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Network neighborhood for query Sequence : RGAP1_HUMAN

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RGAP1_HUMAN
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RGAP1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	189	Target Neighborhood Hits	189	Shared Neighborhood Hits	189
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
θ value	0 (rank : 2)	NC score	0.981980 (rank : 2)
Query Neighborhood Hits	189	Target Neighborhood Hits	185	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CHIN_MOUSE
θ value	2.42779e-29 (rank : 3)	NC score	0.790536 (rank : 7)
Query Neighborhood Hits	189	Target Neighborhood Hits	229	Shared Neighborhood Hits	97
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
θ value	1.2049e-28 (rank : 4)	NC score	0.786786 (rank : 9)
Query Neighborhood Hits	189	Target Neighborhood Hits	227	Shared Neighborhood Hits	96
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

MYO9B_HUMAN
θ value	5.59698e-26 (rank : 5)	NC score	0.465227 (rank : 58)
Query Neighborhood Hits	189	Target Neighborhood Hits	641	Shared Neighborhood Hits	114
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CHIO_MOUSE
θ value	1.24688e-25 (rank : 6)	NC score	0.814998 (rank : 3)
Query Neighborhood Hits	189	Target Neighborhood Hits	130	Shared Neighborhood Hits	95
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_HUMAN
θ value	2.77775e-25 (rank : 7)	NC score	0.783402 (rank : 11)
Query Neighborhood Hits	189	Target Neighborhood Hits	220	Shared Neighborhood Hits	96
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

MYO9B_MOUSE
θ value	3.62785e-25 (rank : 8)	NC score	0.471120 (rank : 57)
Query Neighborhood Hits	189	Target Neighborhood Hits	311	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ABR_HUMAN
θ value	7.56453e-23 (rank : 9)	NC score	0.738423 (rank : 27)
Query Neighborhood Hits	189	Target Neighborhood Hits	166	Shared Neighborhood Hits	68
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG26_HUMAN
θ value	1.09232e-21 (rank : 10)	NC score	0.740376 (rank : 26)
Query Neighborhood Hits	189	Target Neighborhood Hits	281	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

BCR_HUMAN
θ value	2.69047e-20 (rank : 11)	NC score	0.718298 (rank : 31)
Query Neighborhood Hits	189	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

OPHN1_HUMAN
θ value	1.47631e-18 (rank : 12)	NC score	0.773101 (rank : 14)
Query Neighborhood Hits	189	Target Neighborhood Hits	161	Shared Neighborhood Hits	74
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

GMIP_HUMAN
θ value	3.28887e-18 (rank : 13)	NC score	0.809889 (rank : 6)
Query Neighborhood Hits	189	Target Neighborhood Hits	225	Shared Neighborhood Hits	91
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

OPHN1_MOUSE
θ value	5.60996e-18 (rank : 14)	NC score	0.770196 (rank : 15)
Query Neighborhood Hits	189	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

GMIP_MOUSE
θ value	3.63628e-17 (rank : 15)	NC score	0.810910 (rank : 5)
Query Neighborhood Hits	189	Target Neighborhood Hits	202	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

TCGAP_HUMAN
θ value	6.20254e-17 (rank : 16)	NC score	0.669249 (rank : 38)
Query Neighborhood Hits	189	Target Neighborhood Hits	872	Shared Neighborhood Hits	68
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	6.20254e-17 (rank : 17)	NC score	0.755000 (rank : 21)
Query Neighborhood Hits	189	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG12_HUMAN
θ value	8.10077e-17 (rank : 18)	NC score	0.789096 (rank : 8)
Query Neighborhood Hits	189	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RBP1_MOUSE
θ value	1.38178e-16 (rank : 19)	NC score	0.743138 (rank : 24)
Query Neighborhood Hits	189	Target Neighborhood Hits	493	Shared Neighborhood Hits	116
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG12_MOUSE
θ value	2.35696e-16 (rank : 20)	NC score	0.785021 (rank : 10)
Query Neighborhood Hits	189	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG05_HUMAN
θ value	5.25075e-16 (rank : 21)	NC score	0.741197 (rank : 25)
Query Neighborhood Hits	189	Target Neighborhood Hits	158	Shared Neighborhood Hits	73
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RBP1_HUMAN
θ value	6.85773e-16 (rank : 22)	NC score	0.724943 (rank : 30)
Query Neighborhood Hits	189	Target Neighborhood Hits	521	Shared Neighborhood Hits	116
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG09_HUMAN
θ value	1.52774e-15 (rank : 23)	NC score	0.814131 (rank : 4)
Query Neighborhood Hits	189	Target Neighborhood Hits	186	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CEND2_HUMAN
θ value	3.40345e-15 (rank : 24)	NC score	0.636313 (rank : 45)
Query Neighborhood Hits	189	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RHG05_MOUSE
θ value	7.58209e-15 (rank : 25)	NC score	0.747640 (rank : 23)
Query Neighborhood Hits	189	Target Neighborhood Hits	165	Shared Neighborhood Hits	78
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_MOUSE
θ value	1.09485e-13 (rank : 26)	NC score	0.777077 (rank : 13)
Query Neighborhood Hits	189	Target Neighborhood Hits	105	Shared Neighborhood Hits	61
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

GRLF1_HUMAN
θ value	1.86753e-13 (rank : 27)	NC score	0.768148 (rank : 16)
Query Neighborhood Hits	189	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG06_HUMAN
θ value	1.86753e-13 (rank : 28)	NC score	0.777791 (rank : 12)
Query Neighborhood Hits	189	Target Neighborhood Hits	114	Shared Neighborhood Hits	61
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CE005_HUMAN
θ value	3.18553e-13 (rank : 29)	NC score	0.637998 (rank : 44)
Query Neighborhood Hits	189	Target Neighborhood Hits	213	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RHG25_MOUSE
θ value	3.18553e-13 (rank : 30)	NC score	0.715241 (rank : 32)
Query Neighborhood Hits	189	Target Neighborhood Hits	492	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
θ value	4.16044e-13 (rank : 31)	NC score	0.698630 (rank : 33)
Query Neighborhood Hits	189	Target Neighborhood Hits	550	Shared Neighborhood Hits	114
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CE005_MOUSE
θ value	7.09661e-13 (rank : 32)	NC score	0.635436 (rank : 46)
Query Neighborhood Hits	189	Target Neighborhood Hits	238	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

3BP1_HUMAN
θ value	9.26847e-13 (rank : 33)	NC score	0.756206 (rank : 19)
Query Neighborhood Hits	189	Target Neighborhood Hits	376	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CEND3_MOUSE
θ value	9.26847e-13 (rank : 34)	NC score	0.598448 (rank : 49)
Query Neighborhood Hits	189	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

RHG18_HUMAN
θ value	9.26847e-13 (rank : 35)	NC score	0.762627 (rank : 18)
Query Neighborhood Hits	189	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG01_HUMAN
θ value	1.2105e-12 (rank : 36)	NC score	0.751980 (rank : 22)
Query Neighborhood Hits	189	Target Neighborhood Hits	75	Shared Neighborhood Hits	61
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

CEND3_HUMAN
θ value	1.58096e-12 (rank : 37)	NC score	0.586761 (rank : 51)
Query Neighborhood Hits	189	Target Neighborhood Hits	275	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

SRGP2_HUMAN
θ value	4.59992e-12 (rank : 38)	NC score	0.671428 (rank : 37)
Query Neighborhood Hits	189	Target Neighborhood Hits	331	Shared Neighborhood Hits	84
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG04_HUMAN
θ value	1.02475e-11 (rank : 39)	NC score	0.681367 (rank : 34)
Query Neighborhood Hits	189	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG08_HUMAN
θ value	1.74796e-11 (rank : 40)	NC score	0.729703 (rank : 29)
Query Neighborhood Hits	189	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

SRGP2_MOUSE
θ value	2.28291e-11 (rank : 41)	NC score	0.663352 (rank : 39)
Query Neighborhood Hits	189	Target Neighborhood Hits	324	Shared Neighborhood Hits	86
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG18_MOUSE
θ value	3.89403e-11 (rank : 42)	NC score	0.755113 (rank : 20)
Query Neighborhood Hits	189	Target Neighborhood Hits	110	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_MOUSE
θ value	1.47974e-10 (rank : 43)	NC score	0.733985 (rank : 28)
Query Neighborhood Hits	189	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

STAR8_HUMAN
θ value	1.9326e-10 (rank : 44)	NC score	0.608755 (rank : 48)
Query Neighborhood Hits	189	Target Neighborhood Hits	216	Shared Neighborhood Hits	59
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

TAGAP_HUMAN
θ value	1.9326e-10 (rank : 45)	NC score	0.678211 (rank : 36)
Query Neighborhood Hits	189	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

SRGP1_HUMAN
θ value	2.52405e-10 (rank : 46)	NC score	0.657779 (rank : 40)
Query Neighborhood Hits	189	Target Neighborhood Hits	390	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

CEND1_MOUSE
θ value	3.29651e-10 (rank : 47)	NC score	0.544324 (rank : 54)
Query Neighborhood Hits	189	Target Neighborhood Hits	260	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

STAR8_MOUSE
θ value	1.63604e-09 (rank : 48)	NC score	0.614521 (rank : 47)
Query Neighborhood Hits	189	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND1_HUMAN
θ value	2.13673e-09 (rank : 49)	NC score	0.521429 (rank : 56)
Query Neighborhood Hits	189	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

3BP1_MOUSE
θ value	3.64472e-09 (rank : 50)	NC score	0.763676 (rank : 17)
Query Neighborhood Hits	189	Target Neighborhood Hits	238	Shared Neighborhood Hits	66
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG07_HUMAN
θ value	6.21693e-09 (rank : 51)	NC score	0.643722 (rank : 43)
Query Neighborhood Hits	189	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

FNBP2_HUMAN
θ value	2.36244e-08 (rank : 52)	NC score	0.654196 (rank : 41)
Query Neighborhood Hits	189	Target Neighborhood Hits	432	Shared Neighborhood Hits	98
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

TAGAP_MOUSE
θ value	2.36244e-08 (rank : 53)	NC score	0.678618 (rank : 35)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG07_MOUSE
θ value	3.08544e-08 (rank : 54)	NC score	0.647882 (rank : 42)
Query Neighborhood Hits	189	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

K1688_HUMAN
θ value	2.21117e-06 (rank : 55)	NC score	0.535090 (rank : 55)
Query Neighborhood Hits	189	Target Neighborhood Hits	217	Shared Neighborhood Hits	57
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K1688_MOUSE
θ value	3.77169e-06 (rank : 56)	NC score	0.546844 (rank : 53)
Query Neighborhood Hits	189	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

STA13_HUMAN
θ value	3.77169e-06 (rank : 57)	NC score	0.591726 (rank : 50)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
θ value	6.43352e-06 (rank : 58)	NC score	0.582236 (rank : 52)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

P85A_HUMAN
θ value	5.44631e-05 (rank : 59)	NC score	0.405583 (rank : 59)
Query Neighborhood Hits	189	Target Neighborhood Hits	479	Shared Neighborhood Hits	102
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	0.00035302 (rank : 60)	NC score	0.392871 (rank : 60)
Query Neighborhood Hits	189	Target Neighborhood Hits	435	Shared Neighborhood Hits	89
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
θ value	0.00390308 (rank : 61)	NC score	0.148912 (rank : 64)
Query Neighborhood Hits	189	Target Neighborhood Hits	543	Shared Neighborhood Hits	80
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CJ118_HUMAN
θ value	0.00869519 (rank : 62)	NC score	0.081856 (rank : 121)
Query Neighborhood Hits	189	Target Neighborhood Hits	937	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CTRO_HUMAN
θ value	0.0148317 (rank : 63)	NC score	0.055935 (rank : 381)
Query Neighborhood Hits	189	Target Neighborhood Hits	2092	Shared Neighborhood Hits	121
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	0.0148317 (rank : 64)	NC score	0.060229 (rank : 312)
Query Neighborhood Hits	189	Target Neighborhood Hits	2344	Shared Neighborhood Hits	124
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ANR26_MOUSE
θ value	0.0193708 (rank : 65)	NC score	0.065283 (rank : 240)
Query Neighborhood Hits	189	Target Neighborhood Hits	1554	Shared Neighborhood Hits	92
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RGNEF_MOUSE
θ value	0.0193708 (rank : 66)	NC score	0.078766 (rank : 136)
Query Neighborhood Hits	189	Target Neighborhood Hits	641	Shared Neighborhood Hits	94
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

TPM1_HUMAN
θ value	0.0330416 (rank : 67)	NC score	0.103318 (rank : 67)
Query Neighborhood Hits	189	Target Neighborhood Hits	716	Shared Neighborhood Hits	79
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	0.0330416 (rank : 68)	NC score	0.102962 (rank : 68)
Query Neighborhood Hits	189	Target Neighborhood Hits	729	Shared Neighborhood Hits	80
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

GRP3_HUMAN
θ value	0.0431538 (rank : 69)	NC score	0.158684 (rank : 63)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

TPM3_MOUSE
θ value	0.0431538 (rank : 70)	NC score	0.100515 (rank : 70)
Query Neighborhood Hits	189	Target Neighborhood Hits	676	Shared Neighborhood Hits	70
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

CROCC_HUMAN
θ value	0.0563607 (rank : 71)	NC score	0.082091 (rank : 118)
Query Neighborhood Hits	189	Target Neighborhood Hits	1409	Shared Neighborhood Hits	93
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

KPCD1_HUMAN
θ value	0.0563607 (rank : 72)	NC score	0.048190 (rank : 483)
Query Neighborhood Hits	189	Target Neighborhood Hits	901	Shared Neighborhood Hits	49
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD1_MOUSE
θ value	0.0563607 (rank : 73)	NC score	0.047897 (rank : 484)
Query Neighborhood Hits	189	Target Neighborhood Hits	891	Shared Neighborhood Hits	49
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD2_HUMAN
θ value	0.0563607 (rank : 74)	NC score	0.046523 (rank : 487)
Query Neighborhood Hits	189	Target Neighborhood Hits	910	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

KPCD3_HUMAN
θ value	0.0961366 (rank : 75)	NC score	0.048735 (rank : 482)
Query Neighborhood Hits	189	Target Neighborhood Hits	895	Shared Neighborhood Hits	49
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

KSR2_HUMAN
θ value	0.0961366 (rank : 76)	NC score	0.029325 (rank : 501)
Query Neighborhood Hits	189	Target Neighborhood Hits	920	Shared Neighborhood Hits	44
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

MRCKB_MOUSE
θ value	0.0961366 (rank : 77)	NC score	0.062673 (rank : 273)
Query Neighborhood Hits	189	Target Neighborhood Hits	2180	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

TPM3_HUMAN
θ value	0.0961366 (rank : 78)	NC score	0.098782 (rank : 72)
Query Neighborhood Hits	189	Target Neighborhood Hits	689	Shared Neighborhood Hits	70
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

CASP_MOUSE
θ value	0.163984 (rank : 79)	NC score	0.084944 (rank : 111)
Query Neighborhood Hits	189	Target Neighborhood Hits	1152	Shared Neighborhood Hits	90
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_MOUSE
θ value	0.163984 (rank : 80)	NC score	0.079835 (rank : 131)
Query Neighborhood Hits	189	Target Neighborhood Hits	1620	Shared Neighborhood Hits	93
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DGKQ_HUMAN
θ value	0.163984 (rank : 81)	NC score	0.092288 (rank : 91)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

REST_HUMAN
θ value	0.163984 (rank : 82)	NC score	0.081698 (rank : 122)
Query Neighborhood Hits	189	Target Neighborhood Hits	1605	Shared Neighborhood Hits	90
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ROCK1_HUMAN
θ value	0.163984 (rank : 83)	NC score	0.052000 (rank : 449)
Query Neighborhood Hits	189	Target Neighborhood Hits	2000	Shared Neighborhood Hits	115
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

CUTL1_HUMAN
θ value	0.21417 (rank : 84)	NC score	0.074096 (rank : 164)
Query Neighborhood Hits	189	Target Neighborhood Hits	1574	Shared Neighborhood Hits	85
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

KPCD3_MOUSE
θ value	0.21417 (rank : 85)	NC score	0.047764 (rank : 485)
Query Neighborhood Hits	189	Target Neighborhood Hits	901	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

MYH4_HUMAN
θ value	0.21417 (rank : 86)	NC score	0.096083 (rank : 78)
Query Neighborhood Hits	189	Target Neighborhood Hits	1377	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

TPM2_HUMAN
θ value	0.21417 (rank : 87)	NC score	0.097116 (rank : 75)
Query Neighborhood Hits	189	Target Neighborhood Hits	677	Shared Neighborhood Hits	76
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

CENPE_HUMAN
θ value	0.279714 (rank : 88)	NC score	0.062661 (rank : 274)
Query Neighborhood Hits	189	Target Neighborhood Hits	2060	Shared Neighborhood Hits	99
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ROCK1_MOUSE
θ value	0.279714 (rank : 89)	NC score	0.053711 (rank : 428)
Query Neighborhood Hits	189	Target Neighborhood Hits	2126	Shared Neighborhood Hits	118
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SMC2_MOUSE
θ value	0.279714 (rank : 90)	NC score	0.076963 (rank : 145)
Query Neighborhood Hits	189	Target Neighborhood Hits	1131	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

TPM2_MOUSE
θ value	0.279714 (rank : 91)	NC score	0.096734 (rank : 77)
Query Neighborhood Hits	189	Target Neighborhood Hits	676	Shared Neighborhood Hits	78
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

AMOL1_HUMAN
θ value	0.365318 (rank : 92)	NC score	0.063205 (rank : 265)
Query Neighborhood Hits	189	Target Neighborhood Hits	435	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

CROCC_MOUSE
θ value	0.365318 (rank : 93)	NC score	0.078426 (rank : 139)
Query Neighborhood Hits	189	Target Neighborhood Hits	1460	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MYH9_HUMAN
θ value	0.365318 (rank : 94)	NC score	0.093255 (rank : 89)
Query Neighborhood Hits	189	Target Neighborhood Hits	1762	Shared Neighborhood Hits	98
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RASF5_HUMAN
θ value	0.365318 (rank : 95)	NC score	0.087898 (rank : 104)
Query Neighborhood Hits	189	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

ACTN4_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.020492 (rank : 509)
Query Neighborhood Hits	189	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	0.47712 (rank : 97)	NC score	0.021179 (rank : 508)
Query Neighborhood Hits	189	Target Neighborhood Hits	276	Shared Neighborhood Hits	43
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

CYLN2_HUMAN
θ value	0.47712 (rank : 98)	NC score	0.078382 (rank : 140)
Query Neighborhood Hits	189	Target Neighborhood Hits	1004	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

LRRF2_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.080114 (rank : 126)
Query Neighborhood Hits	189	Target Neighborhood Hits	791	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MYH11_MOUSE
θ value	0.47712 (rank : 100)	NC score	0.095147 (rank : 80)
Query Neighborhood Hits	189	Target Neighborhood Hits	1777	Shared Neighborhood Hits	100
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

OPTN_MOUSE
θ value	0.47712 (rank : 101)	NC score	0.072726 (rank : 173)
Query Neighborhood Hits	189	Target Neighborhood Hits	1120	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

