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Network neighborhood for query Sequence : K1688_MOUSE

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K1688_MOUSE
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

K1688_HUMAN
θ value	0 (rank : 1)	NC score	0.963138 (rank : 2)
Query Neighborhood Hits	188	Target Neighborhood Hits	217	Shared Neighborhood Hits	115
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K1688_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	188	Target Neighborhood Hits	188	Shared Neighborhood Hits	188
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

RHG25_MOUSE
θ value	8.10077e-17 (rank : 3)	NC score	0.599324 (rank : 3)
Query Neighborhood Hits	188	Target Neighborhood Hits	492	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
θ value	3.07829e-16 (rank : 4)	NC score	0.586865 (rank : 8)
Query Neighborhood Hits	188	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG18_HUMAN
θ value	1.133e-10 (rank : 5)	NC score	0.593796 (rank : 5)
Query Neighborhood Hits	188	Target Neighborhood Hits	90	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
θ value	1.47974e-10 (rank : 6)	NC score	0.593873 (rank : 4)
Query Neighborhood Hits	188	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_MOUSE
θ value	4.30538e-10 (rank : 7)	NC score	0.590182 (rank : 7)
Query Neighborhood Hits	188	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

MYO15_HUMAN
θ value	1.63604e-09 (rank : 8)	NC score	0.153897 (rank : 63)
Query Neighborhood Hits	188	Target Neighborhood Hits	671	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

TCGAP_HUMAN
θ value	2.13673e-09 (rank : 9)	NC score	0.497836 (rank : 30)
Query Neighborhood Hits	188	Target Neighborhood Hits	872	Shared Neighborhood Hits	103
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG08_HUMAN
θ value	3.64472e-09 (rank : 10)	NC score	0.582431 (rank : 9)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

MYO9B_HUMAN
θ value	4.76016e-09 (rank : 11)	NC score	0.347594 (rank : 52)
Query Neighborhood Hits	188	Target Neighborhood Hits	641	Shared Neighborhood Hits	86
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TCGAP_MOUSE
θ value	6.21693e-09 (rank : 12)	NC score	0.543275 (rank : 16)
Query Neighborhood Hits	188	Target Neighborhood Hits	409	Shared Neighborhood Hits	77
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MYO7A_MOUSE
θ value	8.11959e-09 (rank : 13)	NC score	0.142230 (rank : 65)
Query Neighborhood Hits	188	Target Neighborhood Hits	235	Shared Neighborhood Hits	10
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CE005_HUMAN
θ value	1.38499e-08 (rank : 14)	NC score	0.486452 (rank : 39)
Query Neighborhood Hits	188	Target Neighborhood Hits	213	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

SRGP2_HUMAN
θ value	1.38499e-08 (rank : 15)	NC score	0.511750 (rank : 25)
Query Neighborhood Hits	188	Target Neighborhood Hits	331	Shared Neighborhood Hits	68
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

3BP1_MOUSE
θ value	1.80886e-08 (rank : 16)	NC score	0.593394 (rank : 6)
Query Neighborhood Hits	188	Target Neighborhood Hits	238	Shared Neighborhood Hits	77
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

MYO9B_MOUSE
θ value	1.80886e-08 (rank : 17)	NC score	0.347421 (rank : 53)
Query Neighborhood Hits	188	Target Neighborhood Hits	311	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SRGP2_MOUSE
θ value	1.80886e-08 (rank : 18)	NC score	0.507828 (rank : 26)
Query Neighborhood Hits	188	Target Neighborhood Hits	324	Shared Neighborhood Hits	66
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG01_HUMAN
θ value	3.08544e-08 (rank : 19)	NC score	0.581897 (rank : 10)
Query Neighborhood Hits	188	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

3BP1_HUMAN
θ value	4.0297e-08 (rank : 20)	NC score	0.569561 (rank : 11)
Query Neighborhood Hits	188	Target Neighborhood Hits	376	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CE005_MOUSE
θ value	8.97725e-08 (rank : 21)	NC score	0.479284 (rank : 42)
Query Neighborhood Hits	188	Target Neighborhood Hits	238	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

MYO7A_HUMAN
θ value	1.17247e-07 (rank : 22)	NC score	0.138634 (rank : 66)
Query Neighborhood Hits	188	Target Neighborhood Hits	209	Shared Neighborhood Hits	10
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO15_MOUSE
θ value	1.53129e-07 (rank : 23)	NC score	0.151261 (rank : 64)
Query Neighborhood Hits	188	Target Neighborhood Hits	467	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RBP1_MOUSE
θ value	1.53129e-07 (rank : 24)	NC score	0.505666 (rank : 28)
Query Neighborhood Hits	188	Target Neighborhood Hits	493	Shared Neighborhood Hits	62
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_MOUSE
θ value	1.53129e-07 (rank : 25)	NC score	0.555543 (rank : 13)
Query Neighborhood Hits	188	Target Neighborhood Hits	185	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

BCR_HUMAN
θ value	2.61198e-07 (rank : 26)	NC score	0.484493 (rank : 41)
Query Neighborhood Hits	188	Target Neighborhood Hits	204	Shared Neighborhood Hits	61
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CHIN_MOUSE
θ value	3.41135e-07 (rank : 27)	NC score	0.496545 (rank : 32)
Query Neighborhood Hits	188	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

FNBP2_HUMAN
θ value	3.41135e-07 (rank : 28)	NC score	0.494910 (rank : 33)
Query Neighborhood Hits	188	Target Neighborhood Hits	432	Shared Neighborhood Hits	70
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RBP1_HUMAN
θ value	7.59969e-07 (rank : 29)	NC score	0.485800 (rank : 40)
Query Neighborhood Hits	188	Target Neighborhood Hits	521	Shared Neighborhood Hits	61
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG04_HUMAN
θ value	7.59969e-07 (rank : 30)	NC score	0.507501 (rank : 27)
Query Neighborhood Hits	188	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SRGP1_HUMAN
θ value	7.59969e-07 (rank : 31)	NC score	0.492864 (rank : 34)
Query Neighborhood Hits	188	Target Neighborhood Hits	390	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

TAGAP_HUMAN
θ value	9.92553e-07 (rank : 32)	NC score	0.532817 (rank : 21)
Query Neighborhood Hits	188	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
θ value	1.29631e-06 (rank : 33)	NC score	0.534459 (rank : 20)
Query Neighborhood Hits	188	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CHIN_HUMAN
θ value	1.69304e-06 (rank : 34)	NC score	0.490345 (rank : 36)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG06_MOUSE
θ value	2.88788e-06 (rank : 35)	NC score	0.556398 (rank : 12)
Query Neighborhood Hits	188	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RGAP1_HUMAN
θ value	3.77169e-06 (rank : 36)	NC score	0.546844 (rank : 15)
Query Neighborhood Hits	188	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG12_HUMAN
θ value	3.77169e-06 (rank : 37)	NC score	0.537178 (rank : 18)
Query Neighborhood Hits	188	Target Neighborhood Hits	190	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	3.77169e-06 (rank : 38)	NC score	0.538222 (rank : 17)
Query Neighborhood Hits	188	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CHIO_MOUSE
θ value	4.92598e-06 (rank : 39)	NC score	0.511850 (rank : 24)
Query Neighborhood Hits	188	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG06_HUMAN
θ value	8.40245e-06 (rank : 40)	NC score	0.555386 (rank : 14)
Query Neighborhood Hits	188	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CHIO_HUMAN
θ value	1.09739e-05 (rank : 41)	NC score	0.488261 (rank : 37)
Query Neighborhood Hits	188	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

OPHN1_HUMAN
θ value	1.09739e-05 (rank : 42)	NC score	0.501570 (rank : 29)
Query Neighborhood Hits	188	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

ABR_HUMAN
θ value	1.43324e-05 (rank : 43)	NC score	0.486501 (rank : 38)
Query Neighborhood Hits	188	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

I5P2_HUMAN
θ value	1.43324e-05 (rank : 44)	NC score	0.321949 (rank : 55)
Query Neighborhood Hits	188	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OPHN1_MOUSE
θ value	2.44474e-05 (rank : 45)	NC score	0.497552 (rank : 31)
Query Neighborhood Hits	188	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OCRL_HUMAN
θ value	0.000121331 (rank : 46)	NC score	0.304116 (rank : 58)
Query Neighborhood Hits	188	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

GMIP_HUMAN
θ value	0.000158464 (rank : 47)	NC score	0.529033 (rank : 22)
Query Neighborhood Hits	188	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GRLF1_HUMAN
θ value	0.000158464 (rank : 48)	NC score	0.492234 (rank : 35)
Query Neighborhood Hits	188	Target Neighborhood Hits	167	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG07_MOUSE
θ value	0.00020696 (rank : 49)	NC score	0.451762 (rank : 45)
Query Neighborhood Hits	188	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

SRRM2_HUMAN
θ value	0.00020696 (rank : 50)	NC score	0.099510 (rank : 73)
Query Neighborhood Hits	188	Target Neighborhood Hits	1296	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RHG09_HUMAN
θ value	0.000461057 (rank : 51)	NC score	0.536518 (rank : 19)
Query Neighborhood Hits	188	Target Neighborhood Hits	186	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

GMIP_MOUSE
θ value	0.000602161 (rank : 52)	NC score	0.522201 (rank : 23)
Query Neighborhood Hits	188	Target Neighborhood Hits	202	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG07_HUMAN
θ value	0.000602161 (rank : 53)	NC score	0.444921 (rank : 46)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	59
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

