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Network neighborhood for query Sequence : RHG08_MOUSE

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RHG08_MOUSE
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RHG08_HUMAN
θ value	0 (rank : 1)	NC score	0.993191 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG01_HUMAN
θ value	4.1775e-114 (rank : 3)	NC score	0.983910 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

BNIP2_MOUSE
θ value	1.5773e-20 (rank : 4)	NC score	0.470895 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_HUMAN
θ value	4.58923e-20 (rank : 5)	NC score	0.470983 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

RHG25_HUMAN
θ value	3.88503e-19 (rank : 6)	NC score	0.701044 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	550	Shared Neighborhood Hits	60
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

3BP1_HUMAN
θ value	6.62687e-19 (rank : 7)	NC score	0.764716 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	376	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG25_MOUSE
θ value	1.92812e-18 (rank : 8)	NC score	0.719093 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	492	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

ATCAY_HUMAN
θ value	9.56915e-18 (rank : 9)	NC score	0.460451 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATCAY_MOUSE
θ value	9.56915e-18 (rank : 10)	NC score	0.462112 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

BNIPL_HUMAN
θ value	2.13179e-17 (rank : 11)	NC score	0.454863 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

3BP1_MOUSE
θ value	1.058e-16 (rank : 12)	NC score	0.786485 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	238	Shared Neighborhood Hits	62
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BNIPL_MOUSE
θ value	1.38178e-16 (rank : 13)	NC score	0.457483 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

GMIP_HUMAN
θ value	1.16975e-15 (rank : 14)	NC score	0.755149 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG06_MOUSE
θ value	1.16975e-15 (rank : 15)	NC score	0.771257 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG12_MOUSE
θ value	1.52774e-15 (rank : 16)	NC score	0.751789 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

TAGAP_MOUSE
θ value	1.52774e-15 (rank : 17)	NC score	0.737396 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_HUMAN
θ value	1.99529e-15 (rank : 18)	NC score	0.737560 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG06_HUMAN
θ value	2.60593e-15 (rank : 19)	NC score	0.772893 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CHIO_MOUSE
θ value	3.40345e-15 (rank : 20)	NC score	0.714975 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

FNBP2_HUMAN
θ value	3.40345e-15 (rank : 21)	NC score	0.665768 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	432	Shared Neighborhood Hits	62
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

SRGP2_HUMAN
θ value	3.40345e-15 (rank : 22)	NC score	0.684053 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

CHIO_HUMAN
θ value	4.44505e-15 (rank : 23)	NC score	0.683886 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	220	Shared Neighborhood Hits	61
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

SRGP1_HUMAN
θ value	5.8054e-15 (rank : 24)	NC score	0.665941 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	390	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

CHIN_MOUSE
θ value	9.90251e-15 (rank : 25)	NC score	0.685244 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG09_HUMAN
θ value	1.29331e-14 (rank : 26)	NC score	0.774057 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_HUMAN
θ value	1.29331e-14 (rank : 27)	NC score	0.750468 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	190	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHIN_HUMAN
θ value	1.68911e-14 (rank : 28)	NC score	0.681360 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

SRGP2_MOUSE
θ value	3.76295e-14 (rank : 29)	NC score	0.676586 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	324	Shared Neighborhood Hits	62
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

ABR_HUMAN
θ value	6.41864e-14 (rank : 30)	NC score	0.673291 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

GMIP_MOUSE
θ value	1.09485e-13 (rank : 31)	NC score	0.753030 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	202	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG04_HUMAN
θ value	1.86753e-13 (rank : 32)	NC score	0.683229 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RBP1_HUMAN
θ value	4.16044e-13 (rank : 33)	NC score	0.655395 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	521	Shared Neighborhood Hits	60
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

BCR_HUMAN
θ value	7.09661e-13 (rank : 34)	NC score	0.655575 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

MYO9B_MOUSE
θ value	9.26847e-13 (rank : 35)	NC score	0.389039 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	311	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RBP1_MOUSE
θ value	9.26847e-13 (rank : 36)	NC score	0.671868 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	493	Shared Neighborhood Hits	60
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG05_MOUSE
θ value	1.58096e-12 (rank : 37)	NC score	0.695213 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

