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Network neighborhood for query Sequence : TCGAP_MOUSE

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TCGAP_MOUSE
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TCGAP_HUMAN
θ value	0 (rank : 1)	NC score	0.875877 (rank : 2)
Query Neighborhood Hits	409	Target Neighborhood Hits	872	Shared Neighborhood Hits	319
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	409	Target Neighborhood Hits	409	Shared Neighborhood Hits	409
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CHIN_HUMAN
θ value	1.52067e-31 (rank : 3)	NC score	0.745046 (rank : 16)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	83
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	4.42448e-31 (rank : 4)	NC score	0.745813 (rank : 15)
Query Neighborhood Hits	409	Target Neighborhood Hits	229	Shared Neighborhood Hits	86
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_MOUSE
θ value	2.86786e-30 (rank : 5)	NC score	0.762454 (rank : 10)
Query Neighborhood Hits	409	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_HUMAN
θ value	1.08979e-29 (rank : 6)	NC score	0.743399 (rank : 17)
Query Neighborhood Hits	409	Target Neighborhood Hits	220	Shared Neighborhood Hits	82
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG12_MOUSE
θ value	7.80994e-28 (rank : 7)	NC score	0.780012 (rank : 7)
Query Neighborhood Hits	409	Target Neighborhood Hits	204	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
θ value	5.06226e-27 (rank : 8)	NC score	0.780060 (rank : 6)
Query Neighborhood Hits	409	Target Neighborhood Hits	190	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG09_HUMAN
θ value	1.24688e-25 (rank : 9)	NC score	0.812694 (rank : 3)
Query Neighborhood Hits	409	Target Neighborhood Hits	186	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

ABR_HUMAN
θ value	8.93572e-24 (rank : 10)	NC score	0.727479 (rank : 21)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	92
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

3BP1_HUMAN
θ value	1.42661e-21 (rank : 11)	NC score	0.781580 (rank : 5)
Query Neighborhood Hits	409	Target Neighborhood Hits	376	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
θ value	5.42112e-21 (rank : 12)	NC score	0.782222 (rank : 4)
Query Neighborhood Hits	409	Target Neighborhood Hits	238	Shared Neighborhood Hits	103
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BCR_HUMAN
θ value	5.42112e-21 (rank : 13)	NC score	0.718903 (rank : 24)
Query Neighborhood Hits	409	Target Neighborhood Hits	204	Shared Neighborhood Hits	99
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG04_HUMAN
θ value	9.24701e-21 (rank : 14)	NC score	0.755914 (rank : 11)
Query Neighborhood Hits	409	Target Neighborhood Hits	307	Shared Neighborhood Hits	168
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG26_HUMAN
θ value	1.5773e-20 (rank : 15)	NC score	0.752847 (rank : 14)
Query Neighborhood Hits	409	Target Neighborhood Hits	281	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

GMIP_MOUSE
θ value	2.69047e-20 (rank : 16)	NC score	0.767334 (rank : 8)
Query Neighborhood Hits	409	Target Neighborhood Hits	202	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

OPHN1_MOUSE
θ value	5.07402e-19 (rank : 17)	NC score	0.724562 (rank : 23)
Query Neighborhood Hits	409	Target Neighborhood Hits	174	Shared Neighborhood Hits	66
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

GMIP_HUMAN
θ value	8.65492e-19 (rank : 18)	NC score	0.762887 (rank : 9)
Query Neighborhood Hits	409	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

OPHN1_HUMAN
θ value	1.47631e-18 (rank : 19)	NC score	0.725903 (rank : 22)
Query Neighborhood Hits	409	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

MYO9B_HUMAN
θ value	1.92812e-18 (rank : 20)	NC score	0.406604 (rank : 60)
Query Neighborhood Hits	409	Target Neighborhood Hits	641	Shared Neighborhood Hits	114
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RBP1_MOUSE
θ value	1.92812e-18 (rank : 21)	NC score	0.681662 (rank : 37)
Query Neighborhood Hits	409	Target Neighborhood Hits	493	Shared Neighborhood Hits	73
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

MYO9B_MOUSE
θ value	5.60996e-18 (rank : 22)	NC score	0.407391 (rank : 59)
Query Neighborhood Hits	409	Target Neighborhood Hits	311	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RBP1_HUMAN
θ value	1.63225e-17 (rank : 23)	NC score	0.663482 (rank : 38)
Query Neighborhood Hits	409	Target Neighborhood Hits	521	Shared Neighborhood Hits	77
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CEND3_HUMAN
θ value	2.7842e-17 (rank : 24)	NC score	0.565304 (rank : 52)
Query Neighborhood Hits	409	Target Neighborhood Hits	275	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

RGAP1_HUMAN
θ value	6.20254e-17 (rank : 25)	NC score	0.755000 (rank : 12)
Query Neighborhood Hits	409	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG25_MOUSE
θ value	1.058e-16 (rank : 26)	NC score	0.682238 (rank : 36)
Query Neighborhood Hits	409	Target Neighborhood Hits	492	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

GRLF1_HUMAN
θ value	1.80466e-16 (rank : 27)	NC score	0.731303 (rank : 20)
Query Neighborhood Hits	409	Target Neighborhood Hits	167	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RGAP1_MOUSE
θ value	2.35696e-16 (rank : 28)	NC score	0.754107 (rank : 13)
Query Neighborhood Hits	409	Target Neighborhood Hits	185	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

SRGP1_HUMAN
θ value	4.02038e-16 (rank : 29)	NC score	0.698897 (rank : 33)
Query Neighborhood Hits	409	Target Neighborhood Hits	390	Shared Neighborhood Hits	156
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RHG05_MOUSE
θ value	8.95645e-16 (rank : 30)	NC score	0.700418 (rank : 32)
Query Neighborhood Hits	409	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_HUMAN
θ value	4.44505e-15 (rank : 31)	NC score	0.741170 (rank : 18)
Query Neighborhood Hits	409	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CEND3_MOUSE
θ value	7.58209e-15 (rank : 32)	NC score	0.567930 (rank : 51)
Query Neighborhood Hits	409	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

FNBP2_HUMAN
θ value	1.29331e-14 (rank : 33)	NC score	0.693161 (rank : 34)
Query Neighborhood Hits	409	Target Neighborhood Hits	432	Shared Neighborhood Hits	158
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG25_HUMAN
θ value	1.29331e-14 (rank : 34)	NC score	0.655402 (rank : 39)
Query Neighborhood Hits	409	Target Neighborhood Hits	550	Shared Neighborhood Hits	77
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG01_HUMAN
θ value	1.68911e-14 (rank : 35)	NC score	0.718727 (rank : 25)
Query Neighborhood Hits	409	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG08_HUMAN
θ value	2.88119e-14 (rank : 36)	NC score	0.703342 (rank : 30)
Query Neighborhood Hits	409	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

CEND2_HUMAN
θ value	3.76295e-14 (rank : 37)	NC score	0.591166 (rank : 48)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RHG05_HUMAN
θ value	4.91457e-14 (rank : 38)	NC score	0.689424 (rank : 35)
Query Neighborhood Hits	409	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_MOUSE
θ value	4.91457e-14 (rank : 39)	NC score	0.737563 (rank : 19)
Query Neighborhood Hits	409	Target Neighborhood Hits	105	Shared Neighborhood Hits	64
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SRGP2_HUMAN
θ value	1.86753e-13 (rank : 40)	NC score	0.710737 (rank : 26)
Query Neighborhood Hits	409	Target Neighborhood Hits	331	Shared Neighborhood Hits	160
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG07_MOUSE
θ value	4.16044e-13 (rank : 41)	NC score	0.637785 (rank : 40)
Query Neighborhood Hits	409	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CE005_HUMAN
θ value	5.43371e-13 (rank : 42)	NC score	0.600763 (rank : 44)
Query Neighborhood Hits	409	Target Neighborhood Hits	213	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

SRGP2_MOUSE
θ value	9.26847e-13 (rank : 43)	NC score	0.704246 (rank : 28)
Query Neighborhood Hits	409	Target Neighborhood Hits	324	Shared Neighborhood Hits	163
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CE005_MOUSE
θ value	1.58096e-12 (rank : 44)	NC score	0.596279 (rank : 46)
Query Neighborhood Hits	409	Target Neighborhood Hits	238	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG07_HUMAN
θ value	3.52202e-12 (rank : 45)	NC score	0.631254 (rank : 41)
Query Neighborhood Hits	409	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG08_MOUSE
θ value	4.59992e-12 (rank : 46)	NC score	0.703292 (rank : 31)
Query Neighborhood Hits	409	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG18_HUMAN
θ value	1.133e-10 (rank : 47)	NC score	0.710218 (rank : 27)
Query Neighborhood Hits	409	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

STA13_HUMAN
θ value	1.133e-10 (rank : 48)	NC score	0.591115 (rank : 49)
Query Neighborhood Hits	409	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STAR8_MOUSE
θ value	1.9326e-10 (rank : 49)	NC score	0.598285 (rank : 45)
Query Neighborhood Hits	409	Target Neighborhood Hits	101	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG18_MOUSE
θ value	2.52405e-10 (rank : 50)	NC score	0.703954 (rank : 29)
Query Neighborhood Hits	409	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

STAR8_HUMAN
θ value	4.30538e-10 (rank : 51)	NC score	0.594655 (rank : 47)
Query Neighborhood Hits	409	Target Neighborhood Hits	216	Shared Neighborhood Hits	78
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
θ value	5.62301e-10 (rank : 52)	NC score	0.581081 (rank : 50)
Query Neighborhood Hits	409	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND1_MOUSE
θ value	1.63604e-09 (rank : 53)	NC score	0.501698 (rank : 55)
Query Neighborhood Hits	409	Target Neighborhood Hits	260	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
θ value	2.79066e-09 (rank : 54)	NC score	0.482253 (rank : 56)
Query Neighborhood Hits	409	Target Neighborhood Hits	284	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

K1688_MOUSE
θ value	6.21693e-09 (rank : 55)	NC score	0.543275 (rank : 53)
Query Neighborhood Hits	409	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

P85A_HUMAN
θ value	8.11959e-09 (rank : 56)	NC score	0.420728 (rank : 57)
Query Neighborhood Hits	409	Target Neighborhood Hits	479	Shared Neighborhood Hits	115
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

K1688_HUMAN
θ value	1.06045e-08 (rank : 57)	NC score	0.530734 (rank : 54)
Query Neighborhood Hits	409	Target Neighborhood Hits	217	Shared Neighborhood Hits	82
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

P85A_MOUSE
θ value	1.38499e-08 (rank : 58)	NC score	0.415902 (rank : 58)
Query Neighborhood Hits	409	Target Neighborhood Hits	435	Shared Neighborhood Hits	119
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

TAGAP_HUMAN
θ value	1.17247e-07 (rank : 59)	NC score	0.628284 (rank : 42)
Query Neighborhood Hits	409	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

GRAP_HUMAN
θ value	5.81887e-07 (rank : 60)	NC score	0.246921 (rank : 71)
Query Neighborhood Hits	409	Target Neighborhood Hits	307	Shared Neighborhood Hits	136
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

ITSN1_MOUSE
θ value	5.81887e-07 (rank : 61)	NC score	0.195264 (rank : 114)
Query Neighborhood Hits	409	Target Neighborhood Hits	1669	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

GRAP_MOUSE
θ value	2.21117e-06 (rank : 62)	NC score	0.243978 (rank : 72)
Query Neighborhood Hits	409	Target Neighborhood Hits	309	Shared Neighborhood Hits	135
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

ITSN1_HUMAN
θ value	2.21117e-06 (rank : 63)	NC score	0.194439 (rank : 115)
Query Neighborhood Hits	409	Target Neighborhood Hits	1757	Shared Neighborhood Hits	186
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

TAGAP_MOUSE
θ value	4.92598e-06 (rank : 64)	NC score	0.627499 (rank : 43)
Query Neighborhood Hits	409	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

MUC1_HUMAN
θ value	1.09739e-05 (rank : 65)	NC score	0.083738 (rank : 237)
Query Neighborhood Hits	409	Target Neighborhood Hits	975	Shared Neighborhood Hits	112
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ARHG4_HUMAN
θ value	4.1701e-05 (rank : 66)	NC score	0.209376 (rank : 98)
Query Neighborhood Hits	409	Target Neighborhood Hits	242	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

MAGE1_HUMAN
θ value	5.44631e-05 (rank : 67)	NC score	0.065171 (rank : 307)
Query Neighborhood Hits	409	Target Neighborhood Hits	1389	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

I5P2_HUMAN
θ value	9.29e-05 (rank : 68)	NC score	0.339603 (rank : 61)
Query Neighborhood Hits	409	Target Neighborhood Hits	86	Shared Neighborhood Hits	55
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
θ value	9.29e-05 (rank : 69)	NC score	0.331420 (rank : 62)
Query Neighborhood Hits	409	Target Neighborhood Hits	77	Shared Neighborhood Hits	55
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

M3K9_HUMAN
θ value	0.00020696 (rank : 70)	NC score	0.054251 (rank : 387)
Query Neighborhood Hits	409	Target Neighborhood Hits	1123	Shared Neighborhood Hits	133
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NFH_MOUSE
θ value	0.000786445 (rank : 71)	NC score	0.053909 (rank : 391)
Query Neighborhood Hits	409	Target Neighborhood Hits	2247	Shared Neighborhood Hits	164
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MK15_HUMAN
θ value	0.00102713 (rank : 72)	NC score	0.008125 (rank : 590)
Query Neighborhood Hits	409	Target Neighborhood Hits	1038	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

SRC8_MOUSE
θ value	0.00102713 (rank : 73)	NC score	0.241988 (rank : 74)
Query Neighborhood Hits	409	Target Neighborhood Hits	292	Shared Neighborhood Hits	118
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

STAC3_HUMAN
θ value	0.00102713 (rank : 74)	NC score	0.252046 (rank : 70)
Query Neighborhood Hits	409	Target Neighborhood Hits	228	Shared Neighborhood Hits	109
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	0.00102713 (rank : 75)	NC score	0.254533 (rank : 69)
Query Neighborhood Hits	409	Target Neighborhood Hits	232	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CD2AP_MOUSE
θ value	0.00134147 (rank : 76)	NC score	0.264411 (rank : 65)
Query Neighborhood Hits	409	Target Neighborhood Hits	336	Shared Neighborhood Hits	140
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

ITSN2_HUMAN
θ value	0.00134147 (rank : 77)	NC score	0.193277 (rank : 116)
Query Neighborhood Hits	409	Target Neighborhood Hits	1173	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

BCAR1_MOUSE
θ value	0.00175202 (rank : 78)	NC score	0.200804 (rank : 107)
Query Neighborhood Hits	409	Target Neighborhood Hits	438	Shared Neighborhood Hits	151
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

HCLS1_HUMAN
θ value	0.00175202 (rank : 79)	NC score	0.262393 (rank : 67)
Query Neighborhood Hits	409	Target Neighborhood Hits	358	Shared Neighborhood Hits	136
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

ITSN2_MOUSE
θ value	0.00175202 (rank : 80)	NC score	0.184253 (rank : 122)
Query Neighborhood Hits	409	Target Neighborhood Hits	1371	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

OSTF1_MOUSE
θ value	0.00175202 (rank : 81)	NC score	0.178976 (rank : 127)
Query Neighborhood Hits	409	Target Neighborhood Hits	467	Shared Neighborhood Hits	125
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

CD2AP_HUMAN
θ value	0.00228821 (rank : 82)	NC score	0.267432 (rank : 63)
Query Neighborhood Hits	409	Target Neighborhood Hits	315	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

K1543_MOUSE
θ value	0.00228821 (rank : 83)	NC score	0.088065 (rank : 230)
Query Neighborhood Hits	409	Target Neighborhood Hits	497	Shared Neighborhood Hits	77
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

OSTF1_HUMAN
θ value	0.00228821 (rank : 84)	NC score	0.181448 (rank : 124)
Query Neighborhood Hits	409	Target Neighborhood Hits	466	Shared Neighborhood Hits	126
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ASPP1_HUMAN
θ value	0.00298849 (rank : 85)	NC score	0.149847 (rank : 151)
Query Neighborhood Hits	409	Target Neighborhood Hits	956	Shared Neighborhood Hits	150
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

HCLS1_MOUSE
θ value	0.00298849 (rank : 86)	NC score	0.258436 (rank : 68)
Query Neighborhood Hits	409	Target Neighborhood Hits	329	Shared Neighborhood Hits	132
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

MYO1E_HUMAN
θ value	0.00298849 (rank : 87)	NC score	0.128924 (rank : 165)
Query Neighborhood Hits	409	Target Neighborhood Hits	293	Shared Neighborhood Hits	125
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

STAM2_HUMAN
θ value	0.00298849 (rank : 88)	NC score	0.212041 (rank : 97)
Query Neighborhood Hits	409	Target Neighborhood Hits	288	Shared Neighborhood Hits	125
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

ARHG9_HUMAN
θ value	0.00390308 (rank : 89)	NC score	0.206764 (rank : 102)
Query Neighborhood Hits	409	Target Neighborhood Hits	235	Shared Neighborhood Hits	123
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	0.00390308 (rank : 90)	NC score	0.206944 (rank : 101)
Query Neighborhood Hits	409	Target Neighborhood Hits	234	Shared Neighborhood Hits	121
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

SON_HUMAN
θ value	0.00390308 (rank : 91)	NC score	0.072873 (rank : 272)
Query Neighborhood Hits	409	Target Neighborhood Hits	1568	Shared Neighborhood Hits	169
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

STAM2_MOUSE
θ value	0.00390308 (rank : 92)	NC score	0.213557 (rank : 96)
Query Neighborhood Hits	409	Target Neighborhood Hits	285	Shared Neighborhood Hits	125
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

ASPP1_MOUSE
θ value	0.00509761 (rank : 93)	NC score	0.145622 (rank : 152)
Query Neighborhood Hits	409	Target Neighborhood Hits	1244	Shared Neighborhood Hits	178
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MYO1F_HUMAN
θ value	0.00509761 (rank : 94)	NC score	0.132028 (rank : 162)
Query Neighborhood Hits	409	Target Neighborhood Hits	275	Shared Neighborhood Hits	127
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

SRC8_HUMAN
θ value	0.00509761 (rank : 95)	NC score	0.237176 (rank : 77)
Query Neighborhood Hits	409	Target Neighborhood Hits	269	Shared Neighborhood Hits	116
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

ARHG6_MOUSE
θ value	0.00665767 (rank : 96)	NC score	0.207913 (rank : 100)
Query Neighborhood Hits	409	Target Neighborhood Hits	394	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

M3K11_HUMAN
θ value	0.00665767 (rank : 97)	NC score	0.056424 (rank : 376)
Query Neighborhood Hits	409	Target Neighborhood Hits	1136	Shared Neighborhood Hits	161
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

BCAR1_HUMAN
θ value	0.00869519 (rank : 98)	NC score	0.188088 (rank : 119)
Query Neighborhood Hits	409	Target Neighborhood Hits	554	Shared Neighborhood Hits	162
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

IASPP_HUMAN
θ value	0.00869519 (rank : 99)	NC score	0.167862 (rank : 137)
Query Neighborhood Hits	409	Target Neighborhood Hits	688	Shared Neighborhood Hits	165
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PPIP1_HUMAN
θ value	0.00869519 (rank : 100)	NC score	0.206236 (rank : 103)
Query Neighborhood Hits	409	Target Neighborhood Hits	389	Shared Neighborhood Hits	122
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SHAN1_HUMAN
θ value	0.00869519 (rank : 101)	NC score	0.101944 (rank : 199)
Query Neighborhood Hits	409	Target Neighborhood Hits	1041	Shared Neighborhood Hits	189
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

STAM1_MOUSE
θ value	0.00869519 (rank : 102)	NC score	0.216727 (rank : 94)
Query Neighborhood Hits	409	Target Neighborhood Hits	273	Shared Neighborhood Hits	127
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

CSF1_HUMAN
θ value	0.0113563 (rank : 103)	NC score	0.062503 (rank : 327)
Query Neighborhood Hits	409	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

MYO1F_MOUSE
θ value	0.0113563 (rank : 104)	NC score	0.130583 (rank : 163)
Query Neighborhood Hits	409	Target Neighborhood Hits	262	Shared Neighborhood Hits	120
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NCK2_HUMAN
θ value	0.0113563 (rank : 105)	NC score	0.235367 (rank : 79)
Query Neighborhood Hits	409	Target Neighborhood Hits	310	Shared Neighborhood Hits	129
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

PI5PA_HUMAN
θ value	0.0113563 (rank : 106)	NC score	0.093632 (rank : 212)
Query Neighborhood Hits	409	Target Neighborhood Hits	749	Shared Neighborhood Hits	123
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

STAM1_HUMAN
θ value	0.0113563 (rank : 107)	NC score	0.217316 (rank : 92)
Query Neighborhood Hits	409	Target Neighborhood Hits	271	Shared Neighborhood Hits	125
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

NCK1_HUMAN
θ value	0.0148317 (rank : 108)	NC score	0.220855 (rank : 90)
Query Neighborhood Hits	409	Target Neighborhood Hits	312	Shared Neighborhood Hits	128
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

PTPRN_MOUSE
θ value	0.0148317 (rank : 109)	NC score	0.017688 (rank : 555)
Query Neighborhood Hits	409	Target Neighborhood Hits	240	Shared Neighborhood Hits	33
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

TACC3_HUMAN
θ value	0.0148317 (rank : 110)	NC score	0.055725 (rank : 380)
Query Neighborhood Hits	409	Target Neighborhood Hits	779	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

DNMBP_HUMAN
θ value	0.0193708 (rank : 111)	NC score	0.223160 (rank : 86)
Query Neighborhood Hits	409	Target Neighborhood Hits	413	Shared Neighborhood Hits	141
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

REXO1_MOUSE
θ value	0.0193708 (rank : 112)	NC score	0.052077 (rank : 409)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

SH3K1_HUMAN
θ value	0.0193708 (rank : 113)	NC score	0.263559 (rank : 66)
Query Neighborhood Hits	409	Target Neighborhood Hits	341	Shared Neighborhood Hits	133
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	0.0193708 (rank : 114)	NC score	0.266947 (rank : 64)
Query Neighborhood Hits	409	Target Neighborhood Hits	332	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

IASPP_MOUSE
θ value	0.0252991 (rank : 115)	NC score	0.160905 (rank : 143)
Query Neighborhood Hits	409	Target Neighborhood Hits	1024	Shared Neighborhood Hits	200
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NGEF_HUMAN
θ value	0.0252991 (rank : 116)	NC score	0.127952 (rank : 166)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

RC3H1_HUMAN
θ value	0.0252991 (rank : 117)	NC score	0.032668 (rank : 499)
Query Neighborhood Hits	409	Target Neighborhood Hits	433	Shared Neighborhood Hits	39
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

VAV2_MOUSE
θ value	0.0252991 (rank : 118)	NC score	0.206003 (rank : 104)
Query Neighborhood Hits	409	Target Neighborhood Hits	456	Shared Neighborhood Hits	141
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

DCC_MOUSE
θ value	0.0330416 (rank : 119)	NC score	0.018003 (rank : 552)
Query Neighborhood Hits	409	Target Neighborhood Hits	896	Shared Neighborhood Hits	59
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

FMNL_HUMAN
θ value	0.0330416 (rank : 120)	NC score	0.079624 (rank : 252)
Query Neighborhood Hits	409	Target Neighborhood Hits	529	Shared Neighborhood Hits	81
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GRAP2_HUMAN
θ value	0.0330416 (rank : 121)	NC score	0.226185 (rank : 83)
Query Neighborhood Hits	409	Target Neighborhood Hits	304	Shared Neighborhood Hits	132
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

VAV2_HUMAN
θ value	0.0330416 (rank : 122)	NC score	0.204252 (rank : 106)
Query Neighborhood Hits	409	Target Neighborhood Hits	453	Shared Neighborhood Hits	134
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

ALEX_HUMAN
θ value	0.0431538 (rank : 123)	NC score	0.090123 (rank : 223)
Query Neighborhood Hits	409	Target Neighborhood Hits	361	Shared Neighborhood Hits	64
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARHG4_MOUSE
θ value	0.0431538 (rank : 124)	NC score	0.175005 (rank : 133)
Query Neighborhood Hits	409	Target Neighborhood Hits	185	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHGG_HUMAN
θ value	0.0431538 (rank : 125)	NC score	0.108792 (rank : 187)
Query Neighborhood Hits	409	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

GRAP2_MOUSE
θ value	0.0431538 (rank : 126)	NC score	0.225047 (rank : 85)
Query Neighborhood Hits	409	Target Neighborhood Hits	297	Shared Neighborhood Hits	131
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

NGEF_MOUSE
θ value	0.0431538 (rank : 127)	NC score	0.127554 (rank : 168)
Query Neighborhood Hits	409	Target Neighborhood Hits	228	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

STAC_MOUSE
θ value	0.0431538 (rank : 128)	NC score	0.242710 (rank : 73)
Query Neighborhood Hits	409	Target Neighborhood Hits	268	Shared Neighborhood Hits	121
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

AHI1_HUMAN
θ value	0.0563607 (rank : 129)	NC score	0.154052 (rank : 149)
Query Neighborhood Hits	409	Target Neighborhood Hits	537	Shared Neighborhood Hits	129
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ARHG7_MOUSE
θ value	0.0563607 (rank : 130)	NC score	0.221622 (rank : 89)
Query Neighborhood Hits	409	Target Neighborhood Hits	396	Shared Neighborhood Hits	130
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

PPIP1_MOUSE
θ value	0.0563607 (rank : 131)	NC score	0.197230 (rank : 112)
Query Neighborhood Hits	409	Target Neighborhood Hits	377	Shared Neighborhood Hits	122
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

SNX22_HUMAN
θ value	0.0563607 (rank : 132)	NC score	0.068212 (rank : 292)
Query Neighborhood Hits	409	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q96L94, Q9H844	Gene names	SNX22
Domain Architecture
Description	Sorting nexin-22.

