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Network neighborhood for query Sequence : GMIP_MOUSE

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GMIP_MOUSE
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GMIP_HUMAN
θ value	0 (rank : 1)	NC score	0.984743 (rank : 2)
Query Neighborhood Hits	202	Target Neighborhood Hits	225	Shared Neighborhood Hits	128
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	202	Target Neighborhood Hits	202	Shared Neighborhood Hits	202
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHIN_MOUSE
θ value	2.59387e-31 (rank : 3)	NC score	0.796438 (rank : 10)
Query Neighborhood Hits	202	Target Neighborhood Hits	229	Shared Neighborhood Hits	96
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	3.3877e-31 (rank : 4)	NC score	0.798033 (rank : 8)
Query Neighborhood Hits	202	Target Neighborhood Hits	220	Shared Neighborhood Hits	95
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	3.3877e-31 (rank : 5)	NC score	0.829335 (rank : 4)
Query Neighborhood Hits	202	Target Neighborhood Hits	130	Shared Neighborhood Hits	94
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_HUMAN
θ value	4.42448e-31 (rank : 6)	NC score	0.794931 (rank : 11)
Query Neighborhood Hits	202	Target Neighborhood Hits	227	Shared Neighborhood Hits	95
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

MYO9B_HUMAN
θ value	2.12685e-25 (rank : 7)	NC score	0.436446 (rank : 59)
Query Neighborhood Hits	202	Target Neighborhood Hits	641	Shared Neighborhood Hits	113
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	1.05554e-24 (rank : 8)	NC score	0.440895 (rank : 57)
Query Neighborhood Hits	202	Target Neighborhood Hits	311	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

OPHN1_MOUSE
θ value	1.2077e-20 (rank : 9)	NC score	0.772354 (rank : 17)
Query Neighborhood Hits	202	Target Neighborhood Hits	174	Shared Neighborhood Hits	68
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

TCGAP_MOUSE
θ value	2.69047e-20 (rank : 10)	NC score	0.767334 (rank : 20)
Query Neighborhood Hits	202	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_HUMAN
θ value	5.99374e-20 (rank : 11)	NC score	0.684396 (rank : 39)
Query Neighborhood Hits	202	Target Neighborhood Hits	872	Shared Neighborhood Hits	81
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

OPHN1_HUMAN
θ value	2.27762e-19 (rank : 12)	NC score	0.772941 (rank : 16)
Query Neighborhood Hits	202	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG09_HUMAN
θ value	2.97466e-19 (rank : 13)	NC score	0.834526 (rank : 3)
Query Neighborhood Hits	202	Target Neighborhood Hits	186	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

BCR_HUMAN
θ value	6.62687e-19 (rank : 14)	NC score	0.718338 (rank : 30)
Query Neighborhood Hits	202	Target Neighborhood Hits	204	Shared Neighborhood Hits	74
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

ABR_HUMAN
θ value	1.13037e-18 (rank : 15)	NC score	0.731693 (rank : 27)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	73
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG26_HUMAN
θ value	1.13037e-18 (rank : 16)	NC score	0.729013 (rank : 28)
Query Neighborhood Hits	202	Target Neighborhood Hits	281	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG12_HUMAN
θ value	1.47631e-18 (rank : 17)	NC score	0.798332 (rank : 7)
Query Neighborhood Hits	202	Target Neighborhood Hits	190	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	1.47631e-18 (rank : 18)	NC score	0.797126 (rank : 9)
Query Neighborhood Hits	202	Target Neighborhood Hits	204	Shared Neighborhood Hits	71
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG04_HUMAN
θ value	1.92812e-18 (rank : 19)	NC score	0.717869 (rank : 31)
Query Neighborhood Hits	202	Target Neighborhood Hits	307	Shared Neighborhood Hits	72
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SRGP2_HUMAN
θ value	1.63225e-17 (rank : 20)	NC score	0.705157 (rank : 33)
Query Neighborhood Hits	202	Target Neighborhood Hits	331	Shared Neighborhood Hits	72
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RGAP1_HUMAN
θ value	3.63628e-17 (rank : 21)	NC score	0.810910 (rank : 5)
Query Neighborhood Hits	202	Target Neighborhood Hits	189	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

3BP1_HUMAN
θ value	1.058e-16 (rank : 22)	NC score	0.775944 (rank : 15)
Query Neighborhood Hits	202	Target Neighborhood Hits	376	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GRLF1_HUMAN
θ value	1.38178e-16 (rank : 23)	NC score	0.771649 (rank : 18)
Query Neighborhood Hits	202	Target Neighborhood Hits	167	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

CEND2_HUMAN
θ value	1.80466e-16 (rank : 24)	NC score	0.640868 (rank : 46)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

SRGP2_MOUSE
θ value	1.80466e-16 (rank : 25)	NC score	0.697536 (rank : 34)
Query Neighborhood Hits	202	Target Neighborhood Hits	324	Shared Neighborhood Hits	73
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG06_HUMAN
θ value	3.07829e-16 (rank : 26)	NC score	0.790769 (rank : 12)
Query Neighborhood Hits	202	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	4.02038e-16 (rank : 27)	NC score	0.788944 (rank : 13)
Query Neighborhood Hits	202	Target Neighborhood Hits	105	Shared Neighborhood Hits	63
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SRGP1_HUMAN
θ value	1.16975e-15 (rank : 28)	NC score	0.691063 (rank : 37)
Query Neighborhood Hits	202	Target Neighborhood Hits	390	Shared Neighborhood Hits	88
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
θ value	1.52774e-15 (rank : 29)	NC score	0.685881 (rank : 38)
Query Neighborhood Hits	202	Target Neighborhood Hits	432	Shared Neighborhood Hits	87
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG01_HUMAN
θ value	1.99529e-15 (rank : 30)	NC score	0.767775 (rank : 19)
Query Neighborhood Hits	202	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RGAP1_MOUSE
θ value	2.60593e-15 (rank : 31)	NC score	0.803061 (rank : 6)
Query Neighborhood Hits	202	Target Neighborhood Hits	185	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG25_MOUSE
θ value	3.40345e-15 (rank : 32)	NC score	0.722828 (rank : 29)
Query Neighborhood Hits	202	Target Neighborhood Hits	492	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CE005_MOUSE
θ value	5.8054e-15 (rank : 33)	NC score	0.648697 (rank : 43)
Query Neighborhood Hits	202	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE005_HUMAN
θ value	7.58209e-15 (rank : 34)	NC score	0.651192 (rank : 42)
Query Neighborhood Hits	202	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RHG25_HUMAN
θ value	7.58209e-15 (rank : 35)	NC score	0.695450 (rank : 35)
Query Neighborhood Hits	202	Target Neighborhood Hits	550	Shared Neighborhood Hits	90
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

3BP1_MOUSE
θ value	2.20605e-14 (rank : 36)	NC score	0.788368 (rank : 14)
Query Neighborhood Hits	202	Target Neighborhood Hits	238	Shared Neighborhood Hits	67
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG05_MOUSE
θ value	3.76295e-14 (rank : 37)	NC score	0.740812 (rank : 25)
Query Neighborhood Hits	202	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG08_MOUSE
θ value	1.09485e-13 (rank : 38)	NC score	0.753030 (rank : 23)
Query Neighborhood Hits	202	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
θ value	1.86753e-13 (rank : 39)	NC score	0.746190 (rank : 24)
Query Neighborhood Hits	202	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG05_HUMAN
θ value	2.43908e-13 (rank : 40)	NC score	0.731869 (rank : 26)
Query Neighborhood Hits	202	Target Neighborhood Hits	158	Shared Neighborhood Hits	65
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG18_MOUSE
θ value	2.43908e-13 (rank : 41)	NC score	0.760874 (rank : 22)
Query Neighborhood Hits	202	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

CEND1_HUMAN
θ value	3.18553e-13 (rank : 42)	NC score	0.530594 (rank : 54)
Query Neighborhood Hits	202	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
θ value	4.16044e-13 (rank : 43)	NC score	0.550721 (rank : 53)
Query Neighborhood Hits	202	Target Neighborhood Hits	260	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

RHG18_HUMAN
θ value	4.16044e-13 (rank : 44)	NC score	0.765847 (rank : 21)
Query Neighborhood Hits	202	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

CEND3_MOUSE
θ value	5.43371e-13 (rank : 45)	NC score	0.599900 (rank : 51)
Query Neighborhood Hits	202	Target Neighborhood Hits	228	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
θ value	1.2105e-12 (rank : 46)	NC score	0.588717 (rank : 52)
Query Neighborhood Hits	202	Target Neighborhood Hits	275	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

RHG07_MOUSE
θ value	1.58096e-12 (rank : 47)	NC score	0.673559 (rank : 40)
Query Neighborhood Hits	202	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
θ value	2.69671e-12 (rank : 48)	NC score	0.667694 (rank : 41)
Query Neighborhood Hits	202	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RBP1_HUMAN
θ value	1.02475e-11 (rank : 49)	NC score	0.692628 (rank : 36)
Query Neighborhood Hits	202	Target Neighborhood Hits	521	Shared Neighborhood Hits	97
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_MOUSE
θ value	3.89403e-11 (rank : 50)	NC score	0.709129 (rank : 32)
Query Neighborhood Hits	202	Target Neighborhood Hits	493	Shared Neighborhood Hits	94
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

P85A_MOUSE
θ value	1.133e-10 (rank : 51)	NC score	0.433790 (rank : 60)
Query Neighborhood Hits	202	Target Neighborhood Hits	435	Shared Neighborhood Hits	78
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

STAR8_MOUSE
θ value	1.9326e-10 (rank : 52)	NC score	0.631568 (rank : 47)
Query Neighborhood Hits	202	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
θ value	7.34386e-10 (rank : 53)	NC score	0.622768 (rank : 48)
Query Neighborhood Hits	202	Target Neighborhood Hits	216	Shared Neighborhood Hits	63
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

