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Network neighborhood for query Sequence : GMIP_HUMAN

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GMIP_HUMAN
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GMIP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	225
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
θ value	0 (rank : 2)	NC score	0.984743 (rank : 2)
Query Neighborhood Hits	225	Target Neighborhood Hits	202	Shared Neighborhood Hits	128
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHIO_HUMAN
θ value	2.86786e-30 (rank : 3)	NC score	0.793492 (rank : 7)
Query Neighborhood Hits	225	Target Neighborhood Hits	220	Shared Neighborhood Hits	96
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	2.86786e-30 (rank : 4)	NC score	0.824621 (rank : 4)
Query Neighborhood Hits	225	Target Neighborhood Hits	130	Shared Neighborhood Hits	95
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_MOUSE
θ value	1.85889e-29 (rank : 5)	NC score	0.791340 (rank : 8)
Query Neighborhood Hits	225	Target Neighborhood Hits	229	Shared Neighborhood Hits	97
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
θ value	4.14116e-29 (rank : 6)	NC score	0.790142 (rank : 11)
Query Neighborhood Hits	225	Target Neighborhood Hits	227	Shared Neighborhood Hits	96
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

MYO9B_HUMAN
θ value	8.08199e-25 (rank : 7)	NC score	0.437986 (rank : 59)
Query Neighborhood Hits	225	Target Neighborhood Hits	641	Shared Neighborhood Hits	116
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	3.07116e-24 (rank : 8)	NC score	0.442410 (rank : 57)
Query Neighborhood Hits	225	Target Neighborhood Hits	311	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ABR_HUMAN
θ value	4.58923e-20 (rank : 9)	NC score	0.729183 (rank : 26)
Query Neighborhood Hits	225	Target Neighborhood Hits	166	Shared Neighborhood Hits	71
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

BCR_HUMAN
θ value	1.74391e-19 (rank : 10)	NC score	0.716255 (rank : 30)
Query Neighborhood Hits	225	Target Neighborhood Hits	204	Shared Neighborhood Hits	72
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG25_MOUSE
θ value	8.65492e-19 (rank : 11)	NC score	0.725506 (rank : 27)
Query Neighborhood Hits	225	Target Neighborhood Hits	492	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TCGAP_MOUSE
θ value	8.65492e-19 (rank : 12)	NC score	0.762887 (rank : 21)
Query Neighborhood Hits	225	Target Neighborhood Hits	409	Shared Neighborhood Hits	77
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

OPHN1_HUMAN
θ value	1.13037e-18 (rank : 13)	NC score	0.764935 (rank : 17)
Query Neighborhood Hits	225	Target Neighborhood Hits	161	Shared Neighborhood Hits	68
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
θ value	1.92812e-18 (rank : 14)	NC score	0.764328 (rank : 19)
Query Neighborhood Hits	225	Target Neighborhood Hits	174	Shared Neighborhood Hits	66
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG09_HUMAN
θ value	1.92812e-18 (rank : 15)	NC score	0.827561 (rank : 3)
Query Neighborhood Hits	225	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RGAP1_HUMAN
θ value	3.28887e-18 (rank : 16)	NC score	0.809889 (rank : 5)
Query Neighborhood Hits	225	Target Neighborhood Hits	189	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG12_MOUSE
θ value	3.28887e-18 (rank : 17)	NC score	0.790188 (rank : 10)
Query Neighborhood Hits	225	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

TCGAP_HUMAN
θ value	4.29542e-18 (rank : 18)	NC score	0.677516 (rank : 39)
Query Neighborhood Hits	225	Target Neighborhood Hits	872	Shared Neighborhood Hits	91
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG12_HUMAN
θ value	7.32683e-18 (rank : 19)	NC score	0.790994 (rank : 9)
Query Neighborhood Hits	225	Target Neighborhood Hits	190	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SRGP2_HUMAN
θ value	2.7842e-17 (rank : 20)	NC score	0.698279 (rank : 34)
Query Neighborhood Hits	225	Target Neighborhood Hits	331	Shared Neighborhood Hits	67
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	4.74913e-17 (rank : 21)	NC score	0.690785 (rank : 36)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	68
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG04_HUMAN
θ value	6.20254e-17 (rank : 22)	NC score	0.710346 (rank : 31)
Query Neighborhood Hits	225	Target Neighborhood Hits	307	Shared Neighborhood Hits	71
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG26_HUMAN
θ value	6.20254e-17 (rank : 23)	NC score	0.721728 (rank : 29)
Query Neighborhood Hits	225	Target Neighborhood Hits	281	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG01_HUMAN
θ value	1.80466e-16 (rank : 24)	NC score	0.766891 (rank : 16)
Query Neighborhood Hits	225	Target Neighborhood Hits	75	Shared Neighborhood Hits	63
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RGAP1_MOUSE
θ value	4.02038e-16 (rank : 25)	NC score	0.800940 (rank : 6)
Query Neighborhood Hits	225	Target Neighborhood Hits	185	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG08_MOUSE
θ value	1.16975e-15 (rank : 26)	NC score	0.755149 (rank : 23)
Query Neighborhood Hits	225	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

SRGP1_HUMAN
θ value	1.52774e-15 (rank : 27)	NC score	0.684420 (rank : 37)
Query Neighborhood Hits	225	Target Neighborhood Hits	390	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

3BP1_HUMAN
θ value	2.60593e-15 (rank : 28)	NC score	0.773710 (rank : 15)
Query Neighborhood Hits	225	Target Neighborhood Hits	376	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CEND2_HUMAN
θ value	7.58209e-15 (rank : 29)	NC score	0.628173 (rank : 46)
Query Neighborhood Hits	225	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RHG08_HUMAN
θ value	7.58209e-15 (rank : 30)	NC score	0.748255 (rank : 24)
Query Neighborhood Hits	225	Target Neighborhood Hits	88	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG25_HUMAN
θ value	7.58209e-15 (rank : 31)	NC score	0.700558 (rank : 33)
Query Neighborhood Hits	225	Target Neighborhood Hits	550	Shared Neighborhood Hits	92
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CE005_MOUSE
θ value	1.68911e-14 (rank : 32)	NC score	0.647979 (rank : 43)
Query Neighborhood Hits	225	Target Neighborhood Hits	238	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE005_HUMAN
θ value	2.20605e-14 (rank : 33)	NC score	0.649800 (rank : 42)
Query Neighborhood Hits	225	Target Neighborhood Hits	213	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

FNBP2_HUMAN
θ value	3.76295e-14 (rank : 34)	NC score	0.679490 (rank : 38)
Query Neighborhood Hits	225	Target Neighborhood Hits	432	Shared Neighborhood Hits	83
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GRLF1_HUMAN
θ value	3.76295e-14 (rank : 35)	NC score	0.764403 (rank : 18)
Query Neighborhood Hits	225	Target Neighborhood Hits	167	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG05_MOUSE
θ value	3.76295e-14 (rank : 36)	NC score	0.735033 (rank : 25)
Query Neighborhood Hits	225	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_HUMAN
θ value	1.42992e-13 (rank : 37)	NC score	0.779891 (rank : 13)
Query Neighborhood Hits	225	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG18_MOUSE
θ value	1.42992e-13 (rank : 38)	NC score	0.758644 (rank : 22)
Query Neighborhood Hits	225	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG05_HUMAN
θ value	1.86753e-13 (rank : 39)	NC score	0.725443 (rank : 28)
Query Neighborhood Hits	225	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_MOUSE
θ value	1.86753e-13 (rank : 40)	NC score	0.777554 (rank : 14)
Query Neighborhood Hits	225	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG18_HUMAN
θ value	1.86753e-13 (rank : 41)	NC score	0.763814 (rank : 20)
Query Neighborhood Hits	225	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RBP1_MOUSE
θ value	2.43908e-13 (rank : 42)	NC score	0.708018 (rank : 32)
Query Neighborhood Hits	225	Target Neighborhood Hits	493	Shared Neighborhood Hits	93
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

3BP1_MOUSE
θ value	4.16044e-13 (rank : 43)	NC score	0.784461 (rank : 12)
Query Neighborhood Hits	225	Target Neighborhood Hits	238	Shared Neighborhood Hits	74
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RBP1_HUMAN
θ value	5.43371e-13 (rank : 44)	NC score	0.691840 (rank : 35)
Query Neighborhood Hits	225	Target Neighborhood Hits	521	Shared Neighborhood Hits	94
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG07_MOUSE
θ value	7.09661e-13 (rank : 45)	NC score	0.668463 (rank : 40)
Query Neighborhood Hits	225	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
θ value	1.2105e-12 (rank : 46)	NC score	0.662249 (rank : 41)
Query Neighborhood Hits	225	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CEND3_MOUSE
θ value	6.00763e-12 (rank : 47)	NC score	0.586411 (rank : 51)
Query Neighborhood Hits	225	Target Neighborhood Hits	228	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
θ value	2.28291e-11 (rank : 48)	NC score	0.575396 (rank : 52)
Query Neighborhood Hits	225	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND1_MOUSE
θ value	8.67504e-11 (rank : 49)	NC score	0.535983 (rank : 53)
Query Neighborhood Hits	225	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

P85A_MOUSE
θ value	1.47974e-10 (rank : 50)	NC score	0.435001 (rank : 60)
Query Neighborhood Hits	225	Target Neighborhood Hits	435	Shared Neighborhood Hits	75
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CEND1_HUMAN
θ value	1.9326e-10 (rank : 51)	NC score	0.515791 (rank : 56)
Query Neighborhood Hits	225	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

P85A_HUMAN
θ value	9.59137e-10 (rank : 52)	NC score	0.438566 (rank : 58)
Query Neighborhood Hits	225	Target Neighborhood Hits	479	Shared Neighborhood Hits	80
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

STAR8_MOUSE
θ value	9.59137e-10 (rank : 53)	NC score	0.625705 (rank : 47)
Query Neighborhood Hits	225	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
θ value	3.64472e-09 (rank : 54)	NC score	0.617753 (rank : 48)
Query Neighborhood Hits	225	Target Neighborhood Hits	216	Shared Neighborhood Hits	63
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_HUMAN
θ value	2.36244e-08 (rank : 55)	NC score	0.612934 (rank : 49)
Query Neighborhood Hits	225	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
θ value	3.08544e-08 (rank : 56)	NC score	0.603612 (rank : 50)
Query Neighborhood Hits	225	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

OCRL_HUMAN
θ value	4.92598e-06 (rank : 57)	NC score	0.360686 (rank : 62)
Query Neighborhood Hits	225	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

I5P2_HUMAN
θ value	1.43324e-05 (rank : 58)	NC score	0.364019 (rank : 61)
Query Neighborhood Hits	225	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

K1688_HUMAN
θ value	2.44474e-05 (rank : 59)	NC score	0.520967 (rank : 55)
Query Neighborhood Hits	225	Target Neighborhood Hits	217	Shared Neighborhood Hits	69
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