STAC_HUMAN
θ value	0.0563607 (rank : 133)	NC score	0.240160 (rank : 75)
Query Neighborhood Hits	409	Target Neighborhood Hits	276	Shared Neighborhood Hits	120
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VAV_MOUSE
θ value	0.0563607 (rank : 134)	NC score	0.204857 (rank : 105)
Query Neighborhood Hits	409	Target Neighborhood Hits	430	Shared Neighborhood Hits	136
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VINEX_MOUSE
θ value	0.0563607 (rank : 135)	NC score	0.237863 (rank : 76)
Query Neighborhood Hits	409	Target Neighborhood Hits	286	Shared Neighborhood Hits	133
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

DNMBP_MOUSE
θ value	0.0736092 (rank : 136)	NC score	0.217378 (rank : 91)
Query Neighborhood Hits	409	Target Neighborhood Hits	435	Shared Neighborhood Hits	149
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

KCNQ5_HUMAN
θ value	0.0736092 (rank : 137)	NC score	0.015572 (rank : 566)
Query Neighborhood Hits	409	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

VAV_HUMAN
θ value	0.0736092 (rank : 138)	NC score	0.200714 (rank : 108)
Query Neighborhood Hits	409	Target Neighborhood Hits	452	Shared Neighborhood Hits	134
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ALO17_HUMAN
θ value	0.0961366 (rank : 139)	NC score	0.065806 (rank : 302)
Query Neighborhood Hits	409	Target Neighborhood Hits	317	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ARHG7_HUMAN
θ value	0.0961366 (rank : 140)	NC score	0.213841 (rank : 95)
Query Neighborhood Hits	409	Target Neighborhood Hits	347	Shared Neighborhood Hits	128
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

CEP68_MOUSE
θ value	0.0961366 (rank : 141)	NC score	0.040615 (rank : 464)
Query Neighborhood Hits	409	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

M3KL4_HUMAN
θ value	0.0961366 (rank : 142)	NC score	0.050724 (rank : 428)
Query Neighborhood Hits	409	Target Neighborhood Hits	1087	Shared Neighborhood Hits	125
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

PAF49_HUMAN
θ value	0.0961366 (rank : 143)	NC score	0.071756 (rank : 277)
Query Neighborhood Hits	409	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

ULK1_MOUSE
θ value	0.0961366 (rank : 144)	NC score	0.006354 (rank : 599)
Query Neighborhood Hits	409	Target Neighborhood Hits	1214	Shared Neighborhood Hits	78
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ARHG6_HUMAN
θ value	0.125558 (rank : 145)	NC score	0.200115 (rank : 109)
Query Neighborhood Hits	409	Target Neighborhood Hits	376	Shared Neighborhood Hits	124
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

CT032_HUMAN
θ value	0.125558 (rank : 146)	NC score	0.184512 (rank : 121)
Query Neighborhood Hits	409	Target Neighborhood Hits	235	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

NACAM_MOUSE
θ value	0.125558 (rank : 147)	NC score	0.079736 (rank : 251)
Query Neighborhood Hits	409	Target Neighborhood Hits	1866	Shared Neighborhood Hits	185
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RANB3_MOUSE
θ value	0.125558 (rank : 148)	NC score	0.041175 (rank : 461)
Query Neighborhood Hits	409	Target Neighborhood Hits	123	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

SHAN2_MOUSE
θ value	0.125558 (rank : 149)	NC score	0.113417 (rank : 181)
Query Neighborhood Hits	409	Target Neighborhood Hits	446	Shared Neighborhood Hits	112
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

VINEX_HUMAN
θ value	0.125558 (rank : 150)	NC score	0.232886 (rank : 80)
Query Neighborhood Hits	409	Target Neighborhood Hits	270	Shared Neighborhood Hits	136
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

ZIM10_HUMAN
θ value	0.125558 (rank : 151)	NC score	0.051691 (rank : 416)
Query Neighborhood Hits	409	Target Neighborhood Hits	577	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN687_HUMAN
θ value	0.125558 (rank : 152)	NC score	0.015124 (rank : 568)
Query Neighborhood Hits	409	Target Neighborhood Hits	1244	Shared Neighborhood Hits	108
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

BCL9_HUMAN
θ value	0.163984 (rank : 153)	NC score	0.069607 (rank : 285)
Query Neighborhood Hits	409	Target Neighborhood Hits	1008	Shared Neighborhood Hits	138
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CAC1G_HUMAN
θ value	0.163984 (rank : 154)	NC score	0.027700 (rank : 511)
Query Neighborhood Hits	409	Target Neighborhood Hits	587	Shared Neighborhood Hits	70
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

GRB2_HUMAN
θ value	0.163984 (rank : 155)	NC score	0.229294 (rank : 81)
Query Neighborhood Hits	409	Target Neighborhood Hits	310	Shared Neighborhood Hits	131
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	0.163984 (rank : 156)	NC score	0.229153 (rank : 82)
Query Neighborhood Hits	409	Target Neighborhood Hits	312	Shared Neighborhood Hits	131
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

SP7_MOUSE
θ value	0.163984 (rank : 157)	NC score	0.001577 (rank : 607)
Query Neighborhood Hits	409	Target Neighborhood Hits	756	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

DMRTD_MOUSE
θ value	0.21417 (rank : 158)	NC score	0.044928 (rank : 447)
Query Neighborhood Hits	409	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

DOK7_MOUSE
θ value	0.21417 (rank : 159)	NC score	0.042037 (rank : 455)
Query Neighborhood Hits	409	Target Neighborhood Hits	169	Shared Neighborhood Hits	30
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

RUSC2_MOUSE
θ value	0.21417 (rank : 160)	NC score	0.080135 (rank : 250)
Query Neighborhood Hits	409	Target Neighborhood Hits	305	Shared Neighborhood Hits	82
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

AOC3_HUMAN
θ value	0.279714 (rank : 161)	NC score	0.027908 (rank : 510)
Query Neighborhood Hits	409	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q16853, Q45F94	Gene names	AOC3, VAP1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1) (HPAO).

CSPG5_MOUSE
θ value	0.279714 (rank : 162)	NC score	0.049496 (rank : 438)
Query Neighborhood Hits	409	Target Neighborhood Hits	211	Shared Neighborhood Hits	24
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

P85B_HUMAN
θ value	0.279714 (rank : 163)	NC score	0.159808 (rank : 144)
Query Neighborhood Hits	409	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RBP2_HUMAN
θ value	0.279714 (rank : 164)	NC score	0.014738 (rank : 570)
Query Neighborhood Hits	409	Target Neighborhood Hits	249	Shared Neighborhood Hits	19
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

AHI1_MOUSE
θ value	0.365318 (rank : 165)	NC score	0.151346 (rank : 150)
Query Neighborhood Hits	409	Target Neighborhood Hits	496	Shared Neighborhood Hits	131
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

CO4A3_HUMAN
θ value	0.365318 (rank : 166)	NC score	0.039136 (rank : 468)
Query Neighborhood Hits	409	Target Neighborhood Hits	421	Shared Neighborhood Hits	76
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

HAIR_HUMAN
θ value	0.365318 (rank : 167)	NC score	0.039473 (rank : 467)
Query Neighborhood Hits	409	Target Neighborhood Hits	172	Shared Neighborhood Hits	32
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

NCOR1_MOUSE
θ value	0.365318 (rank : 168)	NC score	0.037401 (rank : 477)
Query Neighborhood Hits	409	Target Neighborhood Hits	521	Shared Neighborhood Hits	52
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

OGFR_HUMAN
θ value	0.365318 (rank : 169)	NC score	0.077669 (rank : 257)
Query Neighborhood Hits	409	Target Neighborhood Hits	1582	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRP2_MOUSE
θ value	0.365318 (rank : 170)	NC score	0.135829 (rank : 159)
Query Neighborhood Hits	409	Target Neighborhood Hits	347	Shared Neighborhood Hits	82
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RGS3_HUMAN
θ value	0.365318 (rank : 171)	NC score	0.058804 (rank : 358)
Query Neighborhood Hits	409	Target Neighborhood Hits	1375	Shared Neighborhood Hits	145
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	0.365318 (rank : 172)	NC score	0.075207 (rank : 264)
Query Neighborhood Hits	409	Target Neighborhood Hits	1621	Shared Neighborhood Hits	179
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SYNPO_MOUSE
θ value	0.365318 (rank : 173)	NC score	0.047135 (rank : 442)
Query Neighborhood Hits	409	Target Neighborhood Hits	242	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TULP4_HUMAN
θ value	0.365318 (rank : 174)	NC score	0.030801 (rank : 502)
Query Neighborhood Hits	409	Target Neighborhood Hits	426	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

VAV3_HUMAN
θ value	0.365318 (rank : 175)	NC score	0.198615 (rank : 110)
Query Neighborhood Hits	409	Target Neighborhood Hits	398	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

ABI2_HUMAN
θ value	0.47712 (rank : 176)	NC score	0.225308 (rank : 84)
Query Neighborhood Hits	409	Target Neighborhood Hits	350	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	0.47712 (rank : 177)	NC score	0.216974 (rank : 93)
Query Neighborhood Hits	409	Target Neighborhood Hits	266	Shared Neighborhood Hits	132
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

CEP35_HUMAN
θ value	0.47712 (rank : 178)	NC score	0.021982 (rank : 537)
Query Neighborhood Hits	409	Target Neighborhood Hits	811	Shared Neighborhood Hits	31
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CRKL_HUMAN
θ value	0.47712 (rank : 179)	NC score	0.186521 (rank : 120)
Query Neighborhood Hits	409	Target Neighborhood Hits	313	Shared Neighborhood Hits	129
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

FUBP1_HUMAN
θ value	0.47712 (rank : 180)	NC score	0.034837 (rank : 489)
Query Neighborhood Hits	409	Target Neighborhood Hits	136	Shared Neighborhood Hits	33
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	0.47712 (rank : 181)	NC score	0.035189 (rank : 486)
Query Neighborhood Hits	409	Target Neighborhood Hits	144	Shared Neighborhood Hits	36
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

SH3G2_MOUSE
θ value	0.47712 (rank : 182)	NC score	0.189029 (rank : 118)
Query Neighborhood Hits	409	Target Neighborhood Hits	319	Shared Neighborhood Hits	124
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

ZN414_MOUSE
θ value	0.47712 (rank : 183)	NC score	0.022023 (rank : 536)
Query Neighborhood Hits	409	Target Neighborhood Hits	473	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

K1802_MOUSE
θ value	0.62314 (rank : 184)	NC score	0.045528 (rank : 444)
Query Neighborhood Hits	409	Target Neighborhood Hits	1596	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LPP_HUMAN
θ value	0.62314 (rank : 185)	NC score	0.031585 (rank : 501)
Query Neighborhood Hits	409	Target Neighborhood Hits	775	Shared Neighborhood Hits	84
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAGA5_HUMAN
θ value	0.62314 (rank : 186)	NC score	0.016605 (rank : 561)
Query Neighborhood Hits	409	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P43359	Gene names	MAGEA5, MAGE5
Domain Architecture
Description	Melanoma-associated antigen 5 (MAGE-5 antigen).

P85B_MOUSE
θ value	0.62314 (rank : 187)	NC score	0.126267 (rank : 171)
Query Neighborhood Hits	409	Target Neighborhood Hits	519	Shared Neighborhood Hits	62
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SOX13_HUMAN
θ value	0.62314 (rank : 188)	NC score	0.030611 (rank : 503)
Query Neighborhood Hits	409	Target Neighborhood Hits	464	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

STON1_MOUSE
θ value	0.62314 (rank : 189)	NC score	0.040716 (rank : 463)
Query Neighborhood Hits	409	Target Neighborhood Hits	50	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

VAV3_MOUSE
θ value	0.62314 (rank : 190)	NC score	0.197009 (rank : 113)
Query Neighborhood Hits	409	Target Neighborhood Hits	404	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

BAT2_MOUSE
θ value	0.813845 (rank : 191)	NC score	0.091545 (rank : 219)
Query Neighborhood Hits	409	Target Neighborhood Hits	947	Shared Neighborhood Hits	139
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CI079_HUMAN
θ value	0.813845 (rank : 192)	NC score	0.045371 (rank : 445)
Query Neighborhood Hits	409	Target Neighborhood Hits	288	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CRKL_MOUSE
θ value	0.813845 (rank : 193)	NC score	0.177532 (rank : 130)
Query Neighborhood Hits	409	Target Neighborhood Hits	307	Shared Neighborhood Hits	124
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

DAB2_HUMAN
θ value	0.813845 (rank : 194)	NC score	0.023417 (rank : 530)
Query Neighborhood Hits	409	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

GLI1_MOUSE
θ value	0.813845 (rank : 195)	NC score	-0.003250 (rank : 616)
Query Neighborhood Hits	409	Target Neighborhood Hits	785	Shared Neighborhood Hits	28
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

GNAS1_MOUSE
θ value	0.813845 (rank : 196)	NC score	0.038956 (rank : 469)
Query Neighborhood Hits	409	Target Neighborhood Hits	651	Shared Neighborhood Hits	101
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IL3B2_MOUSE
θ value	0.813845 (rank : 197)	NC score	0.050397 (rank : 433)
Query Neighborhood Hits	409	Target Neighborhood Hits	372	Shared Neighborhood Hits	65
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

JADE2_MOUSE
θ value	0.813845 (rank : 198)	NC score	0.033971 (rank : 492)
Query Neighborhood Hits	409	Target Neighborhood Hits	560	Shared Neighborhood Hits	68
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

NCF2_HUMAN
θ value	0.813845 (rank : 199)	NC score	0.236214 (rank : 78)
Query Neighborhood Hits	409	Target Neighborhood Hits	229	Shared Neighborhood Hits	121
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NUAK1_MOUSE
θ value	0.813845 (rank : 200)	NC score	-0.000356 (rank : 612)
Query Neighborhood Hits	409	Target Neighborhood Hits	881	Shared Neighborhood Hits	20
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

PACN2_HUMAN
θ value	0.813845 (rank : 201)	NC score	0.170228 (rank : 135)
Query Neighborhood Hits	409	Target Neighborhood Hits	339	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
θ value	0.813845 (rank : 202)	NC score	0.166509 (rank : 139)
Query Neighborhood Hits	409	Target Neighborhood Hits	382	Shared Neighborhood Hits	123
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SLIK3_HUMAN
θ value	0.813845 (rank : 203)	NC score	0.007135 (rank : 595)
Query Neighborhood Hits	409	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	O94933	Gene names	SLITRK3, KIAA0848
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 3 precursor.

SLIK3_MOUSE
θ value	0.813845 (rank : 204)	NC score	0.007105 (rank : 596)
Query Neighborhood Hits	409	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

UBQL3_HUMAN
θ value	0.813845 (rank : 205)	NC score	0.027953 (rank : 509)
Query Neighborhood Hits	409	Target Neighborhood Hits	141	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

CO039_HUMAN
θ value	1.06291 (rank : 206)	NC score	0.053667 (rank : 395)
Query Neighborhood Hits	409	Target Neighborhood Hits	264	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

COBA1_MOUSE
θ value	1.06291 (rank : 207)	NC score	0.036832 (rank : 478)
Query Neighborhood Hits	409	Target Neighborhood Hits	487	Shared Neighborhood Hits	77
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

IL3RB_MOUSE
θ value	1.06291 (rank : 208)	NC score	0.050459 (rank : 432)
Query Neighborhood Hits	409	Target Neighborhood Hits	355	Shared Neighborhood Hits	61
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

NCF1_MOUSE
θ value	1.06291 (rank : 209)	NC score	0.178988 (rank : 126)
Query Neighborhood Hits	409	Target Neighborhood Hits	198	Shared Neighborhood Hits	108
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

NOXO1_HUMAN
θ value	1.06291 (rank : 210)	NC score	0.126504 (rank : 170)
Query Neighborhood Hits	409	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

PACN3_MOUSE
θ value	1.06291 (rank : 211)	NC score	0.156872 (rank : 147)
Query Neighborhood Hits	409	Target Neighborhood Hits	380	Shared Neighborhood Hits	117
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

SH3G1_HUMAN
θ value	1.06291 (rank : 212)	NC score	0.178778 (rank : 128)
Query Neighborhood Hits	409	Target Neighborhood Hits	307	Shared Neighborhood Hits	118
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

ZN385_HUMAN
θ value	1.06291 (rank : 213)	NC score	0.048508 (rank : 441)
Query Neighborhood Hits	409	Target Neighborhood Hits	614	Shared Neighborhood Hits	88
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZNFX1_HUMAN
θ value	1.06291 (rank : 214)	NC score	0.015493 (rank : 567)
Query Neighborhood Hits	409	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ABI1_MOUSE
θ value	1.38821 (rank : 215)	NC score	0.208059 (rank : 99)
Query Neighborhood Hits	409	Target Neighborhood Hits	246	Shared Neighborhood Hits	135
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ADA15_MOUSE
θ value	1.38821 (rank : 216)	NC score	0.006498 (rank : 597)
Query Neighborhood Hits	409	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

APXL_HUMAN
θ value	1.38821 (rank : 217)	NC score	0.041580 (rank : 458)
Query Neighborhood Hits	409	Target Neighborhood Hits	553	Shared Neighborhood Hits	64
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CJ108_HUMAN
θ value	1.38821 (rank : 218)	NC score	0.041380 (rank : 459)
Query Neighborhood Hits	409	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CND2_HUMAN
θ value	1.38821 (rank : 219)	NC score	0.029484 (rank : 505)
Query Neighborhood Hits	409	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q15003, Q8TB87	Gene names	NCAPH, BRRN, BRRN1, CAPH, KIAA0074
Domain Architecture
Description	Condensin complex subunit 2 (Non-SMC condensin I complex subunit H) (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (XCAP-H homolog).

CPSF6_HUMAN
θ value	1.38821 (rank : 220)	NC score	0.107057 (rank : 189)
Query Neighborhood Hits	409	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	1.38821 (rank : 221)	NC score	0.106836 (rank : 190)
Query Neighborhood Hits	409	Target Neighborhood Hits	356	Shared Neighborhood Hits	73
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

EDA_HUMAN
θ value	1.38821 (rank : 222)	NC score	0.042104 (rank : 454)
Query Neighborhood Hits	409	Target Neighborhood Hits	134	Shared Neighborhood Hits	43
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EDA_MOUSE
θ value	1.38821 (rank : 223)	NC score	0.040981 (rank : 462)
Query Neighborhood Hits	409	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

EPN2_HUMAN
θ value	1.38821 (rank : 224)	NC score	0.021857 (rank : 539)
Query Neighborhood Hits	409	Target Neighborhood Hits	156	Shared Neighborhood Hits	15
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

LR37A_HUMAN
θ value	1.38821 (rank : 225)	NC score	0.028364 (rank : 507)
Query Neighborhood Hits	409	Target Neighborhood Hits	720	Shared Neighborhood Hits	68
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MIA2_MOUSE
θ value	1.38821 (rank : 226)	NC score	0.045244 (rank : 446)
Query Neighborhood Hits	409	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

MLL3_MOUSE
θ value	1.38821 (rank : 227)	NC score	0.036605 (rank : 480)
Query Neighborhood Hits	409	Target Neighborhood Hits	1399	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NCOR1_HUMAN
θ value	1.38821 (rank : 228)	NC score	0.038453 (rank : 474)
Query Neighborhood Hits	409	Target Neighborhood Hits	577	Shared Neighborhood Hits	52
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NUP53_MOUSE
θ value	1.38821 (rank : 229)	NC score	0.038901 (rank : 471)
Query Neighborhood Hits	409	Target Neighborhood Hits	94	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

PELP1_MOUSE
θ value	1.38821 (rank : 230)	NC score	0.074070 (rank : 266)
Query Neighborhood Hits	409	Target Neighborhood Hits	709	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PTC2_HUMAN
θ value	1.38821 (rank : 231)	NC score	0.017645 (rank : 557)
Query Neighborhood Hits	409	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

RUSC1_HUMAN
θ value	1.38821 (rank : 232)	NC score	0.127583 (rank : 167)
Query Neighborhood Hits	409	Target Neighborhood Hits	226	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SMOO_HUMAN
θ value	1.38821 (rank : 233)	NC score	0.043953 (rank : 450)
Query Neighborhood Hits	409	Target Neighborhood Hits	391	Shared Neighborhood Hits	67
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SMR3B_HUMAN
θ value	1.38821 (rank : 234)	NC score	0.073580 (rank : 268)
Query Neighborhood Hits	409	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SP7_HUMAN
θ value	1.38821 (rank : 235)	NC score	-0.000552 (rank : 615)
Query Neighborhood Hits	409	Target Neighborhood Hits	734	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

SRBS1_HUMAN
θ value	1.38821 (rank : 236)	NC score	0.222496 (rank : 87)
Query Neighborhood Hits	409	Target Neighborhood Hits	396	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYFB_HUMAN
θ value	1.38821 (rank : 237)	NC score	0.032697 (rank : 498)
Query Neighborhood Hits	409	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSD9, O95708, Q9NZZ6	Gene names	FARSLB, FARSB, FRSB
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

AOC2_MOUSE
θ value	1.81305 (rank : 238)	NC score	0.023335 (rank : 532)
Query Neighborhood Hits	409	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q812C9, Q80WP3	Gene names	Aoc2
Domain Architecture
Description	Retina-specific copper amine oxidase precursor (EC 1.4.3.6) (RAO) (Amine oxidase [copper-containing]).

AOC3_MOUSE
θ value	1.81305 (rank : 239)	NC score	0.023874 (rank : 524)
Query Neighborhood Hits	409	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	O70423, Q66JM4, Q9R055	Gene names	Aoc3, Vap1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1).

BI2L1_HUMAN
θ value	1.81305 (rank : 240)	NC score	0.063871 (rank : 315)
Query Neighborhood Hits	409	Target Neighborhood Hits	156	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BSN_MOUSE
θ value	1.81305 (rank : 241)	NC score	0.073099 (rank : 270)
Query Neighborhood Hits	409	Target Neighborhood Hits	2057	Shared Neighborhood Hits	180
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CN037_MOUSE
θ value	1.81305 (rank : 242)	NC score	0.025693 (rank : 516)
Query Neighborhood Hits	409	Target Neighborhood Hits	179	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

COA2_HUMAN
θ value	1.81305 (rank : 243)	NC score	0.023627 (rank : 525)
Query Neighborhood Hits	409	Target Neighborhood Hits	184	Shared Neighborhood Hits	24
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

INVS_MOUSE
θ value	1.81305 (rank : 244)	NC score	0.017061 (rank : 560)
Query Neighborhood Hits	409	Target Neighborhood Hits	609	Shared Neighborhood Hits	53
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

IQEC2_HUMAN
θ value	1.81305 (rank : 245)	NC score	0.036606 (rank : 479)
Query Neighborhood Hits	409	Target Neighborhood Hits	403	Shared Neighborhood Hits	69
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	1.81305 (rank : 246)	NC score	0.036474 (rank : 481)
Query Neighborhood Hits	409	Target Neighborhood Hits	417	Shared Neighborhood Hits	70
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

MATK_MOUSE
θ value	1.81305 (rank : 247)	NC score	0.021815 (rank : 540)
Query Neighborhood Hits	409	Target Neighborhood Hits	952	Shared Neighborhood Hits	62
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

PACN1_HUMAN
θ value	1.81305 (rank : 248)	NC score	0.163100 (rank : 141)
Query Neighborhood Hits	409	Target Neighborhood Hits	320	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_MOUSE
θ value	1.81305 (rank : 249)	NC score	0.164589 (rank : 140)
Query Neighborhood Hits	409	Target Neighborhood Hits	283	Shared Neighborhood Hits	118
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

RTN1_MOUSE
θ value	1.81305 (rank : 250)	NC score	0.024506 (rank : 519)
Query Neighborhood Hits	409	Target Neighborhood Hits	189	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

RUSC1_MOUSE
θ value	1.81305 (rank : 251)	NC score	0.122737 (rank : 173)
Query Neighborhood Hits	409	Target Neighborhood Hits	206	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SAPS1_HUMAN
θ value	1.81305 (rank : 252)	NC score	0.045837 (rank : 443)
Query Neighborhood Hits	409	Target Neighborhood Hits	704	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEM6B_MOUSE
θ value	1.81305 (rank : 253)	NC score	0.010412 (rank : 582)
Query Neighborhood Hits	409	Target Neighborhood Hits	200	Shared Neighborhood Hits	43
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SH3G3_MOUSE
θ value	1.81305 (rank : 254)	NC score	0.177574 (rank : 129)
Query Neighborhood Hits	409	Target Neighborhood Hits	236	Shared Neighborhood Hits	113
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

SOX13_MOUSE
θ value	1.81305 (rank : 255)	NC score	0.023525 (rank : 528)
Query Neighborhood Hits	409	Target Neighborhood Hits	495	Shared Neighborhood Hits	50
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX30_HUMAN
θ value	1.81305 (rank : 256)	NC score	0.020822 (rank : 544)
Query Neighborhood Hits	409	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

STIM2_HUMAN
θ value	1.81305 (rank : 257)	NC score	0.021120 (rank : 542)
Query Neighborhood Hits	409	Target Neighborhood Hits	420	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

ABI1_HUMAN
θ value	2.36792 (rank : 258)	NC score	0.198395 (rank : 111)
Query Neighborhood Hits	409	Target Neighborhood Hits	257	Shared Neighborhood Hits	136
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

ARHG1_MOUSE
θ value	2.36792 (rank : 259)	NC score	0.063133 (rank : 324)
Query Neighborhood Hits	409	Target Neighborhood Hits	266	Shared Neighborhood Hits	55
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHGG_MOUSE
θ value	2.36792 (rank : 260)	NC score	0.115132 (rank : 179)
Query Neighborhood Hits	409	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ASPP2_HUMAN
θ value	2.36792 (rank : 261)	NC score	0.105864 (rank : 191)
Query Neighborhood Hits	409	Target Neighborhood Hits	1156	Shared Neighborhood Hits	150
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

BSN_HUMAN
θ value	2.36792 (rank : 262)	NC score	0.061910 (rank : 333)
Query Neighborhood Hits	409	Target Neighborhood Hits	1537	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CC040_HUMAN
θ value	2.36792 (rank : 263)	NC score	0.024946 (rank : 518)
Query Neighborhood Hits	409	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXB0, Q8TA84	Gene names	C3orf40
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf40 precursor.

