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Network neighborhood for query Sequence : PCTL_MOUSE

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PCTL_MOUSE
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PCTL_MOUSE
θ value	1.01709e-152 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
θ value	1.51984e-148 (rank : 2)	NC score	0.999416 (rank : 2)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PPCT_MOUSE
θ value	1.16975e-15 (rank : 3)	NC score	0.628278 (rank : 3)
Query Neighborhood Hits	26	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	P53808, Q9QZX0, Q9R058	Gene names	Pctp, Stard2
Domain Architecture
Description	Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid transfer protein 2) (StARD2) (START domain-containing protein 2).

PPCT_HUMAN
θ value	1.58096e-12 (rank : 4)	NC score	0.598138 (rank : 4)
Query Neighborhood Hits	26	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKL6, Q9UIT3, Q9UKW7	Gene names	PCTP, STARD2
Domain Architecture
Description	Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid transfer protein 2) (StARD2) (START domain-containing protein 2).

RHG07_HUMAN
θ value	1.06045e-08 (rank : 5)	NC score	0.326380 (rank : 8)
Query Neighborhood Hits	26	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

ACO12_MOUSE
θ value	4.45536e-07 (rank : 6)	NC score	0.259514 (rank : 15)
Query Neighborhood Hits	26	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBK0, Q544M5, Q8R108	Gene names	Acot12, Cach, Cach1
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (mCACH-1).

RHG07_MOUSE
θ value	5.81887e-07 (rank : 7)	NC score	0.312468 (rank : 12)
Query Neighborhood Hits	26	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

STAR7_MOUSE
θ value	9.92553e-07 (rank : 8)	NC score	0.491991 (rank : 6)
Query Neighborhood Hits	26	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R1R3	Gene names	Stard7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7).

STAR7_HUMAN
θ value	1.29631e-06 (rank : 9)	NC score	0.495928 (rank : 5)
Query Neighborhood Hits	26	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQZ5, Q6GU43, Q969M6	Gene names	STARD7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7) (Protein GTT1).

STA13_HUMAN
θ value	4.92598e-06 (rank : 10)	NC score	0.326276 (rank : 9)
Query Neighborhood Hits	26	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
θ value	4.92598e-06 (rank : 11)	NC score	0.327588 (rank : 7)
Query Neighborhood Hits	26	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

C43BP_MOUSE
θ value	3.19293e-05 (rank : 12)	NC score	0.263241 (rank : 13)
Query Neighborhood Hits	26	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

STAR8_MOUSE
θ value	3.19293e-05 (rank : 13)	NC score	0.317585 (rank : 10)
Query Neighborhood Hits	26	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
θ value	4.1701e-05 (rank : 14)	NC score	0.314254 (rank : 11)
Query Neighborhood Hits	26	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

ACO12_HUMAN
θ value	7.1131e-05 (rank : 15)	NC score	0.227939 (rank : 16)
Query Neighborhood Hits	26	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WYK0	Gene names	ACOT12, CACH, CACH1, STARD12
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 12) (StARD12).

C43BP_HUMAN
θ value	7.1131e-05 (rank : 16)	NC score	0.260496 (rank : 14)
Query Neighborhood Hits	26	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

STAR3_HUMAN
θ value	0.00509761 (rank : 17)	NC score	0.153642 (rank : 20)
Query Neighborhood Hits	26	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q14849, Q53Y53, Q96HM9	Gene names	STARD3, CAB1, MLN64
Domain Architecture
Description	StAR-related lipid transfer protein 3 (StARD3) (START domain- containing protein 3) (Metastatic lymph node protein 64) (Protein MLN 64) (Protein CAB1).

STAR6_MOUSE
θ value	0.00509761 (rank : 18)	NC score	0.192173 (rank : 19)
Query Neighborhood Hits	26	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	P59096	Gene names	Stard6
Domain Architecture
Description	StAR-related lipid transfer protein 6 (StARD6) (START domain- containing protein 6).