TCGAP_HUMAN
θ value	1.58096e-12 (rank : 38)	NC score	0.624177 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	872	Shared Neighborhood Hits	62
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RGAP1_MOUSE
θ value	2.69671e-12 (rank : 39)	NC score	0.735788 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	185	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

MYO9B_HUMAN
θ value	4.59992e-12 (rank : 40)	NC score	0.382835 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	641	Shared Neighborhood Hits	62
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TCGAP_MOUSE
θ value	4.59992e-12 (rank : 41)	NC score	0.703292 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	409	Shared Neighborhood Hits	62
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CE005_MOUSE
θ value	7.84624e-12 (rank : 42)	NC score	0.621571 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	238	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE005_HUMAN
θ value	1.33837e-11 (rank : 43)	NC score	0.623579 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

GRLF1_HUMAN
θ value	1.33837e-11 (rank : 44)	NC score	0.723594 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG18_MOUSE
θ value	1.33837e-11 (rank : 45)	NC score	0.728081 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

OPHN1_MOUSE
θ value	1.74796e-11 (rank : 46)	NC score	0.696699 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
θ value	3.89403e-11 (rank : 47)	NC score	0.697704 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG26_HUMAN
θ value	1.133e-10 (rank : 48)	NC score	0.652243 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	281	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RGAP1_HUMAN
θ value	1.47974e-10 (rank : 49)	NC score	0.733985 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG05_HUMAN
θ value	1.47974e-10 (rank : 50)	NC score	0.680950 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	158	Shared Neighborhood Hits	62
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG18_HUMAN
θ value	1.47974e-10 (rank : 51)	NC score	0.724505 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

CEND2_HUMAN
θ value	1.9326e-10 (rank : 52)	NC score	0.556336 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

K1688_MOUSE
θ value	4.30538e-10 (rank : 53)	NC score	0.590182 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
θ value	5.62301e-10 (rank : 54)	NC score	0.576728 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	217	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

RHG07_MOUSE
θ value	1.25267e-09 (rank : 55)	NC score	0.637405 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
θ value	8.11959e-09 (rank : 56)	NC score	0.632113 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

STA13_HUMAN
θ value	8.11959e-09 (rank : 57)	NC score	0.589957 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

I5P2_HUMAN
θ value	3.08544e-08 (rank : 58)	NC score	0.392125 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
θ value	5.26297e-08 (rank : 59)	NC score	0.381499 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

STA13_MOUSE
θ value	8.97725e-08 (rank : 60)	NC score	0.579538 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

P85A_HUMAN
θ value	1.29631e-06 (rank : 61)	NC score	0.365595 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	479	Shared Neighborhood Hits	58
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

STAR8_MOUSE
θ value	1.29631e-06 (rank : 62)	NC score	0.588802 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

P85A_MOUSE
θ value	3.77169e-06 (rank : 63)	NC score	0.355955 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	435	Shared Neighborhood Hits	58
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

STAR8_HUMAN
θ value	4.92598e-06 (rank : 64)	NC score	0.579198 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	216	Shared Neighborhood Hits	59
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND1_MOUSE
θ value	3.19293e-05 (rank : 65)	NC score	0.455219 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	260	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
θ value	0.000158464 (rank : 66)	NC score	0.434586 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	284	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND3_HUMAN
θ value	0.00102713 (rank : 67)	NC score	0.485125 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	275	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
θ value	0.00175202 (rank : 68)	NC score	0.494323 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	228	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

NF1_HUMAN
θ value	0.0193708 (rank : 69)	NC score	0.052934 (rank : 82)
Query Neighborhood Hits	73	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P21359, O00662, Q14284, Q14930, Q9UMK3	Gene names	NF1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1) [Contains: Neurofibromin truncated].

NF1_MOUSE
θ value	0.0252991 (rank : 70)	NC score	0.052376 (rank : 83)
Query Neighborhood Hits	73	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q04690, Q61956, Q61957	Gene names	Nf1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1).