CO1A2_MOUSE
θ value	2.36792 (rank : 264)	NC score	0.041687 (rank : 456)
Query Neighborhood Hits	409	Target Neighborhood Hits	388	Shared Neighborhood Hits	69
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

DLG4_HUMAN
θ value	2.36792 (rank : 265)	NC score	0.023445 (rank : 529)
Query Neighborhood Hits	409	Target Neighborhood Hits	286	Shared Neighborhood Hits	55
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	2.36792 (rank : 266)	NC score	0.021949 (rank : 538)
Query Neighborhood Hits	409	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DOCK1_HUMAN
θ value	2.36792 (rank : 267)	NC score	0.059683 (rank : 352)
Query Neighborhood Hits	409	Target Neighborhood Hits	191	Shared Neighborhood Hits	83
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

DOT1L_HUMAN
θ value	2.36792 (rank : 268)	NC score	0.060344 (rank : 347)
Query Neighborhood Hits	409	Target Neighborhood Hits	660	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EHMT2_MOUSE
θ value	2.36792 (rank : 269)	NC score	0.024177 (rank : 521)
Query Neighborhood Hits	409	Target Neighborhood Hits	750	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EPS8_HUMAN
θ value	2.36792 (rank : 270)	NC score	0.064013 (rank : 313)
Query Neighborhood Hits	409	Target Neighborhood Hits	151	Shared Neighborhood Hits	79
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

RGP1_HUMAN
θ value	2.36792 (rank : 271)	NC score	0.023580 (rank : 526)
Query Neighborhood Hits	409	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

SH3G2_HUMAN
θ value	2.36792 (rank : 272)	NC score	0.184191 (rank : 123)
Query Neighborhood Hits	409	Target Neighborhood Hits	324	Shared Neighborhood Hits	122
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SH3G3_HUMAN
θ value	2.36792 (rank : 273)	NC score	0.176605 (rank : 131)
Query Neighborhood Hits	409	Target Neighborhood Hits	222	Shared Neighborhood Hits	113
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SRBS1_MOUSE
θ value	2.36792 (rank : 274)	NC score	0.222305 (rank : 88)
Query Neighborhood Hits	409	Target Neighborhood Hits	409	Shared Neighborhood Hits	143
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

TARA_HUMAN
θ value	2.36792 (rank : 275)	NC score	0.033836 (rank : 493)
Query Neighborhood Hits	409	Target Neighborhood Hits	1626	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

THSD1_MOUSE
θ value	2.36792 (rank : 276)	NC score	0.013055 (rank : 576)
Query Neighborhood Hits	409	Target Neighborhood Hits	153	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TLE1_MOUSE
θ value	2.36792 (rank : 277)	NC score	0.011706 (rank : 578)
Query Neighborhood Hits	409	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ZN263_HUMAN
θ value	2.36792 (rank : 278)	NC score	-0.005812 (rank : 619)
Query Neighborhood Hits	409	Target Neighborhood Hits	795	Shared Neighborhood Hits	17
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

ZN414_HUMAN
θ value	2.36792 (rank : 279)	NC score	0.025509 (rank : 517)
Query Neighborhood Hits	409	Target Neighborhood Hits	548	Shared Neighborhood Hits	34
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

ACK1_HUMAN
θ value	3.0926 (rank : 280)	NC score	0.013751 (rank : 574)
Query Neighborhood Hits	409	Target Neighborhood Hits	1140	Shared Neighborhood Hits	101
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	3.0926 (rank : 281)	NC score	0.014352 (rank : 572)
Query Neighborhood Hits	409	Target Neighborhood Hits	1080	Shared Neighborhood Hits	106
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

CO5A1_HUMAN
θ value	3.0926 (rank : 282)	NC score	0.041626 (rank : 457)
Query Neighborhood Hits	409	Target Neighborhood Hits	434	Shared Neighborhood Hits	77
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

COHA1_HUMAN
θ value	3.0926 (rank : 283)	NC score	0.040016 (rank : 465)
Query Neighborhood Hits	409	Target Neighborhood Hits	400	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DCP1A_HUMAN
θ value	3.0926 (rank : 284)	NC score	0.022427 (rank : 535)
Query Neighborhood Hits	409	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DLX4_MOUSE
θ value	3.0926 (rank : 285)	NC score	0.003413 (rank : 604)
Query Neighborhood Hits	409	Target Neighborhood Hits	352	Shared Neighborhood Hits	12
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

EDN3_HUMAN
θ value	3.0926 (rank : 286)	NC score	0.016362 (rank : 564)
Query Neighborhood Hits	409	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

ISL1_HUMAN
θ value	3.0926 (rank : 287)	NC score	0.003353 (rank : 605)
Query Neighborhood Hits	409	Target Neighborhood Hits	421	Shared Neighborhood Hits	13
SwissProt Accessions	P61371, P20663, P47894	Gene names	ISL1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

ISL1_MOUSE
θ value	3.0926 (rank : 288)	NC score	0.003353 (rank : 606)
Query Neighborhood Hits	409	Target Neighborhood Hits	421	Shared Neighborhood Hits	13
SwissProt Accessions	P61372, P20663, P47894, Q812D8	Gene names	Isl1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

MAP1A_HUMAN
θ value	3.0926 (rank : 289)	NC score	0.033574 (rank : 494)
Query Neighborhood Hits	409	Target Neighborhood Hits	1626	Shared Neighborhood Hits	111
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MISS_MOUSE
θ value	3.0926 (rank : 290)	NC score	0.065779 (rank : 303)
Query Neighborhood Hits	409	Target Neighborhood Hits	444	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NCOA6_HUMAN
θ value	3.0926 (rank : 291)	NC score	0.063964 (rank : 314)
Query Neighborhood Hits	409	Target Neighborhood Hits	1202	Shared Neighborhood Hits	139
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NKX26_MOUSE
θ value	3.0926 (rank : 292)	NC score	0.000969 (rank : 610)
Query Neighborhood Hits	409	Target Neighborhood Hits	343	Shared Neighborhood Hits	11
SwissProt Accessions	P43688	Gene names	Nkx2-6, Nkx-2.6, Nkx2f
Domain Architecture
Description	Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F).

NKX31_MOUSE
θ value	3.0926 (rank : 293)	NC score	0.001200 (rank : 608)
Query Neighborhood Hits	409	Target Neighborhood Hits	379	Shared Neighborhood Hits	15
SwissProt Accessions	P97436, O09087	Gene names	Nkx3-1, Nkx-3.1, Nkx3a
Domain Architecture
Description	Homeobox protein Nkx-3.1.

NUP53_HUMAN
θ value	3.0926 (rank : 294)	NC score	0.032063 (rank : 500)
Query Neighborhood Hits	409	Target Neighborhood Hits	156	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

PEX14_MOUSE
θ value	3.0926 (rank : 295)	NC score	0.035349 (rank : 485)
Query Neighborhood Hits	409	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

PLXB1_HUMAN
θ value	3.0926 (rank : 296)	NC score	0.019460 (rank : 546)
Query Neighborhood Hits	409	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

SFR15_HUMAN
θ value	3.0926 (rank : 297)	NC score	0.072611 (rank : 274)
Query Neighborhood Hits	409	Target Neighborhood Hits	368	Shared Neighborhood Hits	69
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SH22A_HUMAN
θ value	3.0926 (rank : 298)	NC score	0.051598 (rank : 417)
Query Neighborhood Hits	409	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SMCA2_HUMAN
θ value	3.0926 (rank : 299)	NC score	0.016458 (rank : 562)
Query Neighborhood Hits	409	Target Neighborhood Hits	503	Shared Neighborhood Hits	58
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

VGLL4_HUMAN
θ value	3.0926 (rank : 300)	NC score	0.017409 (rank : 558)
Query Neighborhood Hits	409	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q14135, Q7L5V0, Q9BQ78	Gene names	VGLL4, KIAA0121
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 4 (Vgl-4).

ABI3_MOUSE
θ value	4.03905 (rank : 301)	NC score	0.173321 (rank : 134)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AMOL1_MOUSE
θ value	4.03905 (rank : 302)	NC score	0.008991 (rank : 587)
Query Neighborhood Hits	409	Target Neighborhood Hits	445	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

ATOH1_HUMAN
θ value	4.03905 (rank : 303)	NC score	0.010812 (rank : 581)
Query Neighborhood Hits	409	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

CASL_HUMAN
θ value	4.03905 (rank : 304)	NC score	0.142848 (rank : 154)
Query Neighborhood Hits	409	Target Neighborhood Hits	259	Shared Neighborhood Hits	118
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CO4A2_MOUSE
θ value	4.03905 (rank : 305)	NC score	0.027623 (rank : 512)
Query Neighborhood Hits	409	Target Neighborhood Hits	492	Shared Neighborhood Hits	66
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A4_HUMAN
θ value	4.03905 (rank : 306)	NC score	0.038901 (rank : 470)
Query Neighborhood Hits	409	Target Neighborhood Hits	440	Shared Neighborhood Hits	82
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CSKI2_MOUSE
θ value	4.03905 (rank : 307)	NC score	0.059037 (rank : 357)
Query Neighborhood Hits	409	Target Neighborhood Hits	812	Shared Neighborhood Hits	126
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DDEF2_HUMAN
θ value	4.03905 (rank : 308)	NC score	0.134639 (rank : 161)
Query Neighborhood Hits	409	Target Neighborhood Hits	599	Shared Neighborhood Hits	143
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	4.03905 (rank : 309)	NC score	0.139884 (rank : 156)
Query Neighborhood Hits	409	Target Neighborhood Hits	625	Shared Neighborhood Hits	154
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DUET_HUMAN
θ value	4.03905 (rank : 310)	NC score	0.023353 (rank : 531)
Query Neighborhood Hits	409	Target Neighborhood Hits	1220	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

K0329_HUMAN
θ value	4.03905 (rank : 311)	NC score	0.027537 (rank : 513)
Query Neighborhood Hits	409	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

MATK_HUMAN
θ value	4.03905 (rank : 312)	NC score	0.021089 (rank : 543)
Query Neighborhood Hits	409	Target Neighborhood Hits	954	Shared Neighborhood Hits	57
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MILK2_HUMAN
θ value	4.03905 (rank : 313)	NC score	0.034345 (rank : 491)
Query Neighborhood Hits	409	Target Neighborhood Hits	457	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

NALP1_HUMAN
θ value	4.03905 (rank : 314)	NC score	0.005584 (rank : 602)
Query Neighborhood Hits	409	Target Neighborhood Hits	138	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

PP1RA_HUMAN
θ value	4.03905 (rank : 315)	NC score	0.048742 (rank : 439)
Query Neighborhood Hits	409	Target Neighborhood Hits	180	Shared Neighborhood Hits	46
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

RNF25_HUMAN
θ value	4.03905 (rank : 316)	NC score	0.018029 (rank : 551)
Query Neighborhood Hits	409	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

SH3G1_MOUSE
θ value	4.03905 (rank : 317)	NC score	0.175919 (rank : 132)
Query Neighborhood Hits	409	Target Neighborhood Hits	291	Shared Neighborhood Hits	116
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SSBP4_HUMAN
θ value	4.03905 (rank : 318)	NC score	0.048528 (rank : 440)
Query Neighborhood Hits	409	Target Neighborhood Hits	753	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TAOK2_MOUSE
θ value	4.03905 (rank : 319)	NC score	0.001052 (rank : 609)
Query Neighborhood Hits	409	Target Neighborhood Hits	1373	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

TAU_MOUSE
θ value	4.03905 (rank : 320)	NC score	0.042501 (rank : 453)
Query Neighborhood Hits	409	Target Neighborhood Hits	502	Shared Neighborhood Hits	73
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CING_HUMAN
θ value	5.27518 (rank : 321)	NC score	0.009431 (rank : 586)
Query Neighborhood Hits	409	Target Neighborhood Hits	1275	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CJ012_HUMAN
θ value	5.27518 (rank : 322)	NC score	0.019090 (rank : 547)
Query Neighborhood Hits	409	Target Neighborhood Hits	467	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CN032_HUMAN
θ value	5.27518 (rank : 323)	NC score	0.108716 (rank : 188)
Query Neighborhood Hits	409	Target Neighborhood Hits	267	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

COAA1_HUMAN
θ value	5.27518 (rank : 324)	NC score	0.035124 (rank : 487)
Query Neighborhood Hits	409	Target Neighborhood Hits	316	Shared Neighborhood Hits	64
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COBA1_HUMAN
θ value	5.27518 (rank : 325)	NC score	0.037710 (rank : 475)
Query Neighborhood Hits	409	Target Neighborhood Hits	491	Shared Neighborhood Hits	76
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COHA1_MOUSE
θ value	5.27518 (rank : 326)	NC score	0.044023 (rank : 449)
Query Neighborhood Hits	409	Target Neighborhood Hits	414	Shared Neighborhood Hits	75
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

EHMT2_HUMAN
θ value	5.27518 (rank : 327)	NC score	0.014714 (rank : 571)
Query Neighborhood Hits	409	Target Neighborhood Hits	498	Shared Neighborhood Hits	36
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

GLR_MOUSE
θ value	5.27518 (rank : 328)	NC score	0.006461 (rank : 598)
Query Neighborhood Hits	409	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

GP157_MOUSE
θ value	5.27518 (rank : 329)	NC score	0.009843 (rank : 584)
Query Neighborhood Hits	409	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GR65_HUMAN
θ value	5.27518 (rank : 330)	NC score	0.026772 (rank : 515)
Query Neighborhood Hits	409	Target Neighborhood Hits	148	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

GRIN1_MOUSE
θ value	5.27518 (rank : 331)	NC score	0.038613 (rank : 472)
Query Neighborhood Hits	409	Target Neighborhood Hits	337	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HES7_MOUSE
θ value	5.27518 (rank : 332)	NC score	0.013470 (rank : 575)
Query Neighborhood Hits	409	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HXD1_MOUSE
θ value	5.27518 (rank : 333)	NC score	-0.000489 (rank : 614)
Query Neighborhood Hits	409	Target Neighborhood Hits	381	Shared Neighborhood Hits	13
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

IF4B_HUMAN
θ value	5.27518 (rank : 334)	NC score	0.017706 (rank : 554)
Query Neighborhood Hits	409	Target Neighborhood Hits	417	Shared Neighborhood Hits	36
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4B_MOUSE
θ value	5.27518 (rank : 335)	NC score	0.017990 (rank : 553)
Query Neighborhood Hits	409	Target Neighborhood Hits	368	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

KLF13_MOUSE
θ value	5.27518 (rank : 336)	NC score	-0.004059 (rank : 618)
Query Neighborhood Hits	409	Target Neighborhood Hits	757	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

NRX2A_HUMAN
θ value	5.27518 (rank : 337)	NC score	0.024456 (rank : 520)
Query Neighborhood Hits	409	Target Neighborhood Hits	614	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	5.27518 (rank : 338)	NC score	0.039553 (rank : 466)
Query Neighborhood Hits	409	Target Neighborhood Hits	481	Shared Neighborhood Hits	86
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PDZD2_HUMAN
θ value	5.27518 (rank : 339)	NC score	0.036374 (rank : 482)
Query Neighborhood Hits	409	Target Neighborhood Hits	772	Shared Neighborhood Hits	81
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PI5PA_MOUSE
θ value	5.27518 (rank : 340)	NC score	0.080790 (rank : 247)
Query Neighborhood Hits	409	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RFIP1_MOUSE
θ value	5.27518 (rank : 341)	NC score	0.021278 (rank : 541)
Query Neighborhood Hits	409	Target Neighborhood Hits	152	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SETB1_MOUSE
θ value	5.27518 (rank : 342)	NC score	0.017337 (rank : 559)
Query Neighborhood Hits	409	Target Neighborhood Hits	150	Shared Neighborhood Hits	26
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SOX30_MOUSE
θ value	5.27518 (rank : 343)	NC score	0.022766 (rank : 534)
Query Neighborhood Hits	409	Target Neighborhood Hits	374	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

STON2_HUMAN
θ value	5.27518 (rank : 344)	NC score	0.028273 (rank : 508)
Query Neighborhood Hits	409	Target Neighborhood Hits	115	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

SYFB_MOUSE
θ value	5.27518 (rank : 345)	NC score	0.024091 (rank : 523)
Query Neighborhood Hits	409	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUA2	Gene names	Farslb, Farsb, Farsl, Frsb
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

TCRG1_MOUSE
θ value	5.27518 (rank : 346)	NC score	0.069890 (rank : 282)
Query Neighborhood Hits	409	Target Neighborhood Hits	947	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TLE1_HUMAN
θ value	5.27518 (rank : 347)	NC score	0.009618 (rank : 585)
Query Neighborhood Hits	409	Target Neighborhood Hits	485	Shared Neighborhood Hits	49
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

ZDHC1_HUMAN
θ value	5.27518 (rank : 348)	NC score	0.019648 (rank : 545)
Query Neighborhood Hits	409	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

ADA12_MOUSE
θ value	6.88961 (rank : 349)	NC score	0.007920 (rank : 591)
Query Neighborhood Hits	409	Target Neighborhood Hits	474	Shared Neighborhood Hits	47
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA19_HUMAN
θ value	6.88961 (rank : 350)	NC score	0.005415 (rank : 603)
Query Neighborhood Hits	409	Target Neighborhood Hits	381	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

BIN1_HUMAN
θ value	6.88961 (rank : 351)	NC score	0.063551 (rank : 317)
Query Neighborhood Hits	409	Target Neighborhood Hits	335	Shared Neighborhood Hits	90
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

BIN1_MOUSE
θ value	6.88961 (rank : 352)	NC score	0.069601 (rank : 286)
Query Neighborhood Hits	409	Target Neighborhood Hits	283	Shared Neighborhood Hits	86
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CABIN_HUMAN
θ value	6.88961 (rank : 353)	NC score	0.054997 (rank : 384)
Query Neighborhood Hits	409	Target Neighborhood Hits	490	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CNTRB_MOUSE
θ value	6.88961 (rank : 354)	NC score	0.018687 (rank : 548)
Query Neighborhood Hits	409	Target Neighborhood Hits	1029	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO2A1_HUMAN
θ value	6.88961 (rank : 355)	NC score	0.033550 (rank : 495)
Query Neighborhood Hits	409	Target Neighborhood Hits	486	Shared Neighborhood Hits	77
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_MOUSE
θ value	6.88961 (rank : 356)	NC score	0.032893 (rank : 497)
Query Neighborhood Hits	409	Target Neighborhood Hits	483	Shared Neighborhood Hits	72
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

COFA1_HUMAN
θ value	6.88961 (rank : 357)	NC score	0.037410 (rank : 476)
Query Neighborhood Hits	409	Target Neighborhood Hits	292	Shared Neighborhood Hits	52
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

CRSP2_HUMAN
θ value	6.88961 (rank : 358)	NC score	0.034638 (rank : 490)
Query Neighborhood Hits	409	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CSKI2_HUMAN
θ value	6.88961 (rank : 359)	NC score	0.060522 (rank : 346)
Query Neighborhood Hits	409	Target Neighborhood Hits	747	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DEN1A_HUMAN
θ value	6.88961 (rank : 360)	NC score	0.023545 (rank : 527)
Query Neighborhood Hits	409	Target Neighborhood Hits	176	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

EFS_HUMAN
θ value	6.88961 (rank : 361)	NC score	0.162475 (rank : 142)
Query Neighborhood Hits	409	Target Neighborhood Hits	348	Shared Neighborhood Hits	141
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FMNL_MOUSE
θ value	6.88961 (rank : 362)	NC score	0.059351 (rank : 355)
Query Neighborhood Hits	409	Target Neighborhood Hits	428	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

GASP1_MOUSE
θ value	6.88961 (rank : 363)	NC score	0.006303 (rank : 600)
Query Neighborhood Hits	409	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

HCN2_HUMAN
θ value	6.88961 (rank : 364)	NC score	0.023199 (rank : 533)
Query Neighborhood Hits	409	Target Neighborhood Hits	369	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

K2027_HUMAN
θ value	6.88961 (rank : 365)	NC score	0.018420 (rank : 550)
Query Neighborhood Hits	409	Target Neighborhood Hits	194	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

LYN_MOUSE
θ value	6.88961 (rank : 366)	NC score	0.029355 (rank : 506)
Query Neighborhood Hits	409	Target Neighborhood Hits	1023	Shared Neighborhood Hits	110
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MAP2_HUMAN
θ value	6.88961 (rank : 367)	NC score	0.018675 (rank : 549)
Query Neighborhood Hits	409	Target Neighborhood Hits	348	Shared Neighborhood Hits	35
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MICA1_HUMAN
θ value	6.88961 (rank : 368)	NC score	0.011077 (rank : 580)
Query Neighborhood Hits	409	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MINT_HUMAN
θ value	6.88961 (rank : 369)	NC score	0.035847 (rank : 484)
Query Neighborhood Hits	409	Target Neighborhood Hits	1291	Shared Neighborhood Hits	96
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
θ value	6.88961 (rank : 370)	NC score	0.044889 (rank : 448)
Query Neighborhood Hits	409	Target Neighborhood Hits	1514	Shared Neighborhood Hits	123
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MSX1_HUMAN
θ value	6.88961 (rank : 371)	NC score	-0.000416 (rank : 613)
Query Neighborhood Hits	409	Target Neighborhood Hits	374	Shared Neighborhood Hits	18
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

NETR_HUMAN
θ value	6.88961 (rank : 372)	NC score	-0.003963 (rank : 617)
Query Neighborhood Hits	409	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NU214_HUMAN
θ value	6.88961 (rank : 373)	NC score	0.050104 (rank : 437)
Query Neighborhood Hits	409	Target Neighborhood Hits	657	Shared Neighborhood Hits	76
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PCLO_MOUSE
θ value	6.88961 (rank : 374)	NC score	0.072552 (rank : 275)
Query Neighborhood Hits	409	Target Neighborhood Hits	2275	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PER3_HUMAN
θ value	6.88961 (rank : 375)	NC score	0.024159 (rank : 522)
Query Neighborhood Hits	409	Target Neighborhood Hits	479	Shared Neighborhood Hits	64
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PP1RA_MOUSE
θ value	6.88961 (rank : 376)	NC score	0.034965 (rank : 488)
Query Neighborhood Hits	409	Target Neighborhood Hits	175	Shared Neighborhood Hits	39
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

RIMB1_MOUSE
θ value	6.88961 (rank : 377)	NC score	0.060800 (rank : 343)
Query Neighborhood Hits	409	Target Neighborhood Hits	1376	Shared Neighborhood Hits	148
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TAF6L_MOUSE
θ value	6.88961 (rank : 378)	NC score	0.013994 (rank : 573)
Query Neighborhood Hits	409	Target Neighborhood Hits	146	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TARSH_HUMAN
θ value	6.88961 (rank : 379)	NC score	0.058103 (rank : 363)
Query Neighborhood Hits	409	Target Neighborhood Hits	768	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TIAM1_HUMAN
θ value	6.88961 (rank : 380)	NC score	0.105839 (rank : 192)
Query Neighborhood Hits	409	Target Neighborhood Hits	225	Shared Neighborhood Hits	42
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

YLPM1_HUMAN
θ value	6.88961 (rank : 381)	NC score	0.070051 (rank : 280)
Query Neighborhood Hits	409	Target Neighborhood Hits	670	Shared Neighborhood Hits	94
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ABI3_HUMAN
θ value	8.99809 (rank : 382)	NC score	0.167869 (rank : 136)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	117
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

BAI2_HUMAN
θ value	8.99809 (rank : 383)	NC score	0.005871 (rank : 601)
Query Neighborhood Hits	409	Target Neighborhood Hits	332	Shared Neighborhood Hits	21
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CAC1B_MOUSE
θ value	8.99809 (rank : 384)	NC score	0.007445 (rank : 592)
Query Neighborhood Hits	409	Target Neighborhood Hits	351	Shared Neighborhood Hits	37
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CEP41_HUMAN
θ value	8.99809 (rank : 385)	NC score	0.015047 (rank : 569)
Query Neighborhood Hits	409	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYV8, Q7Z496, Q86TM1, Q8NFU8, Q9H6A3, Q9NPV3	Gene names	TSGA14, CEP41
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

CO1A1_HUMAN
θ value	8.99809 (rank : 386)	NC score	0.043538 (rank : 452)
Query Neighborhood Hits	409	Target Neighborhood Hits	475	Shared Neighborhood Hits	83
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_MOUSE
θ value	8.99809 (rank : 387)	NC score	0.043583 (rank : 451)
Query Neighborhood Hits	409	Target Neighborhood Hits	466	Shared Neighborhood Hits	76
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO5A1_MOUSE
θ value	8.99809 (rank : 388)	NC score	0.041193 (rank : 460)
Query Neighborhood Hits	409	Target Neighborhood Hits	419	Shared Neighborhood Hits	73
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CO5A2_HUMAN
θ value	8.99809 (rank : 389)	NC score	0.033331 (rank : 496)
Query Neighborhood Hits	409	Target Neighborhood Hits	760	Shared Neighborhood Hits	87
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CSKI1_HUMAN
θ value	8.99809 (rank : 390)	NC score	0.051401 (rank : 419)
Query Neighborhood Hits	409	Target Neighborhood Hits	997	Shared Neighborhood Hits	154
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKP_HUMAN
θ value	8.99809 (rank : 391)	NC score	0.012019 (rank : 577)
Query Neighborhood Hits	409	Target Neighborhood Hits	1022	Shared Neighborhood Hits	84
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	8.99809 (rank : 392)	NC score	0.011290 (rank : 579)
Query Neighborhood Hits	409	Target Neighborhood Hits	1027	Shared Neighborhood Hits	88
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

DUS2L_HUMAN
θ value	8.99809 (rank : 393)	NC score	0.015875 (rank : 565)
Query Neighborhood Hits	409	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NX74, Q4H4D9	Gene names	DUS2L, DUS2
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 2-like (EC 1.-.-.-) (hDUS2) (Up-regulated in lung cancer) (URLC8).

EFS_MOUSE
θ value	8.99809 (rank : 394)	NC score	0.157451 (rank : 145)
Query Neighborhood Hits	409	Target Neighborhood Hits	389	Shared Neighborhood Hits	149
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

FOXH1_HUMAN
θ value	8.99809 (rank : 395)	NC score	0.008325 (rank : 589)
Query Neighborhood Hits	409	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

HGS_MOUSE
θ value	8.99809 (rank : 396)	NC score	0.036067 (rank : 483)
Query Neighborhood Hits	409	Target Neighborhood Hits	589	Shared Neighborhood Hits	58
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

LYN_HUMAN
θ value	8.99809 (rank : 397)	NC score	0.029672 (rank : 504)
Query Neighborhood Hits	409	Target Neighborhood Hits	1022	Shared Neighborhood Hits	112
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MLL2_HUMAN
θ value	8.99809 (rank : 398)	NC score	0.068091 (rank : 293)
Query Neighborhood Hits	409	Target Neighborhood Hits	1788	Shared Neighborhood Hits	178
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYO15_HUMAN
θ value	8.99809 (rank : 399)	NC score	0.063286 (rank : 321)
Query Neighborhood Hits	409	Target Neighborhood Hits	671	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NPBL_MOUSE
θ value	8.99809 (rank : 400)	NC score	0.017655 (rank : 556)
Query Neighborhood Hits	409	Target Neighborhood Hits	1041	Shared Neighborhood Hits	62
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PANK1_HUMAN
θ value	8.99809 (rank : 401)	NC score	0.007236 (rank : 593)
Query Neighborhood Hits	409	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

PRR3_HUMAN
θ value	8.99809 (rank : 402)	NC score	0.016423 (rank : 563)
Query Neighborhood Hits	409	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	P79522, Q5RJB5	Gene names	PRR3, CAT56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

RBM15_HUMAN
θ value	8.99809 (rank : 403)	NC score	0.008813 (rank : 588)
Query Neighborhood Hits	409	Target Neighborhood Hits	309	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

RGL2_HUMAN
θ value	8.99809 (rank : 404)	NC score	0.010208 (rank : 583)
Query Neighborhood Hits	409	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

S23IP_MOUSE
θ value	8.99809 (rank : 405)	NC score	0.038541 (rank : 473)
Query Neighborhood Hits	409	Target Neighborhood Hits	363	Shared Neighborhood Hits	53
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SFPQ_MOUSE
θ value	8.99809 (rank : 406)	NC score	0.057718 (rank : 367)
Query Neighborhood Hits	409	Target Neighborhood Hits	958	Shared Neighborhood Hits	116
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SPR1B_MOUSE
θ value	8.99809 (rank : 407)	NC score	0.026884 (rank : 514)
Query Neighborhood Hits	409	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

TS1R1_HUMAN
θ value	8.99809 (rank : 408)	NC score	0.000891 (rank : 611)
Query Neighborhood Hits	409	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TTC16_HUMAN
θ value	8.99809 (rank : 409)	NC score	0.007153 (rank : 594)
Query Neighborhood Hits	409	Target Neighborhood Hits	417	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

AB1IP_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.052538 (rank : 406)
Query Neighborhood Hits	409	Target Neighborhood Hits	213	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ALEX_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.059772 (rank : 350)
Query Neighborhood Hits	409	Target Neighborhood Hits	197	Shared Neighborhood Hits	47
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AMPH_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.065744 (rank : 304)
Query Neighborhood Hits	409	Target Neighborhood Hits	455	Shared Neighborhood Hits	101
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AMPH_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.060856 (rank : 342)
Query Neighborhood Hits	409	Target Neighborhood Hits	291	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

ANM2_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.104306 (rank : 193)
Query Neighborhood Hits	409	Target Neighborhood Hits	175	Shared Neighborhood Hits	94
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ANM2_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.103061 (rank : 196)
Query Neighborhood Hits	409	Target Neighborhood Hits	175	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

ARHG1_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.067719 (rank : 296)
Query Neighborhood Hits	409	Target Neighborhood Hits	176	Shared Neighborhood Hits	48
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHG2_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.060954 (rank : 340)
Query Neighborhood Hits	409	Target Neighborhood Hits	142	Shared Neighborhood Hits	35
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

ARHG2_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.059376 (rank : 353)
Query Neighborhood Hits	409	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