P85B_HUMAN
θ value	0.000121331 (rank : 60)	NC score	0.176944 (rank : 63)
Query Neighborhood Hits	225	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

K1688_MOUSE
θ value	0.000158464 (rank : 61)	NC score	0.529033 (rank : 54)
Query Neighborhood Hits	225	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

TAGAP_HUMAN
θ value	0.00020696 (rank : 62)	NC score	0.637069 (rank : 44)
Query Neighborhood Hits	225	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

P85B_MOUSE
θ value	0.000270298 (rank : 63)	NC score	0.149719 (rank : 65)
Query Neighborhood Hits	225	Target Neighborhood Hits	519	Shared Neighborhood Hits	52
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RGS3_MOUSE
θ value	0.00228821 (rank : 64)	NC score	0.037060 (rank : 156)
Query Neighborhood Hits	225	Target Neighborhood Hits	1621	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TAGAP_MOUSE
θ value	0.00390308 (rank : 65)	NC score	0.633934 (rank : 45)
Query Neighborhood Hits	225	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

GRP3_HUMAN
θ value	0.00665767 (rank : 66)	NC score	0.162395 (rank : 64)
Query Neighborhood Hits	225	Target Neighborhood Hits	131	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

CYLN2_MOUSE
θ value	0.00869519 (rank : 67)	NC score	0.043409 (rank : 140)
Query Neighborhood Hits	225	Target Neighborhood Hits	1002	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

IQEC3_MOUSE
θ value	0.0330416 (rank : 68)	NC score	0.022936 (rank : 206)
Query Neighborhood Hits	225	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MAGE1_HUMAN
θ value	0.0431538 (rank : 69)	NC score	0.024746 (rank : 201)
Query Neighborhood Hits	225	Target Neighborhood Hits	1389	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ATX1_MOUSE
θ value	0.0736092 (rank : 70)	NC score	0.038358 (rank : 150)
Query Neighborhood Hits	225	Target Neighborhood Hits	264	Shared Neighborhood Hits	12
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

SPTN5_HUMAN
θ value	0.0961366 (rank : 71)	NC score	0.034100 (rank : 173)
Query Neighborhood Hits	225	Target Neighborhood Hits	674	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

TXLNA_HUMAN
θ value	0.0961366 (rank : 72)	NC score	0.032392 (rank : 179)
Query Neighborhood Hits	225	Target Neighborhood Hits	982	Shared Neighborhood Hits	53
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

MRCKA_HUMAN
θ value	0.125558 (rank : 73)	NC score	0.045073 (rank : 138)
Query Neighborhood Hits	225	Target Neighborhood Hits	1999	Shared Neighborhood Hits	104
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MYH11_HUMAN
θ value	0.163984 (rank : 74)	NC score	0.048144 (rank : 135)
Query Neighborhood Hits	225	Target Neighborhood Hits	1806	Shared Neighborhood Hits	80
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PERQ1_MOUSE
θ value	0.21417 (rank : 75)	NC score	0.051467 (rank : 129)
Query Neighborhood Hits	225	Target Neighborhood Hits	215	Shared Neighborhood Hits	17
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

PO3F4_HUMAN
θ value	0.21417 (rank : 76)	NC score	0.013543 (rank : 247)
Query Neighborhood Hits	225	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

TACC2_MOUSE
θ value	0.21417 (rank : 77)	NC score	0.058232 (rank : 103)
Query Neighborhood Hits	225	Target Neighborhood Hits	774	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

MEIS2_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.022158 (rank : 209)
Query Neighborhood Hits	225	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	O14770, Q96KI4, Q96KI5, Q9NRS1, Q9NRS2, Q9NRS3	Gene names	MEIS2, MRG1
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

MEIS2_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.022338 (rank : 208)
Query Neighborhood Hits	225	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

TACC2_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.056283 (rank : 111)
Query Neighborhood Hits	225	Target Neighborhood Hits	856	Shared Neighborhood Hits	57
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TTLL5_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.020536 (rank : 217)
Query Neighborhood Hits	225	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

CCD62_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.041513 (rank : 143)
Query Neighborhood Hits	225	Target Neighborhood Hits	631	Shared Neighborhood Hits	49
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

KPCI_MOUSE
θ value	0.365318 (rank : 83)	NC score	0.030907 (rank : 182)
Query Neighborhood Hits	225	Target Neighborhood Hits	888	Shared Neighborhood Hits	47
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

ZN447_HUMAN
θ value	0.365318 (rank : 84)	NC score	0.001468 (rank : 275)
Query Neighborhood Hits	225	Target Neighborhood Hits	899	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

KPCI_HUMAN
θ value	0.47712 (rank : 85)	NC score	0.030766 (rank : 183)
Query Neighborhood Hits	225	Target Neighborhood Hits	885	Shared Neighborhood Hits	47
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

MRCKB_MOUSE
θ value	0.47712 (rank : 86)	NC score	0.042117 (rank : 142)
Query Neighborhood Hits	225	Target Neighborhood Hits	2180	Shared Neighborhood Hits	107
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MYH11_MOUSE
θ value	0.47712 (rank : 87)	NC score	0.047918 (rank : 137)
Query Neighborhood Hits	225	Target Neighborhood Hits	1777	Shared Neighborhood Hits	79
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

OPTN_MOUSE
θ value	0.47712 (rank : 88)	NC score	0.029842 (rank : 186)
Query Neighborhood Hits	225	Target Neighborhood Hits	1120	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

KSR1_HUMAN
θ value	0.62314 (rank : 89)	NC score	0.020146 (rank : 223)
Query Neighborhood Hits	225	Target Neighborhood Hits	867	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

KSR1_MOUSE
θ value	0.62314 (rank : 90)	NC score	0.020918 (rank : 214)
Query Neighborhood Hits	225	Target Neighborhood Hits	870	Shared Neighborhood Hits	39
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

MEF2C_MOUSE
θ value	0.62314 (rank : 91)	NC score	0.024473 (rank : 203)
Query Neighborhood Hits	225	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20	Gene names	Mef2c
Domain Architecture	No domain graphic available
Description	Myocyte-specific enhancer factor 2C.

RARG1_HUMAN
θ value	0.62314 (rank : 92)	NC score	0.011245 (rank : 253)
Query Neighborhood Hits	225	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_HUMAN
θ value	0.62314 (rank : 93)	NC score	0.011171 (rank : 254)
Query Neighborhood Hits	225	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

UN13B_MOUSE
θ value	0.62314 (rank : 94)	NC score	0.107463 (rank : 68)
Query Neighborhood Hits	225	Target Neighborhood Hits	210	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

ZIMP7_MOUSE
θ value	0.62314 (rank : 95)	NC score	0.018424 (rank : 232)
Query Neighborhood Hits	225	Target Neighborhood Hits	566	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CSPG5_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.028003 (rank : 192)
Query Neighborhood Hits	225	Target Neighborhood Hits	199	Shared Neighborhood Hits	11
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

KPCE_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.038880 (rank : 146)
Query Neighborhood Hits	225	Target Neighborhood Hits	906	Shared Neighborhood Hits	45
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
θ value	0.813845 (rank : 98)	NC score	0.038857 (rank : 147)
Query Neighborhood Hits	225	Target Neighborhood Hits	906	Shared Neighborhood Hits	45
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCT_HUMAN
θ value	0.813845 (rank : 99)	NC score	0.037598 (rank : 155)
Query Neighborhood Hits	225	Target Neighborhood Hits	897	Shared Neighborhood Hits	46
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	0.813845 (rank : 100)	NC score	0.037677 (rank : 154)
Query Neighborhood Hits	225	Target Neighborhood Hits	895	Shared Neighborhood Hits	46
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

MEF2C_HUMAN
θ value	0.813845 (rank : 101)	NC score	0.024817 (rank : 200)
Query Neighborhood Hits	225	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

MLL3_HUMAN
θ value	0.813845 (rank : 102)	NC score	0.016131 (rank : 237)
Query Neighborhood Hits	225	Target Neighborhood Hits	1644	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NIN_MOUSE
θ value	0.813845 (rank : 103)	NC score	0.036816 (rank : 160)
Query Neighborhood Hits	225	Target Neighborhood Hits	1376	Shared Neighborhood Hits	67
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PLXB1_HUMAN
θ value	0.813845 (rank : 104)	NC score	0.013453 (rank : 248)
Query Neighborhood Hits	225	Target Neighborhood Hits	360	Shared Neighborhood Hits	20
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

UN13B_HUMAN
θ value	0.813845 (rank : 105)	NC score	0.111207 (rank : 66)
Query Neighborhood Hits	225	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

AMZ1_MOUSE
θ value	1.06291 (rank : 106)	NC score	0.020461 (rank : 219)
Query Neighborhood Hits	225	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVF9, Q811F9, Q8BMM5	Gene names	Amz1
Domain Architecture	No domain graphic available
Description	Archaemetzincin-1 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 1).

B4GT1_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.011598 (rank : 251)
Query Neighborhood Hits	225	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CK5P2_HUMAN
θ value	1.06291 (rank : 108)	NC score	0.037715 (rank : 153)
Query Neighborhood Hits	225	Target Neighborhood Hits	1433	Shared Neighborhood Hits	70
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

KSR2_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.021409 (rank : 211)
Query Neighborhood Hits	225	Target Neighborhood Hits	920	Shared Neighborhood Hits	47
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

LRSM1_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.030212 (rank : 184)
Query Neighborhood Hits	225	Target Neighborhood Hits	1078	Shared Neighborhood Hits	57
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MRCKB_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.039729 (rank : 144)
Query Neighborhood Hits	225	Target Neighborhood Hits	2239	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PPIP2_MOUSE
θ value	1.06291 (rank : 112)	NC score	0.024704 (rank : 202)
Query Neighborhood Hits	225	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

STX12_MOUSE
θ value	1.06291 (rank : 113)	NC score	0.028722 (rank : 190)
Query Neighborhood Hits	225	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

UN13A_HUMAN
θ value	1.06291 (rank : 114)	NC score	0.109114 (rank : 67)
Query Neighborhood Hits	225	Target Neighborhood Hits	285	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

CCHCR_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.035265 (rank : 166)
Query Neighborhood Hits	225	Target Neighborhood Hits	717	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CENPE_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.029727 (rank : 187)
Query Neighborhood Hits	225	Target Neighborhood Hits	2060	Shared Neighborhood Hits	81
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CEP55_MOUSE
θ value	1.38821 (rank : 117)	NC score	0.038327 (rank : 151)
Query Neighborhood Hits	225	Target Neighborhood Hits	693	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CNTRB_MOUSE
θ value	1.38821 (rank : 118)	NC score	0.025889 (rank : 196)
Query Neighborhood Hits	225	Target Neighborhood Hits	1029	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

KPCB_HUMAN
θ value	1.38821 (rank : 119)	NC score	0.036823 (rank : 159)
Query Neighborhood Hits	225	Target Neighborhood Hits	1121	Shared Neighborhood Hits	49
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	1.38821 (rank : 120)	NC score	0.037025 (rank : 157)
Query Neighborhood Hits	225	Target Neighborhood Hits	1117	Shared Neighborhood Hits	49
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

