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Network neighborhood for query Sequence : LAP4_HUMAN

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LAP4_HUMAN
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LAP4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	608	Target Neighborhood Hits	608	Shared Neighborhood Hits	608
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
θ value	0 (rank : 2)	NC score	0.991487 (rank : 2)
Query Neighborhood Hits	608	Target Neighborhood Hits	590	Shared Neighborhood Hits	490
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LRRC1_MOUSE
θ value	2.658e-177 (rank : 3)	NC score	0.820242 (rank : 8)
Query Neighborhood Hits	608	Target Neighborhood Hits	281	Shared Neighborhood Hits	238
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

LRRC1_HUMAN
θ value	7.7336e-177 (rank : 4)	NC score	0.820636 (rank : 7)
Query Neighborhood Hits	608	Target Neighborhood Hits	282	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LAP2_MOUSE
θ value	3.54468e-105 (rank : 5)	NC score	0.885210 (rank : 6)
Query Neighborhood Hits	608	Target Neighborhood Hits	482	Shared Neighborhood Hits	336
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_HUMAN
θ value	2.01279e-100 (rank : 6)	NC score	0.887087 (rank : 5)
Query Neighborhood Hits	608	Target Neighborhood Hits	499	Shared Neighborhood Hits	343
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LRRC7_HUMAN
θ value	8.4565e-99 (rank : 7)	NC score	0.890320 (rank : 4)
Query Neighborhood Hits	608	Target Neighborhood Hits	423	Shared Neighborhood Hits	348
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	8.4565e-99 (rank : 8)	NC score	0.891728 (rank : 3)
Query Neighborhood Hits	608	Target Neighborhood Hits	416	Shared Neighborhood Hits	350
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

SHOC2_MOUSE
θ value	2.76489e-41 (rank : 9)	NC score	0.780504 (rank : 9)
Query Neighborhood Hits	608	Target Neighborhood Hits	308	Shared Neighborhood Hits	241
SwissProt Accessions	O88520, Q3UJH6, Q8BVL0	Gene names	Shoc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

SHOC2_HUMAN
θ value	6.15952e-41 (rank : 10)	NC score	0.780054 (rank : 10)
Query Neighborhood Hits	608	Target Neighborhood Hits	330	Shared Neighborhood Hits	239
SwissProt Accessions	Q9UQ13, O76063	Gene names	SHOC2, KIAA0862
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

DLG4_HUMAN
θ value	1.98146e-39 (rank : 11)	NC score	0.519368 (rank : 170)
Query Neighborhood Hits	608	Target Neighborhood Hits	286	Shared Neighborhood Hits	185
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	1.98146e-39 (rank : 12)	NC score	0.520287 (rank : 169)
Query Neighborhood Hits	608	Target Neighborhood Hits	282	Shared Neighborhood Hits	187
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG1_HUMAN
θ value	1.28434e-38 (rank : 13)	NC score	0.510548 (rank : 183)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	176
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

MPDZ_MOUSE
θ value	6.37413e-38 (rank : 14)	NC score	0.551118 (rank : 127)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	208
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

DLG1_MOUSE
θ value	4.568e-36 (rank : 15)	NC score	0.508865 (rank : 188)
Query Neighborhood Hits	608	Target Neighborhood Hits	285	Shared Neighborhood Hits	176
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

MPDZ_HUMAN
θ value	1.6247e-33 (rank : 16)	NC score	0.549745 (rank : 128)
Query Neighborhood Hits	608	Target Neighborhood Hits	261	Shared Neighborhood Hits	206
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

DLG2_HUMAN
θ value	1.37539e-32 (rank : 17)	NC score	0.508733 (rank : 189)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	183
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

INADL_HUMAN
θ value	1.16434e-31 (rank : 18)	NC score	0.548483 (rank : 132)
Query Neighborhood Hits	608	Target Neighborhood Hits	260	Shared Neighborhood Hits	195
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

DLG3_MOUSE
θ value	1.98606e-31 (rank : 19)	NC score	0.507449 (rank : 190)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	184
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

LRC40_MOUSE
θ value	2.86786e-30 (rank : 20)	NC score	0.759275 (rank : 11)
Query Neighborhood Hits	608	Target Neighborhood Hits	311	Shared Neighborhood Hits	241
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

INADL_MOUSE
θ value	2.42779e-29 (rank : 21)	NC score	0.548765 (rank : 130)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	201
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LRC40_HUMAN
θ value	1.02001e-27 (rank : 22)	NC score	0.759238 (rank : 12)
Query Neighborhood Hits	608	Target Neighborhood Hits	313	Shared Neighborhood Hits	243
SwissProt Accessions	Q9H9A6, Q9BTR7, Q9NSK1, Q9NXC1	Gene names	LRRC40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

GPV_MOUSE
θ value	1.92365e-26 (rank : 23)	NC score	0.675778 (rank : 43)
Query Neighborhood Hits	608	Target Neighborhood Hits	293	Shared Neighborhood Hits	243
SwissProt Accessions	O08742	Gene names	Gp5
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

FLII_HUMAN
θ value	2.51237e-26 (rank : 24)	NC score	0.654765 (rank : 59)
Query Neighborhood Hits	608	Target Neighborhood Hits	318	Shared Neighborhood Hits	238
SwissProt Accessions	Q13045	Gene names	FLII, FLIL
Domain Architecture
Description	Protein flightless-1 homolog.

LRC8A_MOUSE
θ value	7.30988e-26 (rank : 25)	NC score	0.691106 (rank : 34)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	232
SwissProt Accessions	Q80WG5	Gene names	Lrrc8a, Lrrc8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

FLII_MOUSE
θ value	1.24688e-25 (rank : 26)	NC score	0.653387 (rank : 60)
Query Neighborhood Hits	608	Target Neighborhood Hits	304	Shared Neighborhood Hits	232
SwissProt Accessions	Q9JJ28, Q8K095, Q8VI44	Gene names	Flii, Fli1, Fliih
Domain Architecture	No domain graphic available
Description	Protein flightless-1 homolog.

LRC8A_HUMAN
θ value	1.24688e-25 (rank : 27)	NC score	0.692011 (rank : 32)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	232
SwissProt Accessions	Q8IWT6, Q6UXM2, Q8NCI0, Q9P2B1	Gene names	LRRC8A, KIAA1437, LRRC8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

DLG2_MOUSE
θ value	2.12685e-25 (rank : 28)	NC score	0.503902 (rank : 197)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	182
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LRC8B_HUMAN
θ value	4.73814e-25 (rank : 29)	NC score	0.687640 (rank : 36)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	232
SwissProt Accessions	Q6P9F7, Q6UY21, Q8N106, Q92627	Gene names	LRRC8B, KIAA0231
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8B (T-cell activation leucine repeat-rich protein).

DLG3_HUMAN
θ value	1.80048e-24 (rank : 30)	NC score	0.503880 (rank : 198)
Query Neighborhood Hits	608	Target Neighborhood Hits	269	Shared Neighborhood Hits	184
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

LRC39_HUMAN
θ value	1.80048e-24 (rank : 31)	NC score	0.749124 (rank : 14)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	220
SwissProt Accessions	Q96DD0, Q5VVK7	Gene names	LRRC39
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 39 (Densin hlg).

LRC8D_MOUSE
θ value	4.01107e-24 (rank : 32)	NC score	0.696491 (rank : 29)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	238
SwissProt Accessions	Q8BGR2, Q3UVA9, Q8CI13	Gene names	Lrrc8d, Lrrc5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

LRC8C_HUMAN
θ value	5.23862e-24 (rank : 33)	NC score	0.668032 (rank : 47)
Query Neighborhood Hits	608	Target Neighborhood Hits	255	Shared Neighborhood Hits	219
SwissProt Accessions	Q8TDW0, Q9H075	Gene names	LRRC8C, AD158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

LRC8D_HUMAN
θ value	5.23862e-24 (rank : 34)	NC score	0.697191 (rank : 27)
Query Neighborhood Hits	608	Target Neighborhood Hits	282	Shared Neighborhood Hits	238
SwissProt Accessions	Q7L1W4, Q6UWB2, Q9NVW3	Gene names	LRRC8D, LRRC5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

RSU1_HUMAN
θ value	2.59989e-23 (rank : 35)	NC score	0.745949 (rank : 15)
Query Neighborhood Hits	608	Target Neighborhood Hits	250	Shared Neighborhood Hits	229
SwissProt Accessions	Q15404	Gene names	RSU1, RSP1
Domain Architecture
Description	Ras suppressor protein 1 (Rsu-1) (RSP-1).

LRC39_MOUSE
θ value	4.43474e-23 (rank : 36)	NC score	0.751155 (rank : 13)
Query Neighborhood Hits	608	Target Neighborhood Hits	269	Shared Neighborhood Hits	227
SwissProt Accessions	Q8BGI7	Gene names	Lrrc39
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 39.

PHLPL_MOUSE
θ value	4.43474e-23 (rank : 37)	NC score	0.695033 (rank : 30)
Query Neighborhood Hits	608	Target Neighborhood Hits	303	Shared Neighborhood Hits	238
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

PHLPP_HUMAN
θ value	4.43474e-23 (rank : 38)	NC score	0.682778 (rank : 42)
Query Neighborhood Hits	608	Target Neighborhood Hits	604	Shared Neighborhood Hits	274
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

RSU1_MOUSE
θ value	4.43474e-23 (rank : 39)	NC score	0.745274 (rank : 16)
Query Neighborhood Hits	608	Target Neighborhood Hits	239	Shared Neighborhood Hits	224
SwissProt Accessions	Q01730	Gene names	Rsu1, Rsp1
Domain Architecture	No domain graphic available
Description	Ras suppressor protein 1 (Rsu-1) (RSP-1).

LRC8C_MOUSE
θ value	7.56453e-23 (rank : 40)	NC score	0.660112 (rank : 54)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	213
SwissProt Accessions	Q8R502, Q3TEP9, Q8C296, Q8R0N7, Q8R3G5	Gene names	Lrrc8c, Ad158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

LRC8B_MOUSE
θ value	2.87452e-22 (rank : 41)	NC score	0.686868 (rank : 37)
Query Neighborhood Hits	608	Target Neighborhood Hits	283	Shared Neighborhood Hits	233
SwissProt Accessions	Q5DU41	Gene names	Lrrc8b, Kiaa0231
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8B.

PHLPL_HUMAN
θ value	4.9032e-22 (rank : 42)	NC score	0.694237 (rank : 31)
Query Neighborhood Hits	608	Target Neighborhood Hits	310	Shared Neighborhood Hits	240
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

LRC8E_HUMAN
θ value	8.36355e-22 (rank : 43)	NC score	0.683028 (rank : 41)
Query Neighborhood Hits	608	Target Neighborhood Hits	259	Shared Neighborhood Hits	232
SwissProt Accessions	Q6NSJ5, Q2YDY3, Q7L236, Q8N3B0, Q9H5H8	Gene names	LRRC8E
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

PHLPP_MOUSE
θ value	1.86321e-21 (rank : 44)	NC score	0.686075 (rank : 38)
Query Neighborhood Hits	608	Target Neighborhood Hits	394	Shared Neighborhood Hits	252
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

LNX1_HUMAN
θ value	2.43343e-21 (rank : 45)	NC score	0.472568 (rank : 236)
Query Neighborhood Hits	608	Target Neighborhood Hits	379	Shared Neighborhood Hits	174
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LRC15_MOUSE
θ value	2.43343e-21 (rank : 46)	NC score	0.672726 (rank : 44)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	242
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

PIDD_HUMAN
θ value	4.15078e-21 (rank : 47)	NC score	0.703375 (rank : 25)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	219
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

PIDD_MOUSE
θ value	9.24701e-21 (rank : 48)	NC score	0.706144 (rank : 24)
Query Neighborhood Hits	608	Target Neighborhood Hits	256	Shared Neighborhood Hits	218
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

LNX1_MOUSE
θ value	1.2077e-20 (rank : 49)	NC score	0.474769 (rank : 233)
Query Neighborhood Hits	608	Target Neighborhood Hits	377	Shared Neighborhood Hits	182
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LRC15_HUMAN
θ value	4.58923e-20 (rank : 50)	NC score	0.667147 (rank : 50)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	243
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

LRCH4_HUMAN
θ value	4.58923e-20 (rank : 51)	NC score	0.691127 (rank : 33)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	231
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

LRCH4_MOUSE
θ value	4.58923e-20 (rank : 52)	NC score	0.687922 (rank : 35)
Query Neighborhood Hits	608	Target Neighborhood Hits	302	Shared Neighborhood Hits	225
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

LRC8E_MOUSE
θ value	1.74391e-19 (rank : 53)	NC score	0.667222 (rank : 48)
Query Neighborhood Hits	608	Target Neighborhood Hits	256	Shared Neighborhood Hits	232
SwissProt Accessions	Q66JT1	Gene names	Lrrc8e
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

LNX2_MOUSE
θ value	2.97466e-19 (rank : 54)	NC score	0.484708 (rank : 223)
Query Neighborhood Hits	608	Target Neighborhood Hits	407	Shared Neighborhood Hits	185
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LRRC2_MOUSE
θ value	5.07402e-19 (rank : 55)	NC score	0.712152 (rank : 21)
Query Neighborhood Hits	608	Target Neighborhood Hits	238	Shared Neighborhood Hits	216
SwissProt Accessions	Q8VDB8, Q9CX04	Gene names	Lrrc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 2.

PZRN4_HUMAN
θ value	5.07402e-19 (rank : 56)	NC score	0.423630 (rank : 278)
Query Neighborhood Hits	608	Target Neighborhood Hits	438	Shared Neighborhood Hits	165
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PTN13_HUMAN
θ value	1.13037e-18 (rank : 57)	NC score	0.301024 (rank : 336)
Query Neighborhood Hits	608	Target Neighborhood Hits	471	Shared Neighborhood Hits	197
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

LRCH1_HUMAN
θ value	7.32683e-18 (rank : 58)	NC score	0.649516 (rank : 62)
Query Neighborhood Hits	608	Target Neighborhood Hits	266	Shared Neighborhood Hits	199
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

LRCH2_HUMAN
θ value	7.32683e-18 (rank : 59)	NC score	0.635797 (rank : 72)
Query Neighborhood Hits	608	Target Neighborhood Hits	315	Shared Neighborhood Hits	202
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRC10_MOUSE
θ value	9.56915e-18 (rank : 60)	NC score	0.702812 (rank : 26)
Query Neighborhood Hits	608	Target Neighborhood Hits	191	Shared Neighborhood Hits	184
SwissProt Accessions	Q8K3W2, Q8BUL2	Gene names	Lrrc10, Hrlrrp
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 10 (Heart-restricted leucine- rich repeat protein).

LRCH2_MOUSE
θ value	9.56915e-18 (rank : 61)	NC score	0.637297 (rank : 71)
Query Neighborhood Hits	608	Target Neighborhood Hits	287	Shared Neighborhood Hits	207
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRRC2_HUMAN
θ value	9.56915e-18 (rank : 62)	NC score	0.721631 (rank : 19)
Query Neighborhood Hits	608	Target Neighborhood Hits	229	Shared Neighborhood Hits	214
SwissProt Accessions	Q9BYS8, Q96LT5	Gene names	LRRC2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 2.

LRCH3_HUMAN
θ value	1.24977e-17 (rank : 63)	NC score	0.656408 (rank : 57)
Query Neighborhood Hits	608	Target Neighborhood Hits	270	Shared Neighborhood Hits	210
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRRK2_HUMAN
θ value	1.24977e-17 (rank : 64)	NC score	0.296003 (rank : 342)
Query Neighborhood Hits	608	Target Neighborhood Hits	1382	Shared Neighborhood Hits	255
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

CPN2_HUMAN
θ value	3.63628e-17 (rank : 65)	NC score	0.657713 (rank : 55)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	233
SwissProt Accessions	P22792, Q86SU4, Q8N5V4	Gene names	CPN2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

GRIP2_HUMAN
θ value	3.63628e-17 (rank : 66)	NC score	0.500607 (rank : 203)
Query Neighborhood Hits	608	Target Neighborhood Hits	256	Shared Neighborhood Hits	204
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

LRCH3_MOUSE
θ value	4.74913e-17 (rank : 67)	NC score	0.647413 (rank : 63)
Query Neighborhood Hits	608	Target Neighborhood Hits	257	Shared Neighborhood Hits	203
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

PZRN3_MOUSE
θ value	4.74913e-17 (rank : 68)	NC score	0.411829 (rank : 284)
Query Neighborhood Hits	608	Target Neighborhood Hits	447	Shared Neighborhood Hits	163
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LGR5_HUMAN
θ value	6.20254e-17 (rank : 69)	NC score	0.633602 (rank : 74)
Query Neighborhood Hits	608	Target Neighborhood Hits	452	Shared Neighborhood Hits	241
SwissProt Accessions	O75473, Q9UP75	Gene names	LGR5, GPR49, GPR67
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67).

LRC10_HUMAN
θ value	8.10077e-17 (rank : 70)	NC score	0.706604 (rank : 23)
Query Neighborhood Hits	608	Target Neighborhood Hits	200	Shared Neighborhood Hits	191
SwissProt Accessions	Q5BKY1, Q6ZVY4	Gene names	LRRC10
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 10.

LRC57_HUMAN
θ value	8.10077e-17 (rank : 71)	NC score	0.743636 (rank : 17)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N9N7, Q7Z2Z6, Q8N1T6	Gene names	LRRC57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

CPN2_MOUSE
θ value	1.058e-16 (rank : 72)	NC score	0.660509 (rank : 53)
Query Neighborhood Hits	608	Target Neighborhood Hits	291	Shared Neighborhood Hits	239
SwissProt Accessions	Q9DBB9, Q8R113	Gene names	Cpn2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

LRRK2_MOUSE
θ value	1.38178e-16 (rank : 73)	NC score	0.309714 (rank : 326)
Query Neighborhood Hits	608	Target Neighborhood Hits	1359	Shared Neighborhood Hits	249
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

LRCH1_MOUSE
θ value	1.80466e-16 (rank : 74)	NC score	0.643137 (rank : 66)
Query Neighborhood Hits	608	Target Neighborhood Hits	264	Shared Neighborhood Hits	201
SwissProt Accessions	P62046	Gene names	Lrch1, Chdc1, Kiaa1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1).

LRTM1_HUMAN
θ value	2.35696e-16 (rank : 75)	NC score	0.627894 (rank : 86)
Query Neighborhood Hits	608	Target Neighborhood Hits	273	Shared Neighborhood Hits	238
SwissProt Accessions	Q86UE6, Q96DN1	Gene names	LRRTM1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

MAGI1_HUMAN
θ value	2.35696e-16 (rank : 76)	NC score	0.455530 (rank : 251)
Query Neighborhood Hits	608	Target Neighborhood Hits	388	Shared Neighborhood Hits	213
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

ALS_HUMAN
θ value	3.07829e-16 (rank : 77)	NC score	0.652517 (rank : 61)
Query Neighborhood Hits	608	Target Neighborhood Hits	280	Shared Neighborhood Hits	238
SwissProt Accessions	P35858	Gene names	IGFALS, ALS
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

LRC57_MOUSE
θ value	3.07829e-16 (rank : 78)	NC score	0.742744 (rank : 18)
Query Neighborhood Hits	608	Target Neighborhood Hits	267	Shared Neighborhood Hits	236
SwissProt Accessions	Q9D1G5, Q9DC95	Gene names	Lrrc57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

GPV_HUMAN
θ value	4.02038e-16 (rank : 79)	NC score	0.670220 (rank : 46)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	239
SwissProt Accessions	P40197	Gene names	GP5
Domain Architecture
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

PZRN3_HUMAN
θ value	4.02038e-16 (rank : 80)	NC score	0.410745 (rank : 285)
Query Neighborhood Hits	608	Target Neighborhood Hits	461	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LNX2_HUMAN
θ value	5.25075e-16 (rank : 81)	NC score	0.468273 (rank : 241)
Query Neighborhood Hits	608	Target Neighborhood Hits	389	Shared Neighborhood Hits	183
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LRRK1_MOUSE
θ value	5.25075e-16 (rank : 82)	NC score	0.305686 (rank : 330)
Query Neighborhood Hits	608	Target Neighborhood Hits	1267	Shared Neighborhood Hits	254
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

VASN_MOUSE
θ value	5.25075e-16 (rank : 83)	NC score	0.628147 (rank : 85)
Query Neighborhood Hits	608	Target Neighborhood Hits	426	Shared Neighborhood Hits	240
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

PTN13_MOUSE
θ value	6.85773e-16 (rank : 84)	NC score	0.295338 (rank : 346)
Query Neighborhood Hits	608	Target Neighborhood Hits	426	Shared Neighborhood Hits	196
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

LRTM2_HUMAN
θ value	8.95645e-16 (rank : 85)	NC score	0.628621 (rank : 82)
Query Neighborhood Hits	608	Target Neighborhood Hits	282	Shared Neighborhood Hits	232
SwissProt Accessions	O43300, Q7L770	Gene names	LRRTM2, KIAA0416, LRRN2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor (Leucine-rich repeat neuronal 2 protein).

LGR5_MOUSE
θ value	1.16975e-15 (rank : 86)	NC score	0.628150 (rank : 84)
Query Neighborhood Hits	608	Target Neighborhood Hits	484	Shared Neighborhood Hits	242
SwissProt Accessions	Q9Z1P4	Gene names	Lgr5, Fex, Gpr49
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX).

LRTM2_MOUSE
θ value	1.16975e-15 (rank : 87)	NC score	0.629676 (rank : 78)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	231
SwissProt Accessions	Q8BGA3, Q80U08	Gene names	Lrrtm2, Kiaa0416
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor.

GRIP1_HUMAN
θ value	1.99529e-15 (rank : 88)	NC score	0.492708 (rank : 213)
Query Neighborhood Hits	608	Target Neighborhood Hits	231	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

LGR4_HUMAN
θ value	1.99529e-15 (rank : 89)	NC score	0.630204 (rank : 76)
Query Neighborhood Hits	608	Target Neighborhood Hits	481	Shared Neighborhood Hits	240
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

LRC32_HUMAN
θ value	1.99529e-15 (rank : 90)	NC score	0.657483 (rank : 56)
Query Neighborhood Hits	608	Target Neighborhood Hits	303	Shared Neighborhood Hits	243
SwissProt Accessions	Q14392, Q86V06	Gene names	LRRC32, GARP
Domain Architecture
Description	Leucine-rich repeat-containing protein 32 precursor (GARP protein) (Garpin) (Glycoprotein A repetitions predominant).

LRTM1_MOUSE
θ value	1.99529e-15 (rank : 91)	NC score	0.613328 (rank : 98)
Query Neighborhood Hits	608	Target Neighborhood Hits	264	Shared Neighborhood Hits	230
SwissProt Accessions	Q8K377, Q3UVX1	Gene names	Lrrtm1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

VASN_HUMAN
θ value	1.99529e-15 (rank : 92)	NC score	0.622058 (rank : 91)
Query Neighborhood Hits	608	Target Neighborhood Hits	449	Shared Neighborhood Hits	234
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

PAR3L_HUMAN
θ value	2.60593e-15 (rank : 93)	NC score	0.488508 (rank : 220)
Query Neighborhood Hits	608	Target Neighborhood Hits	297	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDZD1_MOUSE
θ value	2.60593e-15 (rank : 94)	NC score	0.488094 (rank : 221)
Query Neighborhood Hits	608	Target Neighborhood Hits	191	Shared Neighborhood Hits	170
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LRRK1_HUMAN
θ value	3.40345e-15 (rank : 95)	NC score	0.303683 (rank : 333)
Query Neighborhood Hits	608	Target Neighborhood Hits	1237	Shared Neighborhood Hits	246
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

GRIP1_MOUSE
θ value	4.44505e-15 (rank : 96)	NC score	0.491696 (rank : 214)
Query Neighborhood Hits	608	Target Neighborhood Hits	241	Shared Neighborhood Hits	198
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

LRIG3_MOUSE
θ value	4.44505e-15 (rank : 97)	NC score	0.502716 (rank : 201)
Query Neighborhood Hits	608	Target Neighborhood Hits	611	Shared Neighborhood Hits	246
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

MAGI1_MOUSE
θ value	7.58209e-15 (rank : 98)	NC score	0.450594 (rank : 253)
Query Neighborhood Hits	608	Target Neighborhood Hits	403	Shared Neighborhood Hits	213
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PARD3_MOUSE
θ value	7.58209e-15 (rank : 99)	NC score	0.479105 (rank : 231)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	176
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

FLRT3_HUMAN
θ value	9.90251e-15 (rank : 100)	NC score	0.610794 (rank : 100)
Query Neighborhood Hits	608	Target Neighborhood Hits	281	Shared Neighborhood Hits	230
SwissProt Accessions	Q9NZU0, Q96K39, Q96K42, Q96KB1, Q9P259	Gene names	FLRT3, KIAA1469
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT3 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 3).

LRC18_HUMAN
θ value	9.90251e-15 (rank : 101)	NC score	0.696938 (rank : 28)
Query Neighborhood Hits	608	Target Neighborhood Hits	217	Shared Neighborhood Hits	199
SwissProt Accessions	Q8N456, Q6UY02	Gene names	LRRC18
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18.

LRC18_MOUSE
θ value	9.90251e-15 (rank : 102)	NC score	0.712112 (rank : 22)
Query Neighborhood Hits	608	Target Neighborhood Hits	224	Shared Neighborhood Hits	207
SwissProt Accessions	Q9CQ07, Q6P8T8, Q80ZT3, Q9CW01, Q9DA89	Gene names	Lrrc18, Mtlr1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18 (Testis-specific LRR protein).

LRIG1_MOUSE
θ value	2.20605e-14 (rank : 103)	NC score	0.479967 (rank : 228)
Query Neighborhood Hits	608	Target Neighborhood Hits	627	Shared Neighborhood Hits	244
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRSM1_HUMAN
θ value	3.76295e-14 (rank : 104)	NC score	0.489020 (rank : 219)
Query Neighborhood Hits	608	Target Neighborhood Hits	1078	Shared Neighborhood Hits	229
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PARD3_HUMAN
θ value	3.76295e-14 (rank : 105)	NC score	0.479579 (rank : 229)
Query Neighborhood Hits	608	Target Neighborhood Hits	312	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDZD7_HUMAN
θ value	3.76295e-14 (rank : 106)	NC score	0.524512 (rank : 156)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	175
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PGS2_MOUSE
θ value	3.76295e-14 (rank : 107)	NC score	0.618637 (rank : 94)
Query Neighborhood Hits	608	Target Neighborhood Hits	285	Shared Neighborhood Hits	239
SwissProt Accessions	P28654	Gene names	Dcn
Domain Architecture
Description	Decorin precursor (Bone proteoglycan II) (PG-S2) (PG40).

PDZD1_HUMAN
θ value	4.91457e-14 (rank : 108)	NC score	0.476261 (rank : 232)
Query Neighborhood Hits	608	Target Neighborhood Hits	190	Shared Neighborhood Hits	169
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LRIG3_HUMAN
θ value	6.41864e-14 (rank : 109)	NC score	0.506054 (rank : 192)
Query Neighborhood Hits	608	Target Neighborhood Hits	601	Shared Neighborhood Hits	243
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRTM4_HUMAN
θ value	6.41864e-14 (rank : 110)	NC score	0.584283 (rank : 112)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	227
SwissProt Accessions	Q86VH4	Gene names	LRRTM4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

WHRN_MOUSE
θ value	6.41864e-14 (rank : 111)	NC score	0.498188 (rank : 206)
Query Neighborhood Hits	608	Target Neighborhood Hits	412	Shared Neighborhood Hits	214
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

LRTM4_MOUSE
θ value	8.38298e-14 (rank : 112)	NC score	0.584438 (rank : 111)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	229
SwissProt Accessions	Q80XG9, Q8C030, Q8JZS8	Gene names	Lrrtm4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

A2GL_HUMAN
θ value	1.09485e-13 (rank : 113)	NC score	0.661039 (rank : 52)
Query Neighborhood Hits	608	Target Neighborhood Hits	281	Shared Neighborhood Hits	238
SwissProt Accessions	P02750, Q8N4F5, Q96QZ4	Gene names	LRG1, LRG
Domain Architecture
Description	Leucine-rich alpha-2-glycoprotein precursor (LRG).

PDZD2_HUMAN
θ value	1.09485e-13 (rank : 114)	NC score	0.470082 (rank : 240)
Query Neighborhood Hits	608	Target Neighborhood Hits	772	Shared Neighborhood Hits	227
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

ALS_MOUSE
θ value	1.42992e-13 (rank : 115)	NC score	0.640798 (rank : 68)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	235
SwissProt Accessions	P70389, Q9DBI7	Gene names	Igfals, Albs, Als
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

LRC47_MOUSE
θ value	1.42992e-13 (rank : 116)	NC score	0.670917 (rank : 45)
Query Neighborhood Hits	608	Target Neighborhood Hits	299	Shared Neighborhood Hits	229
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LRSM1_MOUSE
θ value	1.42992e-13 (rank : 117)	NC score	0.526599 (rank : 153)
Query Neighborhood Hits	608	Target Neighborhood Hits	874	Shared Neighborhood Hits	221
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

PRELP_HUMAN
θ value	1.42992e-13 (rank : 118)	NC score	0.628276 (rank : 83)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	239
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

WHRN_HUMAN
θ value	1.42992e-13 (rank : 119)	NC score	0.501145 (rank : 202)
Query Neighborhood Hits	608	Target Neighborhood Hits	325	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

LRC47_HUMAN
θ value	2.43908e-13 (rank : 120)	NC score	0.667151 (rank : 49)
Query Neighborhood Hits	608	Target Neighborhood Hits	300	Shared Neighborhood Hits	230
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

PGS1_MOUSE
θ value	2.43908e-13 (rank : 121)	NC score	0.603758 (rank : 102)
Query Neighborhood Hits	608	Target Neighborhood Hits	265	Shared Neighborhood Hits	227
SwissProt Accessions	P28653, Q61355	Gene names	Bgn
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

USH1C_HUMAN
θ value	2.43908e-13 (rank : 122)	NC score	0.518844 (rank : 172)
Query Neighborhood Hits	608	Target Neighborhood Hits	327	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

LLR1_HUMAN
θ value	4.16044e-13 (rank : 123)	NC score	0.720103 (rank : 20)
Query Neighborhood Hits	608	Target Neighborhood Hits	225	Shared Neighborhood Hits	205
SwissProt Accessions	Q96L50, Q86SZ1, Q8N6H9	Gene names	PPIL5, LRR1
Domain Architecture
Description	Peptidylprolyl isomerase-like 5 (LRR-repeat protein 1) (LRR-1) (4-1BB- mediated signaling molecule) (4-1BBlrr).

PGS1_HUMAN
θ value	4.16044e-13 (rank : 124)	NC score	0.598740 (rank : 106)
Query Neighborhood Hits	608	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	P21810, P13247	Gene names	BGN
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

PDZD3_HUMAN
θ value	5.43371e-13 (rank : 125)	NC score	0.448100 (rank : 257)
Query Neighborhood Hits	608	Target Neighborhood Hits	180	Shared Neighborhood Hits	172
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

LRIG1_HUMAN
θ value	7.09661e-13 (rank : 126)	NC score	0.461224 (rank : 244)
Query Neighborhood Hits	608	Target Neighborhood Hits	654	Shared Neighborhood Hits	248
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LGR6_HUMAN
θ value	1.2105e-12 (rank : 127)	NC score	0.645138 (rank : 64)
Query Neighborhood Hits	608	Target Neighborhood Hits	344	Shared Neighborhood Hits	240
SwissProt Accessions	Q9HBX8, Q5T509, Q5T512, Q6UY15, Q86VU0, Q96K69, Q9BYD7	Gene names	LGR6
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 6 (VTS20631).

FLRT1_HUMAN
θ value	3.52202e-12 (rank : 128)	NC score	0.622733 (rank : 89)
Query Neighborhood Hits	608	Target Neighborhood Hits	286	Shared Neighborhood Hits	229
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

SYJ2B_HUMAN
θ value	3.52202e-12 (rank : 129)	NC score	0.562587 (rank : 121)
Query Neighborhood Hits	608	Target Neighborhood Hits	162	Shared Neighborhood Hits	161
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

ECM2_HUMAN
θ value	4.59992e-12 (rank : 130)	NC score	0.633963 (rank : 73)
Query Neighborhood Hits	608	Target Neighborhood Hits	402	Shared Neighborhood Hits	252
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

ZO1_MOUSE
θ value	4.59992e-12 (rank : 131)	NC score	0.410018 (rank : 286)
Query Neighborhood Hits	608	Target Neighborhood Hits	453	Shared Neighborhood Hits	202
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ASPN_MOUSE
θ value	6.00763e-12 (rank : 132)	NC score	0.599093 (rank : 105)
Query Neighborhood Hits	608	Target Neighborhood Hits	277	Shared Neighborhood Hits	238
SwissProt Accessions	Q99MQ4, Q9D6A2	Gene names	Aspn
Domain Architecture
Description	Asporin precursor.

USH1C_MOUSE
θ value	6.00763e-12 (rank : 133)	NC score	0.481917 (rank : 226)
Query Neighborhood Hits	608	Target Neighborhood Hits	557	Shared Neighborhood Hits	217
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

FLRT2_HUMAN
θ value	1.02475e-11 (rank : 134)	NC score	0.591585 (rank : 108)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	227
SwissProt Accessions	O43155	Gene names	FLRT2, KIAA0405
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT2 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 2).

ASPN_HUMAN
θ value	1.33837e-11 (rank : 135)	NC score	0.606810 (rank : 101)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	239
SwissProt Accessions	Q9BXN1, Q96K79, Q96LD0, Q9NXP3	Gene names	ASPN, PLAP1
Domain Architecture
Description	Asporin precursor (Periodontal ligament-associated protein 1) (PLAP- 1).

LRIG2_MOUSE
θ value	1.33837e-11 (rank : 136)	NC score	0.479317 (rank : 230)
Query Neighborhood Hits	608	Target Neighborhood Hits	586	Shared Neighborhood Hits	239
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

ZO1_HUMAN
θ value	2.28291e-11 (rank : 137)	NC score	0.403317 (rank : 291)
Query Neighborhood Hits	608	Target Neighborhood Hits	474	Shared Neighborhood Hits	195
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LRTM3_HUMAN
θ value	2.98157e-11 (rank : 138)	NC score	0.580659 (rank : 114)
Query Neighborhood Hits	608	Target Neighborhood Hits	276	Shared Neighborhood Hits	227
SwissProt Accessions	Q86VH5, Q6N0A3	Gene names	LRRTM3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

PDZD3_MOUSE
θ value	3.89403e-11 (rank : 139)	NC score	0.429904 (rank : 269)
Query Neighborhood Hits	608	Target Neighborhood Hits	171	Shared Neighborhood Hits	168
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

LRIG2_HUMAN
θ value	5.08577e-11 (rank : 140)	NC score	0.472596 (rank : 235)
Query Neighborhood Hits	608	Target Neighborhood Hits	595	Shared Neighborhood Hits	241
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRTM3_MOUSE
θ value	5.08577e-11 (rank : 141)	NC score	0.578975 (rank : 116)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	227
SwissProt Accessions	Q8BZ81, Q3TQA3, Q8BGJ7	Gene names	Lrrtm3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

NGL1_HUMAN
θ value	6.64225e-11 (rank : 142)	NC score	0.551453 (rank : 126)
Query Neighborhood Hits	608	Target Neighborhood Hits	511	Shared Neighborhood Hits	236
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
θ value	6.64225e-11 (rank : 143)	NC score	0.551609 (rank : 125)
Query Neighborhood Hits	608	Target Neighborhood Hits	512	Shared Neighborhood Hits	236
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NHRF2_HUMAN
θ value	6.64225e-11 (rank : 144)	NC score	0.450190 (rank : 254)
Query Neighborhood Hits	608	Target Neighborhood Hits	197	Shared Neighborhood Hits	179
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

LRC4B_MOUSE
θ value	8.67504e-11 (rank : 145)	NC score	0.547111 (rank : 134)
Query Neighborhood Hits	608	Target Neighborhood Hits	484	Shared Neighborhood Hits	234
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRC59_MOUSE
θ value	8.67504e-11 (rank : 146)	NC score	0.684954 (rank : 40)
Query Neighborhood Hits	608	Target Neighborhood Hits	415	Shared Neighborhood Hits	235
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

FMOD_HUMAN
θ value	1.133e-10 (rank : 147)	NC score	0.630349 (rank : 75)
Query Neighborhood Hits	608	Target Neighborhood Hits	283	Shared Neighborhood Hits	239
SwissProt Accessions	Q06828, Q15331	Gene names	FMOD, FM
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

PP1R7_HUMAN
θ value	1.133e-10 (rank : 148)	NC score	0.612544 (rank : 99)
Query Neighborhood Hits	608	Target Neighborhood Hits	265	Shared Neighborhood Hits	207
SwissProt Accessions	Q15435, Q9UQE5, Q9UQE6, Q9Y6K4	Gene names	PPP1R7, SDS22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

R4RL2_HUMAN
θ value	1.133e-10 (rank : 149)	NC score	0.554678 (rank : 123)
Query Neighborhood Hits	608	Target Neighborhood Hits	273	Shared Neighborhood Hits	227
SwissProt Accessions	Q86UN3, Q6X813	Gene names	RTN4RL2, NGRH1, NGRL3
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 2 precursor (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2) (Nogo receptor-like 3).