ARHG3_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.091769 (rank : 216)
Query Neighborhood Hits	409	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG3_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.091059 (rank : 220)
Query Neighborhood Hits	409	Target Neighborhood Hits	85	Shared Neighborhood Hits	31
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

ARHG5_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.109594 (rank : 185)
Query Neighborhood Hits	409	Target Neighborhood Hits	172	Shared Neighborhood Hits	76
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

ARHG8_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.088799 (rank : 226)
Query Neighborhood Hits	409	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHG8_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.091706 (rank : 217)
Query Neighborhood Hits	409	Target Neighborhood Hits	79	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

ARHGA_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.094530 (rank : 211)
Query Neighborhood Hits	409	Target Neighborhood Hits	187	Shared Neighborhood Hits	33
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGA_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.092965 (rank : 214)
Query Neighborhood Hits	409	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ARHGB_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.066839 (rank : 297)
Query Neighborhood Hits	409	Target Neighborhood Hits	375	Shared Neighborhood Hits	49
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ARHGC_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.062048 (rank : 332)
Query Neighborhood Hits	409	Target Neighborhood Hits	351	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.060696 (rank : 345)
Query Neighborhood Hits	409	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGF_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.088355 (rank : 227)
Query Neighborhood Hits	409	Target Neighborhood Hits	214	Shared Neighborhood Hits	61
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ARI1A_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.050985 (rank : 425)
Query Neighborhood Hits	409	Target Neighborhood Hits	787	Shared Neighborhood Hits	110
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ARI1B_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.051384 (rank : 420)
Query Neighborhood Hits	409	Target Neighborhood Hits	567	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ATN1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.073073 (rank : 271)
Query Neighborhood Hits	409	Target Neighborhood Hits	676	Shared Neighborhood Hits	102
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.098647 (rank : 204)
Query Neighborhood Hits	409	Target Neighborhood Hits	931	Shared Neighborhood Hits	140
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.063343 (rank : 319)
Query Neighborhood Hits	409	Target Neighborhood Hits	518	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BCL9_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.064189 (rank : 312)
Query Neighborhood Hits	409	Target Neighborhood Hits	770	Shared Neighborhood Hits	125
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BI2L1_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.050161 (rank : 436)
Query Neighborhood Hits	409	Target Neighborhood Hits	197	Shared Neighborhood Hits	49
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CASL_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.135811 (rank : 160)
Query Neighborhood Hits	409	Target Neighborhood Hits	225	Shared Neighborhood Hits	113
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CCD1A_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.052666 (rank : 403)
Query Neighborhood Hits	409	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

CCNK_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.059280 (rank : 356)
Query Neighborhood Hits	409	Target Neighborhood Hits	350	Shared Neighborhood Hits	71
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CENA2_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.051406 (rank : 418)
Query Neighborhood Hits	409	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.075695 (rank : 262)
Query Neighborhood Hits	409	Target Neighborhood Hits	383	Shared Neighborhood Hits	30
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.082312 (rank : 240)
Query Neighborhood Hits	409	Target Neighborhood Hits	425	Shared Neighborhood Hits	31
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.078551 (rank : 255)
Query Neighborhood Hits	409	Target Neighborhood Hits	395	Shared Neighborhood Hits	26
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENG1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.058613 (rank : 360)
Query Neighborhood Hits	409	Target Neighborhood Hits	544	Shared Neighborhood Hits	49
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.063175 (rank : 322)
Query Neighborhood Hits	409	Target Neighborhood Hits	531	Shared Neighborhood Hits	54
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CIC_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.060120 (rank : 348)
Query Neighborhood Hits	409	Target Neighborhood Hits	992	Shared Neighborhood Hits	136
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIP4_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.077269 (rank : 258)
Query Neighborhood Hits	409	Target Neighborhood Hits	374	Shared Neighborhood Hits	46
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CN032_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.110050 (rank : 184)
Query Neighborhood Hits	409	Target Neighborhood Hits	233	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.062406 (rank : 328)
Query Neighborhood Hits	409	Target Neighborhood Hits	385	Shared Neighborhood Hits	65
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CRK_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.154672 (rank : 148)
Query Neighborhood Hits	409	Target Neighborhood Hits	308	Shared Neighborhood Hits	121
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CRK_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.157359 (rank : 146)
Query Neighborhood Hits	409	Target Neighborhood Hits	314	Shared Neighborhood Hits	120
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CS016_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.068833 (rank : 290)
Query Neighborhood Hits	409	Target Neighborhood Hits	310	Shared Neighborhood Hits	63
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DAPP1_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.081910 (rank : 243)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.083767 (rank : 236)
Query Neighborhood Hits	409	Target Neighborhood Hits	225	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DBNL_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.142151 (rank : 155)
Query Neighborhood Hits	409	Target Neighborhood Hits	244	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.137571 (rank : 158)
Query Neighborhood Hits	409	Target Neighborhood Hits	306	Shared Neighborhood Hits	106
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DDEF1_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.129052 (rank : 164)
Query Neighborhood Hits	409	Target Neighborhood Hits	592	Shared Neighborhood Hits	133
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDFL1_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.060931 (rank : 341)
Query Neighborhood Hits	409	Target Neighborhood Hits	353	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.055417 (rank : 382)
Query Neighborhood Hits	409	Target Neighborhood Hits	324	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DGKH_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.051335 (rank : 421)
Query Neighborhood Hits	409	Target Neighborhood Hits	255	Shared Neighborhood Hits	30
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

ECT2_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.087964 (rank : 231)
Query Neighborhood Hits	409	Target Neighborhood Hits	98	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ECT2_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.088329 (rank : 228)
Query Neighborhood Hits	409	Target Neighborhood Hits	98	Shared Neighborhood Hits	30
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ENAH_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.082282 (rank : 241)
Query Neighborhood Hits	409	Target Neighborhood Hits	919	Shared Neighborhood Hits	109
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EPS8_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.063862 (rank : 316)
Query Neighborhood Hits	409	Target Neighborhood Hits	157	Shared Neighborhood Hits	83
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

ES8L1_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.050460 (rank : 431)
Query Neighborhood Hits	409	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L1_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.057287 (rank : 370)
Query Neighborhood Hits	409	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

ES8L2_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.054178 (rank : 388)
Query Neighborhood Hits	409	Target Neighborhood Hits	193	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L2_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.051333 (rank : 422)
Query Neighborhood Hits	409	Target Neighborhood Hits	169	Shared Neighborhood Hits	72
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

ES8L3_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.062650 (rank : 326)
Query Neighborhood Hits	409	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

ES8L3_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.074925 (rank : 265)
Query Neighborhood Hits	409	Target Neighborhood Hits	168	Shared Neighborhood Hits	85
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FA13A_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.062363 (rank : 329)
Query Neighborhood Hits	409	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.063139 (rank : 323)
Query Neighborhood Hits	409	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.052154 (rank : 408)
Query Neighborhood Hits	409	Target Neighborhood Hits	94	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FARP1_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.050920 (rank : 426)
Query Neighborhood Hits	409	Target Neighborhood Hits	241	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.054329 (rank : 386)
Query Neighborhood Hits	409	Target Neighborhood Hits	240	Shared Neighborhood Hits	44
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.057661 (rank : 369)
Query Neighborhood Hits	409	Target Neighborhood Hits	209	Shared Neighborhood Hits	42
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FGD1_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.078052 (rank : 256)
Query Neighborhood Hits	409	Target Neighborhood Hits	367	Shared Neighborhood Hits	73
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.072698 (rank : 273)
Query Neighborhood Hits	409	Target Neighborhood Hits	387	Shared Neighborhood Hits	84
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.065053 (rank : 308)
Query Neighborhood Hits	409	Target Neighborhood Hits	151	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.062071 (rank : 331)
Query Neighborhood Hits	409	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.064495 (rank : 311)
Query Neighborhood Hits	409	Target Neighborhood Hits	249	Shared Neighborhood Hits	42
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.069409 (rank : 288)
Query Neighborhood Hits	409	Target Neighborhood Hits	257	Shared Neighborhood Hits	39
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.068783 (rank : 291)
Query Neighborhood Hits	409	Target Neighborhood Hits	219	Shared Neighborhood Hits	38
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.069727 (rank : 284)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	38
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD6_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.058749 (rank : 359)
Query Neighborhood Hits	409	Target Neighborhood Hits	237	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.063307 (rank : 320)
Query Neighborhood Hits	409	Target Neighborhood Hits	282	Shared Neighborhood Hits	46
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FMN2_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.061161 (rank : 338)
Query Neighborhood Hits	409	Target Neighborhood Hits	484	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GGN_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.083886 (rank : 235)
Query Neighborhood Hits	409	Target Neighborhood Hits	269	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.085240 (rank : 233)
Query Neighborhood Hits	409	Target Neighborhood Hits	311	Shared Neighborhood Hits	71
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GNRP_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.076187 (rank : 261)
Query Neighborhood Hits	409	Target Neighborhood Hits	239	Shared Neighborhood Hits	35
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.081315 (rank : 246)
Query Neighborhood Hits	409	Target Neighborhood Hits	191	Shared Neighborhood Hits	33
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GRP3_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.095891 (rank : 208)
Query Neighborhood Hits	409	Target Neighborhood Hits	131	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.102446 (rank : 198)
Query Neighborhood Hits	409	Target Neighborhood Hits	674	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HAPIP_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.053154 (rank : 400)
Query Neighborhood Hits	409	Target Neighborhood Hits	350	Shared Neighborhood Hits	31
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

K1543_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.053183 (rank : 399)
Query Neighborhood Hits	409	Target Neighborhood Hits	435	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LASP1_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.122541 (rank : 174)
Query Neighborhood Hits	409	Target Neighborhood Hits	293	Shared Neighborhood Hits	109
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

LASP1_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.120655 (rank : 178)
Query Neighborhood Hits	409	Target Neighborhood Hits	297	Shared Neighborhood Hits	108
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

MBD6_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.112256 (rank : 182)
Query Neighborhood Hits	409	Target Neighborhood Hits	349	Shared Neighborhood Hits	81
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MCF2L_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.073763 (rank : 267)
Query Neighborhood Hits	409	Target Neighborhood Hits	255	Shared Neighborhood Hits	44
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

MCF2_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.076671 (rank : 260)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	32
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MDC1_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.056535 (rank : 374)
Query Neighborhood Hits	409	Target Neighborhood Hits	1446	Shared Neighborhood Hits	124
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.051808 (rank : 413)
Query Neighborhood Hits	409	Target Neighborhood Hits	998	Shared Neighborhood Hits	103
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MLL4_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.056432 (rank : 375)
Query Neighborhood Hits	409	Target Neighborhood Hits	722	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MUC7_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.091595 (rank : 218)
Query Neighborhood Hits	409	Target Neighborhood Hits	538	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MYO10_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.057875 (rank : 366)
Query Neighborhood Hits	409	Target Neighborhood Hits	920	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO15_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.061245 (rank : 337)
Query Neighborhood Hits	409	Target Neighborhood Hits	467	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO7A_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.050607 (rank : 429)
Query Neighborhood Hits	409	Target Neighborhood Hits	235	Shared Neighborhood Hits	23
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

NCF1_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.167375 (rank : 138)
Query Neighborhood Hits	409	Target Neighborhood Hits	198	Shared Neighborhood Hits	112
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

NCF4_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.180825 (rank : 125)
Query Neighborhood Hits	409	Target Neighborhood Hits	161	Shared Neighborhood Hits	97
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.189382 (rank : 117)
Query Neighborhood Hits	409	Target Neighborhood Hits	177	Shared Neighborhood Hits	105
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCOA6_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.053626 (rank : 397)
Query Neighborhood Hits	409	Target Neighborhood Hits	1076	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NEBL_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.114751 (rank : 180)
Query Neighborhood Hits	409	Target Neighborhood Hits	457	Shared Neighborhood Hits	114
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

NEBU_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.103826 (rank : 194)
Query Neighborhood Hits	409	Target Neighborhood Hits	420	Shared Neighborhood Hits	117
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NOXO1_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.126810 (rank : 169)
Query Neighborhood Hits	409	Target Neighborhood Hits	114	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NPHP1_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.122101 (rank : 175)
Query Neighborhood Hits	409	Target Neighborhood Hits	288	Shared Neighborhood Hits	97
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.139240 (rank : 157)
Query Neighborhood Hits	409	Target Neighborhood Hits	267	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

P55G_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.090123 (rank : 222)
Query Neighborhood Hits	409	Target Neighborhood Hits	451	Shared Neighborhood Hits	36
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.088308 (rank : 229)
Query Neighborhood Hits	409	Target Neighborhood Hits	401	Shared Neighborhood Hits	34
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PACN3_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.143716 (rank : 153)
Query Neighborhood Hits	409	Target Neighborhood Hits	385	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

PCLO_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.071747 (rank : 278)
Query Neighborhood Hits	409	Target Neighborhood Hits	2046	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCTL_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.056599 (rank : 373)
Query Neighborhood Hits	409	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.057254 (rank : 371)
Query Neighborhood Hits	409	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PDZD8_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.066279 (rank : 300)
Query Neighborhood Hits	409	Target Neighborhood Hits	185	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PELP1_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.055260 (rank : 383)
Query Neighborhood Hits	409	Target Neighborhood Hits	596	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PEX13_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.100215 (rank : 201)
Query Neighborhood Hits	409	Target Neighborhood Hits	128	Shared Neighborhood Hits	79
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.100869 (rank : 200)
Query Neighborhood Hits	409	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PKHG1_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.095401 (rank : 210)
Query Neighborhood Hits	409	Target Neighborhood Hits	174	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

PLCG1_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.121806 (rank : 176)
Query Neighborhood Hits	409	Target Neighborhood Hits	293	Shared Neighborhood Hits	112
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG1_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.126180 (rank : 172)
Query Neighborhood Hits	409	Target Neighborhood Hits	314	Shared Neighborhood Hits	118
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.121219 (rank : 177)
Query Neighborhood Hits	409	Target Neighborhood Hits	280	Shared Neighborhood Hits	109
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

PRB3_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.090621 (rank : 221)
Query Neighborhood Hits	409	Target Neighborhood Hits	318	Shared Neighborhood Hits	69
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.070020 (rank : 281)
Query Neighborhood Hits	409	Target Neighborhood Hits	330	Shared Neighborhood Hits	71
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PREX1_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.102822 (rank : 197)
Query Neighborhood Hits	409	Target Neighborhood Hits	177	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRG4_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.070972 (rank : 279)
Query Neighborhood Hits	409	Target Neighborhood Hits	764	Shared Neighborhood Hits	106
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.103099 (rank : 195)
Query Neighborhood Hits	409	Target Neighborhood Hits	385	Shared Neighborhood Hits	87
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRR12_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.095877 (rank : 209)
Query Neighborhood Hits	409	Target Neighborhood Hits	460	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.058268 (rank : 362)
Query Neighborhood Hits	409	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.072407 (rank : 276)
Query Neighborhood Hits	409	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRRT1_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.054098 (rank : 389)
Query Neighborhood Hits	409	Target Neighborhood Hits	94	Shared Neighborhood Hits	27
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PRRT1_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.053796 (rank : 392)
Query Neighborhood Hits	409	Target Neighborhood Hits	102	Shared Neighborhood Hits	29
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PRRT3_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.057680 (rank : 368)
Query Neighborhood Hits	409	Target Neighborhood Hits	998	Shared Neighborhood Hits	131
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PYGO2_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.053645 (rank : 396)
Query Neighborhood Hits	409	Target Neighborhood Hits	189	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RAPH1_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.080267 (rank : 249)
Query Neighborhood Hits	409	Target Neighborhood Hits	593	Shared Neighborhood Hits	107
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RASA1_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.060710 (rank : 344)
Query Neighborhood Hits	409	Target Neighborhood Hits	258	Shared Neighborhood Hits	40
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RERE_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.075424 (rank : 263)
Query Neighborhood Hits	409	Target Neighborhood Hits	779	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.065381 (rank : 306)
Query Neighborhood Hits	409	Target Neighborhood Hits	785	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RGNEF_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.069829 (rank : 283)
Query Neighborhood Hits	409	Target Neighborhood Hits	641	Shared Neighborhood Hits	54
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RIMB1_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.063358 (rank : 318)
Query Neighborhood Hits	409	Target Neighborhood Hits	1479	Shared Neighborhood Hits	163
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB2_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.091769 (rank : 215)
Query Neighborhood Hits	409	Target Neighborhood Hits	263	Shared Neighborhood Hits	93
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.093060 (rank : 213)
Query Neighborhood Hits	409	Target Neighborhood Hits	246	Shared Neighborhood Hits	87
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RSMN_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.056280 (rank : 377)
Query Neighborhood Hits	409	Target Neighborhood Hits	110	Shared Neighborhood Hits	31
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.056280 (rank : 378)
Query Neighborhood Hits	409	Target Neighborhood Hits	110	Shared Neighborhood Hits	31
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RUSC2_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.080428 (rank : 248)
Query Neighborhood Hits	409	Target Neighborhood Hits	205	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SASH1_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.052581 (rank : 405)
Query Neighborhood Hits	409	Target Neighborhood Hits	292	Shared Neighborhood Hits	91
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SC24C_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.051037 (rank : 424)
Query Neighborhood Hits	409	Target Neighborhood Hits	662	Shared Neighborhood Hits	83
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SC24D_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.053754 (rank : 393)
Query Neighborhood Hits	409	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SELPL_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.050195 (rank : 434)
Query Neighborhood Hits	409	Target Neighborhood Hits	588	Shared Neighborhood Hits	73
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SET1A_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.052667 (rank : 402)
Query Neighborhood Hits	409	Target Neighborhood Hits	690	Shared Neighborhood Hits	91
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF01_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.061678 (rank : 335)
Query Neighborhood Hits	409	Target Neighborhood Hits	287	Shared Neighborhood Hits	58
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.051735 (rank : 415)
Query Neighborhood Hits	409	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF3A2_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.099491 (rank : 202)
Query Neighborhood Hits	409	Target Neighborhood Hits	263	Shared Neighborhood Hits	58
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.098260 (rank : 205)
Query Neighborhood Hits	409	Target Neighborhood Hits	247	Shared Neighborhood Hits	54
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.054847 (rank : 385)
Query Neighborhood Hits	409	Target Neighborhood Hits	986	Shared Neighborhood Hits	116
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SH21A_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.050830 (rank : 427)
Query Neighborhood Hits	409	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

SH21A_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.050192 (rank : 435)
Query Neighborhood Hits	409	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

SHB_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.050546 (rank : 430)
Query Neighborhood Hits	409	Target Neighborhood Hits	137	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

SHD_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.053707 (rank : 394)
Query Neighborhood Hits	409	Target Neighborhood Hits	137	Shared Neighborhood Hits	29
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SHLB1_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.061553 (rank : 336)
Query Neighborhood Hits	409	Target Neighborhood Hits	96	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

SHLB1_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.062123 (rank : 330)
Query Neighborhood Hits	409	Target Neighborhood Hits	101	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

SHLB2_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.067822 (rank : 295)
Query Neighborhood Hits	409	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.067835 (rank : 294)
Query Neighborhood Hits	409	Target Neighborhood Hits	88	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SLAP2_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.053912 (rank : 390)
Query Neighborhood Hits	409	Target Neighborhood Hits	136	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

SMAP1_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.052164 (rank : 407)
Query Neighborhood Hits	409	Target Neighborhood Hits	98	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.051962 (rank : 412)
Query Neighborhood Hits	409	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.051979 (rank : 411)
Query Neighborhood Hits	409	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.051804 (rank : 414)
Query Neighborhood Hits	409	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMR1_MOUSE
θ value	θ > 10 (rank : 577)	NC score	0.052886 (rank : 401)
Query Neighborhood Hits	409	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SMR3A_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.109390 (rank : 186)
Query Neighborhood Hits	409	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SNX18_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.090092 (rank : 224)
Query Neighborhood Hits	409	Target Neighborhood Hits	207	Shared Neighborhood Hits	95
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.088829 (rank : 225)
Query Neighborhood Hits	409	Target Neighborhood Hits	198	Shared Neighborhood Hits	93
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX9_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.057992 (rank : 365)
Query Neighborhood Hits	409	Target Neighborhood Hits	148	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

SON_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.053497 (rank : 398)
Query Neighborhood Hits	409	Target Neighborhood Hits	957	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SOS1_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.051195 (rank : 423)
Query Neighborhood Hits	409	Target Neighborhood Hits	274	Shared Neighborhood Hits	50
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SPN90_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.081499 (rank : 244)
Query Neighborhood Hits	409	Target Neighborhood Hits	157	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPN90_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.068890 (rank : 289)
Query Neighborhood Hits	409	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SPTA1_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.069463 (rank : 287)
Query Neighborhood Hits	409	Target Neighborhood Hits	748	Shared Neighborhood Hits	118
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.073190 (rank : 269)
Query Neighborhood Hits	409	Target Neighborhood Hits	675	Shared Neighborhood Hits	115
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA2_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.081360 (rank : 245)
Query Neighborhood Hits	409	Target Neighborhood Hits	888	Shared Neighborhood Hits	125
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SRRM1_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.078577 (rank : 254)
Query Neighborhood Hits	409	Target Neighborhood Hits	690	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.083696 (rank : 238)
Query Neighborhood Hits	409	Target Neighborhood Hits	966	Shared Neighborhood Hits	115
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.066429 (rank : 299)
Query Neighborhood Hits	409	Target Neighborhood Hits	1296	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.059733 (rank : 351)
Query Neighborhood Hits	409	Target Neighborhood Hits	1470	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STS2_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.056935 (rank : 372)
Query Neighborhood Hits	409	Target Neighborhood Hits	108	Shared Neighborhood Hits	66
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

SYN1_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.060059 (rank : 349)
Query Neighborhood Hits	409	Target Neighborhood Hits	419	Shared Neighborhood Hits	92
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.055682 (rank : 381)
Query Neighborhood Hits	409	Target Neighborhood Hits	363	Shared Neighborhood Hits	72
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ1_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.066623 (rank : 298)
Query Neighborhood Hits	409	Target Neighborhood Hits	498	Shared Neighborhood Hits	92
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.066237 (rank : 301)
Query Neighborhood Hits	409	Target Neighborhood Hits	516	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

T22D2_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.061779 (rank : 334)
Query Neighborhood Hits	409	Target Neighborhood Hits	250	Shared Neighborhood Hits	48
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TAB3_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.052071 (rank : 410)
Query Neighborhood Hits	409	Target Neighborhood Hits	273	Shared Neighborhood Hits	41
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TAF4_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.111890 (rank : 183)
Query Neighborhood Hits	409	Target Neighborhood Hits	687	Shared Neighborhood Hits	100
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TCRG1_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.064949 (rank : 309)
Query Neighborhood Hits	409	Target Neighborhood Hits	929	Shared Neighborhood Hits	67
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TIAM1_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.097776 (rank : 207)
Query Neighborhood Hits	409	Target Neighborhood Hits	205	Shared Neighborhood Hits	37
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

UN13A_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.064839 (rank : 310)
Query Neighborhood Hits	409	Target Neighborhood Hits	285	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.062679 (rank : 325)
Query Neighborhood Hits	409	Target Neighborhood Hits	217	Shared Neighborhood Hits	29
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.059352 (rank : 354)
Query Neighborhood Hits	409	Target Neighborhood Hits	210	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

WASF2_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.058004 (rank : 364)
Query Neighborhood Hits	409	Target Neighborhood Hits	280	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASF2_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.061072 (rank : 339)
Query Neighborhood Hits	409	Target Neighborhood Hits	315	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASF4_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.052637 (rank : 404)
Query Neighborhood Hits	409	Target Neighborhood Hits	282	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASIP_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.098230 (rank : 206)
Query Neighborhood Hits	409	Target Neighborhood Hits	458	Shared Neighborhood Hits	101
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.099106 (rank : 203)
Query Neighborhood Hits	409	Target Neighborhood Hits	392	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.058542 (rank : 361)
Query Neighborhood Hits	409	Target Neighborhood Hits	312	Shared Neighborhood Hits	66
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASL_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.065608 (rank : 305)
Query Neighborhood Hits	409	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WBP11_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.083336 (rank : 239)
Query Neighborhood Hits	409	Target Neighborhood Hits	354	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.081934 (rank : 242)
Query Neighborhood Hits	409	Target Neighborhood Hits	362	Shared Neighborhood Hits	69
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WBS14_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.055856 (rank : 379)
Query Neighborhood Hits	409	Target Neighborhood Hits	273	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

WIRE_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.087381 (rank : 232)
Query Neighborhood Hits	409	Target Neighborhood Hits	329	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.084211 (rank : 234)
Query Neighborhood Hits	409	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.077088 (rank : 259)
Query Neighborhood Hits	409	Target Neighborhood Hits	505	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZN207_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.079589 (rank : 253)
Query Neighborhood Hits	409	Target Neighborhood Hits	326	Shared Neighborhood Hits	48
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

TCGAP_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	409	Target Neighborhood Hits	409	Shared Neighborhood Hits	409
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_HUMAN
NC score	0.875877 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	409	Target Neighborhood Hits	872	Shared Neighborhood Hits	319
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG09_HUMAN
NC score	0.812694 (rank : 3)	θ value	1.24688e-25 (rank : 9)
Query Neighborhood Hits	409	Target Neighborhood Hits	186	Shared Neighborhood Hits	89
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

3BP1_MOUSE
NC score	0.782222 (rank : 4)	θ value	5.42112e-21 (rank : 12)
Query Neighborhood Hits	409	Target Neighborhood Hits	238	Shared Neighborhood Hits	103
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_HUMAN
NC score	0.781580 (rank : 5)	θ value	1.42661e-21 (rank : 11)
Query Neighborhood Hits	409	Target Neighborhood Hits	376	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG12_HUMAN
NC score	0.780060 (rank : 6)	θ value	5.06226e-27 (rank : 8)
Query Neighborhood Hits	409	Target Neighborhood Hits	190	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.780012 (rank : 7)	θ value	7.80994e-28 (rank : 7)
Query Neighborhood Hits	409	Target Neighborhood Hits	204	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

GMIP_MOUSE
NC score	0.767334 (rank : 8)	θ value	2.69047e-20 (rank : 16)
Query Neighborhood Hits	409	Target Neighborhood Hits	202	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.762887 (rank : 9)	θ value	8.65492e-19 (rank : 18)
Query Neighborhood Hits	409	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHIO_MOUSE
NC score	0.762454 (rank : 10)	θ value	2.86786e-30 (rank : 5)
Query Neighborhood Hits	409	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG04_HUMAN
NC score	0.755914 (rank : 11)	θ value	9.24701e-21 (rank : 14)
Query Neighborhood Hits	409	Target Neighborhood Hits	307	Shared Neighborhood Hits	168
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RGAP1_HUMAN
NC score	0.755000 (rank : 12)	θ value	6.20254e-17 (rank : 25)
Query Neighborhood Hits	409	Target Neighborhood Hits	189	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
NC score	0.754107 (rank : 13)	θ value	2.35696e-16 (rank : 28)
Query Neighborhood Hits	409	Target Neighborhood Hits	185	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG26_HUMAN
NC score	0.752847 (rank : 14)	θ value	1.5773e-20 (rank : 15)
Query Neighborhood Hits	409	Target Neighborhood Hits	281	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