LRSM1_MOUSE
θ value	1.38821 (rank : 121)	NC score	0.022873 (rank : 207)
Query Neighborhood Hits	225	Target Neighborhood Hits	874	Shared Neighborhood Hits	45
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

NRCAM_HUMAN
θ value	1.38821 (rank : 122)	NC score	0.004342 (rank : 270)
Query Neighborhood Hits	225	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	1.38821 (rank : 123)	NC score	0.004322 (rank : 271)
Query Neighborhood Hits	225	Target Neighborhood Hits	432	Shared Neighborhood Hits	6
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

RASF7_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.025188 (rank : 199)
Query Neighborhood Hits	225	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

ANR26_MOUSE
θ value	1.81305 (rank : 125)	NC score	0.023847 (rank : 204)
Query Neighborhood Hits	225	Target Neighborhood Hits	1554	Shared Neighborhood Hits	71
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DVL3_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.010706 (rank : 257)
Query Neighborhood Hits	225	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

HXB3_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.001633 (rank : 274)
Query Neighborhood Hits	225	Target Neighborhood Hits	559	Shared Neighborhood Hits	17
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

MBB1A_HUMAN
θ value	1.81305 (rank : 128)	NC score	0.025511 (rank : 197)
Query Neighborhood Hits	225	Target Neighborhood Hits	665	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PO3F4_MOUSE
θ value	1.81305 (rank : 129)	NC score	0.010631 (rank : 258)
Query Neighborhood Hits	225	Target Neighborhood Hits	281	Shared Neighborhood Hits	5
SwissProt Accessions	P62515, P25216	Gene names	Pou3f4, Brn-4, Brn4, Otf9
Domain Architecture	No domain graphic available
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

SALL1_MOUSE
θ value	1.81305 (rank : 130)	NC score	-0.003020 (rank : 282)
Query Neighborhood Hits	225	Target Neighborhood Hits	826	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

SLK_MOUSE
θ value	1.81305 (rank : 131)	NC score	0.014337 (rank : 243)
Query Neighborhood Hits	225	Target Neighborhood Hits	1798	Shared Neighborhood Hits	91
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

F10A5_HUMAN
θ value	2.36792 (rank : 132)	NC score	0.010289 (rank : 259)
Query Neighborhood Hits	225	Target Neighborhood Hits	277	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

KPCL_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.036884 (rank : 158)
Query Neighborhood Hits	225	Target Neighborhood Hits	887	Shared Neighborhood Hits	45
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCL_MOUSE
θ value	2.36792 (rank : 134)	NC score	0.036492 (rank : 161)
Query Neighborhood Hits	225	Target Neighborhood Hits	891	Shared Neighborhood Hits	45
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

NDE1_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.031446 (rank : 181)
Query Neighborhood Hits	225	Target Neighborhood Hits	823	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

RERE_MOUSE
θ value	2.36792 (rank : 136)	NC score	0.025243 (rank : 198)
Query Neighborhood Hits	225	Target Neighborhood Hits	785	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TRIP6_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.009712 (rank : 261)
Query Neighborhood Hits	225	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

VIME_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.015739 (rank : 238)
Query Neighborhood Hits	225	Target Neighborhood Hits	706	Shared Neighborhood Hits	52
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

BCL9_MOUSE
θ value	3.0926 (rank : 139)	NC score	0.020130 (rank : 224)
Query Neighborhood Hits	225	Target Neighborhood Hits	770	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CAR10_HUMAN
θ value	3.0926 (rank : 140)	NC score	0.020469 (rank : 218)
Query Neighborhood Hits	225	Target Neighborhood Hits	569	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

GAS7_MOUSE
θ value	3.0926 (rank : 141)	NC score	0.047940 (rank : 136)
Query Neighborhood Hits	225	Target Neighborhood Hits	259	Shared Neighborhood Hits	27
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GOGB1_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.035305 (rank : 164)
Query Neighborhood Hits	225	Target Neighborhood Hits	2297	Shared Neighborhood Hits	85
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

KPCD2_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.032898 (rank : 178)
Query Neighborhood Hits	225	Target Neighborhood Hits	910	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

KPCD_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.038990 (rank : 145)
Query Neighborhood Hits	225	Target Neighborhood Hits	900	Shared Neighborhood Hits	47
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCD_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.038814 (rank : 148)
Query Neighborhood Hits	225	Target Neighborhood Hits	888	Shared Neighborhood Hits	47
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

LR37B_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.011483 (rank : 252)
Query Neighborhood Hits	225	Target Neighborhood Hits	392	Shared Neighborhood Hits	14
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MK07_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.006835 (rank : 268)
Query Neighborhood Hits	225	Target Neighborhood Hits	1087	Shared Neighborhood Hits	50
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

NOTC2_HUMAN
θ value	3.0926 (rank : 148)	NC score	-0.000602 (rank : 280)
Query Neighborhood Hits	225	Target Neighborhood Hits	1113	Shared Neighborhood Hits	20
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PAK4_MOUSE
θ value	3.0926 (rank : 149)	NC score	0.008277 (rank : 267)
Query Neighborhood Hits	225	Target Neighborhood Hits	1098	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PI5PA_HUMAN
θ value	3.0926 (rank : 150)	NC score	0.044592 (rank : 139)
Query Neighborhood Hits	225	Target Neighborhood Hits	749	Shared Neighborhood Hits	34
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RARG1_MOUSE
θ value	3.0926 (rank : 151)	NC score	0.009669 (rank : 262)
Query Neighborhood Hits	225	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.009580 (rank : 263)
Query Neighborhood Hits	225	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

TRAK1_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.033179 (rank : 176)
Query Neighborhood Hits	225	Target Neighborhood Hits	660	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

ZDHC1_HUMAN
θ value	3.0926 (rank : 154)	NC score	0.014118 (rank : 246)
Query Neighborhood Hits	225	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

3BP5_MOUSE
θ value	4.03905 (rank : 155)	NC score	0.020806 (rank : 216)
Query Neighborhood Hits	225	Target Neighborhood Hits	346	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

CCHCR_MOUSE
θ value	4.03905 (rank : 156)	NC score	0.033077 (rank : 177)
Query Neighborhood Hits	225	Target Neighborhood Hits	932	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CIC_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.023131 (rank : 205)
Query Neighborhood Hits	225	Target Neighborhood Hits	992	Shared Neighborhood Hits	40
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

COKA1_HUMAN
θ value	4.03905 (rank : 158)	NC score	0.004410 (rank : 269)
Query Neighborhood Hits	225	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

DGKQ_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.079616 (rank : 73)
Query Neighborhood Hits	225	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

KPCD1_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.034440 (rank : 171)
Query Neighborhood Hits	225	Target Neighborhood Hits	901	Shared Neighborhood Hits	47
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

LRC49_HUMAN
θ value	4.03905 (rank : 161)	NC score	0.016856 (rank : 234)
Query Neighborhood Hits	225	Target Neighborhood Hits	210	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUZ0, Q9NXM6	Gene names	LRRC49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4).

MDC1_HUMAN
θ value	4.03905 (rank : 162)	NC score	0.026119 (rank : 194)
Query Neighborhood Hits	225	Target Neighborhood Hits	1446	Shared Neighborhood Hits	53
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SEH1L_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.009123 (rank : 264)
Query Neighborhood Hits	225	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EE3, Q8NFU6, Q96MH3, Q9C069	Gene names	SEH1L, SEC13L, SEH1
Domain Architecture
Description	Nucleoporin SEH1-like (SEC13-like protein).

SEN54_HUMAN
θ value	4.03905 (rank : 164)	NC score	0.019199 (rank : 228)
Query Neighborhood Hits	225	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

TEX14_MOUSE
θ value	4.03905 (rank : 165)	NC score	0.009845 (rank : 260)
Query Neighborhood Hits	225	Target Neighborhood Hits	1333	Shared Neighborhood Hits	56
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

VIME_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.016359 (rank : 236)
Query Neighborhood Hits	225	Target Neighborhood Hits	716	Shared Neighborhood Hits	54
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

ZN662_HUMAN
θ value	4.03905 (rank : 167)	NC score	-0.006041 (rank : 284)
Query Neighborhood Hits	225	Target Neighborhood Hits	738	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZS27, Q6ZNF8, Q6ZQW8	Gene names	ZNF662
Domain Architecture	No domain graphic available
Description	Zinc finger protein 662.

BTBD7_HUMAN
θ value	5.27518 (rank : 168)	NC score	0.008505 (rank : 266)
Query Neighborhood Hits	225	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

DGCR8_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.011895 (rank : 250)
Query Neighborhood Hits	225	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

G45IP_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.029367 (rank : 188)
Query Neighborhood Hits	225	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

KPCD1_MOUSE
θ value	5.27518 (rank : 171)	NC score	0.033838 (rank : 175)
Query Neighborhood Hits	225	Target Neighborhood Hits	891	Shared Neighborhood Hits	49
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD3_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.034998 (rank : 169)
Query Neighborhood Hits	225	Target Neighborhood Hits	895	Shared Neighborhood Hits	47
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

KPCD3_MOUSE
θ value	5.27518 (rank : 173)	NC score	0.034288 (rank : 172)
Query Neighborhood Hits	225	Target Neighborhood Hits	901	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

SELPL_MOUSE
θ value	5.27518 (rank : 174)	NC score	0.029314 (rank : 189)
Query Neighborhood Hits	225	Target Neighborhood Hits	588	Shared Neighborhood Hits	27
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SMOO_HUMAN
θ value	5.27518 (rank : 175)	NC score	0.027761 (rank : 193)
Query Neighborhood Hits	225	Target Neighborhood Hits	391	Shared Neighborhood Hits	23
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SSBP4_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.015615 (rank : 240)
Query Neighborhood Hits	225	Target Neighborhood Hits	753	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TMUB2_MOUSE
θ value	5.27518 (rank : 177)	NC score	0.011068 (rank : 255)
Query Neighborhood Hits	225	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q3V209, Q8K0X0, Q91YQ0, Q9D8C5	Gene names	Tmub2
Domain Architecture	No domain graphic available
Description	Transmembrane and ubiquitin-like domain-containing protein 2.

U2AFM_MOUSE
θ value	5.27518 (rank : 178)	NC score	0.028640 (rank : 191)
Query Neighborhood Hits	225	Target Neighborhood Hits	543	Shared Neighborhood Hits	42
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

ZN232_HUMAN
θ value	5.27518 (rank : 179)	NC score	-0.005843 (rank : 283)
Query Neighborhood Hits	225	Target Neighborhood Hits	754	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).