RADI_MOUSE
θ value	0.47712 (rank : 102)	NC score	0.047633 (rank : 486)
Query Neighborhood Hits	189	Target Neighborhood Hits	773	Shared Neighborhood Hits	78
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

CASP_HUMAN
θ value	0.62314 (rank : 103)	NC score	0.083007 (rank : 117)
Query Neighborhood Hits	189	Target Neighborhood Hits	1131	Shared Neighborhood Hits	89
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

ERC2_MOUSE
θ value	0.62314 (rank : 104)	NC score	0.073730 (rank : 168)
Query Neighborhood Hits	189	Target Neighborhood Hits	1166	Shared Neighborhood Hits	87
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

LRRF2_MOUSE
θ value	0.62314 (rank : 105)	NC score	0.084120 (rank : 113)
Query Neighborhood Hits	189	Target Neighborhood Hits	556	Shared Neighborhood Hits	76
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MYH6_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.092644 (rank : 90)
Query Neighborhood Hits	189	Target Neighborhood Hits	1501	Shared Neighborhood Hits	90
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH8_MOUSE
θ value	0.62314 (rank : 107)	NC score	0.097048 (rank : 76)
Query Neighborhood Hits	189	Target Neighborhood Hits	1600	Shared Neighborhood Hits	98
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SC11A_HUMAN
θ value	0.62314 (rank : 108)	NC score	0.011338 (rank : 516)
Query Neighborhood Hits	189	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SYCP1_MOUSE
θ value	0.62314 (rank : 109)	NC score	0.076029 (rank : 150)
Query Neighborhood Hits	189	Target Neighborhood Hits	1456	Shared Neighborhood Hits	90
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CALD1_HUMAN
θ value	0.813845 (rank : 110)	NC score	0.061653 (rank : 291)
Query Neighborhood Hits	189	Target Neighborhood Hits	959	Shared Neighborhood Hits	74
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

MYH11_HUMAN
θ value	0.813845 (rank : 111)	NC score	0.094162 (rank : 85)
Query Neighborhood Hits	189	Target Neighborhood Hits	1806	Shared Neighborhood Hits	98
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH3_HUMAN
θ value	0.813845 (rank : 112)	NC score	0.100529 (rank : 69)
Query Neighborhood Hits	189	Target Neighborhood Hits	1660	Shared Neighborhood Hits	100
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

OCRL_HUMAN
θ value	0.813845 (rank : 113)	NC score	0.283133 (rank : 61)
Query Neighborhood Hits	189	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

AMOL1_MOUSE
θ value	1.06291 (rank : 114)	NC score	0.058630 (rank : 337)
Query Neighborhood Hits	189	Target Neighborhood Hits	445	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

ERC2_HUMAN
θ value	1.06291 (rank : 115)	NC score	0.074261 (rank : 162)
Query Neighborhood Hits	189	Target Neighborhood Hits	1156	Shared Neighborhood Hits	87
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

FLIP1_HUMAN
θ value	1.06291 (rank : 116)	NC score	0.072277 (rank : 179)
Query Neighborhood Hits	189	Target Neighborhood Hits	1405	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MYH8_HUMAN
θ value	1.06291 (rank : 117)	NC score	0.098692 (rank : 73)
Query Neighborhood Hits	189	Target Neighborhood Hits	1610	Shared Neighborhood Hits	102
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

TFAP4_HUMAN
θ value	1.06291 (rank : 118)	NC score	0.043892 (rank : 488)
Query Neighborhood Hits	189	Target Neighborhood Hits	289	Shared Neighborhood Hits	42
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

CYLN2_MOUSE
θ value	1.38821 (rank : 119)	NC score	0.085200 (rank : 108)
Query Neighborhood Hits	189	Target Neighborhood Hits	1002	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

M3K10_HUMAN
θ value	1.38821 (rank : 120)	NC score	0.013167 (rank : 514)
Query Neighborhood Hits	189	Target Neighborhood Hits	1071	Shared Neighborhood Hits	50
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MY18A_HUMAN
θ value	1.38821 (rank : 121)	NC score	0.097596 (rank : 74)
Query Neighborhood Hits	189	Target Neighborhood Hits	1929	Shared Neighborhood Hits	103
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH9_MOUSE
θ value	1.38821 (rank : 122)	NC score	0.093891 (rank : 86)
Query Neighborhood Hits	189	Target Neighborhood Hits	1829	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

P85B_MOUSE
θ value	1.38821 (rank : 123)	NC score	0.110189 (rank : 65)
Query Neighborhood Hits	189	Target Neighborhood Hits	519	Shared Neighborhood Hits	75
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

TAXB1_MOUSE
θ value	1.38821 (rank : 124)	NC score	0.075072 (rank : 155)
Query Neighborhood Hits	189	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TPM4_MOUSE
θ value	1.38821 (rank : 125)	NC score	0.090927 (rank : 96)
Query Neighborhood Hits	189	Target Neighborhood Hits	703	Shared Neighborhood Hits	74
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

RB6I2_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.074957 (rank : 156)
Query Neighborhood Hits	189	Target Neighborhood Hits	1584	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SMC2_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.075469 (rank : 153)
Query Neighborhood Hits	189	Target Neighborhood Hits	1405	Shared Neighborhood Hits	92
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SNX23_HUMAN
θ value	1.81305 (rank : 128)	NC score	0.042941 (rank : 489)
Query Neighborhood Hits	189	Target Neighborhood Hits	944	Shared Neighborhood Hits	80
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

TPM4_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.094444 (rank : 84)
Query Neighborhood Hits	189	Target Neighborhood Hits	525	Shared Neighborhood Hits	70
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

ADIP_HUMAN
θ value	2.36792 (rank : 130)	NC score	0.052453 (rank : 444)
Query Neighborhood Hits	189	Target Neighborhood Hits	470	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

ATAD3_MOUSE
θ value	2.36792 (rank : 131)	NC score	0.031054 (rank : 498)
Query Neighborhood Hits	189	Target Neighborhood Hits	326	Shared Neighborhood Hits	48
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

CCD46_MOUSE
θ value	2.36792 (rank : 132)	NC score	0.076705 (rank : 146)
Query Neighborhood Hits	189	Target Neighborhood Hits	1405	Shared Neighborhood Hits	99
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CENPF_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.081908 (rank : 120)
Query Neighborhood Hits	189	Target Neighborhood Hits	1932	Shared Neighborhood Hits	105
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CJ118_MOUSE
θ value	2.36792 (rank : 134)	NC score	0.072546 (rank : 175)
Query Neighborhood Hits	189	Target Neighborhood Hits	1132	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

EVPL_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.057789 (rank : 352)
Query Neighborhood Hits	189	Target Neighborhood Hits	895	Shared Neighborhood Hits	84
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

KPCD_HUMAN
θ value	2.36792 (rank : 136)	NC score	0.039182 (rank : 492)
Query Neighborhood Hits	189	Target Neighborhood Hits	900	Shared Neighborhood Hits	49
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MYH2_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.094444 (rank : 83)
Query Neighborhood Hits	189	Target Neighborhood Hits	1491	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH4_MOUSE
θ value	2.36792 (rank : 138)	NC score	0.093830 (rank : 87)
Query Neighborhood Hits	189	Target Neighborhood Hits	1476	Shared Neighborhood Hits	97
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

AAKG3_HUMAN
θ value	3.0926 (rank : 139)	NC score	0.010461 (rank : 518)
Query Neighborhood Hits	189	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGI9, Q4QQG8, Q4V779, Q9NRL1	Gene names	PRKAG3, AMPKG3
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma-3 chain) (AMPK gamma3).

ARAF_HUMAN
θ value	3.0926 (rank : 140)	NC score	0.023566 (rank : 506)
Query Neighborhood Hits	189	Target Neighborhood Hits	924	Shared Neighborhood Hits	41
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	3.0926 (rank : 141)	NC score	0.023728 (rank : 504)
Query Neighborhood Hits	189	Target Neighborhood Hits	874	Shared Neighborhood Hits	41
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

C102B_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.067248 (rank : 219)
Query Neighborhood Hits	189	Target Neighborhood Hits	542	Shared Neighborhood Hits	70
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

DOK3_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.013612 (rank : 513)
Query Neighborhood Hits	189	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

GCC2_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.072681 (rank : 174)
Query Neighborhood Hits	189	Target Neighborhood Hits	1558	Shared Neighborhood Hits	99
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

KPCD_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.038332 (rank : 493)
Query Neighborhood Hits	189	Target Neighborhood Hits	888	Shared Neighborhood Hits	49
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MYH6_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.091439 (rank : 93)
Query Neighborhood Hits	189	Target Neighborhood Hits	1426	Shared Neighborhood Hits	89
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

RADI_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.042537 (rank : 491)
Query Neighborhood Hits	189	Target Neighborhood Hits	741	Shared Neighborhood Hits	74
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RAF1_HUMAN
θ value	3.0926 (rank : 148)	NC score	0.024035 (rank : 503)
Query Neighborhood Hits	189	Target Neighborhood Hits	886	Shared Neighborhood Hits	42
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	3.0926 (rank : 149)	NC score	0.023677 (rank : 505)
Query Neighborhood Hits	189	Target Neighborhood Hits	886	Shared Neighborhood Hits	42
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RASF5_MOUSE
θ value	3.0926 (rank : 150)	NC score	0.076190 (rank : 148)
Query Neighborhood Hits	189	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

RBP24_HUMAN
θ value	3.0926 (rank : 151)	NC score	0.072753 (rank : 172)
Query Neighborhood Hits	189	Target Neighborhood Hits	1559	Shared Neighborhood Hits	99
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

BRAF1_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.022065 (rank : 507)
Query Neighborhood Hits	189	Target Neighborhood Hits	883	Shared Neighborhood Hits	42
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

CING_MOUSE
θ value	4.03905 (rank : 153)	NC score	0.076029 (rank : 149)
Query Neighborhood Hits	189	Target Neighborhood Hits	1432	Shared Neighborhood Hits	93
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

DGKA_HUMAN
θ value	4.03905 (rank : 154)	NC score	0.042730 (rank : 490)
Query Neighborhood Hits	189	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKB_HUMAN
θ value	4.03905 (rank : 155)	NC score	0.061409 (rank : 296)
Query Neighborhood Hits	189	Target Neighborhood Hits	238	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

KPCT_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.035257 (rank : 495)
Query Neighborhood Hits	189	Target Neighborhood Hits	897	Shared Neighborhood Hits	46
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	4.03905 (rank : 157)	NC score	0.035356 (rank : 494)
Query Neighborhood Hits	189	Target Neighborhood Hits	895	Shared Neighborhood Hits	46
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

MY18A_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.095367 (rank : 79)
Query Neighborhood Hits	189	Target Neighborhood Hits	1989	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYCS_MOUSE
θ value	4.03905 (rank : 159)	NC score	0.010507 (rank : 517)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

CCD46_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.077581 (rank : 143)
Query Neighborhood Hits	189	Target Neighborhood Hits	1430	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

ITSN1_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.079698 (rank : 132)
Query Neighborhood Hits	189	Target Neighborhood Hits	1757	Shared Neighborhood Hits	109
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KPCA_HUMAN
θ value	5.27518 (rank : 162)	NC score	0.034421 (rank : 496)
Query Neighborhood Hits	189	Target Neighborhood Hits	1070	Shared Neighborhood Hits	51
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.033539 (rank : 497)
Query Neighborhood Hits	189	Target Neighborhood Hits	1067	Shared Neighborhood Hits	51
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCI_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.029289 (rank : 502)
Query Neighborhood Hits	189	Target Neighborhood Hits	885	Shared Neighborhood Hits	47
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

KPCI_MOUSE
θ value	5.27518 (rank : 165)	NC score	0.029544 (rank : 500)
Query Neighborhood Hits	189	Target Neighborhood Hits	888	Shared Neighborhood Hits	49
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

MYH10_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.090278 (rank : 99)
Query Neighborhood Hits	189	Target Neighborhood Hits	1620	Shared Neighborhood Hits	97
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SYCP1_HUMAN
θ value	5.27518 (rank : 167)	NC score	0.073241 (rank : 169)
Query Neighborhood Hits	189	Target Neighborhood Hits	1313	Shared Neighborhood Hits	91
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CCD39_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.073830 (rank : 167)
Query Neighborhood Hits	189	Target Neighborhood Hits	868	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CING_HUMAN
θ value	6.88961 (rank : 169)	NC score	0.074534 (rank : 159)
Query Neighborhood Hits	189	Target Neighborhood Hits	1275	Shared Neighborhood Hits	88
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

HRX_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.009917 (rank : 519)
Query Neighborhood Hits	189	Target Neighborhood Hits	825	Shared Neighborhood Hits	13
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

KPCZ_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.030252 (rank : 499)
Query Neighborhood Hits	189	Target Neighborhood Hits	884	Shared Neighborhood Hits	47
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KSR1_HUMAN
θ value	6.88961 (rank : 172)	NC score	0.020365 (rank : 510)
Query Neighborhood Hits	189	Target Neighborhood Hits	867	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

MYH10_MOUSE
θ value	6.88961 (rank : 173)	NC score	0.090323 (rank : 98)
Query Neighborhood Hits	189	Target Neighborhood Hits	1612	Shared Neighborhood Hits	97
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NUCKS_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.017277 (rank : 511)
Query Neighborhood Hits	189	Target Neighborhood Hits	143	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PDZD8_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.105914 (rank : 66)
Query Neighborhood Hits	189	Target Neighborhood Hits	185	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PLEC1_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.049404 (rank : 481)
Query Neighborhood Hits	189	Target Neighborhood Hits	1326	Shared Neighborhood Hits	82
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SPY2_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.005994 (rank : 522)
Query Neighborhood Hits	189	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

UN13A_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.090787 (rank : 97)
Query Neighborhood Hits	189	Target Neighborhood Hits	285	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	6.88961 (rank : 179)	NC score	0.091500 (rank : 92)
Query Neighborhood Hits	189	Target Neighborhood Hits	217	Shared Neighborhood Hits	48
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

LIPB1_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.054061 (rank : 423)
Query Neighborhood Hits	189	Target Neighborhood Hits	727	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MYH1_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.094813 (rank : 82)
Query Neighborhood Hits	189	Target Neighborhood Hits	1478	Shared Neighborhood Hits	97
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	8.99809 (rank : 182)	NC score	0.094813 (rank : 81)
Query Neighborhood Hits	189	Target Neighborhood Hits	1461	Shared Neighborhood Hits	98
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

NUCKS_MOUSE
θ value	8.99809 (rank : 183)	NC score	0.014088 (rank : 512)
Query Neighborhood Hits	189	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

RN123_MOUSE
θ value	8.99809 (rank : 184)	NC score	0.012998 (rank : 515)
Query Neighborhood Hits	189	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

STAC3_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.083358 (rank : 116)
Query Neighborhood Hits	189	Target Neighborhood Hits	228	Shared Neighborhood Hits	48
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.085030 (rank : 109)
Query Neighborhood Hits	189	Target Neighborhood Hits	232	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

TIMD4_MOUSE
θ value	8.99809 (rank : 187)	NC score	0.006806 (rank : 521)
Query Neighborhood Hits	189	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

WASF3_MOUSE
θ value	8.99809 (rank : 188)	NC score	0.007655 (rank : 520)
Query Neighborhood Hits	189	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ZN213_HUMAN
θ value	8.99809 (rank : 189)	NC score	-0.007540 (rank : 523)
Query Neighborhood Hits	189	Target Neighborhood Hits	755	Shared Neighborhood Hits	2
SwissProt Accessions	O14771, Q96IS1	Gene names	ZNF213
Domain Architecture
Description	Zinc finger protein 213 (Putative transcription factor CR53).

3BP5_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.062807 (rank : 272)
Query Neighborhood Hits	189	Target Neighborhood Hits	375	Shared Neighborhood Hits	67
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

3BP5_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.062241 (rank : 282)
Query Neighborhood Hits	189	Target Neighborhood Hits	346	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

AKAP9_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.066753 (rank : 225)
Query Neighborhood Hits	189	Target Neighborhood Hits	1710	Shared Neighborhood Hits	96
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

AMOL2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.050699 (rank : 469)
Query Neighborhood Hits	189	Target Neighborhood Hits	603	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

AMOL2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.051571 (rank : 454)
Query Neighborhood Hits	189	Target Neighborhood Hits	591	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

AMOT_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.051261 (rank : 460)
Query Neighborhood Hits	189	Target Neighborhood Hits	712	Shared Neighborhood Hits	67
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ANR26_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.060519 (rank : 306)
Query Neighborhood Hits	189	Target Neighborhood Hits	1614	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ARFG3_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.050019 (rank : 480)
Query Neighborhood Hits	189	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

AZI1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.063052 (rank : 267)
Query Neighborhood Hits	189	Target Neighborhood Hits	1000	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.065305 (rank : 238)
Query Neighborhood Hits	189	Target Neighborhood Hits	990	Shared Neighborhood Hits	85
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BICD1_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.065834 (rank : 232)
Query Neighborhood Hits	189	Target Neighborhood Hits	844	Shared Neighborhood Hits	83
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.068371 (rank : 208)
Query Neighborhood Hits	189	Target Neighborhood Hits	837	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD2_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.064081 (rank : 255)
Query Neighborhood Hits	189	Target Neighborhood Hits	856	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.063551 (rank : 259)
Query Neighborhood Hits	189	Target Neighborhood Hits	864	Shared Neighborhood Hits	85
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BNIP2_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.050654 (rank : 470)
Query Neighborhood Hits	189	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.050556 (rank : 471)
Query Neighborhood Hits	189	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BPA1_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.053120 (rank : 435)
Query Neighborhood Hits	189	Target Neighborhood Hits	1477	Shared Neighborhood Hits	89
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.063869 (rank : 256)
Query Neighborhood Hits	189	Target Neighborhood Hits	1480	Shared Neighborhood Hits	92
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRE1A_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.057181 (rank : 360)
Query Neighborhood Hits	189	Target Neighborhood Hits	1071	Shared Neighborhood Hits	82
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.058207 (rank : 349)
Query Neighborhood Hits	189	Target Neighborhood Hits	1025	Shared Neighborhood Hits	85
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1B_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.055288 (rank : 399)
Query Neighborhood Hits	189	Target Neighborhood Hits	1040	Shared Neighborhood Hits	79
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.055292 (rank : 398)
Query Neighborhood Hits	189	Target Neighborhood Hits	970	Shared Neighborhood Hits	78
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CAR11_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.060067 (rank : 316)
Query Neighborhood Hits	189	Target Neighborhood Hits	690	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CARD9_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.057488 (rank : 357)
Query Neighborhood Hits	189	Target Neighborhood Hits	602	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CCD11_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.050235 (rank : 476)
Query Neighborhood Hits	189	Target Neighborhood Hits	822	Shared Neighborhood Hits	75
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD11_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.052002 (rank : 448)
Query Neighborhood Hits	189	Target Neighborhood Hits	498	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD13_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.080018 (rank : 127)
Query Neighborhood Hits	189	Target Neighborhood Hits	721	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD19_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.050257 (rank : 475)
Query Neighborhood Hits	189	Target Neighborhood Hits	639	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.064777 (rank : 247)
Query Neighborhood Hits	189	Target Neighborhood Hits	1228	Shared Neighborhood Hits	81
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.061682 (rank : 290)
Query Neighborhood Hits	189	Target Neighborhood Hits	1135	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD39_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.074063 (rank : 165)
Query Neighborhood Hits	189	Target Neighborhood Hits	1026	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.058947 (rank : 333)
Query Neighborhood Hits	189	Target Neighborhood Hits	1139	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.063142 (rank : 266)
Query Neighborhood Hits	189	Target Neighborhood Hits	1399	Shared Neighborhood Hits	85
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD42_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.052053 (rank : 447)
Query Neighborhood Hits	189	Target Neighborhood Hits	406	Shared Neighborhood Hits	65
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD62_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.070398 (rank : 189)
Query Neighborhood Hits	189	Target Neighborhood Hits	631	Shared Neighborhood Hits	81
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD91_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.050852 (rank : 465)
Query Neighborhood Hits	189	Target Neighborhood Hits	699	Shared Neighborhood Hits	71
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD93_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.057785 (rank : 353)
Query Neighborhood Hits	189	Target Neighborhood Hits	600	Shared Neighborhood Hits	67
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CCD96_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.060998 (rank : 301)
Query Neighborhood Hits	189	Target Neighborhood Hits	595	Shared Neighborhood Hits	68
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD96_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.055241 (rank : 401)
Query Neighborhood Hits	189	Target Neighborhood Hits	704	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.056294 (rank : 376)
Query Neighborhood Hits	189	Target Neighborhood Hits	723	Shared Neighborhood Hits	77
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.059752 (rank : 322)
Query Neighborhood Hits	189	Target Neighborhood Hits	717	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.063019 (rank : 268)
Query Neighborhood Hits	189	Target Neighborhood Hits	932	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CDR2_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.058066 (rank : 351)
Query Neighborhood Hits	189	Target Neighborhood Hits	482	Shared Neighborhood Hits	72
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