P85A_HUMAN
θ value	1.25267e-09 (rank : 54)	NC score	0.436661 (rank : 58)
Query Neighborhood Hits	202	Target Neighborhood Hits	479	Shared Neighborhood Hits	81
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

STA13_HUMAN
θ value	4.76016e-09 (rank : 55)	NC score	0.618678 (rank : 49)
Query Neighborhood Hits	202	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
θ value	8.11959e-09 (rank : 56)	NC score	0.609660 (rank : 50)
Query Neighborhood Hits	202	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

TAGAP_HUMAN
θ value	4.92598e-06 (rank : 57)	NC score	0.647249 (rank : 44)
Query Neighborhood Hits	202	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

OCRL_HUMAN
θ value	2.44474e-05 (rank : 58)	NC score	0.352211 (rank : 62)
Query Neighborhood Hits	202	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

K1688_HUMAN
θ value	0.000121331 (rank : 59)	NC score	0.514936 (rank : 56)
Query Neighborhood Hits	202	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

I5P2_HUMAN
θ value	0.00035302 (rank : 60)	NC score	0.353932 (rank : 61)
Query Neighborhood Hits	202	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

P85B_MOUSE
θ value	0.000461057 (rank : 61)	NC score	0.144586 (rank : 65)
Query Neighborhood Hits	202	Target Neighborhood Hits	519	Shared Neighborhood Hits	51
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

TAGAP_MOUSE
θ value	0.000461057 (rank : 62)	NC score	0.644263 (rank : 45)
Query Neighborhood Hits	202	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

K1688_MOUSE
θ value	0.000602161 (rank : 63)	NC score	0.522201 (rank : 55)
Query Neighborhood Hits	202	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

P85B_HUMAN
θ value	0.00228821 (rank : 64)	NC score	0.172651 (rank : 63)
Query Neighborhood Hits	202	Target Neighborhood Hits	543	Shared Neighborhood Hits	54
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GRP3_HUMAN
θ value	0.0431538 (rank : 65)	NC score	0.159915 (rank : 64)
Query Neighborhood Hits	202	Target Neighborhood Hits	131	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

PTN23_MOUSE
θ value	0.0431538 (rank : 66)	NC score	0.027593 (rank : 201)
Query Neighborhood Hits	202	Target Neighborhood Hits	726	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SPTN5_HUMAN
θ value	0.0431538 (rank : 67)	NC score	0.039800 (rank : 148)
Query Neighborhood Hits	202	Target Neighborhood Hits	674	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

TACC2_MOUSE
θ value	0.0736092 (rank : 68)	NC score	0.060321 (rank : 103)
Query Neighborhood Hits	202	Target Neighborhood Hits	774	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

CYLN2_MOUSE
θ value	0.125558 (rank : 69)	NC score	0.038778 (rank : 155)
Query Neighborhood Hits	202	Target Neighborhood Hits	1002	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

TLK2_MOUSE
θ value	0.125558 (rank : 70)	NC score	0.013383 (rank : 240)
Query Neighborhood Hits	202	Target Neighborhood Hits	1088	Shared Neighborhood Hits	56
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

MACF1_MOUSE
θ value	0.163984 (rank : 71)	NC score	0.026108 (rank : 202)
Query Neighborhood Hits	202	Target Neighborhood Hits	1313	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MRCKA_HUMAN
θ value	0.163984 (rank : 72)	NC score	0.044554 (rank : 140)
Query Neighborhood Hits	202	Target Neighborhood Hits	1999	Shared Neighborhood Hits	109
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

PTN23_HUMAN
θ value	0.163984 (rank : 73)	NC score	0.024835 (rank : 205)
Query Neighborhood Hits	202	Target Neighborhood Hits	646	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

STX12_MOUSE
θ value	0.163984 (rank : 74)	NC score	0.033484 (rank : 181)
Query Neighborhood Hits	202	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

VIME_HUMAN
θ value	0.163984 (rank : 75)	NC score	0.020010 (rank : 223)
Query Neighborhood Hits	202	Target Neighborhood Hits	706	Shared Neighborhood Hits	57
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

TACC2_HUMAN
θ value	0.21417 (rank : 76)	NC score	0.056937 (rank : 114)
Query Neighborhood Hits	202	Target Neighborhood Hits	856	Shared Neighborhood Hits	64
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

CCD62_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.038784 (rank : 154)
Query Neighborhood Hits	202	Target Neighborhood Hits	631	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

U2AFM_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.034894 (rank : 173)
Query Neighborhood Hits	202	Target Neighborhood Hits	543	Shared Neighborhood Hits	46
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

VIME_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.020674 (rank : 219)
Query Neighborhood Hits	202	Target Neighborhood Hits	716	Shared Neighborhood Hits	59
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

CCD21_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.033946 (rank : 177)
Query Neighborhood Hits	202	Target Neighborhood Hits	1228	Shared Neighborhood Hits	67
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

LRC49_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.022333 (rank : 211)
Query Neighborhood Hits	202	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IUZ0, Q9NXM6	Gene names	LRRC49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4).

NIN_MOUSE
θ value	0.365318 (rank : 82)	NC score	0.036545 (rank : 166)
Query Neighborhood Hits	202	Target Neighborhood Hits	1376	Shared Neighborhood Hits	71
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PCLO_HUMAN
θ value	0.365318 (rank : 83)	NC score	0.045974 (rank : 138)
Query Neighborhood Hits	202	Target Neighborhood Hits	2046	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
θ value	0.365318 (rank : 84)	NC score	0.039795 (rank : 149)
Query Neighborhood Hits	202	Target Neighborhood Hits	2275	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CENPE_HUMAN
θ value	0.47712 (rank : 85)	NC score	0.029807 (rank : 193)
Query Neighborhood Hits	202	Target Neighborhood Hits	2060	Shared Neighborhood Hits	86
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

NEST_HUMAN
θ value	0.47712 (rank : 86)	NC score	0.029132 (rank : 195)
Query Neighborhood Hits	202	Target Neighborhood Hits	1305	Shared Neighborhood Hits	71
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PERQ1_MOUSE
θ value	0.47712 (rank : 87)	NC score	0.047526 (rank : 137)
Query Neighborhood Hits	202	Target Neighborhood Hits	215	Shared Neighborhood Hits	14
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

UN13B_HUMAN
θ value	0.47712 (rank : 88)	NC score	0.115324 (rank : 66)
Query Neighborhood Hits	202	Target Neighborhood Hits	217	Shared Neighborhood Hits	47
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

KPCT_HUMAN
θ value	0.62314 (rank : 89)	NC score	0.038635 (rank : 157)
Query Neighborhood Hits	202	Target Neighborhood Hits	897	Shared Neighborhood Hits	48
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	0.62314 (rank : 90)	NC score	0.038729 (rank : 156)
Query Neighborhood Hits	202	Target Neighborhood Hits	895	Shared Neighborhood Hits	48
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KSR1_HUMAN
θ value	0.62314 (rank : 91)	NC score	0.021396 (rank : 217)
Query Neighborhood Hits	202	Target Neighborhood Hits	867	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

KSR1_MOUSE
θ value	0.62314 (rank : 92)	NC score	0.022236 (rank : 212)
Query Neighborhood Hits	202	Target Neighborhood Hits	870	Shared Neighborhood Hits	41
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

KSR2_HUMAN
θ value	0.62314 (rank : 93)	NC score	0.022573 (rank : 210)
Query Neighborhood Hits	202	Target Neighborhood Hits	920	Shared Neighborhood Hits	48
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

UN13A_HUMAN
θ value	0.62314 (rank : 94)	NC score	0.113217 (rank : 67)
Query Neighborhood Hits	202	Target Neighborhood Hits	285	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_MOUSE
θ value	0.62314 (rank : 95)	NC score	0.111618 (rank : 68)
Query Neighborhood Hits	202	Target Neighborhood Hits	210	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ENAH_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.033861 (rank : 178)
Query Neighborhood Hits	202	Target Neighborhood Hits	784	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

KPCE_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.039882 (rank : 146)
Query Neighborhood Hits	202	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
θ value	0.813845 (rank : 98)	NC score	0.039845 (rank : 147)
Query Neighborhood Hits	202	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

SRBS1_HUMAN
θ value	0.813845 (rank : 99)	NC score	0.073476 (rank : 84)
Query Neighborhood Hits	202	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

TAB3_MOUSE
θ value	0.813845 (rank : 100)	NC score	0.034304 (rank : 176)
Query Neighborhood Hits	202	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

UBQL4_MOUSE
θ value	0.813845 (rank : 101)	NC score	0.015789 (rank : 235)
Query Neighborhood Hits	202	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

KPCB_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.039177 (rank : 153)
Query Neighborhood Hits	202	Target Neighborhood Hits	1121	Shared Neighborhood Hits	51
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	1.06291 (rank : 103)	NC score	0.039375 (rank : 151)
Query Neighborhood Hits	202	Target Neighborhood Hits	1117	Shared Neighborhood Hits	51
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SPTA2_HUMAN
θ value	1.06291 (rank : 104)	NC score	0.044202 (rank : 141)
Query Neighborhood Hits	202	Target Neighborhood Hits	888	Shared Neighborhood Hits	53
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ENAH_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.036936 (rank : 163)
Query Neighborhood Hits	202	Target Neighborhood Hits	919	Shared Neighborhood Hits	55
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

KPCI_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.031464 (rank : 186)
Query Neighborhood Hits	202	Target Neighborhood Hits	885	Shared Neighborhood Hits	49
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

KPCI_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.031645 (rank : 185)
Query Neighborhood Hits	202	Target Neighborhood Hits	888	Shared Neighborhood Hits	50
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

LRSM1_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.030480 (rank : 189)
Query Neighborhood Hits	202	Target Neighborhood Hits	1078	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PKHG4_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.021404 (rank : 216)
Query Neighborhood Hits	202	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

T53I2_MOUSE
θ value	1.38821 (rank : 110)	NC score	0.023414 (rank : 209)
Query Neighborhood Hits	202	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFU8, Q711P5, Q8CHM4	Gene names	Tp53inp2, Dor, Trp53inp2
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity- regulated protein).