3BP5_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.019560 (rank : 227)
Query Neighborhood Hits	225	Target Neighborhood Hits	375	Shared Neighborhood Hits	27
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

ADA12_MOUSE
θ value	6.88961 (rank : 181)	NC score	0.002235 (rank : 273)
Query Neighborhood Hits	225	Target Neighborhood Hits	474	Shared Neighborhood Hits	16
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ATX7_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.017123 (rank : 233)
Query Neighborhood Hits	225	Target Neighborhood Hits	351	Shared Neighborhood Hits	17
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CP46A_MOUSE
θ value	6.88961 (rank : 183)	NC score	0.000657 (rank : 277)
Query Neighborhood Hits	225	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVK8	Gene names	Cyp46a1, Cyp46
Domain Architecture
Description	Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol 24-hydroxylase) (CH24H).

DMP1_MOUSE
θ value	6.88961 (rank : 184)	NC score	0.019617 (rank : 226)
Query Neighborhood Hits	225	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

GLE1_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.020830 (rank : 215)
Query Neighborhood Hits	225	Target Neighborhood Hits	504	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

HMMR_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.035291 (rank : 165)
Query Neighborhood Hits	225	Target Neighborhood Hits	1178	Shared Neighborhood Hits	66
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOOK3_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.036142 (rank : 162)
Query Neighborhood Hits	225	Target Neighborhood Hits	1070	Shared Neighborhood Hits	63
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

IRX5_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.015007 (rank : 241)
Query Neighborhood Hits	225	Target Neighborhood Hits	362	Shared Neighborhood Hits	17
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

IRX5_MOUSE
θ value	6.88961 (rank : 189)	NC score	0.014771 (rank : 242)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

KIF5A_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.019040 (rank : 229)
Query Neighborhood Hits	225	Target Neighborhood Hits	843	Shared Neighborhood Hits	50
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5A_MOUSE
θ value	6.88961 (rank : 191)	NC score	0.018653 (rank : 231)
Query Neighborhood Hits	225	Target Neighborhood Hits	859	Shared Neighborhood Hits	51
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5C_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.020242 (rank : 222)
Query Neighborhood Hits	225	Target Neighborhood Hits	974	Shared Neighborhood Hits	62
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_MOUSE
θ value	6.88961 (rank : 193)	NC score	0.020969 (rank : 213)
Query Neighborhood Hits	225	Target Neighborhood Hits	1040	Shared Neighborhood Hits	62
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KPCG_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.035216 (rank : 167)
Query Neighborhood Hits	225	Target Neighborhood Hits	1126	Shared Neighborhood Hits	48
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	6.88961 (rank : 195)	NC score	0.035311 (rank : 163)
Query Neighborhood Hits	225	Target Neighborhood Hits	1123	Shared Neighborhood Hits	48
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MY18A_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.048310 (rank : 134)
Query Neighborhood Hits	225	Target Neighborhood Hits	1929	Shared Neighborhood Hits	84
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PCLO_HUMAN
θ value	6.88961 (rank : 197)	NC score	0.038115 (rank : 152)
Query Neighborhood Hits	225	Target Neighborhood Hits	2046	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SRBS1_HUMAN
θ value	6.88961 (rank : 198)	NC score	0.067174 (rank : 89)
Query Neighborhood Hits	225	Target Neighborhood Hits	396	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STRN4_MOUSE
θ value	6.88961 (rank : 199)	NC score	-0.000005 (rank : 279)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	3
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

ZCHC6_HUMAN
θ value	6.88961 (rank : 200)	NC score	0.010880 (rank : 256)
Query Neighborhood Hits	225	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

CASB_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.012115 (rank : 249)
Query Neighborhood Hits	225	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P10598, Q543D9, Q8VCT6, Q8VCU8, Q91VI5, Q922Y5, Q9D1U6, Q9D1U7	Gene names	Csn2, Csnb
Domain Architecture
Description	Beta-casein precursor.

CCD91_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.020380 (rank : 221)
Query Neighborhood Hits	225	Target Neighborhood Hits	699	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CSKI2_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.014125 (rank : 245)
Query Neighborhood Hits	225	Target Neighborhood Hits	747	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DDX51_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.001209 (rank : 276)
Query Neighborhood Hits	225	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

ENAH_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.038378 (rank : 149)
Query Neighborhood Hits	225	Target Neighborhood Hits	919	Shared Neighborhood Hits	67
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.014171 (rank : 244)
Query Neighborhood Hits	225	Target Neighborhood Hits	821	Shared Neighborhood Hits	34
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GAS7_HUMAN
θ value	8.99809 (rank : 207)	NC score	0.042842 (rank : 141)
Query Neighborhood Hits	225	Target Neighborhood Hits	258	Shared Neighborhood Hits	27
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

GOGA5_MOUSE
θ value	8.99809 (rank : 208)	NC score	0.030049 (rank : 185)
Query Neighborhood Hits	225	Target Neighborhood Hits	1434	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

HOOK3_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.031965 (rank : 180)
Query Neighborhood Hits	225	Target Neighborhood Hits	1007	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

IDLC_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.016486 (rank : 235)
Query Neighborhood Hits	225	Target Neighborhood Hits	348	Shared Neighborhood Hits	26
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

IDLC_MOUSE
θ value	8.99809 (rank : 211)	NC score	0.015727 (rank : 239)
Query Neighborhood Hits	225	Target Neighborhood Hits	321	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

IFT81_MOUSE
θ value	8.99809 (rank : 212)	NC score	0.020408 (rank : 220)
Query Neighborhood Hits	225	Target Neighborhood Hits	959	Shared Neighborhood Hits	52
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

KPCA_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.034739 (rank : 170)
Query Neighborhood Hits	225	Target Neighborhood Hits	1070	Shared Neighborhood Hits	50
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
θ value	8.99809 (rank : 214)	NC score	0.034008 (rank : 174)
Query Neighborhood Hits	225	Target Neighborhood Hits	1067	Shared Neighborhood Hits	50
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

MACF1_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.021783 (rank : 210)
Query Neighborhood Hits	225	Target Neighborhood Hits	1313	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MD1L1_MOUSE
θ value	8.99809 (rank : 216)	NC score	0.019633 (rank : 225)
Query Neighborhood Hits	225	Target Neighborhood Hits	1001	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MRIP_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.035099 (rank : 168)
Query Neighborhood Hits	225	Target Neighborhood Hits	578	Shared Neighborhood Hits	51
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

NCOA6_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.021028 (rank : 212)
Query Neighborhood Hits	225	Target Neighborhood Hits	1202	Shared Neighborhood Hits	46
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NU214_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.019013 (rank : 230)
Query Neighborhood Hits	225	Target Neighborhood Hits	657	Shared Neighborhood Hits	36
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUMA1_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.025940 (rank : 195)
Query Neighborhood Hits	225	Target Neighborhood Hits	1523	Shared Neighborhood Hits	67
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PCDB4_HUMAN
θ value	8.99809 (rank : 221)	NC score	-0.002214 (rank : 281)
Query Neighborhood Hits	225	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5E5	Gene names	PCDHB4
Domain Architecture
Description	Protocadherin beta 4 precursor (PCDH-beta4).

PDZD8_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.098804 (rank : 69)
Query Neighborhood Hits	225	Target Neighborhood Hits	185	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

RFX1_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.008785 (rank : 265)
Query Neighborhood Hits	225	Target Neighborhood Hits	256	Shared Neighborhood Hits	19
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

ROBO3_MOUSE
θ value	8.99809 (rank : 224)	NC score	0.000382 (rank : 278)
Query Neighborhood Hits	225	Target Neighborhood Hits	524	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

UBP24_HUMAN
θ value	8.99809 (rank : 225)	NC score	0.004074 (rank : 272)
Query Neighborhood Hits	225	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

ATCAY_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.054187 (rank : 117)
Query Neighborhood Hits	225	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATCAY_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.054694 (rank : 116)
Query Neighborhood Hits	225	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

BNIP2_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.057487 (rank : 105)
Query Neighborhood Hits	225	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.057401 (rank : 106)
Query Neighborhood Hits	225	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIPL_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.053189 (rank : 120)
Query Neighborhood Hits	225	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.053271 (rank : 119)
Query Neighborhood Hits	225	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

CENA2_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.053026 (rank : 123)
Query Neighborhood Hits	225	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.072650 (rank : 83)
Query Neighborhood Hits	225	Target Neighborhood Hits	383	Shared Neighborhood Hits	17
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.078564 (rank : 74)
Query Neighborhood Hits	225	Target Neighborhood Hits	425	Shared Neighborhood Hits	25
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.073229 (rank : 81)
Query Neighborhood Hits	225	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CIP4_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.067309 (rank : 88)
Query Neighborhood Hits	225	Target Neighborhood Hits	374	Shared Neighborhood Hits	35
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DAPP1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.064253 (rank : 93)
Query Neighborhood Hits	225	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.066991 (rank : 90)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDEF1_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.051386 (rank : 130)
Query Neighborhood Hits	225	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.058009 (rank : 104)
Query Neighborhood Hits	225	Target Neighborhood Hits	599	Shared Neighborhood Hits	30
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.056591 (rank : 109)
Query Neighborhood Hits	225	Target Neighborhood Hits	625	Shared Neighborhood Hits	27
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.053074 (rank : 121)
Query Neighborhood Hits	225	Target Neighborhood Hits	353	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKD_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.061519 (rank : 96)
Query Neighborhood Hits	225	Target Neighborhood Hits	231	Shared Neighborhood Hits	47
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.068401 (rank : 85)
Query Neighborhood Hits	225	Target Neighborhood Hits	255	Shared Neighborhood Hits	46
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

FA13A_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.075858 (rank : 76)
Query Neighborhood Hits	225	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.076333 (rank : 75)
Query Neighborhood Hits	225	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.059093 (rank : 102)
Query Neighborhood Hits	225	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.057106 (rank : 108)
Query Neighborhood Hits	225	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRAP_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.063050 (rank : 95)
Query Neighborhood Hits	225	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.060025 (rank : 99)
Query Neighborhood Hits	225	Target Neighborhood Hits	309	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.061037 (rank : 97)
Query Neighborhood Hits	225	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.061017 (rank : 98)
Query Neighborhood Hits	225	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

ITSN1_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.055296 (rank : 113)
Query Neighborhood Hits	225	Target Neighborhood Hits	1757	Shared Neighborhood Hits	98
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.054764 (rank : 115)
Query Neighborhood Hits	225	Target Neighborhood Hits	1669	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.050576 (rank : 131)
Query Neighborhood Hits	225	Target Neighborhood Hits	1173	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MYO10_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.063991 (rank : 94)
Query Neighborhood Hits	225	Target Neighborhood Hits	920	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO1F_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.052083 (rank : 124)
Query Neighborhood Hits	225	Target Neighborhood Hits	275	Shared Neighborhood Hits	18
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.052013 (rank : 126)
Query Neighborhood Hits	225	Target Neighborhood Hits	262	Shared Neighborhood Hits	14
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

NCK2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.067811 (rank : 86)
Query Neighborhood Hits	225	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