MYO10_HUMAN
θ value	0.00134147 (rank : 54)	NC score	0.115817 (rank : 67)
Query Neighborhood Hits	188	Target Neighborhood Hits	920	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

RHG26_HUMAN
θ value	0.00228821 (rank : 55)	NC score	0.460360 (rank : 43)
Query Neighborhood Hits	188	Target Neighborhood Hits	281	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

STA13_HUMAN
θ value	0.00390308 (rank : 56)	NC score	0.408370 (rank : 48)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

RHG05_MOUSE
θ value	0.00665767 (rank : 57)	NC score	0.458239 (rank : 44)
Query Neighborhood Hits	188	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

ARI1B_HUMAN
θ value	0.00869519 (rank : 58)	NC score	0.086989 (rank : 79)
Query Neighborhood Hits	188	Target Neighborhood Hits	567	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ATX7_HUMAN
θ value	0.0113563 (rank : 59)	NC score	0.105058 (rank : 70)
Query Neighborhood Hits	188	Target Neighborhood Hits	351	Shared Neighborhood Hits	32
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

UBN1_HUMAN
θ value	0.0113563 (rank : 60)	NC score	0.080920 (rank : 92)
Query Neighborhood Hits	188	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

ATX7_MOUSE
θ value	0.0193708 (rank : 61)	NC score	0.101248 (rank : 72)
Query Neighborhood Hits	188	Target Neighborhood Hits	328	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

IASPP_MOUSE
θ value	0.0330416 (rank : 62)	NC score	0.064255 (rank : 116)
Query Neighborhood Hits	188	Target Neighborhood Hits	1024	Shared Neighborhood Hits	62
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

RGS3_HUMAN
θ value	0.0330416 (rank : 63)	NC score	0.059133 (rank : 120)
Query Neighborhood Hits	188	Target Neighborhood Hits	1375	Shared Neighborhood Hits	70
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

STA13_MOUSE
θ value	0.0736092 (rank : 64)	NC score	0.392066 (rank : 51)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

BCAR1_HUMAN
θ value	0.0961366 (rank : 65)	NC score	0.072710 (rank : 98)
Query Neighborhood Hits	188	Target Neighborhood Hits	554	Shared Neighborhood Hits	56
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MILK2_HUMAN
θ value	0.0961366 (rank : 66)	NC score	0.038077 (rank : 179)
Query Neighborhood Hits	188	Target Neighborhood Hits	457	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MINT_MOUSE
θ value	0.0961366 (rank : 67)	NC score	0.046893 (rank : 170)
Query Neighborhood Hits	188	Target Neighborhood Hits	1514	Shared Neighborhood Hits	58
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

STAR8_MOUSE
θ value	0.0961366 (rank : 68)	NC score	0.402713 (rank : 49)
Query Neighborhood Hits	188	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RERE_MOUSE
θ value	0.163984 (rank : 69)	NC score	0.082272 (rank : 83)
Query Neighborhood Hits	188	Target Neighborhood Hits	785	Shared Neighborhood Hits	49
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SRRM2_MOUSE
θ value	0.163984 (rank : 70)	NC score	0.097011 (rank : 74)
Query Neighborhood Hits	188	Target Neighborhood Hits	1470	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STAR8_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.397043 (rank : 50)
Query Neighborhood Hits	188	Target Neighborhood Hits	216	Shared Neighborhood Hits	66
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

GAK5_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.071979 (rank : 100)
Query Neighborhood Hits	188	Target Neighborhood Hits	429	Shared Neighborhood Hits	44
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.072056 (rank : 99)
Query Neighborhood Hits	188	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LAP4_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.017316 (rank : 208)
Query Neighborhood Hits	188	Target Neighborhood Hits	608	Shared Neighborhood Hits	16
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

RERE_HUMAN
θ value	0.21417 (rank : 75)	NC score	0.082494 (rank : 82)
Query Neighborhood Hits	188	Target Neighborhood Hits	779	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

ARI1A_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.086877 (rank : 80)
Query Neighborhood Hits	188	Target Neighborhood Hits	787	Shared Neighborhood Hits	62
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

R51A1_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.047918 (rank : 169)
Query Neighborhood Hits	188	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

SMYD4_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.044856 (rank : 171)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

WBP4_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.089112 (rank : 77)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

CEND3_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.308949 (rank : 56)
Query Neighborhood Hits	188	Target Neighborhood Hits	275	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

GAK11_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.071284 (rank : 102)
Query Neighborhood Hits	188	Target Neighborhood Hits	409	Shared Neighborhood Hits	44
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.068401 (rank : 109)
Query Neighborhood Hits	188	Target Neighborhood Hits	374	Shared Neighborhood Hits	38
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	0.365318 (rank : 83)	NC score	0.071041 (rank : 103)
Query Neighborhood Hits	188	Target Neighborhood Hits	406	Shared Neighborhood Hits	43
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	0.365318 (rank : 84)	NC score	0.071353 (rank : 101)
Query Neighborhood Hits	188	Target Neighborhood Hits	415	Shared Neighborhood Hits	44
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HGS_MOUSE
θ value	0.365318 (rank : 85)	NC score	0.030974 (rank : 189)
Query Neighborhood Hits	188	Target Neighborhood Hits	589	Shared Neighborhood Hits	33
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

NOS2A_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.020633 (rank : 204)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

SRRM1_MOUSE
θ value	0.47712 (rank : 87)	NC score	0.109674 (rank : 69)
Query Neighborhood Hits	188	Target Neighborhood Hits	966	Shared Neighborhood Hits	70
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM1_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.103907 (rank : 71)
Query Neighborhood Hits	188	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

GAK1_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.064685 (rank : 114)
Query Neighborhood Hits	188	Target Neighborhood Hits	268	Shared Neighborhood Hits	30
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RHG05_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.431187 (rank : 47)
Query Neighborhood Hits	188	Target Neighborhood Hits	158	Shared Neighborhood Hits	63
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

BCAR1_MOUSE
θ value	1.06291 (rank : 91)	NC score	0.075684 (rank : 95)
Query Neighborhood Hits	188	Target Neighborhood Hits	438	Shared Neighborhood Hits	51
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CK024_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.039783 (rank : 175)
Query Neighborhood Hits	188	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

ECM1_HUMAN
θ value	1.06291 (rank : 93)	NC score	0.041517 (rank : 174)
Query Neighborhood Hits	188	Target Neighborhood Hits	182	Shared Neighborhood Hits	24
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

GAK3_HUMAN
θ value	1.06291 (rank : 94)	NC score	0.062970 (rank : 118)
Query Neighborhood Hits	188	Target Neighborhood Hits	182	Shared Neighborhood Hits	23
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SREC2_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.010775 (rank : 225)
Query Neighborhood Hits	188	Target Neighborhood Hits	605	Shared Neighborhood Hits	20
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ZCPW1_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.029390 (rank : 191)
Query Neighborhood Hits	188	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

CABYR_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.031603 (rank : 187)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

GMCL1_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.015604 (rank : 212)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q920G9, Q9DBW5, Q9QUP6	Gene names	Gmcl1, Gcl, Gcl1
Domain Architecture
Description	Germ cell-less protein-like 1 (mGcl-1) (DP-interacting protein) (DIP).

SPN90_MOUSE
θ value	1.38821 (rank : 99)	NC score	0.034404 (rank : 183)
Query Neighborhood Hits	188	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

ZN509_HUMAN
θ value	1.38821 (rank : 100)	NC score	-0.003512 (rank : 251)
Query Neighborhood Hits	188	Target Neighborhood Hits	846	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZSB9, Q59FJ4, Q5EBN0, Q8TB80	Gene names	ZNF509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

CIP4_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.069188 (rank : 107)
Query Neighborhood Hits	188	Target Neighborhood Hits	374	Shared Neighborhood Hits	12
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

MK07_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.002156 (rank : 245)
Query Neighborhood Hits	188	Target Neighborhood Hits	1087	Shared Neighborhood Hits	25
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

PQBP1_MOUSE
θ value	1.81305 (rank : 103)	NC score	0.065940 (rank : 113)
Query Neighborhood Hits	188	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

SAPS1_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.042558 (rank : 173)
Query Neighborhood Hits	188	Target Neighborhood Hits	704	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

VINEX_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.051416 (rank : 158)
Query Neighborhood Hits	188	Target Neighborhood Hits	286	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

EP400_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.030174 (rank : 190)
Query Neighborhood Hits	188	Target Neighborhood Hits	592	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

KKCC2_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.000918 (rank : 247)
Query Neighborhood Hits	188	Target Neighborhood Hits	852	Shared Neighborhood Hits	10
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

LAP4_MOUSE
θ value	2.36792 (rank : 108)	NC score	0.014753 (rank : 214)
Query Neighborhood Hits	188	Target Neighborhood Hits	590	Shared Neighborhood Hits	16
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MDC1_HUMAN
θ value	2.36792 (rank : 109)	NC score	0.063972 (rank : 117)
Query Neighborhood Hits	188	Target Neighborhood Hits	1446	Shared Neighborhood Hits	72
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PKHA1_HUMAN
θ value	2.36792 (rank : 110)	NC score	0.058626 (rank : 121)
Query Neighborhood Hits	188	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.054349 (rank : 144)
Query Neighborhood Hits	188	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PQBP1_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.064420 (rank : 115)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

PRB4S_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.073123 (rank : 97)
Query Neighborhood Hits	188	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SOAT2_HUMAN
θ value	2.36792 (rank : 114)	NC score	0.016951 (rank : 211)
Query Neighborhood Hits	188	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O75908, Q96TD4, Q9UNR2	Gene names	SOAT2, ACACT2, ACAT2
Domain Architecture
Description	Sterol O-acyltransferase 2 (EC 2.3.1.26) (Cholesterol acyltransferase 2) (Acyl coenzyme A:cholesterol acyltransferase 2) (ACAT-2).