KPCD1_HUMAN
θ value	1.81305 (rank : 111)	NC score	0.036034 (rank : 168)
Query Neighborhood Hits	202	Target Neighborhood Hits	901	Shared Neighborhood Hits	49
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCG_HUMAN
θ value	1.81305 (rank : 112)	NC score	0.037540 (rank : 160)
Query Neighborhood Hits	202	Target Neighborhood Hits	1126	Shared Neighborhood Hits	51
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	1.81305 (rank : 113)	NC score	0.037668 (rank : 159)
Query Neighborhood Hits	202	Target Neighborhood Hits	1123	Shared Neighborhood Hits	51
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MRCKB_MOUSE
θ value	1.81305 (rank : 114)	NC score	0.041579 (rank : 144)
Query Neighborhood Hits	202	Target Neighborhood Hits	2180	Shared Neighborhood Hits	115
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PRR8_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.028281 (rank : 199)
Query Neighborhood Hits	202	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

TRAK1_HUMAN
θ value	1.81305 (rank : 116)	NC score	0.032117 (rank : 184)
Query Neighborhood Hits	202	Target Neighborhood Hits	660	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

XYLT1_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.013330 (rank : 241)
Query Neighborhood Hits	202	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

CCD38_HUMAN
θ value	2.36792 (rank : 118)	NC score	0.020981 (rank : 218)
Query Neighborhood Hits	202	Target Neighborhood Hits	287	Shared Neighborhood Hits	24
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

KPCD_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.039907 (rank : 145)
Query Neighborhood Hits	202	Target Neighborhood Hits	900	Shared Neighborhood Hits	49
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCL_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.037758 (rank : 158)
Query Neighborhood Hits	202	Target Neighborhood Hits	887	Shared Neighborhood Hits	47
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCL_MOUSE
θ value	2.36792 (rank : 121)	NC score	0.037428 (rank : 161)
Query Neighborhood Hits	202	Target Neighborhood Hits	891	Shared Neighborhood Hits	47
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

NCOR2_MOUSE
θ value	2.36792 (rank : 122)	NC score	0.015338 (rank : 236)
Query Neighborhood Hits	202	Target Neighborhood Hits	790	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

ZHX1_MOUSE
θ value	2.36792 (rank : 123)	NC score	0.008491 (rank : 255)
Query Neighborhood Hits	202	Target Neighborhood Hits	334	Shared Neighborhood Hits	3
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

CCHCR_HUMAN
θ value	3.0926 (rank : 124)	NC score	0.028377 (rank : 198)
Query Neighborhood Hits	202	Target Neighborhood Hits	717	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

DMN_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.020405 (rank : 221)
Query Neighborhood Hits	202	Target Neighborhood Hits	690	Shared Neighborhood Hits	50
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

GOGA1_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.030767 (rank : 188)
Query Neighborhood Hits	202	Target Neighborhood Hits	1222	Shared Neighborhood Hits	72
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

KPCD2_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.034330 (rank : 175)
Query Neighborhood Hits	202	Target Neighborhood Hits	910	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

KPCD_MOUSE
θ value	3.0926 (rank : 128)	NC score	0.039755 (rank : 150)
Query Neighborhood Hits	202	Target Neighborhood Hits	888	Shared Neighborhood Hits	49
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

MYCPP_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.011574 (rank : 248)
Query Neighborhood Hits	202	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

OGFR_MOUSE
θ value	3.0926 (rank : 130)	NC score	0.009401 (rank : 253)
Query Neighborhood Hits	202	Target Neighborhood Hits	584	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

QSCN6_HUMAN
θ value	3.0926 (rank : 131)	NC score	0.010797 (rank : 250)
Query Neighborhood Hits	202	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

RIMB1_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.030934 (rank : 187)
Query Neighborhood Hits	202	Target Neighborhood Hits	1376	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SIX5_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.008828 (rank : 254)
Query Neighborhood Hits	202	Target Neighborhood Hits	386	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

TUFT1_MOUSE
θ value	3.0926 (rank : 134)	NC score	0.034384 (rank : 174)
Query Neighborhood Hits	202	Target Neighborhood Hits	732	Shared Neighborhood Hits	58
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

AZI1_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.030411 (rank : 190)
Query Neighborhood Hits	202	Target Neighborhood Hits	1000	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CCD46_MOUSE
θ value	4.03905 (rank : 136)	NC score	0.032539 (rank : 183)
Query Neighborhood Hits	202	Target Neighborhood Hits	1405	Shared Neighborhood Hits	78
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CP250_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.032784 (rank : 182)
Query Neighborhood Hits	202	Target Neighborhood Hits	1805	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DGKK_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.029566 (rank : 194)
Query Neighborhood Hits	202	Target Neighborhood Hits	378	Shared Neighborhood Hits	38
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

ELK1_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.005206 (rank : 259)
Query Neighborhood Hits	202	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

FA47B_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.016502 (rank : 233)
Query Neighborhood Hits	202	Target Neighborhood Hits	431	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GAS7_MOUSE
θ value	4.03905 (rank : 141)	NC score	0.043108 (rank : 142)
Query Neighborhood Hits	202	Target Neighborhood Hits	259	Shared Neighborhood Hits	30
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

KPCD1_MOUSE
θ value	4.03905 (rank : 142)	NC score	0.035375 (rank : 170)
Query Neighborhood Hits	202	Target Neighborhood Hits	891	Shared Neighborhood Hits	49
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

LIPA1_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.029982 (rank : 192)
Query Neighborhood Hits	202	Target Neighborhood Hits	1294	Shared Neighborhood Hits	75
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MRCKB_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.039250 (rank : 152)
Query Neighborhood Hits	202	Target Neighborhood Hits	2239	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SF3B2_HUMAN
θ value	4.03905 (rank : 145)	NC score	0.023729 (rank : 208)
Query Neighborhood Hits	202	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

SLK_MOUSE
θ value	4.03905 (rank : 146)	NC score	0.016163 (rank : 234)
Query Neighborhood Hits	202	Target Neighborhood Hits	1798	Shared Neighborhood Hits	90
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TSSC4_HUMAN
θ value	4.03905 (rank : 147)	NC score	0.017786 (rank : 231)
Query Neighborhood Hits	202	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5U2, Q86VL2, Q9BRS6	Gene names	TSSC4
Domain Architecture	No domain graphic available
Description	Protein TSSC4 (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) (Tumor-suppressing STF cDNA 4 protein).

WNK2_HUMAN
θ value	4.03905 (rank : 148)	NC score	0.011940 (rank : 246)
Query Neighborhood Hits	202	Target Neighborhood Hits	1407	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CING_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.028387 (rank : 197)
Query Neighborhood Hits	202	Target Neighborhood Hits	1432	Shared Neighborhood Hits	74
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

G45IP_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.028100 (rank : 200)
Query Neighborhood Hits	202	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

HOOK3_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.033591 (rank : 180)
Query Neighborhood Hits	202	Target Neighborhood Hits	1070	Shared Neighborhood Hits	67
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

KPCD3_HUMAN
θ value	5.27518 (rank : 152)	NC score	0.036555 (rank : 165)
Query Neighborhood Hits	202	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

KPCD3_MOUSE
θ value	5.27518 (rank : 153)	NC score	0.035856 (rank : 169)
Query Neighborhood Hits	202	Target Neighborhood Hits	901	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

LRRF1_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.019516 (rank : 226)
Query Neighborhood Hits	202	Target Neighborhood Hits	625	Shared Neighborhood Hits	38
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MAP4_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.012312 (rank : 243)
Query Neighborhood Hits	202	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PTCA_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.017814 (rank : 230)
Query Neighborhood Hits	202	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q14761, O00643	Gene names	PTPRCAP, LPAP
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase receptor type C-associated protein (PTPRC-associated protein) (CD45-associated protein) (CD45-AP) (Lymphocyte phosphatase-associated phosphoprotein).

SMOO_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.028435 (rank : 196)
Query Neighborhood Hits	202	Target Neighborhood Hits	391	Shared Neighborhood Hits	18
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SYUG_MOUSE
θ value	5.27518 (rank : 158)	NC score	0.013413 (rank : 239)
Query Neighborhood Hits	202	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0F7	Gene names	Sncg, Persyn
Domain Architecture
Description	Gamma-synuclein (Persyn).

TAB3_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.025814 (rank : 203)
Query Neighborhood Hits	202	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

ZCHC6_HUMAN
θ value	5.27518 (rank : 160)	NC score	0.012099 (rank : 245)
Query Neighborhood Hits	202	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

ZN217_HUMAN
θ value	5.27518 (rank : 161)	NC score	-0.004097 (rank : 264)
Query Neighborhood Hits	202	Target Neighborhood Hits	905	Shared Neighborhood Hits	9
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ATS1_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.000048 (rank : 263)
Query Neighborhood Hits	202	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

BIN1_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.015163 (rank : 237)
Query Neighborhood Hits	202	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CENPF_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.033785 (rank : 179)
Query Neighborhood Hits	202	Target Neighborhood Hits	1932	Shared Neighborhood Hits	87
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DGKQ_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.081564 (rank : 74)
Query Neighborhood Hits	202	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

DHSO_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.008209 (rank : 256)
Query Neighborhood Hits	202	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q00796, Q16682, Q9UMD6	Gene names	SORD
Domain Architecture
Description	Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase).

FYV1_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.017287 (rank : 232)
Query Neighborhood Hits	202	Target Neighborhood Hits	217	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	6.88961 (rank : 168)	NC score	0.017913 (rank : 229)
Query Neighborhood Hits	202	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

IQCB1_MOUSE
θ value	6.88961 (rank : 169)	NC score	0.023819 (rank : 207)
Query Neighborhood Hits	202	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BP00, Q3TNK4, Q8K306	Gene names	Iqcb1, Kiaa0036
Domain Architecture	No domain graphic available
Description	IQ calmodulin-binding motif-containing protein 1.