STAR_MOUSE
θ value	0.0193708 (rank : 19)	NC score	0.195803 (rank : 18)
Query Neighborhood Hits	26	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P51557, Q543A5, Q924Y5, Q9D2G1	Gene names	Star
Domain Architecture
Description	Steroidogenic acute regulatory protein, mitochondrial precursor (StAR) (StARD1) (Luteinizing hormone-induced protein).

STAR_HUMAN
θ value	0.0330416 (rank : 20)	NC score	0.195988 (rank : 17)
Query Neighborhood Hits	26	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P49675, Q16396	Gene names	STAR
Domain Architecture
Description	Steroidogenic acute regulatory protein, mitochondrial precursor (StAR) (StARD1).

STAR6_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.149909 (rank : 21)
Query Neighborhood Hits	26	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P59095	Gene names	STARD6
Domain Architecture
Description	StAR-related lipid transfer protein 6 (StARD6) (START domain- containing protein 6).

MKL1_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.025058 (rank : 72)
Query Neighborhood Hits	26	Target Neighborhood Hits	232	Shared Neighborhood Hits	3
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

PA24F_MOUSE
θ value	6.88961 (rank : 23)	NC score	0.009066 (rank : 74)
Query Neighborhood Hits	26	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

SIDT2_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.012963 (rank : 73)
Query Neighborhood Hits	26	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NBJ9, Q8NBY7, Q9Y357	Gene names	SIDT2
Domain Architecture	No domain graphic available
Description	SID1 transmembrane family member 2 precursor.

SNX24_HUMAN
θ value	8.99809 (rank : 25)	NC score	0.028879 (rank : 70)
Query Neighborhood Hits	26	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y343, Q6UY33	Gene names	SNX24
Domain Architecture
Description	Sorting nexin-24.

SNX24_MOUSE
θ value	8.99809 (rank : 26)	NC score	0.028797 (rank : 71)
Query Neighborhood Hits	26	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CRB0	Gene names	Snx24
Domain Architecture	No domain graphic available
Description	Sorting nexin-24.

3BP1_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.075273 (rank : 30)
Query Neighborhood Hits	26	Target Neighborhood Hits	376	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
θ value	θ > 10 (rank : 28)	NC score	0.076347 (rank : 29)
Query Neighborhood Hits	26	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ABR_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.058188 (rank : 46)
Query Neighborhood Hits	26	Target Neighborhood Hits	166	Shared Neighborhood Hits	7
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ACO11_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.120540 (rank : 22)
Query Neighborhood Hits	26	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXI4, O75187, Q96DI1, Q9H883	Gene names	ACOT11, BFIT, KIAA0707, THEA
Domain Architecture
Description	Acyl-coenzyme A thioesterase 11 (EC 3.1.2.-) (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Brown fat-inducible thioesterase) (BFIT) (Adipose-associated thioesterase).

ACO11_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.113151 (rank : 23)
Query Neighborhood Hits	26	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHQ9	Gene names	Acot11, Bfit, Thea
Domain Architecture
Description	Acyl-coenzyme A thioesterase 11 (EC 3.1.2.-) (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Brown fat-inducible thioesterase) (BFIT) (Adipose-associated thioesterase).

BACH_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.051929 (rank : 61)
Query Neighborhood Hits	26	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

BACH_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.051453 (rank : 63)
Query Neighborhood Hits	26	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V12, Q59HQ2	Gene names	Acot7, Bach
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

BCR_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.055798 (rank : 51)
Query Neighborhood Hits	26	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CE005_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.057203 (rank : 49)
Query Neighborhood Hits	26	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.057466 (rank : 47)
Query Neighborhood Hits	26	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CEND2_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.052776 (rank : 58)
Query Neighborhood Hits	26	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.050554 (rank : 67)
Query Neighborhood Hits	26	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.052870 (rank : 57)
Query Neighborhood Hits	26	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CHIO_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.050217 (rank : 68)
Query Neighborhood Hits	26	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