SYGP1_HUMAN
θ value	2.36792 (rank : 115)	NC score	0.022811 (rank : 200)
Query Neighborhood Hits	188	Target Neighborhood Hits	589	Shared Neighborhood Hits	14
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

TOB1_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.027296 (rank : 194)
Query Neighborhood Hits	188	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q61471	Gene names	Tob1, Tob, Trob
Domain Architecture
Description	Tob1 protein (Transducer of erbB-2 1).

UBP2L_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.027818 (rank : 192)
Query Neighborhood Hits	188	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

ATX2_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.031112 (rank : 188)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	35
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CEND3_MOUSE
θ value	3.0926 (rank : 119)	NC score	0.306359 (rank : 57)
Query Neighborhood Hits	188	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CUTL2_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.013858 (rank : 217)
Query Neighborhood Hits	188	Target Neighborhood Hits	906	Shared Neighborhood Hits	23
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

PPRB_MOUSE
θ value	3.0926 (rank : 121)	NC score	0.038904 (rank : 176)
Query Neighborhood Hits	188	Target Neighborhood Hits	354	Shared Neighborhood Hits	25
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRP2_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.111958 (rank : 68)
Query Neighborhood Hits	188	Target Neighborhood Hits	347	Shared Neighborhood Hits	41
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SAPS1_MOUSE
θ value	3.0926 (rank : 123)	NC score	0.021425 (rank : 202)
Query Neighborhood Hits	188	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SYN2_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.044354 (rank : 172)
Query Neighborhood Hits	188	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

ULK1_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.003559 (rank : 242)
Query Neighborhood Hits	188	Target Neighborhood Hits	1121	Shared Neighborhood Hits	32
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ACK1_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.005777 (rank : 237)
Query Neighborhood Hits	188	Target Neighborhood Hits	1140	Shared Neighborhood Hits	45
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.004654 (rank : 239)
Query Neighborhood Hits	188	Target Neighborhood Hits	1080	Shared Neighborhood Hits	41
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

HXA10_MOUSE
θ value	4.03905 (rank : 128)	NC score	0.009370 (rank : 227)
Query Neighborhood Hits	188	Target Neighborhood Hits	365	Shared Neighborhood Hits	6
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

K0082_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.032410 (rank : 186)
Query Neighborhood Hits	188	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBC3, Q3U3G5, Q3U7Y9, Q6A0D5, Q8C7V0	Gene names	Kiaa0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

MK07_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.003128 (rank : 244)
Query Neighborhood Hits	188	Target Neighborhood Hits	1054	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

NCOR2_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.027315 (rank : 193)
Query Neighborhood Hits	188	Target Neighborhood Hits	870	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PCLO_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.053339 (rank : 148)
Query Neighborhood Hits	188	Target Neighborhood Hits	2046	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RNF39_HUMAN
θ value	4.03905 (rank : 133)	NC score	0.019453 (rank : 207)
Query Neighborhood Hits	188	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

SMUF2_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.009155 (rank : 229)
Query Neighborhood Hits	188	Target Neighborhood Hits	142	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SP110_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.017177 (rank : 209)
Query Neighborhood Hits	188	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SPEG_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.006405 (rank : 235)
Query Neighborhood Hits	188	Target Neighborhood Hits	1762	Shared Neighborhood Hits	52
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ABLM2_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.003545 (rank : 243)
Query Neighborhood Hits	188	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BL65, Q6H8P8, Q80WK6, Q8BUT1, Q8BXI7	Gene names	Ablim2
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

APS_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.020514 (rank : 205)
Query Neighborhood Hits	188	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

MPDZ_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.010164 (rank : 226)
Query Neighborhood Hits	188	Target Neighborhood Hits	298	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

NCOA6_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.056782 (rank : 124)
Query Neighborhood Hits	188	Target Neighborhood Hits	1202	Shared Neighborhood Hits	78
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NOP14_MOUSE
θ value	5.27518 (rank : 141)	NC score	0.011280 (rank : 222)
Query Neighborhood Hits	188	Target Neighborhood Hits	324	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PRDM4_MOUSE
θ value	5.27518 (rank : 142)	NC score	-0.001609 (rank : 249)
Query Neighborhood Hits	188	Target Neighborhood Hits	744	Shared Neighborhood Hits	5
SwissProt Accessions	Q80V63	Gene names	Prdm4
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 4 (PR domain-containing protein 4).

PRG4_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.035520 (rank : 182)
Query Neighborhood Hits	188	Target Neighborhood Hits	764	Shared Neighborhood Hits	38
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP40_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.049067 (rank : 168)
Query Neighborhood Hits	188	Target Neighborhood Hits	442	Shared Neighborhood Hits	22
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	5.27518 (rank : 145)	NC score	0.056135 (rank : 127)
Query Neighborhood Hits	188	Target Neighborhood Hits	447	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

SOX30_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.012898 (rank : 220)
Query Neighborhood Hits	188	Target Neighborhood Hits	374	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

TMM24_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.021348 (rank : 203)
Query Neighborhood Hits	188	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

TMM24_MOUSE
θ value	5.27518 (rank : 148)	NC score	0.020303 (rank : 206)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

WASIP_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.081518 (rank : 89)
Query Neighborhood Hits	188	Target Neighborhood Hits	392	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ADDA_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.011021 (rank : 223)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	11
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

CEND1_MOUSE
θ value	6.88961 (rank : 151)	NC score	0.266322 (rank : 59)
Query Neighborhood Hits	188	Target Neighborhood Hits	260	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

P85A_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.214293 (rank : 62)
Query Neighborhood Hits	188	Target Neighborhood Hits	435	Shared Neighborhood Hits	61
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PININ_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.014248 (rank : 216)
Query Neighborhood Hits	188	Target Neighborhood Hits	777	Shared Neighborhood Hits	29
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PRDM4_HUMAN
θ value	6.88961 (rank : 154)	NC score	-0.001967 (rank : 250)
Query Neighborhood Hits	188	Target Neighborhood Hits	749	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKN5, Q9UFA6	Gene names	PRDM4, PFM1
Domain Architecture
Description	PR domain zinc finger protein 4 (PR domain-containing protein 4).

REXO1_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.024001 (rank : 197)
Query Neighborhood Hits	188	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RFX5_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.015250 (rank : 213)
Query Neighborhood Hits	188	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P48382	Gene names	RFX5
Domain Architecture
Description	DNA-binding protein RFX5 (Regulatory factor X subunit 5).

ROBO3_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.001439 (rank : 246)
Query Neighborhood Hits	188	Target Neighborhood Hits	570	Shared Neighborhood Hits	13
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

RP3A_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.009203 (rank : 228)
Query Neighborhood Hits	188	Target Neighborhood Hits	305	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPB1_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.023959 (rank : 199)
Query Neighborhood Hits	188	Target Neighborhood Hits	362	Shared Neighborhood Hits	26
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	6.88961 (rank : 160)	NC score	0.023997 (rank : 198)
Query Neighborhood Hits	188	Target Neighborhood Hits	363	Shared Neighborhood Hits	26
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SPTB2_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.009118 (rank : 230)
Query Neighborhood Hits	188	Target Neighborhood Hits	748	Shared Neighborhood Hits	19
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SYN3_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.038265 (rank : 178)
Query Neighborhood Hits	188	Target Neighborhood Hits	200	Shared Neighborhood Hits	21
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

WFS1_HUMAN
θ value	6.88961 (rank : 163)	NC score	0.013014 (rank : 219)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

ARHGA_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.038025 (rank : 180)
Query Neighborhood Hits	188	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ATRX_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.008973 (rank : 231)
Query Neighborhood Hits	188	Target Neighborhood Hits	682	Shared Neighborhood Hits	24
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BRWD1_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.005558 (rank : 238)
Query Neighborhood Hits	188	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CASL_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.035695 (rank : 181)
Query Neighborhood Hits	188	Target Neighborhood Hits	259	Shared Neighborhood Hits	19
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

ENAH_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.034124 (rank : 184)
Query Neighborhood Hits	188	Target Neighborhood Hits	919	Shared Neighborhood Hits	48
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FILA_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.014594 (rank : 215)
Query Neighborhood Hits	188	Target Neighborhood Hits	685	Shared Neighborhood Hits	22
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FOXJ2_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.004542 (rank : 240)
Query Neighborhood Hits	188	Target Neighborhood Hits	239	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GAK8_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.057571 (rank : 122)
Query Neighborhood Hits	188	Target Neighborhood Hits	145	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GP142_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.004206 (rank : 241)
Query Neighborhood Hits	188	Target Neighborhood Hits	319	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQN9	Gene names	Gpr142
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 142.