R4RL2_MOUSE
θ value	1.133e-10 (rank : 150)	NC score	0.548730 (rank : 131)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	227
SwissProt Accessions	Q7M6Z0, Q3UQ62	Gene names	Rtn4rl2, Ngrl3
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 2 precursor (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2) (Nogo receptor-like 3).

SLIT2_HUMAN
θ value	1.133e-10 (rank : 151)	NC score	0.414271 (rank : 282)
Query Neighborhood Hits	608	Target Neighborhood Hits	708	Shared Neighborhood Hits	242
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	1.133e-10 (rank : 152)	NC score	0.417883 (rank : 280)
Query Neighborhood Hits	608	Target Neighborhood Hits	684	Shared Neighborhood Hits	243
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LIN7A_HUMAN
θ value	1.47974e-10 (rank : 153)	NC score	0.511542 (rank : 182)
Query Neighborhood Hits	608	Target Neighborhood Hits	193	Shared Neighborhood Hits	188
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	1.47974e-10 (rank : 154)	NC score	0.511632 (rank : 181)
Query Neighborhood Hits	608	Target Neighborhood Hits	193	Shared Neighborhood Hits	188
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LRC59_HUMAN
θ value	1.47974e-10 (rank : 155)	NC score	0.685422 (rank : 39)
Query Neighborhood Hits	608	Target Neighborhood Hits	398	Shared Neighborhood Hits	233
SwissProt Accessions	Q96AG4, Q9P189	Gene names	LRRC59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

LIN7B_HUMAN
θ value	1.9326e-10 (rank : 156)	NC score	0.513738 (rank : 178)
Query Neighborhood Hits	608	Target Neighborhood Hits	200	Shared Neighborhood Hits	190
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7C_HUMAN
θ value	1.9326e-10 (rank : 157)	NC score	0.509330 (rank : 186)
Query Neighborhood Hits	608	Target Neighborhood Hits	198	Shared Neighborhood Hits	190
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	1.9326e-10 (rank : 158)	NC score	0.509330 (rank : 187)
Query Neighborhood Hits	608	Target Neighborhood Hits	198	Shared Neighborhood Hits	190
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

NHERF_MOUSE
θ value	1.9326e-10 (rank : 159)	NC score	0.459249 (rank : 246)
Query Neighborhood Hits	608	Target Neighborhood Hits	195	Shared Neighborhood Hits	172
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

IL16_HUMAN
θ value	2.52405e-10 (rank : 160)	NC score	0.457384 (rank : 249)
Query Neighborhood Hits	608	Target Neighborhood Hits	207	Shared Neighborhood Hits	152
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LIN7B_MOUSE
θ value	2.52405e-10 (rank : 161)	NC score	0.511890 (rank : 180)
Query Neighborhood Hits	608	Target Neighborhood Hits	200	Shared Neighborhood Hits	190
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LRC4B_HUMAN
θ value	2.52405e-10 (rank : 162)	NC score	0.545589 (rank : 139)
Query Neighborhood Hits	608	Target Neighborhood Hits	479	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

CNOT6_MOUSE
θ value	4.30538e-10 (rank : 163)	NC score	0.622924 (rank : 88)
Query Neighborhood Hits	608	Target Neighborhood Hits	229	Shared Neighborhood Hits	210
SwissProt Accessions	Q8K3P5, Q5NCL3, Q80V15	Gene names	Cnot6, Ccr4, Kiaa1194
Domain Architecture
Description	CCR4-NOT transcription complex subunit 6 (EC 3.1.-.-) (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4 homolog) (CCR4 carbon catabolite repression 4-like).

FMOD_MOUSE
θ value	4.30538e-10 (rank : 164)	NC score	0.638395 (rank : 70)
Query Neighborhood Hits	608	Target Neighborhood Hits	286	Shared Neighborhood Hits	238
SwissProt Accessions	P50608	Gene names	Fmod
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

MAGI2_HUMAN
θ value	4.30538e-10 (rank : 165)	NC score	0.430366 (rank : 268)
Query Neighborhood Hits	608	Target Neighborhood Hits	373	Shared Neighborhood Hits	208
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

CNOT6_HUMAN
θ value	5.62301e-10 (rank : 166)	NC score	0.614991 (rank : 97)
Query Neighborhood Hits	608	Target Neighborhood Hits	225	Shared Neighborhood Hits	207
SwissProt Accessions	Q9ULM6	Gene names	CNOT6, CCR4, KIAA1194
Domain Architecture
Description	CCR4-NOT transcription complex subunit 6 (EC 3.1.-.-) (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4 homolog) (CCR4 carbon catabolite repression 4-like).

LRFN4_HUMAN
θ value	7.34386e-10 (rank : 167)	NC score	0.503657 (rank : 200)
Query Neighborhood Hits	608	Target Neighborhood Hits	462	Shared Neighborhood Hits	229
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRC33_MOUSE
θ value	1.25267e-09 (rank : 168)	NC score	0.629251 (rank : 80)
Query Neighborhood Hits	608	Target Neighborhood Hits	296	Shared Neighborhood Hits	241
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

PGS2_HUMAN
θ value	1.25267e-09 (rank : 169)	NC score	0.580241 (rank : 115)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	233
SwissProt Accessions	P07585, Q9P0Z0, Q9P0Z1, Q9Y5N8, Q9Y5N9	Gene names	DCN
Domain Architecture
Description	Decorin precursor (Bone proteoglycan II) (PG-S2) (PG40).

TLR5_MOUSE
θ value	1.25267e-09 (rank : 170)	NC score	0.545567 (rank : 140)
Query Neighborhood Hits	608	Target Neighborhood Hits	287	Shared Neighborhood Hits	227
SwissProt Accessions	Q9JLF7	Gene names	Tlr5
Domain Architecture
Description	Toll-like receptor 5 precursor.

LUM_HUMAN
θ value	1.63604e-09 (rank : 171)	NC score	0.619962 (rank : 93)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	238
SwissProt Accessions	P51884, Q96QM7	Gene names	LUM, LDC
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

PP1R7_MOUSE
θ value	2.13673e-09 (rank : 172)	NC score	0.600397 (rank : 104)
Query Neighborhood Hits	608	Target Neighborhood Hits	256	Shared Neighborhood Hits	205
SwissProt Accessions	Q3UM45, Q9CV31, Q9Z105	Gene names	Ppp1r7, Sds22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

TLR13_MOUSE
θ value	2.13673e-09 (rank : 173)	NC score	0.589774 (rank : 109)
Query Neighborhood Hits	608	Target Neighborhood Hits	335	Shared Neighborhood Hits	241
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

AMGO1_MOUSE
θ value	2.79066e-09 (rank : 174)	NC score	0.546898 (rank : 135)
Query Neighborhood Hits	608	Target Neighborhood Hits	325	Shared Neighborhood Hits	226
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

LRC33_HUMAN
θ value	2.79066e-09 (rank : 175)	NC score	0.622151 (rank : 90)
Query Neighborhood Hits	608	Target Neighborhood Hits	293	Shared Neighborhood Hits	239
SwissProt Accessions	Q86YC3	Gene names	LRRC33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

LRFN4_MOUSE
θ value	2.79066e-09 (rank : 176)	NC score	0.504319 (rank : 195)
Query Neighborhood Hits	608	Target Neighborhood Hits	442	Shared Neighborhood Hits	228
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LUM_MOUSE
θ value	2.79066e-09 (rank : 177)	NC score	0.624380 (rank : 87)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	237
SwissProt Accessions	P51885, Q3TP25, Q99JZ3, Q9CXK0	Gene names	Lum, Lcn, Ldc
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

MAGI2_MOUSE
θ value	2.79066e-09 (rank : 178)	NC score	0.427712 (rank : 273)
Query Neighborhood Hits	608	Target Neighborhood Hits	370	Shared Neighborhood Hits	202
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

NHERF_HUMAN
θ value	2.79066e-09 (rank : 179)	NC score	0.445946 (rank : 259)
Query Neighborhood Hits	608	Target Neighborhood Hits	190	Shared Neighborhood Hits	169
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_MOUSE
θ value	2.79066e-09 (rank : 180)	NC score	0.442328 (rank : 260)
Query Neighborhood Hits	608	Target Neighborhood Hits	194	Shared Neighborhood Hits	178
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PRELP_MOUSE
θ value	2.79066e-09 (rank : 181)	NC score	0.621435 (rank : 92)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	241
SwissProt Accessions	Q9JK53	Gene names	Prelp
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

TSK_MOUSE
θ value	2.79066e-09 (rank : 182)	NC score	0.628752 (rank : 81)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	230
SwissProt Accessions	Q8CBR6, Q4W655	Gene names	Lrrc54, Tsk
Domain Architecture	No domain graphic available
Description	Tsukushi precursor (Leucine-rich repeat-containing protein 54).

TX1B3_HUMAN
θ value	2.79066e-09 (rank : 183)	NC score	0.524075 (rank : 157)
Query Neighborhood Hits	608	Target Neighborhood Hits	161	Shared Neighborhood Hits	156
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	2.79066e-09 (rank : 184)	NC score	0.521591 (rank : 164)
Query Neighborhood Hits	608	Target Neighborhood Hits	158	Shared Neighborhood Hits	153
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

AMGO1_HUMAN
θ value	4.76016e-09 (rank : 185)	NC score	0.545825 (rank : 138)
Query Neighborhood Hits	608	Target Neighborhood Hits	353	Shared Neighborhood Hits	226
SwissProt Accessions	Q86WK6, Q8IW71, Q9ULQ7	Gene names	AMIGO1, ALI2, AMIGO, KIAA1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

LRFN3_HUMAN
θ value	4.76016e-09 (rank : 186)	NC score	0.517180 (rank : 174)
Query Neighborhood Hits	608	Target Neighborhood Hits	444	Shared Neighborhood Hits	233
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
θ value	4.76016e-09 (rank : 187)	NC score	0.512072 (rank : 179)
Query Neighborhood Hits	608	Target Neighborhood Hits	455	Shared Neighborhood Hits	231
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

OMD_MOUSE
θ value	4.76016e-09 (rank : 188)	NC score	0.629278 (rank : 79)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	233
SwissProt Accessions	O35103	Gene names	Omd
Domain Architecture
Description	Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan sulfate proteoglycan osteomodulin) (KSPG osteomodulin).

DLG5_HUMAN
θ value	6.21693e-09 (rank : 189)	NC score	0.311757 (rank : 325)
Query Neighborhood Hits	608	Target Neighborhood Hits	1088	Shared Neighborhood Hits	208
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

LRC20_MOUSE
θ value	1.06045e-08 (rank : 190)	NC score	0.654865 (rank : 58)
Query Neighborhood Hits	608	Target Neighborhood Hits	220	Shared Neighborhood Hits	199
SwissProt Accessions	Q8CI70	Gene names	Lrrc20
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 20.

LRFN2_HUMAN
θ value	1.06045e-08 (rank : 191)	NC score	0.486388 (rank : 222)
Query Neighborhood Hits	608	Target Neighborhood Hits	450	Shared Neighborhood Hits	227
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
θ value	1.06045e-08 (rank : 192)	NC score	0.484166 (rank : 224)
Query Neighborhood Hits	608	Target Neighborhood Hits	450	Shared Neighborhood Hits	225
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

ZO2_HUMAN
θ value	1.38499e-08 (rank : 193)	NC score	0.402593 (rank : 292)
Query Neighborhood Hits	608	Target Neighborhood Hits	289	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

RTN4R_HUMAN
θ value	1.80886e-08 (rank : 194)	NC score	0.546756 (rank : 137)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	225
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

CHAD_MOUSE
θ value	3.08544e-08 (rank : 195)	NC score	0.597877 (rank : 107)
Query Neighborhood Hits	608	Target Neighborhood Hits	260	Shared Neighborhood Hits	226
SwissProt Accessions	O55226	Gene names	Chad
Domain Architecture
Description	Chondroadherin precursor (Cartilage leucine-rich protein).

NYX_HUMAN
θ value	3.08544e-08 (rank : 196)	NC score	0.556024 (rank : 122)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	208
SwissProt Accessions	Q9GZU5, Q5H983, Q9H4J0	Gene names	NYX, CLRP
Domain Architecture
Description	Nyctalopin precursor.

SLIT3_MOUSE
θ value	3.08544e-08 (rank : 197)	NC score	0.424260 (rank : 277)
Query Neighborhood Hits	608	Target Neighborhood Hits	700	Shared Neighborhood Hits	244
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SNTB2_HUMAN
θ value	4.0297e-08 (rank : 198)	NC score	0.406847 (rank : 288)
Query Neighborhood Hits	608	Target Neighborhood Hits	180	Shared Neighborhood Hits	165
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	4.0297e-08 (rank : 199)	NC score	0.405327 (rank : 290)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	165
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

TLR9_MOUSE
θ value	4.0297e-08 (rank : 200)	NC score	0.527296 (rank : 151)
Query Neighborhood Hits	608	Target Neighborhood Hits	291	Shared Neighborhood Hits	233
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LRRN5_HUMAN
θ value	5.26297e-08 (rank : 201)	NC score	0.532806 (rank : 145)
Query Neighborhood Hits	608	Target Neighborhood Hits	493	Shared Neighborhood Hits	234
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

MPP4_HUMAN
θ value	5.26297e-08 (rank : 202)	NC score	0.328307 (rank : 320)
Query Neighborhood Hits	608	Target Neighborhood Hits	205	Shared Neighborhood Hits	140
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

RXFP1_HUMAN
θ value	5.26297e-08 (rank : 203)	NC score	0.498213 (rank : 205)
Query Neighborhood Hits	608	Target Neighborhood Hits	816	Shared Neighborhood Hits	245
SwissProt Accessions	Q9HBX9	Gene names	RXFP1, LGR7
Domain Architecture
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-rich repeat-containing G-protein coupled receptor 7).

LRC27_MOUSE
θ value	6.87365e-08 (rank : 204)	NC score	0.603092 (rank : 103)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	214
SwissProt Accessions	Q80YS5, Q9D6Z2	Gene names	Lrrc27
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

RXFP2_MOUSE
θ value	6.87365e-08 (rank : 205)	NC score	0.523588 (rank : 160)
Query Neighborhood Hits	608	Target Neighborhood Hits	760	Shared Neighborhood Hits	232
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

SNTA1_HUMAN
θ value	6.87365e-08 (rank : 206)	NC score	0.390512 (rank : 299)
Query Neighborhood Hits	608	Target Neighborhood Hits	186	Shared Neighborhood Hits	170
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

TLR5_HUMAN
θ value	6.87365e-08 (rank : 207)	NC score	0.552149 (rank : 124)
Query Neighborhood Hits	608	Target Neighborhood Hits	288	Shared Neighborhood Hits	228
SwissProt Accessions	O60602, O15456	Gene names	TLR5, TIL3
Domain Architecture
Description	Toll-like receptor 5 precursor (Toll/interleukin-1 receptor-like protein 3).

NFH_MOUSE
θ value	8.97725e-08 (rank : 208)	NC score	0.022910 (rank : 525)
Query Neighborhood Hits	608	Target Neighborhood Hits	2247	Shared Neighborhood Hits	131
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RXFP2_HUMAN
θ value	8.97725e-08 (rank : 209)	NC score	0.505113 (rank : 193)
Query Neighborhood Hits	608	Target Neighborhood Hits	736	Shared Neighborhood Hits	234
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

SLIT3_HUMAN
θ value	8.97725e-08 (rank : 210)	NC score	0.425017 (rank : 275)
Query Neighborhood Hits	608	Target Neighborhood Hits	682	Shared Neighborhood Hits	243
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

OMD_HUMAN
θ value	1.17247e-07 (rank : 211)	NC score	0.615643 (rank : 96)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	234
SwissProt Accessions	Q99983	Gene names	OMD
Domain Architecture
Description	Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan sulfate proteoglycan osteomodulin) (KSPG osteomodulin).

PDZ11_HUMAN
θ value	1.17247e-07 (rank : 212)	NC score	0.498181 (rank : 207)
Query Neighborhood Hits	608	Target Neighborhood Hits	160	Shared Neighborhood Hits	155
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	1.17247e-07 (rank : 213)	NC score	0.495445 (rank : 212)
Query Neighborhood Hits	608	Target Neighborhood Hits	154	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SLIK2_MOUSE
θ value	1.17247e-07 (rank : 214)	NC score	0.504940 (rank : 194)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	235
SwissProt Accessions	Q810C0, Q8BXL6	Gene names	Slitrk2
Domain Architecture
Description	SLIT and NTRK-like protein 2 precursor.

SNTB1_HUMAN
θ value	1.17247e-07 (rank : 215)	NC score	0.377528 (rank : 305)
Query Neighborhood Hits	608	Target Neighborhood Hits	157	Shared Neighborhood Hits	152
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	1.17247e-07 (rank : 216)	NC score	0.376789 (rank : 306)
Query Neighborhood Hits	608	Target Neighborhood Hits	160	Shared Neighborhood Hits	151
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

TSK_HUMAN
θ value	1.17247e-07 (rank : 217)	NC score	0.616836 (rank : 95)
Query Neighborhood Hits	608	Target Neighborhood Hits	268	Shared Neighborhood Hits	230
SwissProt Accessions	Q8WUA8, Q6UXK1, Q9UG10, Q9UJX9	Gene names	LRRC54, E2IG4, TSK
Domain Architecture	No domain graphic available
Description	Tsukushi precursor (Leucine-rich repeat-containing protein 54) (E2- induced gene 4 protein).

GOPC_HUMAN
θ value	1.53129e-07 (rank : 218)	NC score	0.426947 (rank : 274)
Query Neighborhood Hits	608	Target Neighborhood Hits	377	Shared Neighborhood Hits	179
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	1.53129e-07 (rank : 219)	NC score	0.433718 (rank : 267)
Query Neighborhood Hits	608	Target Neighborhood Hits	323	Shared Neighborhood Hits	178
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

NYX_MOUSE
θ value	1.53129e-07 (rank : 220)	NC score	0.548868 (rank : 129)
Query Neighborhood Hits	608	Target Neighborhood Hits	241	Shared Neighborhood Hits	207
SwissProt Accessions	P83503, Q8BYN4	Gene names	Nyx
Domain Architecture
Description	Nyctalopin precursor.

SLIT1_HUMAN
θ value	1.53129e-07 (rank : 221)	NC score	0.402155 (rank : 293)
Query Neighborhood Hits	608	Target Neighborhood Hits	700	Shared Neighborhood Hits	243
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SNTG1_MOUSE
θ value	1.53129e-07 (rank : 222)	NC score	0.391363 (rank : 297)
Query Neighborhood Hits	608	Target Neighborhood Hits	179	Shared Neighborhood Hits	173
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

NEB2_HUMAN
θ value	1.99992e-07 (rank : 223)	NC score	0.267433 (rank : 371)
Query Neighborhood Hits	608	Target Neighborhood Hits	883	Shared Neighborhood Hits	150
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	1.99992e-07 (rank : 224)	NC score	0.264656 (rank : 373)
Query Neighborhood Hits	608	Target Neighborhood Hits	889	Shared Neighborhood Hits	151
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SNTG1_HUMAN
θ value	1.99992e-07 (rank : 225)	NC score	0.391243 (rank : 298)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

LRRN1_MOUSE
θ value	2.61198e-07 (rank : 226)	NC score	0.544054 (rank : 141)
Query Neighborhood Hits	608	Target Neighborhood Hits	508	Shared Neighborhood Hits	231
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

ZO3_MOUSE
θ value	2.61198e-07 (rank : 227)	NC score	0.424521 (rank : 276)
Query Neighborhood Hits	608	Target Neighborhood Hits	224	Shared Neighborhood Hits	188
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

CHAD_HUMAN
θ value	3.41135e-07 (rank : 228)	NC score	0.588343 (rank : 110)
Query Neighborhood Hits	608	Target Neighborhood Hits	267	Shared Neighborhood Hits	231
SwissProt Accessions	O15335, Q96RJ5	Gene names	CHAD
Domain Architecture
Description	Chondroadherin precursor (Cartilage leucine-rich protein).

LRC20_HUMAN
θ value	3.41135e-07 (rank : 229)	NC score	0.664084 (rank : 51)
Query Neighborhood Hits	608	Target Neighborhood Hits	226	Shared Neighborhood Hits	207
SwissProt Accessions	Q8TCA0, Q5T6D4, Q5T6D6, Q9NVA6, Q9NVG3	Gene names	LRRC20
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 20.

SLIK2_HUMAN
θ value	3.41135e-07 (rank : 230)	NC score	0.498064 (rank : 208)
Query Neighborhood Hits	608	Target Neighborhood Hits	285	Shared Neighborhood Hits	235
SwissProt Accessions	Q9H156, Q5JXB1, Q8NBC7, Q96JH3	Gene names	SLITRK2, CXorf2, KIAA1854, SLITL1
Domain Architecture
Description	SLIT and NTRK-like protein 2 precursor.

NEB1_HUMAN
θ value	4.45536e-07 (rank : 231)	NC score	0.283940 (rank : 357)
Query Neighborhood Hits	608	Target Neighborhood Hits	829	Shared Neighborhood Hits	159
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SLIK1_HUMAN
θ value	4.45536e-07 (rank : 232)	NC score	0.519153 (rank : 171)
Query Neighborhood Hits	608	Target Neighborhood Hits	297	Shared Neighborhood Hits	238
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

SLIK1_MOUSE
θ value	4.45536e-07 (rank : 233)	NC score	0.518357 (rank : 173)
Query Neighborhood Hits	608	Target Neighborhood Hits	333	Shared Neighborhood Hits	242
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

SLIT1_MOUSE
θ value	4.45536e-07 (rank : 234)	NC score	0.399654 (rank : 294)
Query Neighborhood Hits	608	Target Neighborhood Hits	715	Shared Neighborhood Hits	240
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ARHGC_HUMAN
θ value	5.81887e-07 (rank : 235)	NC score	0.230238 (rank : 388)
Query Neighborhood Hits	608	Target Neighborhood Hits	351	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LRFN5_HUMAN
θ value	5.81887e-07 (rank : 236)	NC score	0.524575 (rank : 155)
Query Neighborhood Hits	608	Target Neighborhood Hits	464	Shared Neighborhood Hits	236
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_MOUSE
θ value	5.81887e-07 (rank : 237)	NC score	0.522599 (rank : 161)
Query Neighborhood Hits	608	Target Neighborhood Hits	472	Shared Neighborhood Hits	236
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

SNTG2_HUMAN
θ value	5.81887e-07 (rank : 238)	NC score	0.413945 (rank : 283)
Query Neighborhood Hits	608	Target Neighborhood Hits	191	Shared Neighborhood Hits	181
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

GP1BA_HUMAN
θ value	7.59969e-07 (rank : 239)	NC score	0.629731 (rank : 77)
Query Neighborhood Hits	608	Target Neighborhood Hits	407	Shared Neighborhood Hits	243
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

LRRN1_HUMAN
θ value	7.59969e-07 (rank : 240)	NC score	0.536567 (rank : 143)
Query Neighborhood Hits	608	Target Neighborhood Hits	518	Shared Neighborhood Hits	233
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

TLR11_MOUSE
θ value	7.59969e-07 (rank : 241)	NC score	0.642402 (rank : 67)
Query Neighborhood Hits	608	Target Neighborhood Hits	293	Shared Neighborhood Hits	238
SwissProt Accessions	Q6R5P0	Gene names	Tlr11
Domain Architecture	No domain graphic available
Description	Toll-like receptor 11 precursor.

ZO2_MOUSE
θ value	7.59969e-07 (rank : 242)	NC score	0.399305 (rank : 295)
Query Neighborhood Hits	608	Target Neighborhood Hits	296	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

K1849_HUMAN
θ value	9.92553e-07 (rank : 243)	NC score	0.350726 (rank : 311)
Query Neighborhood Hits	608	Target Neighborhood Hits	220	Shared Neighborhood Hits	153
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

OMGP_HUMAN
θ value	9.92553e-07 (rank : 244)	NC score	0.644711 (rank : 65)
Query Neighborhood Hits	608	Target Neighborhood Hits	268	Shared Neighborhood Hits	233
SwissProt Accessions	P23515	Gene names	OMG, OMGP
Domain Architecture
Description	Oligodendrocyte-myelin glycoprotein precursor.

TLR7_HUMAN
θ value	9.92553e-07 (rank : 245)	NC score	0.565027 (rank : 119)
Query Neighborhood Hits	608	Target Neighborhood Hits	312	Shared Neighborhood Hits	238
SwissProt Accessions	Q9NYK1, Q9NR98	Gene names	TLR7
Domain Architecture
Description	Toll-like receptor 7 precursor.

TLR7_MOUSE
θ value	9.92553e-07 (rank : 246)	NC score	0.563316 (rank : 120)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	239
SwissProt Accessions	P58681, Q923I1	Gene names	Tlr7
Domain Architecture
Description	Toll-like receptor 7 precursor.

ARHGC_MOUSE
θ value	1.29631e-06 (rank : 247)	NC score	0.226011 (rank : 393)
Query Neighborhood Hits	608	Target Neighborhood Hits	344	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LRRC4_HUMAN
θ value	1.69304e-06 (rank : 248)	NC score	0.521999 (rank : 163)
Query Neighborhood Hits	608	Target Neighborhood Hits	444	Shared Neighborhood Hits	225
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

LRRC4_MOUSE
θ value	1.69304e-06 (rank : 249)	NC score	0.526766 (rank : 152)
Query Neighborhood Hits	608	Target Neighborhood Hits	412	Shared Neighborhood Hits	225
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

SNTA1_MOUSE
θ value	1.69304e-06 (rank : 250)	NC score	0.384061 (rank : 302)
Query Neighborhood Hits	608	Target Neighborhood Hits	170	Shared Neighborhood Hits	164
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

LRRN3_HUMAN
θ value	2.21117e-06 (rank : 251)	NC score	0.515576 (rank : 175)
Query Neighborhood Hits	608	Target Neighborhood Hits	461	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

OMGP_MOUSE
θ value	2.21117e-06 (rank : 252)	NC score	0.639954 (rank : 69)
Query Neighborhood Hits	608	Target Neighborhood Hits	280	Shared Neighborhood Hits	233
SwissProt Accessions	Q63912	Gene names	Omg, Omgp
Domain Architecture
Description	Oligodendrocyte-myelin glycoprotein precursor.

SLIK5_MOUSE
θ value	2.21117e-06 (rank : 253)	NC score	0.498040 (rank : 209)
Query Neighborhood Hits	608	Target Neighborhood Hits	301	Shared Neighborhood Hits	237
SwissProt Accessions	Q810B7, Q9CT21	Gene names	Slitrk5
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor.

PAR6G_HUMAN
θ value	2.88788e-06 (rank : 254)	NC score	0.296193 (rank : 341)
Query Neighborhood Hits	608	Target Neighborhood Hits	159	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

SLIK4_MOUSE
θ value	2.88788e-06 (rank : 255)	NC score	0.522375 (rank : 162)
Query Neighborhood Hits	608	Target Neighborhood Hits	292	Shared Neighborhood Hits	238
SwissProt Accessions	Q810B8, Q8BL56, Q8BWB0, Q8BYG4, Q8C056	Gene names	Slitrk4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

SLIK5_HUMAN
θ value	2.88788e-06 (rank : 256)	NC score	0.497813 (rank : 210)
Query Neighborhood Hits	608	Target Neighborhood Hits	302	Shared Neighborhood Hits	236
SwissProt Accessions	O94991	Gene names	SLITRK5, KIAA0918, LRRC11
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor (Leucine-rich repeat-containing protein 11).

SNTG2_MOUSE
θ value	2.88788e-06 (rank : 257)	NC score	0.393184 (rank : 296)
Query Neighborhood Hits	608	Target Neighborhood Hits	176	Shared Neighborhood Hits	169
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

IL16_MOUSE
θ value	3.77169e-06 (rank : 258)	NC score	0.434869 (rank : 266)
Query Neighborhood Hits	608	Target Neighborhood Hits	189	Shared Neighborhood Hits	145
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LRC21_MOUSE
θ value	4.92598e-06 (rank : 259)	NC score	0.506264 (rank : 191)
Query Neighborhood Hits	608	Target Neighborhood Hits	462	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

R4RL1_HUMAN
θ value	4.92598e-06 (rank : 260)	NC score	0.521196 (rank : 167)
Query Neighborhood Hits	608	Target Neighborhood Hits	240	Shared Neighborhood Hits	211
SwissProt Accessions	Q86UN2, Q8ND46	Gene names	RTN4RL1, NGRH2, NGRL2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

TLR9_HUMAN
θ value	4.92598e-06 (rank : 261)	NC score	0.543617 (rank : 142)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	231
SwissProt Accessions	Q9NR96, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2, Q9NYC3	Gene names	TLR9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LRC55_MOUSE
θ value	6.43352e-06 (rank : 262)	NC score	0.530537 (rank : 147)
Query Neighborhood Hits	608	Target Neighborhood Hits	254	Shared Neighborhood Hits	223
SwissProt Accessions	Q3UY51	Gene names	Lrrc55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LRC27_HUMAN
θ value	8.40245e-06 (rank : 263)	NC score	0.510045 (rank : 185)
Query Neighborhood Hits	608	Target Neighborhood Hits	710	Shared Neighborhood Hits	237
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

SHAN1_HUMAN
θ value	1.09739e-05 (rank : 264)	NC score	0.139042 (rank : 438)
Query Neighborhood Hits	608	Target Neighborhood Hits	1041	Shared Neighborhood Hits	198
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SLIK4_HUMAN
θ value	1.09739e-05 (rank : 265)	NC score	0.521374 (rank : 166)
Query Neighborhood Hits	608	Target Neighborhood Hits	287	Shared Neighborhood Hits	236
SwissProt Accessions	Q8IW52, Q8TCM8, Q96DL3	Gene names	SLITRK4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

APBA3_HUMAN
θ value	1.43324e-05 (rank : 266)	NC score	0.282188 (rank : 363)
Query Neighborhood Hits	608	Target Neighborhood Hits	201	Shared Neighborhood Hits	155
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHGB_HUMAN
θ value	1.43324e-05 (rank : 267)	NC score	0.233156 (rank : 386)
Query Neighborhood Hits	608	Target Neighborhood Hits	375	Shared Neighborhood Hits	175
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

LRC21_HUMAN
θ value	1.43324e-05 (rank : 268)	NC score	0.491640 (rank : 215)
Query Neighborhood Hits	608	Target Neighborhood Hits	456	Shared Neighborhood Hits	221
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

PAR6B_MOUSE
θ value	1.43324e-05 (rank : 269)	NC score	0.295590 (rank : 344)
Query Neighborhood Hits	608	Target Neighborhood Hits	128	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PCLO_MOUSE
θ value	1.87187e-05 (rank : 270)	NC score	0.130112 (rank : 445)
Query Neighborhood Hits	608	Target Neighborhood Hits	2275	Shared Neighborhood Hits	233
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

LRRN3_MOUSE
θ value	2.44474e-05 (rank : 271)	NC score	0.528171 (rank : 150)
Query Neighborhood Hits	608	Target Neighborhood Hits	455	Shared Neighborhood Hits	226
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

TLR12_MOUSE
θ value	2.44474e-05 (rank : 272)	NC score	0.523590 (rank : 159)
Query Neighborhood Hits	608	Target Neighborhood Hits	268	Shared Neighborhood Hits	217
SwissProt Accessions	Q6QNU9	Gene names	Tlr12
Domain Architecture	No domain graphic available
Description	Toll-like receptor 12 precursor.

TLR1_MOUSE
θ value	2.44474e-05 (rank : 273)	NC score	0.466329 (rank : 242)
Query Neighborhood Hits	608	Target Neighborhood Hits	286	Shared Neighborhood Hits	235
SwissProt Accessions	Q9EPQ1, Q9EPW5	Gene names	Tlr1
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

TLR4_HUMAN
θ value	2.44474e-05 (rank : 274)	NC score	0.515351 (rank : 177)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	234
SwissProt Accessions	O00206, Q9UK78, Q9UM57	Gene names	TLR4
Domain Architecture
Description	Toll-like receptor 4 precursor (hToll) (CD284 antigen).

PAR6B_HUMAN
θ value	3.19293e-05 (rank : 275)	NC score	0.294189 (rank : 349)
Query Neighborhood Hits	608	Target Neighborhood Hits	126	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PDLI2_MOUSE
θ value	3.19293e-05 (rank : 276)	NC score	0.275548 (rank : 367)
Query Neighborhood Hits	608	Target Neighborhood Hits	220	Shared Neighborhood Hits	127
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

SLIK6_HUMAN
θ value	3.19293e-05 (rank : 277)	NC score	0.523608 (rank : 158)
Query Neighborhood Hits	608	Target Neighborhood Hits	297	Shared Neighborhood Hits	237
SwissProt Accessions	Q9H5Y7, Q495Q0, Q6AW93, Q9HAA8, Q9NT60	Gene names	SLITRK6
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 6 precursor.

ZO3_HUMAN
θ value	3.19293e-05 (rank : 278)	NC score	0.417228 (rank : 281)
Query Neighborhood Hits	608	Target Neighborhood Hits	219	Shared Neighborhood Hits	180
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

KERA_HUMAN
θ value	4.1701e-05 (rank : 279)	NC score	0.581546 (rank : 113)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	232
SwissProt Accessions	O60938	Gene names	KERA
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

PAR6A_HUMAN
θ value	4.1701e-05 (rank : 280)	NC score	0.281656 (rank : 364)
Query Neighborhood Hits	608	Target Neighborhood Hits	119	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	4.1701e-05 (rank : 281)	NC score	0.282383 (rank : 361)
Query Neighborhood Hits	608	Target Neighborhood Hits	115	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6G_MOUSE
θ value	4.1701e-05 (rank : 282)	NC score	0.291665 (rank : 354)
Query Neighborhood Hits	608	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

SLIK6_MOUSE
θ value	4.1701e-05 (rank : 283)	NC score	0.520478 (rank : 168)
Query Neighborhood Hits	608	Target Neighborhood Hits	302	Shared Neighborhood Hits	237
SwissProt Accessions	Q8C110, Q8BLL0	Gene names	Slitrk6, Sltk6
Domain Architecture
Description	SLIT and NTRK-like protein 6 precursor.

DVL2_MOUSE
θ value	5.44631e-05 (rank : 284)	NC score	0.283789 (rank : 358)
Query Neighborhood Hits	608	Target Neighborhood Hits	233	Shared Neighborhood Hits	123
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

TLR8_MOUSE
θ value	5.44631e-05 (rank : 285)	NC score	0.531982 (rank : 146)
Query Neighborhood Hits	608	Target Neighborhood Hits	297	Shared Neighborhood Hits	234
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

R4RL1_MOUSE
θ value	9.29e-05 (rank : 286)	NC score	0.500593 (rank : 204)
Query Neighborhood Hits	608	Target Neighborhood Hits	235	Shared Neighborhood Hits	199
SwissProt Accessions	Q8K0S5	Gene names	Rtn4rl1, Ngrl2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

APBA2_HUMAN
θ value	0.000121331 (rank : 287)	NC score	0.286713 (rank : 355)
Query Neighborhood Hits	608	Target Neighborhood Hits	220	Shared Neighborhood Hits	158
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.000121331 (rank : 288)	NC score	0.286511 (rank : 356)
Query Neighborhood Hits	608	Target Neighborhood Hits	219	Shared Neighborhood Hits	157
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

OPT_MOUSE
θ value	0.000121331 (rank : 289)	NC score	0.510214 (rank : 184)
Query Neighborhood Hits	608	Target Neighborhood Hits	240	Shared Neighborhood Hits	217
SwissProt Accessions	Q920A0, Q91ZZ9	Gene names	Optc, Opt
Domain Architecture
Description	Opticin precursor (Oculoglycan).