CE152_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.070093 (rank : 191)
Query Neighborhood Hits	189	Target Neighborhood Hits	976	Shared Neighborhood Hits	84
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.072220 (rank : 180)
Query Neighborhood Hits	189	Target Neighborhood Hits	1553	Shared Neighborhood Hits	92
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENA1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.052520 (rank : 443)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.055633 (rank : 391)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.077933 (rank : 142)
Query Neighborhood Hits	189	Target Neighborhood Hits	383	Shared Neighborhood Hits	12
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.087589 (rank : 105)
Query Neighborhood Hits	189	Target Neighborhood Hits	425	Shared Neighborhood Hits	29
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.079886 (rank : 130)
Query Neighborhood Hits	189	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CEP55_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.063832 (rank : 257)
Query Neighborhood Hits	189	Target Neighborhood Hits	504	Shared Neighborhood Hits	74
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP55_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.064677 (rank : 249)
Query Neighborhood Hits	189	Target Neighborhood Hits	693	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP57_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.063745 (rank : 258)
Query Neighborhood Hits	189	Target Neighborhood Hits	576	Shared Neighborhood Hits	77
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

CEP57_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.066385 (rank : 229)
Query Neighborhood Hits	189	Target Neighborhood Hits	580	Shared Neighborhood Hits	77
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CEP63_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.069129 (rank : 200)
Query Neighborhood Hits	189	Target Neighborhood Hits	1005	Shared Neighborhood Hits	87
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CEP70_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.056151 (rank : 379)
Query Neighborhood Hits	189	Target Neighborhood Hits	432	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CEP70_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.051758 (rank : 452)
Query Neighborhood Hits	189	Target Neighborhood Hits	532	Shared Neighborhood Hits	72
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CF060_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.062815 (rank : 271)
Query Neighborhood Hits	189	Target Neighborhood Hits	1270	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CF152_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.062079 (rank : 283)
Query Neighborhood Hits	189	Target Neighborhood Hits	704	Shared Neighborhood Hits	80
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CF152_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.059296 (rank : 326)
Query Neighborhood Hits	189	Target Neighborhood Hits	597	Shared Neighborhood Hits	70
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

CF182_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.050460 (rank : 473)
Query Neighborhood Hits	189	Target Neighborhood Hits	551	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CI039_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.067646 (rank : 215)
Query Neighborhood Hits	189	Target Neighborhood Hits	1171	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.078451 (rank : 138)
Query Neighborhood Hits	189	Target Neighborhood Hits	1088	Shared Neighborhood Hits	95
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CIP4_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.079090 (rank : 135)
Query Neighborhood Hits	189	Target Neighborhood Hits	374	Shared Neighborhood Hits	60
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CK5P2_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.068147 (rank : 209)
Query Neighborhood Hits	189	Target Neighborhood Hits	1433	Shared Neighborhood Hits	92
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.067902 (rank : 213)
Query Neighborhood Hits	189	Target Neighborhood Hits	1151	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CKAP4_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.063375 (rank : 262)
Query Neighborhood Hits	189	Target Neighborhood Hits	592	Shared Neighborhood Hits	71
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CKAP4_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.061744 (rank : 288)
Query Neighborhood Hits	189	Target Neighborhood Hits	596	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CN145_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.072322 (rank : 178)
Query Neighborhood Hits	189	Target Neighborhood Hits	1196	Shared Neighborhood Hits	93
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CN145_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.068062 (rank : 210)
Query Neighborhood Hits	189	Target Neighborhood Hits	916	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CNTRB_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.052180 (rank : 445)
Query Neighborhood Hits	189	Target Neighborhood Hits	690	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CNTRB_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.057064 (rank : 362)
Query Neighborhood Hits	189	Target Neighborhood Hits	1029	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP135_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.069322 (rank : 195)
Query Neighborhood Hits	189	Target Neighborhood Hits	1290	Shared Neighborhood Hits	90
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.068996 (rank : 203)
Query Neighborhood Hits	189	Target Neighborhood Hits	1278	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP250_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.071288 (rank : 185)
Query Neighborhood Hits	189	Target Neighborhood Hits	1805	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP250_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.064659 (rank : 250)
Query Neighborhood Hits	189	Target Neighborhood Hits	1583	Shared Neighborhood Hits	94
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CR034_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.054888 (rank : 408)
Query Neighborhood Hits	189	Target Neighborhood Hits	538	Shared Neighborhood Hits	74
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CR034_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.068554 (rank : 207)
Query Neighborhood Hits	189	Target Neighborhood Hits	643	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CRCM_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.059435 (rank : 324)
Query Neighborhood Hits	189	Target Neighborhood Hits	520	Shared Neighborhood Hits	72
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

CT096_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.051535 (rank : 455)
Query Neighborhood Hits	189	Target Neighborhood Hits	438	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT2NL_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.068047 (rank : 211)
Query Neighborhood Hits	189	Target Neighborhood Hits	1059	Shared Neighborhood Hits	86
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.055907 (rank : 382)
Query Neighborhood Hits	189	Target Neighborhood Hits	902	Shared Neighborhood Hits	83
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CTGE5_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.054775 (rank : 411)
Query Neighborhood Hits	189	Target Neighborhood Hits	800	Shared Neighborhood Hits	77
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

CTGE5_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.060866 (rank : 304)
Query Neighborhood Hits	189	Target Neighborhood Hits	928	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CTGE6_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.055721 (rank : 388)
Query Neighborhood Hits	189	Target Neighborhood Hits	650	Shared Neighborhood Hits	76
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

CU013_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.051259 (rank : 461)
Query Neighborhood Hits	189	Target Neighborhood Hits	405	Shared Neighborhood Hits	63
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

CUTL2_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.058097 (rank : 350)
Query Neighborhood Hits	189	Target Neighborhood Hits	906	Shared Neighborhood Hits	69
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CUTL2_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.050513 (rank : 472)
Query Neighborhood Hits	189	Target Neighborhood Hits	771	Shared Neighborhood Hits	64
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CYTSA_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.063282 (rank : 264)
Query Neighborhood Hits	189	Target Neighborhood Hits	1138	Shared Neighborhood Hits	85
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.064324 (rank : 253)
Query Neighborhood Hits	189	Target Neighborhood Hits	1104	Shared Neighborhood Hits	87
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DAPP1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.055689 (rank : 389)
Query Neighborhood Hits	189	Target Neighborhood Hits	227	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.057261 (rank : 359)
Query Neighborhood Hits	189	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDEF1_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.055054 (rank : 404)
Query Neighborhood Hits	189	Target Neighborhood Hits	592	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.060255 (rank : 311)
Query Neighborhood Hits	189	Target Neighborhood Hits	599	Shared Neighborhood Hits	25
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.058312 (rank : 346)
Query Neighborhood Hits	189	Target Neighborhood Hits	625	Shared Neighborhood Hits	20
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.056961 (rank : 367)
Query Neighborhood Hits	189	Target Neighborhood Hits	353	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DESP_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.068680 (rank : 204)
Query Neighborhood Hits	189	Target Neighborhood Hits	1470	Shared Neighborhood Hits	94
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DGKD_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.066558 (rank : 228)
Query Neighborhood Hits	189	Target Neighborhood Hits	231	Shared Neighborhood Hits	51
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.074274 (rank : 161)
Query Neighborhood Hits	189	Target Neighborhood Hits	255	Shared Neighborhood Hits	47
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DLG5_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.057075 (rank : 361)
Query Neighborhood Hits	189	Target Neighborhood Hits	1088	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DMD_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.051027 (rank : 463)
Query Neighborhood Hits	189	Target Neighborhood Hits	1111	Shared Neighborhood Hits	83
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DP13A_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.058950 (rank : 332)
Query Neighborhood Hits	189	Target Neighborhood Hits	107	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.053988 (rank : 424)
Query Neighborhood Hits	189	Target Neighborhood Hits	96	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DYNA_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.060410 (rank : 309)
Query Neighborhood Hits	189	Target Neighborhood Hits	1194	Shared Neighborhood Hits	84
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.060208 (rank : 313)
Query Neighborhood Hits	189	Target Neighborhood Hits	1084	Shared Neighborhood Hits	84
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

EEA1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.064876 (rank : 245)
Query Neighborhood Hits	189	Target Neighborhood Hits	1796	Shared Neighborhood Hits	93
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EEA1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.061933 (rank : 285)
Query Neighborhood Hits	189	Target Neighborhood Hits	1637	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EP15R_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.058410 (rank : 344)
Query Neighborhood Hits	189	Target Neighborhood Hits	1083	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.056442 (rank : 373)
Query Neighborhood Hits	189	Target Neighborhood Hits	1135	Shared Neighborhood Hits	86
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.051470 (rank : 459)
Query Neighborhood Hits	189	Target Neighborhood Hits	1021	Shared Neighborhood Hits	82
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EVPL_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.053356 (rank : 432)
Query Neighborhood Hits	189	Target Neighborhood Hits	952	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FA13A_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.081097 (rank : 123)
Query Neighborhood Hits	189	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.079979 (rank : 128)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.058259 (rank : 348)
Query Neighborhood Hits	189	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.056753 (rank : 369)
Query Neighborhood Hits	189	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FLIP1_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.065099 (rank : 242)
Query Neighborhood Hits	189	Target Neighborhood Hits	1176	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FYCO1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.055540 (rank : 393)
Query Neighborhood Hits	189	Target Neighborhood Hits	1149	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.055246 (rank : 400)
Query Neighborhood Hits	189	Target Neighborhood Hits	1059	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GAS8_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.061927 (rank : 286)
Query Neighborhood Hits	189	Target Neighborhood Hits	819	Shared Neighborhood Hits	81
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.065244 (rank : 241)
Query Neighborhood Hits	189	Target Neighborhood Hits	622	Shared Neighborhood Hits	80
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCC1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.054668 (rank : 413)
Query Neighborhood Hits	189	Target Neighborhood Hits	887	Shared Neighborhood Hits	77
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.051227 (rank : 462)
Query Neighborhood Hits	189	Target Neighborhood Hits	777	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC2_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.072355 (rank : 177)
Query Neighborhood Hits	189	Target Neighborhood Hits	1619	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA1_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.065352 (rank : 237)
Query Neighborhood Hits	189	Target Neighborhood Hits	1222	Shared Neighborhood Hits	89
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA1_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.067753 (rank : 214)
Query Neighborhood Hits	189	Target Neighborhood Hits	994	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.054146 (rank : 422)
Query Neighborhood Hits	189	Target Neighborhood Hits	856	Shared Neighborhood Hits	79
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA2_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.063356 (rank : 263)
Query Neighborhood Hits	189	Target Neighborhood Hits	944	Shared Neighborhood Hits	85
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

GOGA3_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.064299 (rank : 254)
Query Neighborhood Hits	189	Target Neighborhood Hits	1317	Shared Neighborhood Hits	89
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.067078 (rank : 220)
Query Neighborhood Hits	189	Target Neighborhood Hits	1437	Shared Neighborhood Hits	90
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA4_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.069101 (rank : 201)
Query Neighborhood Hits	189	Target Neighborhood Hits	2034	Shared Neighborhood Hits	95
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA4_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.065794 (rank : 233)
Query Neighborhood Hits	189	Target Neighborhood Hits	1939	Shared Neighborhood Hits	96
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.065793 (rank : 234)
Query Neighborhood Hits	189	Target Neighborhood Hits	1168	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.066747 (rank : 226)
Query Neighborhood Hits	189	Target Neighborhood Hits	1434	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.063415 (rank : 260)
Query Neighborhood Hits	189	Target Neighborhood Hits	1007	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GOGB1_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.070930 (rank : 186)
Query Neighborhood Hits	189	Target Neighborhood Hits	2297	Shared Neighborhood Hits	104
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRAP1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.058472 (rank : 342)
Query Neighborhood Hits	189	Target Neighborhood Hits	944	Shared Neighborhood Hits	85
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GRAP1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.064732 (rank : 248)
Query Neighborhood Hits	189	Target Neighborhood Hits	1234	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GRAP_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.059094 (rank : 329)
Query Neighborhood Hits	189	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.056361 (rank : 375)
Query Neighborhood Hits	189	Target Neighborhood Hits	309	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.055820 (rank : 385)
Query Neighborhood Hits	189	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.055812 (rank : 386)
Query Neighborhood Hits	189	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HAP1_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.057041 (rank : 365)
Query Neighborhood Hits	189	Target Neighborhood Hits	606	Shared Neighborhood Hits	74
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HC127_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.051487 (rank : 457)
Query Neighborhood Hits	189	Target Neighborhood Hits	292	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.051487 (rank : 458)
Query Neighborhood Hits	189	Target Neighborhood Hits	292	Shared Neighborhood Hits	54
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

HIP1R_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.052932 (rank : 437)
Query Neighborhood Hits	189	Target Neighborhood Hits	809	Shared Neighborhood Hits	81
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.056663 (rank : 370)
Query Neighborhood Hits	189	Target Neighborhood Hits	959	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.057378 (rank : 358)
Query Neighborhood Hits	189	Target Neighborhood Hits	1016	Shared Neighborhood Hits	80
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HMMR_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.061517 (rank : 293)
Query Neighborhood Hits	189	Target Neighborhood Hits	1082	Shared Neighborhood Hits	83
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.078099 (rank : 141)
Query Neighborhood Hits	189	Target Neighborhood Hits	1178	Shared Neighborhood Hits	91
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOME2_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.058394 (rank : 345)
Query Neighborhood Hits	189	Target Neighborhood Hits	882	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

HOOK1_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.053382 (rank : 431)
Query Neighborhood Hits	189	Target Neighborhood Hits	942	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.056203 (rank : 378)
Query Neighborhood Hits	189	Target Neighborhood Hits	910	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.050073 (rank : 479)
Query Neighborhood Hits	189	Target Neighborhood Hits	714	Shared Neighborhood Hits	76
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HOOK3_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.070866 (rank : 187)
Query Neighborhood Hits	189	Target Neighborhood Hits	1070	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.068614 (rank : 205)
Query Neighborhood Hits	189	Target Neighborhood Hits	1007	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

I5P2_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.277160 (rank : 62)
Query Neighborhood Hits	189	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

IF3A_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.055398 (rank : 397)
Query Neighborhood Hits	189	Target Neighborhood Hits	875	Shared Neighborhood Hits	78
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.055186 (rank : 402)
Query Neighborhood Hits	189	Target Neighborhood Hits	871	Shared Neighborhood Hits	79
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.065670 (rank : 235)
Query Neighborhood Hits	189	Target Neighborhood Hits	949	Shared Neighborhood Hits	85
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.065303 (rank : 239)
Query Neighborhood Hits	189	Target Neighborhood Hits	939	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.065437 (rank : 236)
Query Neighborhood Hits	189	Target Neighborhood Hits	893	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.058803 (rank : 336)
Query Neighborhood Hits	189	Target Neighborhood Hits	959	Shared Neighborhood Hits	79
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INCE_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.050181 (rank : 477)
Query Neighborhood Hits	189	Target Neighborhood Hits	978	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.051612 (rank : 453)
Query Neighborhood Hits	189	Target Neighborhood Hits	903	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INVO_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.052859 (rank : 438)
Query Neighborhood Hits	189	Target Neighborhood Hits	636	Shared Neighborhood Hits	64
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

ITSN1_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.075334 (rank : 154)
Query Neighborhood Hits	189	Target Neighborhood Hits	1669	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.067448 (rank : 217)
Query Neighborhood Hits	189	Target Neighborhood Hits	1173	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.074671 (rank : 158)
Query Neighborhood Hits	189	Target Neighborhood Hits	1371	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

K0555_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.067058 (rank : 221)
Query Neighborhood Hits	189	Target Neighborhood Hits	880	Shared Neighborhood Hits	83
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

KINH_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.051498 (rank : 456)
Query Neighborhood Hits	189	Target Neighborhood Hits	1231	Shared Neighborhood Hits	89
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KMHN1_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.073109 (rank : 170)
Query Neighborhood Hits	189	Target Neighborhood Hits	950	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KMHN1_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.061062 (rank : 299)
Query Neighborhood Hits	189	Target Neighborhood Hits	949	Shared Neighborhood Hits	82
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

KNTC2_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.062953 (rank : 270)
Query Neighborhood Hits	189	Target Neighborhood Hits	673	Shared Neighborhood Hits	77
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KNTC2_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.056565 (rank : 372)
Query Neighborhood Hits	189	Target Neighborhood Hits	692	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KTN1_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.064445 (rank : 251)
Query Neighborhood Hits	189	Target Neighborhood Hits	1197	Shared Neighborhood Hits	88
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.066863 (rank : 222)
Query Neighborhood Hits	189	Target Neighborhood Hits	1324	Shared Neighborhood Hits	86
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LIPA1_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.063411 (rank : 261)
Query Neighborhood Hits	189	Target Neighborhood Hits	1294	Shared Neighborhood Hits	89
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LIPA2_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.058930 (rank : 334)
Query Neighborhood Hits	189	Target Neighborhood Hits	1044	Shared Neighborhood Hits	86
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.062608 (rank : 275)
Query Neighborhood Hits	189	Target Neighborhood Hits	1282	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LRC45_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.063011 (rank : 269)
Query Neighborhood Hits	189	Target Neighborhood Hits	933	Shared Neighborhood Hits	87
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.060974 (rank : 302)
Query Neighborhood Hits	189	Target Neighborhood Hits	959	Shared Neighborhood Hits	78
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF1_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.050774 (rank : 467)
Query Neighborhood Hits	189	Target Neighborhood Hits	625	Shared Neighborhood Hits	67
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