IRS2_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.017099 (rank : 210)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MDC1_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.049553 (rank : 167)
Query Neighborhood Hits	188	Target Neighborhood Hits	998	Shared Neighborhood Hits	60
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MOV10_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.006369 (rank : 236)
Query Neighborhood Hits	188	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

PAK4_MOUSE
θ value	8.99809 (rank : 176)	NC score	-0.001516 (rank : 248)
Query Neighborhood Hits	188	Target Neighborhood Hits	1098	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PCQAP_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.033658 (rank : 185)
Query Neighborhood Hits	188	Target Neighborhood Hits	506	Shared Neighborhood Hits	38
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PTN23_MOUSE
θ value	8.99809 (rank : 178)	NC score	0.024315 (rank : 196)
Query Neighborhood Hits	188	Target Neighborhood Hits	726	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTPR2_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.007042 (rank : 233)
Query Neighborhood Hits	188	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

RECQ5_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.013270 (rank : 218)
Query Neighborhood Hits	188	Target Neighborhood Hits	390	Shared Neighborhood Hits	32
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SHAN2_MOUSE
θ value	8.99809 (rank : 181)	NC score	0.022228 (rank : 201)
Query Neighborhood Hits	188	Target Neighborhood Hits	446	Shared Neighborhood Hits	27
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SMAP1_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.010939 (rank : 224)
Query Neighborhood Hits	188	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SREC2_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.007920 (rank : 232)
Query Neighborhood Hits	188	Target Neighborhood Hits	645	Shared Neighborhood Hits	18
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TARA_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.038681 (rank : 177)
Query Neighborhood Hits	188	Target Neighborhood Hits	1626	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TTDN1_MOUSE
θ value	8.99809 (rank : 185)	NC score	0.025102 (rank : 195)
Query Neighborhood Hits	188	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D011	Gene names	Ttdn1
Domain Architecture	No domain graphic available
Description	TTD non-photosensitive 1 protein homolog.

TXLNA_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.006898 (rank : 234)
Query Neighborhood Hits	188	Target Neighborhood Hits	982	Shared Neighborhood Hits	26
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

WASIP_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.070886 (rank : 104)
Query Neighborhood Hits	188	Target Neighborhood Hits	458	Shared Neighborhood Hits	43
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ZO1_MOUSE
θ value	8.99809 (rank : 188)	NC score	0.011422 (rank : 221)
Query Neighborhood Hits	188	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ALEX_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.050168 (rank : 165)
Query Neighborhood Hits	188	Target Neighborhood Hits	361	Shared Neighborhood Hits	41
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BNIP2_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.052231 (rank : 153)
Query Neighborhood Hits	188	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.052197 (rank : 155)
Query Neighborhood Hits	188	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

CEND1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.247033 (rank : 60)
Query Neighborhood Hits	188	Target Neighborhood Hits	284	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.330229 (rank : 54)
Query Neighborhood Hits	188	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CPSF6_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.056005 (rank : 128)
Query Neighborhood Hits	188	Target Neighborhood Hits	359	Shared Neighborhood Hits	31
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.055375 (rank : 133)
Query Neighborhood Hits	188	Target Neighborhood Hits	356	Shared Neighborhood Hits	32
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

FA13A_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.066334 (rank : 112)
Query Neighborhood Hits	188	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.066954 (rank : 111)
Query Neighborhood Hits	188	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.052198 (rank : 154)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.052050 (rank : 156)
Query Neighborhood Hits	188	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GAK10_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.061655 (rank : 119)
Query Neighborhood Hits	188	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK17_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.050271 (rank : 163)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

GAK18_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.055978 (rank : 130)
Query Neighborhood Hits	188	Target Neighborhood Hits	116	Shared Neighborhood Hits	20
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK7_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.055254 (rank : 135)
Query Neighborhood Hits	188	Target Neighborhood Hits	90	Shared Neighborhood Hits	23
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

GAK9_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.050198 (rank : 164)
Query Neighborhood Hits	188	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

K1683_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.056239 (rank : 126)
Query Neighborhood Hits	188	Target Neighborhood Hits	240	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MY18A_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.050045 (rank : 166)
Query Neighborhood Hits	188	Target Neighborhood Hits	1929	Shared Neighborhood Hits	49
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18B_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.054328 (rank : 145)
Query Neighborhood Hits	188	Target Neighborhood Hits	1299	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH10_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.054667 (rank : 141)
Query Neighborhood Hits	188	Target Neighborhood Hits	1620	Shared Neighborhood Hits	32
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.055078 (rank : 138)
Query Neighborhood Hits	188	Target Neighborhood Hits	1612	Shared Neighborhood Hits	33
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.054509 (rank : 143)
Query Neighborhood Hits	188	Target Neighborhood Hits	1806	Shared Neighborhood Hits	42
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.054557 (rank : 142)
Query Neighborhood Hits	188	Target Neighborhood Hits	1777	Shared Neighborhood Hits	39
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH13_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.050832 (rank : 161)
Query Neighborhood Hits	188	Target Neighborhood Hits	1504	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH14_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.055198 (rank : 136)
Query Neighborhood Hits	188	Target Neighborhood Hits	995	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.055135 (rank : 137)
Query Neighborhood Hits	188	Target Neighborhood Hits	1225	Shared Neighborhood Hits	24
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.053746 (rank : 147)
Query Neighborhood Hits	188	Target Neighborhood Hits	1478	Shared Neighborhood Hits	28
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.053901 (rank : 146)
Query Neighborhood Hits	188	Target Neighborhood Hits	1461	Shared Neighborhood Hits	35
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.052744 (rank : 151)
Query Neighborhood Hits	188	Target Neighborhood Hits	1491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH3_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.055999 (rank : 129)
Query Neighborhood Hits	188	Target Neighborhood Hits	1660	Shared Neighborhood Hits	37
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH4_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.055483 (rank : 132)
Query Neighborhood Hits	188	Target Neighborhood Hits	1377	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH4_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.053077 (rank : 150)
Query Neighborhood Hits	188	Target Neighborhood Hits	1476	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.052434 (rank : 152)
Query Neighborhood Hits	188	Target Neighborhood Hits	1426	Shared Neighborhood Hits	27
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.053130 (rank : 149)
Query Neighborhood Hits	188	Target Neighborhood Hits	1501	Shared Neighborhood Hits	27
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.051010 (rank : 159)
Query Neighborhood Hits	188	Target Neighborhood Hits	1559	Shared Neighborhood Hits	28
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH8_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.055316 (rank : 134)
Query Neighborhood Hits	188	Target Neighborhood Hits	1610	Shared Neighborhood Hits	40
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.054989 (rank : 140)
Query Neighborhood Hits	188	Target Neighborhood Hits	1600	Shared Neighborhood Hits	37
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH9_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.055051 (rank : 139)
Query Neighborhood Hits	188	Target Neighborhood Hits	1762	Shared Neighborhood Hits	42
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.056470 (rank : 125)
Query Neighborhood Hits	188	Target Neighborhood Hits	1829	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO1A_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.082070 (rank : 84)
Query Neighborhood Hits	188	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBC5, Q9UQD7	Gene names	MYO1A, MYHL
Domain Architecture
Description	Myosin Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC).

MYO1B_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.081790 (rank : 86)
Query Neighborhood Hits	188	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

MYO1B_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.081924 (rank : 85)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

MYO1C_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.081760 (rank : 87)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	O00159	Gene names	MYO1C
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMI-beta) (MMIb).

MYO1C_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.081718 (rank : 88)
Query Neighborhood Hits	188	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTI7, O08571, O08834, Q9QW54	Gene names	Myo1c
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMIb).

MYO1D_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.081209 (rank : 90)
Query Neighborhood Hits	188	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	O94832, Q8NHP9	Gene names	MYO1D, KIAA0727
Domain Architecture
Description	Myosin Id.

MYO1D_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.081128 (rank : 91)
Query Neighborhood Hits	188	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q5SYD0, Q5SSK7, Q8BWY5	Gene names	Myo1d
Domain Architecture	No domain graphic available
Description	Myosin Id.