AMGO2_HUMAN
θ value	0.000158464 (rank : 290)	NC score	0.529136 (rank : 149)
Query Neighborhood Hits	608	Target Neighborhood Hits	357	Shared Neighborhood Hits	224
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

SDCB1_MOUSE
θ value	0.000158464 (rank : 291)	NC score	0.301746 (rank : 335)
Query Neighborhood Hits	608	Target Neighborhood Hits	144	Shared Neighborhood Hits	135
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

AFAD_HUMAN
θ value	0.00020696 (rank : 292)	NC score	0.302973 (rank : 334)
Query Neighborhood Hits	608	Target Neighborhood Hits	689	Shared Neighborhood Hits	168
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

DVL3_HUMAN
θ value	0.00020696 (rank : 293)	NC score	0.294970 (rank : 348)
Query Neighborhood Hits	608	Target Neighborhood Hits	194	Shared Neighborhood Hits	118
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	0.00020696 (rank : 294)	NC score	0.295189 (rank : 347)
Query Neighborhood Hits	608	Target Neighborhood Hits	198	Shared Neighborhood Hits	121
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

K1849_MOUSE
θ value	0.00020696 (rank : 295)	NC score	0.332213 (rank : 319)
Query Neighborhood Hits	608	Target Neighborhood Hits	335	Shared Neighborhood Hits	158
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

RPGF6_HUMAN
θ value	0.00020696 (rank : 296)	NC score	0.261461 (rank : 375)
Query Neighborhood Hits	608	Target Neighborhood Hits	266	Shared Neighborhood Hits	163
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

CT075_MOUSE
θ value	0.000270298 (rank : 297)	NC score	0.546802 (rank : 136)
Query Neighborhood Hits	608	Target Neighborhood Hits	358	Shared Neighborhood Hits	234
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

DVL1_HUMAN
θ value	0.000270298 (rank : 298)	NC score	0.295543 (rank : 345)
Query Neighborhood Hits	608	Target Neighborhood Hits	158	Shared Neighborhood Hits	123
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

GRASP_HUMAN
θ value	0.000270298 (rank : 299)	NC score	0.296956 (rank : 340)
Query Neighborhood Hits	608	Target Neighborhood Hits	147	Shared Neighborhood Hits	129
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	0.000270298 (rank : 300)	NC score	0.293908 (rank : 350)
Query Neighborhood Hits	608	Target Neighborhood Hits	131	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

SDCB1_HUMAN
θ value	0.000270298 (rank : 301)	NC score	0.299897 (rank : 337)
Query Neighborhood Hits	608	Target Neighborhood Hits	150	Shared Neighborhood Hits	143
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB2_MOUSE
θ value	0.000270298 (rank : 302)	NC score	0.257099 (rank : 376)
Query Neighborhood Hits	608	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SLIK3_HUMAN
θ value	0.000270298 (rank : 303)	NC score	0.490910 (rank : 216)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	235
SwissProt Accessions	O94933	Gene names	SLITRK3, KIAA0848
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 3 precursor.

PDLI1_MOUSE
θ value	0.00035302 (rank : 304)	NC score	0.190302 (rank : 409)
Query Neighborhood Hits	608	Target Neighborhood Hits	213	Shared Neighborhood Hits	105
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

TLR6_MOUSE
θ value	0.00035302 (rank : 305)	NC score	0.447786 (rank : 258)
Query Neighborhood Hits	608	Target Neighborhood Hits	288	Shared Neighborhood Hits	233
SwissProt Accessions	Q9EPW9, Q9WTQ4	Gene names	Tlr6
Domain Architecture
Description	Toll-like receptor 6 precursor.

APBA1_HUMAN
θ value	0.000461057 (rank : 306)	NC score	0.293546 (rank : 352)
Query Neighborhood Hits	608	Target Neighborhood Hits	325	Shared Neighborhood Hits	168
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

DVL1_MOUSE
θ value	0.000461057 (rank : 307)	NC score	0.292201 (rank : 353)
Query Neighborhood Hits	608	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL2_HUMAN
θ value	0.000461057 (rank : 308)	NC score	0.282809 (rank : 360)
Query Neighborhood Hits	608	Target Neighborhood Hits	223	Shared Neighborhood Hits	124
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

KERA_MOUSE
θ value	0.000461057 (rank : 309)	NC score	0.571845 (rank : 118)
Query Neighborhood Hits	608	Target Neighborhood Hits	264	Shared Neighborhood Hits	226
SwissProt Accessions	O35367	Gene names	Kera, Ktcn
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

PSCBP_MOUSE
θ value	0.000461057 (rank : 310)	NC score	0.270689 (rank : 368)
Query Neighborhood Hits	608	Target Neighborhood Hits	118	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

MPP4_MOUSE
θ value	0.000602161 (rank : 311)	NC score	0.293824 (rank : 351)
Query Neighborhood Hits	608	Target Neighborhood Hits	188	Shared Neighborhood Hits	123
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

NOS1_HUMAN
θ value	0.000602161 (rank : 312)	NC score	0.207334 (rank : 403)
Query Neighborhood Hits	608	Target Neighborhood Hits	218	Shared Neighborhood Hits	145
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SLIK3_MOUSE
θ value	0.000602161 (rank : 313)	NC score	0.489808 (rank : 217)
Query Neighborhood Hits	608	Target Neighborhood Hits	308	Shared Neighborhood Hits	236
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

STXB4_MOUSE
θ value	0.000602161 (rank : 314)	NC score	0.247326 (rank : 383)
Query Neighborhood Hits	608	Target Neighborhood Hits	629	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYP2L_HUMAN
θ value	0.000602161 (rank : 315)	NC score	0.246738 (rank : 384)
Query Neighborhood Hits	608	Target Neighborhood Hits	400	Shared Neighborhood Hits	146
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CD180_MOUSE
θ value	0.000786445 (rank : 316)	NC score	0.525303 (rank : 154)
Query Neighborhood Hits	608	Target Neighborhood Hits	283	Shared Neighborhood Hits	230
SwissProt Accessions	Q62192	Gene names	Cd180, Ly78, Rp105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 78) (Radioprotective 105 kDa protein).

LIMK2_MOUSE
θ value	0.000786445 (rank : 317)	NC score	0.021969 (rank : 529)
Query Neighborhood Hits	608	Target Neighborhood Hits	998	Shared Neighborhood Hits	81
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

MPP3_HUMAN
θ value	0.000786445 (rank : 318)	NC score	0.297027 (rank : 339)
Query Neighborhood Hits	608	Target Neighborhood Hits	171	Shared Neighborhood Hits	134
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	0.000786445 (rank : 319)	NC score	0.298935 (rank : 338)
Query Neighborhood Hits	608	Target Neighborhood Hits	165	Shared Neighborhood Hits	134
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP5_HUMAN
θ value	0.000786445 (rank : 320)	NC score	0.305148 (rank : 332)
Query Neighborhood Hits	608	Target Neighborhood Hits	231	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.000786445 (rank : 321)	NC score	0.305219 (rank : 331)
Query Neighborhood Hits	608	Target Neighborhood Hits	226	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PDLI1_HUMAN
θ value	0.000786445 (rank : 322)	NC score	0.182622 (rank : 414)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	103
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

RGS12_HUMAN
θ value	0.000786445 (rank : 323)	NC score	0.196366 (rank : 405)
Query Neighborhood Hits	608	Target Neighborhood Hits	333	Shared Neighborhood Hits	148
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SHAN2_MOUSE
θ value	0.000786445 (rank : 324)	NC score	0.197767 (rank : 404)
Query Neighborhood Hits	608	Target Neighborhood Hits	446	Shared Neighborhood Hits	147
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

STXB4_HUMAN
θ value	0.000786445 (rank : 325)	NC score	0.249531 (rank : 379)
Query Neighborhood Hits	608	Target Neighborhood Hits	616	Shared Neighborhood Hits	113
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

DVL1L_HUMAN
θ value	0.00134147 (rank : 326)	NC score	0.281295 (rank : 366)
Query Neighborhood Hits	608	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

EM55_HUMAN
θ value	0.00134147 (rank : 327)	NC score	0.269098 (rank : 369)
Query Neighborhood Hits	608	Target Neighborhood Hits	228	Shared Neighborhood Hits	129
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	0.00134147 (rank : 328)	NC score	0.267846 (rank : 370)
Query Neighborhood Hits	608	Target Neighborhood Hits	221	Shared Neighborhood Hits	126
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

LIMK2_HUMAN
θ value	0.00134147 (rank : 329)	NC score	0.020340 (rank : 533)
Query Neighborhood Hits	608	Target Neighborhood Hits	986	Shared Neighborhood Hits	84
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

PDLI5_HUMAN
θ value	0.00134147 (rank : 330)	NC score	0.146756 (rank : 430)
Query Neighborhood Hits	608	Target Neighborhood Hits	322	Shared Neighborhood Hits	123
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SYNP2_MOUSE
θ value	0.00134147 (rank : 331)	NC score	0.214387 (rank : 402)
Query Neighborhood Hits	608	Target Neighborhood Hits	252	Shared Neighborhood Hits	138
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

CT075_HUMAN
θ value	0.00175202 (rank : 332)	NC score	0.480051 (rank : 227)
Query Neighborhood Hits	608	Target Neighborhood Hits	387	Shared Neighborhood Hits	228
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

PDLI7_MOUSE
θ value	0.00175202 (rank : 333)	NC score	0.135381 (rank : 440)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	107
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

TLR3_HUMAN
θ value	0.00175202 (rank : 334)	NC score	0.573357 (rank : 117)
Query Neighborhood Hits	608	Target Neighborhood Hits	323	Shared Neighborhood Hits	242
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

LRC17_MOUSE
θ value	0.00228821 (rank : 335)	NC score	0.504085 (rank : 196)
Query Neighborhood Hits	608	Target Neighborhood Hits	268	Shared Neighborhood Hits	218
SwissProt Accessions	Q9CXD9	Gene names	Lrrc17
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor.

RHPN1_HUMAN
θ value	0.00228821 (rank : 336)	NC score	0.223276 (rank : 398)
Query Neighborhood Hits	608	Target Neighborhood Hits	158	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RU2A_HUMAN
θ value	0.00228821 (rank : 337)	NC score	0.189750 (rank : 410)
Query Neighborhood Hits	608	Target Neighborhood Hits	130	Shared Neighborhood Hits	98
SwissProt Accessions	P09661, Q8TBD2	Gene names	SNRPA1
Domain Architecture	No domain graphic available
Description	U2 small nuclear ribonucleoprotein A' (U2 snRNP-A').

RU2A_MOUSE
θ value	0.00228821 (rank : 338)	NC score	0.188603 (rank : 411)
Query Neighborhood Hits	608	Target Neighborhood Hits	131	Shared Neighborhood Hits	98
SwissProt Accessions	P57784, Q3U7R8, Q8K2W4, Q91YW1, Q9JKQ3	Gene names	Snrpa1
Domain Architecture	No domain graphic available
Description	U2 small nuclear ribonucleoprotein A' (U2 snRNP-A').

TLR2_HUMAN
θ value	0.00228821 (rank : 339)	NC score	0.455593 (rank : 250)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	229
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

APBA3_MOUSE
θ value	0.00298849 (rank : 340)	NC score	0.263346 (rank : 374)
Query Neighborhood Hits	608	Target Neighborhood Hits	174	Shared Neighborhood Hits	144
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

LDB3_HUMAN
θ value	0.00298849 (rank : 341)	NC score	0.144421 (rank : 432)
Query Neighborhood Hits	608	Target Neighborhood Hits	497	Shared Neighborhood Hits	141
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	0.00298849 (rank : 342)	NC score	0.145757 (rank : 431)
Query Neighborhood Hits	608	Target Neighborhood Hits	510	Shared Neighborhood Hits	147
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LRC49_MOUSE
θ value	0.00298849 (rank : 343)	NC score	0.449531 (rank : 255)
Query Neighborhood Hits	608	Target Neighborhood Hits	230	Shared Neighborhood Hits	187
SwissProt Accessions	Q91YK0, Q8C3S4, Q8C7T7	Gene names	Lrrc49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79).

PDLI2_HUMAN
θ value	0.00298849 (rank : 344)	NC score	0.283756 (rank : 359)
Query Neighborhood Hits	608	Target Neighborhood Hits	245	Shared Neighborhood Hits	134
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDZK4_MOUSE
θ value	0.00298849 (rank : 345)	NC score	0.309356 (rank : 327)
Query Neighborhood Hits	608	Target Neighborhood Hits	165	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PSCBP_HUMAN
θ value	0.00298849 (rank : 346)	NC score	0.247848 (rank : 382)
Query Neighborhood Hits	608	Target Neighborhood Hits	123	Shared Neighborhood Hits	117
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

SHAN2_HUMAN
θ value	0.00298849 (rank : 347)	NC score	0.216774 (rank : 401)
Query Neighborhood Hits	608	Target Neighborhood Hits	346	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SYNP2_HUMAN
θ value	0.00298849 (rank : 348)	NC score	0.176622 (rank : 420)
Query Neighborhood Hits	608	Target Neighborhood Hits	323	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

NOS1_MOUSE
θ value	0.00390308 (rank : 349)	NC score	0.180833 (rank : 415)
Query Neighborhood Hits	608	Target Neighborhood Hits	155	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PDLI7_HUMAN
θ value	0.00390308 (rank : 350)	NC score	0.141109 (rank : 437)
Query Neighborhood Hits	608	Target Neighborhood Hits	547	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDZK4_HUMAN
θ value	0.00390308 (rank : 351)	NC score	0.308081 (rank : 328)
Query Neighborhood Hits	608	Target Neighborhood Hits	165	Shared Neighborhood Hits	126
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SDCB2_HUMAN
θ value	0.00390308 (rank : 352)	NC score	0.251687 (rank : 378)
Query Neighborhood Hits	608	Target Neighborhood Hits	121	Shared Neighborhood Hits	118
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

TLR10_HUMAN
θ value	0.00390308 (rank : 353)	NC score	0.448812 (rank : 256)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	235
SwissProt Accessions	Q9BXR5, Q5FWG4, Q6UXL3	Gene names	TLR10
Domain Architecture
Description	Toll-like receptor 10 precursor.

TLR3_MOUSE
θ value	0.00390308 (rank : 354)	NC score	0.547327 (rank : 133)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	234
SwissProt Accessions	Q99MB1, Q91ZM4	Gene names	Tlr3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

TLR8_HUMAN
θ value	0.00390308 (rank : 355)	NC score	0.529628 (rank : 148)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	235
SwissProt Accessions	Q9NR97, Q6UXL6, Q9NYG9	Gene names	TLR8
Domain Architecture
Description	Toll-like receptor 8 precursor.

ZNF8_HUMAN
θ value	0.00390308 (rank : 356)	NC score	-0.012473 (rank : 672)
Query Neighborhood Hits	608	Target Neighborhood Hits	748	Shared Neighborhood Hits	11
SwissProt Accessions	P17098, Q6PI99	Gene names	ZNF8
Domain Architecture	No domain graphic available
Description	Zinc finger protein 8 (Zinc finger protein HF.18).

CAR12_HUMAN
θ value	0.00509761 (rank : 357)	NC score	0.149146 (rank : 428)
Query Neighborhood Hits	608	Target Neighborhood Hits	132	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

RIMS1_HUMAN
θ value	0.00509761 (rank : 358)	NC score	0.162430 (rank : 424)
Query Neighborhood Hits	608	Target Neighborhood Hits	437	Shared Neighborhood Hits	140
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

LRC19_MOUSE
θ value	0.00665767 (rank : 359)	NC score	0.451528 (rank : 252)
Query Neighborhood Hits	608	Target Neighborhood Hits	238	Shared Neighborhood Hits	203
SwissProt Accessions	Q8BZT5, Q6P8J1	Gene names	Lrrc19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

MAST2_HUMAN
θ value	0.00665767 (rank : 360)	NC score	0.039060 (rank : 509)
Query Neighborhood Hits	608	Target Neighborhood Hits	1189	Shared Neighborhood Hits	151
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SYP2L_MOUSE
θ value	0.00665767 (rank : 361)	NC score	0.185684 (rank : 412)
Query Neighborhood Hits	608	Target Neighborhood Hits	289	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CSKP_HUMAN
θ value	0.00869519 (rank : 362)	NC score	0.085641 (rank : 466)
Query Neighborhood Hits	608	Target Neighborhood Hits	1022	Shared Neighborhood Hits	134
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
θ value	0.00869519 (rank : 363)	NC score	0.083335 (rank : 468)
Query Neighborhood Hits	608	Target Neighborhood Hits	1027	Shared Neighborhood Hits	134
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

INVS_MOUSE
θ value	0.00869519 (rank : 364)	NC score	0.005856 (rank : 616)
Query Neighborhood Hits	608	Target Neighborhood Hits	609	Shared Neighborhood Hits	40
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MAST2_MOUSE
θ value	0.00869519 (rank : 365)	NC score	0.037920 (rank : 512)
Query Neighborhood Hits	608	Target Neighborhood Hits	1110	Shared Neighborhood Hits	143
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

OPT_HUMAN
θ value	0.00869519 (rank : 366)	NC score	0.495739 (rank : 211)
Query Neighborhood Hits	608	Target Neighborhood Hits	255	Shared Neighborhood Hits	217
SwissProt Accessions	Q9UBM4	Gene names	OPTC, OPT
Domain Architecture	No domain graphic available
Description	Opticin precursor (Oculoglycan).

PGLB_HUMAN
θ value	0.00869519 (rank : 367)	NC score	0.483741 (rank : 225)
Query Neighborhood Hits	608	Target Neighborhood Hits	250	Shared Neighborhood Hits	218
SwissProt Accessions	Q99645, Q8NEJ5	Gene names	DSPG3, PGLB
Domain Architecture
Description	Dermatan sulfate proteoglycan 3 precursor (Epiphycan) (Small chondroitin/dermatan sulfate proteoglycan) (Proteoglycan-Lb) (PG-Lb).

LRC48_MOUSE
θ value	0.0113563 (rank : 368)	NC score	0.333901 (rank : 318)
Query Neighborhood Hits	608	Target Neighborhood Hits	252	Shared Neighborhood Hits	152
SwissProt Accessions	Q9D5E4	Gene names	Lrrc48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

MAST3_HUMAN
θ value	0.0113563 (rank : 369)	NC score	0.038004 (rank : 511)
Query Neighborhood Hits	608	Target Neighborhood Hits	1128	Shared Neighborhood Hits	152
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

OGFR_HUMAN
θ value	0.0113563 (rank : 370)	NC score	0.026256 (rank : 522)
Query Neighborhood Hits	608	Target Neighborhood Hits	1582	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CD180_HUMAN
θ value	0.0148317 (rank : 371)	NC score	0.521475 (rank : 165)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	228
SwissProt Accessions	Q99467	Gene names	CD180, LY64, RP105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 64) (Radioprotective 105 kDa protein).

LRC49_HUMAN
θ value	0.0148317 (rank : 372)	NC score	0.405336 (rank : 289)
Query Neighborhood Hits	608	Target Neighborhood Hits	210	Shared Neighborhood Hits	164
SwissProt Accessions	Q8IUZ0, Q9NXM6	Gene names	LRRC49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4).

RPGF2_HUMAN
θ value	0.0148317 (rank : 373)	NC score	0.220317 (rank : 399)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

MAST4_HUMAN
θ value	0.0193708 (rank : 374)	NC score	0.041135 (rank : 505)
Query Neighborhood Hits	608	Target Neighborhood Hits	1804	Shared Neighborhood Hits	186
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

TIAM1_MOUSE
θ value	0.0193708 (rank : 375)	NC score	0.051346 (rank : 497)
Query Neighborhood Hits	608	Target Neighborhood Hits	205	Shared Neighborhood Hits	53
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

AMGO2_MOUSE
θ value	0.0252991 (rank : 376)	NC score	0.533961 (rank : 144)
Query Neighborhood Hits	608	Target Neighborhood Hits	329	Shared Neighborhood Hits	230
SwissProt Accessions	Q80ZD9	Gene names	Amigo2, Ali1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1).

GLI3_HUMAN
θ value	0.0252991 (rank : 377)	NC score	-0.009791 (rank : 670)
Query Neighborhood Hits	608	Target Neighborhood Hits	871	Shared Neighborhood Hits	25
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

MAST1_MOUSE
θ value	0.0252991 (rank : 378)	NC score	0.038423 (rank : 510)
Query Neighborhood Hits	608	Target Neighborhood Hits	1123	Shared Neighborhood Hits	149
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PTN4_HUMAN
θ value	0.0252991 (rank : 379)	NC score	0.105490 (rank : 457)
Query Neighborhood Hits	608	Target Neighborhood Hits	303	Shared Neighborhood Hits	124
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

SRCA_MOUSE
θ value	0.0252991 (rank : 380)	NC score	0.020060 (rank : 534)
Query Neighborhood Hits	608	Target Neighborhood Hits	212	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TLR1_HUMAN
θ value	0.0252991 (rank : 381)	NC score	0.429485 (rank : 271)
Query Neighborhood Hits	608	Target Neighborhood Hits	280	Shared Neighborhood Hits	223
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

BTBD7_HUMAN
θ value	0.0330416 (rank : 382)	NC score	0.017327 (rank : 547)
Query Neighborhood Hits	608	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

LRC17_HUMAN
θ value	0.0330416 (rank : 383)	NC score	0.489277 (rank : 218)
Query Neighborhood Hits	608	Target Neighborhood Hits	267	Shared Neighborhood Hits	221
SwissProt Accessions	Q8N6Y2, Q13288, Q6UWA7, Q75MG5	Gene names	LRRC17, P37NB
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor (p37NB).

MAST1_HUMAN
θ value	0.0330416 (rank : 384)	NC score	0.037413 (rank : 514)
Query Neighborhood Hits	608	Target Neighborhood Hits	1146	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PRAX_HUMAN
θ value	0.0330416 (rank : 385)	NC score	0.093938 (rank : 465)
Query Neighborhood Hits	608	Target Neighborhood Hits	215	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

RHPN1_MOUSE
θ value	0.0330416 (rank : 386)	NC score	0.232420 (rank : 387)
Query Neighborhood Hits	608	Target Neighborhood Hits	154	Shared Neighborhood Hits	134
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RTN4R_MOUSE
θ value	0.0330416 (rank : 387)	NC score	0.503768 (rank : 199)
Query Neighborhood Hits	608	Target Neighborhood Hits	293	Shared Neighborhood Hits	229
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

SI1L2_HUMAN
θ value	0.0330416 (rank : 388)	NC score	0.051828 (rank : 495)
Query Neighborhood Hits	608	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

TLR2_MOUSE
θ value	0.0330416 (rank : 389)	NC score	0.458203 (rank : 248)
Query Neighborhood Hits	608	Target Neighborhood Hits	283	Shared Neighborhood Hits	225
SwissProt Accessions	Q9QUN7, Q3U400, Q9DBC4	Gene names	Tlr2
Domain Architecture
Description	Toll-like receptor 2 precursor (CD282 antigen).

CLC4M_HUMAN
θ value	0.0431538 (rank : 390)	NC score	0.030261 (rank : 520)
Query Neighborhood Hits	608	Target Neighborhood Hits	291	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

GPS2_HUMAN
θ value	0.0431538 (rank : 391)	NC score	0.042841 (rank : 502)
Query Neighborhood Hits	608	Target Neighborhood Hits	459	Shared Neighborhood Hits	30
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

RIMS2_HUMAN
θ value	0.0431538 (rank : 392)	NC score	0.130211 (rank : 444)
Query Neighborhood Hits	608	Target Neighborhood Hits	342	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.0431538 (rank : 393)	NC score	0.128566 (rank : 448)
Query Neighborhood Hits	608	Target Neighborhood Hits	376	Shared Neighborhood Hits	116
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

ADCY4_MOUSE
θ value	0.0563607 (rank : 394)	NC score	0.010231 (rank : 577)
Query Neighborhood Hits	608	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WF3	Gene names	Adcy4
Domain Architecture
Description	Adenylate cyclase type 4 (EC 4.6.1.1) (Adenylate cyclase type IV) (ATP pyrophosphate-lyase 4) (Adenylyl cyclase 4).

PDLI5_MOUSE
θ value	0.0563607 (rank : 395)	NC score	0.142609 (rank : 435)
Query Neighborhood Hits	608	Target Neighborhood Hits	287	Shared Neighborhood Hits	124
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

CARD4_HUMAN
θ value	0.0736092 (rank : 396)	NC score	0.049271 (rank : 499)
Query Neighborhood Hits	608	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

PGLB_MOUSE
θ value	0.0736092 (rank : 397)	NC score	0.470147 (rank : 239)
Query Neighborhood Hits	608	Target Neighborhood Hits	243	Shared Neighborhood Hits	212
SwissProt Accessions	P70186	Gene names	Dspg3, Pglb
Domain Architecture
Description	Dermatan sulfate proteoglycan 3 precursor (Epiphycan) (Small chondroitin/dermatan sulfate proteoglycan) (Proteoglycan-Lb) (PG-Lb).

PRAX_MOUSE
θ value	0.0736092 (rank : 398)	NC score	0.105848 (rank : 456)
Query Neighborhood Hits	608	Target Neighborhood Hits	199	Shared Neighborhood Hits	58
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

RP1L1_HUMAN
θ value	0.0736092 (rank : 399)	NC score	0.026664 (rank : 521)
Query Neighborhood Hits	608	Target Neighborhood Hits	1072	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

GP125_HUMAN
θ value	0.0961366 (rank : 400)	NC score	0.336026 (rank : 317)
Query Neighborhood Hits	608	Target Neighborhood Hits	327	Shared Neighborhood Hits	195
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

K0256_MOUSE
θ value	0.0961366 (rank : 401)	NC score	0.017511 (rank : 544)
Query Neighborhood Hits	608	Target Neighborhood Hits	121	Shared Neighborhood Hits	17
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

LRC48_HUMAN
θ value	0.0961366 (rank : 402)	NC score	0.350224 (rank : 313)
Query Neighborhood Hits	608	Target Neighborhood Hits	324	Shared Neighborhood Hits	157
SwissProt Accessions	Q9H069, Q86SF9, Q86W73, Q8IWG0	Gene names	LRRC48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

MEGF8_HUMAN
θ value	0.0961366 (rank : 403)	NC score	0.009790 (rank : 582)
Query Neighborhood Hits	608	Target Neighborhood Hits	528	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

PRAM7_HUMAN
θ value	0.0961366 (rank : 404)	NC score	0.014882 (rank : 557)
Query Neighborhood Hits	608	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VXH5	Gene names	PRAMEF7
Domain Architecture	No domain graphic available
Description	PRAME family member 7.

PRAM8_HUMAN
θ value	0.0961366 (rank : 405)	NC score	0.014946 (rank : 556)
Query Neighborhood Hits	608	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VWM4	Gene names	PRAMEF8
Domain Architecture	No domain graphic available
Description	PRAME family member 8.

EPHB6_MOUSE
θ value	0.125558 (rank : 406)	NC score	0.000834 (rank : 650)
Query Neighborhood Hits	608	Target Neighborhood Hits	906	Shared Neighborhood Hits	33
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

PGTA_MOUSE
θ value	0.125558 (rank : 407)	NC score	0.295795 (rank : 343)
Query Neighborhood Hits	608	Target Neighborhood Hits	150	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JHK4, Q9JLX2	Gene names	Rabggta
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

PRRT3_HUMAN
θ value	0.125558 (rank : 408)	NC score	0.022691 (rank : 526)
Query Neighborhood Hits	608	Target Neighborhood Hits	998	Shared Neighborhood Hits	78
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PSMF1_MOUSE
θ value	0.125558 (rank : 409)	NC score	0.019780 (rank : 535)
Query Neighborhood Hits	608	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

SEPT9_HUMAN
θ value	0.125558 (rank : 410)	NC score	0.010928 (rank : 574)
Query Neighborhood Hits	608	Target Neighborhood Hits	706	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TJAP1_MOUSE
θ value	0.125558 (rank : 411)	NC score	0.017419 (rank : 545)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

CP053_HUMAN
θ value	0.163984 (rank : 412)	NC score	0.024536 (rank : 523)
Query Neighborhood Hits	608	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

HTRA2_HUMAN
θ value	0.163984 (rank : 413)	NC score	0.049461 (rank : 498)
Query Neighborhood Hits	608	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA3_MOUSE
θ value	0.163984 (rank : 414)	NC score	0.083445 (rank : 467)
Query Neighborhood Hits	608	Target Neighborhood Hits	156	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

LRC52_MOUSE
θ value	0.163984 (rank : 415)	NC score	0.470365 (rank : 238)
Query Neighborhood Hits	608	Target Neighborhood Hits	240	Shared Neighborhood Hits	209
SwissProt Accessions	Q5M8M9	Gene names	Lrrc52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

LSHR_MOUSE
θ value	0.163984 (rank : 416)	NC score	0.148281 (rank : 429)
Query Neighborhood Hits	608	Target Neighborhood Hits	686	Shared Neighborhood Hits	125
SwissProt Accessions	P30730	Gene names	Lhcgr, Lhr
Domain Architecture
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH- R) (Luteinizing hormone receptor).

MIME_MOUSE
θ value	0.163984 (rank : 417)	NC score	0.474391 (rank : 234)
Query Neighborhood Hits	608	Target Neighborhood Hits	234	Shared Neighborhood Hits	208
SwissProt Accessions	Q62000	Gene names	Ogn, Og
Domain Architecture
Description	Mimecan precursor (Osteoglycin).

PGTA_HUMAN
θ value	0.163984 (rank : 418)	NC score	0.322612 (rank : 321)
Query Neighborhood Hits	608	Target Neighborhood Hits	160	Shared Neighborhood Hits	128
SwissProt Accessions	Q92696	Gene names	RABGGTA
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

RGS3_HUMAN
θ value	0.163984 (rank : 419)	NC score	0.052386 (rank : 491)
Query Neighborhood Hits	608	Target Neighborhood Hits	1375	Shared Neighborhood Hits	136
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GEMI5_MOUSE
θ value	0.21417 (rank : 420)	NC score	0.004959 (rank : 622)
Query Neighborhood Hits	608	Target Neighborhood Hits	424	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

GIPC2_HUMAN
θ value	0.21417 (rank : 421)	NC score	0.130035 (rank : 446)
Query Neighborhood Hits	608	Target Neighborhood Hits	93	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

K1688_MOUSE
θ value	0.21417 (rank : 422)	NC score	0.017316 (rank : 548)
Query Neighborhood Hits	608	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

LRP3_HUMAN
θ value	0.21417 (rank : 423)	NC score	0.008883 (rank : 591)
Query Neighborhood Hits	608	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

PDLI4_HUMAN
θ value	0.21417 (rank : 424)	NC score	0.180788 (rank : 416)
Query Neighborhood Hits	608	Target Neighborhood Hits	245	Shared Neighborhood Hits	118
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	0.21417 (rank : 425)	NC score	0.184510 (rank : 413)
Query Neighborhood Hits	608	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PTN3_HUMAN
θ value	0.21417 (rank : 426)	NC score	0.103712 (rank : 461)
Query Neighborhood Hits	608	Target Neighborhood Hits	258	Shared Neighborhood Hits	118
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

TBCD2_HUMAN
θ value	0.21417 (rank : 427)	NC score	0.009872 (rank : 580)
Query Neighborhood Hits	608	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TIAM1_HUMAN
θ value	0.21417 (rank : 428)	NC score	0.063747 (rank : 482)
Query Neighborhood Hits	608	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TM108_MOUSE
θ value	0.21417 (rank : 429)	NC score	0.023758 (rank : 524)
Query Neighborhood Hits	608	Target Neighborhood Hits	336	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

EVPL_HUMAN
θ value	0.279714 (rank : 430)	NC score	0.005614 (rank : 618)
Query Neighborhood Hits	608	Target Neighborhood Hits	895	Shared Neighborhood Hits	39
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

GIPC1_MOUSE
θ value	0.279714 (rank : 431)	NC score	0.150871 (rank : 426)
Query Neighborhood Hits	608	Target Neighborhood Hits	92	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

HTRA3_HUMAN
θ value	0.279714 (rank : 432)	NC score	0.079349 (rank : 472)
Query Neighborhood Hits	608	Target Neighborhood Hits	152	Shared Neighborhood Hits	69
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

LGI4_HUMAN
θ value	0.279714 (rank : 433)	NC score	0.383011 (rank : 303)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	209
SwissProt Accessions	Q8N135	Gene names	LGI4, LGIL3
Domain Architecture
Description	Leucine-rich repeat LGI family member 4 precursor (Leucine-rich glioma-inactivated protein 4) (LGI1-like protein 3).

LIMK1_HUMAN
θ value	0.279714 (rank : 434)	NC score	0.020754 (rank : 531)
Query Neighborhood Hits	608	Target Neighborhood Hits	1005	Shared Neighborhood Hits	92
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LRC52_HUMAN
θ value	0.279714 (rank : 435)	NC score	0.460837 (rank : 245)
Query Neighborhood Hits	608	Target Neighborhood Hits	229	Shared Neighborhood Hits	201
SwissProt Accessions	Q8N7C0, Q5T9K5	Gene names	LRRC52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

LRC61_HUMAN
θ value	0.279714 (rank : 436)	NC score	0.168417 (rank : 423)
Query Neighborhood Hits	608	Target Neighborhood Hits	85	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BV99	Gene names	LRRC61
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 61.

MPP2_HUMAN
θ value	0.279714 (rank : 437)	NC score	0.224765 (rank : 395)
Query Neighborhood Hits	608	Target Neighborhood Hits	173	Shared Neighborhood Hits	97
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	0.279714 (rank : 438)	NC score	0.226655 (rank : 391)
Query Neighborhood Hits	608	Target Neighborhood Hits	189	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

BRE1B_HUMAN
θ value	0.365318 (rank : 439)	NC score	0.007308 (rank : 603)
Query Neighborhood Hits	608	Target Neighborhood Hits	1040	Shared Neighborhood Hits	47
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

EPHB6_HUMAN
θ value	0.365318 (rank : 440)	NC score	-0.000067 (rank : 652)
Query Neighborhood Hits	608	Target Neighborhood Hits	912	Shared Neighborhood Hits	30
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

K0157_HUMAN
θ value	0.365318 (rank : 441)	NC score	0.015782 (rank : 553)
Query Neighborhood Hits	608	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q15018, Q96H11	Gene names	KIAA0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

LGI2_HUMAN
θ value	0.365318 (rank : 442)	NC score	0.380801 (rank : 304)
Query Neighborhood Hits	608	Target Neighborhood Hits	232	Shared Neighborhood Hits	200
SwissProt Accessions	Q8N0V4, Q8NDW6, Q96PX2, Q9NVK4	Gene names	LGI2, KIAA1916, LGIL2
Domain Architecture
Description	Leucine-rich repeat LGI family member 2 precursor (Leucine-rich glioma-inactivated protein 2) (LGI1-like protein 2).

LRC61_MOUSE
θ value	0.365318 (rank : 443)	NC score	0.225474 (rank : 394)
Query Neighborhood Hits	608	Target Neighborhood Hits	115	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R2R5, Q3TB45, Q3UPT0	Gene names	Lrrc61
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 61.

APXL_HUMAN
θ value	0.47712 (rank : 444)	NC score	0.192938 (rank : 407)
Query Neighborhood Hits	608	Target Neighborhood Hits	553	Shared Neighborhood Hits	129
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

GIPC1_HUMAN
θ value	0.47712 (rank : 445)	NC score	0.142199 (rank : 436)
Query Neighborhood Hits	608	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

IRX2_HUMAN
θ value	0.47712 (rank : 446)	NC score	0.005388 (rank : 620)
Query Neighborhood Hits	608	Target Neighborhood Hits	358	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

MTSS1_MOUSE
θ value	0.47712 (rank : 447)	NC score	0.019228 (rank : 537)
Query Neighborhood Hits	608	Target Neighborhood Hits	592	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MY18A_MOUSE
θ value	0.47712 (rank : 448)	NC score	0.041766 (rank : 503)
Query Neighborhood Hits	608	Target Neighborhood Hits	1989	Shared Neighborhood Hits	180
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CIC_HUMAN
θ value	0.62314 (rank : 449)	NC score	0.016242 (rank : 552)
Query Neighborhood Hits	608	Target Neighborhood Hits	992	Shared Neighborhood Hits	96
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LRRC3_MOUSE
θ value	0.62314 (rank : 450)	NC score	0.439862 (rank : 261)
Query Neighborhood Hits	608	Target Neighborhood Hits	236	Shared Neighborhood Hits	203
SwissProt Accessions	P59034	Gene names	Lrrc3
Domain Architecture
Description	Leucine-rich repeat-containing protein 3 precursor.