LUZP1_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.055866 (rank : 384)
Query Neighborhood Hits	189	Target Neighborhood Hits	739	Shared Neighborhood Hits	77
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LUZP1_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.057772 (rank : 354)
Query Neighborhood Hits	189	Target Neighborhood Hits	940	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MACF1_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.050116 (rank : 478)
Query Neighborhood Hits	189	Target Neighborhood Hits	1313	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MACOI_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.053964 (rank : 425)
Query Neighborhood Hits	189	Target Neighborhood Hits	650	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.054452 (rank : 418)
Query Neighborhood Hits	189	Target Neighborhood Hits	620	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MD1L1_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.059364 (rank : 325)
Query Neighborhood Hits	189	Target Neighborhood Hits	893	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.061597 (rank : 292)
Query Neighborhood Hits	189	Target Neighborhood Hits	1001	Shared Neighborhood Hits	84
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MIPO1_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.062544 (rank : 276)
Query Neighborhood Hits	189	Target Neighborhood Hits	486	Shared Neighborhood Hits	70
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MPP9_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.056903 (rank : 368)
Query Neighborhood Hits	189	Target Neighborhood Hits	529	Shared Neighborhood Hits	69
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

MRCKA_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.062381 (rank : 280)
Query Neighborhood Hits	189	Target Neighborhood Hits	1999	Shared Neighborhood Hits	127
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MRCKB_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.059848 (rank : 319)
Query Neighborhood Hits	189	Target Neighborhood Hits	2239	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRIP_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.054971 (rank : 406)
Query Neighborhood Hits	189	Target Neighborhood Hits	578	Shared Neighborhood Hits	72
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.054538 (rank : 416)
Query Neighborhood Hits	189	Target Neighborhood Hits	569	Shared Neighborhood Hits	69
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MY18B_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.085695 (rank : 107)
Query Neighborhood Hits	189	Target Neighborhood Hits	1299	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH13_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.090267 (rank : 100)
Query Neighborhood Hits	189	Target Neighborhood Hits	1504	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH14_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.084833 (rank : 112)
Query Neighborhood Hits	189	Target Neighborhood Hits	995	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.088431 (rank : 103)
Query Neighborhood Hits	189	Target Neighborhood Hits	1225	Shared Neighborhood Hits	86
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH7_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.089365 (rank : 102)
Query Neighborhood Hits	189	Target Neighborhood Hits	1559	Shared Neighborhood Hits	94
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYO10_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.099920 (rank : 71)
Query Neighborhood Hits	189	Target Neighborhood Hits	920	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO15_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.076580 (rank : 147)
Query Neighborhood Hits	189	Target Neighborhood Hits	671	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO15_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.077328 (rank : 144)
Query Neighborhood Hits	189	Target Neighborhood Hits	467	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO1A_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.069937 (rank : 192)
Query Neighborhood Hits	189	Target Neighborhood Hits	67	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBC5, Q9UQD7	Gene names	MYO1A, MYHL
Domain Architecture
Description	Myosin Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC).

MYO1B_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.069436 (rank : 194)
Query Neighborhood Hits	189	Target Neighborhood Hits	70	Shared Neighborhood Hits	20
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

MYO1B_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.069494 (rank : 193)
Query Neighborhood Hits	189	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

MYO1C_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.069166 (rank : 199)
Query Neighborhood Hits	189	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	O00159	Gene names	MYO1C
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMI-beta) (MMIb).

MYO1C_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.069267 (rank : 196)
Query Neighborhood Hits	189	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTI7, O08571, O08834, Q9QW54	Gene names	Myo1c
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMIb).

MYO1D_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.069188 (rank : 198)
Query Neighborhood Hits	189	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	O94832, Q8NHP9	Gene names	MYO1D, KIAA0727
Domain Architecture
Description	Myosin Id.

MYO1D_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.069101 (rank : 202)
Query Neighborhood Hits	189	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q5SYD0, Q5SSK7, Q8BWY5	Gene names	Myo1d
Domain Architecture	No domain graphic available
Description	Myosin Id.

MYO1E_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.079378 (rank : 134)
Query Neighborhood Hits	189	Target Neighborhood Hits	293	Shared Neighborhood Hits	33
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.080641 (rank : 125)
Query Neighborhood Hits	189	Target Neighborhood Hits	275	Shared Neighborhood Hits	33
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.080673 (rank : 124)
Query Neighborhood Hits	189	Target Neighborhood Hits	262	Shared Neighborhood Hits	32
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO5A_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.090965 (rank : 95)
Query Neighborhood Hits	189	Target Neighborhood Hits	1092	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.091003 (rank : 94)
Query Neighborhood Hits	189	Target Neighborhood Hits	1117	Shared Neighborhood Hits	86
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5B_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.086956 (rank : 106)
Query Neighborhood Hits	189	Target Neighborhood Hits	911	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO5C_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.093534 (rank : 88)
Query Neighborhood Hits	189	Target Neighborhood Hits	1206	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYO6_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.083911 (rank : 114)
Query Neighborhood Hits	189	Target Neighborhood Hits	727	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO6_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.081977 (rank : 119)
Query Neighborhood Hits	189	Target Neighborhood Hits	586	Shared Neighborhood Hits	62
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO7A_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.078662 (rank : 137)
Query Neighborhood Hits	189	Target Neighborhood Hits	209	Shared Neighborhood Hits	36
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.079894 (rank : 129)
Query Neighborhood Hits	189	Target Neighborhood Hits	235	Shared Neighborhood Hits	40
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

NAF1_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.055604 (rank : 392)
Query Neighborhood Hits	189	Target Neighborhood Hits	937	Shared Neighborhood Hits	81
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.054378 (rank : 420)
Query Neighborhood Hits	189	Target Neighborhood Hits	852	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NCK2_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.060756 (rank : 305)
Query Neighborhood Hits	189	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NDE1_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.064996 (rank : 244)
Query Neighborhood Hits	189	Target Neighborhood Hits	823	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NDE1_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.056369 (rank : 374)
Query Neighborhood Hits	189	Target Neighborhood Hits	602	Shared Neighborhood Hits	74
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

NEMO_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.064402 (rank : 252)
Query Neighborhood Hits	189	Target Neighborhood Hits	820	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NEMO_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.050821 (rank : 466)
Query Neighborhood Hits	189	Target Neighborhood Hits	658	Shared Neighborhood Hits	67
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NIN_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.072533 (rank : 176)
Query Neighborhood Hits	189	Target Neighborhood Hits	1416	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIN_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.067503 (rank : 216)
Query Neighborhood Hits	189	Target Neighborhood Hits	1376	Shared Neighborhood Hits	91
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NUF2_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.060409 (rank : 310)
Query Neighborhood Hits	189	Target Neighborhood Hits	661	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

NUMA1_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.061158 (rank : 298)
Query Neighborhood Hits	189	Target Neighborhood Hits	1523	Shared Neighborhood Hits	87
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

OFD1_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.054806 (rank : 410)
Query Neighborhood Hits	189	Target Neighborhood Hits	753	Shared Neighborhood Hits	78
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

OPTN_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.061511 (rank : 294)
Query Neighborhood Hits	189	Target Neighborhood Hits	827	Shared Neighborhood Hits	76
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

P55G_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.083719 (rank : 115)
Query Neighborhood Hits	189	Target Neighborhood Hits	451	Shared Neighborhood Hits	61
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.079563 (rank : 133)
Query Neighborhood Hits	189	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PCNT_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.060888 (rank : 303)
Query Neighborhood Hits	189	Target Neighborhood Hits	1551	Shared Neighborhood Hits	91
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PCNT_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.055652 (rank : 390)
Query Neighborhood Hits	189	Target Neighborhood Hits	1207	Shared Neighborhood Hits	81
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PCTL_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.053819 (rank : 427)
Query Neighborhood Hits	189	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.054394 (rank : 419)
Query Neighborhood Hits	189	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PEPL_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.059827 (rank : 321)
Query Neighborhood Hits	189	Target Neighborhood Hits	1141	Shared Neighborhood Hits	84
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.057007 (rank : 366)
Query Neighborhood Hits	189	Target Neighborhood Hits	1105	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PHLB2_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.056124 (rank : 380)
Query Neighborhood Hits	189	Target Neighborhood Hits	964	Shared Neighborhood Hits	81
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.053347 (rank : 433)
Query Neighborhood Hits	189	Target Neighborhood Hits	1016	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PIBF1_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.074002 (rank : 166)
Query Neighborhood Hits	189	Target Neighborhood Hits	1041	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PKHA1_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.058464 (rank : 343)
Query Neighborhood Hits	189	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.053035 (rank : 436)
Query Neighborhood Hits	189	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

POF1B_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.057048 (rank : 364)
Query Neighborhood Hits	189	Target Neighborhood Hits	494	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

POF1B_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.060469 (rank : 307)
Query Neighborhood Hits	189	Target Neighborhood Hits	530	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

RABE1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.069195 (rank : 197)
Query Neighborhood Hits	189	Target Neighborhood Hits	1104	Shared Neighborhood Hits	86
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.067447 (rank : 218)
Query Neighborhood Hits	189	Target Neighborhood Hits	1105	Shared Neighborhood Hits	86
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RABE2_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.056276 (rank : 377)
Query Neighborhood Hits	189	Target Neighborhood Hits	598	Shared Neighborhood Hits	80
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAD50_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.074370 (rank : 160)
Query Neighborhood Hits	189	Target Neighborhood Hits	1317	Shared Neighborhood Hits	92
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.072078 (rank : 181)
Query Neighborhood Hits	189	Target Neighborhood Hits	1366	Shared Neighborhood Hits	93
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RASF1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.074889 (rank : 157)
Query Neighborhood Hits	189	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF1_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.089756 (rank : 101)
Query Neighborhood Hits	189	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

RB6I2_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.071707 (rank : 182)
Query Neighborhood Hits	189	Target Neighborhood Hits	1433	Shared Neighborhood Hits	89
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBCC1_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.055873 (rank : 383)
Query Neighborhood Hits	189	Target Neighborhood Hits	1023	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBCC1_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.059846 (rank : 320)
Query Neighborhood Hits	189	Target Neighborhood Hits	1048	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

REST_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.075586 (rank : 151)
Query Neighborhood Hits	189	Target Neighborhood Hits	1506	Shared Neighborhood Hits	95
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFIP3_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.061923 (rank : 287)
Query Neighborhood Hits	189	Target Neighborhood Hits	1055	Shared Neighborhood Hits	88
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RFIP4_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.053854 (rank : 426)
Query Neighborhood Hits	189	Target Neighborhood Hits	785	Shared Neighborhood Hits	79
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RFIP4_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.052760 (rank : 441)
Query Neighborhood Hits	189	Target Neighborhood Hits	708	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RIMB1_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.052831 (rank : 439)
Query Neighborhood Hits	189	Target Neighborhood Hits	1479	Shared Neighborhood Hits	83
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.059102 (rank : 328)
Query Neighborhood Hits	189	Target Neighborhood Hits	1376	Shared Neighborhood Hits	92
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RPGR1_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.050439 (rank : 474)
Query Neighborhood Hits	189	Target Neighborhood Hits	578	Shared Neighborhood Hits	66
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RRBP1_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.062411 (rank : 279)
Query Neighborhood Hits	189	Target Neighborhood Hits	1306	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RRBP1_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.055418 (rank : 396)
Query Neighborhood Hits	189	Target Neighborhood Hits	1650	Shared Neighborhood Hits	89
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RUFY2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.057064 (rank : 363)
Query Neighborhood Hits	189	Target Neighborhood Hits	1208	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.050877 (rank : 464)
Query Neighborhood Hits	189	Target Neighborhood Hits	820	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

RUFY3_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.053553 (rank : 429)
Query Neighborhood Hits	189	Target Neighborhood Hits	594	Shared Neighborhood Hits	75
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

RUFY3_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.052721 (rank : 442)
Query Neighborhood Hits	189	Target Neighborhood Hits	579	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

SAS6_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.066687 (rank : 227)
Query Neighborhood Hits	189	Target Neighborhood Hits	791	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SAS6_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.066796 (rank : 223)
Query Neighborhood Hits	189	Target Neighborhood Hits	931	Shared Neighborhood Hits	85
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SDCG8_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.065005 (rank : 243)
Query Neighborhood Hits	189	Target Neighborhood Hits	1002	Shared Neighborhood Hits	81
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.064861 (rank : 246)
Query Neighborhood Hits	189	Target Neighborhood Hits	886	Shared Neighborhood Hits	81
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SM1L2_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.062491 (rank : 277)
Query Neighborhood Hits	189	Target Neighborhood Hits	1019	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SM1L2_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.071369 (rank : 184)
Query Neighborhood Hits	189	Target Neighborhood Hits	918	Shared Neighborhood Hits	87
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMAP1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.053318 (rank : 434)
Query Neighborhood Hits	189	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.053401 (rank : 430)
Query Neighborhood Hits	189	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMC1A_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.060134 (rank : 315)
Query Neighborhood Hits	189	Target Neighborhood Hits	1346	Shared Neighborhood Hits	86
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.061329 (rank : 297)
Query Neighborhood Hits	189	Target Neighborhood Hits	1384	Shared Neighborhood Hits	88
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC3_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.059742 (rank : 323)
Query Neighborhood Hits	189	Target Neighborhood Hits	1186	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.060192 (rank : 314)
Query Neighborhood Hits	189	Target Neighborhood Hits	1187	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC4_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.062490 (rank : 278)
Query Neighborhood Hits	189	Target Neighborhood Hits	937	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SMC4_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.051863 (rank : 450)
Query Neighborhood Hits	189	Target Neighborhood Hits	830	Shared Neighborhood Hits	77
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SMP1L_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.054993 (rank : 405)
Query Neighborhood Hits	189	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.054969 (rank : 407)
Query Neighborhood Hits	189	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SPAG5_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.054575 (rank : 415)
Query Neighborhood Hits	189	Target Neighborhood Hits	625	Shared Neighborhood Hits	71
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

SPAG5_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.055080 (rank : 403)
Query Neighborhood Hits	189	Target Neighborhood Hits	612	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SPC24_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.054619 (rank : 414)
Query Neighborhood Hits	189	Target Neighborhood Hits	324	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

SPTA1_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.057502 (rank : 356)
Query Neighborhood Hits	189	Target Neighborhood Hits	748	Shared Neighborhood Hits	84
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.055441 (rank : 395)
Query Neighborhood Hits	189	Target Neighborhood Hits	675	Shared Neighborhood Hits	83
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.058971 (rank : 331)
Query Neighborhood Hits	189	Target Neighborhood Hits	888	Shared Neighborhood Hits	86
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SPTB2_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.050709 (rank : 468)
Query Neighborhood Hits	189	Target Neighborhood Hits	748	Shared Neighborhood Hits	81
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.052168 (rank : 446)
Query Neighborhood Hits	189	Target Neighborhood Hits	770	Shared Neighborhood Hits	80
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

STAC_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.067960 (rank : 212)
Query Neighborhood Hits	189	Target Neighborhood Hits	276	Shared Neighborhood Hits	47
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.074170 (rank : 163)
Query Neighborhood Hits	189	Target Neighborhood Hits	268	Shared Neighborhood Hits	46
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SWP70_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.058553 (rank : 339)
Query Neighborhood Hits	189	Target Neighborhood Hits	973	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.060435 (rank : 308)
Query Neighborhood Hits	189	Target Neighborhood Hits	1097	Shared Neighborhood Hits	84
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYNE1_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.058515 (rank : 341)
Query Neighborhood Hits	189	Target Neighborhood Hits	1484	Shared Neighborhood Hits	95
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

T3JAM_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.062366 (rank : 281)
Query Neighborhood Hits	189	Target Neighborhood Hits	533	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TACC2_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.055452 (rank : 394)
Query Neighborhood Hits	189	Target Neighborhood Hits	856	Shared Neighborhood Hits	81
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.054516 (rank : 417)
Query Neighborhood Hits	189	Target Neighborhood Hits	774	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TACC3_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.058584 (rank : 338)
Query Neighborhood Hits	189	Target Neighborhood Hits	779	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TACC3_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.056609 (rank : 371)
Query Neighborhood Hits	189	Target Neighborhood Hits	607	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

TAXB1_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.073105 (rank : 171)
Query Neighborhood Hits	189	Target Neighborhood Hits	829	Shared Neighborhood Hits	85
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TCRG1_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.065980 (rank : 231)
Query Neighborhood Hits	189	Target Neighborhood Hits	929	Shared Neighborhood Hits	74
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.066079 (rank : 230)
Query Neighborhood Hits	189	Target Neighborhood Hits	947	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TEX9_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.075571 (rank : 152)
Query Neighborhood Hits	189	Target Neighborhood Hits	541	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TEX9_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.061438 (rank : 295)
Query Neighborhood Hits	189	Target Neighborhood Hits	581	Shared Neighborhood Hits	78
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TMF1_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.058541 (rank : 340)
Query Neighborhood Hits	189	Target Neighborhood Hits	987	Shared Neighborhood Hits	77
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TNIP3_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.059921 (rank : 318)
Query Neighborhood Hits	189	Target Neighborhood Hits	511	Shared Neighborhood Hits	72
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TPR_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.071650 (rank : 183)
Query Neighborhood Hits	189	Target Neighborhood Hits	1921	Shared Neighborhood Hits	100
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRAIP_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.059076 (rank : 330)
Query Neighborhood Hits	189	Target Neighborhood Hits	780	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.059245 (rank : 327)
Query Neighborhood Hits	189	Target Neighborhood Hits	745	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRAK1_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.059986 (rank : 317)
Query Neighborhood Hits	189	Target Neighborhood Hits	660	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TRHY_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.055730 (rank : 387)
Query Neighborhood Hits	189	Target Neighborhood Hits	1385	Shared Neighborhood Hits	81
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRIPB_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.066754 (rank : 224)
Query Neighborhood Hits	189	Target Neighborhood Hits	1587	Shared Neighborhood Hits	95
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TSC1_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.061994 (rank : 284)
Query Neighborhood Hits	189	Target Neighborhood Hits	765	Shared Neighborhood Hits	72
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TUFT1_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.058272 (rank : 347)
Query Neighborhood Hits	189	Target Neighborhood Hits	686	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

TUFT1_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.068582 (rank : 206)
Query Neighborhood Hits	189	Target Neighborhood Hits	732	Shared Neighborhood Hits	81
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

UACA_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.057628 (rank : 355)
Query Neighborhood Hits	189	Target Neighborhood Hits	1622	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UACA_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.058818 (rank : 335)
Query Neighborhood Hits	189	Target Neighborhood Hits	1620	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UN13B_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.084991 (rank : 110)
Query Neighborhood Hits	189	Target Neighborhood Hits	210	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UTRO_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.054220 (rank : 421)
Query Neighborhood Hits	189	Target Neighborhood Hits	960	Shared Neighborhood Hits	82
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