S14L2_HUMAN
θ value	0.0330416 (rank : 71)	NC score	0.050304 (rank : 87)
Query Neighborhood Hits	73	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O76054, Q9ULN4	Gene names	SEC14L2, KIAA1186
Domain Architecture
Description	SEC14-like protein 2 (Alpha-tocopherol-associated protein) (TAP) (hTAP) (Supernatant protein factor) (SPF) (Squalene transfer protein).

S14L2_MOUSE
θ value	0.0431538 (rank : 72)	NC score	0.049748 (rank : 90)
Query Neighborhood Hits	73	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q99J08	Gene names	Sec14l2
Domain Architecture
Description	SEC14-like protein 2 (Alpha-tocopherol-associated protein) (TAP).

AFAD_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.009196 (rank : 91)
Query Neighborhood Hits	73	Target Neighborhood Hits	689	Shared Neighborhood Hits	3
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CENB1_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.053073 (rank : 81)
Query Neighborhood Hits	73	Target Neighborhood Hits	383	Shared Neighborhood Hits	11
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.057198 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.051807 (rank : 84)
Query Neighborhood Hits	73	Target Neighborhood Hits	395	Shared Neighborhood Hits	9
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CIP4_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.055430 (rank : 77)
Query Neighborhood Hits	73	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DAPP1_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.050578 (rank : 86)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

FA13A_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.070796 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.071856 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.055869 (rank : 76)
Query Neighborhood Hits	73	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.054408 (rank : 80)
Query Neighborhood Hits	73	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRAP_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.050226 (rank : 88)
Query Neighborhood Hits	73	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRP3_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.067972 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

NCK2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.056589 (rank : 75)
Query Neighborhood Hits	73	Target Neighborhood Hits	310	Shared Neighborhood Hits	15
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

P55G_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.050660 (rank : 85)
Query Neighborhood Hits	73	Target Neighborhood Hits	451	Shared Neighborhood Hits	5
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.050001 (rank : 89)
Query Neighborhood Hits	73	Target Neighborhood Hits	401	Shared Neighborhood Hits	5
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.092026 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.068973 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	519	Shared Neighborhood Hits	19
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCTL_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.054767 (rank : 79)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.055416 (rank : 78)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

Hits sorted by NC score

RHG08_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
NC score	0.993191 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG01_HUMAN
NC score	0.983910 (rank : 3)	θ value	4.1775e-114 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

3BP1_MOUSE
NC score	0.786485 (rank : 4)	θ value	1.058e-16 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	238	Shared Neighborhood Hits	62
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG09_HUMAN
NC score	0.774057 (rank : 5)	θ value	1.29331e-14 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG06_HUMAN
NC score	0.772893 (rank : 6)	θ value	2.60593e-15 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.771257 (rank : 7)	θ value	1.16975e-15 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_HUMAN
NC score	0.764716 (rank : 8)	θ value	6.62687e-19 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	376	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GMIP_HUMAN
NC score	0.755149 (rank : 9)	θ value	1.16975e-15 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
NC score	0.753030 (rank : 10)	θ value	1.09485e-13 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	202	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG12_MOUSE
NC score	0.751789 (rank : 11)	θ value	1.52774e-15 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
NC score	0.750468 (rank : 12)	θ value	1.29331e-14 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	190	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

TAGAP_HUMAN
NC score	0.737560 (rank : 13)	θ value	1.99529e-15 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
NC score	0.737396 (rank : 14)	θ value	1.52774e-15 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RGAP1_MOUSE
NC score	0.735788 (rank : 15)	θ value	2.69671e-12 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	185	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_HUMAN
NC score	0.733985 (rank : 16)	θ value	1.47974e-10 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG18_MOUSE
NC score	0.728081 (rank : 17)	θ value	1.33837e-11 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG18_HUMAN
NC score	0.724505 (rank : 18)	θ value	1.47974e-10 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

GRLF1_HUMAN
NC score	0.723594 (rank : 19)	θ value	1.33837e-11 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG25_MOUSE
NC score	0.719093 (rank : 20)	θ value	1.92812e-18 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	492	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CHIO_MOUSE
NC score	0.714975 (rank : 21)	θ value	3.40345e-15 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