P55G_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.098469 (rank : 70)
Query Neighborhood Hits	225	Target Neighborhood Hits	451	Shared Neighborhood Hits	27
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.098038 (rank : 71)
Query Neighborhood Hits	225	Target Neighborhood Hits	401	Shared Neighborhood Hits	28
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PCTL_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.059158 (rank : 101)
Query Neighborhood Hits	225	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.059833 (rank : 100)
Query Neighborhood Hits	225	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PKHA1_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.053311 (rank : 118)
Query Neighborhood Hits	225	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RASF1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.067455 (rank : 87)
Query Neighborhood Hits	225	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF1_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.082913 (rank : 72)
Query Neighborhood Hits	225	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

RASF5_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.050072 (rank : 133)
Query Neighborhood Hits	225	Target Neighborhood Hits	79	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

SMAP1_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.051557 (rank : 128)
Query Neighborhood Hits	225	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.050245 (rank : 132)
Query Neighborhood Hits	225	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.052018 (rank : 125)
Query Neighborhood Hits	225	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.051835 (rank : 127)
Query Neighborhood Hits	225	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SRBS1_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.055270 (rank : 114)
Query Neighborhood Hits	225	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAC3_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.072928 (rank : 82)
Query Neighborhood Hits	225	Target Neighborhood Hits	228	Shared Neighborhood Hits	43
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.074819 (rank : 79)
Query Neighborhood Hits	225	Target Neighborhood Hits	232	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.068412 (rank : 84)
Query Neighborhood Hits	225	Target Neighborhood Hits	276	Shared Neighborhood Hits	46
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.073230 (rank : 80)
Query Neighborhood Hits	225	Target Neighborhood Hits	268	Shared Neighborhood Hits	45
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

VAV2_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.065904 (rank : 92)
Query Neighborhood Hits	225	Target Neighborhood Hits	453	Shared Neighborhood Hits	51
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.066207 (rank : 91)
Query Neighborhood Hits	225	Target Neighborhood Hits	456	Shared Neighborhood Hits	51
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.075406 (rank : 77)
Query Neighborhood Hits	225	Target Neighborhood Hits	398	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.075220 (rank : 78)
Query Neighborhood Hits	225	Target Neighborhood Hits	404	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.056018 (rank : 112)
Query Neighborhood Hits	225	Target Neighborhood Hits	452	Shared Neighborhood Hits	58
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.057326 (rank : 107)
Query Neighborhood Hits	225	Target Neighborhood Hits	430	Shared Neighborhood Hits	51
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VINEX_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.053031 (rank : 122)
Query Neighborhood Hits	225	Target Neighborhood Hits	270	Shared Neighborhood Hits	18
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.056418 (rank : 110)
Query Neighborhood Hits	225	Target Neighborhood Hits	286	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

Hits sorted by NC score

GMIP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	225
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
NC score	0.984743 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	225	Target Neighborhood Hits	202	Shared Neighborhood Hits	128
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG09_HUMAN
NC score	0.827561 (rank : 3)	θ value	1.92812e-18 (rank : 15)
Query Neighborhood Hits	225	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CHIO_MOUSE
NC score	0.824621 (rank : 4)	θ value	2.86786e-30 (rank : 4)
Query Neighborhood Hits	225	Target Neighborhood Hits	130	Shared Neighborhood Hits	95
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RGAP1_HUMAN
NC score	0.809889 (rank : 5)	θ value	3.28887e-18 (rank : 16)
Query Neighborhood Hits	225	Target Neighborhood Hits	189	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
NC score	0.800940 (rank : 6)	θ value	4.02038e-16 (rank : 25)
Query Neighborhood Hits	225	Target Neighborhood Hits	185	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CHIO_HUMAN
NC score	0.793492 (rank : 7)	θ value	2.86786e-30 (rank : 3)
Query Neighborhood Hits	225	Target Neighborhood Hits	220	Shared Neighborhood Hits	96
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_MOUSE
NC score	0.791340 (rank : 8)	θ value	1.85889e-29 (rank : 5)
Query Neighborhood Hits	225	Target Neighborhood Hits	229	Shared Neighborhood Hits	97
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG12_HUMAN
NC score	0.790994 (rank : 9)	θ value	7.32683e-18 (rank : 19)
Query Neighborhood Hits	225	Target Neighborhood Hits	190	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.790188 (rank : 10)	θ value	3.28887e-18 (rank : 17)
Query Neighborhood Hits	225	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHIN_HUMAN
NC score	0.790142 (rank : 11)	θ value	4.14116e-29 (rank : 6)
Query Neighborhood Hits	225	Target Neighborhood Hits	227	Shared Neighborhood Hits	96
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

3BP1_MOUSE
NC score	0.784461 (rank : 12)	θ value	4.16044e-13 (rank : 43)
Query Neighborhood Hits	225	Target Neighborhood Hits	238	Shared Neighborhood Hits	74
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG06_HUMAN
NC score	0.779891 (rank : 13)	θ value	1.42992e-13 (rank : 37)
Query Neighborhood Hits	225	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.777554 (rank : 14)	θ value	1.86753e-13 (rank : 40)
Query Neighborhood Hits	225	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_HUMAN
NC score	0.773710 (rank : 15)	θ value	2.60593e-15 (rank : 28)
Query Neighborhood Hits	225	Target Neighborhood Hits	376	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG01_HUMAN
NC score	0.766891 (rank : 16)	θ value	1.80466e-16 (rank : 24)
Query Neighborhood Hits	225	Target Neighborhood Hits	75	Shared Neighborhood Hits	63
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

OPHN1_HUMAN
NC score	0.764935 (rank : 17)	θ value	1.13037e-18 (rank : 13)
Query Neighborhood Hits	225	Target Neighborhood Hits	161	Shared Neighborhood Hits	68
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

GRLF1_HUMAN
NC score	0.764403 (rank : 18)	θ value	3.76295e-14 (rank : 35)
Query Neighborhood Hits	225	Target Neighborhood Hits	167	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

OPHN1_MOUSE
NC score	0.764328 (rank : 19)	θ value	1.92812e-18 (rank : 14)
Query Neighborhood Hits	225	Target Neighborhood Hits	174	Shared Neighborhood Hits	66
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG18_HUMAN
NC score	0.763814 (rank : 20)	θ value	1.86753e-13 (rank : 41)
Query Neighborhood Hits	225	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

TCGAP_MOUSE
NC score	0.762887 (rank : 21)	θ value	8.65492e-19 (rank : 12)
Query Neighborhood Hits	225	Target Neighborhood Hits	409	Shared Neighborhood Hits	77
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG18_MOUSE
NC score	0.758644 (rank : 22)	θ value	1.42992e-13 (rank : 38)
Query Neighborhood Hits	225	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_MOUSE
NC score	0.755149 (rank : 23)	θ value	1.16975e-15 (rank : 26)
Query Neighborhood Hits	225	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_HUMAN
NC score	0.748255 (rank : 24)	θ value	7.58209e-15 (rank : 30)
Query Neighborhood Hits	225	Target Neighborhood Hits	88	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG05_MOUSE
NC score	0.735033 (rank : 25)	θ value	3.76295e-14 (rank : 36)
Query Neighborhood Hits	225	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

ABR_HUMAN
NC score	0.729183 (rank : 26)	θ value	4.58923e-20 (rank : 9)
Query Neighborhood Hits	225	Target Neighborhood Hits	166	Shared Neighborhood Hits	71
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG25_MOUSE
NC score	0.725506 (rank : 27)	θ value	8.65492e-19 (rank : 11)
Query Neighborhood Hits	225	Target Neighborhood Hits	492	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG05_HUMAN
NC score	0.725443 (rank : 28)	θ value	1.86753e-13 (rank : 39)
Query Neighborhood Hits	225	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG26_HUMAN
NC score	0.721728 (rank : 29)	θ value	6.20254e-17 (rank : 23)
Query Neighborhood Hits	225	Target Neighborhood Hits	281	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

BCR_HUMAN
NC score	0.716255 (rank : 30)	θ value	1.74391e-19 (rank : 10)
Query Neighborhood Hits	225	Target Neighborhood Hits	204	Shared Neighborhood Hits	72
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG04_HUMAN
NC score	0.710346 (rank : 31)	θ value	6.20254e-17 (rank : 22)
Query Neighborhood Hits	225	Target Neighborhood Hits	307	Shared Neighborhood Hits	71
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RBP1_MOUSE
NC score	0.708018 (rank : 32)	θ value	2.43908e-13 (rank : 42)
Query Neighborhood Hits	225	Target Neighborhood Hits	493	Shared Neighborhood Hits	93
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG25_HUMAN
NC score	0.700558 (rank : 33)	θ value	7.58209e-15 (rank : 31)
Query Neighborhood Hits	225	Target Neighborhood Hits	550	Shared Neighborhood Hits	92
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRGP2_HUMAN
NC score	0.698279 (rank : 34)	θ value	2.7842e-17 (rank : 20)
Query Neighborhood Hits	225	Target Neighborhood Hits	331	Shared Neighborhood Hits	67
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RBP1_HUMAN
NC score	0.691840 (rank : 35)	θ value	5.43371e-13 (rank : 44)
Query Neighborhood Hits	225	Target Neighborhood Hits	521	Shared Neighborhood Hits	94
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP2_MOUSE
NC score	0.690785 (rank : 36)	θ value	4.74913e-17 (rank : 21)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	68
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRGP1_HUMAN
NC score	0.684420 (rank : 37)	θ value	1.52774e-15 (rank : 27)
Query Neighborhood Hits	225	Target Neighborhood Hits	390	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
NC score	0.679490 (rank : 38)	θ value	3.76295e-14 (rank : 34)
Query Neighborhood Hits	225	Target Neighborhood Hits	432	Shared Neighborhood Hits	83
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

TCGAP_HUMAN
NC score	0.677516 (rank : 39)	θ value	4.29542e-18 (rank : 18)
Query Neighborhood Hits	225	Target Neighborhood Hits	872	Shared Neighborhood Hits	91
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG07_MOUSE
NC score	0.668463 (rank : 40)	θ value	7.09661e-13 (rank : 45)
Query Neighborhood Hits	225	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.662249 (rank : 41)	θ value	1.2105e-12 (rank : 46)
Query Neighborhood Hits	225	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CE005_HUMAN
NC score	0.649800 (rank : 42)	θ value	2.20605e-14 (rank : 33)
Query Neighborhood Hits	225	Target Neighborhood Hits	213	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.647979 (rank : 43)	θ value	1.68911e-14 (rank : 32)
Query Neighborhood Hits	225	Target Neighborhood Hits	238	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

TAGAP_HUMAN
NC score	0.637069 (rank : 44)	θ value	0.00020696 (rank : 62)
Query Neighborhood Hits	225	Target Neighborhood Hits	82	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
NC score	0.633934 (rank : 45)	θ value	0.00390308 (rank : 65)
Query Neighborhood Hits	225	Target Neighborhood Hits	83	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CEND2_HUMAN
NC score	0.628173 (rank : 46)	θ value	7.58209e-15 (rank : 29)
Query Neighborhood Hits	225	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