VAV2_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.061696 (rank : 289)
Query Neighborhood Hits	189	Target Neighborhood Hits	453	Shared Neighborhood Hits	51
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.061016 (rank : 300)
Query Neighborhood Hits	189	Target Neighborhood Hits	456	Shared Neighborhood Hits	46
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.070576 (rank : 188)
Query Neighborhood Hits	189	Target Neighborhood Hits	398	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.070282 (rank : 190)
Query Neighborhood Hits	189	Target Neighborhood Hits	404	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.052765 (rank : 440)
Query Neighborhood Hits	189	Target Neighborhood Hits	452	Shared Neighborhood Hits	54
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.054729 (rank : 412)
Query Neighborhood Hits	189	Target Neighborhood Hits	430	Shared Neighborhood Hits	49
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

XE7_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.051862 (rank : 451)
Query Neighborhood Hits	189	Target Neighborhood Hits	738	Shared Neighborhood Hits	71
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

YO11_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.054815 (rank : 409)
Query Neighborhood Hits	189	Target Neighborhood Hits	272	Shared Neighborhood Hits	56
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

Hits sorted by NC score

RGAP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	189	Target Neighborhood Hits	189	Shared Neighborhood Hits	189
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
NC score	0.981980 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	189	Target Neighborhood Hits	185	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CHIO_MOUSE
NC score	0.814998 (rank : 3)	θ value	1.24688e-25 (rank : 6)
Query Neighborhood Hits	189	Target Neighborhood Hits	130	Shared Neighborhood Hits	95
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG09_HUMAN
NC score	0.814131 (rank : 4)	θ value	1.52774e-15 (rank : 23)
Query Neighborhood Hits	189	Target Neighborhood Hits	186	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

GMIP_MOUSE
NC score	0.810910 (rank : 5)	θ value	3.63628e-17 (rank : 15)
Query Neighborhood Hits	189	Target Neighborhood Hits	202	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.809889 (rank : 6)	θ value	3.28887e-18 (rank : 13)
Query Neighborhood Hits	189	Target Neighborhood Hits	225	Shared Neighborhood Hits	91
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHIN_MOUSE
NC score	0.790536 (rank : 7)	θ value	2.42779e-29 (rank : 3)
Query Neighborhood Hits	189	Target Neighborhood Hits	229	Shared Neighborhood Hits	97
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG12_HUMAN
NC score	0.789096 (rank : 8)	θ value	8.10077e-17 (rank : 18)
Query Neighborhood Hits	189	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHIN_HUMAN
NC score	0.786786 (rank : 9)	θ value	1.2049e-28 (rank : 4)
Query Neighborhood Hits	189	Target Neighborhood Hits	227	Shared Neighborhood Hits	96
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG12_MOUSE
NC score	0.785021 (rank : 10)	θ value	2.35696e-16 (rank : 20)
Query Neighborhood Hits	189	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHIO_HUMAN
NC score	0.783402 (rank : 11)	θ value	2.77775e-25 (rank : 7)
Query Neighborhood Hits	189	Target Neighborhood Hits	220	Shared Neighborhood Hits	96
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG06_HUMAN
NC score	0.777791 (rank : 12)	θ value	1.86753e-13 (rank : 28)
Query Neighborhood Hits	189	Target Neighborhood Hits	114	Shared Neighborhood Hits	61
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.777077 (rank : 13)	θ value	1.09485e-13 (rank : 26)
Query Neighborhood Hits	189	Target Neighborhood Hits	105	Shared Neighborhood Hits	61
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

OPHN1_HUMAN
NC score	0.773101 (rank : 14)	θ value	1.47631e-18 (rank : 12)
Query Neighborhood Hits	189	Target Neighborhood Hits	161	Shared Neighborhood Hits	74
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
NC score	0.770196 (rank : 15)	θ value	5.60996e-18 (rank : 14)
Query Neighborhood Hits	189	Target Neighborhood Hits	174	Shared Neighborhood Hits	72
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

GRLF1_HUMAN
NC score	0.768148 (rank : 16)	θ value	1.86753e-13 (rank : 27)
Query Neighborhood Hits	189	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

3BP1_MOUSE
NC score	0.763676 (rank : 17)	θ value	3.64472e-09 (rank : 50)
Query Neighborhood Hits	189	Target Neighborhood Hits	238	Shared Neighborhood Hits	66
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG18_HUMAN
NC score	0.762627 (rank : 18)	θ value	9.26847e-13 (rank : 35)
Query Neighborhood Hits	189	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

3BP1_HUMAN
NC score	0.756206 (rank : 19)	θ value	9.26847e-13 (rank : 33)
Query Neighborhood Hits	189	Target Neighborhood Hits	376	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG18_MOUSE
NC score	0.755113 (rank : 20)	θ value	3.89403e-11 (rank : 42)
Query Neighborhood Hits	189	Target Neighborhood Hits	110	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

TCGAP_MOUSE
NC score	0.755000 (rank : 21)	θ value	6.20254e-17 (rank : 17)
Query Neighborhood Hits	189	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG01_HUMAN
NC score	0.751980 (rank : 22)	θ value	1.2105e-12 (rank : 36)
Query Neighborhood Hits	189	Target Neighborhood Hits	75	Shared Neighborhood Hits	61
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG05_MOUSE
NC score	0.747640 (rank : 23)	θ value	7.58209e-15 (rank : 25)
Query Neighborhood Hits	189	Target Neighborhood Hits	165	Shared Neighborhood Hits	78
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RBP1_MOUSE
NC score	0.743138 (rank : 24)	θ value	1.38178e-16 (rank : 19)
Query Neighborhood Hits	189	Target Neighborhood Hits	493	Shared Neighborhood Hits	116
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG05_HUMAN
NC score	0.741197 (rank : 25)	θ value	5.25075e-16 (rank : 21)
Query Neighborhood Hits	189	Target Neighborhood Hits	158	Shared Neighborhood Hits	73
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG26_HUMAN
NC score	0.740376 (rank : 26)	θ value	1.09232e-21 (rank : 10)
Query Neighborhood Hits	189	Target Neighborhood Hits	281	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

ABR_HUMAN
NC score	0.738423 (rank : 27)	θ value	7.56453e-23 (rank : 9)
Query Neighborhood Hits	189	Target Neighborhood Hits	166	Shared Neighborhood Hits	68
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG08_MOUSE
NC score	0.733985 (rank : 28)	θ value	1.47974e-10 (rank : 43)
Query Neighborhood Hits	189	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
NC score	0.729703 (rank : 29)	θ value	1.74796e-11 (rank : 40)
Query Neighborhood Hits	189	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RBP1_HUMAN
NC score	0.724943 (rank : 30)	θ value	6.85773e-16 (rank : 22)
Query Neighborhood Hits	189	Target Neighborhood Hits	521	Shared Neighborhood Hits	116
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

BCR_HUMAN
NC score	0.718298 (rank : 31)	θ value	2.69047e-20 (rank : 11)
Query Neighborhood Hits	189	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG25_MOUSE
NC score	0.715241 (rank : 32)	θ value	3.18553e-13 (rank : 30)
Query Neighborhood Hits	189	Target Neighborhood Hits	492	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.698630 (rank : 33)	θ value	4.16044e-13 (rank : 31)
Query Neighborhood Hits	189	Target Neighborhood Hits	550	Shared Neighborhood Hits	114
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG04_HUMAN
NC score	0.681367 (rank : 34)	θ value	1.02475e-11 (rank : 39)
Query Neighborhood Hits	189	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

TAGAP_MOUSE
NC score	0.678618 (rank : 35)	θ value	2.36244e-08 (rank : 53)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_HUMAN
NC score	0.678211 (rank : 36)	θ value	1.9326e-10 (rank : 45)
Query Neighborhood Hits	189	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

SRGP2_HUMAN
NC score	0.671428 (rank : 37)	θ value	4.59992e-12 (rank : 38)
Query Neighborhood Hits	189	Target Neighborhood Hits	331	Shared Neighborhood Hits	84
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

TCGAP_HUMAN
NC score	0.669249 (rank : 38)	θ value	6.20254e-17 (rank : 16)
Query Neighborhood Hits	189	Target Neighborhood Hits	872	Shared Neighborhood Hits	68
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SRGP2_MOUSE
NC score	0.663352 (rank : 39)	θ value	2.28291e-11 (rank : 41)
Query Neighborhood Hits	189	Target Neighborhood Hits	324	Shared Neighborhood Hits	86
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRGP1_HUMAN
NC score	0.657779 (rank : 40)	θ value	2.52405e-10 (rank : 46)
Query Neighborhood Hits	189	Target Neighborhood Hits	390	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
NC score	0.654196 (rank : 41)	θ value	2.36244e-08 (rank : 52)
Query Neighborhood Hits	189	Target Neighborhood Hits	432	Shared Neighborhood Hits	98
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG07_MOUSE
NC score	0.647882 (rank : 42)	θ value	3.08544e-08 (rank : 54)
Query Neighborhood Hits	189	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.643722 (rank : 43)	θ value	6.21693e-09 (rank : 51)
Query Neighborhood Hits	189	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CE005_HUMAN
NC score	0.637998 (rank : 44)	θ value	3.18553e-13 (rank : 29)
Query Neighborhood Hits	189	Target Neighborhood Hits	213	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CEND2_HUMAN
NC score	0.636313 (rank : 45)	θ value	3.40345e-15 (rank : 24)
Query Neighborhood Hits	189	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CE005_MOUSE
NC score	0.635436 (rank : 46)	θ value	7.09661e-13 (rank : 32)
Query Neighborhood Hits	189	Target Neighborhood Hits	238	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

STAR8_MOUSE
NC score	0.614521 (rank : 47)	θ value	1.63604e-09 (rank : 48)
Query Neighborhood Hits	189	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.608755 (rank : 48)	θ value	1.9326e-10 (rank : 44)
Query Neighborhood Hits	189	Target Neighborhood Hits	216	Shared Neighborhood Hits	59
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND3_MOUSE
NC score	0.598448 (rank : 49)	θ value	9.26847e-13 (rank : 34)
Query Neighborhood Hits	189	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

STA13_HUMAN
NC score	0.591726 (rank : 50)	θ value	3.77169e-06 (rank : 57)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

CEND3_HUMAN
NC score	0.586761 (rank : 51)	θ value	1.58096e-12 (rank : 37)
Query Neighborhood Hits	189	Target Neighborhood Hits	275	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

STA13_MOUSE
NC score	0.582236 (rank : 52)	θ value	6.43352e-06 (rank : 58)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

K1688_MOUSE
NC score	0.546844 (rank : 53)	θ value	3.77169e-06 (rank : 56)
Query Neighborhood Hits	189	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

CEND1_MOUSE
NC score	0.544324 (rank : 54)	θ value	3.29651e-10 (rank : 47)
Query Neighborhood Hits	189	Target Neighborhood Hits	260	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

K1688_HUMAN
NC score	0.535090 (rank : 55)	θ value	2.21117e-06 (rank : 55)
Query Neighborhood Hits	189	Target Neighborhood Hits	217	Shared Neighborhood Hits	57
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND1_HUMAN
NC score	0.521429 (rank : 56)	θ value	2.13673e-09 (rank : 49)
Query Neighborhood Hits	189	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MYO9B_MOUSE
NC score	0.471120 (rank : 57)	θ value	3.62785e-25 (rank : 8)
Query Neighborhood Hits	189	Target Neighborhood Hits	311	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.465227 (rank : 58)	θ value	5.59698e-26 (rank : 5)
Query Neighborhood Hits	189	Target Neighborhood Hits	641	Shared Neighborhood Hits	114
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.405583 (rank : 59)	θ value	5.44631e-05 (rank : 59)
Query Neighborhood Hits	189	Target Neighborhood Hits	479	Shared Neighborhood Hits	102
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.392871 (rank : 60)	θ value	0.00035302 (rank : 60)
Query Neighborhood Hits	189	Target Neighborhood Hits	435	Shared Neighborhood Hits	89
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

OCRL_HUMAN
NC score	0.283133 (rank : 61)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	189	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

I5P2_HUMAN
NC score	0.277160 (rank : 62)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	189	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

GRP3_HUMAN
NC score	0.158684 (rank : 63)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

P85B_HUMAN
NC score	0.148912 (rank : 64)	θ value	0.00390308 (rank : 61)
Query Neighborhood Hits	189	Target Neighborhood Hits	543	Shared Neighborhood Hits	80
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
NC score	0.110189 (rank : 65)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	189	Target Neighborhood Hits	519	Shared Neighborhood Hits	75
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PDZD8_HUMAN
NC score	0.105914 (rank : 66)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	189	Target Neighborhood Hits	185	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

TPM1_HUMAN
NC score	0.103318 (rank : 67)	θ value	0.0330416 (rank : 67)
Query Neighborhood Hits	189	Target Neighborhood Hits	716	Shared Neighborhood Hits	79
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
NC score	0.102962 (rank : 68)	θ value	0.0330416 (rank : 68)
Query Neighborhood Hits	189	Target Neighborhood Hits	729	Shared Neighborhood Hits	80
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

MYH3_HUMAN
NC score	0.100529 (rank : 69)	θ value	0.813845 (rank : 112)
Query Neighborhood Hits	189	Target Neighborhood Hits	1660	Shared Neighborhood Hits	100
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TPM3_MOUSE
NC score	0.100515 (rank : 70)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	189	Target Neighborhood Hits	676	Shared Neighborhood Hits	70
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

MYO10_HUMAN
NC score	0.099920 (rank : 71)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	189	Target Neighborhood Hits	920	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

TPM3_HUMAN
NC score	0.098782 (rank : 72)	θ value	0.0961366 (rank : 78)
Query Neighborhood Hits	189	Target Neighborhood Hits	689	Shared Neighborhood Hits	70
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

MYH8_HUMAN
NC score	0.098692 (rank : 73)	θ value	1.06291 (rank : 117)
Query Neighborhood Hits	189	Target Neighborhood Hits	1610	Shared Neighborhood Hits	102
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MY18A_HUMAN
NC score	0.097596 (rank : 74)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	189	Target Neighborhood Hits	1929	Shared Neighborhood Hits	103
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TPM2_HUMAN
NC score	0.097116 (rank : 75)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	189	Target Neighborhood Hits	677	Shared Neighborhood Hits	76
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

MYH8_MOUSE
NC score	0.097048 (rank : 76)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	189	Target Neighborhood Hits	1600	Shared Neighborhood Hits	98
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

TPM2_MOUSE
NC score	0.096734 (rank : 77)	θ value	0.279714 (rank : 91)
Query Neighborhood Hits	189	Target Neighborhood Hits	676	Shared Neighborhood Hits	78
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

MYH4_HUMAN
NC score	0.096083 (rank : 78)	θ value	0.21417 (rank : 86)
Query Neighborhood Hits	189	Target Neighborhood Hits	1377	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MY18A_MOUSE
NC score	0.095367 (rank : 79)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	189	Target Neighborhood Hits	1989	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH11_MOUSE
NC score	0.095147 (rank : 80)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	189	Target Neighborhood Hits	1777	Shared Neighborhood Hits	100
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH1_MOUSE
NC score	0.094813 (rank : 81)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	189	Target Neighborhood Hits	1461	Shared Neighborhood Hits	98
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH1_HUMAN
NC score	0.094813 (rank : 82)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	189	Target Neighborhood Hits	1478	Shared Neighborhood Hits	97
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH2_HUMAN
NC score	0.094444 (rank : 83)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	189	Target Neighborhood Hits	1491	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

TPM4_HUMAN
NC score	0.094444 (rank : 84)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	189	Target Neighborhood Hits	525	Shared Neighborhood Hits	70
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

MYH11_HUMAN
NC score	0.094162 (rank : 85)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	189	Target Neighborhood Hits	1806	Shared Neighborhood Hits	98
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
NC score	0.093891 (rank : 86)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	189	Target Neighborhood Hits	1829	Shared Neighborhood Hits	99
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH4_MOUSE
NC score	0.093830 (rank : 87)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	189	Target Neighborhood Hits	1476	Shared Neighborhood Hits	97
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYO5C_HUMAN
NC score	0.093534 (rank : 88)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	189	Target Neighborhood Hits	1206	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYH9_HUMAN
NC score	0.093255 (rank : 89)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	189	Target Neighborhood Hits	1762	Shared Neighborhood Hits	98
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH6_MOUSE
NC score	0.092644 (rank : 90)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	189	Target Neighborhood Hits	1501	Shared Neighborhood Hits	90
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

DGKQ_HUMAN
NC score	0.092288 (rank : 91)	θ value	0.163984 (rank : 81)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

UN13B_HUMAN
NC score	0.091500 (rank : 92)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	189	Target Neighborhood Hits	217	Shared Neighborhood Hits	48
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

MYH6_HUMAN
NC score	0.091439 (rank : 93)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	189	Target Neighborhood Hits	1426	Shared Neighborhood Hits	89
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYO5A_MOUSE
NC score	0.091003 (rank : 94)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	189	Target Neighborhood Hits	1117	Shared Neighborhood Hits	86
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5A_HUMAN
NC score	0.090965 (rank : 95)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	189	Target Neighborhood Hits	1092	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

TPM4_MOUSE
NC score	0.090927 (rank : 96)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	189	Target Neighborhood Hits	703	Shared Neighborhood Hits	74
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

UN13A_HUMAN
NC score	0.090787 (rank : 97)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	189	Target Neighborhood Hits	285	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

MYH10_MOUSE
NC score	0.090323 (rank : 98)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	189	Target Neighborhood Hits	1612	Shared Neighborhood Hits	97
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	0.090278 (rank : 99)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	189	Target Neighborhood Hits	1620	Shared Neighborhood Hits	97
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH13_HUMAN
NC score	0.090267 (rank : 100)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	189	Target Neighborhood Hits	1504	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

RASF1_MOUSE
NC score	0.089756 (rank : 101)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	189	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

MYH7_HUMAN
NC score	0.089365 (rank : 102)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	189	Target Neighborhood Hits	1559	Shared Neighborhood Hits	94
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH14_MOUSE
NC score	0.088431 (rank : 103)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	189	Target Neighborhood Hits	1225	Shared Neighborhood Hits	86
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

RASF5_HUMAN
NC score	0.087898 (rank : 104)	θ value	0.365318 (rank : 95)
Query Neighborhood Hits	189	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

CENB2_HUMAN
NC score	0.087589 (rank : 105)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	189	Target Neighborhood Hits	425	Shared Neighborhood Hits	29
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

MYO5B_HUMAN
NC score	0.086956 (rank : 106)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	189	Target Neighborhood Hits	911	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MY18B_HUMAN
NC score	0.085695 (rank : 107)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	189	Target Neighborhood Hits	1299	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CYLN2_MOUSE
NC score	0.085200 (rank : 108)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	189	Target Neighborhood Hits	1002	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

STAC3_MOUSE
NC score	0.085030 (rank : 109)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	189	Target Neighborhood Hits	232	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

UN13B_MOUSE
NC score	0.084991 (rank : 110)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	189	Target Neighborhood Hits	210	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CASP_MOUSE
NC score	0.084944 (rank : 111)	θ value	0.163984 (rank : 79)
Query Neighborhood Hits	189	Target Neighborhood Hits	1152	Shared Neighborhood Hits	90
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