NAL12_HUMAN
θ value	0.62314 (rank : 451)	NC score	0.034597 (rank : 516)
Query Neighborhood Hits	608	Target Neighborhood Hits	96	Shared Neighborhood Hits	32
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NXF1_MOUSE
θ value	0.62314 (rank : 452)	NC score	0.045749 (rank : 501)
Query Neighborhood Hits	608	Target Neighborhood Hits	64	Shared Neighborhood Hits	39
SwissProt Accessions	Q99JX7, O88985	Gene names	Nxf1, Tap
Domain Architecture
Description	Nuclear RNA export factor 1 (Tip-associating protein) (Tip-associated protein) (mRNA export factor TAP).

PICK1_HUMAN
θ value	0.62314 (rank : 453)	NC score	0.248928 (rank : 381)
Query Neighborhood Hits	608	Target Neighborhood Hits	132	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	0.62314 (rank : 454)	NC score	0.249423 (rank : 380)
Query Neighborhood Hits	608	Target Neighborhood Hits	131	Shared Neighborhood Hits	122
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

RGS3_MOUSE
θ value	0.62314 (rank : 455)	NC score	0.052334 (rank : 493)
Query Neighborhood Hits	608	Target Neighborhood Hits	1621	Shared Neighborhood Hits	150
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CAC1H_HUMAN
θ value	0.813845 (rank : 456)	NC score	0.007229 (rank : 605)
Query Neighborhood Hits	608	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

HTRA1_HUMAN
θ value	0.813845 (rank : 457)	NC score	0.057420 (rank : 484)
Query Neighborhood Hits	608	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

MY18A_HUMAN
θ value	0.813845 (rank : 458)	NC score	0.037576 (rank : 513)
Query Neighborhood Hits	608	Target Neighborhood Hits	1929	Shared Neighborhood Hits	179
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NSBP1_MOUSE
θ value	0.813845 (rank : 459)	NC score	0.008932 (rank : 589)
Query Neighborhood Hits	608	Target Neighborhood Hits	681	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PDLI3_MOUSE
θ value	0.813845 (rank : 460)	NC score	0.180609 (rank : 417)
Query Neighborhood Hits	608	Target Neighborhood Hits	197	Shared Neighborhood Hits	109
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SRRM2_MOUSE
θ value	0.813845 (rank : 461)	NC score	0.035882 (rank : 515)
Query Neighborhood Hits	608	Target Neighborhood Hits	1470	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYNPO_MOUSE
θ value	0.813845 (rank : 462)	NC score	0.031306 (rank : 519)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TLR4_MOUSE
θ value	0.813845 (rank : 463)	NC score	0.471145 (rank : 237)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	223
SwissProt Accessions	Q9QUK6, Q9D691, Q9QZF5, Q9Z203	Gene names	Tlr4, Lps
Domain Architecture
Description	Toll-like receptor 4 precursor (CD284 antigen).

HTRA1_MOUSE
θ value	1.06291 (rank : 464)	NC score	0.055947 (rank : 486)
Query Neighborhood Hits	608	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

MPP6_HUMAN
θ value	1.06291 (rank : 465)	NC score	0.223554 (rank : 396)
Query Neighborhood Hits	608	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	1.06291 (rank : 466)	NC score	0.226054 (rank : 392)
Query Neighborhood Hits	608	Target Neighborhood Hits	187	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

PDLI3_HUMAN
θ value	1.06291 (rank : 467)	NC score	0.191856 (rank : 408)
Query Neighborhood Hits	608	Target Neighborhood Hits	199	Shared Neighborhood Hits	113
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SI1L2_MOUSE
θ value	1.06291 (rank : 468)	NC score	0.048026 (rank : 500)
Query Neighborhood Hits	608	Target Neighborhood Hits	124	Shared Neighborhood Hits	47
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
θ value	1.06291 (rank : 469)	NC score	0.040347 (rank : 507)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	53
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

FBLN2_MOUSE
θ value	1.38821 (rank : 470)	NC score	0.006491 (rank : 612)
Query Neighborhood Hits	608	Target Neighborhood Hits	505	Shared Neighborhood Hits	30
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

K1802_MOUSE
θ value	1.38821 (rank : 471)	NC score	0.003432 (rank : 631)
Query Neighborhood Hits	608	Target Neighborhood Hits	1596	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LIMK1_MOUSE
θ value	1.38821 (rank : 472)	NC score	0.018472 (rank : 541)
Query Neighborhood Hits	608	Target Neighborhood Hits	1008	Shared Neighborhood Hits	91
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

LRC55_HUMAN
θ value	1.38821 (rank : 473)	NC score	0.515435 (rank : 176)
Query Neighborhood Hits	608	Target Neighborhood Hits	257	Shared Neighborhood Hits	226
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

MAGE1_HUMAN
θ value	1.38821 (rank : 474)	NC score	0.012747 (rank : 566)
Query Neighborhood Hits	608	Target Neighborhood Hits	1389	Shared Neighborhood Hits	96
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RIMB1_HUMAN
θ value	1.38821 (rank : 475)	NC score	0.012738 (rank : 567)
Query Neighborhood Hits	608	Target Neighborhood Hits	1479	Shared Neighborhood Hits	89
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SMCE1_MOUSE
θ value	1.38821 (rank : 476)	NC score	0.008888 (rank : 590)
Query Neighborhood Hits	608	Target Neighborhood Hits	409	Shared Neighborhood Hits	24
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

TARA_HUMAN
θ value	1.38821 (rank : 477)	NC score	0.018674 (rank : 540)
Query Neighborhood Hits	608	Target Neighborhood Hits	1626	Shared Neighborhood Hits	110
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZN750_MOUSE
θ value	1.38821 (rank : 478)	NC score	0.021311 (rank : 530)
Query Neighborhood Hits	608	Target Neighborhood Hits	346	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

HNRPK_HUMAN
θ value	1.81305 (rank : 479)	NC score	0.009414 (rank : 585)
Query Neighborhood Hits	608	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
θ value	1.81305 (rank : 480)	NC score	0.009414 (rank : 586)
Query Neighborhood Hits	608	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

HTRA4_HUMAN
θ value	1.81305 (rank : 481)	NC score	0.051508 (rank : 496)
Query Neighborhood Hits	608	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

K1688_HUMAN
θ value	1.81305 (rank : 482)	NC score	0.016653 (rank : 551)
Query Neighborhood Hits	608	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

SEC63_MOUSE
θ value	1.81305 (rank : 483)	NC score	0.000866 (rank : 649)
Query Neighborhood Hits	608	Target Neighborhood Hits	601	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TBCE_HUMAN
θ value	1.81305 (rank : 484)	NC score	0.216789 (rank : 400)
Query Neighborhood Hits	608	Target Neighborhood Hits	141	Shared Neighborhood Hits	99
SwissProt Accessions	Q15813	Gene names	TBCE
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

TEX2_MOUSE
θ value	1.81305 (rank : 485)	NC score	0.011188 (rank : 573)
Query Neighborhood Hits	608	Target Neighborhood Hits	121	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

ZSCA5_HUMAN
θ value	1.81305 (rank : 486)	NC score	-0.014160 (rank : 673)
Query Neighborhood Hits	608	Target Neighborhood Hits	862	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

ANR25_MOUSE
θ value	2.36792 (rank : 487)	NC score	0.002510 (rank : 636)
Query Neighborhood Hits	608	Target Neighborhood Hits	398	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CAC1G_HUMAN
θ value	2.36792 (rank : 488)	NC score	0.008100 (rank : 599)
Query Neighborhood Hits	608	Target Neighborhood Hits	587	Shared Neighborhood Hits	48
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CROCC_MOUSE
θ value	2.36792 (rank : 489)	NC score	0.002148 (rank : 641)
Query Neighborhood Hits	608	Target Neighborhood Hits	1460	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CT172_HUMAN
θ value	2.36792 (rank : 490)	NC score	0.018429 (rank : 542)
Query Neighborhood Hits	608	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H410, Q5JW56, Q9H8P4	Gene names	C20orf172
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172.

DPOG1_HUMAN
θ value	2.36792 (rank : 491)	NC score	0.014451 (rank : 559)
Query Neighborhood Hits	608	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P54098, Q8NFM2, Q92515	Gene names	POLG, MDP1, POLG1, POLGA
Domain Architecture
Description	DNA polymerase subunit gamma 1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha).

FAAA_MOUSE
θ value	2.36792 (rank : 492)	NC score	0.010733 (rank : 575)
Query Neighborhood Hits	608	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P35505	Gene names	Fah
Domain Architecture
Description	Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA).

FHOD1_HUMAN
θ value	2.36792 (rank : 493)	NC score	0.009274 (rank : 587)
Query Neighborhood Hits	608	Target Neighborhood Hits	184	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

GIPC3_HUMAN
θ value	2.36792 (rank : 494)	NC score	0.081159 (rank : 470)
Query Neighborhood Hits	608	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

HTRA2_MOUSE
θ value	2.36792 (rank : 495)	NC score	0.041356 (rank : 504)
Query Neighborhood Hits	608	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HUWE1_MOUSE
θ value	2.36792 (rank : 496)	NC score	0.005716 (rank : 617)
Query Neighborhood Hits	608	Target Neighborhood Hits	406	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

JADE2_MOUSE
θ value	2.36792 (rank : 497)	NC score	0.004473 (rank : 626)
Query Neighborhood Hits	608	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LATS1_MOUSE
θ value	2.36792 (rank : 498)	NC score	-0.003350 (rank : 663)
Query Neighborhood Hits	608	Target Neighborhood Hits	1027	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

LEO1_HUMAN
θ value	2.36792 (rank : 499)	NC score	0.008175 (rank : 598)
Query Neighborhood Hits	608	Target Neighborhood Hits	958	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MLL2_HUMAN
θ value	2.36792 (rank : 500)	NC score	0.017416 (rank : 546)
Query Neighborhood Hits	608	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PNMA2_HUMAN
θ value	2.36792 (rank : 501)	NC score	0.004791 (rank : 624)
Query Neighborhood Hits	608	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UL42, O94959, O95145, Q9UL43	Gene names	PNMA2, KIAA0883, MA2
Domain Architecture
Description	Paraneoplastic antigen Ma2 (Onconeuronal antigen MA2) (Paraneoplastic neuronal antigen MM2) (40 kDa neuronal protein).

RRBP1_MOUSE
θ value	2.36792 (rank : 502)	NC score	-0.001306 (rank : 655)
Query Neighborhood Hits	608	Target Neighborhood Hits	1650	Shared Neighborhood Hits	64
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SOX30_MOUSE
θ value	2.36792 (rank : 503)	NC score	0.004753 (rank : 625)
Query Neighborhood Hits	608	Target Neighborhood Hits	374	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

TCAL5_HUMAN
θ value	2.36792 (rank : 504)	NC score	0.007754 (rank : 600)
Query Neighborhood Hits	608	Target Neighborhood Hits	806	Shared Neighborhood Hits	46
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TXLNB_HUMAN
θ value	2.36792 (rank : 505)	NC score	0.012682 (rank : 568)
Query Neighborhood Hits	608	Target Neighborhood Hits	912	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ZMYM3_HUMAN
θ value	2.36792 (rank : 506)	NC score	0.011868 (rank : 571)
Query Neighborhood Hits	608	Target Neighborhood Hits	223	Shared Neighborhood Hits	34
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

BRD8_MOUSE
θ value	3.0926 (rank : 507)	NC score	0.008646 (rank : 594)
Query Neighborhood Hits	608	Target Neighborhood Hits	422	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CJ011_MOUSE
θ value	3.0926 (rank : 508)	NC score	0.053610 (rank : 490)
Query Neighborhood Hits	608	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D9B4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf11 homolog.

DCP1A_HUMAN
θ value	3.0926 (rank : 509)	NC score	0.008882 (rank : 592)
Query Neighborhood Hits	608	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DIAP3_MOUSE
θ value	3.0926 (rank : 510)	NC score	0.003893 (rank : 629)
Query Neighborhood Hits	608	Target Neighborhood Hits	221	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

EHMT2_MOUSE
θ value	3.0926 (rank : 511)	NC score	-0.000519 (rank : 653)
Query Neighborhood Hits	608	Target Neighborhood Hits	750	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

GIPC3_MOUSE
θ value	3.0926 (rank : 512)	NC score	0.079337 (rank : 473)
Query Neighborhood Hits	608	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

GP152_MOUSE
θ value	3.0926 (rank : 513)	NC score	-0.003537 (rank : 664)
Query Neighborhood Hits	608	Target Neighborhood Hits	607	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

HGS_HUMAN
θ value	3.0926 (rank : 514)	NC score	0.001551 (rank : 646)
Query Neighborhood Hits	608	Target Neighborhood Hits	517	Shared Neighborhood Hits	33
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

LGI4_MOUSE
θ value	3.0926 (rank : 515)	NC score	0.350961 (rank : 310)
Query Neighborhood Hits	608	Target Neighborhood Hits	228	Shared Neighborhood Hits	197
SwissProt Accessions	Q8K1S1, Q8K4Y8	Gene names	Lgi4, Lgil3
Domain Architecture
Description	Leucine-rich repeat LGI family member 4 precursor (Leucine-rich glioma-inactivated protein 4) (LGI1-like protein 3).

LRC56_MOUSE
θ value	3.0926 (rank : 516)	NC score	0.134897 (rank : 441)
Query Neighborhood Hits	608	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K375, Q571F2	Gene names	Lrrc56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MTSS1_HUMAN
θ value	3.0926 (rank : 517)	NC score	0.014243 (rank : 561)
Query Neighborhood Hits	608	Target Neighborhood Hits	504	Shared Neighborhood Hits	41
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NCOR2_HUMAN
θ value	3.0926 (rank : 518)	NC score	0.020494 (rank : 532)
Query Neighborhood Hits	608	Target Neighborhood Hits	870	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PDZD6_HUMAN
θ value	3.0926 (rank : 519)	NC score	0.113338 (rank : 453)
Query Neighborhood Hits	608	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PELP1_MOUSE
θ value	3.0926 (rank : 520)	NC score	0.017289 (rank : 549)
Query Neighborhood Hits	608	Target Neighborhood Hits	709	Shared Neighborhood Hits	67
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RUSC2_MOUSE
θ value	3.0926 (rank : 521)	NC score	0.014306 (rank : 560)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	36
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SEC63_HUMAN
θ value	3.0926 (rank : 522)	NC score	0.000552 (rank : 651)
Query Neighborhood Hits	608	Target Neighborhood Hits	586	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

STAT2_MOUSE
θ value	3.0926 (rank : 523)	NC score	0.003250 (rank : 632)
Query Neighborhood Hits	608	Target Neighborhood Hits	175	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

TLE1_HUMAN
θ value	3.0926 (rank : 524)	NC score	-0.001599 (rank : 657)
Query Neighborhood Hits	608	Target Neighborhood Hits	485	Shared Neighborhood Hits	18
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

BAT2_HUMAN
θ value	4.03905 (rank : 525)	NC score	0.032591 (rank : 518)
Query Neighborhood Hits	608	Target Neighborhood Hits	931	Shared Neighborhood Hits	106
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT3_HUMAN
θ value	4.03905 (rank : 526)	NC score	0.009449 (rank : 584)
Query Neighborhood Hits	608	Target Neighborhood Hits	490	Shared Neighborhood Hits	41
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CGRE1_HUMAN
θ value	4.03905 (rank : 527)	NC score	0.013283 (rank : 563)
Query Neighborhood Hits	608	Target Neighborhood Hits	354	Shared Neighborhood Hits	28
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CO5A2_HUMAN
θ value	4.03905 (rank : 528)	NC score	0.002326 (rank : 638)
Query Neighborhood Hits	608	Target Neighborhood Hits	760	Shared Neighborhood Hits	53
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

DSRAD_MOUSE
θ value	4.03905 (rank : 529)	NC score	0.006539 (rank : 611)
Query Neighborhood Hits	608	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

F10A1_HUMAN
θ value	4.03905 (rank : 530)	NC score	0.004174 (rank : 627)
Query Neighborhood Hits	608	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

GIPC2_MOUSE
θ value	4.03905 (rank : 531)	NC score	0.081594 (rank : 469)
Query Neighborhood Hits	608	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GORS2_HUMAN
θ value	4.03905 (rank : 532)	NC score	0.019517 (rank : 536)
Query Neighborhood Hits	608	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H8Y8, Q96I74, Q96K84, Q9H946, Q9UFW4	Gene names	GORASP2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) (Golgi phosphoprotein 6) (GOLPH6).

GORS2_MOUSE
θ value	4.03905 (rank : 533)	NC score	0.014624 (rank : 558)
Query Neighborhood Hits	608	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

KI21A_MOUSE
θ value	4.03905 (rank : 534)	NC score	-0.005633 (rank : 666)
Query Neighborhood Hits	608	Target Neighborhood Hits	1317	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LGI1_HUMAN
θ value	4.03905 (rank : 535)	NC score	0.359011 (rank : 308)
Query Neighborhood Hits	608	Target Neighborhood Hits	239	Shared Neighborhood Hits	202
SwissProt Accessions	O95970, Q5W001, Q5W002, Q8NI23, Q96LF5	Gene names	LGI1
Domain Architecture
Description	Leucine-rich glioma-inactivated protein 1 precursor (Epitempin-1).

LGI1_MOUSE
θ value	4.03905 (rank : 536)	NC score	0.357858 (rank : 309)
Query Neighborhood Hits	608	Target Neighborhood Hits	239	Shared Neighborhood Hits	202
SwissProt Accessions	Q9JIA1	Gene names	Lgi1
Domain Architecture
Description	Leucine-rich glioma-inactivated protein 1 precursor.

LRC56_HUMAN
θ value	4.03905 (rank : 537)	NC score	0.120130 (rank : 450)
Query Neighborhood Hits	608	Target Neighborhood Hits	165	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

MINT_HUMAN
θ value	4.03905 (rank : 538)	NC score	0.008777 (rank : 593)
Query Neighborhood Hits	608	Target Neighborhood Hits	1291	Shared Neighborhood Hits	91
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NRAP_HUMAN
θ value	4.03905 (rank : 539)	NC score	0.008390 (rank : 597)
Query Neighborhood Hits	608	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

RBM28_HUMAN
θ value	4.03905 (rank : 540)	NC score	-0.002126 (rank : 658)
Query Neighborhood Hits	608	Target Neighborhood Hits	307	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

SAPS1_HUMAN
θ value	4.03905 (rank : 541)	NC score	0.012788 (rank : 565)
Query Neighborhood Hits	608	Target Neighborhood Hits	704	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SI1L1_HUMAN
θ value	4.03905 (rank : 542)	NC score	0.040987 (rank : 506)
Query Neighborhood Hits	608	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
θ value	4.03905 (rank : 543)	NC score	0.040181 (rank : 508)
Query Neighborhood Hits	608	Target Neighborhood Hits	189	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SIPA1_MOUSE
θ value	4.03905 (rank : 544)	NC score	0.022688 (rank : 527)
Query Neighborhood Hits	608	Target Neighborhood Hits	158	Shared Neighborhood Hits	27
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SMOO_HUMAN
θ value	4.03905 (rank : 545)	NC score	0.011881 (rank : 570)
Query Neighborhood Hits	608	Target Neighborhood Hits	391	Shared Neighborhood Hits	49
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

SRRM1_MOUSE
θ value	4.03905 (rank : 546)	NC score	0.033830 (rank : 517)
Query Neighborhood Hits	608	Target Neighborhood Hits	966	Shared Neighborhood Hits	90
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

UBP10_MOUSE
θ value	4.03905 (rank : 547)	NC score	0.007232 (rank : 604)
Query Neighborhood Hits	608	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

ANR11_HUMAN
θ value	5.27518 (rank : 548)	NC score	0.001981 (rank : 643)
Query Neighborhood Hits	608	Target Neighborhood Hits	1289	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ATX2L_HUMAN
θ value	5.27518 (rank : 549)	NC score	0.017013 (rank : 550)
Query Neighborhood Hits	608	Target Neighborhood Hits	443	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BSCL2_MOUSE
θ value	5.27518 (rank : 550)	NC score	0.007681 (rank : 601)
Query Neighborhood Hits	608	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

CIAS1_MOUSE
θ value	5.27518 (rank : 551)	NC score	0.013429 (rank : 562)
Query Neighborhood Hits	608	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

DOCK8_MOUSE
θ value	5.27518 (rank : 552)	NC score	0.002800 (rank : 635)
Query Neighborhood Hits	608	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

EFS_MOUSE
θ value	5.27518 (rank : 553)	NC score	0.008614 (rank : 595)
Query Neighborhood Hits	608	Target Neighborhood Hits	389	Shared Neighborhood Hits	42
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ERIC1_HUMAN
θ value	5.27518 (rank : 554)	NC score	0.006301 (rank : 614)
Query Neighborhood Hits	608	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

F10A5_HUMAN
θ value	5.27518 (rank : 555)	NC score	0.003945 (rank : 628)
Query Neighborhood Hits	608	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

GNAS1_MOUSE
θ value	5.27518 (rank : 556)	NC score	0.004852 (rank : 623)
Query Neighborhood Hits	608	Target Neighborhood Hits	651	Shared Neighborhood Hits	53
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

K0319_HUMAN
θ value	5.27518 (rank : 557)	NC score	0.009837 (rank : 581)
Query Neighborhood Hits	608	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

MDN1_HUMAN
θ value	5.27518 (rank : 558)	NC score	0.008425 (rank : 596)
Query Neighborhood Hits	608	Target Neighborhood Hits	662	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PALB2_HUMAN
θ value	5.27518 (rank : 559)	NC score	0.006616 (rank : 610)
Query Neighborhood Hits	608	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PARPT_MOUSE
θ value	5.27518 (rank : 560)	NC score	0.002482 (rank : 637)
Query Neighborhood Hits	608	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PHLB1_MOUSE
θ value	5.27518 (rank : 561)	NC score	0.011440 (rank : 572)
Query Neighborhood Hits	608	Target Neighborhood Hits	678	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RGNEF_MOUSE
θ value	5.27518 (rank : 562)	NC score	0.015237 (rank : 554)
Query Neighborhood Hits	608	Target Neighborhood Hits	641	Shared Neighborhood Hits	31
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SPEG_MOUSE
θ value	5.27518 (rank : 563)	NC score	0.018712 (rank : 539)
Query Neighborhood Hits	608	Target Neighborhood Hits	1959	Shared Neighborhood Hits	129
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRYG1_MOUSE
θ value	5.27518 (rank : 564)	NC score	-0.007612 (rank : 668)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

ADA30_HUMAN
θ value	6.88961 (rank : 565)	NC score	-0.003268 (rank : 662)
Query Neighborhood Hits	608	Target Neighborhood Hits	391	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADCY4_HUMAN
θ value	6.88961 (rank : 566)	NC score	0.005024 (rank : 621)
Query Neighborhood Hits	608	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFM4, Q96ML7	Gene names	ADCY4
Domain Architecture
Description	Adenylate cyclase type 4 (EC 4.6.1.1) (Adenylate cyclase type IV) (ATP pyrophosphate-lyase 4) (Adenylyl cyclase 4).

ATG4D_HUMAN
θ value	6.88961 (rank : 567)	NC score	0.001946 (rank : 644)
Query Neighborhood Hits	608	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TL0	Gene names	ATG4D, APG4D, AUTL4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).

BSN_MOUSE
θ value	6.88961 (rank : 568)	NC score	0.022472 (rank : 528)
Query Neighborhood Hits	608	Target Neighborhood Hits	2057	Shared Neighborhood Hits	135
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CBL_MOUSE
θ value	6.88961 (rank : 569)	NC score	0.012358 (rank : 569)
Query Neighborhood Hits	608	Target Neighborhood Hits	426	Shared Neighborhood Hits	35
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CGRE1_MOUSE
θ value	6.88961 (rank : 570)	NC score	0.009678 (rank : 583)
Query Neighborhood Hits	608	Target Neighborhood Hits	173	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

COKA1_HUMAN
θ value	6.88961 (rank : 571)	NC score	-0.002598 (rank : 660)
Query Neighborhood Hits	608	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

DAB2_MOUSE
θ value	6.88961 (rank : 572)	NC score	0.006421 (rank : 613)
Query Neighborhood Hits	608	Target Neighborhood Hits	163	Shared Neighborhood Hits	12
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

FOG1_MOUSE
θ value	6.88961 (rank : 573)	NC score	-0.007047 (rank : 667)
Query Neighborhood Hits	608	Target Neighborhood Hits	1237	Shared Neighborhood Hits	60
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GGA1_HUMAN
θ value	6.88961 (rank : 574)	NC score	0.002885 (rank : 634)
Query Neighborhood Hits	608	Target Neighborhood Hits	169	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

LAD1_HUMAN
θ value	6.88961 (rank : 575)	NC score	0.018955 (rank : 538)
Query Neighborhood Hits	608	Target Neighborhood Hits	441	Shared Neighborhood Hits	42
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LGI3_MOUSE
θ value	6.88961 (rank : 576)	NC score	0.347991 (rank : 315)
Query Neighborhood Hits	608	Target Neighborhood Hits	229	Shared Neighborhood Hits	192
SwissProt Accessions	Q8K406	Gene names	Lgi3
Domain Architecture
Description	Leucine-rich repeat LGI family member 3 precursor (Leucine-rich glioma-inactivated protein 3) (Leubrin).

MIME_HUMAN
θ value	6.88961 (rank : 577)	NC score	0.418149 (rank : 279)
Query Neighborhood Hits	608	Target Neighborhood Hits	219	Shared Neighborhood Hits	195
SwissProt Accessions	P20774, Q9UF90, Q9UNK5	Gene names	OGN, OIF
Domain Architecture	No domain graphic available
Description	Mimecan precursor (Osteoglycin) (Osteoinductive factor) (OIF).

PAK4_MOUSE
θ value	6.88961 (rank : 578)	NC score	-0.003600 (rank : 665)
Query Neighborhood Hits	608	Target Neighborhood Hits	1098	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PININ_HUMAN
θ value	6.88961 (rank : 579)	NC score	0.010042 (rank : 578)
Query Neighborhood Hits	608	Target Neighborhood Hits	753	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	6.88961 (rank : 580)	NC score	0.006859 (rank : 606)
Query Neighborhood Hits	608	Target Neighborhood Hits	777	Shared Neighborhood Hits	57
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

REPS1_MOUSE
θ value	6.88961 (rank : 581)	NC score	0.001216 (rank : 647)
Query Neighborhood Hits	608	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SPR1A_MOUSE
θ value	6.88961 (rank : 582)	NC score	0.009950 (rank : 579)
Query Neighborhood Hits	608	Target Neighborhood Hits	343	Shared Neighborhood Hits	28
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SSPO_MOUSE
θ value	6.88961 (rank : 583)	NC score	-0.002325 (rank : 659)
Query Neighborhood Hits	608	Target Neighborhood Hits	800	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SYMPK_MOUSE
θ value	6.88961 (rank : 584)	NC score	0.005568 (rank : 619)
Query Neighborhood Hits	608	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

TLR6_HUMAN
θ value	6.88961 (rank : 585)	NC score	0.429514 (rank : 270)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Y2C9	Gene names	TLR6
Domain Architecture
Description	Toll-like receptor 6 precursor.

UBP2_HUMAN
θ value	6.88961 (rank : 586)	NC score	-0.001406 (rank : 656)
Query Neighborhood Hits	608	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

CI152_HUMAN
θ value	8.99809 (rank : 587)	NC score	0.006858 (rank : 607)
Query Neighborhood Hits	608	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JTZ5	Gene names	C9orf152
Domain Architecture	No domain graphic available
Description	Protein C9orf152.

CO039_MOUSE
θ value	8.99809 (rank : 588)	NC score	0.009215 (rank : 588)
Query Neighborhood Hits	608	Target Neighborhood Hits	445	Shared Neighborhood Hits	39
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

DEAF1_MOUSE
θ value	8.99809 (rank : 589)	NC score	0.002248 (rank : 639)
Query Neighborhood Hits	608	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

DJC12_HUMAN
θ value	8.99809 (rank : 590)	NC score	-0.001117 (rank : 654)
Query Neighborhood Hits	608	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKB3, Q9UKB2	Gene names	DNAJC12, JDP1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

DOCK8_HUMAN
θ value	8.99809 (rank : 591)	NC score	0.002113 (rank : 642)
Query Neighborhood Hits	608	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

EPN2_MOUSE
θ value	8.99809 (rank : 592)	NC score	0.001717 (rank : 645)
Query Neighborhood Hits	608	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

LIRB3_HUMAN
θ value	8.99809 (rank : 593)	NC score	-0.002634 (rank : 661)
Query Neighborhood Hits	608	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

LPP_HUMAN
θ value	8.99809 (rank : 594)	NC score	0.017890 (rank : 543)
Query Neighborhood Hits	608	Target Neighborhood Hits	775	Shared Neighborhood Hits	69
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAML2_HUMAN
θ value	8.99809 (rank : 595)	NC score	0.007356 (rank : 602)
Query Neighborhood Hits	608	Target Neighborhood Hits	360	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MAP1A_HUMAN
θ value	8.99809 (rank : 596)	NC score	0.013019 (rank : 564)
Query Neighborhood Hits	608	Target Neighborhood Hits	1626	Shared Neighborhood Hits	97
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP1B_MOUSE
θ value	8.99809 (rank : 597)	NC score	0.006133 (rank : 615)
Query Neighborhood Hits	608	Target Neighborhood Hits	977	Shared Neighborhood Hits	67
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MCM2_MOUSE
θ value	8.99809 (rank : 598)	NC score	0.001091 (rank : 648)
Query Neighborhood Hits	608	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P97310, O08971, O89057, Q8C2R0	Gene names	Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

MYST3_MOUSE
θ value	8.99809 (rank : 599)	NC score	0.002161 (rank : 640)
Query Neighborhood Hits	608	Target Neighborhood Hits	688	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

OGFR_MOUSE
θ value	8.99809 (rank : 600)	NC score	0.015137 (rank : 555)
Query Neighborhood Hits	608	Target Neighborhood Hits	584	Shared Neighborhood Hits	49
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PGRP2_HUMAN
θ value	8.99809 (rank : 601)	NC score	0.006643 (rank : 609)
Query Neighborhood Hits	608	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PD5, Q96N74, Q9UC60	Gene names	PGLYRP2, PGLYRPL, PGRPL
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2).

RC3H1_HUMAN
θ value	8.99809 (rank : 602)	NC score	0.010390 (rank : 576)
Query Neighborhood Hits	608	Target Neighborhood Hits	433	Shared Neighborhood Hits	32
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RIMB1_MOUSE
θ value	8.99809 (rank : 603)	NC score	0.006830 (rank : 608)
Query Neighborhood Hits	608	Target Neighborhood Hits	1376	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SPHK2_HUMAN
θ value	8.99809 (rank : 604)	NC score	0.003141 (rank : 633)
Query Neighborhood Hits	608	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

WD51A_HUMAN
θ value	8.99809 (rank : 605)	NC score	-0.008804 (rank : 669)
Query Neighborhood Hits	608	Target Neighborhood Hits	337	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

ZEP1_MOUSE
θ value	8.99809 (rank : 606)	NC score	-0.010656 (rank : 671)
Query Neighborhood Hits	608	Target Neighborhood Hits	1063	Shared Neighborhood Hits	50
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZN385_HUMAN
θ value	8.99809 (rank : 607)	NC score	0.003636 (rank : 630)
Query Neighborhood Hits	608	Target Neighborhood Hits	614	Shared Neighborhood Hits	40
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ZN394_HUMAN
θ value	8.99809 (rank : 608)	NC score	-0.015148 (rank : 674)
Query Neighborhood Hits	608	Target Neighborhood Hits	752	Shared Neighborhood Hits	14
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.

AMGO3_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.429368 (rank : 272)
Query Neighborhood Hits	608	Target Neighborhood Hits	276	Shared Neighborhood Hits	194
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

AMGO3_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.437419 (rank : 264)
Query Neighborhood Hits	608	Target Neighborhood Hits	276	Shared Neighborhood Hits	204
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

AN32A_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.132511 (rank : 443)
Query Neighborhood Hits	608	Target Neighborhood Hits	234	Shared Neighborhood Hits	124
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

AN32A_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.143209 (rank : 433)
Query Neighborhood Hits	608	Target Neighborhood Hits	254	Shared Neighborhood Hits	134
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32B_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.115040 (rank : 451)
Query Neighborhood Hits	608	Target Neighborhood Hits	243	Shared Neighborhood Hits	123
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

AN32B_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.071852 (rank : 478)
Query Neighborhood Hits	608	Target Neighborhood Hits	236	Shared Neighborhood Hits	96
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

AN32C_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.143209 (rank : 434)
Query Neighborhood Hits	608	Target Neighborhood Hits	254	Shared Neighborhood Hits	134
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

AN32D_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.077191 (rank : 475)
Query Neighborhood Hits	608	Target Neighborhood Hits	95	Shared Neighborhood Hits	66
SwissProt Accessions	O95626, Q6NTC4	Gene names	ANP32D, PP32R2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2).

AN32E_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.155418 (rank : 425)
Query Neighborhood Hits	608	Target Neighborhood Hits	291	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

AN32E_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.149487 (rank : 427)
Query Neighborhood Hits	608	Target Neighborhood Hits	257	Shared Neighborhood Hits	142
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

CD14_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.072558 (rank : 477)
Query Neighborhood Hits	608	Target Neighborhood Hits	57	Shared Neighborhood Hits	51
SwissProt Accessions	P08571, Q96FR6, Q96L99, Q9UNS3	Gene names	CD14
Domain Architecture	No domain graphic available
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein) [Contains: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane- bound form].

CD14_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.125875 (rank : 449)
Query Neighborhood Hits	608	Target Neighborhood Hits	104	Shared Neighborhood Hits	85
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

CEP72_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.104228 (rank : 460)
Query Neighborhood Hits	608	Target Neighborhood Hits	374	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CEP72_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.094179 (rank : 464)
Query Neighborhood Hits	608	Target Neighborhood Hits	381	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CJ011_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.052372 (rank : 492)
Query Neighborhood Hits	608	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H2I8	Gene names	C10orf11
Domain Architecture	No domain graphic available
Description	Protein C10orf11.

CNKR2_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.065006 (rank : 481)
Query Neighborhood Hits	608	Target Neighborhood Hits	197	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.065025 (rank : 480)
Query Neighborhood Hits	608	Target Neighborhood Hits	197	Shared Neighborhood Hits	58
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CU002_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.129006 (rank : 447)
Query Neighborhood Hits	608	Target Neighborhood Hits	84	Shared Neighborhood Hits	56
SwissProt Accessions	O43822, O14993, Q99837, Q99838	Gene names	C21orf2
Domain Architecture	No domain graphic available
Description	Protein C21orf2 (C21orf-HUMF09G8.5) (YF5/A2).

FSHR_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.229897 (rank : 389)
Query Neighborhood Hits	608	Target Neighborhood Hits	790	Shared Neighborhood Hits	184
SwissProt Accessions	P23945, Q16225	Gene names	FSHR, LGR1
Domain Architecture
Description	Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropin receptor).

FSHR_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.252903 (rank : 377)
Query Neighborhood Hits	608	Target Neighborhood Hits	684	Shared Neighborhood Hits	189
SwissProt Accessions	P35378, Q9D4C2, Q9QWV8	Gene names	Fshr
Domain Architecture
Description	Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropin receptor).

GP124_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.336992 (rank : 316)
Query Neighborhood Hits	608	Target Neighborhood Hits	304	Shared Neighborhood Hits	198
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.313455 (rank : 324)
Query Neighborhood Hits	608	Target Neighborhood Hits	423	Shared Neighborhood Hits	198
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.349961 (rank : 314)
Query Neighborhood Hits	608	Target Neighborhood Hits	329	Shared Neighborhood Hits	197
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP1BB_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.266743 (rank : 372)
Query Neighborhood Hits	608	Target Neighborhood Hits	125	Shared Neighborhood Hits	109
SwissProt Accessions	P13224, Q8NG40	Gene names	GP1BB
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (Antigen CD42b-beta) (CD42c antigen).