MYO1E_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.088792 (rank : 78)
Query Neighborhood Hits	188	Target Neighborhood Hits	293	Shared Neighborhood Hits	30
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.091928 (rank : 76)
Query Neighborhood Hits	188	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.092007 (rank : 75)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	21
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO5A_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.068914 (rank : 108)
Query Neighborhood Hits	188	Target Neighborhood Hits	1092	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.069888 (rank : 105)
Query Neighborhood Hits	188	Target Neighborhood Hits	1117	Shared Neighborhood Hits	21
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5B_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.074291 (rank : 96)
Query Neighborhood Hits	188	Target Neighborhood Hits	911	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO5C_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.069726 (rank : 106)
Query Neighborhood Hits	188	Target Neighborhood Hits	1206	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYO6_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.077904 (rank : 94)
Query Neighborhood Hits	188	Target Neighborhood Hits	727	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO6_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.078914 (rank : 93)
Query Neighborhood Hits	188	Target Neighborhood Hits	586	Shared Neighborhood Hits	15
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

P85A_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.216979 (rank : 61)
Query Neighborhood Hits	188	Target Neighborhood Hits	479	Shared Neighborhood Hits	61
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PI5PA_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.050856 (rank : 160)
Query Neighborhood Hits	188	Target Neighborhood Hits	749	Shared Neighborhood Hits	52
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PI5PA_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.055935 (rank : 131)
Query Neighborhood Hits	188	Target Neighborhood Hits	331	Shared Neighborhood Hits	33
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRP1_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.067941 (rank : 110)
Query Neighborhood Hits	188	Target Neighborhood Hits	385	Shared Neighborhood Hits	42
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRR13_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.084444 (rank : 81)
Query Neighborhood Hits	188	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RGS3_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.051952 (rank : 157)
Query Neighborhood Hits	188	Target Neighborhood Hits	1621	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SYN1_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.050785 (rank : 162)
Query Neighborhood Hits	188	Target Neighborhood Hits	419	Shared Neighborhood Hits	42
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

WBP4_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.057153 (rank : 123)
Query Neighborhood Hits	188	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

Hits sorted by NC score

K1688_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	188	Target Neighborhood Hits	188	Shared Neighborhood Hits	188
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.963138 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	188	Target Neighborhood Hits	217	Shared Neighborhood Hits	115
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

RHG25_MOUSE
NC score	0.599324 (rank : 3)	θ value	8.10077e-17 (rank : 3)
Query Neighborhood Hits	188	Target Neighborhood Hits	492	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG18_MOUSE
NC score	0.593873 (rank : 4)	θ value	1.47974e-10 (rank : 6)
Query Neighborhood Hits	188	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG18_HUMAN
NC score	0.593796 (rank : 5)	θ value	1.133e-10 (rank : 5)
Query Neighborhood Hits	188	Target Neighborhood Hits	90	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

3BP1_MOUSE
NC score	0.593394 (rank : 6)	θ value	1.80886e-08 (rank : 16)
Query Neighborhood Hits	188	Target Neighborhood Hits	238	Shared Neighborhood Hits	77
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG08_MOUSE
NC score	0.590182 (rank : 7)	θ value	4.30538e-10 (rank : 7)
Query Neighborhood Hits	188	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG25_HUMAN
NC score	0.586865 (rank : 8)	θ value	3.07829e-16 (rank : 4)
Query Neighborhood Hits	188	Target Neighborhood Hits	550	Shared Neighborhood Hits	64
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG08_HUMAN
NC score	0.582431 (rank : 9)	θ value	3.64472e-09 (rank : 10)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG01_HUMAN
NC score	0.581897 (rank : 10)	θ value	3.08544e-08 (rank : 19)
Query Neighborhood Hits	188	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

3BP1_HUMAN
NC score	0.569561 (rank : 11)	θ value	4.0297e-08 (rank : 20)
Query Neighborhood Hits	188	Target Neighborhood Hits	376	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG06_MOUSE
NC score	0.556398 (rank : 12)	θ value	2.88788e-06 (rank : 35)
Query Neighborhood Hits	188	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RGAP1_MOUSE
NC score	0.555543 (rank : 13)	θ value	1.53129e-07 (rank : 25)
Query Neighborhood Hits	188	Target Neighborhood Hits	185	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG06_HUMAN
NC score	0.555386 (rank : 14)	θ value	8.40245e-06 (rank : 40)
Query Neighborhood Hits	188	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RGAP1_HUMAN
NC score	0.546844 (rank : 15)	θ value	3.77169e-06 (rank : 36)
Query Neighborhood Hits	188	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

TCGAP_MOUSE
NC score	0.543275 (rank : 16)	θ value	6.21693e-09 (rank : 12)
Query Neighborhood Hits	188	Target Neighborhood Hits	409	Shared Neighborhood Hits	77
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG12_MOUSE
NC score	0.538222 (rank : 17)	θ value	3.77169e-06 (rank : 38)
Query Neighborhood Hits	188	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
NC score	0.537178 (rank : 18)	θ value	3.77169e-06 (rank : 37)
Query Neighborhood Hits	188	Target Neighborhood Hits	190	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG09_HUMAN
NC score	0.536518 (rank : 19)	θ value	0.000461057 (rank : 51)
Query Neighborhood Hits	188	Target Neighborhood Hits	186	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

TAGAP_MOUSE
NC score	0.534459 (rank : 20)	θ value	1.29631e-06 (rank : 33)
Query Neighborhood Hits	188	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_HUMAN
NC score	0.532817 (rank : 21)	θ value	9.92553e-07 (rank : 32)
Query Neighborhood Hits	188	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

GMIP_HUMAN
NC score	0.529033 (rank : 22)	θ value	0.000158464 (rank : 47)
Query Neighborhood Hits	188	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
NC score	0.522201 (rank : 23)	θ value	0.000602161 (rank : 52)
Query Neighborhood Hits	188	Target Neighborhood Hits	202	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHIO_MOUSE
NC score	0.511850 (rank : 24)	θ value	4.92598e-06 (rank : 39)
Query Neighborhood Hits	188	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

SRGP2_HUMAN
NC score	0.511750 (rank : 25)	θ value	1.38499e-08 (rank : 15)
Query Neighborhood Hits	188	Target Neighborhood Hits	331	Shared Neighborhood Hits	68
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
NC score	0.507828 (rank : 26)	θ value	1.80886e-08 (rank : 18)
Query Neighborhood Hits	188	Target Neighborhood Hits	324	Shared Neighborhood Hits	66
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG04_HUMAN
NC score	0.507501 (rank : 27)	θ value	7.59969e-07 (rank : 30)
Query Neighborhood Hits	188	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RBP1_MOUSE
NC score	0.505666 (rank : 28)	θ value	1.53129e-07 (rank : 24)
Query Neighborhood Hits	188	Target Neighborhood Hits	493	Shared Neighborhood Hits	62
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

OPHN1_HUMAN
NC score	0.501570 (rank : 29)	θ value	1.09739e-05 (rank : 42)
Query Neighborhood Hits	188	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

TCGAP_HUMAN
NC score	0.497836 (rank : 30)	θ value	2.13673e-09 (rank : 9)
Query Neighborhood Hits	188	Target Neighborhood Hits	872	Shared Neighborhood Hits	103
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

OPHN1_MOUSE
NC score	0.497552 (rank : 31)	θ value	2.44474e-05 (rank : 45)
Query Neighborhood Hits	188	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

CHIN_MOUSE
NC score	0.496545 (rank : 32)	θ value	3.41135e-07 (rank : 27)
Query Neighborhood Hits	188	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

FNBP2_HUMAN
NC score	0.494910 (rank : 33)	θ value	3.41135e-07 (rank : 28)
Query Neighborhood Hits	188	Target Neighborhood Hits	432	Shared Neighborhood Hits	70
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

SRGP1_HUMAN
NC score	0.492864 (rank : 34)	θ value	7.59969e-07 (rank : 31)
Query Neighborhood Hits	188	Target Neighborhood Hits	390	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

GRLF1_HUMAN
NC score	0.492234 (rank : 35)	θ value	0.000158464 (rank : 48)
Query Neighborhood Hits	188	Target Neighborhood Hits	167	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

CHIN_HUMAN
NC score	0.490345 (rank : 36)	θ value	1.69304e-06 (rank : 34)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
NC score	0.488261 (rank : 37)	θ value	1.09739e-05 (rank : 41)
Query Neighborhood Hits	188	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

ABR_HUMAN
NC score	0.486501 (rank : 38)	θ value	1.43324e-05 (rank : 43)
Query Neighborhood Hits	188	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

CE005_HUMAN
NC score	0.486452 (rank : 39)	θ value	1.38499e-08 (rank : 14)
Query Neighborhood Hits	188	Target Neighborhood Hits	213	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RBP1_HUMAN
NC score	0.485800 (rank : 40)	θ value	7.59969e-07 (rank : 29)
Query Neighborhood Hits	188	Target Neighborhood Hits	521	Shared Neighborhood Hits	61
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

BCR_HUMAN
NC score	0.484493 (rank : 41)	θ value	2.61198e-07 (rank : 26)
Query Neighborhood Hits	188	Target Neighborhood Hits	204	Shared Neighborhood Hits	61
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CE005_MOUSE
NC score	0.479284 (rank : 42)	θ value	8.97725e-08 (rank : 21)
Query Neighborhood Hits	188	Target Neighborhood Hits	238	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG26_HUMAN
NC score	0.460360 (rank : 43)	θ value	0.00228821 (rank : 55)
Query Neighborhood Hits	188	Target Neighborhood Hits	281	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG05_MOUSE
NC score	0.458239 (rank : 44)	θ value	0.00665767 (rank : 57)
Query Neighborhood Hits	188	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG07_MOUSE
NC score	0.451762 (rank : 45)	θ value	0.00020696 (rank : 49)
Query Neighborhood Hits	188	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.444921 (rank : 46)	θ value	0.000602161 (rank : 53)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	59
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG05_HUMAN
NC score	0.431187 (rank : 47)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	188	Target Neighborhood Hits	158	Shared Neighborhood Hits	63
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

STA13_HUMAN
NC score	0.408370 (rank : 48)	θ value	0.00390308 (rank : 56)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STAR8_MOUSE
NC score	0.402713 (rank : 49)	θ value	0.0961366 (rank : 68)
Query Neighborhood Hits	188	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.397043 (rank : 50)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	188	Target Neighborhood Hits	216	Shared Neighborhood Hits	66
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
NC score	0.392066 (rank : 51)	θ value	0.0736092 (rank : 64)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