STAR8_MOUSE
NC score	0.625705 (rank : 47)	θ value	9.59137e-10 (rank : 53)
Query Neighborhood Hits	225	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.617753 (rank : 48)	θ value	3.64472e-09 (rank : 54)
Query Neighborhood Hits	225	Target Neighborhood Hits	216	Shared Neighborhood Hits	63
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_HUMAN
NC score	0.612934 (rank : 49)	θ value	2.36244e-08 (rank : 55)
Query Neighborhood Hits	225	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
NC score	0.603612 (rank : 50)	θ value	3.08544e-08 (rank : 56)
Query Neighborhood Hits	225	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND3_MOUSE
NC score	0.586411 (rank : 51)	θ value	6.00763e-12 (rank : 47)
Query Neighborhood Hits	225	Target Neighborhood Hits	228	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.575396 (rank : 52)	θ value	2.28291e-11 (rank : 48)
Query Neighborhood Hits	225	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND1_MOUSE
NC score	0.535983 (rank : 53)	θ value	8.67504e-11 (rank : 49)
Query Neighborhood Hits	225	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

K1688_MOUSE
NC score	0.529033 (rank : 54)	θ value	0.000158464 (rank : 61)
Query Neighborhood Hits	225	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.520967 (rank : 55)	θ value	2.44474e-05 (rank : 59)
Query Neighborhood Hits	225	Target Neighborhood Hits	217	Shared Neighborhood Hits	69
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND1_HUMAN
NC score	0.515791 (rank : 56)	θ value	1.9326e-10 (rank : 51)
Query Neighborhood Hits	225	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MYO9B_MOUSE
NC score	0.442410 (rank : 57)	θ value	3.07116e-24 (rank : 8)
Query Neighborhood Hits	225	Target Neighborhood Hits	311	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.438566 (rank : 58)	θ value	9.59137e-10 (rank : 52)
Query Neighborhood Hits	225	Target Neighborhood Hits	479	Shared Neighborhood Hits	80
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

MYO9B_HUMAN
NC score	0.437986 (rank : 59)	θ value	8.08199e-25 (rank : 7)
Query Neighborhood Hits	225	Target Neighborhood Hits	641	Shared Neighborhood Hits	116
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_MOUSE
NC score	0.435001 (rank : 60)	θ value	1.47974e-10 (rank : 50)
Query Neighborhood Hits	225	Target Neighborhood Hits	435	Shared Neighborhood Hits	75
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.364019 (rank : 61)	θ value	1.43324e-05 (rank : 58)
Query Neighborhood Hits	225	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.360686 (rank : 62)	θ value	4.92598e-06 (rank : 57)
Query Neighborhood Hits	225	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85B_HUMAN
NC score	0.176944 (rank : 63)	θ value	0.000121331 (rank : 60)
Query Neighborhood Hits	225	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GRP3_HUMAN
NC score	0.162395 (rank : 64)	θ value	0.00665767 (rank : 66)
Query Neighborhood Hits	225	Target Neighborhood Hits	131	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

P85B_MOUSE
NC score	0.149719 (rank : 65)	θ value	0.000270298 (rank : 63)
Query Neighborhood Hits	225	Target Neighborhood Hits	519	Shared Neighborhood Hits	52
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

UN13B_HUMAN
NC score	0.111207 (rank : 66)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	225	Target Neighborhood Hits	217	Shared Neighborhood Hits	43
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13A_HUMAN
NC score	0.109114 (rank : 67)	θ value	1.06291 (rank : 114)
Query Neighborhood Hits	225	Target Neighborhood Hits	285	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_MOUSE
NC score	0.107463 (rank : 68)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	225	Target Neighborhood Hits	210	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PDZD8_HUMAN
NC score	0.098804 (rank : 69)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	225	Target Neighborhood Hits	185	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

P55G_HUMAN
NC score	0.098469 (rank : 70)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	225	Target Neighborhood Hits	451	Shared Neighborhood Hits	27
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
NC score	0.098038 (rank : 71)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	225	Target Neighborhood Hits	401	Shared Neighborhood Hits	28
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

RASF1_MOUSE
NC score	0.082913 (rank : 72)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	225	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

DGKQ_HUMAN
NC score	0.079616 (rank : 73)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	225	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

CENB2_HUMAN
NC score	0.078564 (rank : 74)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	225	Target Neighborhood Hits	425	Shared Neighborhood Hits	25
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

FA13A_MOUSE
NC score	0.076333 (rank : 75)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	225	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13A_HUMAN
NC score	0.075858 (rank : 76)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	225	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

VAV3_HUMAN
NC score	0.075406 (rank : 77)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	225	Target Neighborhood Hits	398	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
NC score	0.075220 (rank : 78)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	225	Target Neighborhood Hits	404	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

STAC3_MOUSE
NC score	0.074819 (rank : 79)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	225	Target Neighborhood Hits	232	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_MOUSE
NC score	0.073230 (rank : 80)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	225	Target Neighborhood Hits	268	Shared Neighborhood Hits	45
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CENB5_HUMAN
NC score	0.073229 (rank : 81)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	225	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

STAC3_HUMAN
NC score	0.072928 (rank : 82)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	225	Target Neighborhood Hits	228	Shared Neighborhood Hits	43
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CENB1_HUMAN
NC score	0.072650 (rank : 83)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	225	Target Neighborhood Hits	383	Shared Neighborhood Hits	17
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

STAC_HUMAN
NC score	0.068412 (rank : 84)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	225	Target Neighborhood Hits	276	Shared Neighborhood Hits	46
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

DGKH_HUMAN
NC score	0.068401 (rank : 85)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	225	Target Neighborhood Hits	255	Shared Neighborhood Hits	46
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

NCK2_HUMAN
NC score	0.067811 (rank : 86)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	225	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

RASF1_HUMAN
NC score	0.067455 (rank : 87)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	225	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

CIP4_HUMAN
NC score	0.067309 (rank : 88)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	225	Target Neighborhood Hits	374	Shared Neighborhood Hits	35
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

SRBS1_HUMAN
NC score	0.067174 (rank : 89)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	225	Target Neighborhood Hits	396	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

DAPP1_MOUSE
NC score	0.066991 (rank : 90)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	225	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

VAV2_MOUSE
NC score	0.066207 (rank : 91)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	225	Target Neighborhood Hits	456	Shared Neighborhood Hits	51
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV2_HUMAN
NC score	0.065904 (rank : 92)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	225	Target Neighborhood Hits	453	Shared Neighborhood Hits	51
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

DAPP1_HUMAN
NC score	0.064253 (rank : 93)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	225	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

MYO10_HUMAN
NC score	0.063991 (rank : 94)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	225	Target Neighborhood Hits	920	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

GRAP_HUMAN
NC score	0.063050 (rank : 95)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	225	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

DGKD_HUMAN
NC score	0.061519 (rank : 96)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	225	Target Neighborhood Hits	231	Shared Neighborhood Hits	47
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

GRB2_HUMAN
NC score	0.061037 (rank : 97)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	225	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.061017 (rank : 98)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	225	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRAP_MOUSE
NC score	0.060025 (rank : 99)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	225	Target Neighborhood Hits	309	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

PCTL_MOUSE
NC score	0.059833 (rank : 100)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	225	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.059158 (rank : 101)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	225	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

FA13C_HUMAN
NC score	0.059093 (rank : 102)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	225	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

TACC2_MOUSE
NC score	0.058232 (rank : 103)	θ value	0.21417 (rank : 77)
Query Neighborhood Hits	225	Target Neighborhood Hits	774	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

DDEF2_HUMAN
NC score	0.058009 (rank : 104)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	225	Target Neighborhood Hits	599	Shared Neighborhood Hits	30
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

BNIP2_HUMAN
NC score	0.057487 (rank : 105)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	225	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
NC score	0.057401 (rank : 106)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	225	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

VAV_MOUSE
NC score	0.057326 (rank : 107)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	225	Target Neighborhood Hits	430	Shared Neighborhood Hits	51
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

FA13C_MOUSE
NC score	0.057106 (rank : 108)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	225	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

DDEF2_MOUSE
NC score	0.056591 (rank : 109)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	225	Target Neighborhood Hits	625	Shared Neighborhood Hits	27
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

VINEX_MOUSE
NC score	0.056418 (rank : 110)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	225	Target Neighborhood Hits	286	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

TACC2_HUMAN
NC score	0.056283 (rank : 111)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	225	Target Neighborhood Hits	856	Shared Neighborhood Hits	57
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

VAV_HUMAN
NC score	0.056018 (rank : 112)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	225	Target Neighborhood Hits	452	Shared Neighborhood Hits	58
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ITSN1_HUMAN
NC score	0.055296 (rank : 113)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	225	Target Neighborhood Hits	1757	Shared Neighborhood Hits	98
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SRBS1_MOUSE
NC score	0.055270 (rank : 114)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	225	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ITSN1_MOUSE
NC score	0.054764 (rank : 115)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	225	Target Neighborhood Hits	1669	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ATCAY_MOUSE
NC score	0.054694 (rank : 116)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	225	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

ATCAY_HUMAN
NC score	0.054187 (rank : 117)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	225	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

PKHA1_HUMAN
NC score	0.053311 (rank : 118)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	225	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

BNIPL_MOUSE
NC score	0.053271 (rank : 119)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	225	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_HUMAN
NC score	0.053189 (rank : 120)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	225	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

DDFL1_HUMAN
NC score	0.053074 (rank : 121)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	225	Target Neighborhood Hits	353	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

VINEX_HUMAN
NC score	0.053031 (rank : 122)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	225	Target Neighborhood Hits	270	Shared Neighborhood Hits	18
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

CENA2_HUMAN
NC score	0.053026 (rank : 123)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	225	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

MYO1F_HUMAN
NC score	0.052083 (rank : 124)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	225	Target Neighborhood Hits	275	Shared Neighborhood Hits	18
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

SMP1L_HUMAN
NC score	0.052018 (rank : 125)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	225	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

MYO1F_MOUSE
NC score	0.052013 (rank : 126)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	225	Target Neighborhood Hits	262	Shared Neighborhood Hits	14
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

SMP1L_MOUSE
NC score	0.051835 (rank : 127)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	225	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMAP1_HUMAN
NC score	0.051557 (rank : 128)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	225	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

PERQ1_MOUSE
NC score	0.051467 (rank : 129)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	225	Target Neighborhood Hits	215	Shared Neighborhood Hits	17
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

DDEF1_MOUSE
NC score	0.051386 (rank : 130)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	225	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

ITSN2_HUMAN
NC score	0.050576 (rank : 131)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	225	Target Neighborhood Hits	1173	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SMAP1_MOUSE
NC score	0.050245 (rank : 132)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	225	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

RASF5_HUMAN
NC score	0.050072 (rank : 133)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	225	Target Neighborhood Hits	79	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

MY18A_HUMAN
NC score	0.048310 (rank : 134)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	225	Target Neighborhood Hits	1929	Shared Neighborhood Hits	84
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH11_HUMAN
NC score	0.048144 (rank : 135)	θ value	0.163984 (rank : 74)
Query Neighborhood Hits	225	Target Neighborhood Hits	1806	Shared Neighborhood Hits	80
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GAS7_MOUSE
NC score	0.047940 (rank : 136)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	225	Target Neighborhood Hits	259	Shared Neighborhood Hits	27
SwissProt Accessions	Q60780, Q9QY25, Q9QY26, Q9QY34	Gene names	Gas7
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

MYH11_MOUSE
NC score	0.047918 (rank : 137)	θ value	0.47712 (rank : 87)
Query Neighborhood Hits	225	Target Neighborhood Hits	1777	Shared Neighborhood Hits	79
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MRCKA_HUMAN
NC score	0.045073 (rank : 138)	θ value	0.125558 (rank : 73)
Query Neighborhood Hits	225	Target Neighborhood Hits	1999	Shared Neighborhood Hits	104
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

PI5PA_HUMAN
NC score	0.044592 (rank : 139)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	225	Target Neighborhood Hits	749	Shared Neighborhood Hits	34
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CYLN2_MOUSE
NC score	0.043409 (rank : 140)	θ value	0.00869519 (rank : 67)
Query Neighborhood Hits	225	Target Neighborhood Hits	1002	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

GAS7_HUMAN
NC score	0.042842 (rank : 141)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	225	Target Neighborhood Hits	258	Shared Neighborhood Hits	27
SwissProt Accessions	O60861, O43144	Gene names	GAS7, KIAA0394
Domain Architecture
Description	Growth-arrest-specific protein 7 (GAS-7).