GP1BB_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.282289 (rank : 362)
Query Neighborhood Hits	608	Target Neighborhood Hits	136	Shared Neighborhood Hits	118
SwissProt Accessions	P56400	Gene names	Gp1bb
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (CD42c antigen).

GPIX_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.306031 (rank : 329)
Query Neighborhood Hits	608	Target Neighborhood Hits	162	Shared Neighborhood Hits	135
SwissProt Accessions	P14770, Q14445, Q92525	Gene names	GP9
Domain Architecture
Description	Platelet glycoprotein IX precursor (GPIX) (CD42a antigen).

KGUA_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.175783 (rank : 421)
Query Neighborhood Hits	608	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.176899 (rank : 419)
Query Neighborhood Hits	608	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LGI2_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.281372 (rank : 365)
Query Neighborhood Hits	608	Target Neighborhood Hits	200	Shared Neighborhood Hits	165
SwissProt Accessions	Q8K4Z0, Q80T76	Gene names	Lgi2, Kiaa1916
Domain Architecture
Description	Leucine-rich repeat LGI family member 2 precursor (Leucine-rich glioma-inactivated protein 2).

LGI3_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.350515 (rank : 312)
Query Neighborhood Hits	608	Target Neighborhood Hits	228	Shared Neighborhood Hits	192
SwissProt Accessions	Q8N145, Q86TL4, Q8N296	Gene names	LGI3, LGIL4
Domain Architecture
Description	Leucine-rich repeat LGI family member 3 precursor (Leucine-rich glioma-inactivated protein 3) (LGI1-like protein 4).

LMO7_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.094634 (rank : 463)
Query Neighborhood Hits	608	Target Neighborhood Hits	507	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LR37A_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.316452 (rank : 322)
Query Neighborhood Hits	608	Target Neighborhood Hits	720	Shared Neighborhood Hits	237
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LR37B_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.363247 (rank : 307)
Query Neighborhood Hits	608	Target Neighborhood Hits	392	Shared Neighborhood Hits	201
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

LRC19_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.407530 (rank : 287)
Query Neighborhood Hits	608	Target Neighborhood Hits	217	Shared Neighborhood Hits	187
SwissProt Accessions	Q9H756	Gene names	LRRC19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

LRC24_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.439521 (rank : 262)
Query Neighborhood Hits	608	Target Neighborhood Hits	404	Shared Neighborhood Hits	205
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC24_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.437327 (rank : 265)
Query Neighborhood Hits	608	Target Neighborhood Hits	387	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC25_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.057484 (rank : 483)
Query Neighborhood Hits	608	Target Neighborhood Hits	48	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N386, Q8N9A5	Gene names	LRRC25, MAPA
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 25 precursor (Monocyte and plasmacytoid-activated protein).

LRC25_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.104422 (rank : 459)
Query Neighborhood Hits	608	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K1T1, Q3TAD5	Gene names	Lrrc25, Mapa
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 25 precursor (Monocyte and plasmacytoid-activated protein).

LRC31_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.177850 (rank : 418)
Query Neighborhood Hits	608	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

LRC3B_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.387605 (rank : 301)
Query Neighborhood Hits	608	Target Neighborhood Hits	215	Shared Neighborhood Hits	184
SwissProt Accessions	Q96PB8	Gene names	LRRC3B, LRP15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC3B_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.387606 (rank : 300)
Query Neighborhood Hits	608	Target Neighborhood Hits	215	Shared Neighborhood Hits	184
SwissProt Accessions	Q8VCH9	Gene names	Lrrc3b, Lrp15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC46_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.223427 (rank : 397)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	127
SwissProt Accessions	Q96FV0	Gene names	LRRC46
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 46.

LRC46_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.194123 (rank : 406)
Query Neighborhood Hits	608	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	Q9DAP0, Q8R1Z3	Gene names	Lrrc46
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 46.

LRC50_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.241376 (rank : 385)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

LRC50_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.228394 (rank : 390)
Query Neighborhood Hits	608	Target Neighborhood Hits	190	Shared Neighborhood Hits	121
SwissProt Accessions	Q9D2H9, Q9CVS9	Gene names	Lrrc50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

LRC51_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.107700 (rank : 455)
Query Neighborhood Hits	608	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q96E66	Gene names	LRRC51
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 51.

LRC51_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.098845 (rank : 462)
Query Neighborhood Hits	608	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DAK8, Q8R171	Gene names	Lrrc51
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 51.

LRRC3_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.438576 (rank : 263)
Query Neighborhood Hits	608	Target Neighborhood Hits	232	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BY71	Gene names	LRRC3, C21orf102
Domain Architecture
Description	Leucine-rich repeat-containing protein 3 precursor.

LRRC6_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.136326 (rank : 439)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	79
SwissProt Accessions	Q86X45, Q13648, Q4G183	Gene names	LRRC6, LRTP, TSLRP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

LRRC6_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.111440 (rank : 454)
Query Neighborhood Hits	608	Target Neighborhood Hits	110	Shared Neighborhood Hits	55
SwissProt Accessions	O88978, Q9CUG2	Gene names	Lrrc6, Lrtp, Mc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

LSHR_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.133459 (rank : 442)
Query Neighborhood Hits	608	Target Neighborhood Hits	731	Shared Neighborhood Hits	122
SwissProt Accessions	P22888, Q14751, Q15996, Q9UEW9	Gene names	LHCGR, LCGR, LGR2, LHRHR
Domain Architecture
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH- R) (Luteinizing hormone receptor) (LHR).

MFA3L_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.056840 (rank : 485)
Query Neighborhood Hits	608	Target Neighborhood Hits	230	Shared Neighborhood Hits	31
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MFA3L_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.054142 (rank : 489)
Query Neighborhood Hits	608	Target Neighborhood Hits	214	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

NTRK3_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.067416 (rank : 479)
Query Neighborhood Hits	608	Target Neighborhood Hits	1115	Shared Neighborhood Hits	180
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

PDZD8_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.074364 (rank : 476)
Query Neighborhood Hits	608	Target Neighborhood Hits	185	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PKD1_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.313514 (rank : 323)
Query Neighborhood Hits	608	Target Neighborhood Hits	387	Shared Neighborhood Hits	185
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

RHPN2_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.051920 (rank : 494)
Query Neighborhood Hits	608	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RNF41_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.055430 (rank : 488)
Query Neighborhood Hits	608	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.055573 (rank : 487)
Query Neighborhood Hits	608	Target Neighborhood Hits	224	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TBCEL_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.080658 (rank : 471)
Query Neighborhood Hits	608	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q5QJ74	Gene names	LRRC35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

TBCEL_MOUSE
θ value	θ > 10 (rank : 669)	NC score	0.079078 (rank : 474)
Query Neighborhood Hits	608	Target Neighborhood Hits	85	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C5W3, Q8C7A5	Gene names	Lrrc35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

TBCE_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.168736 (rank : 422)
Query Neighborhood Hits	608	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CIV8	Gene names	Tbce
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

TPBG_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.463498 (rank : 243)
Query Neighborhood Hits	608	Target Neighborhood Hits	238	Shared Neighborhood Hits	203
SwissProt Accessions	Q13641	Gene names	TPBG, 5T4
Domain Architecture	No domain graphic available
Description	Trophoblast glycoprotein precursor (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (5T4 oncofetal antigen) (M6P1).

TPBG_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.458268 (rank : 247)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Z0L0, Q6PE98, Q8BQA4	Gene names	Tpbg, 5t4
Domain Architecture	No domain graphic available
Description	Trophoblast glycoprotein precursor (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein).

TSHR_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.104479 (rank : 458)
Query Neighborhood Hits	608	Target Neighborhood Hits	596	Shared Neighborhood Hits	91
SwissProt Accessions	P16473	Gene names	TSHR, LGR3
Domain Architecture
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormone receptor).

TSHR_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.115035 (rank : 452)
Query Neighborhood Hits	608	Target Neighborhood Hits	554	Shared Neighborhood Hits	92
SwissProt Accessions	P47750, Q9D697	Gene names	Tshr
Domain Architecture
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormone receptor).

Hits sorted by NC score

LAP4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	608	Target Neighborhood Hits	608	Shared Neighborhood Hits	608
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
NC score	0.991487 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	608	Target Neighborhood Hits	590	Shared Neighborhood Hits	490
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LRRC7_MOUSE
NC score	0.891728 (rank : 3)	θ value	8.4565e-99 (rank : 8)
Query Neighborhood Hits	608	Target Neighborhood Hits	416	Shared Neighborhood Hits	350
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_HUMAN
NC score	0.890320 (rank : 4)	θ value	8.4565e-99 (rank : 7)
Query Neighborhood Hits	608	Target Neighborhood Hits	423	Shared Neighborhood Hits	348
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LAP2_HUMAN
NC score	0.887087 (rank : 5)	θ value	2.01279e-100 (rank : 6)
Query Neighborhood Hits	608	Target Neighborhood Hits	499	Shared Neighborhood Hits	343
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
NC score	0.885210 (rank : 6)	θ value	3.54468e-105 (rank : 5)
Query Neighborhood Hits	608	Target Neighborhood Hits	482	Shared Neighborhood Hits	336
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LRRC1_HUMAN
NC score	0.820636 (rank : 7)	θ value	7.7336e-177 (rank : 4)
Query Neighborhood Hits	608	Target Neighborhood Hits	282	Shared Neighborhood Hits	238
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRRC1_MOUSE
NC score	0.820242 (rank : 8)	θ value	2.658e-177 (rank : 3)
Query Neighborhood Hits	608	Target Neighborhood Hits	281	Shared Neighborhood Hits	238
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

SHOC2_MOUSE
NC score	0.780504 (rank : 9)	θ value	2.76489e-41 (rank : 9)
Query Neighborhood Hits	608	Target Neighborhood Hits	308	Shared Neighborhood Hits	241
SwissProt Accessions	O88520, Q3UJH6, Q8BVL0	Gene names	Shoc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

SHOC2_HUMAN
NC score	0.780054 (rank : 10)	θ value	6.15952e-41 (rank : 10)
Query Neighborhood Hits	608	Target Neighborhood Hits	330	Shared Neighborhood Hits	239
SwissProt Accessions	Q9UQ13, O76063	Gene names	SHOC2, KIAA0862
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat protein SHOC-2 (Ras-binding protein Sur-8).

LRC40_MOUSE
NC score	0.759275 (rank : 11)	θ value	2.86786e-30 (rank : 20)
Query Neighborhood Hits	608	Target Neighborhood Hits	311	Shared Neighborhood Hits	241
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LRC40_HUMAN
NC score	0.759238 (rank : 12)	θ value	1.02001e-27 (rank : 22)
Query Neighborhood Hits	608	Target Neighborhood Hits	313	Shared Neighborhood Hits	243
SwissProt Accessions	Q9H9A6, Q9BTR7, Q9NSK1, Q9NXC1	Gene names	LRRC40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LRC39_MOUSE
NC score	0.751155 (rank : 13)	θ value	4.43474e-23 (rank : 36)
Query Neighborhood Hits	608	Target Neighborhood Hits	269	Shared Neighborhood Hits	227
SwissProt Accessions	Q8BGI7	Gene names	Lrrc39
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 39.

LRC39_HUMAN
NC score	0.749124 (rank : 14)	θ value	1.80048e-24 (rank : 31)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	220
SwissProt Accessions	Q96DD0, Q5VVK7	Gene names	LRRC39
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 39 (Densin hlg).

RSU1_HUMAN
NC score	0.745949 (rank : 15)	θ value	2.59989e-23 (rank : 35)
Query Neighborhood Hits	608	Target Neighborhood Hits	250	Shared Neighborhood Hits	229
SwissProt Accessions	Q15404	Gene names	RSU1, RSP1
Domain Architecture
Description	Ras suppressor protein 1 (Rsu-1) (RSP-1).

RSU1_MOUSE
NC score	0.745274 (rank : 16)	θ value	4.43474e-23 (rank : 39)
Query Neighborhood Hits	608	Target Neighborhood Hits	239	Shared Neighborhood Hits	224
SwissProt Accessions	Q01730	Gene names	Rsu1, Rsp1
Domain Architecture	No domain graphic available
Description	Ras suppressor protein 1 (Rsu-1) (RSP-1).

LRC57_HUMAN
NC score	0.743636 (rank : 17)	θ value	8.10077e-17 (rank : 71)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N9N7, Q7Z2Z6, Q8N1T6	Gene names	LRRC57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LRC57_MOUSE
NC score	0.742744 (rank : 18)	θ value	3.07829e-16 (rank : 78)
Query Neighborhood Hits	608	Target Neighborhood Hits	267	Shared Neighborhood Hits	236
SwissProt Accessions	Q9D1G5, Q9DC95	Gene names	Lrrc57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LRRC2_HUMAN
NC score	0.721631 (rank : 19)	θ value	9.56915e-18 (rank : 62)
Query Neighborhood Hits	608	Target Neighborhood Hits	229	Shared Neighborhood Hits	214
SwissProt Accessions	Q9BYS8, Q96LT5	Gene names	LRRC2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 2.

LLR1_HUMAN
NC score	0.720103 (rank : 20)	θ value	4.16044e-13 (rank : 123)
Query Neighborhood Hits	608	Target Neighborhood Hits	225	Shared Neighborhood Hits	205
SwissProt Accessions	Q96L50, Q86SZ1, Q8N6H9	Gene names	PPIL5, LRR1
Domain Architecture
Description	Peptidylprolyl isomerase-like 5 (LRR-repeat protein 1) (LRR-1) (4-1BB- mediated signaling molecule) (4-1BBlrr).

LRRC2_MOUSE
NC score	0.712152 (rank : 21)	θ value	5.07402e-19 (rank : 55)
Query Neighborhood Hits	608	Target Neighborhood Hits	238	Shared Neighborhood Hits	216
SwissProt Accessions	Q8VDB8, Q9CX04	Gene names	Lrrc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 2.

LRC18_MOUSE
NC score	0.712112 (rank : 22)	θ value	9.90251e-15 (rank : 102)
Query Neighborhood Hits	608	Target Neighborhood Hits	224	Shared Neighborhood Hits	207
SwissProt Accessions	Q9CQ07, Q6P8T8, Q80ZT3, Q9CW01, Q9DA89	Gene names	Lrrc18, Mtlr1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18 (Testis-specific LRR protein).

LRC10_HUMAN
NC score	0.706604 (rank : 23)	θ value	8.10077e-17 (rank : 70)
Query Neighborhood Hits	608	Target Neighborhood Hits	200	Shared Neighborhood Hits	191
SwissProt Accessions	Q5BKY1, Q6ZVY4	Gene names	LRRC10
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 10.

PIDD_MOUSE
NC score	0.706144 (rank : 24)	θ value	9.24701e-21 (rank : 48)
Query Neighborhood Hits	608	Target Neighborhood Hits	256	Shared Neighborhood Hits	218
SwissProt Accessions	Q9ERV7	Gene names	Lrdd, Pidd
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein.

PIDD_HUMAN
NC score	0.703375 (rank : 25)	θ value	4.15078e-21 (rank : 47)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	219
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

LRC10_MOUSE
NC score	0.702812 (rank : 26)	θ value	9.56915e-18 (rank : 60)
Query Neighborhood Hits	608	Target Neighborhood Hits	191	Shared Neighborhood Hits	184
SwissProt Accessions	Q8K3W2, Q8BUL2	Gene names	Lrrc10, Hrlrrp
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 10 (Heart-restricted leucine- rich repeat protein).

LRC8D_HUMAN
NC score	0.697191 (rank : 27)	θ value	5.23862e-24 (rank : 34)
Query Neighborhood Hits	608	Target Neighborhood Hits	282	Shared Neighborhood Hits	238
SwissProt Accessions	Q7L1W4, Q6UWB2, Q9NVW3	Gene names	LRRC8D, LRRC5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

LRC18_HUMAN
NC score	0.696938 (rank : 28)	θ value	9.90251e-15 (rank : 101)
Query Neighborhood Hits	608	Target Neighborhood Hits	217	Shared Neighborhood Hits	199
SwissProt Accessions	Q8N456, Q6UY02	Gene names	LRRC18
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18.

LRC8D_MOUSE
NC score	0.696491 (rank : 29)	θ value	4.01107e-24 (rank : 32)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	238
SwissProt Accessions	Q8BGR2, Q3UVA9, Q8CI13	Gene names	Lrrc8d, Lrrc5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

PHLPL_MOUSE
NC score	0.695033 (rank : 30)	θ value	4.43474e-23 (rank : 37)
Query Neighborhood Hits	608	Target Neighborhood Hits	303	Shared Neighborhood Hits	238
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

PHLPL_HUMAN
NC score	0.694237 (rank : 31)	θ value	4.9032e-22 (rank : 42)
Query Neighborhood Hits	608	Target Neighborhood Hits	310	Shared Neighborhood Hits	240
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

LRC8A_HUMAN
NC score	0.692011 (rank : 32)	θ value	1.24688e-25 (rank : 27)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	232
SwissProt Accessions	Q8IWT6, Q6UXM2, Q8NCI0, Q9P2B1	Gene names	LRRC8A, KIAA1437, LRRC8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

LRCH4_HUMAN
NC score	0.691127 (rank : 33)	θ value	4.58923e-20 (rank : 51)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	231
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

LRC8A_MOUSE
NC score	0.691106 (rank : 34)	θ value	7.30988e-26 (rank : 25)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	232
SwissProt Accessions	Q80WG5	Gene names	Lrrc8a, Lrrc8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

LRCH4_MOUSE
NC score	0.687922 (rank : 35)	θ value	4.58923e-20 (rank : 52)
Query Neighborhood Hits	608	Target Neighborhood Hits	302	Shared Neighborhood Hits	225
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

LRC8B_HUMAN
NC score	0.687640 (rank : 36)	θ value	4.73814e-25 (rank : 29)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	232
SwissProt Accessions	Q6P9F7, Q6UY21, Q8N106, Q92627	Gene names	LRRC8B, KIAA0231
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8B (T-cell activation leucine repeat-rich protein).

LRC8B_MOUSE
NC score	0.686868 (rank : 37)	θ value	2.87452e-22 (rank : 41)
Query Neighborhood Hits	608	Target Neighborhood Hits	283	Shared Neighborhood Hits	233
SwissProt Accessions	Q5DU41	Gene names	Lrrc8b, Kiaa0231
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8B.

PHLPP_MOUSE
NC score	0.686075 (rank : 38)	θ value	1.86321e-21 (rank : 44)
Query Neighborhood Hits	608	Target Neighborhood Hits	394	Shared Neighborhood Hits	252
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

LRC59_HUMAN
NC score	0.685422 (rank : 39)	θ value	1.47974e-10 (rank : 155)
Query Neighborhood Hits	608	Target Neighborhood Hits	398	Shared Neighborhood Hits	233
SwissProt Accessions	Q96AG4, Q9P189	Gene names	LRRC59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

LRC59_MOUSE
NC score	0.684954 (rank : 40)	θ value	8.67504e-11 (rank : 146)
Query Neighborhood Hits	608	Target Neighborhood Hits	415	Shared Neighborhood Hits	235
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

LRC8E_HUMAN
NC score	0.683028 (rank : 41)	θ value	8.36355e-22 (rank : 43)
Query Neighborhood Hits	608	Target Neighborhood Hits	259	Shared Neighborhood Hits	232
SwissProt Accessions	Q6NSJ5, Q2YDY3, Q7L236, Q8N3B0, Q9H5H8	Gene names	LRRC8E
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

PHLPP_HUMAN
NC score	0.682778 (rank : 42)	θ value	4.43474e-23 (rank : 38)
Query Neighborhood Hits	608	Target Neighborhood Hits	604	Shared Neighborhood Hits	274
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

GPV_MOUSE
NC score	0.675778 (rank : 43)	θ value	1.92365e-26 (rank : 23)
Query Neighborhood Hits	608	Target Neighborhood Hits	293	Shared Neighborhood Hits	243
SwissProt Accessions	O08742	Gene names	Gp5
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

LRC15_MOUSE
NC score	0.672726 (rank : 44)	θ value	2.43343e-21 (rank : 46)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	242
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

LRC47_MOUSE
NC score	0.670917 (rank : 45)	θ value	1.42992e-13 (rank : 116)
Query Neighborhood Hits	608	Target Neighborhood Hits	299	Shared Neighborhood Hits	229
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

GPV_HUMAN
NC score	0.670220 (rank : 46)	θ value	4.02038e-16 (rank : 79)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	239
SwissProt Accessions	P40197	Gene names	GP5
Domain Architecture
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

LRC8C_HUMAN
NC score	0.668032 (rank : 47)	θ value	5.23862e-24 (rank : 33)
Query Neighborhood Hits	608	Target Neighborhood Hits	255	Shared Neighborhood Hits	219
SwissProt Accessions	Q8TDW0, Q9H075	Gene names	LRRC8C, AD158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

LRC8E_MOUSE
NC score	0.667222 (rank : 48)	θ value	1.74391e-19 (rank : 53)
Query Neighborhood Hits	608	Target Neighborhood Hits	256	Shared Neighborhood Hits	232
SwissProt Accessions	Q66JT1	Gene names	Lrrc8e
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

LRC47_HUMAN
NC score	0.667151 (rank : 49)	θ value	2.43908e-13 (rank : 120)
Query Neighborhood Hits	608	Target Neighborhood Hits	300	Shared Neighborhood Hits	230
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LRC15_HUMAN
NC score	0.667147 (rank : 50)	θ value	4.58923e-20 (rank : 50)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	243
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

LRC20_HUMAN
NC score	0.664084 (rank : 51)	θ value	3.41135e-07 (rank : 229)
Query Neighborhood Hits	608	Target Neighborhood Hits	226	Shared Neighborhood Hits	207
SwissProt Accessions	Q8TCA0, Q5T6D4, Q5T6D6, Q9NVA6, Q9NVG3	Gene names	LRRC20
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 20.

A2GL_HUMAN
NC score	0.661039 (rank : 52)	θ value	1.09485e-13 (rank : 113)
Query Neighborhood Hits	608	Target Neighborhood Hits	281	Shared Neighborhood Hits	238
SwissProt Accessions	P02750, Q8N4F5, Q96QZ4	Gene names	LRG1, LRG
Domain Architecture
Description	Leucine-rich alpha-2-glycoprotein precursor (LRG).

CPN2_MOUSE
NC score	0.660509 (rank : 53)	θ value	1.058e-16 (rank : 72)
Query Neighborhood Hits	608	Target Neighborhood Hits	291	Shared Neighborhood Hits	239
SwissProt Accessions	Q9DBB9, Q8R113	Gene names	Cpn2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

LRC8C_MOUSE
NC score	0.660112 (rank : 54)	θ value	7.56453e-23 (rank : 40)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	213
SwissProt Accessions	Q8R502, Q3TEP9, Q8C296, Q8R0N7, Q8R3G5	Gene names	Lrrc8c, Ad158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

CPN2_HUMAN
NC score	0.657713 (rank : 55)	θ value	3.63628e-17 (rank : 65)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	233
SwissProt Accessions	P22792, Q86SU4, Q8N5V4	Gene names	CPN2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

LRC32_HUMAN
NC score	0.657483 (rank : 56)	θ value	1.99529e-15 (rank : 90)
Query Neighborhood Hits	608	Target Neighborhood Hits	303	Shared Neighborhood Hits	243
SwissProt Accessions	Q14392, Q86V06	Gene names	LRRC32, GARP
Domain Architecture
Description	Leucine-rich repeat-containing protein 32 precursor (GARP protein) (Garpin) (Glycoprotein A repetitions predominant).

LRCH3_HUMAN
NC score	0.656408 (rank : 57)	θ value	1.24977e-17 (rank : 63)
Query Neighborhood Hits	608	Target Neighborhood Hits	270	Shared Neighborhood Hits	210
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRC20_MOUSE
NC score	0.654865 (rank : 58)	θ value	1.06045e-08 (rank : 190)
Query Neighborhood Hits	608	Target Neighborhood Hits	220	Shared Neighborhood Hits	199
SwissProt Accessions	Q8CI70	Gene names	Lrrc20
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 20.

FLII_HUMAN
NC score	0.654765 (rank : 59)	θ value	2.51237e-26 (rank : 24)
Query Neighborhood Hits	608	Target Neighborhood Hits	318	Shared Neighborhood Hits	238
SwissProt Accessions	Q13045	Gene names	FLII, FLIL
Domain Architecture
Description	Protein flightless-1 homolog.

FLII_MOUSE
NC score	0.653387 (rank : 60)	θ value	1.24688e-25 (rank : 26)
Query Neighborhood Hits	608	Target Neighborhood Hits	304	Shared Neighborhood Hits	232
SwissProt Accessions	Q9JJ28, Q8K095, Q8VI44	Gene names	Flii, Fli1, Fliih
Domain Architecture	No domain graphic available
Description	Protein flightless-1 homolog.

ALS_HUMAN
NC score	0.652517 (rank : 61)	θ value	3.07829e-16 (rank : 77)
Query Neighborhood Hits	608	Target Neighborhood Hits	280	Shared Neighborhood Hits	238
SwissProt Accessions	P35858	Gene names	IGFALS, ALS
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

LRCH1_HUMAN
NC score	0.649516 (rank : 62)	θ value	7.32683e-18 (rank : 58)
Query Neighborhood Hits	608	Target Neighborhood Hits	266	Shared Neighborhood Hits	199
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

LRCH3_MOUSE
NC score	0.647413 (rank : 63)	θ value	4.74913e-17 (rank : 67)
Query Neighborhood Hits	608	Target Neighborhood Hits	257	Shared Neighborhood Hits	203
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LGR6_HUMAN
NC score	0.645138 (rank : 64)	θ value	1.2105e-12 (rank : 127)
Query Neighborhood Hits	608	Target Neighborhood Hits	344	Shared Neighborhood Hits	240
SwissProt Accessions	Q9HBX8, Q5T509, Q5T512, Q6UY15, Q86VU0, Q96K69, Q9BYD7	Gene names	LGR6
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 6 (VTS20631).

OMGP_HUMAN
NC score	0.644711 (rank : 65)	θ value	9.92553e-07 (rank : 244)
Query Neighborhood Hits	608	Target Neighborhood Hits	268	Shared Neighborhood Hits	233
SwissProt Accessions	P23515	Gene names	OMG, OMGP
Domain Architecture
Description	Oligodendrocyte-myelin glycoprotein precursor.

LRCH1_MOUSE
NC score	0.643137 (rank : 66)	θ value	1.80466e-16 (rank : 74)
Query Neighborhood Hits	608	Target Neighborhood Hits	264	Shared Neighborhood Hits	201
SwissProt Accessions	P62046	Gene names	Lrch1, Chdc1, Kiaa1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1).

TLR11_MOUSE
NC score	0.642402 (rank : 67)	θ value	7.59969e-07 (rank : 241)
Query Neighborhood Hits	608	Target Neighborhood Hits	293	Shared Neighborhood Hits	238
SwissProt Accessions	Q6R5P0	Gene names	Tlr11
Domain Architecture	No domain graphic available
Description	Toll-like receptor 11 precursor.

ALS_MOUSE
NC score	0.640798 (rank : 68)	θ value	1.42992e-13 (rank : 115)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	235
SwissProt Accessions	P70389, Q9DBI7	Gene names	Igfals, Albs, Als
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

OMGP_MOUSE
NC score	0.639954 (rank : 69)	θ value	2.21117e-06 (rank : 252)
Query Neighborhood Hits	608	Target Neighborhood Hits	280	Shared Neighborhood Hits	233
SwissProt Accessions	Q63912	Gene names	Omg, Omgp
Domain Architecture
Description	Oligodendrocyte-myelin glycoprotein precursor.

FMOD_MOUSE
NC score	0.638395 (rank : 70)	θ value	4.30538e-10 (rank : 164)
Query Neighborhood Hits	608	Target Neighborhood Hits	286	Shared Neighborhood Hits	238
SwissProt Accessions	P50608	Gene names	Fmod
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

LRCH2_MOUSE
NC score	0.637297 (rank : 71)	θ value	9.56915e-18 (rank : 61)
Query Neighborhood Hits	608	Target Neighborhood Hits	287	Shared Neighborhood Hits	207
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH2_HUMAN
NC score	0.635797 (rank : 72)	θ value	7.32683e-18 (rank : 59)
Query Neighborhood Hits	608	Target Neighborhood Hits	315	Shared Neighborhood Hits	202
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

ECM2_HUMAN
NC score	0.633963 (rank : 73)	θ value	4.59992e-12 (rank : 130)
Query Neighborhood Hits	608	Target Neighborhood Hits	402	Shared Neighborhood Hits	252
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

LGR5_HUMAN
NC score	0.633602 (rank : 74)	θ value	6.20254e-17 (rank : 69)
Query Neighborhood Hits	608	Target Neighborhood Hits	452	Shared Neighborhood Hits	241
SwissProt Accessions	O75473, Q9UP75	Gene names	LGR5, GPR49, GPR67
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67).

FMOD_HUMAN
NC score	0.630349 (rank : 75)	θ value	1.133e-10 (rank : 147)
Query Neighborhood Hits	608	Target Neighborhood Hits	283	Shared Neighborhood Hits	239
SwissProt Accessions	Q06828, Q15331	Gene names	FMOD, FM
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

LGR4_HUMAN
NC score	0.630204 (rank : 76)	θ value	1.99529e-15 (rank : 89)
Query Neighborhood Hits	608	Target Neighborhood Hits	481	Shared Neighborhood Hits	240
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

GP1BA_HUMAN
NC score	0.629731 (rank : 77)	θ value	7.59969e-07 (rank : 239)
Query Neighborhood Hits	608	Target Neighborhood Hits	407	Shared Neighborhood Hits	243
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

LRTM2_MOUSE
NC score	0.629676 (rank : 78)	θ value	1.16975e-15 (rank : 87)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	231
SwissProt Accessions	Q8BGA3, Q80U08	Gene names	Lrrtm2, Kiaa0416
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor.

OMD_MOUSE
NC score	0.629278 (rank : 79)	θ value	4.76016e-09 (rank : 188)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	233
SwissProt Accessions	O35103	Gene names	Omd
Domain Architecture
Description	Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan sulfate proteoglycan osteomodulin) (KSPG osteomodulin).

LRC33_MOUSE
NC score	0.629251 (rank : 80)	θ value	1.25267e-09 (rank : 168)
Query Neighborhood Hits	608	Target Neighborhood Hits	296	Shared Neighborhood Hits	241
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

TSK_MOUSE
NC score	0.628752 (rank : 81)	θ value	2.79066e-09 (rank : 182)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	230
SwissProt Accessions	Q8CBR6, Q4W655	Gene names	Lrrc54, Tsk
Domain Architecture	No domain graphic available
Description	Tsukushi precursor (Leucine-rich repeat-containing protein 54).

LRTM2_HUMAN
NC score	0.628621 (rank : 82)	θ value	8.95645e-16 (rank : 85)
Query Neighborhood Hits	608	Target Neighborhood Hits	282	Shared Neighborhood Hits	232
SwissProt Accessions	O43300, Q7L770	Gene names	LRRTM2, KIAA0416, LRRN2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor (Leucine-rich repeat neuronal 2 protein).

PRELP_HUMAN
NC score	0.628276 (rank : 83)	θ value	1.42992e-13 (rank : 118)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	239
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

LGR5_MOUSE
NC score	0.628150 (rank : 84)	θ value	1.16975e-15 (rank : 86)
Query Neighborhood Hits	608	Target Neighborhood Hits	484	Shared Neighborhood Hits	242
SwissProt Accessions	Q9Z1P4	Gene names	Lgr5, Fex, Gpr49
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX).

VASN_MOUSE
NC score	0.628147 (rank : 85)	θ value	5.25075e-16 (rank : 83)
Query Neighborhood Hits	608	Target Neighborhood Hits	426	Shared Neighborhood Hits	240
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

LRTM1_HUMAN
NC score	0.627894 (rank : 86)	θ value	2.35696e-16 (rank : 75)
Query Neighborhood Hits	608	Target Neighborhood Hits	273	Shared Neighborhood Hits	238
SwissProt Accessions	Q86UE6, Q96DN1	Gene names	LRRTM1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

LUM_MOUSE
NC score	0.624380 (rank : 87)	θ value	2.79066e-09 (rank : 177)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	237
SwissProt Accessions	P51885, Q3TP25, Q99JZ3, Q9CXK0	Gene names	Lum, Lcn, Ldc
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

CNOT6_MOUSE
NC score	0.622924 (rank : 88)	θ value	4.30538e-10 (rank : 163)
Query Neighborhood Hits	608	Target Neighborhood Hits	229	Shared Neighborhood Hits	210
SwissProt Accessions	Q8K3P5, Q5NCL3, Q80V15	Gene names	Cnot6, Ccr4, Kiaa1194
Domain Architecture
Description	CCR4-NOT transcription complex subunit 6 (EC 3.1.-.-) (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4 homolog) (CCR4 carbon catabolite repression 4-like).

FLRT1_HUMAN
NC score	0.622733 (rank : 89)	θ value	3.52202e-12 (rank : 128)
Query Neighborhood Hits	608	Target Neighborhood Hits	286	Shared Neighborhood Hits	229
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

LRC33_HUMAN
NC score	0.622151 (rank : 90)	θ value	2.79066e-09 (rank : 175)
Query Neighborhood Hits	608	Target Neighborhood Hits	293	Shared Neighborhood Hits	239
SwissProt Accessions	Q86YC3	Gene names	LRRC33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

VASN_HUMAN
NC score	0.622058 (rank : 91)	θ value	1.99529e-15 (rank : 92)
Query Neighborhood Hits	608	Target Neighborhood Hits	449	Shared Neighborhood Hits	234
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

PRELP_MOUSE
NC score	0.621435 (rank : 92)	θ value	2.79066e-09 (rank : 181)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	241
SwissProt Accessions	Q9JK53	Gene names	Prelp
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

LUM_HUMAN
NC score	0.619962 (rank : 93)	θ value	1.63604e-09 (rank : 171)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	238
SwissProt Accessions	P51884, Q96QM7	Gene names	LUM, LDC
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

PGS2_MOUSE
NC score	0.618637 (rank : 94)	θ value	3.76295e-14 (rank : 107)
Query Neighborhood Hits	608	Target Neighborhood Hits	285	Shared Neighborhood Hits	239
SwissProt Accessions	P28654	Gene names	Dcn
Domain Architecture
Description	Decorin precursor (Bone proteoglycan II) (PG-S2) (PG40).

TSK_HUMAN
NC score	0.616836 (rank : 95)	θ value	1.17247e-07 (rank : 217)
Query Neighborhood Hits	608	Target Neighborhood Hits	268	Shared Neighborhood Hits	230
SwissProt Accessions	Q8WUA8, Q6UXK1, Q9UG10, Q9UJX9	Gene names	LRRC54, E2IG4, TSK
Domain Architecture	No domain graphic available
Description	Tsukushi precursor (Leucine-rich repeat-containing protein 54) (E2- induced gene 4 protein).

OMD_HUMAN
NC score	0.615643 (rank : 96)	θ value	1.17247e-07 (rank : 211)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	234
SwissProt Accessions	Q99983	Gene names	OMD
Domain Architecture
Description	Osteomodulin precursor (Osteoadherin) (OSAD) (Keratan sulfate proteoglycan osteomodulin) (KSPG osteomodulin).

CNOT6_HUMAN
NC score	0.614991 (rank : 97)	θ value	5.62301e-10 (rank : 166)
Query Neighborhood Hits	608	Target Neighborhood Hits	225	Shared Neighborhood Hits	207
SwissProt Accessions	Q9ULM6	Gene names	CNOT6, CCR4, KIAA1194
Domain Architecture
Description	CCR4-NOT transcription complex subunit 6 (EC 3.1.-.-) (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4 homolog) (CCR4 carbon catabolite repression 4-like).

LRTM1_MOUSE
NC score	0.613328 (rank : 98)	θ value	1.99529e-15 (rank : 91)
Query Neighborhood Hits	608	Target Neighborhood Hits	264	Shared Neighborhood Hits	230
SwissProt Accessions	Q8K377, Q3UVX1	Gene names	Lrrtm1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

PP1R7_HUMAN
NC score	0.612544 (rank : 99)	θ value	1.133e-10 (rank : 148)
Query Neighborhood Hits	608	Target Neighborhood Hits	265	Shared Neighborhood Hits	207
SwissProt Accessions	Q15435, Q9UQE5, Q9UQE6, Q9Y6K4	Gene names	PPP1R7, SDS22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

FLRT3_HUMAN
NC score	0.610794 (rank : 100)	θ value	9.90251e-15 (rank : 100)
Query Neighborhood Hits	608	Target Neighborhood Hits	281	Shared Neighborhood Hits	230
SwissProt Accessions	Q9NZU0, Q96K39, Q96K42, Q96KB1, Q9P259	Gene names	FLRT3, KIAA1469
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT3 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 3).