FNBP2_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.053318 (rank : 56)
Query Neighborhood Hits	26	Target Neighborhood Hits	432	Shared Neighborhood Hits	6
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GMIP_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.059833 (rank : 45)
Query Neighborhood Hits	26	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.060539 (rank : 44)
Query Neighborhood Hits	26	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GRLF1_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.068436 (rank : 34)
Query Neighborhood Hits	26	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

OPHN1_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.051085 (rank : 66)
Query Neighborhood Hits	26	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.052742 (rank : 59)
Query Neighborhood Hits	26	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RBP1_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.067806 (rank : 35)
Query Neighborhood Hits	26	Target Neighborhood Hits	521	Shared Neighborhood Hits	6
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.072047 (rank : 33)
Query Neighborhood Hits	26	Target Neighborhood Hits	493	Shared Neighborhood Hits	6
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.054394 (rank : 54)
Query Neighborhood Hits	26	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG01_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.067325 (rank : 37)
Query Neighborhood Hits	26	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG04_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.064912 (rank : 39)
Query Neighborhood Hits	26	Target Neighborhood Hits	307	Shared Neighborhood Hits	6
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG06_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.083138 (rank : 28)
Query Neighborhood Hits	26	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.084402 (rank : 27)
Query Neighborhood Hits	26	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG08_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.051919 (rank : 62)
Query Neighborhood Hits	26	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.055416 (rank : 52)
Query Neighborhood Hits	26	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG09_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.054782 (rank : 53)
Query Neighborhood Hits	26	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.061935 (rank : 41)
Query Neighborhood Hits	26	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.061082 (rank : 42)
Query Neighborhood Hits	26	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG18_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.094861 (rank : 25)
Query Neighborhood Hits	26	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.100455 (rank : 24)
Query Neighborhood Hits	26	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG25_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.050022 (rank : 69)
Query Neighborhood Hits	26	Target Neighborhood Hits	550	Shared Neighborhood Hits	8
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.051244 (rank : 65)
Query Neighborhood Hits	26	Target Neighborhood Hits	492	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG26_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.052631 (rank : 60)
Query Neighborhood Hits	26	Target Neighborhood Hits	281	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SRGP1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.051331 (rank : 64)
Query Neighborhood Hits	26	Target Neighborhood Hits	390	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.055978 (rank : 50)
Query Neighborhood Hits	26	Target Neighborhood Hits	331	Shared Neighborhood Hits	6
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.053735 (rank : 55)
Query Neighborhood Hits	26	Target Neighborhood Hits	324	Shared Neighborhood Hits	6
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

STAR3_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.086060 (rank : 26)
Query Neighborhood Hits	26	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q61542	Gene names	Stard3, Es64, Mln64
Domain Architecture
Description	StAR-related lipid transfer protein 3 (StARD3) (START domain- containing protein 3) (Protein MLN 64) (Protein ES 64).

STAR4_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.066068 (rank : 38)
Query Neighborhood Hits	26	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q96DR4	Gene names	STARD4
Domain Architecture
Description	StAR-related lipid transfer protein 4 (StARD4) (START domain- containing protein 4).

STAR4_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.074418 (rank : 31)
Query Neighborhood Hits	26	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q99JV5	Gene names	Stard4
Domain Architecture
Description	StAR-related lipid transfer protein 4 (StARD4) (START domain- containing protein 4).

STAR5_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.067557 (rank : 36)
Query Neighborhood Hits	26	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NSY2, P59094	Gene names	STARD5
Domain Architecture
Description	StAR-related lipid transfer protein 5 (StARD5) (START domain- containing protein 5).

STAR5_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.072586 (rank : 32)
Query Neighborhood Hits	26	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EPQ7, Q9CQY0, Q9EPQ6	Gene names	Stard5
Domain Architecture
Description	StAR-related lipid transfer protein 5 (StARD5) (START domain- containing protein 5).