MYH14_HUMAN
NC score	0.084833 (rank : 112)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	189	Target Neighborhood Hits	995	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

LRRF2_MOUSE
NC score	0.084120 (rank : 113)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	189	Target Neighborhood Hits	556	Shared Neighborhood Hits	76
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MYO6_HUMAN
NC score	0.083911 (rank : 114)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	189	Target Neighborhood Hits	727	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

P55G_HUMAN
NC score	0.083719 (rank : 115)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	189	Target Neighborhood Hits	451	Shared Neighborhood Hits	61
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

STAC3_HUMAN
NC score	0.083358 (rank : 116)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	189	Target Neighborhood Hits	228	Shared Neighborhood Hits	48
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CASP_HUMAN
NC score	0.083007 (rank : 117)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	189	Target Neighborhood Hits	1131	Shared Neighborhood Hits	89
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CROCC_HUMAN
NC score	0.082091 (rank : 118)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	189	Target Neighborhood Hits	1409	Shared Neighborhood Hits	93
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MYO6_MOUSE
NC score	0.081977 (rank : 119)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	189	Target Neighborhood Hits	586	Shared Neighborhood Hits	62
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

CENPF_HUMAN
NC score	0.081908 (rank : 120)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	189	Target Neighborhood Hits	1932	Shared Neighborhood Hits	105
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CJ118_HUMAN
NC score	0.081856 (rank : 121)	θ value	0.00869519 (rank : 62)
Query Neighborhood Hits	189	Target Neighborhood Hits	937	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

REST_HUMAN
NC score	0.081698 (rank : 122)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	189	Target Neighborhood Hits	1605	Shared Neighborhood Hits	90
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

FA13A_HUMAN
NC score	0.081097 (rank : 123)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	189	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

MYO1F_MOUSE
NC score	0.080673 (rank : 124)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	189	Target Neighborhood Hits	262	Shared Neighborhood Hits	32
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO1F_HUMAN
NC score	0.080641 (rank : 125)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	189	Target Neighborhood Hits	275	Shared Neighborhood Hits	33
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

LRRF2_HUMAN
NC score	0.080114 (rank : 126)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	189	Target Neighborhood Hits	791	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

CCD13_HUMAN
NC score	0.080018 (rank : 127)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	189	Target Neighborhood Hits	721	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

FA13A_MOUSE
NC score	0.079979 (rank : 128)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

MYO7A_MOUSE
NC score	0.079894 (rank : 129)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	189	Target Neighborhood Hits	235	Shared Neighborhood Hits	40
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CENB5_HUMAN
NC score	0.079886 (rank : 130)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	189	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CUTL1_MOUSE
NC score	0.079835 (rank : 131)	θ value	0.163984 (rank : 80)
Query Neighborhood Hits	189	Target Neighborhood Hits	1620	Shared Neighborhood Hits	93
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ITSN1_HUMAN
NC score	0.079698 (rank : 132)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	189	Target Neighborhood Hits	1757	Shared Neighborhood Hits	109
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

P55G_MOUSE
NC score	0.079563 (rank : 133)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	189	Target Neighborhood Hits	401	Shared Neighborhood Hits	55
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

MYO1E_HUMAN
NC score	0.079378 (rank : 134)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	189	Target Neighborhood Hits	293	Shared Neighborhood Hits	33
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

CIP4_HUMAN
NC score	0.079090 (rank : 135)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	189	Target Neighborhood Hits	374	Shared Neighborhood Hits	60
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

RGNEF_MOUSE
NC score	0.078766 (rank : 136)	θ value	0.0193708 (rank : 66)
Query Neighborhood Hits	189	Target Neighborhood Hits	641	Shared Neighborhood Hits	94
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

MYO7A_HUMAN
NC score	0.078662 (rank : 137)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	189	Target Neighborhood Hits	209	Shared Neighborhood Hits	36
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CI093_HUMAN
NC score	0.078451 (rank : 138)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	189	Target Neighborhood Hits	1088	Shared Neighborhood Hits	95
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CROCC_MOUSE
NC score	0.078426 (rank : 139)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	189	Target Neighborhood Hits	1460	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CYLN2_HUMAN
NC score	0.078382 (rank : 140)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	189	Target Neighborhood Hits	1004	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

HMMR_MOUSE
NC score	0.078099 (rank : 141)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	189	Target Neighborhood Hits	1178	Shared Neighborhood Hits	91
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CENB1_HUMAN
NC score	0.077933 (rank : 142)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	189	Target Neighborhood Hits	383	Shared Neighborhood Hits	12
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CCD46_HUMAN
NC score	0.077581 (rank : 143)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	189	Target Neighborhood Hits	1430	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

MYO15_MOUSE
NC score	0.077328 (rank : 144)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	189	Target Neighborhood Hits	467	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SMC2_MOUSE
NC score	0.076963 (rank : 145)	θ value	0.279714 (rank : 90)
Query Neighborhood Hits	189	Target Neighborhood Hits	1131	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

CCD46_MOUSE
NC score	0.076705 (rank : 146)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	189	Target Neighborhood Hits	1405	Shared Neighborhood Hits	99
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

MYO15_HUMAN
NC score	0.076580 (rank : 147)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	189	Target Neighborhood Hits	671	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RASF5_MOUSE
NC score	0.076190 (rank : 148)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	189	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

CING_MOUSE
NC score	0.076029 (rank : 149)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	189	Target Neighborhood Hits	1432	Shared Neighborhood Hits	93
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

SYCP1_MOUSE
NC score	0.076029 (rank : 150)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	189	Target Neighborhood Hits	1456	Shared Neighborhood Hits	90
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

REST_MOUSE
NC score	0.075586 (rank : 151)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	189	Target Neighborhood Hits	1506	Shared Neighborhood Hits	95
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TEX9_HUMAN
NC score	0.075571 (rank : 152)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	189	Target Neighborhood Hits	541	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

SMC2_HUMAN
NC score	0.075469 (rank : 153)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	189	Target Neighborhood Hits	1405	Shared Neighborhood Hits	92
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

ITSN1_MOUSE
NC score	0.075334 (rank : 154)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	189	Target Neighborhood Hits	1669	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

TAXB1_MOUSE
NC score	0.075072 (rank : 155)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	189	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

RB6I2_HUMAN
NC score	0.074957 (rank : 156)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	189	Target Neighborhood Hits	1584	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RASF1_HUMAN
NC score	0.074889 (rank : 157)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	189	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

ITSN2_MOUSE
NC score	0.074671 (rank : 158)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	189	Target Neighborhood Hits	1371	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

CING_HUMAN
NC score	0.074534 (rank : 159)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	189	Target Neighborhood Hits	1275	Shared Neighborhood Hits	88
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

RAD50_HUMAN
NC score	0.074370 (rank : 160)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	189	Target Neighborhood Hits	1317	Shared Neighborhood Hits	92
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

DGKH_HUMAN
NC score	0.074274 (rank : 161)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	189	Target Neighborhood Hits	255	Shared Neighborhood Hits	47
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

ERC2_HUMAN
NC score	0.074261 (rank : 162)	θ value	1.06291 (rank : 115)
Query Neighborhood Hits	189	Target Neighborhood Hits	1156	Shared Neighborhood Hits	87
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

STAC_MOUSE
NC score	0.074170 (rank : 163)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	189	Target Neighborhood Hits	268	Shared Neighborhood Hits	46
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CUTL1_HUMAN
NC score	0.074096 (rank : 164)	θ value	0.21417 (rank : 84)
Query Neighborhood Hits	189	Target Neighborhood Hits	1574	Shared Neighborhood Hits	85
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CCD39_MOUSE
NC score	0.074063 (rank : 165)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	189	Target Neighborhood Hits	1026	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

PIBF1_HUMAN
NC score	0.074002 (rank : 166)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	189	Target Neighborhood Hits	1041	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

CCD39_HUMAN
NC score	0.073830 (rank : 167)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	189	Target Neighborhood Hits	868	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

ERC2_MOUSE
NC score	0.073730 (rank : 168)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	189	Target Neighborhood Hits	1166	Shared Neighborhood Hits	87
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

SYCP1_HUMAN
NC score	0.073241 (rank : 169)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	189	Target Neighborhood Hits	1313	Shared Neighborhood Hits	91
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

KMHN1_HUMAN
NC score	0.073109 (rank : 170)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	189	Target Neighborhood Hits	950	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

TAXB1_HUMAN
NC score	0.073105 (rank : 171)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	189	Target Neighborhood Hits	829	Shared Neighborhood Hits	85
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

RBP24_HUMAN
NC score	0.072753 (rank : 172)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	189	Target Neighborhood Hits	1559	Shared Neighborhood Hits	99
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

OPTN_MOUSE
NC score	0.072726 (rank : 173)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	189	Target Neighborhood Hits	1120	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

GCC2_HUMAN
NC score	0.072681 (rank : 174)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	189	Target Neighborhood Hits	1558	Shared Neighborhood Hits	99
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

CJ118_MOUSE
NC score	0.072546 (rank : 175)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	189	Target Neighborhood Hits	1132	Shared Neighborhood Hits	83
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

NIN_HUMAN
NC score	0.072533 (rank : 176)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	189	Target Neighborhood Hits	1416	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

GCC2_MOUSE
NC score	0.072355 (rank : 177)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	189	Target Neighborhood Hits	1619	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CN145_HUMAN
NC score	0.072322 (rank : 178)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	189	Target Neighborhood Hits	1196	Shared Neighborhood Hits	93
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

FLIP1_HUMAN
NC score	0.072277 (rank : 179)	θ value	1.06291 (rank : 116)
Query Neighborhood Hits	189	Target Neighborhood Hits	1405	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CE290_HUMAN
NC score	0.072220 (rank : 180)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	189	Target Neighborhood Hits	1553	Shared Neighborhood Hits	92
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

RAD50_MOUSE
NC score	0.072078 (rank : 181)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	189	Target Neighborhood Hits	1366	Shared Neighborhood Hits	93
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RB6I2_MOUSE
NC score	0.071707 (rank : 182)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	189	Target Neighborhood Hits	1433	Shared Neighborhood Hits	89
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TPR_HUMAN
NC score	0.071650 (rank : 183)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	189	Target Neighborhood Hits	1921	Shared Neighborhood Hits	100
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SM1L2_MOUSE
NC score	0.071369 (rank : 184)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	189	Target Neighborhood Hits	918	Shared Neighborhood Hits	87
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

CP250_HUMAN
NC score	0.071288 (rank : 185)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	189	Target Neighborhood Hits	1805	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GOGB1_HUMAN
NC score	0.070930 (rank : 186)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	189	Target Neighborhood Hits	2297	Shared Neighborhood Hits	104
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HOOK3_HUMAN
NC score	0.070866 (rank : 187)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	189	Target Neighborhood Hits	1070	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

VAV3_HUMAN
NC score	0.070576 (rank : 188)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	189	Target Neighborhood Hits	398	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

CCD62_HUMAN
NC score	0.070398 (rank : 189)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	189	Target Neighborhood Hits	631	Shared Neighborhood Hits	81
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

VAV3_MOUSE
NC score	0.070282 (rank : 190)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	189	Target Neighborhood Hits	404	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

CE152_HUMAN
NC score	0.070093 (rank : 191)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	189	Target Neighborhood Hits	976	Shared Neighborhood Hits	84
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

MYO1A_HUMAN
NC score	0.069937 (rank : 192)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	189	Target Neighborhood Hits	67	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBC5, Q9UQD7	Gene names	MYO1A, MYHL
Domain Architecture
Description	Myosin Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC).

MYO1B_MOUSE
NC score	0.069494 (rank : 193)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	189	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

MYO1B_HUMAN
NC score	0.069436 (rank : 194)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	189	Target Neighborhood Hits	70	Shared Neighborhood Hits	20
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

CP135_HUMAN
NC score	0.069322 (rank : 195)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	189	Target Neighborhood Hits	1290	Shared Neighborhood Hits	90
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYO1C_MOUSE
NC score	0.069267 (rank : 196)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	189	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTI7, O08571, O08834, Q9QW54	Gene names	Myo1c
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMIb).

RABE1_HUMAN
NC score	0.069195 (rank : 197)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	189	Target Neighborhood Hits	1104	Shared Neighborhood Hits	86
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

MYO1D_HUMAN
NC score	0.069188 (rank : 198)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	189	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	O94832, Q8NHP9	Gene names	MYO1D, KIAA0727
Domain Architecture
Description	Myosin Id.

MYO1C_HUMAN
NC score	0.069166 (rank : 199)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	189	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	O00159	Gene names	MYO1C
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMI-beta) (MMIb).

CEP63_HUMAN
NC score	0.069129 (rank : 200)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	189	Target Neighborhood Hits	1005	Shared Neighborhood Hits	87
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

GOGA4_HUMAN
NC score	0.069101 (rank : 201)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	189	Target Neighborhood Hits	2034	Shared Neighborhood Hits	95
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MYO1D_MOUSE
NC score	0.069101 (rank : 202)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	189	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q5SYD0, Q5SSK7, Q8BWY5	Gene names	Myo1d
Domain Architecture	No domain graphic available
Description	Myosin Id.

CP135_MOUSE
NC score	0.068996 (rank : 203)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	189	Target Neighborhood Hits	1278	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DESP_HUMAN
NC score	0.068680 (rank : 204)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	189	Target Neighborhood Hits	1470	Shared Neighborhood Hits	94
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

HOOK3_MOUSE
NC score	0.068614 (rank : 205)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	189	Target Neighborhood Hits	1007	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

TUFT1_MOUSE
NC score	0.068582 (rank : 206)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	189	Target Neighborhood Hits	732	Shared Neighborhood Hits	81
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

CR034_MOUSE
NC score	0.068554 (rank : 207)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	189	Target Neighborhood Hits	643	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

BICD1_MOUSE
NC score	0.068371 (rank : 208)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	189	Target Neighborhood Hits	837	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CK5P2_HUMAN
NC score	0.068147 (rank : 209)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	189	Target Neighborhood Hits	1433	Shared Neighborhood Hits	92
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CN145_MOUSE
NC score	0.068062 (rank : 210)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	189	Target Neighborhood Hits	916	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CT2NL_HUMAN
NC score	0.068047 (rank : 211)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	189	Target Neighborhood Hits	1059	Shared Neighborhood Hits	86
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

STAC_HUMAN
NC score	0.067960 (rank : 212)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	189	Target Neighborhood Hits	276	Shared Neighborhood Hits	47
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CK5P2_MOUSE
NC score	0.067902 (rank : 213)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	189	Target Neighborhood Hits	1151	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

GOGA1_MOUSE
NC score	0.067753 (rank : 214)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	189	Target Neighborhood Hits	994	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

CI039_HUMAN
NC score	0.067646 (rank : 215)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	189	Target Neighborhood Hits	1171	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

NIN_MOUSE
NC score	0.067503 (rank : 216)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	189	Target Neighborhood Hits	1376	Shared Neighborhood Hits	91
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

ITSN2_HUMAN
NC score	0.067448 (rank : 217)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	189	Target Neighborhood Hits	1173	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

RABE1_MOUSE
NC score	0.067447 (rank : 218)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	189	Target Neighborhood Hits	1105	Shared Neighborhood Hits	86
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

C102B_HUMAN
NC score	0.067248 (rank : 219)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	189	Target Neighborhood Hits	542	Shared Neighborhood Hits	70
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

GOGA3_MOUSE
NC score	0.067078 (rank : 220)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	189	Target Neighborhood Hits	1437	Shared Neighborhood Hits	90
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

K0555_HUMAN
NC score	0.067058 (rank : 221)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	189	Target Neighborhood Hits	880	Shared Neighborhood Hits	83
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

KTN1_MOUSE
NC score	0.066863 (rank : 222)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	189	Target Neighborhood Hits	1324	Shared Neighborhood Hits	86
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

SAS6_MOUSE
NC score	0.066796 (rank : 223)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	189	Target Neighborhood Hits	931	Shared Neighborhood Hits	85
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

TRIPB_HUMAN
NC score	0.066754 (rank : 224)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	189	Target Neighborhood Hits	1587	Shared Neighborhood Hits	95
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

AKAP9_HUMAN
NC score	0.066753 (rank : 225)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	189	Target Neighborhood Hits	1710	Shared Neighborhood Hits	96
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

GOGA5_MOUSE
NC score	0.066747 (rank : 226)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	189	Target Neighborhood Hits	1434	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

SAS6_HUMAN
NC score	0.066687 (rank : 227)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	189	Target Neighborhood Hits	791	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

DGKD_HUMAN
NC score	0.066558 (rank : 228)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	189	Target Neighborhood Hits	231	Shared Neighborhood Hits	51
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

CEP57_MOUSE
NC score	0.066385 (rank : 229)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	189	Target Neighborhood Hits	580	Shared Neighborhood Hits	77
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

TCRG1_MOUSE
NC score	0.066079 (rank : 230)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	189	Target Neighborhood Hits	947	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
NC score	0.065980 (rank : 231)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	189	Target Neighborhood Hits	929	Shared Neighborhood Hits	74
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

BICD1_HUMAN
NC score	0.065834 (rank : 232)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	189	Target Neighborhood Hits	844	Shared Neighborhood Hits	83
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

GOGA4_MOUSE
NC score	0.065794 (rank : 233)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	189	Target Neighborhood Hits	1939	Shared Neighborhood Hits	96
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_HUMAN
NC score	0.065793 (rank : 234)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	189	Target Neighborhood Hits	1168	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

IFT74_HUMAN
NC score	0.065670 (rank : 235)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	189	Target Neighborhood Hits	949	Shared Neighborhood Hits	85
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
NC score	0.065437 (rank : 236)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	189	Target Neighborhood Hits	893	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

GOGA1_HUMAN
NC score	0.065352 (rank : 237)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	189	Target Neighborhood Hits	1222	Shared Neighborhood Hits	89
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

AZI1_MOUSE
NC score	0.065305 (rank : 238)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	189	Target Neighborhood Hits	990	Shared Neighborhood Hits	85
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

IFT74_MOUSE
NC score	0.065303 (rank : 239)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	189	Target Neighborhood Hits	939	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

ANR26_MOUSE
NC score	0.065283 (rank : 240)	θ value	0.0193708 (rank : 65)
Query Neighborhood Hits	189	Target Neighborhood Hits	1554	Shared Neighborhood Hits	92
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GAS8_MOUSE
NC score	0.065244 (rank : 241)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	189	Target Neighborhood Hits	622	Shared Neighborhood Hits	80
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

FLIP1_MOUSE
NC score	0.065099 (rank : 242)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	189	Target Neighborhood Hits	1176	Shared Neighborhood Hits	85
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

SDCG8_HUMAN
NC score	0.065005 (rank : 243)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	189	Target Neighborhood Hits	1002	Shared Neighborhood Hits	81
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

NDE1_HUMAN
NC score	0.064996 (rank : 244)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	189	Target Neighborhood Hits	823	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

EEA1_HUMAN
NC score	0.064876 (rank : 245)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	189	Target Neighborhood Hits	1796	Shared Neighborhood Hits	93
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