CHIN_MOUSE
NC score	0.745813 (rank : 15)	θ value	4.42448e-31 (rank : 4)
Query Neighborhood Hits	409	Target Neighborhood Hits	229	Shared Neighborhood Hits	86
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
NC score	0.745046 (rank : 16)	θ value	1.52067e-31 (rank : 3)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	83
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
NC score	0.743399 (rank : 17)	θ value	1.08979e-29 (rank : 6)
Query Neighborhood Hits	409	Target Neighborhood Hits	220	Shared Neighborhood Hits	82
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG06_HUMAN
NC score	0.741170 (rank : 18)	θ value	4.44505e-15 (rank : 31)
Query Neighborhood Hits	409	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.737563 (rank : 19)	θ value	4.91457e-14 (rank : 39)
Query Neighborhood Hits	409	Target Neighborhood Hits	105	Shared Neighborhood Hits	64
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

GRLF1_HUMAN
NC score	0.731303 (rank : 20)	θ value	1.80466e-16 (rank : 27)
Query Neighborhood Hits	409	Target Neighborhood Hits	167	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

ABR_HUMAN
NC score	0.727479 (rank : 21)	θ value	8.93572e-24 (rank : 10)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	92
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

OPHN1_HUMAN
NC score	0.725903 (rank : 22)	θ value	1.47631e-18 (rank : 19)
Query Neighborhood Hits	409	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
NC score	0.724562 (rank : 23)	θ value	5.07402e-19 (rank : 17)
Query Neighborhood Hits	409	Target Neighborhood Hits	174	Shared Neighborhood Hits	66
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

BCR_HUMAN
NC score	0.718903 (rank : 24)	θ value	5.42112e-21 (rank : 13)
Query Neighborhood Hits	409	Target Neighborhood Hits	204	Shared Neighborhood Hits	99
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG01_HUMAN
NC score	0.718727 (rank : 25)	θ value	1.68911e-14 (rank : 35)
Query Neighborhood Hits	409	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

SRGP2_HUMAN
NC score	0.710737 (rank : 26)	θ value	1.86753e-13 (rank : 40)
Query Neighborhood Hits	409	Target Neighborhood Hits	331	Shared Neighborhood Hits	160
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG18_HUMAN
NC score	0.710218 (rank : 27)	θ value	1.133e-10 (rank : 47)
Query Neighborhood Hits	409	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

SRGP2_MOUSE
NC score	0.704246 (rank : 28)	θ value	9.26847e-13 (rank : 43)
Query Neighborhood Hits	409	Target Neighborhood Hits	324	Shared Neighborhood Hits	163
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG18_MOUSE
NC score	0.703954 (rank : 29)	θ value	2.52405e-10 (rank : 50)
Query Neighborhood Hits	409	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_HUMAN
NC score	0.703342 (rank : 30)	θ value	2.88119e-14 (rank : 36)
Query Neighborhood Hits	409	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_MOUSE
NC score	0.703292 (rank : 31)	θ value	4.59992e-12 (rank : 46)
Query Neighborhood Hits	409	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG05_MOUSE
NC score	0.700418 (rank : 32)	θ value	8.95645e-16 (rank : 30)
Query Neighborhood Hits	409	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SRGP1_HUMAN
NC score	0.698897 (rank : 33)	θ value	4.02038e-16 (rank : 29)
Query Neighborhood Hits	409	Target Neighborhood Hits	390	Shared Neighborhood Hits	156
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
NC score	0.693161 (rank : 34)	θ value	1.29331e-14 (rank : 33)
Query Neighborhood Hits	409	Target Neighborhood Hits	432	Shared Neighborhood Hits	158
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG05_HUMAN
NC score	0.689424 (rank : 35)	θ value	4.91457e-14 (rank : 38)
Query Neighborhood Hits	409	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG25_MOUSE
NC score	0.682238 (rank : 36)	θ value	1.058e-16 (rank : 26)
Query Neighborhood Hits	409	Target Neighborhood Hits	492	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RBP1_MOUSE
NC score	0.681662 (rank : 37)	θ value	1.92812e-18 (rank : 21)
Query Neighborhood Hits	409	Target Neighborhood Hits	493	Shared Neighborhood Hits	73
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_HUMAN
NC score	0.663482 (rank : 38)	θ value	1.63225e-17 (rank : 23)
Query Neighborhood Hits	409	Target Neighborhood Hits	521	Shared Neighborhood Hits	77
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG25_HUMAN
NC score	0.655402 (rank : 39)	θ value	1.29331e-14 (rank : 34)
Query Neighborhood Hits	409	Target Neighborhood Hits	550	Shared Neighborhood Hits	77
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG07_MOUSE
NC score	0.637785 (rank : 40)	θ value	4.16044e-13 (rank : 41)
Query Neighborhood Hits	409	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.631254 (rank : 41)	θ value	3.52202e-12 (rank : 45)
Query Neighborhood Hits	409	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TAGAP_HUMAN
NC score	0.628284 (rank : 42)	θ value	1.17247e-07 (rank : 59)
Query Neighborhood Hits	409	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
NC score	0.627499 (rank : 43)	θ value	4.92598e-06 (rank : 64)
Query Neighborhood Hits	409	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CE005_HUMAN
NC score	0.600763 (rank : 44)	θ value	5.43371e-13 (rank : 42)
Query Neighborhood Hits	409	Target Neighborhood Hits	213	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

STAR8_MOUSE
NC score	0.598285 (rank : 45)	θ value	1.9326e-10 (rank : 49)
Query Neighborhood Hits	409	Target Neighborhood Hits	101	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CE005_MOUSE
NC score	0.596279 (rank : 46)	θ value	1.58096e-12 (rank : 44)
Query Neighborhood Hits	409	Target Neighborhood Hits	238	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

STAR8_HUMAN
NC score	0.594655 (rank : 47)	θ value	4.30538e-10 (rank : 51)
Query Neighborhood Hits	409	Target Neighborhood Hits	216	Shared Neighborhood Hits	78
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND2_HUMAN
NC score	0.591166 (rank : 48)	θ value	3.76295e-14 (rank : 37)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

STA13_HUMAN
NC score	0.591115 (rank : 49)	θ value	1.133e-10 (rank : 48)
Query Neighborhood Hits	409	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
NC score	0.581081 (rank : 50)	θ value	5.62301e-10 (rank : 52)
Query Neighborhood Hits	409	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND3_MOUSE
NC score	0.567930 (rank : 51)	θ value	7.58209e-15 (rank : 32)
Query Neighborhood Hits	409	Target Neighborhood Hits	228	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.565304 (rank : 52)	θ value	2.7842e-17 (rank : 24)
Query Neighborhood Hits	409	Target Neighborhood Hits	275	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

K1688_MOUSE
NC score	0.543275 (rank : 53)	θ value	6.21693e-09 (rank : 55)
Query Neighborhood Hits	409	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.530734 (rank : 54)	θ value	1.06045e-08 (rank : 57)
Query Neighborhood Hits	409	Target Neighborhood Hits	217	Shared Neighborhood Hits	82
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND1_MOUSE
NC score	0.501698 (rank : 55)	θ value	1.63604e-09 (rank : 53)
Query Neighborhood Hits	409	Target Neighborhood Hits	260	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.482253 (rank : 56)	θ value	2.79066e-09 (rank : 54)
Query Neighborhood Hits	409	Target Neighborhood Hits	284	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

P85A_HUMAN
NC score	0.420728 (rank : 57)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	409	Target Neighborhood Hits	479	Shared Neighborhood Hits	115
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.415902 (rank : 58)	θ value	1.38499e-08 (rank : 58)
Query Neighborhood Hits	409	Target Neighborhood Hits	435	Shared Neighborhood Hits	119
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

MYO9B_MOUSE
NC score	0.407391 (rank : 59)	θ value	5.60996e-18 (rank : 22)
Query Neighborhood Hits	409	Target Neighborhood Hits	311	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.406604 (rank : 60)	θ value	1.92812e-18 (rank : 20)
Query Neighborhood Hits	409	Target Neighborhood Hits	641	Shared Neighborhood Hits	114
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

I5P2_HUMAN
NC score	0.339603 (rank : 61)	θ value	9.29e-05 (rank : 68)
Query Neighborhood Hits	409	Target Neighborhood Hits	86	Shared Neighborhood Hits	55
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.331420 (rank : 62)	θ value	9.29e-05 (rank : 69)
Query Neighborhood Hits	409	Target Neighborhood Hits	77	Shared Neighborhood Hits	55
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

CD2AP_HUMAN
NC score	0.267432 (rank : 63)	θ value	0.00228821 (rank : 82)
Query Neighborhood Hits	409	Target Neighborhood Hits	315	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

SH3K1_MOUSE
NC score	0.266947 (rank : 64)	θ value	0.0193708 (rank : 114)
Query Neighborhood Hits	409	Target Neighborhood Hits	332	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

CD2AP_MOUSE
NC score	0.264411 (rank : 65)	θ value	0.00134147 (rank : 76)
Query Neighborhood Hits	409	Target Neighborhood Hits	336	Shared Neighborhood Hits	140
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

SH3K1_HUMAN
NC score	0.263559 (rank : 66)	θ value	0.0193708 (rank : 113)
Query Neighborhood Hits	409	Target Neighborhood Hits	341	Shared Neighborhood Hits	133
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

HCLS1_HUMAN
NC score	0.262393 (rank : 67)	θ value	0.00175202 (rank : 79)
Query Neighborhood Hits	409	Target Neighborhood Hits	358	Shared Neighborhood Hits	136
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
NC score	0.258436 (rank : 68)	θ value	0.00298849 (rank : 86)
Query Neighborhood Hits	409	Target Neighborhood Hits	329	Shared Neighborhood Hits	132
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

STAC3_MOUSE
NC score	0.254533 (rank : 69)	θ value	0.00102713 (rank : 75)
Query Neighborhood Hits	409	Target Neighborhood Hits	232	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_HUMAN
NC score	0.252046 (rank : 70)	θ value	0.00102713 (rank : 74)
Query Neighborhood Hits	409	Target Neighborhood Hits	228	Shared Neighborhood Hits	109
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

GRAP_HUMAN
NC score	0.246921 (rank : 71)	θ value	5.81887e-07 (rank : 60)
Query Neighborhood Hits	409	Target Neighborhood Hits	307	Shared Neighborhood Hits	136
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
NC score	0.243978 (rank : 72)	θ value	2.21117e-06 (rank : 62)
Query Neighborhood Hits	409	Target Neighborhood Hits	309	Shared Neighborhood Hits	135
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

STAC_MOUSE
NC score	0.242710 (rank : 73)	θ value	0.0431538 (rank : 128)
Query Neighborhood Hits	409	Target Neighborhood Hits	268	Shared Neighborhood Hits	121
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SRC8_MOUSE
NC score	0.241988 (rank : 74)	θ value	0.00102713 (rank : 73)
Query Neighborhood Hits	409	Target Neighborhood Hits	292	Shared Neighborhood Hits	118
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

STAC_HUMAN
NC score	0.240160 (rank : 75)	θ value	0.0563607 (rank : 133)
Query Neighborhood Hits	409	Target Neighborhood Hits	276	Shared Neighborhood Hits	120
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VINEX_MOUSE
NC score	0.237863 (rank : 76)	θ value	0.0563607 (rank : 135)
Query Neighborhood Hits	409	Target Neighborhood Hits	286	Shared Neighborhood Hits	133
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

SRC8_HUMAN
NC score	0.237176 (rank : 77)	θ value	0.00509761 (rank : 95)
Query Neighborhood Hits	409	Target Neighborhood Hits	269	Shared Neighborhood Hits	116
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

NCF2_HUMAN
NC score	0.236214 (rank : 78)	θ value	0.813845 (rank : 199)
Query Neighborhood Hits	409	Target Neighborhood Hits	229	Shared Neighborhood Hits	121
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCK2_HUMAN
NC score	0.235367 (rank : 79)	θ value	0.0113563 (rank : 105)
Query Neighborhood Hits	409	Target Neighborhood Hits	310	Shared Neighborhood Hits	129
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

VINEX_HUMAN
NC score	0.232886 (rank : 80)	θ value	0.125558 (rank : 150)
Query Neighborhood Hits	409	Target Neighborhood Hits	270	Shared Neighborhood Hits	136
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

GRB2_HUMAN
NC score	0.229294 (rank : 81)	θ value	0.163984 (rank : 155)
Query Neighborhood Hits	409	Target Neighborhood Hits	310	Shared Neighborhood Hits	131
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.229153 (rank : 82)	θ value	0.163984 (rank : 156)
Query Neighborhood Hits	409	Target Neighborhood Hits	312	Shared Neighborhood Hits	131
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRAP2_HUMAN
NC score	0.226185 (rank : 83)	θ value	0.0330416 (rank : 121)
Query Neighborhood Hits	409	Target Neighborhood Hits	304	Shared Neighborhood Hits	132
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

ABI2_HUMAN
NC score	0.225308 (rank : 84)	θ value	0.47712 (rank : 176)
Query Neighborhood Hits	409	Target Neighborhood Hits	350	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

GRAP2_MOUSE
NC score	0.225047 (rank : 85)	θ value	0.0431538 (rank : 126)
Query Neighborhood Hits	409	Target Neighborhood Hits	297	Shared Neighborhood Hits	131
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

DNMBP_HUMAN
NC score	0.223160 (rank : 86)	θ value	0.0193708 (rank : 111)
Query Neighborhood Hits	409	Target Neighborhood Hits	413	Shared Neighborhood Hits	141
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SRBS1_HUMAN
NC score	0.222496 (rank : 87)	θ value	1.38821 (rank : 236)
Query Neighborhood Hits	409	Target Neighborhood Hits	396	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
NC score	0.222305 (rank : 88)	θ value	2.36792 (rank : 274)
Query Neighborhood Hits	409	Target Neighborhood Hits	409	Shared Neighborhood Hits	143
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ARHG7_MOUSE
NC score	0.221622 (rank : 89)	θ value	0.0563607 (rank : 130)
Query Neighborhood Hits	409	Target Neighborhood Hits	396	Shared Neighborhood Hits	130
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

NCK1_HUMAN
NC score	0.220855 (rank : 90)	θ value	0.0148317 (rank : 108)
Query Neighborhood Hits	409	Target Neighborhood Hits	312	Shared Neighborhood Hits	128
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

DNMBP_MOUSE
NC score	0.217378 (rank : 91)	θ value	0.0736092 (rank : 136)
Query Neighborhood Hits	409	Target Neighborhood Hits	435	Shared Neighborhood Hits	149
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

STAM1_HUMAN
NC score	0.217316 (rank : 92)	θ value	0.0113563 (rank : 107)
Query Neighborhood Hits	409	Target Neighborhood Hits	271	Shared Neighborhood Hits	125
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ABI2_MOUSE
NC score	0.216974 (rank : 93)	θ value	0.47712 (rank : 177)
Query Neighborhood Hits	409	Target Neighborhood Hits	266	Shared Neighborhood Hits	132
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

STAM1_MOUSE
NC score	0.216727 (rank : 94)	θ value	0.00869519 (rank : 102)
Query Neighborhood Hits	409	Target Neighborhood Hits	273	Shared Neighborhood Hits	127
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

ARHG7_HUMAN
NC score	0.213841 (rank : 95)	θ value	0.0961366 (rank : 140)
Query Neighborhood Hits	409	Target Neighborhood Hits	347	Shared Neighborhood Hits	128
SwissProt Accessions	Q14155, Q6P9G3, Q6PII2, Q86W63, Q8N3M1	Gene names	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COOL-1) (p85).

STAM2_MOUSE
NC score	0.213557 (rank : 96)	θ value	0.00390308 (rank : 92)
Query Neighborhood Hits	409	Target Neighborhood Hits	285	Shared Neighborhood Hits	125
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STAM2_HUMAN
NC score	0.212041 (rank : 97)	θ value	0.00298849 (rank : 88)
Query Neighborhood Hits	409	Target Neighborhood Hits	288	Shared Neighborhood Hits	125
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

ARHG4_HUMAN
NC score	0.209376 (rank : 98)	θ value	4.1701e-05 (rank : 66)
Query Neighborhood Hits	409	Target Neighborhood Hits	242	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ABI1_MOUSE
NC score	0.208059 (rank : 99)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	409	Target Neighborhood Hits	246	Shared Neighborhood Hits	135
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ARHG6_MOUSE
NC score	0.207913 (rank : 100)	θ value	0.00665767 (rank : 96)
Query Neighborhood Hits	409	Target Neighborhood Hits	394	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

ARHG9_MOUSE
NC score	0.206944 (rank : 101)	θ value	0.00390308 (rank : 90)
Query Neighborhood Hits	409	Target Neighborhood Hits	234	Shared Neighborhood Hits	121
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG9_HUMAN
NC score	0.206764 (rank : 102)	θ value	0.00390308 (rank : 89)
Query Neighborhood Hits	409	Target Neighborhood Hits	235	Shared Neighborhood Hits	123
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

PPIP1_HUMAN
NC score	0.206236 (rank : 103)	θ value	0.00869519 (rank : 100)
Query Neighborhood Hits	409	Target Neighborhood Hits	389	Shared Neighborhood Hits	122
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

VAV2_MOUSE
NC score	0.206003 (rank : 104)	θ value	0.0252991 (rank : 118)
Query Neighborhood Hits	409	Target Neighborhood Hits	456	Shared Neighborhood Hits	141
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV_MOUSE
NC score	0.204857 (rank : 105)	θ value	0.0563607 (rank : 134)
Query Neighborhood Hits	409	Target Neighborhood Hits	430	Shared Neighborhood Hits	136
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VAV2_HUMAN
NC score	0.204252 (rank : 106)	θ value	0.0330416 (rank : 122)
Query Neighborhood Hits	409	Target Neighborhood Hits	453	Shared Neighborhood Hits	134
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

BCAR1_MOUSE
NC score	0.200804 (rank : 107)	θ value	0.00175202 (rank : 78)
Query Neighborhood Hits	409	Target Neighborhood Hits	438	Shared Neighborhood Hits	151
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

VAV_HUMAN
NC score	0.200714 (rank : 108)	θ value	0.0736092 (rank : 138)
Query Neighborhood Hits	409	Target Neighborhood Hits	452	Shared Neighborhood Hits	134
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ARHG6_HUMAN
NC score	0.200115 (rank : 109)	θ value	0.125558 (rank : 145)
Query Neighborhood Hits	409	Target Neighborhood Hits	376	Shared Neighborhood Hits	124
SwissProt Accessions	Q15052, Q15396, Q5JQ66, Q86XH0	Gene names	ARHGEF6, COOL2, KIAA0006, PIXA
Domain Architecture
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).

VAV3_HUMAN
NC score	0.198615 (rank : 110)	θ value	0.365318 (rank : 175)
Query Neighborhood Hits	409	Target Neighborhood Hits	398	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

ABI1_HUMAN
NC score	0.198395 (rank : 111)	θ value	2.36792 (rank : 258)
Query Neighborhood Hits	409	Target Neighborhood Hits	257	Shared Neighborhood Hits	136
SwissProt Accessions	Q8IZP0, O15147, O76049, O95060, Q5W070, Q5W072, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8	Gene names	ABI1, SSH3BP1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Nap1-binding protein) (Nap1BP) (Abl-binding protein 4) (AblBP4).

PPIP1_MOUSE
NC score	0.197230 (rank : 112)	θ value	0.0563607 (rank : 131)
Query Neighborhood Hits	409	Target Neighborhood Hits	377	Shared Neighborhood Hits	122
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

VAV3_MOUSE
NC score	0.197009 (rank : 113)	θ value	0.62314 (rank : 190)
Query Neighborhood Hits	409	Target Neighborhood Hits	404	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ITSN1_MOUSE
NC score	0.195264 (rank : 114)	θ value	5.81887e-07 (rank : 61)
Query Neighborhood Hits	409	Target Neighborhood Hits	1669	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.194439 (rank : 115)	θ value	2.21117e-06 (rank : 63)
Query Neighborhood Hits	409	Target Neighborhood Hits	1757	Shared Neighborhood Hits	186
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_HUMAN
NC score	0.193277 (rank : 116)	θ value	0.00134147 (rank : 77)
Query Neighborhood Hits	409	Target Neighborhood Hits	1173	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

NCF4_MOUSE
NC score	0.189382 (rank : 117)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	409	Target Neighborhood Hits	177	Shared Neighborhood Hits	105
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SH3G2_MOUSE
NC score	0.189029 (rank : 118)	θ value	0.47712 (rank : 182)
Query Neighborhood Hits	409	Target Neighborhood Hits	319	Shared Neighborhood Hits	124
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

BCAR1_HUMAN
NC score	0.188088 (rank : 119)	θ value	0.00869519 (rank : 98)
Query Neighborhood Hits	409	Target Neighborhood Hits	554	Shared Neighborhood Hits	162
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CRKL_HUMAN
NC score	0.186521 (rank : 120)	θ value	0.47712 (rank : 179)
Query Neighborhood Hits	409	Target Neighborhood Hits	313	Shared Neighborhood Hits	129
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

CT032_HUMAN
NC score	0.184512 (rank : 121)	θ value	0.125558 (rank : 146)
Query Neighborhood Hits	409	Target Neighborhood Hits	235	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

ITSN2_MOUSE
NC score	0.184253 (rank : 122)	θ value	0.00175202 (rank : 80)
Query Neighborhood Hits	409	Target Neighborhood Hits	1371	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

SH3G2_HUMAN
NC score	0.184191 (rank : 123)	θ value	2.36792 (rank : 272)
Query Neighborhood Hits	409	Target Neighborhood Hits	324	Shared Neighborhood Hits	122
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

OSTF1_HUMAN
NC score	0.181448 (rank : 124)	θ value	0.00228821 (rank : 84)
Query Neighborhood Hits	409	Target Neighborhood Hits	466	Shared Neighborhood Hits	126
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

NCF4_HUMAN
NC score	0.180825 (rank : 125)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	409	Target Neighborhood Hits	161	Shared Neighborhood Hits	97
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF1_MOUSE
NC score	0.178988 (rank : 126)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	409	Target Neighborhood Hits	198	Shared Neighborhood Hits	108
SwissProt Accessions	Q09014, O70144, Q9JI34	Gene names	Ncf1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K).

OSTF1_MOUSE
NC score	0.178976 (rank : 127)	θ value	0.00175202 (rank : 81)
Query Neighborhood Hits	409	Target Neighborhood Hits	467	Shared Neighborhood Hits	125
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

SH3G1_HUMAN
NC score	0.178778 (rank : 128)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	409	Target Neighborhood Hits	307	Shared Neighborhood Hits	118
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G3_MOUSE
NC score	0.177574 (rank : 129)	θ value	1.81305 (rank : 254)
Query Neighborhood Hits	409	Target Neighborhood Hits	236	Shared Neighborhood Hits	113
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

CRKL_MOUSE
NC score	0.177532 (rank : 130)	θ value	0.813845 (rank : 193)
Query Neighborhood Hits	409	Target Neighborhood Hits	307	Shared Neighborhood Hits	124
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

SH3G3_HUMAN
NC score	0.176605 (rank : 131)	θ value	2.36792 (rank : 273)
Query Neighborhood Hits	409	Target Neighborhood Hits	222	Shared Neighborhood Hits	113
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

SH3G1_MOUSE
NC score	0.175919 (rank : 132)	θ value	4.03905 (rank : 317)
Query Neighborhood Hits	409	Target Neighborhood Hits	291	Shared Neighborhood Hits	116
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

ARHG4_MOUSE
NC score	0.175005 (rank : 133)	θ value	0.0431538 (rank : 124)
Query Neighborhood Hits	409	Target Neighborhood Hits	185	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ABI3_MOUSE
NC score	0.173321 (rank : 134)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

PACN2_HUMAN
NC score	0.170228 (rank : 135)	θ value	0.813845 (rank : 201)
Query Neighborhood Hits	409	Target Neighborhood Hits	339	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

ABI3_HUMAN
NC score	0.167869 (rank : 136)	θ value	8.99809 (rank : 382)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	117
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

IASPP_HUMAN
NC score	0.167862 (rank : 137)	θ value	0.00869519 (rank : 99)
Query Neighborhood Hits	409	Target Neighborhood Hits	688	Shared Neighborhood Hits	165
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NCF1_HUMAN
NC score	0.167375 (rank : 138)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	409	Target Neighborhood Hits	198	Shared Neighborhood Hits	112
SwissProt Accessions	P14598, O43842, Q2PP07, Q9BU90, Q9BXI7, Q9BXI8, Q9UDV9, Q9UMU2	Gene names	NCF1
Domain Architecture
Description	Neutrophil cytosol factor 1 (NCF-1) (Neutrophil NADPH oxidase factor 1) (47 kDa neutrophil oxidase factor) (p47-phox) (NCF-47K) (47 kDa autosomal chronic granulomatous disease protein) (NOXO2).

PACN2_MOUSE
NC score	0.166509 (rank : 139)	θ value	0.813845 (rank : 202)
Query Neighborhood Hits	409	Target Neighborhood Hits	382	Shared Neighborhood Hits	123
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN1_MOUSE
NC score	0.164589 (rank : 140)	θ value	1.81305 (rank : 249)
Query Neighborhood Hits	409	Target Neighborhood Hits	283	Shared Neighborhood Hits	118
SwissProt Accessions	Q61644	Gene names	Pacsin1, Pacsin
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

PACN1_HUMAN
NC score	0.163100 (rank : 141)	θ value	1.81305 (rank : 248)
Query Neighborhood Hits	409	Target Neighborhood Hits	320	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BY11, Q9P2G8	Gene names	PACSIN1, KIAA1379
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 1.

