (rank : 206)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	216	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

ATBF1_MOUSE
NC score	0.002961 (rank : 207)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	216	Target Neighborhood Hits	1841	Shared Neighborhood Hits	48
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PRDM2_HUMAN
NC score	0.002811 (rank : 208)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	216	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

CAN3_MOUSE
NC score	0.002439 (rank : 209)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	216	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

LRC24_MOUSE
NC score	0.001587 (rank : 210)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	216	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

CELR3_HUMAN
NC score	0.001422 (rank : 211)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	216	Target Neighborhood Hits	680	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

OTP_MOUSE
NC score	0.000840 (rank : 212)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	216	Target Neighborhood Hits	387	Shared Neighborhood Hits	8
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

SLIK1_HUMAN
NC score	0.000525 (rank : 213)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	216	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

ULK1_HUMAN
NC score	-0.000659 (rank : 214)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	216	Target Neighborhood Hits	1121	Shared Neighborhood Hits	31
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

DUET_HUMAN
NC score	-0.001221 (rank : 215)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	216	Target Neighborhood Hits	1220	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

WNK1_HUMAN
NC score	-0.001289 (rank : 216)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	216	Target Neighborhood Hits	1158	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

DYR1B_HUMAN
NC score	-0.002345 (rank : 217)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	216	Target Neighborhood Hits	831	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y463, O75258, O75788, O75789	Gene names	DYRK1B, MIRK
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Mirk protein kinase) (Minibrain-related kinase).

IRAK1_MOUSE
NC score	-0.002874 (rank : 218)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	216	Target Neighborhood Hits	784	Shared Neighborhood Hits	14
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

TIEG3_MOUSE
NC score	-0.002972 (rank : 219)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	216	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

NEK3_MOUSE
NC score	-0.002988 (rank : 220)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	216	Target Neighborhood Hits	854	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

PKN3_MOUSE
NC score	-0.004557 (rank : 221)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	216	Target Neighborhood Hits	1009	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

ZNF79_HUMAN
NC score	-0.005428 (rank : 222)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	216	Target Neighborhood Hits	761	Shared Neighborhood Hits	9
SwissProt Accessions	Q15937, Q5VVW1, Q96NV1	Gene names	ZNF79
Domain Architecture	No domain graphic available
Description	Zinc finger protein 79 (ZNFpT7).