LRSM1_MOUSE
θ value	6.88961 (rank : 170)	NC score	0.021800 (rank : 215)
Query Neighborhood Hits	202	Target Neighborhood Hits	874	Shared Neighborhood Hits	54
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MINK1_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.010282 (rank : 251)
Query Neighborhood Hits	202	Target Neighborhood Hits	1477	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.010165 (rank : 252)
Query Neighborhood Hits	202	Target Neighborhood Hits	1451	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

RRBP1_MOUSE
θ value	6.88961 (rank : 173)	NC score	0.020640 (rank : 220)
Query Neighborhood Hits	202	Target Neighborhood Hits	1650	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SNX23_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.018699 (rank : 227)
Query Neighborhood Hits	202	Target Neighborhood Hits	944	Shared Neighborhood Hits	63
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

SWP70_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.035230 (rank : 172)
Query Neighborhood Hits	202	Target Neighborhood Hits	973	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

UBP29_MOUSE
θ value	6.88961 (rank : 176)	NC score	0.005748 (rank : 258)
Query Neighborhood Hits	202	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

ANR26_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.022126 (rank : 213)
Query Neighborhood Hits	202	Target Neighborhood Hits	1554	Shared Neighborhood Hits	76
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CENPJ_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.025004 (rank : 204)
Query Neighborhood Hits	202	Target Neighborhood Hits	721	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CS007_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.006652 (rank : 257)
Query Neighborhood Hits	202	Target Neighborhood Hits	464	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DGKI_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.002084 (rank : 261)
Query Neighborhood Hits	202	Target Neighborhood Hits	609	Shared Neighborhood Hits	7
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

GAS7_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.036838 (rank : 164)
Query Neighborhood Hits	202	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GOGA5_MOUSE
θ value	8.99809 (rank : 182)	NC score	0.030139 (rank : 191)
Query Neighborhood Hits	202	Target Neighborhood Hits	1434	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

IFT81_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.024322 (rank : 206)
Query Neighborhood Hits	202	Target Neighborhood Hits	893	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IQCB1_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.022012 (rank : 214)
Query Neighborhood Hits	202	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	Q15051, Q5DKQ7, Q8NI79, Q9BS08	Gene names	IQCB1, KIAA0036, NPHP5
Domain Architecture
Description	IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5).

ITCH_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.011552 (rank : 249)
Query Neighborhood Hits	202	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITCH_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.011768 (rank : 247)
Query Neighborhood Hits	202	Target Neighborhood Hits	127	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

ITSN2_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.054015 (rank : 123)
Query Neighborhood Hits	202	Target Neighborhood Hits	1173	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KPCA_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.037028 (rank : 162)
Query Neighborhood Hits	202	Target Neighborhood Hits	1070	Shared Neighborhood Hits	53
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
θ value	8.99809 (rank : 189)	NC score	0.036279 (rank : 167)
Query Neighborhood Hits	202	Target Neighborhood Hits	1067	Shared Neighborhood Hits	53
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

MACF1_HUMAN
θ value	8.99809 (rank : 190)	NC score	0.020348 (rank : 222)
Query Neighborhood Hits	202	Target Neighborhood Hits	1341	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MYH11_HUMAN
θ value	8.99809 (rank : 191)	NC score	0.044708 (rank : 139)
Query Neighborhood Hits	202	Target Neighborhood Hits	1806	Shared Neighborhood Hits	86
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYO6_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.042115 (rank : 143)
Query Neighborhood Hits	202	Target Neighborhood Hits	727	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

SLK_HUMAN
θ value	8.99809 (rank : 193)	NC score	0.013809 (rank : 238)
Query Neighborhood Hits	202	Target Neighborhood Hits	1775	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SWP70_MOUSE
θ value	8.99809 (rank : 194)	NC score	0.035334 (rank : 171)
Query Neighborhood Hits	202	Target Neighborhood Hits	1097	Shared Neighborhood Hits	70
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TRI36_MOUSE
θ value	8.99809 (rank : 195)	NC score	0.000827 (rank : 262)
Query Neighborhood Hits	202	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

U2AFL_MOUSE
θ value	8.99809 (rank : 196)	NC score	0.019843 (rank : 225)
Query Neighborhood Hits	202	Target Neighborhood Hits	389	Shared Neighborhood Hits	33
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

UACA_HUMAN
θ value	8.99809 (rank : 197)	NC score	0.018059 (rank : 228)
Query Neighborhood Hits	202	Target Neighborhood Hits	1622	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UBP24_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.004786 (rank : 260)
Query Neighborhood Hits	202	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBXD8_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.012227 (rank : 244)
Query Neighborhood Hits	202	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

UBXD8_MOUSE
θ value	8.99809 (rank : 200)	NC score	0.012477 (rank : 242)
Query Neighborhood Hits	202	Target Neighborhood Hits	133	Shared Neighborhood Hits	16
SwissProt Accessions	Q3TDN2, Q3U9W2, Q80TP7, Q80W42	Gene names	Ubxd8, Kiaa0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8.

ZN202_HUMAN
θ value	8.99809 (rank : 201)	NC score	-0.006989 (rank : 265)
Query Neighborhood Hits	202	Target Neighborhood Hits	756	Shared Neighborhood Hits	5
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

ZWINT_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.019971 (rank : 224)
Query Neighborhood Hits	202	Target Neighborhood Hits	497	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

ARFG3_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.050451 (rank : 135)
Query Neighborhood Hits	202	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.050688 (rank : 134)
Query Neighborhood Hits	202	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ATCAY_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.050697 (rank : 133)
Query Neighborhood Hits	202	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATCAY_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.051169 (rank : 131)
Query Neighborhood Hits	202	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

BNIP2_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.053796 (rank : 124)
Query Neighborhood Hits	202	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.053703 (rank : 125)
Query Neighborhood Hits	202	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

CENA1_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.053366 (rank : 126)
Query Neighborhood Hits	202	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.056880 (rank : 115)
Query Neighborhood Hits	202	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.077148 (rank : 77)
Query Neighborhood Hits	202	Target Neighborhood Hits	383	Shared Neighborhood Hits	19
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.082807 (rank : 73)
Query Neighborhood Hits	202	Target Neighborhood Hits	425	Shared Neighborhood Hits	24
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.078118 (rank : 76)
Query Neighborhood Hits	202	Target Neighborhood Hits	395	Shared Neighborhood Hits	18
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CIP4_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.064795 (rank : 94)
Query Neighborhood Hits	202	Target Neighborhood Hits	374	Shared Neighborhood Hits	37
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CRKL_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.051101 (rank : 132)
Query Neighborhood Hits	202	Target Neighborhood Hits	313	Shared Neighborhood Hits	20
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

DAPP1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.063706 (rank : 96)
Query Neighborhood Hits	202	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.066420 (rank : 91)
Query Neighborhood Hits	202	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDEF1_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.055351 (rank : 119)
Query Neighborhood Hits	202	Target Neighborhood Hits	592	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.061021 (rank : 99)
Query Neighborhood Hits	202	Target Neighborhood Hits	599	Shared Neighborhood Hits	30
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.059314 (rank : 107)
Query Neighborhood Hits	202	Target Neighborhood Hits	625	Shared Neighborhood Hits	27
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.054716 (rank : 121)
Query Neighborhood Hits	202	Target Neighborhood Hits	353	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKB_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.051897 (rank : 128)
Query Neighborhood Hits	202	Target Neighborhood Hits	238	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

DGKD_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.065632 (rank : 93)
Query Neighborhood Hits	202	Target Neighborhood Hits	231	Shared Neighborhood Hits	47
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.073156 (rank : 85)
Query Neighborhood Hits	202	Target Neighborhood Hits	255	Shared Neighborhood Hits	49
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DP13A_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.051491 (rank : 129)
Query Neighborhood Hits	202	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

FA13A_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.075590 (rank : 83)
Query Neighborhood Hits	202	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.076337 (rank : 82)
Query Neighborhood Hits	202	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.060249 (rank : 105)
Query Neighborhood Hits	202	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.058926 (rank : 109)
Query Neighborhood Hits	202	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRAP2_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.050078 (rank : 136)
Query Neighborhood Hits	202	Target Neighborhood Hits	304	Shared Neighborhood Hits	20
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.065658 (rank : 92)
Query Neighborhood Hits	202	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.062765 (rank : 98)
Query Neighborhood Hits	202	Target Neighborhood Hits	309	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.063708 (rank : 95)
Query Neighborhood Hits	202	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.063677 (rank : 97)
Query Neighborhood Hits	202	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

ITSN1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.058512 (rank : 110)
Query Neighborhood Hits	202	Target Neighborhood Hits	1757	Shared Neighborhood Hits	105
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.057738 (rank : 112)
Query Neighborhood Hits	202	Target Neighborhood Hits	1669	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.052332 (rank : 127)
Query Neighborhood Hits	202	Target Neighborhood Hits	1371	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MYO10_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.060598 (rank : 101)
Query Neighborhood Hits	202	Target Neighborhood Hits	920	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

NCK2_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.070554 (rank : 87)
Query Neighborhood Hits	202	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

P55G_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.094429 (rank : 69)
Query Neighborhood Hits	202	Target Neighborhood Hits	451	Shared Neighborhood Hits	28
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.093183 (rank : 71)
Query Neighborhood Hits	202	Target Neighborhood Hits	401	Shared Neighborhood Hits	25
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PCTL_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.059858 (rank : 106)
Query Neighborhood Hits	202	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.060539 (rank : 102)
Query Neighborhood Hits	202	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PDZD8_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.093598 (rank : 70)
Query Neighborhood Hits	202	Target Neighborhood Hits	185	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PKHA1_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.056225 (rank : 117)
Query Neighborhood Hits	202	Target Neighborhood Hits	127	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.051262 (rank : 130)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RASF1_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.067948 (rank : 88)
Query Neighborhood Hits	202	Target Neighborhood Hits	62	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF1_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.083192 (rank : 72)
Query Neighborhood Hits	202	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