MYO9B_HUMAN
NC score	0.347594 (rank : 52)	θ value	4.76016e-09 (rank : 11)
Query Neighborhood Hits	188	Target Neighborhood Hits	641	Shared Neighborhood Hits	86
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
NC score	0.347421 (rank : 53)	θ value	1.80886e-08 (rank : 17)
Query Neighborhood Hits	188	Target Neighborhood Hits	311	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CEND2_HUMAN
NC score	0.330229 (rank : 54)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	188	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

I5P2_HUMAN
NC score	0.321949 (rank : 55)	θ value	1.43324e-05 (rank : 44)
Query Neighborhood Hits	188	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

CEND3_HUMAN
NC score	0.308949 (rank : 56)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	188	Target Neighborhood Hits	275	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
NC score	0.306359 (rank : 57)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	188	Target Neighborhood Hits	228	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

OCRL_HUMAN
NC score	0.304116 (rank : 58)	θ value	0.000121331 (rank : 46)
Query Neighborhood Hits	188	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

CEND1_MOUSE
NC score	0.266322 (rank : 59)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	188	Target Neighborhood Hits	260	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.247033 (rank : 60)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	188	Target Neighborhood Hits	284	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

P85A_HUMAN
NC score	0.216979 (rank : 61)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	188	Target Neighborhood Hits	479	Shared Neighborhood Hits	61
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.214293 (rank : 62)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	188	Target Neighborhood Hits	435	Shared Neighborhood Hits	61
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

MYO15_HUMAN
NC score	0.153897 (rank : 63)	θ value	1.63604e-09 (rank : 8)
Query Neighborhood Hits	188	Target Neighborhood Hits	671	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO15_MOUSE
NC score	0.151261 (rank : 64)	θ value	1.53129e-07 (rank : 23)
Query Neighborhood Hits	188	Target Neighborhood Hits	467	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO7A_MOUSE
NC score	0.142230 (rank : 65)	θ value	8.11959e-09 (rank : 13)
Query Neighborhood Hits	188	Target Neighborhood Hits	235	Shared Neighborhood Hits	10
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.138634 (rank : 66)	θ value	1.17247e-07 (rank : 22)
Query Neighborhood Hits	188	Target Neighborhood Hits	209	Shared Neighborhood Hits	10
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO10_HUMAN
NC score	0.115817 (rank : 67)	θ value	0.00134147 (rank : 54)
Query Neighborhood Hits	188	Target Neighborhood Hits	920	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PRP2_MOUSE
NC score	0.111958 (rank : 68)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	188	Target Neighborhood Hits	347	Shared Neighborhood Hits	41
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SRRM1_MOUSE
NC score	0.109674 (rank : 69)	θ value	0.47712 (rank : 87)
Query Neighborhood Hits	188	Target Neighborhood Hits	966	Shared Neighborhood Hits	70
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ATX7_HUMAN
NC score	0.105058 (rank : 70)	θ value	0.0113563 (rank : 59)
Query Neighborhood Hits	188	Target Neighborhood Hits	351	Shared Neighborhood Hits	32
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

SRRM1_HUMAN
NC score	0.103907 (rank : 71)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	188	Target Neighborhood Hits	690	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ATX7_MOUSE
NC score	0.101248 (rank : 72)	θ value	0.0193708 (rank : 61)
Query Neighborhood Hits	188	Target Neighborhood Hits	328	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

SRRM2_HUMAN
NC score	0.099510 (rank : 73)	θ value	0.00020696 (rank : 50)
Query Neighborhood Hits	188	Target Neighborhood Hits	1296	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.097011 (rank : 74)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	188	Target Neighborhood Hits	1470	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MYO1F_MOUSE
NC score	0.092007 (rank : 75)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	21
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO1F_HUMAN
NC score	0.091928 (rank : 76)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	188	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

WBP4_MOUSE
NC score	0.089112 (rank : 77)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

MYO1E_HUMAN
NC score	0.088792 (rank : 78)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	188	Target Neighborhood Hits	293	Shared Neighborhood Hits	30
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

ARI1B_HUMAN
NC score	0.086989 (rank : 79)	θ value	0.00869519 (rank : 58)
Query Neighborhood Hits	188	Target Neighborhood Hits	567	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARI1A_HUMAN
NC score	0.086877 (rank : 80)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	188	Target Neighborhood Hits	787	Shared Neighborhood Hits	62
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

PRR13_MOUSE
NC score	0.084444 (rank : 81)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	188	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RERE_HUMAN
NC score	0.082494 (rank : 82)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	188	Target Neighborhood Hits	779	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
NC score	0.082272 (rank : 83)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	188	Target Neighborhood Hits	785	Shared Neighborhood Hits	49
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MYO1A_HUMAN
NC score	0.082070 (rank : 84)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	188	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBC5, Q9UQD7	Gene names	MYO1A, MYHL
Domain Architecture
Description	Myosin Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC).

MYO1B_MOUSE
NC score	0.081924 (rank : 85)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	P46735, P70244	Gene names	Myo1b
Domain Architecture
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L).

MYO1B_HUMAN
NC score	0.081790 (rank : 86)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	188	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	O43795, O43794, Q7Z6L5	Gene names	MYO1B
Domain Architecture	No domain graphic available
Description	Myosin Ib (Myosin I alpha) (MMI-alpha) (MMIa) (MYH-1c).

MYO1C_HUMAN
NC score	0.081760 (rank : 87)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	O00159	Gene names	MYO1C
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMI-beta) (MMIb).

MYO1C_MOUSE
NC score	0.081718 (rank : 88)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	188	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTI7, O08571, O08834, Q9QW54	Gene names	Myo1c
Domain Architecture
Description	Myosin Ic (Myosin I beta) (MMIb).

WASIP_MOUSE
NC score	0.081518 (rank : 89)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	188	Target Neighborhood Hits	392	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

MYO1D_HUMAN
NC score	0.081209 (rank : 90)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	188	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	O94832, Q8NHP9	Gene names	MYO1D, KIAA0727
Domain Architecture
Description	Myosin Id.

MYO1D_MOUSE
NC score	0.081128 (rank : 91)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	188	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q5SYD0, Q5SSK7, Q8BWY5	Gene names	Myo1d
Domain Architecture	No domain graphic available
Description	Myosin Id.

UBN1_HUMAN
NC score	0.080920 (rank : 92)	θ value	0.0113563 (rank : 60)
Query Neighborhood Hits	188	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

MYO6_MOUSE
NC score	0.078914 (rank : 93)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	188	Target Neighborhood Hits	586	Shared Neighborhood Hits	15
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO6_HUMAN
NC score	0.077904 (rank : 94)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	188	Target Neighborhood Hits	727	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

BCAR1_MOUSE
NC score	0.075684 (rank : 95)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	188	Target Neighborhood Hits	438	Shared Neighborhood Hits	51
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MYO5B_HUMAN
NC score	0.074291 (rank : 96)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	188	Target Neighborhood Hits	911	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

PRB4S_HUMAN
NC score	0.073123 (rank : 97)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	188	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

BCAR1_HUMAN
NC score	0.072710 (rank : 98)	θ value	0.0961366 (rank : 65)
Query Neighborhood Hits	188	Target Neighborhood Hits	554	Shared Neighborhood Hits	56
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

GAK6_HUMAN
NC score	0.072056 (rank : 99)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	188	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
NC score	0.071979 (rank : 100)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	188	Target Neighborhood Hits	429	Shared Neighborhood Hits	44
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.071353 (rank : 101)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	188	Target Neighborhood Hits	415	Shared Neighborhood Hits	44
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.071284 (rank : 102)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	188	Target Neighborhood Hits	409	Shared Neighborhood Hits	44
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.071041 (rank : 103)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	188	Target Neighborhood Hits	406	Shared Neighborhood Hits	43
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

WASIP_HUMAN
NC score	0.070886 (rank : 104)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	188	Target Neighborhood Hits	458	Shared Neighborhood Hits	43
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MYO5A_MOUSE
NC score	0.069888 (rank : 105)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	188	Target Neighborhood Hits	1117	Shared Neighborhood Hits	21
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5C_HUMAN
NC score	0.069726 (rank : 106)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	188	Target Neighborhood Hits	1206	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

CIP4_HUMAN
NC score	0.069188 (rank : 107)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	188	Target Neighborhood Hits	374	Shared Neighborhood Hits	12
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

MYO5A_HUMAN
NC score	0.068914 (rank : 108)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	188	Target Neighborhood Hits	1092	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

GAK12_HUMAN
NC score	0.068401 (rank : 109)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	188	Target Neighborhood Hits	374	Shared Neighborhood Hits	38
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PRP1_HUMAN
NC score	0.067941 (rank : 110)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	188	Target Neighborhood Hits	385	Shared Neighborhood Hits	42
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

FA13A_MOUSE
NC score	0.066954 (rank : 111)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	188	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13A_HUMAN
NC score	0.066334 (rank : 112)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	188	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

PQBP1_MOUSE
NC score	0.065940 (rank : 113)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	188	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

GAK1_HUMAN
NC score	0.064685 (rank : 114)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	188	Target Neighborhood Hits	268	Shared Neighborhood Hits	30
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PQBP1_HUMAN
NC score	0.064420 (rank : 115)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

IASPP_MOUSE
NC score	0.064255 (rank : 116)	θ value	0.0330416 (rank : 62)
Query Neighborhood Hits	188	Target Neighborhood Hits	1024	Shared Neighborhood Hits	62
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MDC1_HUMAN
NC score	0.063972 (rank : 117)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	188	Target Neighborhood Hits	1446	Shared Neighborhood Hits	72
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