EFS_HUMAN
NC score	0.162475 (rank : 142)	θ value	6.88961 (rank : 361)
Query Neighborhood Hits	409	Target Neighborhood Hits	348	Shared Neighborhood Hits	141
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

IASPP_MOUSE
NC score	0.160905 (rank : 143)	θ value	0.0252991 (rank : 115)
Query Neighborhood Hits	409	Target Neighborhood Hits	1024	Shared Neighborhood Hits	200
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

P85B_HUMAN
NC score	0.159808 (rank : 144)	θ value	0.279714 (rank : 163)
Query Neighborhood Hits	409	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

EFS_MOUSE
NC score	0.157451 (rank : 145)	θ value	8.99809 (rank : 394)
Query Neighborhood Hits	409	Target Neighborhood Hits	389	Shared Neighborhood Hits	149
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

CRK_MOUSE
NC score	0.157359 (rank : 146)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	409	Target Neighborhood Hits	314	Shared Neighborhood Hits	120
SwissProt Accessions	Q64010	Gene names	Crk, Crko
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

PACN3_MOUSE
NC score	0.156872 (rank : 147)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	409	Target Neighborhood Hits	380	Shared Neighborhood Hits	117
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

CRK_HUMAN
NC score	0.154672 (rank : 148)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	409	Target Neighborhood Hits	308	Shared Neighborhood Hits	121
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

AHI1_HUMAN
NC score	0.154052 (rank : 149)	θ value	0.0563607 (rank : 129)
Query Neighborhood Hits	409	Target Neighborhood Hits	537	Shared Neighborhood Hits	129
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AHI1_MOUSE
NC score	0.151346 (rank : 150)	θ value	0.365318 (rank : 165)
Query Neighborhood Hits	409	Target Neighborhood Hits	496	Shared Neighborhood Hits	131
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

ASPP1_HUMAN
NC score	0.149847 (rank : 151)	θ value	0.00298849 (rank : 85)
Query Neighborhood Hits	409	Target Neighborhood Hits	956	Shared Neighborhood Hits	150
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
NC score	0.145622 (rank : 152)	θ value	0.00509761 (rank : 93)
Query Neighborhood Hits	409	Target Neighborhood Hits	1244	Shared Neighborhood Hits	178
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PACN3_HUMAN
NC score	0.143716 (rank : 153)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	409	Target Neighborhood Hits	385	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

CASL_HUMAN
NC score	0.142848 (rank : 154)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	409	Target Neighborhood Hits	259	Shared Neighborhood Hits	118
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

DBNL_HUMAN
NC score	0.142151 (rank : 155)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	409	Target Neighborhood Hits	244	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DDEF2_MOUSE
NC score	0.139884 (rank : 156)	θ value	4.03905 (rank : 309)
Query Neighborhood Hits	409	Target Neighborhood Hits	625	Shared Neighborhood Hits	154
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

NPHP1_MOUSE
NC score	0.139240 (rank : 157)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	409	Target Neighborhood Hits	267	Shared Neighborhood Hits	107
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

DBNL_MOUSE
NC score	0.137571 (rank : 158)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	409	Target Neighborhood Hits	306	Shared Neighborhood Hits	106
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

PRP2_MOUSE
NC score	0.135829 (rank : 159)	θ value	0.365318 (rank : 170)
Query Neighborhood Hits	409	Target Neighborhood Hits	347	Shared Neighborhood Hits	82
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

CASL_MOUSE
NC score	0.135811 (rank : 160)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	409	Target Neighborhood Hits	225	Shared Neighborhood Hits	113
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

DDEF2_HUMAN
NC score	0.134639 (rank : 161)	θ value	4.03905 (rank : 308)
Query Neighborhood Hits	409	Target Neighborhood Hits	599	Shared Neighborhood Hits	143
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

MYO1F_HUMAN
NC score	0.132028 (rank : 162)	θ value	0.00509761 (rank : 94)
Query Neighborhood Hits	409	Target Neighborhood Hits	275	Shared Neighborhood Hits	127
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
NC score	0.130583 (rank : 163)	θ value	0.0113563 (rank : 104)
Query Neighborhood Hits	409	Target Neighborhood Hits	262	Shared Neighborhood Hits	120
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

DDEF1_MOUSE
NC score	0.129052 (rank : 164)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	409	Target Neighborhood Hits	592	Shared Neighborhood Hits	133
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

MYO1E_HUMAN
NC score	0.128924 (rank : 165)	θ value	0.00298849 (rank : 87)
Query Neighborhood Hits	409	Target Neighborhood Hits	293	Shared Neighborhood Hits	125
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

NGEF_HUMAN
NC score	0.127952 (rank : 166)	θ value	0.0252991 (rank : 116)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

RUSC1_HUMAN
NC score	0.127583 (rank : 167)	θ value	1.38821 (rank : 232)
Query Neighborhood Hits	409	Target Neighborhood Hits	226	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

NGEF_MOUSE
NC score	0.127554 (rank : 168)	θ value	0.0431538 (rank : 127)
Query Neighborhood Hits	409	Target Neighborhood Hits	228	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

NOXO1_MOUSE
NC score	0.126810 (rank : 169)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	409	Target Neighborhood Hits	114	Shared Neighborhood Hits	79
SwissProt Accessions	Q8VCM2, Q3TZA4, Q8BH41, Q9D747	Gene names	Noxo1, Snx28
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Sorting nexin-28).

NOXO1_HUMAN
NC score	0.126504 (rank : 170)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	409	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NFA2, Q86YM1, Q8NFA3, Q96B73	Gene names	NOXO1, P41NOX
Domain Architecture	No domain graphic available
Description	NADPH oxidase organizer 1 (Nox organizer 1) (Nox-organizing protein 1) (NADPH oxidase regulatory protein).

P85B_MOUSE
NC score	0.126267 (rank : 171)	θ value	0.62314 (rank : 187)
Query Neighborhood Hits	409	Target Neighborhood Hits	519	Shared Neighborhood Hits	62
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PLCG1_MOUSE
NC score	0.126180 (rank : 172)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	409	Target Neighborhood Hits	314	Shared Neighborhood Hits	118
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

RUSC1_MOUSE
NC score	0.122737 (rank : 173)	θ value	1.81305 (rank : 251)
Query Neighborhood Hits	409	Target Neighborhood Hits	206	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

LASP1_HUMAN
NC score	0.122541 (rank : 174)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	409	Target Neighborhood Hits	293	Shared Neighborhood Hits	109
SwissProt Accessions	Q14847, Q96ED2, Q96IG0	Gene names	LASP1, MLN50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

NPHP1_HUMAN
NC score	0.122101 (rank : 175)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	409	Target Neighborhood Hits	288	Shared Neighborhood Hits	97
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

PLCG1_HUMAN
NC score	0.121806 (rank : 176)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	409	Target Neighborhood Hits	293	Shared Neighborhood Hits	112
SwissProt Accessions	P19174, Q2V575	Gene names	PLCG1, PLC1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PLCG2_HUMAN
NC score	0.121219 (rank : 177)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	409	Target Neighborhood Hits	280	Shared Neighborhood Hits	109
SwissProt Accessions	P16885, Q969T5	Gene names	PLCG2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-2) (Phospholipase C-gamma-2) (PLC-IV).

LASP1_MOUSE
NC score	0.120655 (rank : 178)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	409	Target Neighborhood Hits	297	Shared Neighborhood Hits	108
SwissProt Accessions	Q61792, Q62416	Gene names	Lasp1, Mln50
Domain Architecture
Description	LIM and SH3 domain protein 1 (LASP-1) (MLN 50).

ARHGG_MOUSE
NC score	0.115132 (rank : 179)	θ value	2.36792 (rank : 260)
Query Neighborhood Hits	409	Target Neighborhood Hits	152	Shared Neighborhood Hits	61
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

NEBL_HUMAN
NC score	0.114751 (rank : 180)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	409	Target Neighborhood Hits	457	Shared Neighborhood Hits	114
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

SHAN2_MOUSE
NC score	0.113417 (rank : 181)	θ value	0.125558 (rank : 149)
Query Neighborhood Hits	409	Target Neighborhood Hits	446	Shared Neighborhood Hits	112
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

MBD6_HUMAN
NC score	0.112256 (rank : 182)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	409	Target Neighborhood Hits	349	Shared Neighborhood Hits	81
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

TAF4_HUMAN
NC score	0.111890 (rank : 183)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	409	Target Neighborhood Hits	687	Shared Neighborhood Hits	100
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CN032_MOUSE
NC score	0.110050 (rank : 184)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	409	Target Neighborhood Hits	233	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

ARHG5_HUMAN
NC score	0.109594 (rank : 185)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	409	Target Neighborhood Hits	172	Shared Neighborhood Hits	76
SwissProt Accessions	Q12774	Gene names	ARHGEF5, TIM
Domain Architecture
Description	Rho guanine nucleotide exchange factor 5 (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (p60 TIM) (Transforming immortalized mammary oncogene).

SMR3A_HUMAN
NC score	0.109390 (rank : 186)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	409	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

ARHGG_HUMAN
NC score	0.108792 (rank : 187)	θ value	0.0431538 (rank : 125)
Query Neighborhood Hits	409	Target Neighborhood Hits	129	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CN032_HUMAN
NC score	0.108716 (rank : 188)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	409	Target Neighborhood Hits	267	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CPSF6_HUMAN
NC score	0.107057 (rank : 189)	θ value	1.38821 (rank : 220)
Query Neighborhood Hits	409	Target Neighborhood Hits	359	Shared Neighborhood Hits	73
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
NC score	0.106836 (rank : 190)	θ value	1.38821 (rank : 221)
Query Neighborhood Hits	409	Target Neighborhood Hits	356	Shared Neighborhood Hits	73
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

ASPP2_HUMAN
NC score	0.105864 (rank : 191)	θ value	2.36792 (rank : 261)
Query Neighborhood Hits	409	Target Neighborhood Hits	1156	Shared Neighborhood Hits	150
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

TIAM1_HUMAN
NC score	0.105839 (rank : 192)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	409	Target Neighborhood Hits	225	Shared Neighborhood Hits	42
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ANM2_HUMAN
NC score	0.104306 (rank : 193)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	409	Target Neighborhood Hits	175	Shared Neighborhood Hits	94
SwissProt Accessions	P55345, P78350, Q9BW15, Q9UMC2	Gene names	PRMT2, HMT1, HRMT1L1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

NEBU_HUMAN
NC score	0.103826 (rank : 194)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	409	Target Neighborhood Hits	420	Shared Neighborhood Hits	117
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

PRP1_HUMAN
NC score	0.103099 (rank : 195)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	409	Target Neighborhood Hits	385	Shared Neighborhood Hits	87
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

ANM2_MOUSE
NC score	0.103061 (rank : 196)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	409	Target Neighborhood Hits	175	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R144	Gene names	Prmt2, Hrmt1l1
Domain Architecture
Description	Protein arginine N-methyltransferase 2 (EC 2.1.1.-).

PREX1_HUMAN
NC score	0.102822 (rank : 197)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	409	Target Neighborhood Hits	177	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

GSCR1_HUMAN
NC score	0.102446 (rank : 198)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	409	Target Neighborhood Hits	674	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SHAN1_HUMAN
NC score	0.101944 (rank : 199)	θ value	0.00869519 (rank : 101)
Query Neighborhood Hits	409	Target Neighborhood Hits	1041	Shared Neighborhood Hits	189
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PEX13_MOUSE
NC score	0.100869 (rank : 200)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	409	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D0K1, Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9EPK1	Gene names	Pex13
Domain Architecture	No domain graphic available
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

PEX13_HUMAN
NC score	0.100215 (rank : 201)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	409	Target Neighborhood Hits	128	Shared Neighborhood Hits	79
SwissProt Accessions	Q92968	Gene names	PEX13
Domain Architecture
Description	Peroxisomal membrane protein PEX13 (Peroxin-13).

SF3A2_HUMAN
NC score	0.099491 (rank : 202)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	409	Target Neighborhood Hits	263	Shared Neighborhood Hits	58
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WASIP_MOUSE
NC score	0.099106 (rank : 203)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	409	Target Neighborhood Hits	392	Shared Neighborhood Hits	100
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

BAT2_HUMAN
NC score	0.098647 (rank : 204)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	409	Target Neighborhood Hits	931	Shared Neighborhood Hits	140
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SF3A2_MOUSE
NC score	0.098260 (rank : 205)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	409	Target Neighborhood Hits	247	Shared Neighborhood Hits	54
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

WASIP_HUMAN
NC score	0.098230 (rank : 206)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	409	Target Neighborhood Hits	458	Shared Neighborhood Hits	101
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TIAM1_MOUSE
NC score	0.097776 (rank : 207)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	409	Target Neighborhood Hits	205	Shared Neighborhood Hits	37
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

GRP3_HUMAN
NC score	0.095891 (rank : 208)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	409	Target Neighborhood Hits	131	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

PRR12_HUMAN
NC score	0.095877 (rank : 209)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	409	Target Neighborhood Hits	460	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PKHG1_HUMAN
NC score	0.095401 (rank : 210)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	409	Target Neighborhood Hits	174	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ARHGA_HUMAN
NC score	0.094530 (rank : 211)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	409	Target Neighborhood Hits	187	Shared Neighborhood Hits	33
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

PI5PA_HUMAN
NC score	0.093632 (rank : 212)	θ value	0.0113563 (rank : 106)
Query Neighborhood Hits	409	Target Neighborhood Hits	749	Shared Neighborhood Hits	123
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RIMB2_MOUSE
NC score	0.093060 (rank : 213)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	409	Target Neighborhood Hits	246	Shared Neighborhood Hits	87
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ARHGA_MOUSE
NC score	0.092965 (rank : 214)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	409	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

RIMB2_HUMAN
NC score	0.091769 (rank : 215)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	409	Target Neighborhood Hits	263	Shared Neighborhood Hits	93
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ARHG3_HUMAN
NC score	0.091769 (rank : 216)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	409	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NR81, Q6NUN3, Q7Z4U2, Q7Z5T2, Q9H7T4	Gene names	ARHGEF3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN).

ARHG8_MOUSE
NC score	0.091706 (rank : 217)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	409	Target Neighborhood Hits	79	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z206, Q8C4I0, Q9Z1L7	Gene names	Net1, Arhgef8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (Rho guanine nucleotide exchange factor 8).

MUC7_HUMAN
NC score	0.091595 (rank : 218)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	409	Target Neighborhood Hits	538	Shared Neighborhood Hits	95
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

BAT2_MOUSE
NC score	0.091545 (rank : 219)	θ value	0.813845 (rank : 191)
Query Neighborhood Hits	409	Target Neighborhood Hits	947	Shared Neighborhood Hits	139
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ARHG3_MOUSE
NC score	0.091059 (rank : 220)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	409	Target Neighborhood Hits	85	Shared Neighborhood Hits	31
SwissProt Accessions	Q91X46, Q8CDM0, Q91VY4, Q99K14, Q9DC31	Gene names	Arhgef3
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 3.

PRB3_HUMAN
NC score	0.090621 (rank : 221)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	409	Target Neighborhood Hits	318	Shared Neighborhood Hits	69
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

P55G_HUMAN
NC score	0.090123 (rank : 222)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	409	Target Neighborhood Hits	451	Shared Neighborhood Hits	36
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

ALEX_HUMAN
NC score	0.090123 (rank : 223)	θ value	0.0431538 (rank : 123)
Query Neighborhood Hits	409	Target Neighborhood Hits	361	Shared Neighborhood Hits	64
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SNX18_HUMAN
NC score	0.090092 (rank : 224)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	409	Target Neighborhood Hits	207	Shared Neighborhood Hits	95
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

SNX18_MOUSE
NC score	0.088829 (rank : 225)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	409	Target Neighborhood Hits	198	Shared Neighborhood Hits	93
SwissProt Accessions	Q91ZR2	Gene names	Snag1, Snx18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

ARHG8_HUMAN
NC score	0.088799 (rank : 226)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	409	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

ARHGF_HUMAN
NC score	0.088355 (rank : 227)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	409	Target Neighborhood Hits	214	Shared Neighborhood Hits	61
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

ECT2_MOUSE
NC score	0.088329 (rank : 228)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	409	Target Neighborhood Hits	98	Shared Neighborhood Hits	30
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

P55G_MOUSE
NC score	0.088308 (rank : 229)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	409	Target Neighborhood Hits	401	Shared Neighborhood Hits	34
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

K1543_MOUSE
NC score	0.088065 (rank : 230)	θ value	0.00228821 (rank : 83)
Query Neighborhood Hits	409	Target Neighborhood Hits	497	Shared Neighborhood Hits	77
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

ECT2_HUMAN
NC score	0.087964 (rank : 231)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	409	Target Neighborhood Hits	98	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

WIRE_HUMAN
NC score	0.087381 (rank : 232)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	409	Target Neighborhood Hits	329	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

GGN_MOUSE
NC score	0.085240 (rank : 233)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	409	Target Neighborhood Hits	311	Shared Neighborhood Hits	71
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

WIRE_MOUSE
NC score	0.084211 (rank : 234)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	409	Target Neighborhood Hits	310	Shared Neighborhood Hits	76
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

GGN_HUMAN
NC score	0.083886 (rank : 235)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	409	Target Neighborhood Hits	269	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

DAPP1_MOUSE
NC score	0.083767 (rank : 236)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	409	Target Neighborhood Hits	225	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

MUC1_HUMAN
NC score	0.083738 (rank : 237)	θ value	1.09739e-05 (rank : 65)
Query Neighborhood Hits	409	Target Neighborhood Hits	975	Shared Neighborhood Hits	112
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SRRM1_MOUSE
NC score	0.083696 (rank : 238)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	409	Target Neighborhood Hits	966	Shared Neighborhood Hits	115
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

WBP11_HUMAN
NC score	0.083336 (rank : 239)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	409	Target Neighborhood Hits	354	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

CENB2_HUMAN
NC score	0.082312 (rank : 240)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	409	Target Neighborhood Hits	425	Shared Neighborhood Hits	31
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ENAH_MOUSE
NC score	0.082282 (rank : 241)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	409	Target Neighborhood Hits	919	Shared Neighborhood Hits	109
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

WBP11_MOUSE
NC score	0.081934 (rank : 242)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	409	Target Neighborhood Hits	362	Shared Neighborhood Hits	69
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

DAPP1_HUMAN
NC score	0.081910 (rank : 243)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

SPN90_HUMAN
NC score	0.081499 (rank : 244)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	409	Target Neighborhood Hits	157	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

SPTA2_HUMAN
NC score	0.081360 (rank : 245)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	409	Target Neighborhood Hits	888	Shared Neighborhood Hits	125
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

GNRP_MOUSE
NC score	0.081315 (rank : 246)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	409	Target Neighborhood Hits	191	Shared Neighborhood Hits	33
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

PI5PA_MOUSE
NC score	0.080790 (rank : 247)	θ value	5.27518 (rank : 340)
Query Neighborhood Hits	409	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RUSC2_HUMAN
NC score	0.080428 (rank : 248)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	409	Target Neighborhood Hits	205	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

RAPH1_HUMAN
NC score	0.080267 (rank : 249)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	409	Target Neighborhood Hits	593	Shared Neighborhood Hits	107
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RUSC2_MOUSE
NC score	0.080135 (rank : 250)	θ value	0.21417 (rank : 160)
Query Neighborhood Hits	409	Target Neighborhood Hits	305	Shared Neighborhood Hits	82
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

NACAM_MOUSE
NC score	0.079736 (rank : 251)	θ value	0.125558 (rank : 147)
Query Neighborhood Hits	409	Target Neighborhood Hits	1866	Shared Neighborhood Hits	185
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

FMNL_HUMAN
NC score	0.079624 (rank : 252)	θ value	0.0330416 (rank : 120)
Query Neighborhood Hits	409	Target Neighborhood Hits	529	Shared Neighborhood Hits	81
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

ZN207_HUMAN
NC score	0.079589 (rank : 253)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	409	Target Neighborhood Hits	326	Shared Neighborhood Hits	48
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

SRRM1_HUMAN
NC score	0.078577 (rank : 254)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	409	Target Neighborhood Hits	690	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CENB5_HUMAN
NC score	0.078551 (rank : 255)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	409	Target Neighborhood Hits	395	Shared Neighborhood Hits	26
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

FGD1_HUMAN
NC score	0.078052 (rank : 256)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	409	Target Neighborhood Hits	367	Shared Neighborhood Hits	73
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

OGFR_HUMAN
NC score	0.077669 (rank : 257)	θ value	0.365318 (rank : 169)
Query Neighborhood Hits	409	Target Neighborhood Hits	1582	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CIP4_HUMAN
NC score	0.077269 (rank : 258)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	409	Target Neighborhood Hits	374	Shared Neighborhood Hits	46
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

YLPM1_MOUSE
NC score	0.077088 (rank : 259)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	409	Target Neighborhood Hits	505	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

MCF2_HUMAN
NC score	0.076671 (rank : 260)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	32
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

GNRP_HUMAN
NC score	0.076187 (rank : 261)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	409	Target Neighborhood Hits	239	Shared Neighborhood Hits	35
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

CENB1_HUMAN
NC score	0.075695 (rank : 262)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	409	Target Neighborhood Hits	383	Shared Neighborhood Hits	30
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

RERE_HUMAN
NC score	0.075424 (rank : 263)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	409	Target Neighborhood Hits	779	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RGS3_MOUSE
NC score	0.075207 (rank : 264)	θ value	0.365318 (rank : 172)
Query Neighborhood Hits	409	Target Neighborhood Hits	1621	Shared Neighborhood Hits	179
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ES8L3_MOUSE
NC score	0.074925 (rank : 265)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	409	Target Neighborhood Hits	168	Shared Neighborhood Hits	85
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

PELP1_MOUSE
NC score	0.074070 (rank : 266)	θ value	1.38821 (rank : 230)
Query Neighborhood Hits	409	Target Neighborhood Hits	709	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

MCF2L_MOUSE
NC score	0.073763 (rank : 267)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	409	Target Neighborhood Hits	255	Shared Neighborhood Hits	44
SwissProt Accessions	Q64096	Gene names	Mcf2l, Dbs
Domain Architecture
Description	Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2- transforming sequence-like protein).

SMR3B_HUMAN
NC score	0.073580 (rank : 268)	θ value	1.38821 (rank : 234)
Query Neighborhood Hits	409	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SPTA1_MOUSE
NC score	0.073190 (rank : 269)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	409	Target Neighborhood Hits	675	Shared Neighborhood Hits	115
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

BSN_MOUSE
NC score	0.073099 (rank : 270)	θ value	1.81305 (rank : 241)
Query Neighborhood Hits	409	Target Neighborhood Hits	2057	Shared Neighborhood Hits	180
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ATN1_HUMAN
NC score	0.073073 (rank : 271)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	409	Target Neighborhood Hits	676	Shared Neighborhood Hits	102
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SON_HUMAN
NC score	0.072873 (rank : 272)	θ value	0.00390308 (rank : 91)
Query Neighborhood Hits	409	Target Neighborhood Hits	1568	Shared Neighborhood Hits	169
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

FGD1_MOUSE
NC score	0.072698 (rank : 273)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	409	Target Neighborhood Hits	387	Shared Neighborhood Hits	84
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SFR15_HUMAN
NC score	0.072611 (rank : 274)	θ value	3.0926 (rank : 297)
Query Neighborhood Hits	409	Target Neighborhood Hits	368	Shared Neighborhood Hits	69
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

PCLO_MOUSE
NC score	0.072552 (rank : 275)	θ value	6.88961 (rank : 374)
Query Neighborhood Hits	409	Target Neighborhood Hits	2275	Shared Neighborhood Hits	197
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRR13_MOUSE
NC score	0.072407 (rank : 276)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	409	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PAF49_HUMAN
NC score	0.071756 (rank : 277)	θ value	0.0961366 (rank : 143)
Query Neighborhood Hits	409	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

PCLO_HUMAN
NC score	0.071747 (rank : 278)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	409	Target Neighborhood Hits	2046	Shared Neighborhood Hits	175
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRG4_HUMAN
NC score	0.070972 (rank : 279)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	409	Target Neighborhood Hits	764	Shared Neighborhood Hits	106
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

YLPM1_HUMAN
NC score	0.070051 (rank : 280)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	409	Target Neighborhood Hits	670	Shared Neighborhood Hits	94
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

PRB4S_HUMAN
NC score	0.070020 (rank : 281)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	409	Target Neighborhood Hits	330	Shared Neighborhood Hits	71
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

TCRG1_MOUSE
NC score	0.069890 (rank : 282)	θ value	5.27518 (rank : 346)
Query Neighborhood Hits	409	Target Neighborhood Hits	947	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

RGNEF_MOUSE
NC score	0.069829 (rank : 283)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	409	Target Neighborhood Hits	641	Shared Neighborhood Hits	54
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

FGD4_MOUSE
NC score	0.069727 (rank : 284)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	409	Target Neighborhood Hits	227	Shared Neighborhood Hits	38
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

BCL9_HUMAN
NC score	0.069607 (rank : 285)	θ value	0.163984 (rank : 153)
Query Neighborhood Hits	409	Target Neighborhood Hits	1008	Shared Neighborhood Hits	138
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BIN1_MOUSE
NC score	0.069601 (rank : 286)	θ value	6.88961 (rank : 352)
Query Neighborhood Hits	409	Target Neighborhood Hits	283	Shared Neighborhood Hits	86
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

SPTA1_HUMAN
NC score	0.069463 (rank : 287)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	409	Target Neighborhood Hits	748	Shared Neighborhood Hits	118
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

FGD3_MOUSE
NC score	0.069409 (rank : 288)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	409	Target Neighborhood Hits	257	Shared Neighborhood Hits	39
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

SPN90_MOUSE
NC score	0.068890 (rank : 289)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	409	Target Neighborhood Hits	157	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

CS016_HUMAN
NC score	0.068833 (rank : 290)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	409	Target Neighborhood Hits	310	Shared Neighborhood Hits	63
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

FGD4_HUMAN
NC score	0.068783 (rank : 291)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	409	Target Neighborhood Hits	219	Shared Neighborhood Hits	38
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

SNX22_HUMAN
NC score	0.068212 (rank : 292)	θ value	0.0563607 (rank : 132)
Query Neighborhood Hits	409	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q96L94, Q9H844	Gene names	SNX22
Domain Architecture
Description	Sorting nexin-22.

MLL2_HUMAN
NC score	0.068091 (rank : 293)	θ value	8.99809 (rank : 398)
Query Neighborhood Hits	409	Target Neighborhood Hits	1788	Shared Neighborhood Hits	178
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SHLB2_MOUSE
NC score	0.067835 (rank : 294)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	409	Target Neighborhood Hits	88	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R3V5, Q8K140, Q91ZI7	Gene names	Sh3glb2, Kiaa1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

SHLB2_HUMAN
NC score	0.067822 (rank : 295)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	409	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NR46, Q8WY61, Q96JH9	Gene names	SH3GLB2, KIAA1848
Domain Architecture
Description	SH3 domain GRB2-like protein B2 (Endophilin-B2).

ARHG1_HUMAN
NC score	0.067719 (rank : 296)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	409	Target Neighborhood Hits	176	Shared Neighborhood Hits	48
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ARHGB_HUMAN
NC score	0.066839 (rank : 297)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	409	Target Neighborhood Hits	375	Shared Neighborhood Hits	49
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SYNJ1_HUMAN
NC score	0.066623 (rank : 298)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	409	Target Neighborhood Hits	498	Shared Neighborhood Hits	92
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SRRM2_HUMAN
NC score	0.066429 (rank : 299)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	409	Target Neighborhood Hits	1296	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PDZD8_HUMAN
NC score	0.066279 (rank : 300)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	409	Target Neighborhood Hits	185	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

SYNJ1_MOUSE
NC score	0.066237 (rank : 301)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	409	Target Neighborhood Hits	516	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ALO17_HUMAN
NC score	0.065806 (rank : 302)	θ value	0.0961366 (rank : 139)
Query Neighborhood Hits	409	Target Neighborhood Hits	317	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

MISS_MOUSE
NC score	0.065779 (rank : 303)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	409	Target Neighborhood Hits	444	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

AMPH_HUMAN
NC score	0.065744 (rank : 304)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	409	Target Neighborhood Hits	455	Shared Neighborhood Hits	101
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

WASL_MOUSE
NC score	0.065608 (rank : 305)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	409	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RERE_MOUSE
NC score	0.065381 (rank : 306)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	409	Target Neighborhood Hits	785	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MAGE1_HUMAN
NC score	0.065171 (rank : 307)	θ value	5.44631e-05 (rank : 67)
Query Neighborhood Hits	409	Target Neighborhood Hits	1389	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

FGD2_HUMAN
NC score	0.065053 (rank : 308)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	409	Target Neighborhood Hits	151	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

TCRG1_HUMAN
NC score	0.064949 (rank : 309)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	409	Target Neighborhood Hits	929	Shared Neighborhood Hits	67
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

UN13A_HUMAN
NC score	0.064839 (rank : 310)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	409	Target Neighborhood Hits	285	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

FGD3_HUMAN
NC score	0.064495 (rank : 311)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	409	Target Neighborhood Hits	249	Shared Neighborhood Hits	42
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

BCL9_MOUSE
NC score	0.064189 (rank : 312)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	409	Target Neighborhood Hits	770	Shared Neighborhood Hits	125
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

EPS8_HUMAN
NC score	0.064013 (rank : 313)	θ value	2.36792 (rank : 270)
Query Neighborhood Hits	409	Target Neighborhood Hits	151	Shared Neighborhood Hits	79
SwissProt Accessions	Q12929, Q8N6J0	Gene names	EPS8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

NCOA6_HUMAN
NC score	0.063964 (rank : 314)	θ value	3.0926 (rank : 291)
Query Neighborhood Hits	409	Target Neighborhood Hits	1202	Shared Neighborhood Hits	139
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BI2L1_HUMAN
NC score	0.063871 (rank : 315)	θ value	1.81305 (rank : 240)
Query Neighborhood Hits	409	Target Neighborhood Hits	156	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

EPS8_MOUSE
NC score	0.063862 (rank : 316)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	409	Target Neighborhood Hits	157	Shared Neighborhood Hits	83
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

BIN1_HUMAN
NC score	0.063551 (rank : 317)	θ value	6.88961 (rank : 351)
Query Neighborhood Hits	409	Target Neighborhood Hits	335	Shared Neighborhood Hits	90
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

RIMB1_HUMAN
NC score	0.063358 (rank : 318)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	409	Target Neighborhood Hits	1479	Shared Neighborhood Hits	163
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BAT3_MOUSE
NC score	0.063343 (rank : 319)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	409	Target Neighborhood Hits	518	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

FGD6_MOUSE
NC score	0.063307 (rank : 320)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	409	Target Neighborhood Hits	282	Shared Neighborhood Hits	46
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

MYO15_HUMAN
NC score	0.063286 (rank : 321)	θ value	8.99809 (rank : 399)
Query Neighborhood Hits	409	Target Neighborhood Hits	671	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CENG1_MOUSE
NC score	0.063175 (rank : 322)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	409	Target Neighborhood Hits	531	Shared Neighborhood Hits	54
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

FA13A_MOUSE
NC score	0.063139 (rank : 323)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	409	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

ARHG1_MOUSE
NC score	0.063133 (rank : 324)	θ value	2.36792 (rank : 259)
Query Neighborhood Hits	409	Target Neighborhood Hits	266	Shared Neighborhood Hits	55
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

UN13B_HUMAN
NC score	0.062679 (rank : 325)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	409	Target Neighborhood Hits	217	Shared Neighborhood Hits	29
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ES8L3_HUMAN
NC score	0.062650 (rank : 326)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	409	Target Neighborhood Hits	206	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

CSF1_HUMAN
NC score	0.062503 (rank : 327)	θ value	0.0113563 (rank : 103)
Query Neighborhood Hits	409	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CN155_HUMAN
NC score	0.062406 (rank : 328)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	409	Target Neighborhood Hits	385	Shared Neighborhood Hits	65
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

FA13A_HUMAN
NC score	0.062363 (rank : 329)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	409	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

SHLB1_MOUSE
NC score	0.062123 (rank : 330)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	409	Target Neighborhood Hits	101	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JK48, Q8CDS9, Q8VI52, Q9CT31	Gene names	Sh3glb1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1).