TAGAP_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.064063 (rank : 40)
Query Neighborhood Hits	26	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.060743 (rank : 43)
Query Neighborhood Hits	26	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TCGAP_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.057254 (rank : 48)
Query Neighborhood Hits	26	Target Neighborhood Hits	409	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

Hits sorted by NC score

PCTL_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.01709e-152 (rank : 1)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.999416 (rank : 2)	θ value	1.51984e-148 (rank : 2)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PPCT_MOUSE
NC score	0.628278 (rank : 3)	θ value	1.16975e-15 (rank : 3)
Query Neighborhood Hits	26	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	P53808, Q9QZX0, Q9R058	Gene names	Pctp, Stard2
Domain Architecture
Description	Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid transfer protein 2) (StARD2) (START domain-containing protein 2).

PPCT_HUMAN
NC score	0.598138 (rank : 4)	θ value	1.58096e-12 (rank : 4)
Query Neighborhood Hits	26	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKL6, Q9UIT3, Q9UKW7	Gene names	PCTP, STARD2
Domain Architecture
Description	Phosphatidylcholine transfer protein (PC-TP) (StAR-related lipid transfer protein 2) (StARD2) (START domain-containing protein 2).

STAR7_HUMAN
NC score	0.495928 (rank : 5)	θ value	1.29631e-06 (rank : 9)
Query Neighborhood Hits	26	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQZ5, Q6GU43, Q969M6	Gene names	STARD7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7) (Protein GTT1).

STAR7_MOUSE
NC score	0.491991 (rank : 6)	θ value	9.92553e-07 (rank : 8)
Query Neighborhood Hits	26	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R1R3	Gene names	Stard7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7).

STA13_MOUSE
NC score	0.327588 (rank : 7)	θ value	4.92598e-06 (rank : 11)
Query Neighborhood Hits	26	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

RHG07_HUMAN
NC score	0.326380 (rank : 8)	θ value	1.06045e-08 (rank : 5)
Query Neighborhood Hits	26	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

STA13_HUMAN
NC score	0.326276 (rank : 9)	θ value	4.92598e-06 (rank : 10)
Query Neighborhood Hits	26	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STAR8_MOUSE
NC score	0.317585 (rank : 10)	θ value	3.19293e-05 (rank : 13)
Query Neighborhood Hits	26	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.314254 (rank : 11)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	26	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG07_MOUSE
NC score	0.312468 (rank : 12)	θ value	5.81887e-07 (rank : 7)
Query Neighborhood Hits	26	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

C43BP_MOUSE
NC score	0.263241 (rank : 13)	θ value	3.19293e-05 (rank : 12)
Query Neighborhood Hits	26	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_HUMAN
NC score	0.260496 (rank : 14)	θ value	7.1131e-05 (rank : 16)
Query Neighborhood Hits	26	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

ACO12_MOUSE
NC score	0.259514 (rank : 15)	θ value	4.45536e-07 (rank : 6)
Query Neighborhood Hits	26	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBK0, Q544M5, Q8R108	Gene names	Acot12, Cach, Cach1
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (mCACH-1).

ACO12_HUMAN
NC score	0.227939 (rank : 16)	θ value	7.1131e-05 (rank : 15)
Query Neighborhood Hits	26	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WYK0	Gene names	ACOT12, CACH, CACH1, STARD12
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 12) (StARD12).

STAR_HUMAN
NC score	0.195988 (rank : 17)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	26	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P49675, Q16396	Gene names	STAR
Domain Architecture
Description	Steroidogenic acute regulatory protein, mitochondrial precursor (StAR) (StARD1).

STAR_MOUSE
NC score	0.195803 (rank : 18)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	26	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P51557, Q543A5, Q924Y5, Q9D2G1	Gene names	Star
Domain Architecture
Description	Steroidogenic acute regulatory protein, mitochondrial precursor (StAR) (StARD1) (Luteinizing hormone-induced protein).