GAK3_HUMAN
NC score	0.062970 (rank : 118)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	188	Target Neighborhood Hits	182	Shared Neighborhood Hits	23
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK10_HUMAN
NC score	0.061655 (rank : 119)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	188	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RGS3_HUMAN
NC score	0.059133 (rank : 120)	θ value	0.0330416 (rank : 63)
Query Neighborhood Hits	188	Target Neighborhood Hits	1375	Shared Neighborhood Hits	70
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PKHA1_HUMAN
NC score	0.058626 (rank : 121)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	188	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

GAK8_HUMAN
NC score	0.057571 (rank : 122)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	188	Target Neighborhood Hits	145	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

WBP4_HUMAN
NC score	0.057153 (rank : 123)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	188	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	O75554	Gene names	WBP4, FBP21, FNBP21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

NCOA6_HUMAN
NC score	0.056782 (rank : 124)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	188	Target Neighborhood Hits	1202	Shared Neighborhood Hits	78
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MYH9_MOUSE
NC score	0.056470 (rank : 125)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	188	Target Neighborhood Hits	1829	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

K1683_HUMAN
NC score	0.056239 (rank : 126)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	188	Target Neighborhood Hits	240	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

PRP40_MOUSE
NC score	0.056135 (rank : 127)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	188	Target Neighborhood Hits	447	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

CPSF6_HUMAN
NC score	0.056005 (rank : 128)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	188	Target Neighborhood Hits	359	Shared Neighborhood Hits	31
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

MYH3_HUMAN
NC score	0.055999 (rank : 129)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	188	Target Neighborhood Hits	1660	Shared Neighborhood Hits	37
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

GAK18_HUMAN
NC score	0.055978 (rank : 130)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	188	Target Neighborhood Hits	116	Shared Neighborhood Hits	20
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PI5PA_MOUSE
NC score	0.055935 (rank : 131)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	188	Target Neighborhood Hits	331	Shared Neighborhood Hits	33
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MYH4_HUMAN
NC score	0.055483 (rank : 132)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	188	Target Neighborhood Hits	1377	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

CPSF6_MOUSE
NC score	0.055375 (rank : 133)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	188	Target Neighborhood Hits	356	Shared Neighborhood Hits	32
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

MYH8_HUMAN
NC score	0.055316 (rank : 134)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	188	Target Neighborhood Hits	1610	Shared Neighborhood Hits	40
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

GAK7_HUMAN
NC score	0.055254 (rank : 135)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	188	Target Neighborhood Hits	90	Shared Neighborhood Hits	23
SwissProt Accessions	Q96PI4, Q9QC08	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K18 Gag protein) (HERV-K110 Gag protein) (HERV-K(C1a) Gag protein) [Contains: Matrix protein].

MYH14_HUMAN
NC score	0.055198 (rank : 136)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	188	Target Neighborhood Hits	995	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
NC score	0.055135 (rank : 137)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	188	Target Neighborhood Hits	1225	Shared Neighborhood Hits	24
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH10_MOUSE
NC score	0.055078 (rank : 138)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	188	Target Neighborhood Hits	1612	Shared Neighborhood Hits	33
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_HUMAN
NC score	0.055051 (rank : 139)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	188	Target Neighborhood Hits	1762	Shared Neighborhood Hits	42
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH8_MOUSE
NC score	0.054989 (rank : 140)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	188	Target Neighborhood Hits	1600	Shared Neighborhood Hits	37
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH10_HUMAN
NC score	0.054667 (rank : 141)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	188	Target Neighborhood Hits	1620	Shared Neighborhood Hits	32
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_MOUSE
NC score	0.054557 (rank : 142)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	188	Target Neighborhood Hits	1777	Shared Neighborhood Hits	39
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_HUMAN
NC score	0.054509 (rank : 143)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	188	Target Neighborhood Hits	1806	Shared Neighborhood Hits	42
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PKHA1_MOUSE
NC score	0.054349 (rank : 144)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	188	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

MY18B_HUMAN
NC score	0.054328 (rank : 145)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	188	Target Neighborhood Hits	1299	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH1_MOUSE
NC score	0.053901 (rank : 146)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	188	Target Neighborhood Hits	1461	Shared Neighborhood Hits	35
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH1_HUMAN
NC score	0.053746 (rank : 147)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	188	Target Neighborhood Hits	1478	Shared Neighborhood Hits	28
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

PCLO_HUMAN
NC score	0.053339 (rank : 148)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	188	Target Neighborhood Hits	2046	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MYH6_MOUSE
NC score	0.053130 (rank : 149)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	188	Target Neighborhood Hits	1501	Shared Neighborhood Hits	27
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH4_MOUSE
NC score	0.053077 (rank : 150)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	188	Target Neighborhood Hits	1476	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH2_HUMAN
NC score	0.052744 (rank : 151)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	188	Target Neighborhood Hits	1491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH6_HUMAN
NC score	0.052434 (rank : 152)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	188	Target Neighborhood Hits	1426	Shared Neighborhood Hits	27
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

BNIP2_HUMAN
NC score	0.052231 (rank : 153)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	188	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

FA13C_HUMAN
NC score	0.052198 (rank : 154)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

BNIP2_MOUSE
NC score	0.052197 (rank : 155)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	188	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

FA13C_MOUSE
NC score	0.052050 (rank : 156)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	188	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

RGS3_MOUSE
NC score	0.051952 (rank : 157)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	188	Target Neighborhood Hits	1621	Shared Neighborhood Hits	92
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

VINEX_MOUSE
NC score	0.051416 (rank : 158)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	188	Target Neighborhood Hits	286	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

MYH7_HUMAN
NC score	0.051010 (rank : 159)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	188	Target Neighborhood Hits	1559	Shared Neighborhood Hits	28
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PI5PA_HUMAN
NC score	0.050856 (rank : 160)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	188	Target Neighborhood Hits	749	Shared Neighborhood Hits	52
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MYH13_HUMAN
NC score	0.050832 (rank : 161)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	188	Target Neighborhood Hits	1504	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

SYN1_HUMAN
NC score	0.050785 (rank : 162)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	188	Target Neighborhood Hits	419	Shared Neighborhood Hits	42
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

GAK17_HUMAN
NC score	0.050271 (rank : 163)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P62689	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein].

GAK9_HUMAN
NC score	0.050198 (rank : 164)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	188	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKH8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K104 Gag protein) [Contains: Matrix protein].

ALEX_HUMAN
NC score	0.050168 (rank : 165)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	188	Target Neighborhood Hits	361	Shared Neighborhood Hits	41
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

MY18A_HUMAN
NC score	0.050045 (rank : 166)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	188	Target Neighborhood Hits	1929	Shared Neighborhood Hits	49
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MDC1_MOUSE
NC score	0.049553 (rank : 167)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	188	Target Neighborhood Hits	998	Shared Neighborhood Hits	60
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PRP40_HUMAN
NC score	0.049067 (rank : 168)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	188	Target Neighborhood Hits	442	Shared Neighborhood Hits	22
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

R51A1_MOUSE
NC score	0.047918 (rank : 169)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	188	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

MINT_MOUSE
NC score	0.046893 (rank : 170)	θ value	0.0961366 (rank : 67)
Query Neighborhood Hits	188	Target Neighborhood Hits	1514	Shared Neighborhood Hits	58
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SMYD4_HUMAN
NC score	0.044856 (rank : 171)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SYN2_MOUSE
NC score	0.044354 (rank : 172)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	188	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

SAPS1_HUMAN
NC score	0.042558 (rank : 173)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	188	Target Neighborhood Hits	704	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ECM1_HUMAN
NC score	0.041517 (rank : 174)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	188	Target Neighborhood Hits	182	Shared Neighborhood Hits	24
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

CK024_HUMAN
NC score	0.039783 (rank : 175)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	188	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

PPRB_MOUSE
NC score	0.038904 (rank : 176)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	188	Target Neighborhood Hits	354	Shared Neighborhood Hits	25
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

TARA_HUMAN
NC score	0.038681 (rank : 177)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	188	Target Neighborhood Hits	1626	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SYN3_MOUSE
NC score	0.038265 (rank : 178)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	188	Target Neighborhood Hits	200	Shared Neighborhood Hits	21
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

MILK2_HUMAN
NC score	0.038077 (rank : 179)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	188	Target Neighborhood Hits	457	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

ARHGA_HUMAN
NC score	0.038025 (rank : 180)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	188	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

CASL_HUMAN
NC score	0.035695 (rank : 181)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	188	Target Neighborhood Hits	259	Shared Neighborhood Hits	19
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

PRG4_HUMAN
NC score	0.035520 (rank : 182)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	188	Target Neighborhood Hits	764	Shared Neighborhood Hits	38
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SPN90_MOUSE
NC score	0.034404 (rank : 183)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	188	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

ENAH_MOUSE
NC score	0.034124 (rank : 184)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	188	Target Neighborhood Hits	919	Shared Neighborhood Hits	48
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PCQAP_MOUSE
NC score	0.033658 (rank : 185)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	188	Target Neighborhood Hits	506	Shared Neighborhood Hits	38
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

K0082_MOUSE
NC score	0.032410 (rank : 186)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	188	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBC3, Q3U3G5, Q3U7Y9, Q6A0D5, Q8C7V0	Gene names	Kiaa0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

CABYR_HUMAN
NC score	0.031603 (rank : 187)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

ATX2_MOUSE
NC score	0.031112 (rank : 188)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	35
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

HGS_MOUSE
NC score	0.030974 (rank : 189)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	188	Target Neighborhood Hits	589	Shared Neighborhood Hits	33
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

EP400_MOUSE
NC score	0.030174 (rank : 190)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	188	Target Neighborhood Hits	592	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ZCPW1_HUMAN
NC score	0.029390 (rank : 191)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	188	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

UBP2L_HUMAN
NC score	0.027818 (rank : 192)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	188	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

NCOR2_HUMAN
NC score	0.027315 (rank : 193)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	188	Target Neighborhood Hits	870	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TOB1_MOUSE
NC score	0.027296 (rank : 194)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	188	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q61471	Gene names	Tob1, Tob, Trob
Domain Architecture
Description	Tob1 protein (Transducer of erbB-2 1).