MRCKB_MOUSE
NC score	0.042117 (rank : 142)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	225	Target Neighborhood Hits	2180	Shared Neighborhood Hits	107
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CCD62_HUMAN
NC score	0.041513 (rank : 143)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	225	Target Neighborhood Hits	631	Shared Neighborhood Hits	49
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

MRCKB_HUMAN
NC score	0.039729 (rank : 144)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	225	Target Neighborhood Hits	2239	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

KPCD_HUMAN
NC score	0.038990 (rank : 145)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	225	Target Neighborhood Hits	900	Shared Neighborhood Hits	47
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCE_HUMAN
NC score	0.038880 (rank : 146)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	225	Target Neighborhood Hits	906	Shared Neighborhood Hits	45
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
NC score	0.038857 (rank : 147)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	225	Target Neighborhood Hits	906	Shared Neighborhood Hits	45
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCD_MOUSE
NC score	0.038814 (rank : 148)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	225	Target Neighborhood Hits	888	Shared Neighborhood Hits	47
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

ENAH_MOUSE
NC score	0.038378 (rank : 149)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	225	Target Neighborhood Hits	919	Shared Neighborhood Hits	67
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ATX1_MOUSE
NC score	0.038358 (rank : 150)	θ value	0.0736092 (rank : 70)
Query Neighborhood Hits	225	Target Neighborhood Hits	264	Shared Neighborhood Hits	12
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CEP55_MOUSE
NC score	0.038327 (rank : 151)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	225	Target Neighborhood Hits	693	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

PCLO_HUMAN
NC score	0.038115 (rank : 152)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	225	Target Neighborhood Hits	2046	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CK5P2_HUMAN
NC score	0.037715 (rank : 153)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	225	Target Neighborhood Hits	1433	Shared Neighborhood Hits	70
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

KPCT_MOUSE
NC score	0.037677 (rank : 154)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	225	Target Neighborhood Hits	895	Shared Neighborhood Hits	46
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_HUMAN
NC score	0.037598 (rank : 155)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	225	Target Neighborhood Hits	897	Shared Neighborhood Hits	46
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

RGS3_MOUSE
NC score	0.037060 (rank : 156)	θ value	0.00228821 (rank : 64)
Query Neighborhood Hits	225	Target Neighborhood Hits	1621	Shared Neighborhood Hits	50
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

KPCB_MOUSE
NC score	0.037025 (rank : 157)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	225	Target Neighborhood Hits	1117	Shared Neighborhood Hits	49
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCL_HUMAN
NC score	0.036884 (rank : 158)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	225	Target Neighborhood Hits	887	Shared Neighborhood Hits	45
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCB_HUMAN
NC score	0.036823 (rank : 159)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	225	Target Neighborhood Hits	1121	Shared Neighborhood Hits	49
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

NIN_MOUSE
NC score	0.036816 (rank : 160)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	225	Target Neighborhood Hits	1376	Shared Neighborhood Hits	67
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

KPCL_MOUSE
NC score	0.036492 (rank : 161)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	225	Target Neighborhood Hits	891	Shared Neighborhood Hits	45
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

HOOK3_HUMAN
NC score	0.036142 (rank : 162)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	225	Target Neighborhood Hits	1070	Shared Neighborhood Hits	63
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

KPCG_MOUSE
NC score	0.035311 (rank : 163)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	225	Target Neighborhood Hits	1123	Shared Neighborhood Hits	48
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

GOGB1_HUMAN
NC score	0.035305 (rank : 164)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	225	Target Neighborhood Hits	2297	Shared Neighborhood Hits	85
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HMMR_MOUSE
NC score	0.035291 (rank : 165)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	225	Target Neighborhood Hits	1178	Shared Neighborhood Hits	66
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CCHCR_HUMAN
NC score	0.035265 (rank : 166)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	225	Target Neighborhood Hits	717	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

KPCG_HUMAN
NC score	0.035216 (rank : 167)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	225	Target Neighborhood Hits	1126	Shared Neighborhood Hits	48
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MRIP_HUMAN
NC score	0.035099 (rank : 168)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	225	Target Neighborhood Hits	578	Shared Neighborhood Hits	51
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

KPCD3_HUMAN
NC score	0.034998 (rank : 169)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	225	Target Neighborhood Hits	895	Shared Neighborhood Hits	47
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

KPCA_HUMAN
NC score	0.034739 (rank : 170)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	225	Target Neighborhood Hits	1070	Shared Neighborhood Hits	50
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCD1_HUMAN
NC score	0.034440 (rank : 171)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	225	Target Neighborhood Hits	901	Shared Neighborhood Hits	47
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD3_MOUSE
NC score	0.034288 (rank : 172)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	225	Target Neighborhood Hits	901	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

SPTN5_HUMAN
NC score	0.034100 (rank : 173)	θ value	0.0961366 (rank : 71)
Query Neighborhood Hits	225	Target Neighborhood Hits	674	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

KPCA_MOUSE
NC score	0.034008 (rank : 174)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	225	Target Neighborhood Hits	1067	Shared Neighborhood Hits	50
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCD1_MOUSE
NC score	0.033838 (rank : 175)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	225	Target Neighborhood Hits	891	Shared Neighborhood Hits	49
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

TRAK1_HUMAN
NC score	0.033179 (rank : 176)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	225	Target Neighborhood Hits	660	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

CCHCR_MOUSE
NC score	0.033077 (rank : 177)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	225	Target Neighborhood Hits	932	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

KPCD2_HUMAN
NC score	0.032898 (rank : 178)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	225	Target Neighborhood Hits	910	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

TXLNA_HUMAN
NC score	0.032392 (rank : 179)	θ value	0.0961366 (rank : 72)
Query Neighborhood Hits	225	Target Neighborhood Hits	982	Shared Neighborhood Hits	53
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

HOOK3_MOUSE
NC score	0.031965 (rank : 180)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	225	Target Neighborhood Hits	1007	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

NDE1_HUMAN
NC score	0.031446 (rank : 181)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	225	Target Neighborhood Hits	823	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

KPCI_MOUSE
NC score	0.030907 (rank : 182)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	225	Target Neighborhood Hits	888	Shared Neighborhood Hits	47
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

KPCI_HUMAN
NC score	0.030766 (rank : 183)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	225	Target Neighborhood Hits	885	Shared Neighborhood Hits	47
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

LRSM1_HUMAN
NC score	0.030212 (rank : 184)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	225	Target Neighborhood Hits	1078	Shared Neighborhood Hits	57
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

GOGA5_MOUSE
NC score	0.030049 (rank : 185)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	225	Target Neighborhood Hits	1434	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

OPTN_MOUSE
NC score	0.029842 (rank : 186)	θ value	0.47712 (rank : 88)
Query Neighborhood Hits	225	Target Neighborhood Hits	1120	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CENPE_HUMAN
NC score	0.029727 (rank : 187)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	225	Target Neighborhood Hits	2060	Shared Neighborhood Hits	81
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

G45IP_MOUSE
NC score	0.029367 (rank : 188)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	225	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

SELPL_MOUSE
NC score	0.029314 (rank : 189)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	225	Target Neighborhood Hits	588	Shared Neighborhood Hits	27
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

STX12_MOUSE
NC score	0.028722 (rank : 190)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	225	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

U2AFM_MOUSE
NC score	0.028640 (rank : 191)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	225	Target Neighborhood Hits	543	Shared Neighborhood Hits	42
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

CSPG5_HUMAN
NC score	0.028003 (rank : 192)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	225	Target Neighborhood Hits	199	Shared Neighborhood Hits	11
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

SMOO_HUMAN
NC score	0.027761 (rank : 193)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	225	Target Neighborhood Hits	391	Shared Neighborhood Hits	23
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

MDC1_HUMAN
NC score	0.026119 (rank : 194)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	225	Target Neighborhood Hits	1446	Shared Neighborhood Hits	53
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NUMA1_HUMAN
NC score	0.025940 (rank : 195)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	225	Target Neighborhood Hits	1523	Shared Neighborhood Hits	67
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CNTRB_MOUSE
NC score	0.025889 (rank : 196)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	225	Target Neighborhood Hits	1029	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

MBB1A_HUMAN
NC score	0.025511 (rank : 197)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	225	Target Neighborhood Hits	665	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

RERE_MOUSE
NC score	0.025243 (rank : 198)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	225	Target Neighborhood Hits	785	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RASF7_HUMAN
NC score	0.025188 (rank : 199)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	225	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

MEF2C_HUMAN
NC score	0.024817 (rank : 200)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	225	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

MAGE1_HUMAN
NC score	0.024746 (rank : 201)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	225	Target Neighborhood Hits	1389	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PPIP2_MOUSE
NC score	0.024704 (rank : 202)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	225	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

MEF2C_MOUSE
NC score	0.024473 (rank : 203)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	225	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20	Gene names	Mef2c
Domain Architecture	No domain graphic available
Description	Myocyte-specific enhancer factor 2C.