SDCG8_MOUSE
NC score	0.064861 (rank : 246)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	189	Target Neighborhood Hits	886	Shared Neighborhood Hits	81
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CCD21_HUMAN
NC score	0.064777 (rank : 247)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	189	Target Neighborhood Hits	1228	Shared Neighborhood Hits	81
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

GRAP1_MOUSE
NC score	0.064732 (rank : 248)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	189	Target Neighborhood Hits	1234	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

CEP55_MOUSE
NC score	0.064677 (rank : 249)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	189	Target Neighborhood Hits	693	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CP250_MOUSE
NC score	0.064659 (rank : 250)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	189	Target Neighborhood Hits	1583	Shared Neighborhood Hits	94
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

KTN1_HUMAN
NC score	0.064445 (rank : 251)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	189	Target Neighborhood Hits	1197	Shared Neighborhood Hits	88
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

NEMO_HUMAN
NC score	0.064402 (rank : 252)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	189	Target Neighborhood Hits	820	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

CYTSA_MOUSE
NC score	0.064324 (rank : 253)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	189	Target Neighborhood Hits	1104	Shared Neighborhood Hits	87
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

GOGA3_HUMAN
NC score	0.064299 (rank : 254)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	189	Target Neighborhood Hits	1317	Shared Neighborhood Hits	89
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

BICD2_HUMAN
NC score	0.064081 (rank : 255)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	189	Target Neighborhood Hits	856	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BPAEA_MOUSE
NC score	0.063869 (rank : 256)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	189	Target Neighborhood Hits	1480	Shared Neighborhood Hits	92
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CEP55_HUMAN
NC score	0.063832 (rank : 257)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	189	Target Neighborhood Hits	504	Shared Neighborhood Hits	74
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP57_HUMAN
NC score	0.063745 (rank : 258)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	189	Target Neighborhood Hits	576	Shared Neighborhood Hits	77
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

BICD2_MOUSE
NC score	0.063551 (rank : 259)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	189	Target Neighborhood Hits	864	Shared Neighborhood Hits	85
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

GOGA6_HUMAN
NC score	0.063415 (rank : 260)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	189	Target Neighborhood Hits	1007	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

LIPA1_HUMAN
NC score	0.063411 (rank : 261)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	189	Target Neighborhood Hits	1294	Shared Neighborhood Hits	89
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

CKAP4_HUMAN
NC score	0.063375 (rank : 262)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	189	Target Neighborhood Hits	592	Shared Neighborhood Hits	71
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

GOGA2_MOUSE
NC score	0.063356 (rank : 263)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	189	Target Neighborhood Hits	944	Shared Neighborhood Hits	85
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

CYTSA_HUMAN
NC score	0.063282 (rank : 264)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	189	Target Neighborhood Hits	1138	Shared Neighborhood Hits	85
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

AMOL1_HUMAN
NC score	0.063205 (rank : 265)	θ value	0.365318 (rank : 92)
Query Neighborhood Hits	189	Target Neighborhood Hits	435	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

CCD41_MOUSE
NC score	0.063142 (rank : 266)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	189	Target Neighborhood Hits	1399	Shared Neighborhood Hits	85
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

AZI1_HUMAN
NC score	0.063052 (rank : 267)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	189	Target Neighborhood Hits	1000	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CCHCR_MOUSE
NC score	0.063019 (rank : 268)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	189	Target Neighborhood Hits	932	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

LRC45_HUMAN
NC score	0.063011 (rank : 269)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	189	Target Neighborhood Hits	933	Shared Neighborhood Hits	87
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

KNTC2_HUMAN
NC score	0.062953 (rank : 270)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	189	Target Neighborhood Hits	673	Shared Neighborhood Hits	77
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

CF060_HUMAN
NC score	0.062815 (rank : 271)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	189	Target Neighborhood Hits	1270	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

3BP5_HUMAN
NC score	0.062807 (rank : 272)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	189	Target Neighborhood Hits	375	Shared Neighborhood Hits	67
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

MRCKB_MOUSE
NC score	0.062673 (rank : 273)	θ value	0.0961366 (rank : 77)
Query Neighborhood Hits	189	Target Neighborhood Hits	2180	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CENPE_HUMAN
NC score	0.062661 (rank : 274)	θ value	0.279714 (rank : 88)
Query Neighborhood Hits	189	Target Neighborhood Hits	2060	Shared Neighborhood Hits	99
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

LIPA2_MOUSE
NC score	0.062608 (rank : 275)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	189	Target Neighborhood Hits	1282	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MIPO1_HUMAN
NC score	0.062544 (rank : 276)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	189	Target Neighborhood Hits	486	Shared Neighborhood Hits	70
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

SM1L2_HUMAN
NC score	0.062491 (rank : 277)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	189	Target Neighborhood Hits	1019	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC4_HUMAN
NC score	0.062490 (rank : 278)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	189	Target Neighborhood Hits	937	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

RRBP1_HUMAN
NC score	0.062411 (rank : 279)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	189	Target Neighborhood Hits	1306	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

MRCKA_HUMAN
NC score	0.062381 (rank : 280)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	189	Target Neighborhood Hits	1999	Shared Neighborhood Hits	127
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

T3JAM_HUMAN
NC score	0.062366 (rank : 281)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	189	Target Neighborhood Hits	533	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

3BP5_MOUSE
NC score	0.062241 (rank : 282)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	189	Target Neighborhood Hits	346	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

CF152_HUMAN
NC score	0.062079 (rank : 283)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	189	Target Neighborhood Hits	704	Shared Neighborhood Hits	80
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

TSC1_HUMAN
NC score	0.061994 (rank : 284)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	189	Target Neighborhood Hits	765	Shared Neighborhood Hits	72
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

EEA1_MOUSE
NC score	0.061933 (rank : 285)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	189	Target Neighborhood Hits	1637	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GAS8_HUMAN
NC score	0.061927 (rank : 286)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	189	Target Neighborhood Hits	819	Shared Neighborhood Hits	81
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

RFIP3_HUMAN
NC score	0.061923 (rank : 287)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	189	Target Neighborhood Hits	1055	Shared Neighborhood Hits	88
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

CKAP4_MOUSE
NC score	0.061744 (rank : 288)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	189	Target Neighborhood Hits	596	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

VAV2_HUMAN
NC score	0.061696 (rank : 289)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	189	Target Neighborhood Hits	453	Shared Neighborhood Hits	51
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

CCD21_MOUSE
NC score	0.061682 (rank : 290)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	189	Target Neighborhood Hits	1135	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CALD1_HUMAN
NC score	0.061653 (rank : 291)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	189	Target Neighborhood Hits	959	Shared Neighborhood Hits	74
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

MD1L1_MOUSE
NC score	0.061597 (rank : 292)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	189	Target Neighborhood Hits	1001	Shared Neighborhood Hits	84
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

HMMR_HUMAN
NC score	0.061517 (rank : 293)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	189	Target Neighborhood Hits	1082	Shared Neighborhood Hits	83
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

OPTN_HUMAN
NC score	0.061511 (rank : 294)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	189	Target Neighborhood Hits	827	Shared Neighborhood Hits	76
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

TEX9_MOUSE
NC score	0.061438 (rank : 295)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	189	Target Neighborhood Hits	581	Shared Neighborhood Hits	78
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

DGKB_HUMAN
NC score	0.061409 (rank : 296)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	189	Target Neighborhood Hits	238	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

SMC1A_MOUSE
NC score	0.061329 (rank : 297)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	189	Target Neighborhood Hits	1384	Shared Neighborhood Hits	88
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

NUMA1_HUMAN
NC score	0.061158 (rank : 298)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	189	Target Neighborhood Hits	1523	Shared Neighborhood Hits	87
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

KMHN1_MOUSE
NC score	0.061062 (rank : 299)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	189	Target Neighborhood Hits	949	Shared Neighborhood Hits	82
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

VAV2_MOUSE
NC score	0.061016 (rank : 300)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	189	Target Neighborhood Hits	456	Shared Neighborhood Hits	46
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

CCD96_HUMAN
NC score	0.060998 (rank : 301)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	189	Target Neighborhood Hits	595	Shared Neighborhood Hits	68
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

LRC45_MOUSE
NC score	0.060974 (rank : 302)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	189	Target Neighborhood Hits	959	Shared Neighborhood Hits	78
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

PCNT_HUMAN
NC score	0.060888 (rank : 303)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	189	Target Neighborhood Hits	1551	Shared Neighborhood Hits	91
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CTGE5_MOUSE
NC score	0.060866 (rank : 304)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	189	Target Neighborhood Hits	928	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

NCK2_HUMAN
NC score	0.060756 (rank : 305)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	189	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

ANR26_HUMAN
NC score	0.060519 (rank : 306)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	189	Target Neighborhood Hits	1614	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

POF1B_MOUSE
NC score	0.060469 (rank : 307)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	189	Target Neighborhood Hits	530	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

SWP70_MOUSE
NC score	0.060435 (rank : 308)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	189	Target Neighborhood Hits	1097	Shared Neighborhood Hits	84
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

DYNA_HUMAN
NC score	0.060410 (rank : 309)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	189	Target Neighborhood Hits	1194	Shared Neighborhood Hits	84
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

NUF2_HUMAN
NC score	0.060409 (rank : 310)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	189	Target Neighborhood Hits	661	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

DDEF2_HUMAN
NC score	0.060255 (rank : 311)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	189	Target Neighborhood Hits	599	Shared Neighborhood Hits	25
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CTRO_MOUSE
NC score	0.060229 (rank : 312)	θ value	0.0148317 (rank : 64)
Query Neighborhood Hits	189	Target Neighborhood Hits	2344	Shared Neighborhood Hits	124
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DYNA_MOUSE
NC score	0.060208 (rank : 313)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	189	Target Neighborhood Hits	1084	Shared Neighborhood Hits	84
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

SMC3_MOUSE
NC score	0.060192 (rank : 314)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	189	Target Neighborhood Hits	1187	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC1A_HUMAN
NC score	0.060134 (rank : 315)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	189	Target Neighborhood Hits	1346	Shared Neighborhood Hits	86
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

CAR11_HUMAN
NC score	0.060067 (rank : 316)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	189	Target Neighborhood Hits	690	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

TRAK1_HUMAN
NC score	0.059986 (rank : 317)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	189	Target Neighborhood Hits	660	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

TNIP3_HUMAN
NC score	0.059921 (rank : 318)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	189	Target Neighborhood Hits	511	Shared Neighborhood Hits	72
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

MRCKB_HUMAN
NC score	0.059848 (rank : 319)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	189	Target Neighborhood Hits	2239	Shared Neighborhood Hits	126
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RBCC1_MOUSE
NC score	0.059846 (rank : 320)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	189	Target Neighborhood Hits	1048	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

PEPL_HUMAN
NC score	0.059827 (rank : 321)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	189	Target Neighborhood Hits	1141	Shared Neighborhood Hits	84
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

CCHCR_HUMAN
NC score	0.059752 (rank : 322)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	189	Target Neighborhood Hits	717	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

SMC3_HUMAN
NC score	0.059742 (rank : 323)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	189	Target Neighborhood Hits	1186	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

CRCM_HUMAN
NC score	0.059435 (rank : 324)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	189	Target Neighborhood Hits	520	Shared Neighborhood Hits	72
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

MD1L1_HUMAN
NC score	0.059364 (rank : 325)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	189	Target Neighborhood Hits	893	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CF152_MOUSE
NC score	0.059296 (rank : 326)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	189	Target Neighborhood Hits	597	Shared Neighborhood Hits	70
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

TRAIP_MOUSE
NC score	0.059245 (rank : 327)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	189	Target Neighborhood Hits	745	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

RIMB1_MOUSE
NC score	0.059102 (rank : 328)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	189	Target Neighborhood Hits	1376	Shared Neighborhood Hits	92
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

GRAP_HUMAN
NC score	0.059094 (rank : 329)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	189	Target Neighborhood Hits	307	Shared Neighborhood Hits	19
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

TRAIP_HUMAN
NC score	0.059076 (rank : 330)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	189	Target Neighborhood Hits	780	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

SPTA2_HUMAN
NC score	0.058971 (rank : 331)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	189	Target Neighborhood Hits	888	Shared Neighborhood Hits	86
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

DP13A_HUMAN
NC score	0.058950 (rank : 332)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	189	Target Neighborhood Hits	107	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

CCD41_HUMAN
NC score	0.058947 (rank : 333)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	189	Target Neighborhood Hits	1139	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

LIPA2_HUMAN
NC score	0.058930 (rank : 334)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	189	Target Neighborhood Hits	1044	Shared Neighborhood Hits	86
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

UACA_MOUSE
NC score	0.058818 (rank : 335)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	189	Target Neighborhood Hits	1620	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

IFT81_MOUSE
NC score	0.058803 (rank : 336)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	189	Target Neighborhood Hits	959	Shared Neighborhood Hits	79
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

AMOL1_MOUSE
NC score	0.058630 (rank : 337)	θ value	1.06291 (rank : 114)
Query Neighborhood Hits	189	Target Neighborhood Hits	445	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

TACC3_HUMAN
NC score	0.058584 (rank : 338)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	189	Target Neighborhood Hits	779	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

SWP70_HUMAN
NC score	0.058553 (rank : 339)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	189	Target Neighborhood Hits	973	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TMF1_HUMAN
NC score	0.058541 (rank : 340)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	189	Target Neighborhood Hits	987	Shared Neighborhood Hits	77
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

SYNE1_HUMAN
NC score	0.058515 (rank : 341)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	189	Target Neighborhood Hits	1484	Shared Neighborhood Hits	95
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

GRAP1_HUMAN
NC score	0.058472 (rank : 342)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	189	Target Neighborhood Hits	944	Shared Neighborhood Hits	85
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

PKHA1_HUMAN
NC score	0.058464 (rank : 343)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	189	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

EP15R_HUMAN
NC score	0.058410 (rank : 344)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	189	Target Neighborhood Hits	1083	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

HOME2_MOUSE
NC score	0.058394 (rank : 345)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	189	Target Neighborhood Hits	882	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

DDEF2_MOUSE
NC score	0.058312 (rank : 346)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	189	Target Neighborhood Hits	625	Shared Neighborhood Hits	20
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TUFT1_HUMAN
NC score	0.058272 (rank : 347)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	189	Target Neighborhood Hits	686	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

FA13C_HUMAN
NC score	0.058259 (rank : 348)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	189	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

BRE1A_MOUSE
NC score	0.058207 (rank : 349)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	189	Target Neighborhood Hits	1025	Shared Neighborhood Hits	85
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CUTL2_HUMAN
NC score	0.058097 (rank : 350)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	189	Target Neighborhood Hits	906	Shared Neighborhood Hits	69
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CDR2_MOUSE
NC score	0.058066 (rank : 351)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	189	Target Neighborhood Hits	482	Shared Neighborhood Hits	72
SwissProt Accessions	P97817	Gene names	Cdr2
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2.

EVPL_HUMAN
NC score	0.057789 (rank : 352)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	189	Target Neighborhood Hits	895	Shared Neighborhood Hits	84
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

CCD93_HUMAN
NC score	0.057785 (rank : 353)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	189	Target Neighborhood Hits	600	Shared Neighborhood Hits	67
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

LUZP1_MOUSE
NC score	0.057772 (rank : 354)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	189	Target Neighborhood Hits	940	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

UACA_HUMAN
NC score	0.057628 (rank : 355)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	189	Target Neighborhood Hits	1622	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

SPTA1_HUMAN
NC score	0.057502 (rank : 356)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	189	Target Neighborhood Hits	748	Shared Neighborhood Hits	84
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CARD9_HUMAN
NC score	0.057488 (rank : 357)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	189	Target Neighborhood Hits	602	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

HIP1_HUMAN
NC score	0.057378 (rank : 358)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	189	Target Neighborhood Hits	1016	Shared Neighborhood Hits	80
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

DAPP1_MOUSE
NC score	0.057261 (rank : 359)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	189	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

BRE1A_HUMAN
NC score	0.057181 (rank : 360)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	189	Target Neighborhood Hits	1071	Shared Neighborhood Hits	82
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

DLG5_HUMAN
NC score	0.057075 (rank : 361)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	189	Target Neighborhood Hits	1088	Shared Neighborhood Hits	84
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

CNTRB_MOUSE
NC score	0.057064 (rank : 362)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	189	Target Neighborhood Hits	1029	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

RUFY2_HUMAN
NC score	0.057064 (rank : 363)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	189	Target Neighborhood Hits	1208	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

POF1B_HUMAN
NC score	0.057048 (rank : 364)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	189	Target Neighborhood Hits	494	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

HAP1_HUMAN
NC score	0.057041 (rank : 365)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	189	Target Neighborhood Hits	606	Shared Neighborhood Hits	74
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

PEPL_MOUSE
NC score	0.057007 (rank : 366)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	189	Target Neighborhood Hits	1105	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

DDFL1_HUMAN
NC score	0.056961 (rank : 367)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	189	Target Neighborhood Hits	353	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

MPP9_HUMAN
NC score	0.056903 (rank : 368)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	189	Target Neighborhood Hits	529	Shared Neighborhood Hits	69
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

FA13C_MOUSE
NC score	0.056753 (rank : 369)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	189	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

HIP1R_MOUSE
NC score	0.056663 (rank : 370)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	189	Target Neighborhood Hits	959	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

TACC3_MOUSE
NC score	0.056609 (rank : 371)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	189	Target Neighborhood Hits	607	Shared Neighborhood Hits	73
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

KNTC2_MOUSE
NC score	0.056565 (rank : 372)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	189	Target Neighborhood Hits	692	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

EP15R_MOUSE
NC score	0.056442 (rank : 373)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	189	Target Neighborhood Hits	1135	Shared Neighborhood Hits	86
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

NDE1_MOUSE
NC score	0.056369 (rank : 374)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	189	Target Neighborhood Hits	602	Shared Neighborhood Hits	74
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

GRAP_MOUSE
NC score	0.056361 (rank : 375)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	189	Target Neighborhood Hits	309	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

CCDC6_HUMAN
NC score	0.056294 (rank : 376)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	189	Target Neighborhood Hits	723	Shared Neighborhood Hits	77
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

RABE2_MOUSE
NC score	0.056276 (rank : 377)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	189	Target Neighborhood Hits	598	Shared Neighborhood Hits	80
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

HOOK1_MOUSE
NC score	0.056203 (rank : 378)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	189	Target Neighborhood Hits	910	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

CEP70_HUMAN
NC score	0.056151 (rank : 379)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	189	Target Neighborhood Hits	432	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

PHLB2_HUMAN
NC score	0.056124 (rank : 380)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	189	Target Neighborhood Hits	964	Shared Neighborhood Hits	81
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

CTRO_HUMAN
NC score	0.055935 (rank : 381)	θ value	0.0148317 (rank : 63)
Query Neighborhood Hits	189	Target Neighborhood Hits	2092	Shared Neighborhood Hits	121
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CT2NL_MOUSE
NC score	0.055907 (rank : 382)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	189	Target Neighborhood Hits	902	Shared Neighborhood Hits	83
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RBCC1_HUMAN
NC score	0.055873 (rank : 383)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	189	Target Neighborhood Hits	1023	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