ASPN_HUMAN
NC score	0.606810 (rank : 101)	θ value	1.33837e-11 (rank : 135)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	239
SwissProt Accessions	Q9BXN1, Q96K79, Q96LD0, Q9NXP3	Gene names	ASPN, PLAP1
Domain Architecture
Description	Asporin precursor (Periodontal ligament-associated protein 1) (PLAP- 1).

PGS1_MOUSE
NC score	0.603758 (rank : 102)	θ value	2.43908e-13 (rank : 121)
Query Neighborhood Hits	608	Target Neighborhood Hits	265	Shared Neighborhood Hits	227
SwissProt Accessions	P28653, Q61355	Gene names	Bgn
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

LRC27_MOUSE
NC score	0.603092 (rank : 103)	θ value	6.87365e-08 (rank : 204)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	214
SwissProt Accessions	Q80YS5, Q9D6Z2	Gene names	Lrrc27
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

PP1R7_MOUSE
NC score	0.600397 (rank : 104)	θ value	2.13673e-09 (rank : 172)
Query Neighborhood Hits	608	Target Neighborhood Hits	256	Shared Neighborhood Hits	205
SwissProt Accessions	Q3UM45, Q9CV31, Q9Z105	Gene names	Ppp1r7, Sds22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

ASPN_MOUSE
NC score	0.599093 (rank : 105)	θ value	6.00763e-12 (rank : 132)
Query Neighborhood Hits	608	Target Neighborhood Hits	277	Shared Neighborhood Hits	238
SwissProt Accessions	Q99MQ4, Q9D6A2	Gene names	Aspn
Domain Architecture
Description	Asporin precursor.

PGS1_HUMAN
NC score	0.598740 (rank : 106)	θ value	4.16044e-13 (rank : 124)
Query Neighborhood Hits	608	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	P21810, P13247	Gene names	BGN
Domain Architecture
Description	Biglycan precursor (Bone/cartilage proteoglycan I) (PG-S1).

CHAD_MOUSE
NC score	0.597877 (rank : 107)	θ value	3.08544e-08 (rank : 195)
Query Neighborhood Hits	608	Target Neighborhood Hits	260	Shared Neighborhood Hits	226
SwissProt Accessions	O55226	Gene names	Chad
Domain Architecture
Description	Chondroadherin precursor (Cartilage leucine-rich protein).

FLRT2_HUMAN
NC score	0.591585 (rank : 108)	θ value	1.02475e-11 (rank : 134)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	227
SwissProt Accessions	O43155	Gene names	FLRT2, KIAA0405
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT2 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 2).

TLR13_MOUSE
NC score	0.589774 (rank : 109)	θ value	2.13673e-09 (rank : 173)
Query Neighborhood Hits	608	Target Neighborhood Hits	335	Shared Neighborhood Hits	241
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

CHAD_HUMAN
NC score	0.588343 (rank : 110)	θ value	3.41135e-07 (rank : 228)
Query Neighborhood Hits	608	Target Neighborhood Hits	267	Shared Neighborhood Hits	231
SwissProt Accessions	O15335, Q96RJ5	Gene names	CHAD
Domain Architecture
Description	Chondroadherin precursor (Cartilage leucine-rich protein).

LRTM4_MOUSE
NC score	0.584438 (rank : 111)	θ value	8.38298e-14 (rank : 112)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	229
SwissProt Accessions	Q80XG9, Q8C030, Q8JZS8	Gene names	Lrrtm4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

LRTM4_HUMAN
NC score	0.584283 (rank : 112)	θ value	6.41864e-14 (rank : 110)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	227
SwissProt Accessions	Q86VH4	Gene names	LRRTM4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

KERA_HUMAN
NC score	0.581546 (rank : 113)	θ value	4.1701e-05 (rank : 279)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	232
SwissProt Accessions	O60938	Gene names	KERA
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

LRTM3_HUMAN
NC score	0.580659 (rank : 114)	θ value	2.98157e-11 (rank : 138)
Query Neighborhood Hits	608	Target Neighborhood Hits	276	Shared Neighborhood Hits	227
SwissProt Accessions	Q86VH5, Q6N0A3	Gene names	LRRTM3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

PGS2_HUMAN
NC score	0.580241 (rank : 115)	θ value	1.25267e-09 (rank : 169)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	233
SwissProt Accessions	P07585, Q9P0Z0, Q9P0Z1, Q9Y5N8, Q9Y5N9	Gene names	DCN
Domain Architecture
Description	Decorin precursor (Bone proteoglycan II) (PG-S2) (PG40).

LRTM3_MOUSE
NC score	0.578975 (rank : 116)	θ value	5.08577e-11 (rank : 141)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	227
SwissProt Accessions	Q8BZ81, Q3TQA3, Q8BGJ7	Gene names	Lrrtm3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

TLR3_HUMAN
NC score	0.573357 (rank : 117)	θ value	0.00175202 (rank : 334)
Query Neighborhood Hits	608	Target Neighborhood Hits	323	Shared Neighborhood Hits	242
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

KERA_MOUSE
NC score	0.571845 (rank : 118)	θ value	0.000461057 (rank : 309)
Query Neighborhood Hits	608	Target Neighborhood Hits	264	Shared Neighborhood Hits	226
SwissProt Accessions	O35367	Gene names	Kera, Ktcn
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

TLR7_HUMAN
NC score	0.565027 (rank : 119)	θ value	9.92553e-07 (rank : 245)
Query Neighborhood Hits	608	Target Neighborhood Hits	312	Shared Neighborhood Hits	238
SwissProt Accessions	Q9NYK1, Q9NR98	Gene names	TLR7
Domain Architecture
Description	Toll-like receptor 7 precursor.

TLR7_MOUSE
NC score	0.563316 (rank : 120)	θ value	9.92553e-07 (rank : 246)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	239
SwissProt Accessions	P58681, Q923I1	Gene names	Tlr7
Domain Architecture
Description	Toll-like receptor 7 precursor.

SYJ2B_HUMAN
NC score	0.562587 (rank : 121)	θ value	3.52202e-12 (rank : 129)
Query Neighborhood Hits	608	Target Neighborhood Hits	162	Shared Neighborhood Hits	161
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

NYX_HUMAN
NC score	0.556024 (rank : 122)	θ value	3.08544e-08 (rank : 196)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	208
SwissProt Accessions	Q9GZU5, Q5H983, Q9H4J0	Gene names	NYX, CLRP
Domain Architecture
Description	Nyctalopin precursor.

R4RL2_HUMAN
NC score	0.554678 (rank : 123)	θ value	1.133e-10 (rank : 149)
Query Neighborhood Hits	608	Target Neighborhood Hits	273	Shared Neighborhood Hits	227
SwissProt Accessions	Q86UN3, Q6X813	Gene names	RTN4RL2, NGRH1, NGRL3
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 2 precursor (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2) (Nogo receptor-like 3).

TLR5_HUMAN
NC score	0.552149 (rank : 124)	θ value	6.87365e-08 (rank : 207)
Query Neighborhood Hits	608	Target Neighborhood Hits	288	Shared Neighborhood Hits	228
SwissProt Accessions	O60602, O15456	Gene names	TLR5, TIL3
Domain Architecture
Description	Toll-like receptor 5 precursor (Toll/interleukin-1 receptor-like protein 3).

NGL1_MOUSE
NC score	0.551609 (rank : 125)	θ value	6.64225e-11 (rank : 143)
Query Neighborhood Hits	608	Target Neighborhood Hits	512	Shared Neighborhood Hits	236
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_HUMAN
NC score	0.551453 (rank : 126)	θ value	6.64225e-11 (rank : 142)
Query Neighborhood Hits	608	Target Neighborhood Hits	511	Shared Neighborhood Hits	236
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

MPDZ_MOUSE
NC score	0.551118 (rank : 127)	θ value	6.37413e-38 (rank : 14)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	208
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MPDZ_HUMAN
NC score	0.549745 (rank : 128)	θ value	1.6247e-33 (rank : 16)
Query Neighborhood Hits	608	Target Neighborhood Hits	261	Shared Neighborhood Hits	206
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NYX_MOUSE
NC score	0.548868 (rank : 129)	θ value	1.53129e-07 (rank : 220)
Query Neighborhood Hits	608	Target Neighborhood Hits	241	Shared Neighborhood Hits	207
SwissProt Accessions	P83503, Q8BYN4	Gene names	Nyx
Domain Architecture
Description	Nyctalopin precursor.

INADL_MOUSE
NC score	0.548765 (rank : 130)	θ value	2.42779e-29 (rank : 21)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	201
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

R4RL2_MOUSE
NC score	0.548730 (rank : 131)	θ value	1.133e-10 (rank : 150)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	227
SwissProt Accessions	Q7M6Z0, Q3UQ62	Gene names	Rtn4rl2, Ngrl3
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 2 precursor (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2) (Nogo receptor-like 3).

INADL_HUMAN
NC score	0.548483 (rank : 132)	θ value	1.16434e-31 (rank : 18)
Query Neighborhood Hits	608	Target Neighborhood Hits	260	Shared Neighborhood Hits	195
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

TLR3_MOUSE
NC score	0.547327 (rank : 133)	θ value	0.00390308 (rank : 354)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	234
SwissProt Accessions	Q99MB1, Q91ZM4	Gene names	Tlr3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

LRC4B_MOUSE
NC score	0.547111 (rank : 134)	θ value	8.67504e-11 (rank : 145)
Query Neighborhood Hits	608	Target Neighborhood Hits	484	Shared Neighborhood Hits	234
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

AMGO1_MOUSE
NC score	0.546898 (rank : 135)	θ value	2.79066e-09 (rank : 174)
Query Neighborhood Hits	608	Target Neighborhood Hits	325	Shared Neighborhood Hits	226
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

CT075_MOUSE
NC score	0.546802 (rank : 136)	θ value	0.000270298 (rank : 297)
Query Neighborhood Hits	608	Target Neighborhood Hits	358	Shared Neighborhood Hits	234
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

RTN4R_HUMAN
NC score	0.546756 (rank : 137)	θ value	1.80886e-08 (rank : 194)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	225
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

AMGO1_HUMAN
NC score	0.545825 (rank : 138)	θ value	4.76016e-09 (rank : 185)
Query Neighborhood Hits	608	Target Neighborhood Hits	353	Shared Neighborhood Hits	226
SwissProt Accessions	Q86WK6, Q8IW71, Q9ULQ7	Gene names	AMIGO1, ALI2, AMIGO, KIAA1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

LRC4B_HUMAN
NC score	0.545589 (rank : 139)	θ value	2.52405e-10 (rank : 162)
Query Neighborhood Hits	608	Target Neighborhood Hits	479	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

TLR5_MOUSE
NC score	0.545567 (rank : 140)	θ value	1.25267e-09 (rank : 170)
Query Neighborhood Hits	608	Target Neighborhood Hits	287	Shared Neighborhood Hits	227
SwissProt Accessions	Q9JLF7	Gene names	Tlr5
Domain Architecture
Description	Toll-like receptor 5 precursor.

LRRN1_MOUSE
NC score	0.544054 (rank : 141)	θ value	2.61198e-07 (rank : 226)
Query Neighborhood Hits	608	Target Neighborhood Hits	508	Shared Neighborhood Hits	231
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

TLR9_HUMAN
NC score	0.543617 (rank : 142)	θ value	4.92598e-06 (rank : 261)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	231
SwissProt Accessions	Q9NR96, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2, Q9NYC3	Gene names	TLR9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LRRN1_HUMAN
NC score	0.536567 (rank : 143)	θ value	7.59969e-07 (rank : 240)
Query Neighborhood Hits	608	Target Neighborhood Hits	518	Shared Neighborhood Hits	233
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

AMGO2_MOUSE
NC score	0.533961 (rank : 144)	θ value	0.0252991 (rank : 376)
Query Neighborhood Hits	608	Target Neighborhood Hits	329	Shared Neighborhood Hits	230
SwissProt Accessions	Q80ZD9	Gene names	Amigo2, Ali1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1).

LRRN5_HUMAN
NC score	0.532806 (rank : 145)	θ value	5.26297e-08 (rank : 201)
Query Neighborhood Hits	608	Target Neighborhood Hits	493	Shared Neighborhood Hits	234
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

TLR8_MOUSE
NC score	0.531982 (rank : 146)	θ value	5.44631e-05 (rank : 285)
Query Neighborhood Hits	608	Target Neighborhood Hits	297	Shared Neighborhood Hits	234
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

LRC55_MOUSE
NC score	0.530537 (rank : 147)	θ value	6.43352e-06 (rank : 262)
Query Neighborhood Hits	608	Target Neighborhood Hits	254	Shared Neighborhood Hits	223
SwissProt Accessions	Q3UY51	Gene names	Lrrc55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

TLR8_HUMAN
NC score	0.529628 (rank : 148)	θ value	0.00390308 (rank : 355)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	235
SwissProt Accessions	Q9NR97, Q6UXL6, Q9NYG9	Gene names	TLR8
Domain Architecture
Description	Toll-like receptor 8 precursor.

AMGO2_HUMAN
NC score	0.529136 (rank : 149)	θ value	0.000158464 (rank : 290)
Query Neighborhood Hits	608	Target Neighborhood Hits	357	Shared Neighborhood Hits	224
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

LRRN3_MOUSE
NC score	0.528171 (rank : 150)	θ value	2.44474e-05 (rank : 271)
Query Neighborhood Hits	608	Target Neighborhood Hits	455	Shared Neighborhood Hits	226
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

TLR9_MOUSE
NC score	0.527296 (rank : 151)	θ value	4.0297e-08 (rank : 200)
Query Neighborhood Hits	608	Target Neighborhood Hits	291	Shared Neighborhood Hits	233
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LRRC4_MOUSE
NC score	0.526766 (rank : 152)	θ value	1.69304e-06 (rank : 249)
Query Neighborhood Hits	608	Target Neighborhood Hits	412	Shared Neighborhood Hits	225
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

LRSM1_MOUSE
NC score	0.526599 (rank : 153)	θ value	1.42992e-13 (rank : 117)
Query Neighborhood Hits	608	Target Neighborhood Hits	874	Shared Neighborhood Hits	221
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

CD180_MOUSE
NC score	0.525303 (rank : 154)	θ value	0.000786445 (rank : 316)
Query Neighborhood Hits	608	Target Neighborhood Hits	283	Shared Neighborhood Hits	230
SwissProt Accessions	Q62192	Gene names	Cd180, Ly78, Rp105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 78) (Radioprotective 105 kDa protein).

LRFN5_HUMAN
NC score	0.524575 (rank : 155)	θ value	5.81887e-07 (rank : 236)
Query Neighborhood Hits	608	Target Neighborhood Hits	464	Shared Neighborhood Hits	236
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

PDZD7_HUMAN
NC score	0.524512 (rank : 156)	θ value	3.76295e-14 (rank : 106)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	175
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

TX1B3_HUMAN
NC score	0.524075 (rank : 157)	θ value	2.79066e-09 (rank : 183)
Query Neighborhood Hits	608	Target Neighborhood Hits	161	Shared Neighborhood Hits	156
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

SLIK6_HUMAN
NC score	0.523608 (rank : 158)	θ value	3.19293e-05 (rank : 277)
Query Neighborhood Hits	608	Target Neighborhood Hits	297	Shared Neighborhood Hits	237
SwissProt Accessions	Q9H5Y7, Q495Q0, Q6AW93, Q9HAA8, Q9NT60	Gene names	SLITRK6
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 6 precursor.

TLR12_MOUSE
NC score	0.523590 (rank : 159)	θ value	2.44474e-05 (rank : 272)
Query Neighborhood Hits	608	Target Neighborhood Hits	268	Shared Neighborhood Hits	217
SwissProt Accessions	Q6QNU9	Gene names	Tlr12
Domain Architecture	No domain graphic available
Description	Toll-like receptor 12 precursor.

RXFP2_MOUSE
NC score	0.523588 (rank : 160)	θ value	6.87365e-08 (rank : 205)
Query Neighborhood Hits	608	Target Neighborhood Hits	760	Shared Neighborhood Hits	232
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

LRFN5_MOUSE
NC score	0.522599 (rank : 161)	θ value	5.81887e-07 (rank : 237)
Query Neighborhood Hits	608	Target Neighborhood Hits	472	Shared Neighborhood Hits	236
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

SLIK4_MOUSE
NC score	0.522375 (rank : 162)	θ value	2.88788e-06 (rank : 255)
Query Neighborhood Hits	608	Target Neighborhood Hits	292	Shared Neighborhood Hits	238
SwissProt Accessions	Q810B8, Q8BL56, Q8BWB0, Q8BYG4, Q8C056	Gene names	Slitrk4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

LRRC4_HUMAN
NC score	0.521999 (rank : 163)	θ value	1.69304e-06 (rank : 248)
Query Neighborhood Hits	608	Target Neighborhood Hits	444	Shared Neighborhood Hits	225
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

TX1B3_MOUSE
NC score	0.521591 (rank : 164)	θ value	2.79066e-09 (rank : 184)
Query Neighborhood Hits	608	Target Neighborhood Hits	158	Shared Neighborhood Hits	153
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

CD180_HUMAN
NC score	0.521475 (rank : 165)	θ value	0.0148317 (rank : 371)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	228
SwissProt Accessions	Q99467	Gene names	CD180, LY64, RP105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 64) (Radioprotective 105 kDa protein).

SLIK4_HUMAN
NC score	0.521374 (rank : 166)	θ value	1.09739e-05 (rank : 265)
Query Neighborhood Hits	608	Target Neighborhood Hits	287	Shared Neighborhood Hits	236
SwissProt Accessions	Q8IW52, Q8TCM8, Q96DL3	Gene names	SLITRK4
Domain Architecture
Description	SLIT and NTRK-like protein 4 precursor.

R4RL1_HUMAN
NC score	0.521196 (rank : 167)	θ value	4.92598e-06 (rank : 260)
Query Neighborhood Hits	608	Target Neighborhood Hits	240	Shared Neighborhood Hits	211
SwissProt Accessions	Q86UN2, Q8ND46	Gene names	RTN4RL1, NGRH2, NGRL2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

SLIK6_MOUSE
NC score	0.520478 (rank : 168)	θ value	4.1701e-05 (rank : 283)
Query Neighborhood Hits	608	Target Neighborhood Hits	302	Shared Neighborhood Hits	237
SwissProt Accessions	Q8C110, Q8BLL0	Gene names	Slitrk6, Sltk6
Domain Architecture
Description	SLIT and NTRK-like protein 6 precursor.

DLG4_MOUSE
NC score	0.520287 (rank : 169)	θ value	1.98146e-39 (rank : 12)
Query Neighborhood Hits	608	Target Neighborhood Hits	282	Shared Neighborhood Hits	187
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.519368 (rank : 170)	θ value	1.98146e-39 (rank : 11)
Query Neighborhood Hits	608	Target Neighborhood Hits	286	Shared Neighborhood Hits	185
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

SLIK1_HUMAN
NC score	0.519153 (rank : 171)	θ value	4.45536e-07 (rank : 232)
Query Neighborhood Hits	608	Target Neighborhood Hits	297	Shared Neighborhood Hits	238
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

USH1C_HUMAN
NC score	0.518844 (rank : 172)	θ value	2.43908e-13 (rank : 122)
Query Neighborhood Hits	608	Target Neighborhood Hits	327	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

SLIK1_MOUSE
NC score	0.518357 (rank : 173)	θ value	4.45536e-07 (rank : 233)
Query Neighborhood Hits	608	Target Neighborhood Hits	333	Shared Neighborhood Hits	242
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

LRFN3_HUMAN
NC score	0.517180 (rank : 174)	θ value	4.76016e-09 (rank : 186)
Query Neighborhood Hits	608	Target Neighborhood Hits	444	Shared Neighborhood Hits	233
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRRN3_HUMAN
NC score	0.515576 (rank : 175)	θ value	2.21117e-06 (rank : 251)
Query Neighborhood Hits	608	Target Neighborhood Hits	461	Shared Neighborhood Hits	227
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRC55_HUMAN
NC score	0.515435 (rank : 176)	θ value	1.38821 (rank : 473)
Query Neighborhood Hits	608	Target Neighborhood Hits	257	Shared Neighborhood Hits	226
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

TLR4_HUMAN
NC score	0.515351 (rank : 177)	θ value	2.44474e-05 (rank : 274)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	234
SwissProt Accessions	O00206, Q9UK78, Q9UM57	Gene names	TLR4
Domain Architecture
Description	Toll-like receptor 4 precursor (hToll) (CD284 antigen).

LIN7B_HUMAN
NC score	0.513738 (rank : 178)	θ value	1.9326e-10 (rank : 156)
Query Neighborhood Hits	608	Target Neighborhood Hits	200	Shared Neighborhood Hits	190
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LRFN3_MOUSE
NC score	0.512072 (rank : 179)	θ value	4.76016e-09 (rank : 187)
Query Neighborhood Hits	608	Target Neighborhood Hits	455	Shared Neighborhood Hits	231
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LIN7B_MOUSE
NC score	0.511890 (rank : 180)	θ value	2.52405e-10 (rank : 161)
Query Neighborhood Hits	608	Target Neighborhood Hits	200	Shared Neighborhood Hits	190
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7A_MOUSE
NC score	0.511632 (rank : 181)	θ value	1.47974e-10 (rank : 154)
Query Neighborhood Hits	608	Target Neighborhood Hits	193	Shared Neighborhood Hits	188
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7A_HUMAN
NC score	0.511542 (rank : 182)	θ value	1.47974e-10 (rank : 153)
Query Neighborhood Hits	608	Target Neighborhood Hits	193	Shared Neighborhood Hits	188
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

DLG1_HUMAN
NC score	0.510548 (rank : 183)	θ value	1.28434e-38 (rank : 13)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	176
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

OPT_MOUSE
NC score	0.510214 (rank : 184)	θ value	0.000121331 (rank : 289)
Query Neighborhood Hits	608	Target Neighborhood Hits	240	Shared Neighborhood Hits	217
SwissProt Accessions	Q920A0, Q91ZZ9	Gene names	Optc, Opt
Domain Architecture
Description	Opticin precursor (Oculoglycan).

LRC27_HUMAN
NC score	0.510045 (rank : 185)	θ value	8.40245e-06 (rank : 263)
Query Neighborhood Hits	608	Target Neighborhood Hits	710	Shared Neighborhood Hits	237
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

LIN7C_HUMAN
NC score	0.509330 (rank : 186)	θ value	1.9326e-10 (rank : 157)
Query Neighborhood Hits	608	Target Neighborhood Hits	198	Shared Neighborhood Hits	190
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.509330 (rank : 187)	θ value	1.9326e-10 (rank : 158)
Query Neighborhood Hits	608	Target Neighborhood Hits	198	Shared Neighborhood Hits	190
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

DLG1_MOUSE
NC score	0.508865 (rank : 188)	θ value	4.568e-36 (rank : 15)
Query Neighborhood Hits	608	Target Neighborhood Hits	285	Shared Neighborhood Hits	176
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG2_HUMAN
NC score	0.508733 (rank : 189)	θ value	1.37539e-32 (rank : 17)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	183
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_MOUSE
NC score	0.507449 (rank : 190)	θ value	1.98606e-31 (rank : 19)
Query Neighborhood Hits	608	Target Neighborhood Hits	274	Shared Neighborhood Hits	184
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

LRC21_MOUSE
NC score	0.506264 (rank : 191)	θ value	4.92598e-06 (rank : 259)
Query Neighborhood Hits	608	Target Neighborhood Hits	462	Shared Neighborhood Hits	226
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRIG3_HUMAN
NC score	0.506054 (rank : 192)	θ value	6.41864e-14 (rank : 109)
Query Neighborhood Hits	608	Target Neighborhood Hits	601	Shared Neighborhood Hits	243
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

RXFP2_HUMAN
NC score	0.505113 (rank : 193)	θ value	8.97725e-08 (rank : 209)
Query Neighborhood Hits	608	Target Neighborhood Hits	736	Shared Neighborhood Hits	234
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

SLIK2_MOUSE
NC score	0.504940 (rank : 194)	θ value	1.17247e-07 (rank : 214)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	235
SwissProt Accessions	Q810C0, Q8BXL6	Gene names	Slitrk2
Domain Architecture
Description	SLIT and NTRK-like protein 2 precursor.

LRFN4_MOUSE
NC score	0.504319 (rank : 195)	θ value	2.79066e-09 (rank : 176)
Query Neighborhood Hits	608	Target Neighborhood Hits	442	Shared Neighborhood Hits	228
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRC17_MOUSE
NC score	0.504085 (rank : 196)	θ value	0.00228821 (rank : 335)
Query Neighborhood Hits	608	Target Neighborhood Hits	268	Shared Neighborhood Hits	218
SwissProt Accessions	Q9CXD9	Gene names	Lrrc17
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor.

DLG2_MOUSE
NC score	0.503902 (rank : 197)	θ value	2.12685e-25 (rank : 28)
Query Neighborhood Hits	608	Target Neighborhood Hits	271	Shared Neighborhood Hits	182
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG3_HUMAN
NC score	0.503880 (rank : 198)	θ value	1.80048e-24 (rank : 30)
Query Neighborhood Hits	608	Target Neighborhood Hits	269	Shared Neighborhood Hits	184
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

RTN4R_MOUSE
NC score	0.503768 (rank : 199)	θ value	0.0330416 (rank : 387)
Query Neighborhood Hits	608	Target Neighborhood Hits	293	Shared Neighborhood Hits	229
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

LRFN4_HUMAN
NC score	0.503657 (rank : 200)	θ value	7.34386e-10 (rank : 167)
Query Neighborhood Hits	608	Target Neighborhood Hits	462	Shared Neighborhood Hits	229
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRIG3_MOUSE
NC score	0.502716 (rank : 201)	θ value	4.44505e-15 (rank : 97)
Query Neighborhood Hits	608	Target Neighborhood Hits	611	Shared Neighborhood Hits	246
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

WHRN_HUMAN
NC score	0.501145 (rank : 202)	θ value	1.42992e-13 (rank : 119)
Query Neighborhood Hits	608	Target Neighborhood Hits	325	Shared Neighborhood Hits	206
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

GRIP2_HUMAN
NC score	0.500607 (rank : 203)	θ value	3.63628e-17 (rank : 66)
Query Neighborhood Hits	608	Target Neighborhood Hits	256	Shared Neighborhood Hits	204
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

R4RL1_MOUSE
NC score	0.500593 (rank : 204)	θ value	9.29e-05 (rank : 286)
Query Neighborhood Hits	608	Target Neighborhood Hits	235	Shared Neighborhood Hits	199
SwissProt Accessions	Q8K0S5	Gene names	Rtn4rl1, Ngrl2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

RXFP1_HUMAN
NC score	0.498213 (rank : 205)	θ value	5.26297e-08 (rank : 203)
Query Neighborhood Hits	608	Target Neighborhood Hits	816	Shared Neighborhood Hits	245
SwissProt Accessions	Q9HBX9	Gene names	RXFP1, LGR7
Domain Architecture
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-rich repeat-containing G-protein coupled receptor 7).

WHRN_MOUSE
NC score	0.498188 (rank : 206)	θ value	6.41864e-14 (rank : 111)
Query Neighborhood Hits	608	Target Neighborhood Hits	412	Shared Neighborhood Hits	214
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZ11_HUMAN
NC score	0.498181 (rank : 207)	θ value	1.17247e-07 (rank : 212)
Query Neighborhood Hits	608	Target Neighborhood Hits	160	Shared Neighborhood Hits	155
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SLIK2_HUMAN
NC score	0.498064 (rank : 208)	θ value	3.41135e-07 (rank : 230)
Query Neighborhood Hits	608	Target Neighborhood Hits	285	Shared Neighborhood Hits	235
SwissProt Accessions	Q9H156, Q5JXB1, Q8NBC7, Q96JH3	Gene names	SLITRK2, CXorf2, KIAA1854, SLITL1
Domain Architecture
Description	SLIT and NTRK-like protein 2 precursor.

SLIK5_MOUSE
NC score	0.498040 (rank : 209)	θ value	2.21117e-06 (rank : 253)
Query Neighborhood Hits	608	Target Neighborhood Hits	301	Shared Neighborhood Hits	237
SwissProt Accessions	Q810B7, Q9CT21	Gene names	Slitrk5
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor.

SLIK5_HUMAN
NC score	0.497813 (rank : 210)	θ value	2.88788e-06 (rank : 256)
Query Neighborhood Hits	608	Target Neighborhood Hits	302	Shared Neighborhood Hits	236
SwissProt Accessions	O94991	Gene names	SLITRK5, KIAA0918, LRRC11
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor (Leucine-rich repeat-containing protein 11).

OPT_HUMAN
NC score	0.495739 (rank : 211)	θ value	0.00869519 (rank : 366)
Query Neighborhood Hits	608	Target Neighborhood Hits	255	Shared Neighborhood Hits	217
SwissProt Accessions	Q9UBM4	Gene names	OPTC, OPT
Domain Architecture	No domain graphic available
Description	Opticin precursor (Oculoglycan).

PDZ11_MOUSE
NC score	0.495445 (rank : 212)	θ value	1.17247e-07 (rank : 213)
Query Neighborhood Hits	608	Target Neighborhood Hits	154	Shared Neighborhood Hits	148
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

GRIP1_HUMAN
NC score	0.492708 (rank : 213)	θ value	1.99529e-15 (rank : 88)
Query Neighborhood Hits	608	Target Neighborhood Hits	231	Shared Neighborhood Hits	197
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
NC score	0.491696 (rank : 214)	θ value	4.44505e-15 (rank : 96)
Query Neighborhood Hits	608	Target Neighborhood Hits	241	Shared Neighborhood Hits	198
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

LRC21_HUMAN
NC score	0.491640 (rank : 215)	θ value	1.43324e-05 (rank : 268)
Query Neighborhood Hits	608	Target Neighborhood Hits	456	Shared Neighborhood Hits	221
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

SLIK3_HUMAN
NC score	0.490910 (rank : 216)	θ value	0.000270298 (rank : 303)
Query Neighborhood Hits	608	Target Neighborhood Hits	298	Shared Neighborhood Hits	235
SwissProt Accessions	O94933	Gene names	SLITRK3, KIAA0848
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 3 precursor.

SLIK3_MOUSE
NC score	0.489808 (rank : 217)	θ value	0.000602161 (rank : 313)
Query Neighborhood Hits	608	Target Neighborhood Hits	308	Shared Neighborhood Hits	236
SwissProt Accessions	Q810B9	Gene names	Slitrk3
Domain Architecture
Description	SLIT and NTRK-like protein 3 precursor.

LRC17_HUMAN
NC score	0.489277 (rank : 218)	θ value	0.0330416 (rank : 383)
Query Neighborhood Hits	608	Target Neighborhood Hits	267	Shared Neighborhood Hits	221
SwissProt Accessions	Q8N6Y2, Q13288, Q6UWA7, Q75MG5	Gene names	LRRC17, P37NB
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor (p37NB).

LRSM1_HUMAN
NC score	0.489020 (rank : 219)	θ value	3.76295e-14 (rank : 104)
Query Neighborhood Hits	608	Target Neighborhood Hits	1078	Shared Neighborhood Hits	229
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PAR3L_HUMAN
NC score	0.488508 (rank : 220)	θ value	2.60593e-15 (rank : 93)
Query Neighborhood Hits	608	Target Neighborhood Hits	297	Shared Neighborhood Hits	159
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDZD1_MOUSE
NC score	0.488094 (rank : 221)	θ value	2.60593e-15 (rank : 94)
Query Neighborhood Hits	608	Target Neighborhood Hits	191	Shared Neighborhood Hits	170
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LRFN2_HUMAN
NC score	0.486388 (rank : 222)	θ value	1.06045e-08 (rank : 191)
Query Neighborhood Hits	608	Target Neighborhood Hits	450	Shared Neighborhood Hits	227
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LNX2_MOUSE
NC score	0.484708 (rank : 223)	θ value	2.97466e-19 (rank : 54)
Query Neighborhood Hits	608	Target Neighborhood Hits	407	Shared Neighborhood Hits	185
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LRFN2_MOUSE
NC score	0.484166 (rank : 224)	θ value	1.06045e-08 (rank : 192)
Query Neighborhood Hits	608	Target Neighborhood Hits	450	Shared Neighborhood Hits	225
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

PGLB_HUMAN
NC score	0.483741 (rank : 225)	θ value	0.00869519 (rank : 367)
Query Neighborhood Hits	608	Target Neighborhood Hits	250	Shared Neighborhood Hits	218
SwissProt Accessions	Q99645, Q8NEJ5	Gene names	DSPG3, PGLB
Domain Architecture
Description	Dermatan sulfate proteoglycan 3 precursor (Epiphycan) (Small chondroitin/dermatan sulfate proteoglycan) (Proteoglycan-Lb) (PG-Lb).

USH1C_MOUSE
NC score	0.481917 (rank : 226)	θ value	6.00763e-12 (rank : 133)
Query Neighborhood Hits	608	Target Neighborhood Hits	557	Shared Neighborhood Hits	217
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

CT075_HUMAN
NC score	0.480051 (rank : 227)	θ value	0.00175202 (rank : 332)
Query Neighborhood Hits	608	Target Neighborhood Hits	387	Shared Neighborhood Hits	228
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

LRIG1_MOUSE
NC score	0.479967 (rank : 228)	θ value	2.20605e-14 (rank : 103)
Query Neighborhood Hits	608	Target Neighborhood Hits	627	Shared Neighborhood Hits	244
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

PARD3_HUMAN
NC score	0.479579 (rank : 229)	θ value	3.76295e-14 (rank : 105)
Query Neighborhood Hits	608	Target Neighborhood Hits	312	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

LRIG2_MOUSE
NC score	0.479317 (rank : 230)	θ value	1.33837e-11 (rank : 136)
Query Neighborhood Hits	608	Target Neighborhood Hits	586	Shared Neighborhood Hits	239
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

PARD3_MOUSE
NC score	0.479105 (rank : 231)	θ value	7.58209e-15 (rank : 99)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	176
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDZD1_HUMAN
NC score	0.476261 (rank : 232)	θ value	4.91457e-14 (rank : 108)
Query Neighborhood Hits	608	Target Neighborhood Hits	190	Shared Neighborhood Hits	169
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LNX1_MOUSE
NC score	0.474769 (rank : 233)	θ value	1.2077e-20 (rank : 49)
Query Neighborhood Hits	608	Target Neighborhood Hits	377	Shared Neighborhood Hits	182
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MIME_MOUSE
NC score	0.474391 (rank : 234)	θ value	0.163984 (rank : 417)
Query Neighborhood Hits	608	Target Neighborhood Hits	234	Shared Neighborhood Hits	208
SwissProt Accessions	Q62000	Gene names	Ogn, Og
Domain Architecture
Description	Mimecan precursor (Osteoglycin).

LRIG2_HUMAN
NC score	0.472596 (rank : 235)	θ value	5.08577e-11 (rank : 140)
Query Neighborhood Hits	608	Target Neighborhood Hits	595	Shared Neighborhood Hits	241
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LNX1_HUMAN
NC score	0.472568 (rank : 236)	θ value	2.43343e-21 (rank : 45)
Query Neighborhood Hits	608	Target Neighborhood Hits	379	Shared Neighborhood Hits	174
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TLR4_MOUSE
NC score	0.471145 (rank : 237)	θ value	0.813845 (rank : 463)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	223
SwissProt Accessions	Q9QUK6, Q9D691, Q9QZF5, Q9Z203	Gene names	Tlr4, Lps
Domain Architecture
Description	Toll-like receptor 4 precursor (CD284 antigen).

LRC52_MOUSE
NC score	0.470365 (rank : 238)	θ value	0.163984 (rank : 415)
Query Neighborhood Hits	608	Target Neighborhood Hits	240	Shared Neighborhood Hits	209
SwissProt Accessions	Q5M8M9	Gene names	Lrrc52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

PGLB_MOUSE
NC score	0.470147 (rank : 239)	θ value	0.0736092 (rank : 397)
Query Neighborhood Hits	608	Target Neighborhood Hits	243	Shared Neighborhood Hits	212
SwissProt Accessions	P70186	Gene names	Dspg3, Pglb
Domain Architecture
Description	Dermatan sulfate proteoglycan 3 precursor (Epiphycan) (Small chondroitin/dermatan sulfate proteoglycan) (Proteoglycan-Lb) (PG-Lb).