TTDN1_MOUSE
NC score	0.025102 (rank : 195)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	188	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D011	Gene names	Ttdn1
Domain Architecture	No domain graphic available
Description	TTD non-photosensitive 1 protein homolog.

PTN23_MOUSE
NC score	0.024315 (rank : 196)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	188	Target Neighborhood Hits	726	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

REXO1_HUMAN
NC score	0.024001 (rank : 197)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	188	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RPB1_MOUSE
NC score	0.023997 (rank : 198)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	188	Target Neighborhood Hits	363	Shared Neighborhood Hits	26
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.023959 (rank : 199)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	188	Target Neighborhood Hits	362	Shared Neighborhood Hits	26
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SYGP1_HUMAN
NC score	0.022811 (rank : 200)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	188	Target Neighborhood Hits	589	Shared Neighborhood Hits	14
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

SHAN2_MOUSE
NC score	0.022228 (rank : 201)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	188	Target Neighborhood Hits	446	Shared Neighborhood Hits	27
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SAPS1_MOUSE
NC score	0.021425 (rank : 202)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	188	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

TMM24_HUMAN
NC score	0.021348 (rank : 203)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	188	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O14523, Q86UT7, Q8N522, Q8TBN4, Q96G10	Gene names	TMEM24, KIAA0285
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24 (Protein DLNB23).

NOS2A_HUMAN
NC score	0.020633 (rank : 204)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

APS_HUMAN
NC score	0.020514 (rank : 205)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	188	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	O14492	Gene names	APS
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

TMM24_MOUSE
NC score	0.020303 (rank : 206)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X80	Gene names	Tmem24
Domain Architecture	No domain graphic available
Description	Transmembrane protein 24.

RNF39_HUMAN
NC score	0.019453 (rank : 207)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	188	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

LAP4_HUMAN
NC score	0.017316 (rank : 208)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	188	Target Neighborhood Hits	608	Shared Neighborhood Hits	16
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

SP110_HUMAN
NC score	0.017177 (rank : 209)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	188	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

IRS2_HUMAN
NC score	0.017099 (rank : 210)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	188	Target Neighborhood Hits	262	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

SOAT2_HUMAN
NC score	0.016951 (rank : 211)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	188	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O75908, Q96TD4, Q9UNR2	Gene names	SOAT2, ACACT2, ACAT2
Domain Architecture
Description	Sterol O-acyltransferase 2 (EC 2.3.1.26) (Cholesterol acyltransferase 2) (Acyl coenzyme A:cholesterol acyltransferase 2) (ACAT-2).

GMCL1_MOUSE
NC score	0.015604 (rank : 212)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q920G9, Q9DBW5, Q9QUP6	Gene names	Gmcl1, Gcl, Gcl1
Domain Architecture
Description	Germ cell-less protein-like 1 (mGcl-1) (DP-interacting protein) (DIP).

RFX5_HUMAN
NC score	0.015250 (rank : 213)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	188	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P48382	Gene names	RFX5
Domain Architecture
Description	DNA-binding protein RFX5 (Regulatory factor X subunit 5).

LAP4_MOUSE
NC score	0.014753 (rank : 214)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	188	Target Neighborhood Hits	590	Shared Neighborhood Hits	16
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

FILA_HUMAN
NC score	0.014594 (rank : 215)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	188	Target Neighborhood Hits	685	Shared Neighborhood Hits	22
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

PININ_MOUSE
NC score	0.014248 (rank : 216)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	188	Target Neighborhood Hits	777	Shared Neighborhood Hits	29
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

CUTL2_HUMAN
NC score	0.013858 (rank : 217)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	188	Target Neighborhood Hits	906	Shared Neighborhood Hits	23
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

RECQ5_HUMAN
NC score	0.013270 (rank : 218)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	188	Target Neighborhood Hits	390	Shared Neighborhood Hits	32
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WFS1_HUMAN
NC score	0.013014 (rank : 219)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

SOX30_MOUSE
NC score	0.012898 (rank : 220)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	188	Target Neighborhood Hits	374	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ZO1_MOUSE
NC score	0.011422 (rank : 221)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	188	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

NOP14_MOUSE
NC score	0.011280 (rank : 222)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	188	Target Neighborhood Hits	324	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

ADDA_HUMAN
NC score	0.011021 (rank : 223)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	11
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

SMAP1_HUMAN
NC score	0.010939 (rank : 224)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	188	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SREC2_MOUSE
NC score	0.010775 (rank : 225)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	188	Target Neighborhood Hits	605	Shared Neighborhood Hits	20
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

MPDZ_MOUSE
NC score	0.010164 (rank : 226)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	188	Target Neighborhood Hits	298	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

HXA10_MOUSE
NC score	0.009370 (rank : 227)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	188	Target Neighborhood Hits	365	Shared Neighborhood Hits	6
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

RP3A_HUMAN
NC score	0.009203 (rank : 228)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	188	Target Neighborhood Hits	305	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SMUF2_HUMAN
NC score	0.009155 (rank : 229)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	188	Target Neighborhood Hits	142	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SPTB2_HUMAN
NC score	0.009118 (rank : 230)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	188	Target Neighborhood Hits	748	Shared Neighborhood Hits	19
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

ATRX_MOUSE
NC score	0.008973 (rank : 231)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	188	Target Neighborhood Hits	682	Shared Neighborhood Hits	24
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SREC2_HUMAN
NC score	0.007920 (rank : 232)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	188	Target Neighborhood Hits	645	Shared Neighborhood Hits	18
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

PTPR2_MOUSE
NC score	0.007042 (rank : 233)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	188	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

TXLNA_HUMAN
NC score	0.006898 (rank : 234)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	188	Target Neighborhood Hits	982	Shared Neighborhood Hits	26
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

SPEG_HUMAN
NC score	0.006405 (rank : 235)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	188	Target Neighborhood Hits	1762	Shared Neighborhood Hits	52
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MOV10_MOUSE
NC score	0.006369 (rank : 236)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	188	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

ACK1_HUMAN
NC score	0.005777 (rank : 237)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	188	Target Neighborhood Hits	1140	Shared Neighborhood Hits	45
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

BRWD1_MOUSE
NC score	0.005558 (rank : 238)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	188	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

ACK1_MOUSE
NC score	0.004654 (rank : 239)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	188	Target Neighborhood Hits	1080	Shared Neighborhood Hits	41
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

FOXJ2_HUMAN
NC score	0.004542 (rank : 240)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	188	Target Neighborhood Hits	239	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GP142_MOUSE
NC score	0.004206 (rank : 241)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	188	Target Neighborhood Hits	319	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQN9	Gene names	Gpr142
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 142.

ULK1_HUMAN
NC score	0.003559 (rank : 242)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	188	Target Neighborhood Hits	1121	Shared Neighborhood Hits	32
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ABLM2_MOUSE
NC score	0.003545 (rank : 243)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	188	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BL65, Q6H8P8, Q80WK6, Q8BUT1, Q8BXI7	Gene names	Ablim2
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

MK07_MOUSE
NC score	0.003128 (rank : 244)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	188	Target Neighborhood Hits	1054	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MK07_HUMAN
NC score	0.002156 (rank : 245)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	188	Target Neighborhood Hits	1087	Shared Neighborhood Hits	25
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

ROBO3_HUMAN
NC score	0.001439 (rank : 246)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	188	Target Neighborhood Hits	570	Shared Neighborhood Hits	13
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

KKCC2_HUMAN
NC score	0.000918 (rank : 247)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	188	Target Neighborhood Hits	852	Shared Neighborhood Hits	10
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

PAK4_MOUSE
NC score	-0.001516 (rank : 248)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	188	Target Neighborhood Hits	1098	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PRDM4_MOUSE
NC score	-0.001609 (rank : 249)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	188	Target Neighborhood Hits	744	Shared Neighborhood Hits	5
SwissProt Accessions	Q80V63	Gene names	Prdm4
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 4 (PR domain-containing protein 4).

PRDM4_HUMAN
NC score	-0.001967 (rank : 250)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	188	Target Neighborhood Hits	749	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKN5, Q9UFA6	Gene names	PRDM4, PFM1
Domain Architecture
Description	PR domain zinc finger protein 4 (PR domain-containing protein 4).

ZN509_HUMAN
NC score	-0.003512 (rank : 251)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	188	Target Neighborhood Hits	846	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZSB9, Q59FJ4, Q5EBN0, Q8TB80	Gene names	ZNF509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.