LUZP1_HUMAN
NC score	0.055866 (rank : 384)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	189	Target Neighborhood Hits	739	Shared Neighborhood Hits	77
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

GRB2_HUMAN
NC score	0.055820 (rank : 385)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	189	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.055812 (rank : 386)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	189	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

TRHY_HUMAN
NC score	0.055730 (rank : 387)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	189	Target Neighborhood Hits	1385	Shared Neighborhood Hits	81
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CTGE6_HUMAN
NC score	0.055721 (rank : 388)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	189	Target Neighborhood Hits	650	Shared Neighborhood Hits	76
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

DAPP1_HUMAN
NC score	0.055689 (rank : 389)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	189	Target Neighborhood Hits	227	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PCNT_MOUSE
NC score	0.055652 (rank : 390)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	189	Target Neighborhood Hits	1207	Shared Neighborhood Hits	81
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

CENA2_HUMAN
NC score	0.055633 (rank : 391)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

NAF1_HUMAN
NC score	0.055604 (rank : 392)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	189	Target Neighborhood Hits	937	Shared Neighborhood Hits	81
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

FYCO1_HUMAN
NC score	0.055540 (rank : 393)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	189	Target Neighborhood Hits	1149	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

TACC2_HUMAN
NC score	0.055452 (rank : 394)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	189	Target Neighborhood Hits	856	Shared Neighborhood Hits	81
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

SPTA1_MOUSE
NC score	0.055441 (rank : 395)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	189	Target Neighborhood Hits	675	Shared Neighborhood Hits	83
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

RRBP1_MOUSE
NC score	0.055418 (rank : 396)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	189	Target Neighborhood Hits	1650	Shared Neighborhood Hits	89
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

IF3A_HUMAN
NC score	0.055398 (rank : 397)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	189	Target Neighborhood Hits	875	Shared Neighborhood Hits	78
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

BRE1B_MOUSE
NC score	0.055292 (rank : 398)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	189	Target Neighborhood Hits	970	Shared Neighborhood Hits	78
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.055288 (rank : 399)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	189	Target Neighborhood Hits	1040	Shared Neighborhood Hits	79
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

FYCO1_MOUSE
NC score	0.055246 (rank : 400)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	189	Target Neighborhood Hits	1059	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

CCD96_MOUSE
NC score	0.055241 (rank : 401)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	189	Target Neighborhood Hits	704	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

IF3A_MOUSE
NC score	0.055186 (rank : 402)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	189	Target Neighborhood Hits	871	Shared Neighborhood Hits	79
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

SPAG5_MOUSE
NC score	0.055080 (rank : 403)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	189	Target Neighborhood Hits	612	Shared Neighborhood Hits	70
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

DDEF1_MOUSE
NC score	0.055054 (rank : 404)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	189	Target Neighborhood Hits	592	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

SMP1L_HUMAN
NC score	0.054993 (rank : 405)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	189	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

MRIP_HUMAN
NC score	0.054971 (rank : 406)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	189	Target Neighborhood Hits	578	Shared Neighborhood Hits	72
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

SMP1L_MOUSE
NC score	0.054969 (rank : 407)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	189	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

CR034_HUMAN
NC score	0.054888 (rank : 408)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	189	Target Neighborhood Hits	538	Shared Neighborhood Hits	74
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

YO11_MOUSE
NC score	0.054815 (rank : 409)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	189	Target Neighborhood Hits	272	Shared Neighborhood Hits	56
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

OFD1_HUMAN
NC score	0.054806 (rank : 410)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	189	Target Neighborhood Hits	753	Shared Neighborhood Hits	78
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

CTGE5_HUMAN
NC score	0.054775 (rank : 411)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	189	Target Neighborhood Hits	800	Shared Neighborhood Hits	77
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

VAV_MOUSE
NC score	0.054729 (rank : 412)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	189	Target Neighborhood Hits	430	Shared Neighborhood Hits	49
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

GCC1_HUMAN
NC score	0.054668 (rank : 413)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	189	Target Neighborhood Hits	887	Shared Neighborhood Hits	77
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

SPC24_HUMAN
NC score	0.054619 (rank : 414)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	189	Target Neighborhood Hits	324	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

SPAG5_HUMAN
NC score	0.054575 (rank : 415)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	189	Target Neighborhood Hits	625	Shared Neighborhood Hits	71
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

MRIP_MOUSE
NC score	0.054538 (rank : 416)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	189	Target Neighborhood Hits	569	Shared Neighborhood Hits	69
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

TACC2_MOUSE
NC score	0.054516 (rank : 417)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	189	Target Neighborhood Hits	774	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

MACOI_MOUSE
NC score	0.054452 (rank : 418)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	189	Target Neighborhood Hits	620	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

PCTL_MOUSE
NC score	0.054394 (rank : 419)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	189	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

NAF1_MOUSE
NC score	0.054378 (rank : 420)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	189	Target Neighborhood Hits	852	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

UTRO_HUMAN
NC score	0.054220 (rank : 421)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	189	Target Neighborhood Hits	960	Shared Neighborhood Hits	82
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

GOGA2_HUMAN
NC score	0.054146 (rank : 422)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	189	Target Neighborhood Hits	856	Shared Neighborhood Hits	79
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

LIPB1_MOUSE
NC score	0.054061 (rank : 423)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	189	Target Neighborhood Hits	727	Shared Neighborhood Hits	78
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

DP13A_MOUSE
NC score	0.053988 (rank : 424)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	189	Target Neighborhood Hits	96	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

MACOI_HUMAN
NC score	0.053964 (rank : 425)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	189	Target Neighborhood Hits	650	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

RFIP4_HUMAN
NC score	0.053854 (rank : 426)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	189	Target Neighborhood Hits	785	Shared Neighborhood Hits	79
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

PCTL_HUMAN
NC score	0.053819 (rank : 427)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	189	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

ROCK1_MOUSE
NC score	0.053711 (rank : 428)	θ value	0.279714 (rank : 89)
Query Neighborhood Hits	189	Target Neighborhood Hits	2126	Shared Neighborhood Hits	118
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

RUFY3_HUMAN
NC score	0.053553 (rank : 429)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	189	Target Neighborhood Hits	594	Shared Neighborhood Hits	75
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

SMAP1_MOUSE
NC score	0.053401 (rank : 430)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	189	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

HOOK1_HUMAN
NC score	0.053382 (rank : 431)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	189	Target Neighborhood Hits	942	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

EVPL_MOUSE
NC score	0.053356 (rank : 432)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	189	Target Neighborhood Hits	952	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

PHLB2_MOUSE
NC score	0.053347 (rank : 433)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	189	Target Neighborhood Hits	1016	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SMAP1_HUMAN
NC score	0.053318 (rank : 434)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	189	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

BPA1_MOUSE
NC score	0.053120 (rank : 435)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	189	Target Neighborhood Hits	1477	Shared Neighborhood Hits	89
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PKHA1_MOUSE
NC score	0.053035 (rank : 436)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	189	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

HIP1R_HUMAN
NC score	0.052932 (rank : 437)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	189	Target Neighborhood Hits	809	Shared Neighborhood Hits	81
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

INVO_HUMAN
NC score	0.052859 (rank : 438)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	189	Target Neighborhood Hits	636	Shared Neighborhood Hits	64
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

RIMB1_HUMAN
NC score	0.052831 (rank : 439)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	189	Target Neighborhood Hits	1479	Shared Neighborhood Hits	83
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

VAV_HUMAN
NC score	0.052765 (rank : 440)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	189	Target Neighborhood Hits	452	Shared Neighborhood Hits	54
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

RFIP4_MOUSE
NC score	0.052760 (rank : 441)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	189	Target Neighborhood Hits	708	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RUFY3_MOUSE
NC score	0.052721 (rank : 442)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	189	Target Neighborhood Hits	579	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D394, Q3U348, Q3UF96, Q6PE64, Q8VD10	Gene names	Rufy3, D5Bwg0860e, Ripx
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

CENA1_HUMAN
NC score	0.052520 (rank : 443)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

ADIP_HUMAN
NC score	0.052453 (rank : 444)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	189	Target Neighborhood Hits	470	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

CNTRB_HUMAN
NC score	0.052180 (rank : 445)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	189	Target Neighborhood Hits	690	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

SPTB2_MOUSE
NC score	0.052168 (rank : 446)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	189	Target Neighborhood Hits	770	Shared Neighborhood Hits	80
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

CCD42_HUMAN
NC score	0.052053 (rank : 447)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	189	Target Neighborhood Hits	406	Shared Neighborhood Hits	65
SwissProt Accessions	Q96M95, Q8N6Q0	Gene names	CCDC42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

CCD11_MOUSE
NC score	0.052002 (rank : 448)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	189	Target Neighborhood Hits	498	Shared Neighborhood Hits	64
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

ROCK1_HUMAN
NC score	0.052000 (rank : 449)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	189	Target Neighborhood Hits	2000	Shared Neighborhood Hits	115
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SMC4_MOUSE
NC score	0.051863 (rank : 450)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	189	Target Neighborhood Hits	830	Shared Neighborhood Hits	77
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

XE7_HUMAN
NC score	0.051862 (rank : 451)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	189	Target Neighborhood Hits	738	Shared Neighborhood Hits	71
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

CEP70_MOUSE
NC score	0.051758 (rank : 452)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	189	Target Neighborhood Hits	532	Shared Neighborhood Hits	72
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

INCE_MOUSE
NC score	0.051612 (rank : 453)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	189	Target Neighborhood Hits	903	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

AMOL2_MOUSE
NC score	0.051571 (rank : 454)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	189	Target Neighborhood Hits	591	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

CT096_HUMAN
NC score	0.051535 (rank : 455)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	189	Target Neighborhood Hits	438	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

KINH_HUMAN
NC score	0.051498 (rank : 456)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	189	Target Neighborhood Hits	1231	Shared Neighborhood Hits	89
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

HC127_HUMAN
NC score	0.051487 (rank : 457)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	189	Target Neighborhood Hits	292	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
NC score	0.051487 (rank : 458)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	189	Target Neighborhood Hits	292	Shared Neighborhood Hits	54
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

EP15_HUMAN
NC score	0.051470 (rank : 459)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	189	Target Neighborhood Hits	1021	Shared Neighborhood Hits	82
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

AMOT_HUMAN
NC score	0.051261 (rank : 460)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	189	Target Neighborhood Hits	712	Shared Neighborhood Hits	67
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CU013_HUMAN
NC score	0.051259 (rank : 461)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	189	Target Neighborhood Hits	405	Shared Neighborhood Hits	63
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

GCC1_MOUSE
NC score	0.051227 (rank : 462)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	189	Target Neighborhood Hits	777	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

DMD_MOUSE
NC score	0.051027 (rank : 463)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	189	Target Neighborhood Hits	1111	Shared Neighborhood Hits	83
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

RUFY2_MOUSE
NC score	0.050877 (rank : 464)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	189	Target Neighborhood Hits	820	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

CCD91_MOUSE
NC score	0.050852 (rank : 465)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	189	Target Neighborhood Hits	699	Shared Neighborhood Hits	71
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

NEMO_MOUSE
NC score	0.050821 (rank : 466)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	189	Target Neighborhood Hits	658	Shared Neighborhood Hits	67
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

LRRF1_HUMAN
NC score	0.050774 (rank : 467)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	189	Target Neighborhood Hits	625	Shared Neighborhood Hits	67
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

SPTB2_HUMAN
NC score	0.050709 (rank : 468)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	189	Target Neighborhood Hits	748	Shared Neighborhood Hits	81
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

AMOL2_HUMAN
NC score	0.050699 (rank : 469)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	189	Target Neighborhood Hits	603	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

BNIP2_HUMAN
NC score	0.050654 (rank : 470)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	189	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
NC score	0.050556 (rank : 471)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	189	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

CUTL2_MOUSE
NC score	0.050513 (rank : 472)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	189	Target Neighborhood Hits	771	Shared Neighborhood Hits	64
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CF182_MOUSE
NC score	0.050460 (rank : 473)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	189	Target Neighborhood Hits	551	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

RPGR1_HUMAN
NC score	0.050439 (rank : 474)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	189	Target Neighborhood Hits	578	Shared Neighborhood Hits	66
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CCD19_HUMAN
NC score	0.050257 (rank : 475)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	189	Target Neighborhood Hits	639	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD11_HUMAN
NC score	0.050235 (rank : 476)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	189	Target Neighborhood Hits	822	Shared Neighborhood Hits	75
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

INCE_HUMAN
NC score	0.050181 (rank : 477)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	189	Target Neighborhood Hits	978	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MACF1_MOUSE
NC score	0.050116 (rank : 478)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	189	Target Neighborhood Hits	1313	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

HOOK2_HUMAN
NC score	0.050073 (rank : 479)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	189	Target Neighborhood Hits	714	Shared Neighborhood Hits	76
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

ARFG3_MOUSE
NC score	0.050019 (rank : 480)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	189	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

PLEC1_HUMAN
NC score	0.049404 (rank : 481)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	189	Target Neighborhood Hits	1326	Shared Neighborhood Hits	82
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

KPCD3_HUMAN
NC score	0.048735 (rank : 482)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	189	Target Neighborhood Hits	895	Shared Neighborhood Hits	49
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

KPCD1_HUMAN
NC score	0.048190 (rank : 483)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	189	Target Neighborhood Hits	901	Shared Neighborhood Hits	49
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD1_MOUSE
NC score	0.047897 (rank : 484)	θ value	0.0563607 (rank : 73)
Query Neighborhood Hits	189	Target Neighborhood Hits	891	Shared Neighborhood Hits	49
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD3_MOUSE
NC score	0.047764 (rank : 485)	θ value	0.21417 (rank : 85)
Query Neighborhood Hits	189	Target Neighborhood Hits	901	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

RADI_MOUSE
NC score	0.047633 (rank : 486)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	189	Target Neighborhood Hits	773	Shared Neighborhood Hits	78
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

KPCD2_HUMAN
NC score	0.046523 (rank : 487)	θ value	0.0563607 (rank : 74)
Query Neighborhood Hits	189	Target Neighborhood Hits	910	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

TFAP4_HUMAN
NC score	0.043892 (rank : 488)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	189	Target Neighborhood Hits	289	Shared Neighborhood Hits	42
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

SNX23_HUMAN
NC score	0.042941 (rank : 489)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	189	Target Neighborhood Hits	944	Shared Neighborhood Hits	80
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

DGKA_HUMAN
NC score	0.042730 (rank : 490)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	189	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

RADI_HUMAN
NC score	0.042537 (rank : 491)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	189	Target Neighborhood Hits	741	Shared Neighborhood Hits	74
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

KPCD_HUMAN
NC score	0.039182 (rank : 492)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	189	Target Neighborhood Hits	900	Shared Neighborhood Hits	49
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCD_MOUSE
NC score	0.038332 (rank : 493)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	189	Target Neighborhood Hits	888	Shared Neighborhood Hits	49
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCT_MOUSE
NC score	0.035356 (rank : 494)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	189	Target Neighborhood Hits	895	Shared Neighborhood Hits	46
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_HUMAN
NC score	0.035257 (rank : 495)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	189	Target Neighborhood Hits	897	Shared Neighborhood Hits	46
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCA_HUMAN
NC score	0.034421 (rank : 496)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	189	Target Neighborhood Hits	1070	Shared Neighborhood Hits	51
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
NC score	0.033539 (rank : 497)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	189	Target Neighborhood Hits	1067	Shared Neighborhood Hits	51
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

ATAD3_MOUSE
NC score	0.031054 (rank : 498)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	189	Target Neighborhood Hits	326	Shared Neighborhood Hits	48
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

KPCZ_HUMAN
NC score	0.030252 (rank : 499)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	189	Target Neighborhood Hits	884	Shared Neighborhood Hits	47
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KPCI_MOUSE
NC score	0.029544 (rank : 500)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	189	Target Neighborhood Hits	888	Shared Neighborhood Hits	49
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

KSR2_HUMAN
NC score	0.029325 (rank : 501)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	189	Target Neighborhood Hits	920	Shared Neighborhood Hits	44
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KPCI_HUMAN
NC score	0.029289 (rank : 502)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	189	Target Neighborhood Hits	885	Shared Neighborhood Hits	47
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

RAF1_HUMAN
NC score	0.024035 (rank : 503)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	189	Target Neighborhood Hits	886	Shared Neighborhood Hits	42
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

ARAF_MOUSE
NC score	0.023728 (rank : 504)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	189	Target Neighborhood Hits	874	Shared Neighborhood Hits	41
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

RAF1_MOUSE
NC score	0.023677 (rank : 505)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	189	Target Neighborhood Hits	886	Shared Neighborhood Hits	42
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

ARAF_HUMAN
NC score	0.023566 (rank : 506)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	189	Target Neighborhood Hits	924	Shared Neighborhood Hits	41
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

BRAF1_HUMAN
NC score	0.022065 (rank : 507)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	189	Target Neighborhood Hits	883	Shared Neighborhood Hits	42
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

ACTN4_MOUSE
NC score	0.021179 (rank : 508)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	189	Target Neighborhood Hits	276	Shared Neighborhood Hits	43
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_HUMAN
NC score	0.020492 (rank : 509)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	189	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

KSR1_HUMAN
NC score	0.020365 (rank : 510)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	189	Target Neighborhood Hits	867	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

NUCKS_HUMAN
NC score	0.017277 (rank : 511)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	189	Target Neighborhood Hits	143	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
NC score	0.014088 (rank : 512)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	189	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

DOK3_HUMAN
NC score	0.013612 (rank : 513)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	189	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

M3K10_HUMAN
NC score	0.013167 (rank : 514)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	189	Target Neighborhood Hits	1071	Shared Neighborhood Hits	50
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

RN123_MOUSE
NC score	0.012998 (rank : 515)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	189	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

SC11A_HUMAN
NC score	0.011338 (rank : 516)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	189	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

MYCS_MOUSE
NC score	0.010507 (rank : 517)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

AAKG3_HUMAN
NC score	0.010461 (rank : 518)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	189	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGI9, Q4QQG8, Q4V779, Q9NRL1	Gene names	PRKAG3, AMPKG3
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma-3 chain) (AMPK gamma3).

HRX_HUMAN
NC score	0.009917 (rank : 519)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	189	Target Neighborhood Hits	825	Shared Neighborhood Hits	13
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

WASF3_MOUSE
NC score	0.007655 (rank : 520)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	189	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

TIMD4_MOUSE
NC score	0.006806 (rank : 521)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	189	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q6U7R4, Q6U7R3, Q8CIC7	Gene names	Timd4, Tim4
Domain Architecture	No domain graphic available
Description	T-cell immunoglobulin and mucin domain-containing protein 4 precursor (TIMD-4) (T-cell membrane protein 4) (TIM-4) (Spleen, mucin- containing, knockout of lymphotoxin protein) (SMUCKLER).

SPY2_MOUSE
NC score	0.005994 (rank : 522)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	189	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

ZN213_HUMAN
NC score	-0.007540 (rank : 523)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	189	Target Neighborhood Hits	755	Shared Neighborhood Hits	2
SwissProt Accessions	O14771, Q96IS1	Gene names	ZNF213
Domain Architecture
Description	Zinc finger protein 213 (Putative transcription factor CR53).