ANR26_MOUSE
NC score	0.023847 (rank : 204)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	225	Target Neighborhood Hits	1554	Shared Neighborhood Hits	71
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CIC_HUMAN
NC score	0.023131 (rank : 205)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	225	Target Neighborhood Hits	992	Shared Neighborhood Hits	40
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

IQEC3_MOUSE
NC score	0.022936 (rank : 206)	θ value	0.0330416 (rank : 68)
Query Neighborhood Hits	225	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

LRSM1_MOUSE
NC score	0.022873 (rank : 207)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	225	Target Neighborhood Hits	874	Shared Neighborhood Hits	45
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MEIS2_MOUSE
NC score	0.022338 (rank : 208)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	225	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

MEIS2_HUMAN
NC score	0.022158 (rank : 209)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	225	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	O14770, Q96KI4, Q96KI5, Q9NRS1, Q9NRS2, Q9NRS3	Gene names	MEIS2, MRG1
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

MACF1_MOUSE
NC score	0.021783 (rank : 210)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	225	Target Neighborhood Hits	1313	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

KSR2_HUMAN
NC score	0.021409 (rank : 211)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	225	Target Neighborhood Hits	920	Shared Neighborhood Hits	47
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

NCOA6_HUMAN
NC score	0.021028 (rank : 212)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	225	Target Neighborhood Hits	1202	Shared Neighborhood Hits	46
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

KIF5C_MOUSE
NC score	0.020969 (rank : 213)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	225	Target Neighborhood Hits	1040	Shared Neighborhood Hits	62
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KSR1_MOUSE
NC score	0.020918 (rank : 214)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	225	Target Neighborhood Hits	870	Shared Neighborhood Hits	39
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

GLE1_MOUSE
NC score	0.020830 (rank : 215)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	225	Target Neighborhood Hits	504	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

3BP5_MOUSE
NC score	0.020806 (rank : 216)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	225	Target Neighborhood Hits	346	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

TTLL5_HUMAN
NC score	0.020536 (rank : 217)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	225	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

CAR10_HUMAN
NC score	0.020469 (rank : 218)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	225	Target Neighborhood Hits	569	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

AMZ1_MOUSE
NC score	0.020461 (rank : 219)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	225	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVF9, Q811F9, Q8BMM5	Gene names	Amz1
Domain Architecture	No domain graphic available
Description	Archaemetzincin-1 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 1).

IFT81_MOUSE
NC score	0.020408 (rank : 220)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	225	Target Neighborhood Hits	959	Shared Neighborhood Hits	52
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

CCD91_MOUSE
NC score	0.020380 (rank : 221)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	225	Target Neighborhood Hits	699	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

KIF5C_HUMAN
NC score	0.020242 (rank : 222)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	225	Target Neighborhood Hits	974	Shared Neighborhood Hits	62
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KSR1_HUMAN
NC score	0.020146 (rank : 223)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	225	Target Neighborhood Hits	867	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

BCL9_MOUSE
NC score	0.020130 (rank : 224)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	225	Target Neighborhood Hits	770	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MD1L1_MOUSE
NC score	0.019633 (rank : 225)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	225	Target Neighborhood Hits	1001	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

DMP1_MOUSE
NC score	0.019617 (rank : 226)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	225	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

3BP5_HUMAN
NC score	0.019560 (rank : 227)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	225	Target Neighborhood Hits	375	Shared Neighborhood Hits	27
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

SEN54_HUMAN
NC score	0.019199 (rank : 228)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	225	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

KIF5A_HUMAN
NC score	0.019040 (rank : 229)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	225	Target Neighborhood Hits	843	Shared Neighborhood Hits	50
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

NU214_HUMAN
NC score	0.019013 (rank : 230)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	225	Target Neighborhood Hits	657	Shared Neighborhood Hits	36
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

KIF5A_MOUSE
NC score	0.018653 (rank : 231)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	225	Target Neighborhood Hits	859	Shared Neighborhood Hits	51
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

ZIMP7_MOUSE
NC score	0.018424 (rank : 232)	θ value	0.62314 (rank : 95)
Query Neighborhood Hits	225	Target Neighborhood Hits	566	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ATX7_HUMAN
NC score	0.017123 (rank : 233)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	225	Target Neighborhood Hits	351	Shared Neighborhood Hits	17
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

LRC49_HUMAN
NC score	0.016856 (rank : 234)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	225	Target Neighborhood Hits	210	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUZ0, Q9NXM6	Gene names	LRRC49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4).

IDLC_HUMAN
NC score	0.016486 (rank : 235)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	225	Target Neighborhood Hits	348	Shared Neighborhood Hits	26
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

VIME_MOUSE
NC score	0.016359 (rank : 236)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	225	Target Neighborhood Hits	716	Shared Neighborhood Hits	54
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

MLL3_HUMAN
NC score	0.016131 (rank : 237)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	225	Target Neighborhood Hits	1644	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

VIME_HUMAN
NC score	0.015739 (rank : 238)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	225	Target Neighborhood Hits	706	Shared Neighborhood Hits	52
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

IDLC_MOUSE
NC score	0.015727 (rank : 239)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	225	Target Neighborhood Hits	321	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

SSBP4_HUMAN
NC score	0.015615 (rank : 240)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	225	Target Neighborhood Hits	753	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

IRX5_HUMAN
NC score	0.015007 (rank : 241)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	225	Target Neighborhood Hits	362	Shared Neighborhood Hits	17
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

IRX5_MOUSE
NC score	0.014771 (rank : 242)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

SLK_MOUSE
NC score	0.014337 (rank : 243)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	225	Target Neighborhood Hits	1798	Shared Neighborhood Hits	91
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

EP300_HUMAN
NC score	0.014171 (rank : 244)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	225	Target Neighborhood Hits	821	Shared Neighborhood Hits	34
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CSKI2_HUMAN
NC score	0.014125 (rank : 245)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	225	Target Neighborhood Hits	747	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ZDHC1_HUMAN
NC score	0.014118 (rank : 246)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	225	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

PO3F4_HUMAN
NC score	0.013543 (rank : 247)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	225	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

PLXB1_HUMAN
NC score	0.013453 (rank : 248)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	225	Target Neighborhood Hits	360	Shared Neighborhood Hits	20
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

CASB_MOUSE
NC score	0.012115 (rank : 249)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	225	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P10598, Q543D9, Q8VCT6, Q8VCU8, Q91VI5, Q922Y5, Q9D1U6, Q9D1U7	Gene names	Csn2, Csnb
Domain Architecture
Description	Beta-casein precursor.

DGCR8_HUMAN
NC score	0.011895 (rank : 250)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	225	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

B4GT1_HUMAN
NC score	0.011598 (rank : 251)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	225	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

LR37B_HUMAN
NC score	0.011483 (rank : 252)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	225	Target Neighborhood Hits	392	Shared Neighborhood Hits	14
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

RARG1_HUMAN
NC score	0.011245 (rank : 253)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	225	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_HUMAN
NC score	0.011171 (rank : 254)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	225	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

TMUB2_MOUSE
NC score	0.011068 (rank : 255)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	225	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q3V209, Q8K0X0, Q91YQ0, Q9D8C5	Gene names	Tmub2
Domain Architecture	No domain graphic available
Description	Transmembrane and ubiquitin-like domain-containing protein 2.

ZCHC6_HUMAN
NC score	0.010880 (rank : 256)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	225	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

DVL3_HUMAN
NC score	0.010706 (rank : 257)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	225	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

PO3F4_MOUSE
NC score	0.010631 (rank : 258)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	225	Target Neighborhood Hits	281	Shared Neighborhood Hits	5
SwissProt Accessions	P62515, P25216	Gene names	Pou3f4, Brn-4, Brn4, Otf9
Domain Architecture	No domain graphic available
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

F10A5_HUMAN
NC score	0.010289 (rank : 259)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	225	Target Neighborhood Hits	277	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

TEX14_MOUSE
NC score	0.009845 (rank : 260)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	225	Target Neighborhood Hits	1333	Shared Neighborhood Hits	56
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRIP6_HUMAN
NC score	0.009712 (rank : 261)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	225	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

RARG1_MOUSE
NC score	0.009669 (rank : 262)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	225	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
NC score	0.009580 (rank : 263)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	225	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

SEH1L_HUMAN
NC score	0.009123 (rank : 264)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	225	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EE3, Q8NFU6, Q96MH3, Q9C069	Gene names	SEH1L, SEC13L, SEH1
Domain Architecture
Description	Nucleoporin SEH1-like (SEC13-like protein).

RFX1_HUMAN
NC score	0.008785 (rank : 265)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	225	Target Neighborhood Hits	256	Shared Neighborhood Hits	19
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

BTBD7_HUMAN
NC score	0.008505 (rank : 266)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	225	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

PAK4_MOUSE
NC score	0.008277 (rank : 267)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	225	Target Neighborhood Hits	1098	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

MK07_HUMAN
NC score	0.006835 (rank : 268)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	225	Target Neighborhood Hits	1087	Shared Neighborhood Hits	50
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

COKA1_HUMAN
NC score	0.004410 (rank : 269)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	225	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

NRCAM_HUMAN
NC score	0.004342 (rank : 270)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	225	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
NC score	0.004322 (rank : 271)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	225	Target Neighborhood Hits	432	Shared Neighborhood Hits	6
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

UBP24_HUMAN
NC score	0.004074 (rank : 272)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	225	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

ADA12_MOUSE
NC score	0.002235 (rank : 273)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	225	Target Neighborhood Hits	474	Shared Neighborhood Hits	16
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

HXB3_HUMAN
NC score	0.001633 (rank : 274)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	225	Target Neighborhood Hits	559	Shared Neighborhood Hits	17
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

ZN447_HUMAN
NC score	0.001468 (rank : 275)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	225	Target Neighborhood Hits	899	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

DDX51_HUMAN
NC score	0.001209 (rank : 276)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	225	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

CP46A_MOUSE
NC score	0.000657 (rank : 277)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	225	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVK8	Gene names	Cyp46a1, Cyp46
Domain Architecture
Description	Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol 24-hydroxylase) (CH24H).

ROBO3_MOUSE
NC score	0.000382 (rank : 278)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	225	Target Neighborhood Hits	524	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

STRN4_MOUSE
NC score	-0.000005 (rank : 279)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	225	Target Neighborhood Hits	324	Shared Neighborhood Hits	3
SwissProt Accessions	P58404, Q68EF5	Gene names	Strn4, Zin
Domain Architecture
Description	Striatin-4 (Zinedin).

NOTC2_HUMAN
NC score	-0.000602 (rank : 280)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	225	Target Neighborhood Hits	1113	Shared Neighborhood Hits	20
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PCDB4_HUMAN
NC score	-0.002214 (rank : 281)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	225	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5E5	Gene names	PCDHB4
Domain Architecture
Description	Protocadherin beta 4 precursor (PCDH-beta4).

SALL1_MOUSE
NC score	-0.003020 (rank : 282)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	225	Target Neighborhood Hits	826	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

ZN232_HUMAN
NC score	-0.005843 (rank : 283)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	225	Target Neighborhood Hits	754	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).

ZN662_HUMAN
NC score	-0.006041 (rank : 284)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	225	Target Neighborhood Hits	738	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZS27, Q6ZNF8, Q6ZQW8	Gene names	ZNF662
Domain Architecture	No domain graphic available
Description	Zinc finger protein 662.