SMAP1_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.054398 (rank : 122)
Query Neighborhood Hits	202	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.054993 (rank : 120)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.056395 (rank : 116)
Query Neighborhood Hits	202	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.055827 (rank : 118)
Query Neighborhood Hits	202	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SRBS1_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.060297 (rank : 104)
Query Neighborhood Hits	202	Target Neighborhood Hits	409	Shared Neighborhood Hits	28
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAC3_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.076896 (rank : 79)
Query Neighborhood Hits	202	Target Neighborhood Hits	228	Shared Neighborhood Hits	45
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.079122 (rank : 75)
Query Neighborhood Hits	202	Target Neighborhood Hits	232	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.071834 (rank : 86)
Query Neighborhood Hits	202	Target Neighborhood Hits	276	Shared Neighborhood Hits	48
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.076660 (rank : 80)
Query Neighborhood Hits	202	Target Neighborhood Hits	268	Shared Neighborhood Hits	46
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VAV2_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.067853 (rank : 89)
Query Neighborhood Hits	202	Target Neighborhood Hits	453	Shared Neighborhood Hits	54
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.067822 (rank : 90)
Query Neighborhood Hits	202	Target Neighborhood Hits	456	Shared Neighborhood Hits	53
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.077056 (rank : 78)
Query Neighborhood Hits	202	Target Neighborhood Hits	398	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.076390 (rank : 81)
Query Neighborhood Hits	202	Target Neighborhood Hits	404	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.057789 (rank : 111)
Query Neighborhood Hits	202	Target Neighborhood Hits	452	Shared Neighborhood Hits	57
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.059090 (rank : 108)
Query Neighborhood Hits	202	Target Neighborhood Hits	430	Shared Neighborhood Hits	53
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VINEX_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.057144 (rank : 113)
Query Neighborhood Hits	202	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.060723 (rank : 100)
Query Neighborhood Hits	202	Target Neighborhood Hits	286	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

Hits sorted by NC score

GMIP_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	202	Target Neighborhood Hits	202	Shared Neighborhood Hits	202
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.984743 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	202	Target Neighborhood Hits	225	Shared Neighborhood Hits	128
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG09_HUMAN
NC score	0.834526 (rank : 3)	θ value	2.97466e-19 (rank : 13)
Query Neighborhood Hits	202	Target Neighborhood Hits	186	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CHIO_MOUSE
NC score	0.829335 (rank : 4)	θ value	3.3877e-31 (rank : 5)
Query Neighborhood Hits	202	Target Neighborhood Hits	130	Shared Neighborhood Hits	94
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RGAP1_HUMAN
NC score	0.810910 (rank : 5)	θ value	3.63628e-17 (rank : 21)
Query Neighborhood Hits	202	Target Neighborhood Hits	189	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
NC score	0.803061 (rank : 6)	θ value	2.60593e-15 (rank : 31)
Query Neighborhood Hits	202	Target Neighborhood Hits	185	Shared Neighborhood Hits	90
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG12_HUMAN
NC score	0.798332 (rank : 7)	θ value	1.47631e-18 (rank : 17)
Query Neighborhood Hits	202	Target Neighborhood Hits	190	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHIO_HUMAN
NC score	0.798033 (rank : 8)	θ value	3.3877e-31 (rank : 4)
Query Neighborhood Hits	202	Target Neighborhood Hits	220	Shared Neighborhood Hits	95
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG12_MOUSE
NC score	0.797126 (rank : 9)	θ value	1.47631e-18 (rank : 18)
Query Neighborhood Hits	202	Target Neighborhood Hits	204	Shared Neighborhood Hits	71
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHIN_MOUSE
NC score	0.796438 (rank : 10)	θ value	2.59387e-31 (rank : 3)
Query Neighborhood Hits	202	Target Neighborhood Hits	229	Shared Neighborhood Hits	96
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
NC score	0.794931 (rank : 11)	θ value	4.42448e-31 (rank : 6)
Query Neighborhood Hits	202	Target Neighborhood Hits	227	Shared Neighborhood Hits	95
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG06_HUMAN
NC score	0.790769 (rank : 12)	θ value	3.07829e-16 (rank : 26)
Query Neighborhood Hits	202	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.788944 (rank : 13)	θ value	4.02038e-16 (rank : 27)
Query Neighborhood Hits	202	Target Neighborhood Hits	105	Shared Neighborhood Hits	63
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_MOUSE
NC score	0.788368 (rank : 14)	θ value	2.20605e-14 (rank : 36)
Query Neighborhood Hits	202	Target Neighborhood Hits	238	Shared Neighborhood Hits	67
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_HUMAN
NC score	0.775944 (rank : 15)	θ value	1.058e-16 (rank : 22)
Query Neighborhood Hits	202	Target Neighborhood Hits	376	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

OPHN1_HUMAN
NC score	0.772941 (rank : 16)	θ value	2.27762e-19 (rank : 12)
Query Neighborhood Hits	202	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
NC score	0.772354 (rank : 17)	θ value	1.2077e-20 (rank : 9)
Query Neighborhood Hits	202	Target Neighborhood Hits	174	Shared Neighborhood Hits	68
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

GRLF1_HUMAN
NC score	0.771649 (rank : 18)	θ value	1.38178e-16 (rank : 23)
Query Neighborhood Hits	202	Target Neighborhood Hits	167	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG01_HUMAN
NC score	0.767775 (rank : 19)	θ value	1.99529e-15 (rank : 30)
Query Neighborhood Hits	202	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

TCGAP_MOUSE
NC score	0.767334 (rank : 20)	θ value	2.69047e-20 (rank : 10)
Query Neighborhood Hits	202	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG18_HUMAN
NC score	0.765847 (rank : 21)	θ value	4.16044e-13 (rank : 44)
Query Neighborhood Hits	202	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
NC score	0.760874 (rank : 22)	θ value	2.43908e-13 (rank : 41)
Query Neighborhood Hits	202	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_MOUSE
NC score	0.753030 (rank : 23)	θ value	1.09485e-13 (rank : 38)
Query Neighborhood Hits	202	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
NC score	0.746190 (rank : 24)	θ value	1.86753e-13 (rank : 39)
Query Neighborhood Hits	202	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG05_MOUSE
NC score	0.740812 (rank : 25)	θ value	3.76295e-14 (rank : 37)
Query Neighborhood Hits	202	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_HUMAN
NC score	0.731869 (rank : 26)	θ value	2.43908e-13 (rank : 40)
Query Neighborhood Hits	202	Target Neighborhood Hits	158	Shared Neighborhood Hits	65
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

ABR_HUMAN
NC score	0.731693 (rank : 27)	θ value	1.13037e-18 (rank : 15)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	73
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG26_HUMAN
NC score	0.729013 (rank : 28)	θ value	1.13037e-18 (rank : 16)
Query Neighborhood Hits	202	Target Neighborhood Hits	281	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG25_MOUSE
NC score	0.722828 (rank : 29)	θ value	3.40345e-15 (rank : 32)
Query Neighborhood Hits	202	Target Neighborhood Hits	492	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

BCR_HUMAN
NC score	0.718338 (rank : 30)	θ value	6.62687e-19 (rank : 14)
Query Neighborhood Hits	202	Target Neighborhood Hits	204	Shared Neighborhood Hits	74
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG04_HUMAN
NC score	0.717869 (rank : 31)	θ value	1.92812e-18 (rank : 19)
Query Neighborhood Hits	202	Target Neighborhood Hits	307	Shared Neighborhood Hits	72
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RBP1_MOUSE
NC score	0.709129 (rank : 32)	θ value	3.89403e-11 (rank : 50)
Query Neighborhood Hits	202	Target Neighborhood Hits	493	Shared Neighborhood Hits	94
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP2_HUMAN
NC score	0.705157 (rank : 33)	θ value	1.63225e-17 (rank : 20)
Query Neighborhood Hits	202	Target Neighborhood Hits	331	Shared Neighborhood Hits	72
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
NC score	0.697536 (rank : 34)	θ value	1.80466e-16 (rank : 25)
Query Neighborhood Hits	202	Target Neighborhood Hits	324	Shared Neighborhood Hits	73
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG25_HUMAN
NC score	0.695450 (rank : 35)	θ value	7.58209e-15 (rank : 35)
Query Neighborhood Hits	202	Target Neighborhood Hits	550	Shared Neighborhood Hits	90
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RBP1_HUMAN
NC score	0.692628 (rank : 36)	θ value	1.02475e-11 (rank : 49)
Query Neighborhood Hits	202	Target Neighborhood Hits	521	Shared Neighborhood Hits	97
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP1_HUMAN
NC score	0.691063 (rank : 37)	θ value	1.16975e-15 (rank : 28)
Query Neighborhood Hits	202	Target Neighborhood Hits	390	Shared Neighborhood Hits	88
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
NC score	0.685881 (rank : 38)	θ value	1.52774e-15 (rank : 29)
Query Neighborhood Hits	202	Target Neighborhood Hits	432	Shared Neighborhood Hits	87
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

TCGAP_HUMAN
NC score	0.684396 (rank : 39)	θ value	5.99374e-20 (rank : 11)
Query Neighborhood Hits	202	Target Neighborhood Hits	872	Shared Neighborhood Hits	81
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG07_MOUSE
NC score	0.673559 (rank : 40)	θ value	1.58096e-12 (rank : 47)
Query Neighborhood Hits	202	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.667694 (rank : 41)	θ value	2.69671e-12 (rank : 48)
Query Neighborhood Hits	202	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CE005_HUMAN
NC score	0.651192 (rank : 42)	θ value	7.58209e-15 (rank : 34)
Query Neighborhood Hits	202	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.648697 (rank : 43)	θ value	5.8054e-15 (rank : 33)
Query Neighborhood Hits	202	Target Neighborhood Hits	238	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

TAGAP_HUMAN
NC score	0.647249 (rank : 44)	θ value	4.92598e-06 (rank : 57)
Query Neighborhood Hits	202	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
NC score	0.644263 (rank : 45)	θ value	0.000461057 (rank : 62)
Query Neighborhood Hits	202	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CEND2_HUMAN
NC score	0.640868 (rank : 46)	θ value	1.80466e-16 (rank : 24)
Query Neighborhood Hits	202	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