TCGAP_MOUSE
NC score	0.703292 (rank : 22)	θ value	4.59992e-12 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	409	Shared Neighborhood Hits	62
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG25_HUMAN
NC score	0.701044 (rank : 23)	θ value	3.88503e-19 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	550	Shared Neighborhood Hits	60
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

OPHN1_HUMAN
NC score	0.697704 (rank : 24)	θ value	3.89403e-11 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
NC score	0.696699 (rank : 25)	θ value	1.74796e-11 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG05_MOUSE
NC score	0.695213 (rank : 26)	θ value	1.58096e-12 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CHIN_MOUSE
NC score	0.685244 (rank : 27)	θ value	9.90251e-15 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

SRGP2_HUMAN
NC score	0.684053 (rank : 28)	θ value	3.40345e-15 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

CHIO_HUMAN
NC score	0.683886 (rank : 29)	θ value	4.44505e-15 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	220	Shared Neighborhood Hits	61
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG04_HUMAN
NC score	0.683229 (rank : 30)	θ value	1.86753e-13 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	307	Shared Neighborhood Hits	62
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

CHIN_HUMAN
NC score	0.681360 (rank : 31)	θ value	1.68911e-14 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG05_HUMAN
NC score	0.680950 (rank : 32)	θ value	1.47974e-10 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	158	Shared Neighborhood Hits	62
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SRGP2_MOUSE
NC score	0.676586 (rank : 33)	θ value	3.76295e-14 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	324	Shared Neighborhood Hits	62
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

ABR_HUMAN
NC score	0.673291 (rank : 34)	θ value	6.41864e-14 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RBP1_MOUSE
NC score	0.671868 (rank : 35)	θ value	9.26847e-13 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	493	Shared Neighborhood Hits	60
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP1_HUMAN
NC score	0.665941 (rank : 36)	θ value	5.8054e-15 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	390	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
NC score	0.665768 (rank : 37)	θ value	3.40345e-15 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	432	Shared Neighborhood Hits	62
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

BCR_HUMAN
NC score	0.655575 (rank : 38)	θ value	7.09661e-13 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RBP1_HUMAN
NC score	0.655395 (rank : 39)	θ value	4.16044e-13 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	521	Shared Neighborhood Hits	60
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG26_HUMAN
NC score	0.652243 (rank : 40)	θ value	1.133e-10 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	281	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG07_MOUSE
NC score	0.637405 (rank : 41)	θ value	1.25267e-09 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.632113 (rank : 42)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TCGAP_HUMAN
NC score	0.624177 (rank : 43)	θ value	1.58096e-12 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	872	Shared Neighborhood Hits	62
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CE005_HUMAN
NC score	0.623579 (rank : 44)	θ value	1.33837e-11 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	213	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.621571 (rank : 45)	θ value	7.84624e-12 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	238	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

K1688_MOUSE
NC score	0.590182 (rank : 46)	θ value	4.30538e-10 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

STA13_HUMAN
NC score	0.589957 (rank : 47)	θ value	8.11959e-09 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STAR8_MOUSE
NC score	0.588802 (rank : 48)	θ value	1.29631e-06 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
NC score	0.579538 (rank : 49)	θ value	8.97725e-08 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STAR8_HUMAN
NC score	0.579198 (rank : 50)	θ value	4.92598e-06 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	216	Shared Neighborhood Hits	59
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

K1688_HUMAN
NC score	0.576728 (rank : 51)	θ value	5.62301e-10 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	217	Shared Neighborhood Hits	58
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND2_HUMAN
NC score	0.556336 (rank : 52)	θ value	1.9326e-10 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_MOUSE
NC score	0.494323 (rank : 53)	θ value	0.00175202 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	228	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.485125 (rank : 54)	θ value	0.00102713 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	275	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

BNIP2_HUMAN
NC score	0.470983 (rank : 55)	θ value	4.58923e-20 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
NC score	0.470895 (rank : 56)	θ value	1.5773e-20 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

ATCAY_MOUSE
NC score	0.462112 (rank : 57)	θ value	9.56915e-18 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

ATCAY_HUMAN
NC score	0.460451 (rank : 58)	θ value	9.56915e-18 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