STAR6_MOUSE
NC score	0.192173 (rank : 19)	θ value	0.00509761 (rank : 18)
Query Neighborhood Hits	26	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	P59096	Gene names	Stard6
Domain Architecture
Description	StAR-related lipid transfer protein 6 (StARD6) (START domain- containing protein 6).

STAR3_HUMAN
NC score	0.153642 (rank : 20)	θ value	0.00509761 (rank : 17)
Query Neighborhood Hits	26	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	Q14849, Q53Y53, Q96HM9	Gene names	STARD3, CAB1, MLN64
Domain Architecture
Description	StAR-related lipid transfer protein 3 (StARD3) (START domain- containing protein 3) (Metastatic lymph node protein 64) (Protein MLN 64) (Protein CAB1).

STAR6_HUMAN
NC score	0.149909 (rank : 21)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	26	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P59095	Gene names	STARD6
Domain Architecture
Description	StAR-related lipid transfer protein 6 (StARD6) (START domain- containing protein 6).

ACO11_HUMAN
NC score	0.120540 (rank : 22)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	26	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXI4, O75187, Q96DI1, Q9H883	Gene names	ACOT11, BFIT, KIAA0707, THEA
Domain Architecture
Description	Acyl-coenzyme A thioesterase 11 (EC 3.1.2.-) (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Brown fat-inducible thioesterase) (BFIT) (Adipose-associated thioesterase).

ACO11_MOUSE
NC score	0.113151 (rank : 23)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	26	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHQ9	Gene names	Acot11, Bfit, Thea
Domain Architecture
Description	Acyl-coenzyme A thioesterase 11 (EC 3.1.2.-) (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Brown fat-inducible thioesterase) (BFIT) (Adipose-associated thioesterase).

RHG18_MOUSE
NC score	0.100455 (rank : 24)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	26	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG18_HUMAN
NC score	0.094861 (rank : 25)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	26	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

STAR3_MOUSE
NC score	0.086060 (rank : 26)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	26	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q61542	Gene names	Stard3, Es64, Mln64
Domain Architecture
Description	StAR-related lipid transfer protein 3 (StARD3) (START domain- containing protein 3) (Protein MLN 64) (Protein ES 64).

RHG06_MOUSE
NC score	0.084402 (rank : 27)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	26	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_HUMAN
NC score	0.083138 (rank : 28)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	26	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_MOUSE
NC score	0.076347 (rank : 29)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	26	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_HUMAN
NC score	0.075273 (rank : 30)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	26	Target Neighborhood Hits	376	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

STAR4_MOUSE
NC score	0.074418 (rank : 31)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	26	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q99JV5	Gene names	Stard4
Domain Architecture
Description	StAR-related lipid transfer protein 4 (StARD4) (START domain- containing protein 4).

STAR5_MOUSE
NC score	0.072586 (rank : 32)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	26	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EPQ7, Q9CQY0, Q9EPQ6	Gene names	Stard5
Domain Architecture
Description	StAR-related lipid transfer protein 5 (StARD5) (START domain- containing protein 5).

RBP1_MOUSE
NC score	0.072047 (rank : 33)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	26	Target Neighborhood Hits	493	Shared Neighborhood Hits	6
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

GRLF1_HUMAN
NC score	0.068436 (rank : 34)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	26	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RBP1_HUMAN
NC score	0.067806 (rank : 35)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	26	Target Neighborhood Hits	521	Shared Neighborhood Hits	6
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

STAR5_HUMAN
NC score	0.067557 (rank : 36)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	26	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NSY2, P59094	Gene names	STARD5
Domain Architecture
Description	StAR-related lipid transfer protein 5 (StARD5) (START domain- containing protein 5).

RHG01_HUMAN
NC score	0.067325 (rank : 37)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	26	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

STAR4_HUMAN
NC score	0.066068 (rank : 38)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	26	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q96DR4	Gene names	STARD4
Domain Architecture
Description	StAR-related lipid transfer protein 4 (StARD4) (START domain- containing protein 4).