STAR8_MOUSE
NC score	0.631568 (rank : 47)	θ value	1.9326e-10 (rank : 52)
Query Neighborhood Hits	202	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.622768 (rank : 48)	θ value	7.34386e-10 (rank : 53)
Query Neighborhood Hits	202	Target Neighborhood Hits	216	Shared Neighborhood Hits	63
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_HUMAN
NC score	0.618678 (rank : 49)	θ value	4.76016e-09 (rank : 55)
Query Neighborhood Hits	202	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
NC score	0.609660 (rank : 50)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	202	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND3_MOUSE
NC score	0.599900 (rank : 51)	θ value	5.43371e-13 (rank : 45)
Query Neighborhood Hits	202	Target Neighborhood Hits	228	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.588717 (rank : 52)	θ value	1.2105e-12 (rank : 46)
Query Neighborhood Hits	202	Target Neighborhood Hits	275	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND1_MOUSE
NC score	0.550721 (rank : 53)	θ value	4.16044e-13 (rank : 43)
Query Neighborhood Hits	202	Target Neighborhood Hits	260	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.530594 (rank : 54)	θ value	3.18553e-13 (rank : 42)
Query Neighborhood Hits	202	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

K1688_MOUSE
NC score	0.522201 (rank : 55)	θ value	0.000602161 (rank : 63)
Query Neighborhood Hits	202	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.514936 (rank : 56)	θ value	0.000121331 (rank : 59)
Query Neighborhood Hits	202	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MYO9B_MOUSE
NC score	0.440895 (rank : 57)	θ value	1.05554e-24 (rank : 8)
Query Neighborhood Hits	202	Target Neighborhood Hits	311	Shared Neighborhood Hits	103
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.436661 (rank : 58)	θ value	1.25267e-09 (rank : 54)
Query Neighborhood Hits	202	Target Neighborhood Hits	479	Shared Neighborhood Hits	81
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

MYO9B_HUMAN
NC score	0.436446 (rank : 59)	θ value	2.12685e-25 (rank : 7)
Query Neighborhood Hits	202	Target Neighborhood Hits	641	Shared Neighborhood Hits	113
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_MOUSE
NC score	0.433790 (rank : 60)	θ value	1.133e-10 (rank : 51)
Query Neighborhood Hits	202	Target Neighborhood Hits	435	Shared Neighborhood Hits	78
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.353932 (rank : 61)	θ value	0.00035302 (rank : 60)
Query Neighborhood Hits	202	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.352211 (rank : 62)	θ value	2.44474e-05 (rank : 58)
Query Neighborhood Hits	202	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85B_HUMAN
NC score	0.172651 (rank : 63)	θ value	0.00228821 (rank : 64)
Query Neighborhood Hits	202	Target Neighborhood Hits	543	Shared Neighborhood Hits	54
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GRP3_HUMAN
NC score	0.159915 (rank : 64)	θ value	0.0431538 (rank : 65)
Query Neighborhood Hits	202	Target Neighborhood Hits	131	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

P85B_MOUSE
NC score	0.144586 (rank : 65)	θ value	0.000461057 (rank : 61)
Query Neighborhood Hits	202	Target Neighborhood Hits	519	Shared Neighborhood Hits	51
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

UN13B_HUMAN
NC score	0.115324 (rank : 66)	θ value	0.47712 (rank : 88)
Query Neighborhood Hits	202	Target Neighborhood Hits	217	Shared Neighborhood Hits	47
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13A_HUMAN
NC score	0.113217 (rank : 67)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	202	Target Neighborhood Hits	285	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_MOUSE
NC score	0.111618 (rank : 68)	θ value	0.62314 (rank : 95)
Query Neighborhood Hits	202	Target Neighborhood Hits	210	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

P55G_HUMAN
NC score	0.094429 (rank : 69)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	202	Target Neighborhood Hits	451	Shared Neighborhood Hits	28
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PDZD8_HUMAN
NC score	0.093598 (rank : 70)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	202	Target Neighborhood Hits	185	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

P55G_MOUSE
NC score	0.093183 (rank : 71)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	202	Target Neighborhood Hits	401	Shared Neighborhood Hits	25
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

RASF1_MOUSE
NC score	0.083192 (rank : 72)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	202	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

CENB2_HUMAN
NC score	0.082807 (rank : 73)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	202	Target Neighborhood Hits	425	Shared Neighborhood Hits	24
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DGKQ_HUMAN
NC score	0.081564 (rank : 74)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	202	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

STAC3_MOUSE
NC score	0.079122 (rank : 75)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	202	Target Neighborhood Hits	232	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CENB5_HUMAN
NC score	0.078118 (rank : 76)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	202	Target Neighborhood Hits	395	Shared Neighborhood Hits	18
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
NC score	0.077148 (rank : 77)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	202	Target Neighborhood Hits	383	Shared Neighborhood Hits	19
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

VAV3_HUMAN
NC score	0.077056 (rank : 78)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	202	Target Neighborhood Hits	398	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

STAC3_HUMAN
NC score	0.076896 (rank : 79)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	202	Target Neighborhood Hits	228	Shared Neighborhood Hits	45
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_MOUSE
NC score	0.076660 (rank : 80)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	202	Target Neighborhood Hits	268	Shared Neighborhood Hits	46
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VAV3_MOUSE
NC score	0.076390 (rank : 81)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	202	Target Neighborhood Hits	404	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

FA13A_MOUSE
NC score	0.076337 (rank : 82)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	202	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13A_HUMAN
NC score	0.075590 (rank : 83)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	202	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

SRBS1_HUMAN
NC score	0.073476 (rank : 84)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	202	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

DGKH_HUMAN
NC score	0.073156 (rank : 85)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	202	Target Neighborhood Hits	255	Shared Neighborhood Hits	49
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

STAC_HUMAN
NC score	0.071834 (rank : 86)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	202	Target Neighborhood Hits	276	Shared Neighborhood Hits	48
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

NCK2_HUMAN
NC score	0.070554 (rank : 87)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	202	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

RASF1_HUMAN
NC score	0.067948 (rank : 88)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	202	Target Neighborhood Hits	62	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

VAV2_HUMAN
NC score	0.067853 (rank : 89)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	202	Target Neighborhood Hits	453	Shared Neighborhood Hits	54
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
NC score	0.067822 (rank : 90)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	202	Target Neighborhood Hits	456	Shared Neighborhood Hits	53
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

DAPP1_MOUSE
NC score	0.066420 (rank : 91)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	202	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GRAP_HUMAN
NC score	0.065658 (rank : 92)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	202	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

DGKD_HUMAN
NC score	0.065632 (rank : 93)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	202	Target Neighborhood Hits	231	Shared Neighborhood Hits	47
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

CIP4_HUMAN
NC score	0.064795 (rank : 94)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	202	Target Neighborhood Hits	374	Shared Neighborhood Hits	37
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

GRB2_HUMAN
NC score	0.063708 (rank : 95)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	202	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

DAPP1_HUMAN
NC score	0.063706 (rank : 96)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	202	Target Neighborhood Hits	227	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GRB2_MOUSE
NC score	0.063677 (rank : 97)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	202	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRAP_MOUSE
NC score	0.062765 (rank : 98)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	202	Target Neighborhood Hits	309	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

DDEF2_HUMAN
NC score	0.061021 (rank : 99)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	202	Target Neighborhood Hits	599	Shared Neighborhood Hits	30
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

VINEX_MOUSE
NC score	0.060723 (rank : 100)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	202	Target Neighborhood Hits	286	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

MYO10_HUMAN
NC score	0.060598 (rank : 101)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	202	Target Neighborhood Hits	920	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PCTL_MOUSE
NC score	0.060539 (rank : 102)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	202	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

TACC2_MOUSE
NC score	0.060321 (rank : 103)	θ value	0.0736092 (rank : 68)
Query Neighborhood Hits	202	Target Neighborhood Hits	774	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

SRBS1_MOUSE
NC score	0.060297 (rank : 104)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	202	Target Neighborhood Hits	409	Shared Neighborhood Hits	28
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

FA13C_HUMAN
NC score	0.060249 (rank : 105)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	202	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

PCTL_HUMAN
NC score	0.059858 (rank : 106)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	202	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

DDEF2_MOUSE
NC score	0.059314 (rank : 107)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	202	Target Neighborhood Hits	625	Shared Neighborhood Hits	27
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

VAV_MOUSE
NC score	0.059090 (rank : 108)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	202	Target Neighborhood Hits	430	Shared Neighborhood Hits	53
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

FA13C_MOUSE
NC score	0.058926 (rank : 109)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	202	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

ITSN1_HUMAN
NC score	0.058512 (rank : 110)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	202	Target Neighborhood Hits	1757	Shared Neighborhood Hits	105
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

VAV_HUMAN
NC score	0.057789 (rank : 111)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	202	Target Neighborhood Hits	452	Shared Neighborhood Hits	57
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ITSN1_MOUSE
NC score	0.057738 (rank : 112)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	202	Target Neighborhood Hits	1669	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

VINEX_HUMAN
NC score	0.057144 (rank : 113)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	202	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

TACC2_HUMAN
NC score	0.056937 (rank : 114)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	202	Target Neighborhood Hits	856	Shared Neighborhood Hits	64
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

CENA2_HUMAN
NC score	0.056880 (rank : 115)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	202	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

SMP1L_HUMAN
NC score	0.056395 (rank : 116)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	202	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

PKHA1_HUMAN
NC score	0.056225 (rank : 117)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	202	Target Neighborhood Hits	127	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SMP1L_MOUSE
NC score	0.055827 (rank : 118)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	202	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

DDEF1_MOUSE
NC score	0.055351 (rank : 119)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	202	Target Neighborhood Hits	592	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

SMAP1_MOUSE
NC score	0.054993 (rank : 120)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