PDZD2_HUMAN
NC score	0.470082 (rank : 240)	θ value	1.09485e-13 (rank : 114)
Query Neighborhood Hits	608	Target Neighborhood Hits	772	Shared Neighborhood Hits	227
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LNX2_HUMAN
NC score	0.468273 (rank : 241)	θ value	5.25075e-16 (rank : 81)
Query Neighborhood Hits	608	Target Neighborhood Hits	389	Shared Neighborhood Hits	183
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TLR1_MOUSE
NC score	0.466329 (rank : 242)	θ value	2.44474e-05 (rank : 273)
Query Neighborhood Hits	608	Target Neighborhood Hits	286	Shared Neighborhood Hits	235
SwissProt Accessions	Q9EPQ1, Q9EPW5	Gene names	Tlr1
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

TPBG_HUMAN
NC score	0.463498 (rank : 243)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	608	Target Neighborhood Hits	238	Shared Neighborhood Hits	203
SwissProt Accessions	Q13641	Gene names	TPBG, 5T4
Domain Architecture	No domain graphic available
Description	Trophoblast glycoprotein precursor (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (5T4 oncofetal antigen) (M6P1).

LRIG1_HUMAN
NC score	0.461224 (rank : 244)	θ value	7.09661e-13 (rank : 126)
Query Neighborhood Hits	608	Target Neighborhood Hits	654	Shared Neighborhood Hits	248
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRC52_HUMAN
NC score	0.460837 (rank : 245)	θ value	0.279714 (rank : 435)
Query Neighborhood Hits	608	Target Neighborhood Hits	229	Shared Neighborhood Hits	201
SwissProt Accessions	Q8N7C0, Q5T9K5	Gene names	LRRC52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

NHERF_MOUSE
NC score	0.459249 (rank : 246)	θ value	1.9326e-10 (rank : 159)
Query Neighborhood Hits	608	Target Neighborhood Hits	195	Shared Neighborhood Hits	172
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

TPBG_MOUSE
NC score	0.458268 (rank : 247)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Z0L0, Q6PE98, Q8BQA4	Gene names	Tpbg, 5t4
Domain Architecture	No domain graphic available
Description	Trophoblast glycoprotein precursor (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein).

TLR2_MOUSE
NC score	0.458203 (rank : 248)	θ value	0.0330416 (rank : 389)
Query Neighborhood Hits	608	Target Neighborhood Hits	283	Shared Neighborhood Hits	225
SwissProt Accessions	Q9QUN7, Q3U400, Q9DBC4	Gene names	Tlr2
Domain Architecture
Description	Toll-like receptor 2 precursor (CD282 antigen).

IL16_HUMAN
NC score	0.457384 (rank : 249)	θ value	2.52405e-10 (rank : 160)
Query Neighborhood Hits	608	Target Neighborhood Hits	207	Shared Neighborhood Hits	152
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

TLR2_HUMAN
NC score	0.455593 (rank : 250)	θ value	0.00228821 (rank : 339)
Query Neighborhood Hits	608	Target Neighborhood Hits	290	Shared Neighborhood Hits	229
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

MAGI1_HUMAN
NC score	0.455530 (rank : 251)	θ value	2.35696e-16 (rank : 76)
Query Neighborhood Hits	608	Target Neighborhood Hits	388	Shared Neighborhood Hits	213
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

LRC19_MOUSE
NC score	0.451528 (rank : 252)	θ value	0.00665767 (rank : 359)
Query Neighborhood Hits	608	Target Neighborhood Hits	238	Shared Neighborhood Hits	203
SwissProt Accessions	Q8BZT5, Q6P8J1	Gene names	Lrrc19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

MAGI1_MOUSE
NC score	0.450594 (rank : 253)	θ value	7.58209e-15 (rank : 98)
Query Neighborhood Hits	608	Target Neighborhood Hits	403	Shared Neighborhood Hits	213
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

NHRF2_HUMAN
NC score	0.450190 (rank : 254)	θ value	6.64225e-11 (rank : 144)
Query Neighborhood Hits	608	Target Neighborhood Hits	197	Shared Neighborhood Hits	179
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

LRC49_MOUSE
NC score	0.449531 (rank : 255)	θ value	0.00298849 (rank : 343)
Query Neighborhood Hits	608	Target Neighborhood Hits	230	Shared Neighborhood Hits	187
SwissProt Accessions	Q91YK0, Q8C3S4, Q8C7T7	Gene names	Lrrc49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79).

TLR10_HUMAN
NC score	0.448812 (rank : 256)	θ value	0.00390308 (rank : 353)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	235
SwissProt Accessions	Q9BXR5, Q5FWG4, Q6UXL3	Gene names	TLR10
Domain Architecture
Description	Toll-like receptor 10 precursor.

PDZD3_HUMAN
NC score	0.448100 (rank : 257)	θ value	5.43371e-13 (rank : 125)
Query Neighborhood Hits	608	Target Neighborhood Hits	180	Shared Neighborhood Hits	172
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

TLR6_MOUSE
NC score	0.447786 (rank : 258)	θ value	0.00035302 (rank : 305)
Query Neighborhood Hits	608	Target Neighborhood Hits	288	Shared Neighborhood Hits	233
SwissProt Accessions	Q9EPW9, Q9WTQ4	Gene names	Tlr6
Domain Architecture
Description	Toll-like receptor 6 precursor.

NHERF_HUMAN
NC score	0.445946 (rank : 259)	θ value	2.79066e-09 (rank : 179)
Query Neighborhood Hits	608	Target Neighborhood Hits	190	Shared Neighborhood Hits	169
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_MOUSE
NC score	0.442328 (rank : 260)	θ value	2.79066e-09 (rank : 180)
Query Neighborhood Hits	608	Target Neighborhood Hits	194	Shared Neighborhood Hits	178
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

LRRC3_MOUSE
NC score	0.439862 (rank : 261)	θ value	0.62314 (rank : 450)
Query Neighborhood Hits	608	Target Neighborhood Hits	236	Shared Neighborhood Hits	203
SwissProt Accessions	P59034	Gene names	Lrrc3
Domain Architecture
Description	Leucine-rich repeat-containing protein 3 precursor.

LRC24_HUMAN
NC score	0.439521 (rank : 262)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	608	Target Neighborhood Hits	404	Shared Neighborhood Hits	205
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRRC3_HUMAN
NC score	0.438576 (rank : 263)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	608	Target Neighborhood Hits	232	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BY71	Gene names	LRRC3, C21orf102
Domain Architecture
Description	Leucine-rich repeat-containing protein 3 precursor.

AMGO3_MOUSE
NC score	0.437419 (rank : 264)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	608	Target Neighborhood Hits	276	Shared Neighborhood Hits	204
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

LRC24_MOUSE
NC score	0.437327 (rank : 265)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	608	Target Neighborhood Hits	387	Shared Neighborhood Hits	197
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

IL16_MOUSE
NC score	0.434869 (rank : 266)	θ value	3.77169e-06 (rank : 258)
Query Neighborhood Hits	608	Target Neighborhood Hits	189	Shared Neighborhood Hits	145
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

GOPC_MOUSE
NC score	0.433718 (rank : 267)	θ value	1.53129e-07 (rank : 219)
Query Neighborhood Hits	608	Target Neighborhood Hits	323	Shared Neighborhood Hits	178
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

MAGI2_HUMAN
NC score	0.430366 (rank : 268)	θ value	4.30538e-10 (rank : 165)
Query Neighborhood Hits	608	Target Neighborhood Hits	373	Shared Neighborhood Hits	208
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PDZD3_MOUSE
NC score	0.429904 (rank : 269)	θ value	3.89403e-11 (rank : 139)
Query Neighborhood Hits	608	Target Neighborhood Hits	171	Shared Neighborhood Hits	168
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

TLR6_HUMAN
NC score	0.429514 (rank : 270)	θ value	6.88961 (rank : 585)
Query Neighborhood Hits	608	Target Neighborhood Hits	284	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Y2C9	Gene names	TLR6
Domain Architecture
Description	Toll-like receptor 6 precursor.

TLR1_HUMAN
NC score	0.429485 (rank : 271)	θ value	0.0252991 (rank : 381)
Query Neighborhood Hits	608	Target Neighborhood Hits	280	Shared Neighborhood Hits	223
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

AMGO3_HUMAN
NC score	0.429368 (rank : 272)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	608	Target Neighborhood Hits	276	Shared Neighborhood Hits	194
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

MAGI2_MOUSE
NC score	0.427712 (rank : 273)	θ value	2.79066e-09 (rank : 178)
Query Neighborhood Hits	608	Target Neighborhood Hits	370	Shared Neighborhood Hits	202
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

GOPC_HUMAN
NC score	0.426947 (rank : 274)	θ value	1.53129e-07 (rank : 218)
Query Neighborhood Hits	608	Target Neighborhood Hits	377	Shared Neighborhood Hits	179
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

SLIT3_HUMAN
NC score	0.425017 (rank : 275)	θ value	8.97725e-08 (rank : 210)
Query Neighborhood Hits	608	Target Neighborhood Hits	682	Shared Neighborhood Hits	243
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

ZO3_MOUSE
NC score	0.424521 (rank : 276)	θ value	2.61198e-07 (rank : 227)
Query Neighborhood Hits	608	Target Neighborhood Hits	224	Shared Neighborhood Hits	188
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SLIT3_MOUSE
NC score	0.424260 (rank : 277)	θ value	3.08544e-08 (rank : 197)
Query Neighborhood Hits	608	Target Neighborhood Hits	700	Shared Neighborhood Hits	244
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

PZRN4_HUMAN
NC score	0.423630 (rank : 278)	θ value	5.07402e-19 (rank : 56)
Query Neighborhood Hits	608	Target Neighborhood Hits	438	Shared Neighborhood Hits	165
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

MIME_HUMAN
NC score	0.418149 (rank : 279)	θ value	6.88961 (rank : 577)
Query Neighborhood Hits	608	Target Neighborhood Hits	219	Shared Neighborhood Hits	195
SwissProt Accessions	P20774, Q9UF90, Q9UNK5	Gene names	OGN, OIF
Domain Architecture	No domain graphic available
Description	Mimecan precursor (Osteoglycin) (Osteoinductive factor) (OIF).

SLIT2_MOUSE
NC score	0.417883 (rank : 280)	θ value	1.133e-10 (rank : 152)
Query Neighborhood Hits	608	Target Neighborhood Hits	684	Shared Neighborhood Hits	243
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ZO3_HUMAN
NC score	0.417228 (rank : 281)	θ value	3.19293e-05 (rank : 278)
Query Neighborhood Hits	608	Target Neighborhood Hits	219	Shared Neighborhood Hits	180
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SLIT2_HUMAN
NC score	0.414271 (rank : 282)	θ value	1.133e-10 (rank : 151)
Query Neighborhood Hits	608	Target Neighborhood Hits	708	Shared Neighborhood Hits	242
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SNTG2_HUMAN
NC score	0.413945 (rank : 283)	θ value	5.81887e-07 (rank : 238)
Query Neighborhood Hits	608	Target Neighborhood Hits	191	Shared Neighborhood Hits	181
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PZRN3_MOUSE
NC score	0.411829 (rank : 284)	θ value	4.74913e-17 (rank : 68)
Query Neighborhood Hits	608	Target Neighborhood Hits	447	Shared Neighborhood Hits	163
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.410745 (rank : 285)	θ value	4.02038e-16 (rank : 80)
Query Neighborhood Hits	608	Target Neighborhood Hits	461	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ZO1_MOUSE
NC score	0.410018 (rank : 286)	θ value	4.59992e-12 (rank : 131)
Query Neighborhood Hits	608	Target Neighborhood Hits	453	Shared Neighborhood Hits	202
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LRC19_HUMAN
NC score	0.407530 (rank : 287)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	608	Target Neighborhood Hits	217	Shared Neighborhood Hits	187
SwissProt Accessions	Q9H756	Gene names	LRRC19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

SNTB2_HUMAN
NC score	0.406847 (rank : 288)	θ value	4.0297e-08 (rank : 198)
Query Neighborhood Hits	608	Target Neighborhood Hits	180	Shared Neighborhood Hits	165
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

LRC49_HUMAN
NC score	0.405336 (rank : 289)	θ value	0.0148317 (rank : 372)
Query Neighborhood Hits	608	Target Neighborhood Hits	210	Shared Neighborhood Hits	164
SwissProt Accessions	Q8IUZ0, Q9NXM6	Gene names	LRRC49
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4).

SNTB2_MOUSE
NC score	0.405327 (rank : 290)	θ value	4.0297e-08 (rank : 199)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	165
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

ZO1_HUMAN
NC score	0.403317 (rank : 291)	θ value	2.28291e-11 (rank : 137)
Query Neighborhood Hits	608	Target Neighborhood Hits	474	Shared Neighborhood Hits	195
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
NC score	0.402593 (rank : 292)	θ value	1.38499e-08 (rank : 193)
Query Neighborhood Hits	608	Target Neighborhood Hits	289	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

SLIT1_HUMAN
NC score	0.402155 (rank : 293)	θ value	1.53129e-07 (rank : 221)
Query Neighborhood Hits	608	Target Neighborhood Hits	700	Shared Neighborhood Hits	243
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
NC score	0.399654 (rank : 294)	θ value	4.45536e-07 (rank : 234)
Query Neighborhood Hits	608	Target Neighborhood Hits	715	Shared Neighborhood Hits	240
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ZO2_MOUSE
NC score	0.399305 (rank : 295)	θ value	7.59969e-07 (rank : 242)
Query Neighborhood Hits	608	Target Neighborhood Hits	296	Shared Neighborhood Hits	184
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

SNTG2_MOUSE
NC score	0.393184 (rank : 296)	θ value	2.88788e-06 (rank : 257)
Query Neighborhood Hits	608	Target Neighborhood Hits	176	Shared Neighborhood Hits	169
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG1_MOUSE
NC score	0.391363 (rank : 297)	θ value	1.53129e-07 (rank : 222)
Query Neighborhood Hits	608	Target Neighborhood Hits	179	Shared Neighborhood Hits	173
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
NC score	0.391243 (rank : 298)	θ value	1.99992e-07 (rank : 225)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTA1_HUMAN
NC score	0.390512 (rank : 299)	θ value	6.87365e-08 (rank : 206)
Query Neighborhood Hits	608	Target Neighborhood Hits	186	Shared Neighborhood Hits	170
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

LRC3B_MOUSE
NC score	0.387606 (rank : 300)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	608	Target Neighborhood Hits	215	Shared Neighborhood Hits	184
SwissProt Accessions	Q8VCH9	Gene names	Lrrc3b, Lrp15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC3B_HUMAN
NC score	0.387605 (rank : 301)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	608	Target Neighborhood Hits	215	Shared Neighborhood Hits	184
SwissProt Accessions	Q96PB8	Gene names	LRRC3B, LRP15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

SNTA1_MOUSE
NC score	0.384061 (rank : 302)	θ value	1.69304e-06 (rank : 250)
Query Neighborhood Hits	608	Target Neighborhood Hits	170	Shared Neighborhood Hits	164
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

LGI4_HUMAN
NC score	0.383011 (rank : 303)	θ value	0.279714 (rank : 433)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	209
SwissProt Accessions	Q8N135	Gene names	LGI4, LGIL3
Domain Architecture
Description	Leucine-rich repeat LGI family member 4 precursor (Leucine-rich glioma-inactivated protein 4) (LGI1-like protein 3).

LGI2_HUMAN
NC score	0.380801 (rank : 304)	θ value	0.365318 (rank : 442)
Query Neighborhood Hits	608	Target Neighborhood Hits	232	Shared Neighborhood Hits	200
SwissProt Accessions	Q8N0V4, Q8NDW6, Q96PX2, Q9NVK4	Gene names	LGI2, KIAA1916, LGIL2
Domain Architecture
Description	Leucine-rich repeat LGI family member 2 precursor (Leucine-rich glioma-inactivated protein 2) (LGI1-like protein 2).

SNTB1_HUMAN
NC score	0.377528 (rank : 305)	θ value	1.17247e-07 (rank : 215)
Query Neighborhood Hits	608	Target Neighborhood Hits	157	Shared Neighborhood Hits	152
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.376789 (rank : 306)	θ value	1.17247e-07 (rank : 216)
Query Neighborhood Hits	608	Target Neighborhood Hits	160	Shared Neighborhood Hits	151
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

LR37B_HUMAN
NC score	0.363247 (rank : 307)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	608	Target Neighborhood Hits	392	Shared Neighborhood Hits	201
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

LGI1_HUMAN
NC score	0.359011 (rank : 308)	θ value	4.03905 (rank : 535)
Query Neighborhood Hits	608	Target Neighborhood Hits	239	Shared Neighborhood Hits	202
SwissProt Accessions	O95970, Q5W001, Q5W002, Q8NI23, Q96LF5	Gene names	LGI1
Domain Architecture
Description	Leucine-rich glioma-inactivated protein 1 precursor (Epitempin-1).

LGI1_MOUSE
NC score	0.357858 (rank : 309)	θ value	4.03905 (rank : 536)
Query Neighborhood Hits	608	Target Neighborhood Hits	239	Shared Neighborhood Hits	202
SwissProt Accessions	Q9JIA1	Gene names	Lgi1
Domain Architecture
Description	Leucine-rich glioma-inactivated protein 1 precursor.

LGI4_MOUSE
NC score	0.350961 (rank : 310)	θ value	3.0926 (rank : 515)
Query Neighborhood Hits	608	Target Neighborhood Hits	228	Shared Neighborhood Hits	197
SwissProt Accessions	Q8K1S1, Q8K4Y8	Gene names	Lgi4, Lgil3
Domain Architecture
Description	Leucine-rich repeat LGI family member 4 precursor (Leucine-rich glioma-inactivated protein 4) (LGI1-like protein 3).

K1849_HUMAN
NC score	0.350726 (rank : 311)	θ value	9.92553e-07 (rank : 243)
Query Neighborhood Hits	608	Target Neighborhood Hits	220	Shared Neighborhood Hits	153
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LGI3_HUMAN
NC score	0.350515 (rank : 312)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	608	Target Neighborhood Hits	228	Shared Neighborhood Hits	192
SwissProt Accessions	Q8N145, Q86TL4, Q8N296	Gene names	LGI3, LGIL4
Domain Architecture
Description	Leucine-rich repeat LGI family member 3 precursor (Leucine-rich glioma-inactivated protein 3) (LGI1-like protein 4).

LRC48_HUMAN
NC score	0.350224 (rank : 313)	θ value	0.0961366 (rank : 402)
Query Neighborhood Hits	608	Target Neighborhood Hits	324	Shared Neighborhood Hits	157
SwissProt Accessions	Q9H069, Q86SF9, Q86W73, Q8IWG0	Gene names	LRRC48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

GP125_MOUSE
NC score	0.349961 (rank : 314)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	608	Target Neighborhood Hits	329	Shared Neighborhood Hits	197
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

LGI3_MOUSE
NC score	0.347991 (rank : 315)	θ value	6.88961 (rank : 576)
Query Neighborhood Hits	608	Target Neighborhood Hits	229	Shared Neighborhood Hits	192
SwissProt Accessions	Q8K406	Gene names	Lgi3
Domain Architecture
Description	Leucine-rich repeat LGI family member 3 precursor (Leucine-rich glioma-inactivated protein 3) (Leubrin).

GP124_HUMAN
NC score	0.336992 (rank : 316)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	608	Target Neighborhood Hits	304	Shared Neighborhood Hits	198
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
NC score	0.336026 (rank : 317)	θ value	0.0961366 (rank : 400)
Query Neighborhood Hits	608	Target Neighborhood Hits	327	Shared Neighborhood Hits	195
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

LRC48_MOUSE
NC score	0.333901 (rank : 318)	θ value	0.0113563 (rank : 368)
Query Neighborhood Hits	608	Target Neighborhood Hits	252	Shared Neighborhood Hits	152
SwissProt Accessions	Q9D5E4	Gene names	Lrrc48
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 48.

K1849_MOUSE
NC score	0.332213 (rank : 319)	θ value	0.00020696 (rank : 295)
Query Neighborhood Hits	608	Target Neighborhood Hits	335	Shared Neighborhood Hits	158
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MPP4_HUMAN
NC score	0.328307 (rank : 320)	θ value	5.26297e-08 (rank : 202)
Query Neighborhood Hits	608	Target Neighborhood Hits	205	Shared Neighborhood Hits	140
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PGTA_HUMAN
NC score	0.322612 (rank : 321)	θ value	0.163984 (rank : 418)
Query Neighborhood Hits	608	Target Neighborhood Hits	160	Shared Neighborhood Hits	128
SwissProt Accessions	Q92696	Gene names	RABGGTA
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

LR37A_HUMAN
NC score	0.316452 (rank : 322)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	608	Target Neighborhood Hits	720	Shared Neighborhood Hits	237
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

PKD1_HUMAN
NC score	0.313514 (rank : 323)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	608	Target Neighborhood Hits	387	Shared Neighborhood Hits	185
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

GP124_MOUSE
NC score	0.313455 (rank : 324)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	608	Target Neighborhood Hits	423	Shared Neighborhood Hits	198
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

DLG5_HUMAN
NC score	0.311757 (rank : 325)	θ value	6.21693e-09 (rank : 189)
Query Neighborhood Hits	608	Target Neighborhood Hits	1088	Shared Neighborhood Hits	208
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

LRRK2_MOUSE
NC score	0.309714 (rank : 326)	θ value	1.38178e-16 (rank : 73)
Query Neighborhood Hits	608	Target Neighborhood Hits	1359	Shared Neighborhood Hits	249
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

PDZK4_MOUSE
NC score	0.309356 (rank : 327)	θ value	0.00298849 (rank : 345)
Query Neighborhood Hits	608	Target Neighborhood Hits	165	Shared Neighborhood Hits	131
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_HUMAN
NC score	0.308081 (rank : 328)	θ value	0.00390308 (rank : 351)
Query Neighborhood Hits	608	Target Neighborhood Hits	165	Shared Neighborhood Hits	126
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

GPIX_HUMAN
NC score	0.306031 (rank : 329)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	608	Target Neighborhood Hits	162	Shared Neighborhood Hits	135
SwissProt Accessions	P14770, Q14445, Q92525	Gene names	GP9
Domain Architecture
Description	Platelet glycoprotein IX precursor (GPIX) (CD42a antigen).

LRRK1_MOUSE
NC score	0.305686 (rank : 330)	θ value	5.25075e-16 (rank : 82)
Query Neighborhood Hits	608	Target Neighborhood Hits	1267	Shared Neighborhood Hits	254
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

MPP5_MOUSE
NC score	0.305219 (rank : 331)	θ value	0.000786445 (rank : 321)
Query Neighborhood Hits	608	Target Neighborhood Hits	226	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP5_HUMAN
NC score	0.305148 (rank : 332)	θ value	0.000786445 (rank : 320)
Query Neighborhood Hits	608	Target Neighborhood Hits	231	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

LRRK1_HUMAN
NC score	0.303683 (rank : 333)	θ value	3.40345e-15 (rank : 95)
Query Neighborhood Hits	608	Target Neighborhood Hits	1237	Shared Neighborhood Hits	246
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

AFAD_HUMAN
NC score	0.302973 (rank : 334)	θ value	0.00020696 (rank : 292)
Query Neighborhood Hits	608	Target Neighborhood Hits	689	Shared Neighborhood Hits	168
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

SDCB1_MOUSE
NC score	0.301746 (rank : 335)	θ value	0.000158464 (rank : 291)
Query Neighborhood Hits	608	Target Neighborhood Hits	144	Shared Neighborhood Hits	135
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

PTN13_HUMAN
NC score	0.301024 (rank : 336)	θ value	1.13037e-18 (rank : 57)
Query Neighborhood Hits	608	Target Neighborhood Hits	471	Shared Neighborhood Hits	197
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SDCB1_HUMAN
NC score	0.299897 (rank : 337)	θ value	0.000270298 (rank : 301)
Query Neighborhood Hits	608	Target Neighborhood Hits	150	Shared Neighborhood Hits	143
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

MPP3_MOUSE
NC score	0.298935 (rank : 338)	θ value	0.000786445 (rank : 319)
Query Neighborhood Hits	608	Target Neighborhood Hits	165	Shared Neighborhood Hits	134
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP3_HUMAN
NC score	0.297027 (rank : 339)	θ value	0.000786445 (rank : 318)
Query Neighborhood Hits	608	Target Neighborhood Hits	171	Shared Neighborhood Hits	134
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

GRASP_HUMAN
NC score	0.296956 (rank : 340)	θ value	0.000270298 (rank : 299)
Query Neighborhood Hits	608	Target Neighborhood Hits	147	Shared Neighborhood Hits	129
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PAR6G_HUMAN
NC score	0.296193 (rank : 341)	θ value	2.88788e-06 (rank : 254)
Query Neighborhood Hits	608	Target Neighborhood Hits	159	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

LRRK2_HUMAN
NC score	0.296003 (rank : 342)	θ value	1.24977e-17 (rank : 64)
Query Neighborhood Hits	608	Target Neighborhood Hits	1382	Shared Neighborhood Hits	255
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

PGTA_MOUSE
NC score	0.295795 (rank : 343)	θ value	0.125558 (rank : 407)
Query Neighborhood Hits	608	Target Neighborhood Hits	150	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JHK4, Q9JLX2	Gene names	Rabggta
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

PAR6B_MOUSE
NC score	0.295590 (rank : 344)	θ value	1.43324e-05 (rank : 269)
Query Neighborhood Hits	608	Target Neighborhood Hits	128	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

DVL1_HUMAN
NC score	0.295543 (rank : 345)	θ value	0.000270298 (rank : 298)
Query Neighborhood Hits	608	Target Neighborhood Hits	158	Shared Neighborhood Hits	123
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

PTN13_MOUSE
NC score	0.295338 (rank : 346)	θ value	6.85773e-16 (rank : 84)
Query Neighborhood Hits	608	Target Neighborhood Hits	426	Shared Neighborhood Hits	196
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

DVL3_MOUSE
NC score	0.295189 (rank : 347)	θ value	0.00020696 (rank : 294)
Query Neighborhood Hits	608	Target Neighborhood Hits	198	Shared Neighborhood Hits	121
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_HUMAN
NC score	0.294970 (rank : 348)	θ value	0.00020696 (rank : 293)
Query Neighborhood Hits	608	Target Neighborhood Hits	194	Shared Neighborhood Hits	118
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

PAR6B_HUMAN
NC score	0.294189 (rank : 349)	θ value	3.19293e-05 (rank : 275)
Query Neighborhood Hits	608	Target Neighborhood Hits	126	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

GRASP_MOUSE
NC score	0.293908 (rank : 350)	θ value	0.000270298 (rank : 300)
Query Neighborhood Hits	608	Target Neighborhood Hits	131	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

MPP4_MOUSE
NC score	0.293824 (rank : 351)	θ value	0.000602161 (rank : 311)
Query Neighborhood Hits	608	Target Neighborhood Hits	188	Shared Neighborhood Hits	123
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

APBA1_HUMAN
NC score	0.293546 (rank : 352)	θ value	0.000461057 (rank : 306)
Query Neighborhood Hits	608	Target Neighborhood Hits	325	Shared Neighborhood Hits	168
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

DVL1_MOUSE
NC score	0.292201 (rank : 353)	θ value	0.000461057 (rank : 307)
Query Neighborhood Hits	608	Target Neighborhood Hits	146	Shared Neighborhood Hits	117
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

PAR6G_MOUSE
NC score	0.291665 (rank : 354)	θ value	4.1701e-05 (rank : 282)
Query Neighborhood Hits	608	Target Neighborhood Hits	121	Shared Neighborhood Hits	115
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

APBA2_HUMAN
NC score	0.286713 (rank : 355)	θ value	0.000121331 (rank : 287)
Query Neighborhood Hits	608	Target Neighborhood Hits	220	Shared Neighborhood Hits	158
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
NC score	0.286511 (rank : 356)	θ value	0.000121331 (rank : 288)
Query Neighborhood Hits	608	Target Neighborhood Hits	219	Shared Neighborhood Hits	157
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

NEB1_HUMAN
NC score	0.283940 (rank : 357)	θ value	4.45536e-07 (rank : 231)
Query Neighborhood Hits	608	Target Neighborhood Hits	829	Shared Neighborhood Hits	159
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

DVL2_MOUSE
NC score	0.283789 (rank : 358)	θ value	5.44631e-05 (rank : 284)
Query Neighborhood Hits	608	Target Neighborhood Hits	233	Shared Neighborhood Hits	123
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PDLI2_HUMAN
NC score	0.283756 (rank : 359)	θ value	0.00298849 (rank : 344)
Query Neighborhood Hits	608	Target Neighborhood Hits	245	Shared Neighborhood Hits	134
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

DVL2_HUMAN
NC score	0.282809 (rank : 360)	θ value	0.000461057 (rank : 308)
Query Neighborhood Hits	608	Target Neighborhood Hits	223	Shared Neighborhood Hits	124
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PAR6A_MOUSE
NC score	0.282383 (rank : 361)	θ value	4.1701e-05 (rank : 281)
Query Neighborhood Hits	608	Target Neighborhood Hits	115	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

GP1BB_MOUSE
NC score	0.282289 (rank : 362)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	608	Target Neighborhood Hits	136	Shared Neighborhood Hits	118
SwissProt Accessions	P56400	Gene names	Gp1bb
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (CD42c antigen).

APBA3_HUMAN
NC score	0.282188 (rank : 363)	θ value	1.43324e-05 (rank : 266)
Query Neighborhood Hits	608	Target Neighborhood Hits	201	Shared Neighborhood Hits	155
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6A_HUMAN
NC score	0.281656 (rank : 364)	θ value	4.1701e-05 (rank : 280)
Query Neighborhood Hits	608	Target Neighborhood Hits	119	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

LGI2_MOUSE
NC score	0.281372 (rank : 365)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	608	Target Neighborhood Hits	200	Shared Neighborhood Hits	165
SwissProt Accessions	Q8K4Z0, Q80T76	Gene names	Lgi2, Kiaa1916
Domain Architecture
Description	Leucine-rich repeat LGI family member 2 precursor (Leucine-rich glioma-inactivated protein 2).

DVL1L_HUMAN
NC score	0.281295 (rank : 366)	θ value	0.00134147 (rank : 326)
Query Neighborhood Hits	608	Target Neighborhood Hits	146	Shared Neighborhood Hits	115
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

PDLI2_MOUSE
NC score	0.275548 (rank : 367)	θ value	3.19293e-05 (rank : 276)
Query Neighborhood Hits	608	Target Neighborhood Hits	220	Shared Neighborhood Hits	127
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PSCBP_MOUSE
NC score	0.270689 (rank : 368)	θ value	0.000461057 (rank : 310)
Query Neighborhood Hits	608	Target Neighborhood Hits	118	Shared Neighborhood Hits	113
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

EM55_HUMAN
NC score	0.269098 (rank : 369)	θ value	0.00134147 (rank : 327)
Query Neighborhood Hits	608	Target Neighborhood Hits	228	Shared Neighborhood Hits	129
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.267846 (rank : 370)	θ value	0.00134147 (rank : 328)
Query Neighborhood Hits	608	Target Neighborhood Hits	221	Shared Neighborhood Hits	126
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NEB2_HUMAN
NC score	0.267433 (rank : 371)	θ value	1.99992e-07 (rank : 223)
Query Neighborhood Hits	608	Target Neighborhood Hits	883	Shared Neighborhood Hits	150
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

GP1BB_HUMAN
NC score	0.266743 (rank : 372)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	608	Target Neighborhood Hits	125	Shared Neighborhood Hits	109
SwissProt Accessions	P13224, Q8NG40	Gene names	GP1BB
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (Antigen CD42b-beta) (CD42c antigen).

NEB2_MOUSE
NC score	0.264656 (rank : 373)	θ value	1.99992e-07 (rank : 224)
Query Neighborhood Hits	608	Target Neighborhood Hits	889	Shared Neighborhood Hits	151
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

APBA3_MOUSE
NC score	0.263346 (rank : 374)	θ value	0.00298849 (rank : 340)
Query Neighborhood Hits	608	Target Neighborhood Hits	174	Shared Neighborhood Hits	144
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

RPGF6_HUMAN
NC score	0.261461 (rank : 375)	θ value	0.00020696 (rank : 296)
Query Neighborhood Hits	608	Target Neighborhood Hits	266	Shared Neighborhood Hits	163
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SDCB2_MOUSE
NC score	0.257099 (rank : 376)	θ value	0.000270298 (rank : 302)
Query Neighborhood Hits	608	Target Neighborhood Hits	118	Shared Neighborhood Hits	112
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

FSHR_MOUSE
NC score	0.252903 (rank : 377)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	608	Target Neighborhood Hits	684	Shared Neighborhood Hits	189
SwissProt Accessions	P35378, Q9D4C2, Q9QWV8	Gene names	Fshr
Domain Architecture
Description	Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropin receptor).

SDCB2_HUMAN
NC score	0.251687 (rank : 378)	θ value	0.00390308 (rank : 352)
Query Neighborhood Hits	608	Target Neighborhood Hits	121	Shared Neighborhood Hits	118
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

STXB4_HUMAN
NC score	0.249531 (rank : 379)	θ value	0.000786445 (rank : 325)
Query Neighborhood Hits	608	Target Neighborhood Hits	616	Shared Neighborhood Hits	113
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PICK1_MOUSE
NC score	0.249423 (rank : 380)	θ value	0.62314 (rank : 454)
Query Neighborhood Hits	608	Target Neighborhood Hits	131	Shared Neighborhood Hits	122
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_HUMAN
NC score	0.248928 (rank : 381)	θ value	0.62314 (rank : 453)
Query Neighborhood Hits	608	Target Neighborhood Hits	132	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PSCBP_HUMAN
NC score	0.247848 (rank : 382)	θ value	0.00298849 (rank : 346)
Query Neighborhood Hits	608	Target Neighborhood Hits	123	Shared Neighborhood Hits	117
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

STXB4_MOUSE
NC score	0.247326 (rank : 383)	θ value	0.000602161 (rank : 314)
Query Neighborhood Hits	608	Target Neighborhood Hits	629	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYP2L_HUMAN
NC score	0.246738 (rank : 384)	θ value	0.000602161 (rank : 315)
Query Neighborhood Hits	608	Target Neighborhood Hits	400	Shared Neighborhood Hits	146
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

LRC50_HUMAN
NC score	0.241376 (rank : 385)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	608	Target Neighborhood Hits	275	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

ARHGB_HUMAN
NC score	0.233156 (rank : 386)	θ value	1.43324e-05 (rank : 267)
Query Neighborhood Hits	608	Target Neighborhood Hits	375	Shared Neighborhood Hits	175
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

RHPN1_MOUSE
NC score	0.232420 (rank : 387)	θ value	0.0330416 (rank : 386)
Query Neighborhood Hits	608	Target Neighborhood Hits	154	Shared Neighborhood Hits	134
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

ARHGC_HUMAN
NC score	0.230238 (rank : 388)	θ value	5.81887e-07 (rank : 235)
Query Neighborhood Hits	608	Target Neighborhood Hits	351	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

FSHR_HUMAN
NC score	0.229897 (rank : 389)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	608	Target Neighborhood Hits	790	Shared Neighborhood Hits	184
SwissProt Accessions	P23945, Q16225	Gene names	FSHR, LGR1
Domain Architecture
Description	Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropin receptor).

LRC50_MOUSE
NC score	0.228394 (rank : 390)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	608	Target Neighborhood Hits	190	Shared Neighborhood Hits	121
SwissProt Accessions	Q9D2H9, Q9CVS9	Gene names	Lrrc50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MPP2_MOUSE
NC score	0.226655 (rank : 391)	θ value	0.279714 (rank : 438)
Query Neighborhood Hits	608	Target Neighborhood Hits	189	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP6_MOUSE
NC score	0.226054 (rank : 392)	θ value	1.06291 (rank : 466)
Query Neighborhood Hits	608	Target Neighborhood Hits	187	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

ARHGC_MOUSE
NC score	0.226011 (rank : 393)	θ value	1.29631e-06 (rank : 247)
Query Neighborhood Hits	608	Target Neighborhood Hits	344	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LRC61_MOUSE
NC score	0.225474 (rank : 394)	θ value	0.365318 (rank : 443)
Query Neighborhood Hits	608	Target Neighborhood Hits	115	Shared Neighborhood Hits	95
SwissProt Accessions	Q8R2R5, Q3TB45, Q3UPT0	Gene names	Lrrc61
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 61.