FGD2_MOUSE
NC score	0.062071 (rank : 331)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	409	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

ARHGC_HUMAN
NC score	0.062048 (rank : 332)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	409	Target Neighborhood Hits	351	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BSN_HUMAN
NC score	0.061910 (rank : 333)	θ value	2.36792 (rank : 262)
Query Neighborhood Hits	409	Target Neighborhood Hits	1537	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

T22D2_HUMAN
NC score	0.061779 (rank : 334)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	409	Target Neighborhood Hits	250	Shared Neighborhood Hits	48
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

SF01_HUMAN
NC score	0.061678 (rank : 335)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	409	Target Neighborhood Hits	287	Shared Neighborhood Hits	58
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SHLB1_HUMAN
NC score	0.061553 (rank : 336)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	409	Target Neighborhood Hits	96	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y371, Q9H3Z0, Q9NR47, Q9NYA9	Gene names	SH3GLB1
Domain Architecture
Description	SH3 domain GRB2-like protein B1 (EC 2.3.1.-) (Endophilin-B1) (Bax- interacting factor 1) (Bif-1).

MYO15_MOUSE
NC score	0.061245 (rank : 337)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	409	Target Neighborhood Hits	467	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

FMN2_HUMAN
NC score	0.061161 (rank : 338)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	409	Target Neighborhood Hits	484	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

WASF2_MOUSE
NC score	0.061072 (rank : 339)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	409	Target Neighborhood Hits	315	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ARHG2_HUMAN
NC score	0.060954 (rank : 340)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	409	Target Neighborhood Hits	142	Shared Neighborhood Hits	35
SwissProt Accessions	Q92974, O75142, Q15079	Gene names	ARHGEF2, KIAA0651, LFP40
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (GEF-H1 protein) (Proliferating cell nucleolar antigen p40).

DDFL1_HUMAN
NC score	0.060931 (rank : 341)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	409	Target Neighborhood Hits	353	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

AMPH_MOUSE
NC score	0.060856 (rank : 342)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	409	Target Neighborhood Hits	291	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

RIMB1_MOUSE
NC score	0.060800 (rank : 343)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	409	Target Neighborhood Hits	1376	Shared Neighborhood Hits	148
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RASA1_HUMAN
NC score	0.060710 (rank : 344)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	409	Target Neighborhood Hits	258	Shared Neighborhood Hits	40
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

ARHGC_MOUSE
NC score	0.060696 (rank : 345)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	409	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CSKI2_HUMAN
NC score	0.060522 (rank : 346)	θ value	6.88961 (rank : 359)
Query Neighborhood Hits	409	Target Neighborhood Hits	747	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DOT1L_HUMAN
NC score	0.060344 (rank : 347)	θ value	2.36792 (rank : 268)
Query Neighborhood Hits	409	Target Neighborhood Hits	660	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

CIC_HUMAN
NC score	0.060120 (rank : 348)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	409	Target Neighborhood Hits	992	Shared Neighborhood Hits	136
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SYN1_HUMAN
NC score	0.060059 (rank : 349)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	409	Target Neighborhood Hits	419	Shared Neighborhood Hits	92
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

ALEX_MOUSE
NC score	0.059772 (rank : 350)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	409	Target Neighborhood Hits	197	Shared Neighborhood Hits	47
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SRRM2_MOUSE
NC score	0.059733 (rank : 351)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	409	Target Neighborhood Hits	1470	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DOCK1_HUMAN
NC score	0.059683 (rank : 352)	θ value	2.36792 (rank : 267)
Query Neighborhood Hits	409	Target Neighborhood Hits	191	Shared Neighborhood Hits	83
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

ARHG2_MOUSE
NC score	0.059376 (rank : 353)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	409	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	Q60875, O09115	Gene names	Arhgef2, Lbcl1, Lfc
Domain Architecture
Description	Rho/Rac guanine nucleotide exchange factor 2 (Lymphoid blast crisis- like 1) (LBC'S first cousin) (Oncogene LFC) (RHOBIN).

UN13B_MOUSE
NC score	0.059352 (rank : 354)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	409	Target Neighborhood Hits	210	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

FMNL_MOUSE
NC score	0.059351 (rank : 355)	θ value	6.88961 (rank : 362)
Query Neighborhood Hits	409	Target Neighborhood Hits	428	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

CCNK_MOUSE
NC score	0.059280 (rank : 356)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	409	Target Neighborhood Hits	350	Shared Neighborhood Hits	71
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CSKI2_MOUSE
NC score	0.059037 (rank : 357)	θ value	4.03905 (rank : 307)
Query Neighborhood Hits	409	Target Neighborhood Hits	812	Shared Neighborhood Hits	126
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

RGS3_HUMAN
NC score	0.058804 (rank : 358)	θ value	0.365318 (rank : 171)
Query Neighborhood Hits	409	Target Neighborhood Hits	1375	Shared Neighborhood Hits	145
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

FGD6_HUMAN
NC score	0.058749 (rank : 359)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	409	Target Neighborhood Hits	237	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

CENG1_HUMAN
NC score	0.058613 (rank : 360)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	409	Target Neighborhood Hits	544	Shared Neighborhood Hits	49
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

WASL_HUMAN
NC score	0.058542 (rank : 361)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	409	Target Neighborhood Hits	312	Shared Neighborhood Hits	66
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

PRR13_HUMAN
NC score	0.058268 (rank : 362)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	409	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

TARSH_HUMAN
NC score	0.058103 (rank : 363)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	409	Target Neighborhood Hits	768	Shared Neighborhood Hits	97
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

WASF2_HUMAN
NC score	0.058004 (rank : 364)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	409	Target Neighborhood Hits	280	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

SNX9_HUMAN
NC score	0.057992 (rank : 365)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	409	Target Neighborhood Hits	148	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y5X1, Q9BSI7, Q9BVM1, Q9UJH6, Q9UP20	Gene names	SNX9, SH3PX1
Domain Architecture
Description	Sorting nexin-9 (SH3 and PX domain-containing protein 1) (SDP1 protein).

MYO10_HUMAN
NC score	0.057875 (rank : 366)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	409	Target Neighborhood Hits	920	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SFPQ_MOUSE
NC score	0.057718 (rank : 367)	θ value	8.99809 (rank : 406)
Query Neighborhood Hits	409	Target Neighborhood Hits	958	Shared Neighborhood Hits	116
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

PRRT3_HUMAN
NC score	0.057680 (rank : 368)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	409	Target Neighborhood Hits	998	Shared Neighborhood Hits	131
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

FARP2_MOUSE
NC score	0.057661 (rank : 369)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	409	Target Neighborhood Hits	209	Shared Neighborhood Hits	42
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

ES8L1_MOUSE
NC score	0.057287 (rank : 370)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	409	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

PCTL_MOUSE
NC score	0.057254 (rank : 371)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	409	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

STS2_HUMAN
NC score	0.056935 (rank : 372)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	409	Target Neighborhood Hits	108	Shared Neighborhood Hits	66
SwissProt Accessions	P57075, Q6HA34, Q6HA35, Q6ISI6, Q6ISK3, Q6ISS9	Gene names	UBASH3A, STS2
Domain Architecture
Description	Suppressor of T-cell receptor signaling 2 (STS-2) (Cbl-interacting protein 4) (CLIP4) (T-cell ubiquitin ligand) (TULA).

PCTL_HUMAN
NC score	0.056599 (rank : 373)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	409	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

MDC1_HUMAN
NC score	0.056535 (rank : 374)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	409	Target Neighborhood Hits	1446	Shared Neighborhood Hits	124
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MLL4_HUMAN
NC score	0.056432 (rank : 375)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	409	Target Neighborhood Hits	722	Shared Neighborhood Hits	110
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

M3K11_HUMAN
NC score	0.056424 (rank : 376)	θ value	0.00665767 (rank : 97)
Query Neighborhood Hits	409	Target Neighborhood Hits	1136	Shared Neighborhood Hits	161
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

RSMN_HUMAN
NC score	0.056280 (rank : 377)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	409	Target Neighborhood Hits	110	Shared Neighborhood Hits	31
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
NC score	0.056280 (rank : 378)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	409	Target Neighborhood Hits	110	Shared Neighborhood Hits	31
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

WBS14_HUMAN
NC score	0.055856 (rank : 379)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	409	Target Neighborhood Hits	273	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

TACC3_HUMAN
NC score	0.055725 (rank : 380)	θ value	0.0148317 (rank : 110)
Query Neighborhood Hits	409	Target Neighborhood Hits	779	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

SYN1_MOUSE
NC score	0.055682 (rank : 381)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	409	Target Neighborhood Hits	363	Shared Neighborhood Hits	72
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

DDFL1_MOUSE
NC score	0.055417 (rank : 382)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	409	Target Neighborhood Hits	324	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

PELP1_HUMAN
NC score	0.055260 (rank : 383)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	409	Target Neighborhood Hits	596	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CABIN_HUMAN
NC score	0.054997 (rank : 384)	θ value	6.88961 (rank : 353)
Query Neighborhood Hits	409	Target Neighborhood Hits	490	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

SFPQ_HUMAN
NC score	0.054847 (rank : 385)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	409	Target Neighborhood Hits	986	Shared Neighborhood Hits	116
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

FARP2_HUMAN
NC score	0.054329 (rank : 386)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	409	Target Neighborhood Hits	240	Shared Neighborhood Hits	44
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

M3K9_HUMAN
NC score	0.054251 (rank : 387)	θ value	0.00020696 (rank : 70)
Query Neighborhood Hits	409	Target Neighborhood Hits	1123	Shared Neighborhood Hits	133
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

ES8L2_HUMAN
NC score	0.054178 (rank : 388)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	409	Target Neighborhood Hits	193	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H6S3, Q53GM8, Q8WYW7, Q96K06, Q9H6K9	Gene names	EPS8L2, EPS8R2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

PRRT1_HUMAN
NC score	0.054098 (rank : 389)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	409	Target Neighborhood Hits	94	Shared Neighborhood Hits	27
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

SLAP2_MOUSE
NC score	0.053912 (rank : 390)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	409	Target Neighborhood Hits	136	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

NFH_MOUSE
NC score	0.053909 (rank : 391)	θ value	0.000786445 (rank : 71)
Query Neighborhood Hits	409	Target Neighborhood Hits	2247	Shared Neighborhood Hits	164
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRRT1_MOUSE
NC score	0.053796 (rank : 392)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	409	Target Neighborhood Hits	102	Shared Neighborhood Hits	29
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

SC24D_HUMAN
NC score	0.053754 (rank : 393)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	409	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SHD_MOUSE
NC score	0.053707 (rank : 394)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	409	Target Neighborhood Hits	137	Shared Neighborhood Hits	29
SwissProt Accessions	O88834, Q3SYI7	Gene names	Shd
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

CO039_HUMAN
NC score	0.053667 (rank : 395)	θ value	1.06291 (rank : 206)
Query Neighborhood Hits	409	Target Neighborhood Hits	264	Shared Neighborhood Hits	57
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

PYGO2_HUMAN
NC score	0.053645 (rank : 396)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	409	Target Neighborhood Hits	189	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

NCOA6_MOUSE
NC score	0.053626 (rank : 397)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	409	Target Neighborhood Hits	1076	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SON_MOUSE
NC score	0.053497 (rank : 398)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	409	Target Neighborhood Hits	957	Shared Neighborhood Hits	109
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

K1543_HUMAN
NC score	0.053183 (rank : 399)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	409	Target Neighborhood Hits	435	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

HAPIP_HUMAN
NC score	0.053154 (rank : 400)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	409	Target Neighborhood Hits	350	Shared Neighborhood Hits	31
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

SMR1_MOUSE
NC score	0.052886 (rank : 401)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	409	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SET1A_HUMAN
NC score	0.052667 (rank : 402)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	409	Target Neighborhood Hits	690	Shared Neighborhood Hits	91
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CCD1A_HUMAN
NC score	0.052666 (rank : 403)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	409	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P1N0, Q7Z435, Q86XV0, Q8NF89, Q9H603, Q9NXI1	Gene names	CC2D1A
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B- activating protein 023N).

WASF4_HUMAN
NC score	0.052637 (rank : 404)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	409	Target Neighborhood Hits	282	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

SASH1_HUMAN
NC score	0.052581 (rank : 405)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	409	Target Neighborhood Hits	292	Shared Neighborhood Hits	91
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

AB1IP_HUMAN
NC score	0.052538 (rank : 406)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	409	Target Neighborhood Hits	213	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

SMAP1_HUMAN
NC score	0.052164 (rank : 407)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	409	Target Neighborhood Hits	98	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

FA13C_HUMAN
NC score	0.052154 (rank : 408)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	409	Target Neighborhood Hits	94	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

REXO1_MOUSE
NC score	0.052077 (rank : 409)	θ value	0.0193708 (rank : 112)
Query Neighborhood Hits	409	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

TAB3_MOUSE
NC score	0.052071 (rank : 410)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	409	Target Neighborhood Hits	273	Shared Neighborhood Hits	41
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

SMP1L_HUMAN
NC score	0.051979 (rank : 411)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	409	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMAP1_MOUSE
NC score	0.051962 (rank : 412)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	409	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

MDC1_MOUSE
NC score	0.051808 (rank : 413)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	409	Target Neighborhood Hits	998	Shared Neighborhood Hits	103
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SMP1L_MOUSE
NC score	0.051804 (rank : 414)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	409	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SF01_MOUSE
NC score	0.051735 (rank : 415)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	409	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ZIM10_HUMAN
NC score	0.051691 (rank : 416)	θ value	0.125558 (rank : 151)
Query Neighborhood Hits	409	Target Neighborhood Hits	577	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

SH22A_HUMAN
NC score	0.051598 (rank : 417)	θ value	3.0926 (rank : 298)
Query Neighborhood Hits	409	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

CENA2_HUMAN
NC score	0.051406 (rank : 418)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	409	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CSKI1_HUMAN
NC score	0.051401 (rank : 419)	θ value	8.99809 (rank : 390)
Query Neighborhood Hits	409	Target Neighborhood Hits	997	Shared Neighborhood Hits	154
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ARI1B_HUMAN
NC score	0.051384 (rank : 420)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	409	Target Neighborhood Hits	567	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

DGKH_HUMAN
NC score	0.051335 (rank : 421)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	409	Target Neighborhood Hits	255	Shared Neighborhood Hits	30
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

ES8L2_MOUSE
NC score	0.051333 (rank : 422)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	409	Target Neighborhood Hits	169	Shared Neighborhood Hits	72
SwissProt Accessions	Q99K30, Q91VT7	Gene names	Eps8l2, Eps8r2
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 2 (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-like protein 2).

SOS1_HUMAN
NC score	0.051195 (rank : 423)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	409	Target Neighborhood Hits	274	Shared Neighborhood Hits	50
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SC24C_HUMAN
NC score	0.051037 (rank : 424)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	409	Target Neighborhood Hits	662	Shared Neighborhood Hits	83
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ARI1A_HUMAN
NC score	0.050985 (rank : 425)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	409	Target Neighborhood Hits	787	Shared Neighborhood Hits	110
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

FARP1_HUMAN
NC score	0.050920 (rank : 426)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	409	Target Neighborhood Hits	241	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

SH21A_HUMAN
NC score	0.050830 (rank : 427)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	409	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	O60880, O95383, O95384, O95385, O95386, Q9UNR0	Gene names	SH2D1A, DSHP, SAP
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP) (Duncan disease SH2-protein).

M3KL4_HUMAN
NC score	0.050724 (rank : 428)	θ value	0.0961366 (rank : 142)
Query Neighborhood Hits	409	Target Neighborhood Hits	1087	Shared Neighborhood Hits	125
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MYO7A_MOUSE
NC score	0.050607 (rank : 429)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	409	Target Neighborhood Hits	235	Shared Neighborhood Hits	23
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

SHB_MOUSE
NC score	0.050546 (rank : 430)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	409	Target Neighborhood Hits	137	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PD21, Q3ULM3	Gene names	Shb
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

ES8L1_HUMAN
NC score	0.050460 (rank : 431)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	409	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

IL3RB_MOUSE
NC score	0.050459 (rank : 432)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	409	Target Neighborhood Hits	355	Shared Neighborhood Hits	61
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IL3B2_MOUSE
NC score	0.050397 (rank : 433)	θ value	0.813845 (rank : 197)
Query Neighborhood Hits	409	Target Neighborhood Hits	372	Shared Neighborhood Hits	65
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

SELPL_MOUSE
NC score	0.050195 (rank : 434)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	409	Target Neighborhood Hits	588	Shared Neighborhood Hits	73
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SH21A_MOUSE
NC score	0.050192 (rank : 435)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	409	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	O88890, Q9QWV6	Gene names	Sh2d1a, Xlp
Domain Architecture
Description	SH2 domain protein 1A (Signaling lymphocyte activation molecule- associated protein) (SLAM-associated protein) (T cell signal transduction molecule SAP).

BI2L1_MOUSE
NC score	0.050161 (rank : 436)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	409	Target Neighborhood Hits	197	Shared Neighborhood Hits	49
SwissProt Accessions	Q9DBJ3	Gene names	Baiap2l1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

NU214_HUMAN
NC score	0.050104 (rank : 437)	θ value	6.88961 (rank : 373)
Query Neighborhood Hits	409	Target Neighborhood Hits	657	Shared Neighborhood Hits	76
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

CSPG5_MOUSE
NC score	0.049496 (rank : 438)	θ value	0.279714 (rank : 162)
Query Neighborhood Hits	409	Target Neighborhood Hits	211	Shared Neighborhood Hits	24
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

PP1RA_HUMAN
NC score	0.048742 (rank : 439)	θ value	4.03905 (rank : 315)
Query Neighborhood Hits	409	Target Neighborhood Hits	180	Shared Neighborhood Hits	46
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

SSBP4_HUMAN
NC score	0.048528 (rank : 440)	θ value	4.03905 (rank : 318)
Query Neighborhood Hits	409	Target Neighborhood Hits	753	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ZN385_HUMAN
NC score	0.048508 (rank : 441)	θ value	1.06291 (rank : 213)
Query Neighborhood Hits	409	Target Neighborhood Hits	614	Shared Neighborhood Hits	88
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SYNPO_MOUSE
NC score	0.047135 (rank : 442)	θ value	0.365318 (rank : 173)
Query Neighborhood Hits	409	Target Neighborhood Hits	242	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SAPS1_HUMAN
NC score	0.045837 (rank : 443)	θ value	1.81305 (rank : 252)
Query Neighborhood Hits	409	Target Neighborhood Hits	704	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

K1802_MOUSE
NC score	0.045528 (rank : 444)	θ value	0.62314 (rank : 184)
Query Neighborhood Hits	409	Target Neighborhood Hits	1596	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CI079_HUMAN
NC score	0.045371 (rank : 445)	θ value	0.813845 (rank : 192)
Query Neighborhood Hits	409	Target Neighborhood Hits	288	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

MIA2_MOUSE
NC score	0.045244 (rank : 446)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	409	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

DMRTD_MOUSE
NC score	0.044928 (rank : 447)	θ value	0.21417 (rank : 158)
Query Neighborhood Hits	409	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

MINT_MOUSE
NC score	0.044889 (rank : 448)	θ value	6.88961 (rank : 370)
Query Neighborhood Hits	409	Target Neighborhood Hits	1514	Shared Neighborhood Hits	123
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

COHA1_MOUSE
NC score	0.044023 (rank : 449)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	409	Target Neighborhood Hits	414	Shared Neighborhood Hits	75
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

SMOO_HUMAN
NC score	0.043953 (rank : 450)	θ value	1.38821 (rank : 233)
Query Neighborhood Hits	409	Target Neighborhood Hits	391	Shared Neighborhood Hits	67
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CO3A1_MOUSE
NC score	0.043583 (rank : 451)	θ value	8.99809 (rank : 387)
Query Neighborhood Hits	409	Target Neighborhood Hits	466	Shared Neighborhood Hits	76
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO1A1_HUMAN
NC score	0.043538 (rank : 452)	θ value	8.99809 (rank : 386)
Query Neighborhood Hits	409	Target Neighborhood Hits	475	Shared Neighborhood Hits	83
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

TAU_MOUSE
NC score	0.042501 (rank : 453)	θ value	4.03905 (rank : 320)
Query Neighborhood Hits	409	Target Neighborhood Hits	502	Shared Neighborhood Hits	73
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

EDA_HUMAN
NC score	0.042104 (rank : 454)	θ value	1.38821 (rank : 222)
Query Neighborhood Hits	409	Target Neighborhood Hits	134	Shared Neighborhood Hits	43
SwissProt Accessions	Q92838, O75910, Q5JUM7, Q9UP77, Q9Y6L0, Q9Y6L1, Q9Y6L2, Q9Y6L3, Q9Y6L4	Gene names	EDA, ED1
Domain Architecture
Description	Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

DOK7_MOUSE
NC score	0.042037 (rank : 455)	θ value	0.21417 (rank : 159)
Query Neighborhood Hits	409	Target Neighborhood Hits	169	Shared Neighborhood Hits	30
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

CO1A2_MOUSE
NC score	0.041687 (rank : 456)	θ value	2.36792 (rank : 264)
Query Neighborhood Hits	409	Target Neighborhood Hits	388	Shared Neighborhood Hits	69
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO5A1_HUMAN
NC score	0.041626 (rank : 457)	θ value	3.0926 (rank : 282)
Query Neighborhood Hits	409	Target Neighborhood Hits	434	Shared Neighborhood Hits	77
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

APXL_HUMAN
NC score	0.041580 (rank : 458)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	409	Target Neighborhood Hits	553	Shared Neighborhood Hits	64
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CJ108_HUMAN
NC score	0.041380 (rank : 459)	θ value	1.38821 (rank : 218)
Query Neighborhood Hits	409	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CO5A1_MOUSE
NC score	0.041193 (rank : 460)	θ value	8.99809 (rank : 388)
Query Neighborhood Hits	409	Target Neighborhood Hits	419	Shared Neighborhood Hits	73
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

RANB3_MOUSE
NC score	0.041175 (rank : 461)	θ value	0.125558 (rank : 148)
Query Neighborhood Hits	409	Target Neighborhood Hits	123	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

EDA_MOUSE
NC score	0.040981 (rank : 462)	θ value	1.38821 (rank : 223)
Query Neighborhood Hits	409	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

STON1_MOUSE
NC score	0.040716 (rank : 463)	θ value	0.62314 (rank : 189)
Query Neighborhood Hits	409	Target Neighborhood Hits	50	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

CEP68_MOUSE
NC score	0.040615 (rank : 464)	θ value	0.0961366 (rank : 141)
Query Neighborhood Hits	409	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

COHA1_HUMAN
NC score	0.040016 (rank : 465)	θ value	3.0926 (rank : 283)
Query Neighborhood Hits	409	Target Neighborhood Hits	400	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

NRX2B_HUMAN
NC score	0.039553 (rank : 466)	θ value	5.27518 (rank : 338)
Query Neighborhood Hits	409	Target Neighborhood Hits	481	Shared Neighborhood Hits	86
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

HAIR_HUMAN
NC score	0.039473 (rank : 467)	θ value	0.365318 (rank : 167)
Query Neighborhood Hits	409	Target Neighborhood Hits	172	Shared Neighborhood Hits	32
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

CO4A3_HUMAN
NC score	0.039136 (rank : 468)	θ value	0.365318 (rank : 166)
Query Neighborhood Hits	409	Target Neighborhood Hits	421	Shared Neighborhood Hits	76
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

GNAS1_MOUSE
NC score	0.038956 (rank : 469)	θ value	0.813845 (rank : 196)
Query Neighborhood Hits	409	Target Neighborhood Hits	651	Shared Neighborhood Hits	101
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CO4A4_HUMAN
NC score	0.038901 (rank : 470)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	409	Target Neighborhood Hits	440	Shared Neighborhood Hits	82
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

NUP53_MOUSE
NC score	0.038901 (rank : 471)	θ value	1.38821 (rank : 229)
Query Neighborhood Hits	409	Target Neighborhood Hits	94	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4R6, Q9D7J2	Gene names	Nup35, Mp44, Nup53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

GRIN1_MOUSE
NC score	0.038613 (rank : 472)	θ value	5.27518 (rank : 331)
Query Neighborhood Hits	409	Target Neighborhood Hits	337	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

S23IP_MOUSE
NC score	0.038541 (rank : 473)	θ value	8.99809 (rank : 405)
Query Neighborhood Hits	409	Target Neighborhood Hits	363	Shared Neighborhood Hits	53
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

NCOR1_HUMAN
NC score	0.038453 (rank : 474)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	409	Target Neighborhood Hits	577	Shared Neighborhood Hits	52
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

COBA1_HUMAN
NC score	0.037710 (rank : 475)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	409	Target Neighborhood Hits	491	Shared Neighborhood Hits	76
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COFA1_HUMAN
NC score	0.037410 (rank : 476)	θ value	6.88961 (rank : 357)
Query Neighborhood Hits	409	Target Neighborhood Hits	292	Shared Neighborhood Hits	52
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