DDFL1_HUMAN
NC score	0.054716 (rank : 121)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	202	Target Neighborhood Hits	353	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

SMAP1_HUMAN
NC score	0.054398 (rank : 122)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	202	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

ITSN2_HUMAN
NC score	0.054015 (rank : 123)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	202	Target Neighborhood Hits	1173	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

BNIP2_HUMAN
NC score	0.053796 (rank : 124)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	202	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
NC score	0.053703 (rank : 125)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	202	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

CENA1_HUMAN
NC score	0.053366 (rank : 126)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	202	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

ITSN2_MOUSE
NC score	0.052332 (rank : 127)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	202	Target Neighborhood Hits	1371	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

DGKB_HUMAN
NC score	0.051897 (rank : 128)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	202	Target Neighborhood Hits	238	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

DP13A_HUMAN
NC score	0.051491 (rank : 129)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	202	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

PKHA1_MOUSE
NC score	0.051262 (rank : 130)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	202	Target Neighborhood Hits	120	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

ATCAY_MOUSE
NC score	0.051169 (rank : 131)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	202	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

CRKL_HUMAN
NC score	0.051101 (rank : 132)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	202	Target Neighborhood Hits	313	Shared Neighborhood Hits	20
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

ATCAY_HUMAN
NC score	0.050697 (rank : 133)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	202	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ARFG3_MOUSE
NC score	0.050688 (rank : 134)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	202	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_HUMAN
NC score	0.050451 (rank : 135)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	202	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

GRAP2_HUMAN
NC score	0.050078 (rank : 136)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	202	Target Neighborhood Hits	304	Shared Neighborhood Hits	20
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

PERQ1_MOUSE
NC score	0.047526 (rank : 137)	θ value	0.47712 (rank : 87)
Query Neighborhood Hits	202	Target Neighborhood Hits	215	Shared Neighborhood Hits	14
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

PCLO_HUMAN
NC score	0.045974 (rank : 138)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	202	Target Neighborhood Hits	2046	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MYH11_HUMAN
NC score	0.044708 (rank : 139)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	202	Target Neighborhood Hits	1806	Shared Neighborhood Hits	86
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MRCKA_HUMAN
NC score	0.044554 (rank : 140)	θ value	0.163984 (rank : 72)
Query Neighborhood Hits	202	Target Neighborhood Hits	1999	Shared Neighborhood Hits	109
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

SPTA2_HUMAN
NC score	0.044202 (rank : 141)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	202	Target Neighborhood Hits	888	Shared Neighborhood Hits	53
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

GAS7_MOUSE
NC score	0.043108 (rank : 142)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	202	Target Neighborhood Hits	259	Shared Neighborhood Hits	30
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

MYO6_HUMAN
NC score	0.042115 (rank : 143)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	202	Target Neighborhood Hits	727	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MRCKB_MOUSE
NC score	0.041579 (rank : 144)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	202	Target Neighborhood Hits	2180	Shared Neighborhood Hits	115
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

KPCD_HUMAN
NC score	0.039907 (rank : 145)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	202	Target Neighborhood Hits	900	Shared Neighborhood Hits	49
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCE_HUMAN
NC score	0.039882 (rank : 146)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	202	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
NC score	0.039845 (rank : 147)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	202	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

SPTN5_HUMAN
NC score	0.039800 (rank : 148)	θ value	0.0431538 (rank : 67)
Query Neighborhood Hits	202	Target Neighborhood Hits	674	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

PCLO_MOUSE
NC score	0.039795 (rank : 149)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	202	Target Neighborhood Hits	2275	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

KPCD_MOUSE
NC score	0.039755 (rank : 150)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	202	Target Neighborhood Hits	888	Shared Neighborhood Hits	49
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCB_MOUSE
NC score	0.039375 (rank : 151)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	202	Target Neighborhood Hits	1117	Shared Neighborhood Hits	51
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

MRCKB_HUMAN
NC score	0.039250 (rank : 152)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	202	Target Neighborhood Hits	2239	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

KPCB_HUMAN
NC score	0.039177 (rank : 153)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	202	Target Neighborhood Hits	1121	Shared Neighborhood Hits	51
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

CCD62_HUMAN
NC score	0.038784 (rank : 154)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	202	Target Neighborhood Hits	631	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CYLN2_MOUSE
NC score	0.038778 (rank : 155)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	202	Target Neighborhood Hits	1002	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

KPCT_MOUSE
NC score	0.038729 (rank : 156)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	202	Target Neighborhood Hits	895	Shared Neighborhood Hits	48
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_HUMAN
NC score	0.038635 (rank : 157)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	202	Target Neighborhood Hits	897	Shared Neighborhood Hits	48
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCL_HUMAN
NC score	0.037758 (rank : 158)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	202	Target Neighborhood Hits	887	Shared Neighborhood Hits	47
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCG_MOUSE
NC score	0.037668 (rank : 159)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	202	Target Neighborhood Hits	1123	Shared Neighborhood Hits	51
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
NC score	0.037540 (rank : 160)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	202	Target Neighborhood Hits	1126	Shared Neighborhood Hits	51
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCL_MOUSE
NC score	0.037428 (rank : 161)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	202	Target Neighborhood Hits	891	Shared Neighborhood Hits	47
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCA_HUMAN
NC score	0.037028 (rank : 162)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	202	Target Neighborhood Hits	1070	Shared Neighborhood Hits	53
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

ENAH_MOUSE
NC score	0.036936 (rank : 163)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	202	Target Neighborhood Hits	919	Shared Neighborhood Hits	55
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GAS7_HUMAN
NC score	0.036838 (rank : 164)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	202	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

KPCD3_HUMAN
NC score	0.036555 (rank : 165)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	202	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

NIN_MOUSE
NC score	0.036545 (rank : 166)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	202	Target Neighborhood Hits	1376	Shared Neighborhood Hits	71
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

KPCA_MOUSE
NC score	0.036279 (rank : 167)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	202	Target Neighborhood Hits	1067	Shared Neighborhood Hits	53
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCD1_HUMAN
NC score	0.036034 (rank : 168)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	202	Target Neighborhood Hits	901	Shared Neighborhood Hits	49
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD3_MOUSE
NC score	0.035856 (rank : 169)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	202	Target Neighborhood Hits	901	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

KPCD1_MOUSE
NC score	0.035375 (rank : 170)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	202	Target Neighborhood Hits	891	Shared Neighborhood Hits	49
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

SWP70_MOUSE
NC score	0.035334 (rank : 171)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	202	Target Neighborhood Hits	1097	Shared Neighborhood Hits	70
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_HUMAN
NC score	0.035230 (rank : 172)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	202	Target Neighborhood Hits	973	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

U2AFM_MOUSE
NC score	0.034894 (rank : 173)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	202	Target Neighborhood Hits	543	Shared Neighborhood Hits	46
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

TUFT1_MOUSE
NC score	0.034384 (rank : 174)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	202	Target Neighborhood Hits	732	Shared Neighborhood Hits	58
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

KPCD2_HUMAN
NC score	0.034330 (rank : 175)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	202	Target Neighborhood Hits	910	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

TAB3_MOUSE
NC score	0.034304 (rank : 176)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	202	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

CCD21_HUMAN
NC score	0.033946 (rank : 177)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	202	Target Neighborhood Hits	1228	Shared Neighborhood Hits	67
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

ENAH_HUMAN
NC score	0.033861 (rank : 178)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	202	Target Neighborhood Hits	784	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

CENPF_HUMAN
NC score	0.033785 (rank : 179)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	202	Target Neighborhood Hits	1932	Shared Neighborhood Hits	87
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

HOOK3_HUMAN
NC score	0.033591 (rank : 180)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	202	Target Neighborhood Hits	1070	Shared Neighborhood Hits	67
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

STX12_MOUSE
NC score	0.033484 (rank : 181)	θ value	0.163984 (rank : 74)
Query Neighborhood Hits	202	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

CP250_HUMAN
NC score	0.032784 (rank : 182)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	202	Target Neighborhood Hits	1805	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CCD46_MOUSE
NC score	0.032539 (rank : 183)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	202	Target Neighborhood Hits	1405	Shared Neighborhood Hits	78
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

TRAK1_HUMAN
NC score	0.032117 (rank : 184)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	202	Target Neighborhood Hits	660	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

KPCI_MOUSE
NC score	0.031645 (rank : 185)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	202	Target Neighborhood Hits	888	Shared Neighborhood Hits	50
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

KPCI_HUMAN
NC score	0.031464 (rank : 186)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	202	Target Neighborhood Hits	885	Shared Neighborhood Hits	49
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

RIMB1_MOUSE
NC score	0.030934 (rank : 187)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	202	Target Neighborhood Hits	1376	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

GOGA1_HUMAN
NC score	0.030767 (rank : 188)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	202	Target Neighborhood Hits	1222	Shared Neighborhood Hits	72
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

LRSM1_HUMAN
NC score	0.030480 (rank : 189)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	202	Target Neighborhood Hits	1078	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

AZI1_HUMAN
NC score	0.030411 (rank : 190)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	202	Target Neighborhood Hits	1000	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

GOGA5_MOUSE
NC score	0.030139 (rank : 191)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	202	Target Neighborhood Hits	1434	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

LIPA1_HUMAN
NC score	0.029982 (rank : 192)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	202	Target Neighborhood Hits	1294	Shared Neighborhood Hits	75
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

CENPE_HUMAN
NC score	0.029807 (rank : 193)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	202	Target Neighborhood Hits	2060	Shared Neighborhood Hits	86
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DGKK_HUMAN
NC score	0.029566 (rank : 194)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	202	Target Neighborhood Hits	378	Shared Neighborhood Hits	38
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

NEST_HUMAN
NC score	0.029132 (rank : 195)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	202	Target Neighborhood Hits	1305	Shared Neighborhood Hits	71
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

SMOO_HUMAN
NC score	0.028435 (rank : 196)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	202	Target Neighborhood Hits	391	Shared Neighborhood Hits	18
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CING_MOUSE
NC score	0.028387 (rank : 197)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	202	Target Neighborhood Hits	1432	Shared Neighborhood Hits	74
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CCHCR_HUMAN
NC score	0.028377 (rank : 198)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	202	Target Neighborhood Hits	717	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

PRR8_HUMAN
NC score	0.028281 (rank : 199)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	202	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

G45IP_MOUSE
NC score	0.028100 (rank : 200)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	202	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

PTN23_MOUSE
NC score	0.027593 (rank : 201)	θ value	0.0431538 (rank : 66)
Query Neighborhood Hits	202	Target Neighborhood Hits	726	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MACF1_MOUSE
NC score	0.026108 (rank : 202)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	202	Target Neighborhood Hits	1313	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

TAB3_HUMAN
NC score	0.025814 (rank : 203)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	202	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

CENPJ_HUMAN
NC score	0.025004 (rank : 204)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	202	Target Neighborhood Hits	721	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

PTN23_HUMAN
NC score	0.024835 (rank : 205)	θ value	0.163984 (rank : 73)
Query Neighborhood Hits	202	Target Neighborhood Hits	646	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

IFT81_HUMAN
NC score	0.024322 (rank : 206)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	202	Target Neighborhood Hits	893	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IQCB1_MOUSE
NC score	0.023819 (rank : 207)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	202	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BP00, Q3TNK4, Q8K306	Gene names	Iqcb1, Kiaa0036
Domain Architecture	No domain graphic available
Description	IQ calmodulin-binding motif-containing protein 1.