BNIPL_MOUSE
NC score	0.457483 (rank : 59)	θ value	1.38178e-16 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

CEND1_MOUSE
NC score	0.455219 (rank : 60)	θ value	3.19293e-05 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	260	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

BNIPL_HUMAN
NC score	0.454863 (rank : 61)	θ value	2.13179e-17 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	40	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

CEND1_HUMAN
NC score	0.434586 (rank : 62)	θ value	0.000158464 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	284	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

I5P2_HUMAN
NC score	0.392125 (rank : 63)	θ value	3.08544e-08 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

MYO9B_MOUSE
NC score	0.389039 (rank : 64)	θ value	9.26847e-13 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	311	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.382835 (rank : 65)	θ value	4.59992e-12 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	641	Shared Neighborhood Hits	62
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

OCRL_HUMAN
NC score	0.381499 (rank : 66)	θ value	5.26297e-08 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85A_HUMAN
NC score	0.365595 (rank : 67)	θ value	1.29631e-06 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	479	Shared Neighborhood Hits	58
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.355955 (rank : 68)	θ value	3.77169e-06 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	435	Shared Neighborhood Hits	58
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85B_HUMAN
NC score	0.092026 (rank : 69)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	73	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

FA13A_MOUSE
NC score	0.071856 (rank : 70)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	73	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13A_HUMAN
NC score	0.070796 (rank : 71)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	73	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

P85B_MOUSE
NC score	0.068973 (rank : 72)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	73	Target Neighborhood Hits	519	Shared Neighborhood Hits	19
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GRP3_HUMAN
NC score	0.067972 (rank : 73)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	73	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

CENB2_HUMAN
NC score	0.057198 (rank : 74)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	73	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

NCK2_HUMAN
NC score	0.056589 (rank : 75)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	73	Target Neighborhood Hits	310	Shared Neighborhood Hits	15
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

FA13C_HUMAN
NC score	0.055869 (rank : 76)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	73	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

CIP4_HUMAN
NC score	0.055430 (rank : 77)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	73	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

PCTL_MOUSE
NC score	0.055416 (rank : 78)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.054767 (rank : 79)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

FA13C_MOUSE
NC score	0.054408 (rank : 80)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	73	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

CENB1_HUMAN
NC score	0.053073 (rank : 81)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	383	Shared Neighborhood Hits	11
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

NF1_HUMAN
NC score	0.052934 (rank : 82)	θ value	0.0193708 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P21359, O00662, Q14284, Q14930, Q9UMK3	Gene names	NF1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1) [Contains: Neurofibromin truncated].

NF1_MOUSE
NC score	0.052376 (rank : 83)	θ value	0.0252991 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q04690, Q61956, Q61957	Gene names	Nf1
Domain Architecture
Description	Neurofibromin (Neurofibromatosis-related protein NF-1).

CENB5_HUMAN
NC score	0.051807 (rank : 84)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	73	Target Neighborhood Hits	395	Shared Neighborhood Hits	9
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

P55G_HUMAN
NC score	0.050660 (rank : 85)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	73	Target Neighborhood Hits	451	Shared Neighborhood Hits	5
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

DAPP1_MOUSE
NC score	0.050578 (rank : 86)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	73	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

S14L2_HUMAN
NC score	0.050304 (rank : 87)	θ value	0.0330416 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O76054, Q9ULN4	Gene names	SEC14L2, KIAA1186
Domain Architecture
Description	SEC14-like protein 2 (Alpha-tocopherol-associated protein) (TAP) (hTAP) (Supernatant protein factor) (SPF) (Squalene transfer protein).

GRAP_HUMAN
NC score	0.050226 (rank : 88)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	73	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

P55G_MOUSE
NC score	0.050001 (rank : 89)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	73	Target Neighborhood Hits	401	Shared Neighborhood Hits	5
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

S14L2_MOUSE
NC score	0.049748 (rank : 90)	θ value	0.0431538 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q99J08	Gene names	Sec14l2
Domain Architecture
Description	SEC14-like protein 2 (Alpha-tocopherol-associated protein) (TAP).

AFAD_HUMAN
NC score	0.009196 (rank : 91)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	689	Shared Neighborhood Hits	3
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).