NCOR1_MOUSE
NC score	0.037401 (rank : 477)	θ value	0.365318 (rank : 168)
Query Neighborhood Hits	409	Target Neighborhood Hits	521	Shared Neighborhood Hits	52
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

COBA1_MOUSE
NC score	0.036832 (rank : 478)	θ value	1.06291 (rank : 207)
Query Neighborhood Hits	409	Target Neighborhood Hits	487	Shared Neighborhood Hits	77
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

IQEC2_HUMAN
NC score	0.036606 (rank : 479)	θ value	1.81305 (rank : 245)
Query Neighborhood Hits	409	Target Neighborhood Hits	403	Shared Neighborhood Hits	69
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

MLL3_MOUSE
NC score	0.036605 (rank : 480)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	409	Target Neighborhood Hits	1399	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

IQEC2_MOUSE
NC score	0.036474 (rank : 481)	θ value	1.81305 (rank : 246)
Query Neighborhood Hits	409	Target Neighborhood Hits	417	Shared Neighborhood Hits	70
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

PDZD2_HUMAN
NC score	0.036374 (rank : 482)	θ value	5.27518 (rank : 339)
Query Neighborhood Hits	409	Target Neighborhood Hits	772	Shared Neighborhood Hits	81
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

HGS_MOUSE
NC score	0.036067 (rank : 483)	θ value	8.99809 (rank : 396)
Query Neighborhood Hits	409	Target Neighborhood Hits	589	Shared Neighborhood Hits	58
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

MINT_HUMAN
NC score	0.035847 (rank : 484)	θ value	6.88961 (rank : 369)
Query Neighborhood Hits	409	Target Neighborhood Hits	1291	Shared Neighborhood Hits	96
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PEX14_MOUSE
NC score	0.035349 (rank : 485)	θ value	3.0926 (rank : 295)
Query Neighborhood Hits	409	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

FUBP1_MOUSE
NC score	0.035189 (rank : 486)	θ value	0.47712 (rank : 181)
Query Neighborhood Hits	409	Target Neighborhood Hits	144	Shared Neighborhood Hits	36
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

COAA1_HUMAN
NC score	0.035124 (rank : 487)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	409	Target Neighborhood Hits	316	Shared Neighborhood Hits	64
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

PP1RA_MOUSE
NC score	0.034965 (rank : 488)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	409	Target Neighborhood Hits	175	Shared Neighborhood Hits	39
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

FUBP1_HUMAN
NC score	0.034837 (rank : 489)	θ value	0.47712 (rank : 180)
Query Neighborhood Hits	409	Target Neighborhood Hits	136	Shared Neighborhood Hits	33
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

CRSP2_HUMAN
NC score	0.034638 (rank : 490)	θ value	6.88961 (rank : 358)
Query Neighborhood Hits	409	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

MILK2_HUMAN
NC score	0.034345 (rank : 491)	θ value	4.03905 (rank : 313)
Query Neighborhood Hits	409	Target Neighborhood Hits	457	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

JADE2_MOUSE
NC score	0.033971 (rank : 492)	θ value	0.813845 (rank : 198)
Query Neighborhood Hits	409	Target Neighborhood Hits	560	Shared Neighborhood Hits	68
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

TARA_HUMAN
NC score	0.033836 (rank : 493)	θ value	2.36792 (rank : 275)
Query Neighborhood Hits	409	Target Neighborhood Hits	1626	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MAP1A_HUMAN
NC score	0.033574 (rank : 494)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	409	Target Neighborhood Hits	1626	Shared Neighborhood Hits	111
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CO2A1_HUMAN
NC score	0.033550 (rank : 495)	θ value	6.88961 (rank : 355)
Query Neighborhood Hits	409	Target Neighborhood Hits	486	Shared Neighborhood Hits	77
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO5A2_HUMAN
NC score	0.033331 (rank : 496)	θ value	8.99809 (rank : 389)
Query Neighborhood Hits	409	Target Neighborhood Hits	760	Shared Neighborhood Hits	87
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO2A1_MOUSE
NC score	0.032893 (rank : 497)	θ value	6.88961 (rank : 356)
Query Neighborhood Hits	409	Target Neighborhood Hits	483	Shared Neighborhood Hits	72
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

SYFB_HUMAN
NC score	0.032697 (rank : 498)	θ value	1.38821 (rank : 237)
Query Neighborhood Hits	409	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSD9, O95708, Q9NZZ6	Gene names	FARSLB, FARSB, FRSB
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

RC3H1_HUMAN
NC score	0.032668 (rank : 499)	θ value	0.0252991 (rank : 117)
Query Neighborhood Hits	409	Target Neighborhood Hits	433	Shared Neighborhood Hits	39
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

NUP53_HUMAN
NC score	0.032063 (rank : 500)	θ value	3.0926 (rank : 294)
Query Neighborhood Hits	409	Target Neighborhood Hits	156	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

LPP_HUMAN
NC score	0.031585 (rank : 501)	θ value	0.62314 (rank : 185)
Query Neighborhood Hits	409	Target Neighborhood Hits	775	Shared Neighborhood Hits	84
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

TULP4_HUMAN
NC score	0.030801 (rank : 502)	θ value	0.365318 (rank : 174)
Query Neighborhood Hits	409	Target Neighborhood Hits	426	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

SOX13_HUMAN
NC score	0.030611 (rank : 503)	θ value	0.62314 (rank : 188)
Query Neighborhood Hits	409	Target Neighborhood Hits	464	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

LYN_HUMAN
NC score	0.029672 (rank : 504)	θ value	8.99809 (rank : 397)
Query Neighborhood Hits	409	Target Neighborhood Hits	1022	Shared Neighborhood Hits	112
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

CND2_HUMAN
NC score	0.029484 (rank : 505)	θ value	1.38821 (rank : 219)
Query Neighborhood Hits	409	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q15003, Q8TB87	Gene names	NCAPH, BRRN, BRRN1, CAPH, KIAA0074
Domain Architecture
Description	Condensin complex subunit 2 (Non-SMC condensin I complex subunit H) (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (XCAP-H homolog).

LYN_MOUSE
NC score	0.029355 (rank : 506)	θ value	6.88961 (rank : 366)
Query Neighborhood Hits	409	Target Neighborhood Hits	1023	Shared Neighborhood Hits	110
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LR37A_HUMAN
NC score	0.028364 (rank : 507)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	409	Target Neighborhood Hits	720	Shared Neighborhood Hits	68
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

STON2_HUMAN
NC score	0.028273 (rank : 508)	θ value	5.27518 (rank : 344)
Query Neighborhood Hits	409	Target Neighborhood Hits	115	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

UBQL3_HUMAN
NC score	0.027953 (rank : 509)	θ value	0.813845 (rank : 205)
Query Neighborhood Hits	409	Target Neighborhood Hits	141	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

AOC3_HUMAN
NC score	0.027908 (rank : 510)	θ value	0.279714 (rank : 161)
Query Neighborhood Hits	409	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q16853, Q45F94	Gene names	AOC3, VAP1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1) (HPAO).

CAC1G_HUMAN
NC score	0.027700 (rank : 511)	θ value	0.163984 (rank : 154)
Query Neighborhood Hits	409	Target Neighborhood Hits	587	Shared Neighborhood Hits	70
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CO4A2_MOUSE
NC score	0.027623 (rank : 512)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	409	Target Neighborhood Hits	492	Shared Neighborhood Hits	66
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

K0329_HUMAN
NC score	0.027537 (rank : 513)	θ value	4.03905 (rank : 311)
Query Neighborhood Hits	409	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

SPR1B_MOUSE
NC score	0.026884 (rank : 514)	θ value	8.99809 (rank : 407)
Query Neighborhood Hits	409	Target Neighborhood Hits	395	Shared Neighborhood Hits	46
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

GR65_HUMAN
NC score	0.026772 (rank : 515)	θ value	5.27518 (rank : 330)
Query Neighborhood Hits	409	Target Neighborhood Hits	148	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

CN037_MOUSE
NC score	0.025693 (rank : 516)	θ value	1.81305 (rank : 242)
Query Neighborhood Hits	409	Target Neighborhood Hits	179	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

ZN414_HUMAN
NC score	0.025509 (rank : 517)	θ value	2.36792 (rank : 279)
Query Neighborhood Hits	409	Target Neighborhood Hits	548	Shared Neighborhood Hits	34
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

CC040_HUMAN
NC score	0.024946 (rank : 518)	θ value	2.36792 (rank : 263)
Query Neighborhood Hits	409	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXB0, Q8TA84	Gene names	C3orf40
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf40 precursor.

RTN1_MOUSE
NC score	0.024506 (rank : 519)	θ value	1.81305 (rank : 250)
Query Neighborhood Hits	409	Target Neighborhood Hits	189	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

NRX2A_HUMAN
NC score	0.024456 (rank : 520)	θ value	5.27518 (rank : 337)
Query Neighborhood Hits	409	Target Neighborhood Hits	614	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

EHMT2_MOUSE
NC score	0.024177 (rank : 521)	θ value	2.36792 (rank : 269)
Query Neighborhood Hits	409	Target Neighborhood Hits	750	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PER3_HUMAN
NC score	0.024159 (rank : 522)	θ value	6.88961 (rank : 375)
Query Neighborhood Hits	409	Target Neighborhood Hits	479	Shared Neighborhood Hits	64
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SYFB_MOUSE
NC score	0.024091 (rank : 523)	θ value	5.27518 (rank : 345)
Query Neighborhood Hits	409	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUA2	Gene names	Farslb, Farsb, Farsl, Frsb
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

AOC3_MOUSE
NC score	0.023874 (rank : 524)	θ value	1.81305 (rank : 239)
Query Neighborhood Hits	409	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	O70423, Q66JM4, Q9R055	Gene names	Aoc3, Vap1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1).

COA2_HUMAN
NC score	0.023627 (rank : 525)	θ value	1.81305 (rank : 243)
Query Neighborhood Hits	409	Target Neighborhood Hits	184	Shared Neighborhood Hits	24
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

RGP1_HUMAN
NC score	0.023580 (rank : 526)	θ value	2.36792 (rank : 271)
Query Neighborhood Hits	409	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

DEN1A_HUMAN
NC score	0.023545 (rank : 527)	θ value	6.88961 (rank : 360)
Query Neighborhood Hits	409	Target Neighborhood Hits	176	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

SOX13_MOUSE
NC score	0.023525 (rank : 528)	θ value	1.81305 (rank : 255)
Query Neighborhood Hits	409	Target Neighborhood Hits	495	Shared Neighborhood Hits	50
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

DLG4_HUMAN
NC score	0.023445 (rank : 529)	θ value	2.36792 (rank : 265)
Query Neighborhood Hits	409	Target Neighborhood Hits	286	Shared Neighborhood Hits	55
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DAB2_HUMAN
NC score	0.023417 (rank : 530)	θ value	0.813845 (rank : 194)
Query Neighborhood Hits	409	Target Neighborhood Hits	197	Shared Neighborhood Hits	27
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DUET_HUMAN
NC score	0.023353 (rank : 531)	θ value	4.03905 (rank : 310)
Query Neighborhood Hits	409	Target Neighborhood Hits	1220	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

AOC2_MOUSE
NC score	0.023335 (rank : 532)	θ value	1.81305 (rank : 238)
Query Neighborhood Hits	409	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q812C9, Q80WP3	Gene names	Aoc2
Domain Architecture
Description	Retina-specific copper amine oxidase precursor (EC 1.4.3.6) (RAO) (Amine oxidase [copper-containing]).

HCN2_HUMAN
NC score	0.023199 (rank : 533)	θ value	6.88961 (rank : 364)
Query Neighborhood Hits	409	Target Neighborhood Hits	369	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

SOX30_MOUSE
NC score	0.022766 (rank : 534)	θ value	5.27518 (rank : 343)
Query Neighborhood Hits	409	Target Neighborhood Hits	374	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

DCP1A_HUMAN
NC score	0.022427 (rank : 535)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	409	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

ZN414_MOUSE
NC score	0.022023 (rank : 536)	θ value	0.47712 (rank : 183)
Query Neighborhood Hits	409	Target Neighborhood Hits	473	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

CEP35_HUMAN
NC score	0.021982 (rank : 537)	θ value	0.47712 (rank : 178)
Query Neighborhood Hits	409	Target Neighborhood Hits	811	Shared Neighborhood Hits	31
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

DLG4_MOUSE
NC score	0.021949 (rank : 538)	θ value	2.36792 (rank : 266)
Query Neighborhood Hits	409	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

EPN2_HUMAN
NC score	0.021857 (rank : 539)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	409	Target Neighborhood Hits	156	Shared Neighborhood Hits	15
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

MATK_MOUSE
NC score	0.021815 (rank : 540)	θ value	1.81305 (rank : 247)
Query Neighborhood Hits	409	Target Neighborhood Hits	952	Shared Neighborhood Hits	62
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

RFIP1_MOUSE
NC score	0.021278 (rank : 541)	θ value	5.27518 (rank : 341)
Query Neighborhood Hits	409	Target Neighborhood Hits	152	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

STIM2_HUMAN
NC score	0.021120 (rank : 542)	θ value	1.81305 (rank : 257)
Query Neighborhood Hits	409	Target Neighborhood Hits	420	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

MATK_HUMAN
NC score	0.021089 (rank : 543)	θ value	4.03905 (rank : 312)
Query Neighborhood Hits	409	Target Neighborhood Hits	954	Shared Neighborhood Hits	57
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

SOX30_HUMAN
NC score	0.020822 (rank : 544)	θ value	1.81305 (rank : 256)
Query Neighborhood Hits	409	Target Neighborhood Hits	305	Shared Neighborhood Hits	31
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

ZDHC1_HUMAN
NC score	0.019648 (rank : 545)	θ value	5.27518 (rank : 348)
Query Neighborhood Hits	409	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

PLXB1_HUMAN
NC score	0.019460 (rank : 546)	θ value	3.0926 (rank : 296)
Query Neighborhood Hits	409	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

CJ012_HUMAN
NC score	0.019090 (rank : 547)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	409	Target Neighborhood Hits	467	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CNTRB_MOUSE
NC score	0.018687 (rank : 548)	θ value	6.88961 (rank : 354)
Query Neighborhood Hits	409	Target Neighborhood Hits	1029	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

MAP2_HUMAN
NC score	0.018675 (rank : 549)	θ value	6.88961 (rank : 367)
Query Neighborhood Hits	409	Target Neighborhood Hits	348	Shared Neighborhood Hits	35
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

K2027_HUMAN
NC score	0.018420 (rank : 550)	θ value	6.88961 (rank : 365)
Query Neighborhood Hits	409	Target Neighborhood Hits	194	Shared Neighborhood Hits	27
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

RNF25_HUMAN
NC score	0.018029 (rank : 551)	θ value	4.03905 (rank : 316)
Query Neighborhood Hits	409	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

DCC_MOUSE
NC score	0.018003 (rank : 552)	θ value	0.0330416 (rank : 119)
Query Neighborhood Hits	409	Target Neighborhood Hits	896	Shared Neighborhood Hits	59
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

IF4B_MOUSE
NC score	0.017990 (rank : 553)	θ value	5.27518 (rank : 335)
Query Neighborhood Hits	409	Target Neighborhood Hits	368	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4B_HUMAN
NC score	0.017706 (rank : 554)	θ value	5.27518 (rank : 334)
Query Neighborhood Hits	409	Target Neighborhood Hits	417	Shared Neighborhood Hits	36
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PTPRN_MOUSE
NC score	0.017688 (rank : 555)	θ value	0.0148317 (rank : 109)
Query Neighborhood Hits	409	Target Neighborhood Hits	240	Shared Neighborhood Hits	33
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

NPBL_MOUSE
NC score	0.017655 (rank : 556)	θ value	8.99809 (rank : 400)
Query Neighborhood Hits	409	Target Neighborhood Hits	1041	Shared Neighborhood Hits	62
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PTC2_HUMAN
NC score	0.017645 (rank : 557)	θ value	1.38821 (rank : 231)
Query Neighborhood Hits	409	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

VGLL4_HUMAN
NC score	0.017409 (rank : 558)	θ value	3.0926 (rank : 300)
Query Neighborhood Hits	409	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q14135, Q7L5V0, Q9BQ78	Gene names	VGLL4, KIAA0121
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 4 (Vgl-4).

SETB1_MOUSE
NC score	0.017337 (rank : 559)	θ value	5.27518 (rank : 342)
Query Neighborhood Hits	409	Target Neighborhood Hits	150	Shared Neighborhood Hits	26
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

INVS_MOUSE
NC score	0.017061 (rank : 560)	θ value	1.81305 (rank : 244)
Query Neighborhood Hits	409	Target Neighborhood Hits	609	Shared Neighborhood Hits	53
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MAGA5_HUMAN
NC score	0.016605 (rank : 561)	θ value	0.62314 (rank : 186)
Query Neighborhood Hits	409	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	P43359	Gene names	MAGEA5, MAGE5
Domain Architecture
Description	Melanoma-associated antigen 5 (MAGE-5 antigen).

SMCA2_HUMAN
NC score	0.016458 (rank : 562)	θ value	3.0926 (rank : 299)
Query Neighborhood Hits	409	Target Neighborhood Hits	503	Shared Neighborhood Hits	58
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

PRR3_HUMAN
NC score	0.016423 (rank : 563)	θ value	8.99809 (rank : 402)
Query Neighborhood Hits	409	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	P79522, Q5RJB5	Gene names	PRR3, CAT56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

EDN3_HUMAN
NC score	0.016362 (rank : 564)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	409	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

DUS2L_HUMAN
NC score	0.015875 (rank : 565)	θ value	8.99809 (rank : 393)
Query Neighborhood Hits	409	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NX74, Q4H4D9	Gene names	DUS2L, DUS2
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 2-like (EC 1.-.-.-) (hDUS2) (Up-regulated in lung cancer) (URLC8).

KCNQ5_HUMAN
NC score	0.015572 (rank : 566)	θ value	0.0736092 (rank : 137)
Query Neighborhood Hits	409	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

ZNFX1_HUMAN
NC score	0.015493 (rank : 567)	θ value	1.06291 (rank : 214)
Query Neighborhood Hits	409	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZN687_HUMAN
NC score	0.015124 (rank : 568)	θ value	0.125558 (rank : 152)
Query Neighborhood Hits	409	Target Neighborhood Hits	1244	Shared Neighborhood Hits	108
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CEP41_HUMAN
NC score	0.015047 (rank : 569)	θ value	8.99809 (rank : 385)
Query Neighborhood Hits	409	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYV8, Q7Z496, Q86TM1, Q8NFU8, Q9H6A3, Q9NPV3	Gene names	TSGA14, CEP41
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specific gene A14 protein).

RBP2_HUMAN
NC score	0.014738 (rank : 570)	θ value	0.279714 (rank : 164)
Query Neighborhood Hits	409	Target Neighborhood Hits	249	Shared Neighborhood Hits	19
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

EHMT2_HUMAN
NC score	0.014714 (rank : 571)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	409	Target Neighborhood Hits	498	Shared Neighborhood Hits	36
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ACK1_MOUSE
NC score	0.014352 (rank : 572)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	409	Target Neighborhood Hits	1080	Shared Neighborhood Hits	106
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

TAF6L_MOUSE
NC score	0.013994 (rank : 573)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	409	Target Neighborhood Hits	146	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

ACK1_HUMAN
NC score	0.013751 (rank : 574)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	409	Target Neighborhood Hits	1140	Shared Neighborhood Hits	101
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

HES7_MOUSE
NC score	0.013470 (rank : 575)	θ value	5.27518 (rank : 332)
Query Neighborhood Hits	409	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

THSD1_MOUSE
NC score	0.013055 (rank : 576)	θ value	2.36792 (rank : 276)
Query Neighborhood Hits	409	Target Neighborhood Hits	153	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CSKP_HUMAN
NC score	0.012019 (rank : 577)	θ value	8.99809 (rank : 391)
Query Neighborhood Hits	409	Target Neighborhood Hits	1022	Shared Neighborhood Hits	84
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

TLE1_MOUSE
NC score	0.011706 (rank : 578)	θ value	2.36792 (rank : 277)
Query Neighborhood Hits	409	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

CSKP_MOUSE
NC score	0.011290 (rank : 579)	θ value	8.99809 (rank : 392)
Query Neighborhood Hits	409	Target Neighborhood Hits	1027	Shared Neighborhood Hits	88
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

MICA1_HUMAN
NC score	0.011077 (rank : 580)	θ value	6.88961 (rank : 368)
Query Neighborhood Hits	409	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

ATOH1_HUMAN
NC score	0.010812 (rank : 581)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	409	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

SEM6B_MOUSE
NC score	0.010412 (rank : 582)	θ value	1.81305 (rank : 253)
Query Neighborhood Hits	409	Target Neighborhood Hits	200	Shared Neighborhood Hits	43
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

RGL2_HUMAN
NC score	0.010208 (rank : 583)	θ value	8.99809 (rank : 404)
Query Neighborhood Hits	409	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

GP157_MOUSE
NC score	0.009843 (rank : 584)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	409	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

TLE1_HUMAN
NC score	0.009618 (rank : 585)	θ value	5.27518 (rank : 347)
Query Neighborhood Hits	409	Target Neighborhood Hits	485	Shared Neighborhood Hits	49
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

CING_HUMAN
NC score	0.009431 (rank : 586)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	409	Target Neighborhood Hits	1275	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

AMOL1_MOUSE
NC score	0.008991 (rank : 587)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	409	Target Neighborhood Hits	445	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

RBM15_HUMAN
NC score	0.008813 (rank : 588)	θ value	8.99809 (rank : 403)
Query Neighborhood Hits	409	Target Neighborhood Hits	309	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

FOXH1_HUMAN
NC score	0.008325 (rank : 589)	θ value	8.99809 (rank : 395)
Query Neighborhood Hits	409	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

MK15_HUMAN
NC score	0.008125 (rank : 590)	θ value	0.00102713 (rank : 72)
Query Neighborhood Hits	409	Target Neighborhood Hits	1038	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

ADA12_MOUSE
NC score	0.007920 (rank : 591)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	409	Target Neighborhood Hits	474	Shared Neighborhood Hits	47
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CAC1B_MOUSE
NC score	0.007445 (rank : 592)	θ value	8.99809 (rank : 384)
Query Neighborhood Hits	409	Target Neighborhood Hits	351	Shared Neighborhood Hits	37
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PANK1_HUMAN
NC score	0.007236 (rank : 593)	θ value	8.99809 (rank : 401)
Query Neighborhood Hits	409	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

TTC16_HUMAN
NC score	0.007153 (rank : 594)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	409	Target Neighborhood Hits	417	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

SLIK3_HUMAN
NC score	0.007135 (rank : 595)	θ value	0.813845 (rank : 203)
Query Neighborhood Hits	409	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	O94933	Gene names	SLITRK3, KIAA0848
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 3 precursor.

SLIK3_MOUSE
NC score	0.007105 (rank : 596)	θ value	0.813845 (rank : 204)
Query Neighborhood Hits	409	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

ADA15_MOUSE
NC score	0.006498 (rank : 597)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	409	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

GLR_MOUSE
NC score	0.006461 (rank : 598)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	409	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

ULK1_MOUSE
NC score	0.006354 (rank : 599)	θ value	0.0961366 (rank : 144)
Query Neighborhood Hits	409	Target Neighborhood Hits	1214	Shared Neighborhood Hits	78
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

GASP1_MOUSE
NC score	0.006303 (rank : 600)	θ value	6.88961 (rank : 363)
Query Neighborhood Hits	409	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

BAI2_HUMAN
NC score	0.005871 (rank : 601)	θ value	8.99809 (rank : 383)
Query Neighborhood Hits	409	Target Neighborhood Hits	332	Shared Neighborhood Hits	21
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

NALP1_HUMAN
NC score	0.005584 (rank : 602)	θ value	4.03905 (rank : 314)
Query Neighborhood Hits	409	Target Neighborhood Hits	138	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

ADA19_HUMAN
NC score	0.005415 (rank : 603)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	409	Target Neighborhood Hits	381	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

DLX4_MOUSE
NC score	0.003413 (rank : 604)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	409	Target Neighborhood Hits	352	Shared Neighborhood Hits	12
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

ISL1_HUMAN
NC score	0.003353 (rank : 605)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	409	Target Neighborhood Hits	421	Shared Neighborhood Hits	13
SwissProt Accessions	P61371, P20663, P47894	Gene names	ISL1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

ISL1_MOUSE
NC score	0.003353 (rank : 606)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	409	Target Neighborhood Hits	421	Shared Neighborhood Hits	13
SwissProt Accessions	P61372, P20663, P47894, Q812D8	Gene names	Isl1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

SP7_MOUSE
NC score	0.001577 (rank : 607)	θ value	0.163984 (rank : 157)
Query Neighborhood Hits	409	Target Neighborhood Hits	756	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

NKX31_MOUSE
NC score	0.001200 (rank : 608)	θ value	3.0926 (rank : 293)
Query Neighborhood Hits	409	Target Neighborhood Hits	379	Shared Neighborhood Hits	15
SwissProt Accessions	P97436, O09087	Gene names	Nkx3-1, Nkx-3.1, Nkx3a
Domain Architecture
Description	Homeobox protein Nkx-3.1.

TAOK2_MOUSE
NC score	0.001052 (rank : 609)	θ value	4.03905 (rank : 319)
Query Neighborhood Hits	409	Target Neighborhood Hits	1373	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

NKX26_MOUSE
NC score	0.000969 (rank : 610)	θ value	3.0926 (rank : 292)
Query Neighborhood Hits	409	Target Neighborhood Hits	343	Shared Neighborhood Hits	11
SwissProt Accessions	P43688	Gene names	Nkx2-6, Nkx-2.6, Nkx2f
Domain Architecture
Description	Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F).

TS1R1_HUMAN
NC score	0.000891 (rank : 611)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	409	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

NUAK1_MOUSE
NC score	-0.000356 (rank : 612)	θ value	0.813845 (rank : 200)
Query Neighborhood Hits	409	Target Neighborhood Hits	881	Shared Neighborhood Hits	20
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

MSX1_HUMAN
NC score	-0.000416 (rank : 613)	θ value	6.88961 (rank : 371)
Query Neighborhood Hits	409	Target Neighborhood Hits	374	Shared Neighborhood Hits	18
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

HXD1_MOUSE
NC score	-0.000489 (rank : 614)	θ value	5.27518 (rank : 333)
Query Neighborhood Hits	409	Target Neighborhood Hits	381	Shared Neighborhood Hits	13
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

SP7_HUMAN
NC score	-0.000552 (rank : 615)	θ value	1.38821 (rank : 235)
Query Neighborhood Hits	409	Target Neighborhood Hits	734	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TDD2	Gene names	SP7, OSX
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix).

GLI1_MOUSE
NC score	-0.003250 (rank : 616)	θ value	0.813845 (rank : 195)
Query Neighborhood Hits	409	Target Neighborhood Hits	785	Shared Neighborhood Hits	28
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

NETR_HUMAN
NC score	-0.003963 (rank : 617)	θ value	6.88961 (rank : 372)
Query Neighborhood Hits	409	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

KLF13_MOUSE
NC score	-0.004059 (rank : 618)	θ value	5.27518 (rank : 336)
Query Neighborhood Hits	409	Target Neighborhood Hits	757	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

ZN263_HUMAN
NC score	-0.005812 (rank : 619)	θ value	2.36792 (rank : 278)
Query Neighborhood Hits	409	Target Neighborhood Hits	795	Shared Neighborhood Hits	17
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).