SF3B2_HUMAN
NC score	0.023729 (rank : 208)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	202	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

T53I2_MOUSE
NC score	0.023414 (rank : 209)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	202	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFU8, Q711P5, Q8CHM4	Gene names	Tp53inp2, Dor, Trp53inp2
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity- regulated protein).

KSR2_HUMAN
NC score	0.022573 (rank : 210)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	202	Target Neighborhood Hits	920	Shared Neighborhood Hits	48
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

LRC49_HUMAN
NC score	0.022333 (rank : 211)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	202	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IUZ0, Q9NXM6	Gene names	LRRC49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4).

KSR1_MOUSE
NC score	0.022236 (rank : 212)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	202	Target Neighborhood Hits	870	Shared Neighborhood Hits	41
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

ANR26_MOUSE
NC score	0.022126 (rank : 213)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	202	Target Neighborhood Hits	1554	Shared Neighborhood Hits	76
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

IQCB1_HUMAN
NC score	0.022012 (rank : 214)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	202	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	Q15051, Q5DKQ7, Q8NI79, Q9BS08	Gene names	IQCB1, KIAA0036, NPHP5
Domain Architecture
Description	IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5).

LRSM1_MOUSE
NC score	0.021800 (rank : 215)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	202	Target Neighborhood Hits	874	Shared Neighborhood Hits	54
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

PKHG4_HUMAN
NC score	0.021404 (rank : 216)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	202	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

KSR1_HUMAN
NC score	0.021396 (rank : 217)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	202	Target Neighborhood Hits	867	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

CCD38_HUMAN
NC score	0.020981 (rank : 218)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	202	Target Neighborhood Hits	287	Shared Neighborhood Hits	24
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

VIME_MOUSE
NC score	0.020674 (rank : 219)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	202	Target Neighborhood Hits	716	Shared Neighborhood Hits	59
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

RRBP1_MOUSE
NC score	0.020640 (rank : 220)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	202	Target Neighborhood Hits	1650	Shared Neighborhood Hits	69
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

DMN_HUMAN
NC score	0.020405 (rank : 221)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	202	Target Neighborhood Hits	690	Shared Neighborhood Hits	50
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

MACF1_HUMAN
NC score	0.020348 (rank : 222)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	202	Target Neighborhood Hits	1341	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

VIME_HUMAN
NC score	0.020010 (rank : 223)	θ value	0.163984 (rank : 75)
Query Neighborhood Hits	202	Target Neighborhood Hits	706	Shared Neighborhood Hits	57
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

ZWINT_MOUSE
NC score	0.019971 (rank : 224)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	202	Target Neighborhood Hits	497	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

U2AFL_MOUSE
NC score	0.019843 (rank : 225)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	202	Target Neighborhood Hits	389	Shared Neighborhood Hits	33
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

LRRF1_HUMAN
NC score	0.019516 (rank : 226)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	202	Target Neighborhood Hits	625	Shared Neighborhood Hits	38
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

SNX23_HUMAN
NC score	0.018699 (rank : 227)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	202	Target Neighborhood Hits	944	Shared Neighborhood Hits	63
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

UACA_HUMAN
NC score	0.018059 (rank : 228)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	202	Target Neighborhood Hits	1622	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

FYV1_MOUSE
NC score	0.017913 (rank : 229)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	202	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

PTCA_HUMAN
NC score	0.017814 (rank : 230)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	202	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q14761, O00643	Gene names	PTPRCAP, LPAP
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase receptor type C-associated protein (PTPRC-associated protein) (CD45-associated protein) (CD45-AP) (Lymphocyte phosphatase-associated phosphoprotein).

TSSC4_HUMAN
NC score	0.017786 (rank : 231)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	202	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5U2, Q86VL2, Q9BRS6	Gene names	TSSC4
Domain Architecture	No domain graphic available
Description	Protein TSSC4 (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) (Tumor-suppressing STF cDNA 4 protein).

FYV1_HUMAN
NC score	0.017287 (rank : 232)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	202	Target Neighborhood Hits	217	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FA47B_HUMAN
NC score	0.016502 (rank : 233)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	202	Target Neighborhood Hits	431	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SLK_MOUSE
NC score	0.016163 (rank : 234)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	202	Target Neighborhood Hits	1798	Shared Neighborhood Hits	90
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

UBQL4_MOUSE
NC score	0.015789 (rank : 235)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	202	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

NCOR2_MOUSE
NC score	0.015338 (rank : 236)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	202	Target Neighborhood Hits	790	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

BIN1_MOUSE
NC score	0.015163 (rank : 237)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	202	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

SLK_HUMAN
NC score	0.013809 (rank : 238)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	202	Target Neighborhood Hits	1775	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SYUG_MOUSE
NC score	0.013413 (rank : 239)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	202	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0F7	Gene names	Sncg, Persyn
Domain Architecture
Description	Gamma-synuclein (Persyn).

TLK2_MOUSE
NC score	0.013383 (rank : 240)	θ value	0.125558 (rank : 70)
Query Neighborhood Hits	202	Target Neighborhood Hits	1088	Shared Neighborhood Hits	56
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

XYLT1_HUMAN
NC score	0.013330 (rank : 241)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	202	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

UBXD8_MOUSE
NC score	0.012477 (rank : 242)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	202	Target Neighborhood Hits	133	Shared Neighborhood Hits	16
SwissProt Accessions	Q3TDN2, Q3U9W2, Q80TP7, Q80W42	Gene names	Ubxd8, Kiaa0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8.

MAP4_MOUSE
NC score	0.012312 (rank : 243)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	202	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

UBXD8_HUMAN
NC score	0.012227 (rank : 244)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	202	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	Q96CS3, O94963, Q8IUF2, Q9BRP2, Q9BVM7	Gene names	UBXD8, ETEA, KIAA0887
Domain Architecture	No domain graphic available
Description	UBX domain-containing protein 8 (Protein ETEA).

ZCHC6_HUMAN
NC score	0.012099 (rank : 245)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	202	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

WNK2_HUMAN
NC score	0.011940 (rank : 246)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	202	Target Neighborhood Hits	1407	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ITCH_MOUSE
NC score	0.011768 (rank : 247)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	202	Target Neighborhood Hits	127	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

MYCPP_HUMAN
NC score	0.011574 (rank : 248)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	202	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z401, Q14655, Q86T77, Q8IVX2, Q8NB93	Gene names	MYCPBP, IRLB
Domain Architecture	No domain graphic available
Description	C-myc promoter-binding protein.

ITCH_HUMAN
NC score	0.011552 (rank : 249)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	202	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

QSCN6_HUMAN
NC score	0.010797 (rank : 250)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	202	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

MINK1_HUMAN
NC score	0.010282 (rank : 251)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	202	Target Neighborhood Hits	1477	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
NC score	0.010165 (rank : 252)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	202	Target Neighborhood Hits	1451	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

OGFR_MOUSE
NC score	0.009401 (rank : 253)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	202	Target Neighborhood Hits	584	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SIX5_HUMAN
NC score	0.008828 (rank : 254)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	202	Target Neighborhood Hits	386	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N196	Gene names	SIX5, DMAHP
Domain Architecture	No domain graphic available
Description	Homeobox protein SIX5 (DM locus-associated homeodomain protein).

ZHX1_MOUSE
NC score	0.008491 (rank : 255)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	202	Target Neighborhood Hits	334	Shared Neighborhood Hits	3
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

DHSO_HUMAN
NC score	0.008209 (rank : 256)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	202	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q00796, Q16682, Q9UMD6	Gene names	SORD
Domain Architecture
Description	Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase).

CS007_MOUSE
NC score	0.006652 (rank : 257)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	202	Target Neighborhood Hits	464	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

UBP29_MOUSE
NC score	0.005748 (rank : 258)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	202	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

ELK1_HUMAN
NC score	0.005206 (rank : 259)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	202	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

UBP24_HUMAN
NC score	0.004786 (rank : 260)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	202	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

DGKI_HUMAN
NC score	0.002084 (rank : 261)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	202	Target Neighborhood Hits	609	Shared Neighborhood Hits	7
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

TRI36_MOUSE
NC score	0.000827 (rank : 262)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	202	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

ATS1_MOUSE
NC score	0.000048 (rank : 263)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	202	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ZN217_HUMAN
NC score	-0.004097 (rank : 264)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	202	Target Neighborhood Hits	905	Shared Neighborhood Hits	9
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ZN202_HUMAN
NC score	-0.006989 (rank : 265)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	202	Target Neighborhood Hits	756	Shared Neighborhood Hits	5
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.