RHG04_HUMAN
NC score	0.064912 (rank : 39)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	26	Target Neighborhood Hits	307	Shared Neighborhood Hits	6
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

TAGAP_HUMAN
NC score	0.064063 (rank : 40)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	26	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG12_HUMAN
NC score	0.061935 (rank : 41)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	26	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.061082 (rank : 42)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	26	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

TAGAP_MOUSE
NC score	0.060743 (rank : 43)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	26	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

GMIP_MOUSE
NC score	0.060539 (rank : 44)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	26	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.059833 (rank : 45)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	26	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

ABR_HUMAN
NC score	0.058188 (rank : 46)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	26	Target Neighborhood Hits	166	Shared Neighborhood Hits	7
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

CE005_MOUSE
NC score	0.057466 (rank : 47)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	26	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

TCGAP_MOUSE
NC score	0.057254 (rank : 48)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	26	Target Neighborhood Hits	409	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CE005_HUMAN
NC score	0.057203 (rank : 49)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	26	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

SRGP2_HUMAN
NC score	0.055978 (rank : 50)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	26	Target Neighborhood Hits	331	Shared Neighborhood Hits	6
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

BCR_HUMAN
NC score	0.055798 (rank : 51)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	26	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG08_MOUSE
NC score	0.055416 (rank : 52)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	26	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG09_HUMAN
NC score	0.054782 (rank : 53)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	26	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RGAP1_HUMAN
NC score	0.054394 (rank : 54)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	26	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

SRGP2_MOUSE
NC score	0.053735 (rank : 55)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	26	Target Neighborhood Hits	324	Shared Neighborhood Hits	6
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

FNBP2_HUMAN
NC score	0.053318 (rank : 56)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	26	Target Neighborhood Hits	432	Shared Neighborhood Hits	6
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

CEND3_MOUSE
NC score	0.052870 (rank : 57)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	26	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND2_HUMAN
NC score	0.052776 (rank : 58)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	26	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

OPHN1_MOUSE
NC score	0.052742 (rank : 59)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	26	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG26_HUMAN
NC score	0.052631 (rank : 60)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	26	Target Neighborhood Hits	281	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

BACH_HUMAN
NC score	0.051929 (rank : 61)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	26	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

RHG08_HUMAN
NC score	0.051919 (rank : 62)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	26	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

BACH_MOUSE
NC score	0.051453 (rank : 63)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	26	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V12, Q59HQ2	Gene names	Acot7, Bach
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

SRGP1_HUMAN
NC score	0.051331 (rank : 64)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	26	Target Neighborhood Hits	390	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RHG25_MOUSE
NC score	0.051244 (rank : 65)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	26	Target Neighborhood Hits	492	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

OPHN1_HUMAN
NC score	0.051085 (rank : 66)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	26	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

CEND3_HUMAN
NC score	0.050554 (rank : 67)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	26	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CHIO_MOUSE
NC score	0.050217 (rank : 68)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	26	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG25_HUMAN
NC score	0.050022 (rank : 69)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	26	Target Neighborhood Hits	550	Shared Neighborhood Hits	8
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SNX24_HUMAN
NC score	0.028879 (rank : 70)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	26	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y343, Q6UY33	Gene names	SNX24
Domain Architecture
Description	Sorting nexin-24.

SNX24_MOUSE
NC score	0.028797 (rank : 71)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	26	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CRB0	Gene names	Snx24
Domain Architecture	No domain graphic available
Description	Sorting nexin-24.

MKL1_HUMAN
NC score	0.025058 (rank : 72)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	26	Target Neighborhood Hits	232	Shared Neighborhood Hits	3
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

SIDT2_HUMAN
NC score	0.012963 (rank : 73)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	26	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NBJ9, Q8NBY7, Q9Y357	Gene names	SIDT2
Domain Architecture	No domain graphic available
Description	SID1 transmembrane family member 2 precursor.

PA24F_MOUSE
NC score	0.009066 (rank : 74)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	26	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).