MPP2_HUMAN
NC score	0.224765 (rank : 395)	θ value	0.279714 (rank : 437)
Query Neighborhood Hits	608	Target Neighborhood Hits	173	Shared Neighborhood Hits	97
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP6_HUMAN
NC score	0.223554 (rank : 396)	θ value	1.06291 (rank : 465)
Query Neighborhood Hits	608	Target Neighborhood Hits	180	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

LRC46_HUMAN
NC score	0.223427 (rank : 397)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	127
SwissProt Accessions	Q96FV0	Gene names	LRRC46
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 46.

RHPN1_HUMAN
NC score	0.223276 (rank : 398)	θ value	0.00228821 (rank : 336)
Query Neighborhood Hits	608	Target Neighborhood Hits	158	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RPGF2_HUMAN
NC score	0.220317 (rank : 399)	θ value	0.0148317 (rank : 373)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

TBCE_HUMAN
NC score	0.216789 (rank : 400)	θ value	1.81305 (rank : 484)
Query Neighborhood Hits	608	Target Neighborhood Hits	141	Shared Neighborhood Hits	99
SwissProt Accessions	Q15813	Gene names	TBCE
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

SHAN2_HUMAN
NC score	0.216774 (rank : 401)	θ value	0.00298849 (rank : 347)
Query Neighborhood Hits	608	Target Neighborhood Hits	346	Shared Neighborhood Hits	146
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SYNP2_MOUSE
NC score	0.214387 (rank : 402)	θ value	0.00134147 (rank : 331)
Query Neighborhood Hits	608	Target Neighborhood Hits	252	Shared Neighborhood Hits	138
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

NOS1_HUMAN
NC score	0.207334 (rank : 403)	θ value	0.000602161 (rank : 312)
Query Neighborhood Hits	608	Target Neighborhood Hits	218	Shared Neighborhood Hits	145
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SHAN2_MOUSE
NC score	0.197767 (rank : 404)	θ value	0.000786445 (rank : 324)
Query Neighborhood Hits	608	Target Neighborhood Hits	446	Shared Neighborhood Hits	147
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

RGS12_HUMAN
NC score	0.196366 (rank : 405)	θ value	0.000786445 (rank : 323)
Query Neighborhood Hits	608	Target Neighborhood Hits	333	Shared Neighborhood Hits	148
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

LRC46_MOUSE
NC score	0.194123 (rank : 406)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	608	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	Q9DAP0, Q8R1Z3	Gene names	Lrrc46
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 46.

APXL_HUMAN
NC score	0.192938 (rank : 407)	θ value	0.47712 (rank : 444)
Query Neighborhood Hits	608	Target Neighborhood Hits	553	Shared Neighborhood Hits	129
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PDLI3_HUMAN
NC score	0.191856 (rank : 408)	θ value	1.06291 (rank : 467)
Query Neighborhood Hits	608	Target Neighborhood Hits	199	Shared Neighborhood Hits	113
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI1_MOUSE
NC score	0.190302 (rank : 409)	θ value	0.00035302 (rank : 304)
Query Neighborhood Hits	608	Target Neighborhood Hits	213	Shared Neighborhood Hits	105
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

RU2A_HUMAN
NC score	0.189750 (rank : 410)	θ value	0.00228821 (rank : 337)
Query Neighborhood Hits	608	Target Neighborhood Hits	130	Shared Neighborhood Hits	98
SwissProt Accessions	P09661, Q8TBD2	Gene names	SNRPA1
Domain Architecture	No domain graphic available
Description	U2 small nuclear ribonucleoprotein A' (U2 snRNP-A').

RU2A_MOUSE
NC score	0.188603 (rank : 411)	θ value	0.00228821 (rank : 338)
Query Neighborhood Hits	608	Target Neighborhood Hits	131	Shared Neighborhood Hits	98
SwissProt Accessions	P57784, Q3U7R8, Q8K2W4, Q91YW1, Q9JKQ3	Gene names	Snrpa1
Domain Architecture	No domain graphic available
Description	U2 small nuclear ribonucleoprotein A' (U2 snRNP-A').

SYP2L_MOUSE
NC score	0.185684 (rank : 412)	θ value	0.00665767 (rank : 361)
Query Neighborhood Hits	608	Target Neighborhood Hits	289	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PDLI4_MOUSE
NC score	0.184510 (rank : 413)	θ value	0.21417 (rank : 425)
Query Neighborhood Hits	608	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI1_HUMAN
NC score	0.182622 (rank : 414)	θ value	0.000786445 (rank : 322)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	103
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

NOS1_MOUSE
NC score	0.180833 (rank : 415)	θ value	0.00390308 (rank : 349)
Query Neighborhood Hits	608	Target Neighborhood Hits	155	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PDLI4_HUMAN
NC score	0.180788 (rank : 416)	θ value	0.21417 (rank : 424)
Query Neighborhood Hits	608	Target Neighborhood Hits	245	Shared Neighborhood Hits	118
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI3_MOUSE
NC score	0.180609 (rank : 417)	θ value	0.813845 (rank : 460)
Query Neighborhood Hits	608	Target Neighborhood Hits	197	Shared Neighborhood Hits	109
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

LRC31_HUMAN
NC score	0.177850 (rank : 418)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	608	Target Neighborhood Hits	139	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

KGUA_MOUSE
NC score	0.176899 (rank : 419)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	608	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

SYNP2_HUMAN
NC score	0.176622 (rank : 420)	θ value	0.00298849 (rank : 348)
Query Neighborhood Hits	608	Target Neighborhood Hits	323	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

KGUA_HUMAN
NC score	0.175783 (rank : 421)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	608	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

TBCE_MOUSE
NC score	0.168736 (rank : 422)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	608	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CIV8	Gene names	Tbce
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone E (Tubulin-folding cofactor E).

LRC61_HUMAN
NC score	0.168417 (rank : 423)	θ value	0.279714 (rank : 436)
Query Neighborhood Hits	608	Target Neighborhood Hits	85	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BV99	Gene names	LRRC61
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 61.

RIMS1_HUMAN
NC score	0.162430 (rank : 424)	θ value	0.00509761 (rank : 358)
Query Neighborhood Hits	608	Target Neighborhood Hits	437	Shared Neighborhood Hits	140
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

AN32E_HUMAN
NC score	0.155418 (rank : 425)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	608	Target Neighborhood Hits	291	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

GIPC1_MOUSE
NC score	0.150871 (rank : 426)	θ value	0.279714 (rank : 431)
Query Neighborhood Hits	608	Target Neighborhood Hits	92	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

AN32E_MOUSE
NC score	0.149487 (rank : 427)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	608	Target Neighborhood Hits	257	Shared Neighborhood Hits	142
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

CAR12_HUMAN
NC score	0.149146 (rank : 428)	θ value	0.00509761 (rank : 357)
Query Neighborhood Hits	608	Target Neighborhood Hits	132	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

LSHR_MOUSE
NC score	0.148281 (rank : 429)	θ value	0.163984 (rank : 416)
Query Neighborhood Hits	608	Target Neighborhood Hits	686	Shared Neighborhood Hits	125
SwissProt Accessions	P30730	Gene names	Lhcgr, Lhr
Domain Architecture
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH- R) (Luteinizing hormone receptor).

PDLI5_HUMAN
NC score	0.146756 (rank : 430)	θ value	0.00134147 (rank : 330)
Query Neighborhood Hits	608	Target Neighborhood Hits	322	Shared Neighborhood Hits	123
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

LDB3_MOUSE
NC score	0.145757 (rank : 431)	θ value	0.00298849 (rank : 342)
Query Neighborhood Hits	608	Target Neighborhood Hits	510	Shared Neighborhood Hits	147
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LDB3_HUMAN
NC score	0.144421 (rank : 432)	θ value	0.00298849 (rank : 341)
Query Neighborhood Hits	608	Target Neighborhood Hits	497	Shared Neighborhood Hits	141
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

AN32A_MOUSE
NC score	0.143209 (rank : 433)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	608	Target Neighborhood Hits	254	Shared Neighborhood Hits	134
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
NC score	0.143209 (rank : 434)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	608	Target Neighborhood Hits	254	Shared Neighborhood Hits	134
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

PDLI5_MOUSE
NC score	0.142609 (rank : 435)	θ value	0.0563607 (rank : 395)
Query Neighborhood Hits	608	Target Neighborhood Hits	287	Shared Neighborhood Hits	124
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

GIPC1_HUMAN
NC score	0.142199 (rank : 436)	θ value	0.47712 (rank : 445)
Query Neighborhood Hits	608	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

PDLI7_HUMAN
NC score	0.141109 (rank : 437)	θ value	0.00390308 (rank : 350)
Query Neighborhood Hits	608	Target Neighborhood Hits	547	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SHAN1_HUMAN
NC score	0.139042 (rank : 438)	θ value	1.09739e-05 (rank : 264)
Query Neighborhood Hits	608	Target Neighborhood Hits	1041	Shared Neighborhood Hits	198
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

LRRC6_HUMAN
NC score	0.136326 (rank : 439)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	79
SwissProt Accessions	Q86X45, Q13648, Q4G183	Gene names	LRRC6, LRTP, TSLRP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

PDLI7_MOUSE
NC score	0.135381 (rank : 440)	θ value	0.00175202 (rank : 333)
Query Neighborhood Hits	608	Target Neighborhood Hits	279	Shared Neighborhood Hits	107
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LRC56_MOUSE
NC score	0.134897 (rank : 441)	θ value	3.0926 (rank : 516)
Query Neighborhood Hits	608	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K375, Q571F2	Gene names	Lrrc56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

LSHR_HUMAN
NC score	0.133459 (rank : 442)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	608	Target Neighborhood Hits	731	Shared Neighborhood Hits	122
SwissProt Accessions	P22888, Q14751, Q15996, Q9UEW9	Gene names	LHCGR, LCGR, LGR2, LHRHR
Domain Architecture
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH- R) (Luteinizing hormone receptor) (LHR).

AN32A_HUMAN
NC score	0.132511 (rank : 443)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	608	Target Neighborhood Hits	234	Shared Neighborhood Hits	124
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

RIMS2_HUMAN
NC score	0.130211 (rank : 444)	θ value	0.0431538 (rank : 392)
Query Neighborhood Hits	608	Target Neighborhood Hits	342	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

PCLO_MOUSE
NC score	0.130112 (rank : 445)	θ value	1.87187e-05 (rank : 270)
Query Neighborhood Hits	608	Target Neighborhood Hits	2275	Shared Neighborhood Hits	233
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GIPC2_HUMAN
NC score	0.130035 (rank : 446)	θ value	0.21417 (rank : 421)
Query Neighborhood Hits	608	Target Neighborhood Hits	93	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

CU002_HUMAN
NC score	0.129006 (rank : 447)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	608	Target Neighborhood Hits	84	Shared Neighborhood Hits	56
SwissProt Accessions	O43822, O14993, Q99837, Q99838	Gene names	C21orf2
Domain Architecture	No domain graphic available
Description	Protein C21orf2 (C21orf-HUMF09G8.5) (YF5/A2).

RIMS2_MOUSE
NC score	0.128566 (rank : 448)	θ value	0.0431538 (rank : 393)
Query Neighborhood Hits	608	Target Neighborhood Hits	376	Shared Neighborhood Hits	116
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

CD14_MOUSE
NC score	0.125875 (rank : 449)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	608	Target Neighborhood Hits	104	Shared Neighborhood Hits	85
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

LRC56_HUMAN
NC score	0.120130 (rank : 450)	θ value	4.03905 (rank : 537)
Query Neighborhood Hits	608	Target Neighborhood Hits	165	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

AN32B_HUMAN
NC score	0.115040 (rank : 451)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	608	Target Neighborhood Hits	243	Shared Neighborhood Hits	123
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

TSHR_MOUSE
NC score	0.115035 (rank : 452)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	608	Target Neighborhood Hits	554	Shared Neighborhood Hits	92
SwissProt Accessions	P47750, Q9D697	Gene names	Tshr
Domain Architecture
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormone receptor).

PDZD6_HUMAN
NC score	0.113338 (rank : 453)	θ value	3.0926 (rank : 519)
Query Neighborhood Hits	608	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

LRRC6_MOUSE
NC score	0.111440 (rank : 454)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	608	Target Neighborhood Hits	110	Shared Neighborhood Hits	55
SwissProt Accessions	O88978, Q9CUG2	Gene names	Lrrc6, Lrtp, Mc2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

LRC51_HUMAN
NC score	0.107700 (rank : 455)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	608	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q96E66	Gene names	LRRC51
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 51.

PRAX_MOUSE
NC score	0.105848 (rank : 456)	θ value	0.0736092 (rank : 398)
Query Neighborhood Hits	608	Target Neighborhood Hits	199	Shared Neighborhood Hits	58
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PTN4_HUMAN
NC score	0.105490 (rank : 457)	θ value	0.0252991 (rank : 379)
Query Neighborhood Hits	608	Target Neighborhood Hits	303	Shared Neighborhood Hits	124
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

TSHR_HUMAN
NC score	0.104479 (rank : 458)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	608	Target Neighborhood Hits	596	Shared Neighborhood Hits	91
SwissProt Accessions	P16473	Gene names	TSHR, LGR3
Domain Architecture
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormone receptor).

LRC25_MOUSE
NC score	0.104422 (rank : 459)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	608	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K1T1, Q3TAD5	Gene names	Lrrc25, Mapa
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 25 precursor (Monocyte and plasmacytoid-activated protein).

CEP72_HUMAN
NC score	0.104228 (rank : 460)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	608	Target Neighborhood Hits	374	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

PTN3_HUMAN
NC score	0.103712 (rank : 461)	θ value	0.21417 (rank : 426)
Query Neighborhood Hits	608	Target Neighborhood Hits	258	Shared Neighborhood Hits	118
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

LRC51_MOUSE
NC score	0.098845 (rank : 462)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	608	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DAK8, Q8R171	Gene names	Lrrc51
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 51.

LMO7_HUMAN
NC score	0.094634 (rank : 463)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	608	Target Neighborhood Hits	507	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

CEP72_MOUSE
NC score	0.094179 (rank : 464)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	608	Target Neighborhood Hits	381	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

PRAX_HUMAN
NC score	0.093938 (rank : 465)	θ value	0.0330416 (rank : 385)
Query Neighborhood Hits	608	Target Neighborhood Hits	215	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

CSKP_HUMAN
NC score	0.085641 (rank : 466)	θ value	0.00869519 (rank : 362)
Query Neighborhood Hits	608	Target Neighborhood Hits	1022	Shared Neighborhood Hits	134
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

HTRA3_MOUSE
NC score	0.083445 (rank : 467)	θ value	0.163984 (rank : 414)
Query Neighborhood Hits	608	Target Neighborhood Hits	156	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

CSKP_MOUSE
NC score	0.083335 (rank : 468)	θ value	0.00869519 (rank : 363)
Query Neighborhood Hits	608	Target Neighborhood Hits	1027	Shared Neighborhood Hits	134
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

GIPC2_MOUSE
NC score	0.081594 (rank : 469)	θ value	4.03905 (rank : 531)
Query Neighborhood Hits	608	Target Neighborhood Hits	71	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GIPC3_HUMAN
NC score	0.081159 (rank : 470)	θ value	2.36792 (rank : 494)
Query Neighborhood Hits	608	Target Neighborhood Hits	52	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

TBCEL_HUMAN
NC score	0.080658 (rank : 471)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	608	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q5QJ74	Gene names	LRRC35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

HTRA3_HUMAN
NC score	0.079349 (rank : 472)	θ value	0.279714 (rank : 432)
Query Neighborhood Hits	608	Target Neighborhood Hits	152	Shared Neighborhood Hits	69
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

GIPC3_MOUSE
NC score	0.079337 (rank : 473)	θ value	3.0926 (rank : 512)
Query Neighborhood Hits	608	Target Neighborhood Hits	53	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

TBCEL_MOUSE
NC score	0.079078 (rank : 474)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	608	Target Neighborhood Hits	85	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C5W3, Q8C7A5	Gene names	Lrrc35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

AN32D_HUMAN
NC score	0.077191 (rank : 475)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	608	Target Neighborhood Hits	95	Shared Neighborhood Hits	66
SwissProt Accessions	O95626, Q6NTC4	Gene names	ANP32D, PP32R2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2).

PDZD8_HUMAN
NC score	0.074364 (rank : 476)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	608	Target Neighborhood Hits	185	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

CD14_HUMAN
NC score	0.072558 (rank : 477)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	608	Target Neighborhood Hits	57	Shared Neighborhood Hits	51
SwissProt Accessions	P08571, Q96FR6, Q96L99, Q9UNS3	Gene names	CD14
Domain Architecture	No domain graphic available
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein) [Contains: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane- bound form].

AN32B_MOUSE
NC score	0.071852 (rank : 478)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	608	Target Neighborhood Hits	236	Shared Neighborhood Hits	96
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

NTRK3_HUMAN
NC score	0.067416 (rank : 479)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	608	Target Neighborhood Hits	1115	Shared Neighborhood Hits	180
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

CNKR2_MOUSE
NC score	0.065025 (rank : 480)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	608	Target Neighborhood Hits	197	Shared Neighborhood Hits	58
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.065006 (rank : 481)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	608	Target Neighborhood Hits	197	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

TIAM1_HUMAN
NC score	0.063747 (rank : 482)	θ value	0.21417 (rank : 428)
Query Neighborhood Hits	608	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

LRC25_HUMAN
NC score	0.057484 (rank : 483)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	608	Target Neighborhood Hits	48	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N386, Q8N9A5	Gene names	LRRC25, MAPA
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 25 precursor (Monocyte and plasmacytoid-activated protein).

HTRA1_HUMAN
NC score	0.057420 (rank : 484)	θ value	0.813845 (rank : 457)
Query Neighborhood Hits	608	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

MFA3L_HUMAN
NC score	0.056840 (rank : 485)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	608	Target Neighborhood Hits	230	Shared Neighborhood Hits	31
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

HTRA1_MOUSE
NC score	0.055947 (rank : 486)	θ value	1.06291 (rank : 464)
Query Neighborhood Hits	608	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

RNF41_MOUSE
NC score	0.055573 (rank : 487)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	608	Target Neighborhood Hits	224	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.055430 (rank : 488)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	608	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

MFA3L_MOUSE
NC score	0.054142 (rank : 489)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	608	Target Neighborhood Hits	214	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

CJ011_MOUSE
NC score	0.053610 (rank : 490)	θ value	3.0926 (rank : 508)
Query Neighborhood Hits	608	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D9B4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf11 homolog.

RGS3_HUMAN
NC score	0.052386 (rank : 491)	θ value	0.163984 (rank : 419)
Query Neighborhood Hits	608	Target Neighborhood Hits	1375	Shared Neighborhood Hits	136
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CJ011_HUMAN
NC score	0.052372 (rank : 492)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	608	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H2I8	Gene names	C10orf11
Domain Architecture	No domain graphic available
Description	Protein C10orf11.

RGS3_MOUSE
NC score	0.052334 (rank : 493)	θ value	0.62314 (rank : 455)
Query Neighborhood Hits	608	Target Neighborhood Hits	1621	Shared Neighborhood Hits	150
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHPN2_MOUSE
NC score	0.051920 (rank : 494)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	608	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

SI1L2_HUMAN
NC score	0.051828 (rank : 495)	θ value	0.0330416 (rank : 388)
Query Neighborhood Hits	608	Target Neighborhood Hits	131	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

HTRA4_HUMAN
NC score	0.051508 (rank : 496)	θ value	1.81305 (rank : 481)
Query Neighborhood Hits	608	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

TIAM1_MOUSE
NC score	0.051346 (rank : 497)	θ value	0.0193708 (rank : 375)
Query Neighborhood Hits	608	Target Neighborhood Hits	205	Shared Neighborhood Hits	53
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

HTRA2_HUMAN
NC score	0.049461 (rank : 498)	θ value	0.163984 (rank : 413)
Query Neighborhood Hits	608	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

CARD4_HUMAN
NC score	0.049271 (rank : 499)	θ value	0.0736092 (rank : 396)
Query Neighborhood Hits	608	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

SI1L2_MOUSE
NC score	0.048026 (rank : 500)	θ value	1.06291 (rank : 468)
Query Neighborhood Hits	608	Target Neighborhood Hits	124	Shared Neighborhood Hits	47
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

NXF1_MOUSE
NC score	0.045749 (rank : 501)	θ value	0.62314 (rank : 452)
Query Neighborhood Hits	608	Target Neighborhood Hits	64	Shared Neighborhood Hits	39
SwissProt Accessions	Q99JX7, O88985	Gene names	Nxf1, Tap
Domain Architecture
Description	Nuclear RNA export factor 1 (Tip-associating protein) (Tip-associated protein) (mRNA export factor TAP).

GPS2_HUMAN
NC score	0.042841 (rank : 502)	θ value	0.0431538 (rank : 391)
Query Neighborhood Hits	608	Target Neighborhood Hits	459	Shared Neighborhood Hits	30
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

MY18A_MOUSE
NC score	0.041766 (rank : 503)	θ value	0.47712 (rank : 448)
Query Neighborhood Hits	608	Target Neighborhood Hits	1989	Shared Neighborhood Hits	180
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

HTRA2_MOUSE
NC score	0.041356 (rank : 504)	θ value	2.36792 (rank : 495)
Query Neighborhood Hits	608	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

MAST4_HUMAN
NC score	0.041135 (rank : 505)	θ value	0.0193708 (rank : 374)
Query Neighborhood Hits	608	Target Neighborhood Hits	1804	Shared Neighborhood Hits	186
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SI1L1_HUMAN
NC score	0.040987 (rank : 506)	θ value	4.03905 (rank : 542)
Query Neighborhood Hits	608	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L3_HUMAN
NC score	0.040347 (rank : 507)	θ value	1.06291 (rank : 469)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	53
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SI1L1_MOUSE
NC score	0.040181 (rank : 508)	θ value	4.03905 (rank : 543)
Query Neighborhood Hits	608	Target Neighborhood Hits	189	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

MAST2_HUMAN
NC score	0.039060 (rank : 509)	θ value	0.00665767 (rank : 360)
Query Neighborhood Hits	608	Target Neighborhood Hits	1189	Shared Neighborhood Hits	151
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST1_MOUSE
NC score	0.038423 (rank : 510)	θ value	0.0252991 (rank : 378)
Query Neighborhood Hits	608	Target Neighborhood Hits	1123	Shared Neighborhood Hits	149
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST3_HUMAN
NC score	0.038004 (rank : 511)	θ value	0.0113563 (rank : 369)
Query Neighborhood Hits	608	Target Neighborhood Hits	1128	Shared Neighborhood Hits	152
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MAST2_MOUSE
NC score	0.037920 (rank : 512)	θ value	0.00869519 (rank : 365)
Query Neighborhood Hits	608	Target Neighborhood Hits	1110	Shared Neighborhood Hits	143
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MY18A_HUMAN
NC score	0.037576 (rank : 513)	θ value	0.813845 (rank : 458)
Query Neighborhood Hits	608	Target Neighborhood Hits	1929	Shared Neighborhood Hits	179
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MAST1_HUMAN
NC score	0.037413 (rank : 514)	θ value	0.0330416 (rank : 384)
Query Neighborhood Hits	608	Target Neighborhood Hits	1146	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SRRM2_MOUSE
NC score	0.035882 (rank : 515)	θ value	0.813845 (rank : 461)
Query Neighborhood Hits	608	Target Neighborhood Hits	1470	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NAL12_HUMAN
NC score	0.034597 (rank : 516)	θ value	0.62314 (rank : 451)
Query Neighborhood Hits	608	Target Neighborhood Hits	96	Shared Neighborhood Hits	32
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

SRRM1_MOUSE
NC score	0.033830 (rank : 517)	θ value	4.03905 (rank : 546)
Query Neighborhood Hits	608	Target Neighborhood Hits	966	Shared Neighborhood Hits	90
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BAT2_HUMAN
NC score	0.032591 (rank : 518)	θ value	4.03905 (rank : 525)
Query Neighborhood Hits	608	Target Neighborhood Hits	931	Shared Neighborhood Hits	106
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SYNPO_MOUSE
NC score	0.031306 (rank : 519)	θ value	0.813845 (rank : 462)
Query Neighborhood Hits	608	Target Neighborhood Hits	242	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

CLC4M_HUMAN
NC score	0.030261 (rank : 520)	θ value	0.0431538 (rank : 390)
Query Neighborhood Hits	608	Target Neighborhood Hits	291	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

RP1L1_HUMAN
NC score	0.026664 (rank : 521)	θ value	0.0736092 (rank : 399)
Query Neighborhood Hits	608	Target Neighborhood Hits	1072	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

OGFR_HUMAN
NC score	0.026256 (rank : 522)	θ value	0.0113563 (rank : 370)
Query Neighborhood Hits	608	Target Neighborhood Hits	1582	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CP053_HUMAN
NC score	0.024536 (rank : 523)	θ value	0.163984 (rank : 412)
Query Neighborhood Hits	608	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

TM108_MOUSE
NC score	0.023758 (rank : 524)	θ value	0.21417 (rank : 429)
Query Neighborhood Hits	608	Target Neighborhood Hits	336	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

NFH_MOUSE
NC score	0.022910 (rank : 525)	θ value	8.97725e-08 (rank : 208)
Query Neighborhood Hits	608	Target Neighborhood Hits	2247	Shared Neighborhood Hits	131
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRRT3_HUMAN
NC score	0.022691 (rank : 526)	θ value	0.125558 (rank : 408)
Query Neighborhood Hits	608	Target Neighborhood Hits	998	Shared Neighborhood Hits	78
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SIPA1_MOUSE
NC score	0.022688 (rank : 527)	θ value	4.03905 (rank : 544)
Query Neighborhood Hits	608	Target Neighborhood Hits	158	Shared Neighborhood Hits	27
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

BSN_MOUSE
NC score	0.022472 (rank : 528)	θ value	6.88961 (rank : 568)
Query Neighborhood Hits	608	Target Neighborhood Hits	2057	Shared Neighborhood Hits	135
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

LIMK2_MOUSE
NC score	0.021969 (rank : 529)	θ value	0.000786445 (rank : 317)
Query Neighborhood Hits	608	Target Neighborhood Hits	998	Shared Neighborhood Hits	81
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

ZN750_MOUSE
NC score	0.021311 (rank : 530)	θ value	1.38821 (rank : 478)
Query Neighborhood Hits	608	Target Neighborhood Hits	346	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

LIMK1_HUMAN
NC score	0.020754 (rank : 531)	θ value	0.279714 (rank : 434)
Query Neighborhood Hits	608	Target Neighborhood Hits	1005	Shared Neighborhood Hits	92
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

NCOR2_HUMAN
NC score	0.020494 (rank : 532)	θ value	3.0926 (rank : 518)
Query Neighborhood Hits	608	Target Neighborhood Hits	870	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

LIMK2_HUMAN
NC score	0.020340 (rank : 533)	θ value	0.00134147 (rank : 329)
Query Neighborhood Hits	608	Target Neighborhood Hits	986	Shared Neighborhood Hits	84
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

SRCA_MOUSE
NC score	0.020060 (rank : 534)	θ value	0.0252991 (rank : 380)
Query Neighborhood Hits	608	Target Neighborhood Hits	212	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

PSMF1_MOUSE
NC score	0.019780 (rank : 535)	θ value	0.125558 (rank : 409)
Query Neighborhood Hits	608	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

GORS2_HUMAN
NC score	0.019517 (rank : 536)	θ value	4.03905 (rank : 532)
Query Neighborhood Hits	608	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H8Y8, Q96I74, Q96K84, Q9H946, Q9UFW4	Gene names	GORASP2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) (Golgi phosphoprotein 6) (GOLPH6).

MTSS1_MOUSE
NC score	0.019228 (rank : 537)	θ value	0.47712 (rank : 447)
Query Neighborhood Hits	608	Target Neighborhood Hits	592	Shared Neighborhood Hits	49
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

LAD1_HUMAN
NC score	0.018955 (rank : 538)	θ value	6.88961 (rank : 575)
Query Neighborhood Hits	608	Target Neighborhood Hits	441	Shared Neighborhood Hits	42
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SPEG_MOUSE
NC score	0.018712 (rank : 539)	θ value	5.27518 (rank : 563)
Query Neighborhood Hits	608	Target Neighborhood Hits	1959	Shared Neighborhood Hits	129
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TARA_HUMAN
NC score	0.018674 (rank : 540)	θ value	1.38821 (rank : 477)
Query Neighborhood Hits	608	Target Neighborhood Hits	1626	Shared Neighborhood Hits	110
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LIMK1_MOUSE
NC score	0.018472 (rank : 541)	θ value	1.38821 (rank : 472)
Query Neighborhood Hits	608	Target Neighborhood Hits	1008	Shared Neighborhood Hits	91
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

CT172_HUMAN
NC score	0.018429 (rank : 542)	θ value	2.36792 (rank : 490)
Query Neighborhood Hits	608	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H410, Q5JW56, Q9H8P4	Gene names	C20orf172
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172.

LPP_HUMAN
NC score	0.017890 (rank : 543)	θ value	8.99809 (rank : 594)
Query Neighborhood Hits	608	Target Neighborhood Hits	775	Shared Neighborhood Hits	69
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

K0256_MOUSE
NC score	0.017511 (rank : 544)	θ value	0.0961366 (rank : 401)
Query Neighborhood Hits	608	Target Neighborhood Hits	121	Shared Neighborhood Hits	17
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

TJAP1_MOUSE
NC score	0.017419 (rank : 545)	θ value	0.125558 (rank : 411)
Query Neighborhood Hits	608	Target Neighborhood Hits	295	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

MLL2_HUMAN
NC score	0.017416 (rank : 546)	θ value	2.36792 (rank : 500)
Query Neighborhood Hits	608	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BTBD7_HUMAN
NC score	0.017327 (rank : 547)	θ value	0.0330416 (rank : 382)
Query Neighborhood Hits	608	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

K1688_MOUSE
NC score	0.017316 (rank : 548)	θ value	0.21417 (rank : 422)
Query Neighborhood Hits	608	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

PELP1_MOUSE
NC score	0.017289 (rank : 549)	θ value	3.0926 (rank : 520)
Query Neighborhood Hits	608	Target Neighborhood Hits	709	Shared Neighborhood Hits	67
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

ATX2L_HUMAN
NC score	0.017013 (rank : 550)	θ value	5.27518 (rank : 549)
Query Neighborhood Hits	608	Target Neighborhood Hits	443	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

K1688_HUMAN
NC score	0.016653 (rank : 551)	θ value	1.81305 (rank : 482)
Query Neighborhood Hits	608	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CIC_HUMAN
NC score	0.016242 (rank : 552)	θ value	0.62314 (rank : 449)
Query Neighborhood Hits	608	Target Neighborhood Hits	992	Shared Neighborhood Hits	96
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

K0157_HUMAN
NC score	0.015782 (rank : 553)	θ value	0.365318 (rank : 441)
Query Neighborhood Hits	608	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q15018, Q96H11	Gene names	KIAA0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

RGNEF_MOUSE
NC score	0.015237 (rank : 554)	θ value	5.27518 (rank : 562)
Query Neighborhood Hits	608	Target Neighborhood Hits	641	Shared Neighborhood Hits	31
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

OGFR_MOUSE
NC score	0.015137 (rank : 555)	θ value	8.99809 (rank : 600)
Query Neighborhood Hits	608	Target Neighborhood Hits	584	Shared Neighborhood Hits	49
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PRAM8_HUMAN
NC score	0.014946 (rank : 556)	θ value	0.0961366 (rank : 405)
Query Neighborhood Hits	608	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VWM4	Gene names	PRAMEF8
Domain Architecture	No domain graphic available
Description	PRAME family member 8.

PRAM7_HUMAN
NC score	0.014882 (rank : 557)	θ value	0.0961366 (rank : 404)
Query Neighborhood Hits	608	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VXH5	Gene names	PRAMEF7
Domain Architecture	No domain graphic available
Description	PRAME family member 7.

GORS2_MOUSE
NC score	0.014624 (rank : 558)	θ value	4.03905 (rank : 533)
Query Neighborhood Hits	608	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

DPOG1_HUMAN
NC score	0.014451 (rank : 559)	θ value	2.36792 (rank : 491)
Query Neighborhood Hits	608	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P54098, Q8NFM2, Q92515	Gene names	POLG, MDP1, POLG1, POLGA
Domain Architecture
Description	DNA polymerase subunit gamma 1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha).

RUSC2_MOUSE
NC score	0.014306 (rank : 560)	θ value	3.0926 (rank : 521)
Query Neighborhood Hits	608	Target Neighborhood Hits	305	Shared Neighborhood Hits	36
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

MTSS1_HUMAN
NC score	0.014243 (rank : 561)	θ value	3.0926 (rank : 517)
Query Neighborhood Hits	608	Target Neighborhood Hits	504	Shared Neighborhood Hits	41
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CIAS1_MOUSE
NC score	0.013429 (rank : 562)	θ value	5.27518 (rank : 551)
Query Neighborhood Hits	608	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

CGRE1_HUMAN
NC score	0.013283 (rank : 563)	θ value	4.03905 (rank : 527)
Query Neighborhood Hits	608	Target Neighborhood Hits	354	Shared Neighborhood Hits	28
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

MAP1A_HUMAN
NC score	0.013019 (rank : 564)	θ value	8.99809 (rank : 596)
Query Neighborhood Hits	608	Target Neighborhood Hits	1626	Shared Neighborhood Hits	97
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SAPS1_HUMAN
NC score	0.012788 (rank : 565)	θ value	4.03905 (rank : 541)
Query Neighborhood Hits	608	Target Neighborhood Hits	704	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MAGE1_HUMAN
NC score	0.012747 (rank : 566)	θ value	1.38821 (rank : 474)
Query Neighborhood Hits	608	Target Neighborhood Hits	1389	Shared Neighborhood Hits	96
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RIMB1_HUMAN
NC score	0.012738 (rank : 567)	θ value	1.38821 (rank : 475)
Query Neighborhood Hits	608	Target Neighborhood Hits	1479	Shared Neighborhood Hits	89
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TXLNB_HUMAN
NC score	0.012682 (rank : 568)	θ value	2.36792 (rank : 505)
Query Neighborhood Hits	608	Target Neighborhood Hits	912	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

CBL_MOUSE
NC score	0.012358 (rank : 569)	θ value	6.88961 (rank : 569)
Query Neighborhood Hits	608	Target Neighborhood Hits	426	Shared Neighborhood Hits	35
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

SMOO_HUMAN
NC score	0.011881 (rank : 570)	θ value	4.03905 (rank : 545)
Query Neighborhood Hits	608	Target Neighborhood Hits	391	Shared Neighborhood Hits	49
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

ZMYM3_HUMAN
NC score	0.011868 (rank : 571)	θ value	2.36792 (rank : 506)
Query Neighborhood Hits	608	Target Neighborhood Hits	223	Shared Neighborhood Hits	34
SwissProt Accessions	Q14202, O15089	Gene names	ZMYM3, DXS6673E, KIAA0385, ZNF261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261).

PHLB1_MOUSE
NC score	0.011440 (rank : 572)	θ value	5.27518 (rank : 561)
Query Neighborhood Hits	608	Target Neighborhood Hits	678	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TEX2_MOUSE
NC score	0.011188 (rank : 573)	θ value	1.81305 (rank : 485)
Query Neighborhood Hits	608	Target Neighborhood Hits	121	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

SEPT9_HUMAN
NC score	0.010928 (rank : 574)	θ value	0.125558 (rank : 410)
Query Neighborhood Hits	608	Target Neighborhood Hits	706	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

FAAA_MOUSE
NC score	0.010733 (rank : 575)	θ value	2.36792 (rank : 492)
Query Neighborhood Hits	608	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P35505	Gene names	Fah
Domain Architecture
Description	Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA).

RC3H1_HUMAN
NC score	0.010390 (rank : 576)	θ value	8.99809 (rank : 602)
Query Neighborhood Hits	608	Target Neighborhood Hits	433	Shared Neighborhood Hits	32
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

ADCY4_MOUSE
NC score	0.010231 (rank : 577)	θ value	0.0563607 (rank : 394)
Query Neighborhood Hits	608	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WF3	Gene names	Adcy4
Domain Architecture
Description	Adenylate cyclase type 4 (EC 4.6.1.1) (Adenylate cyclase type IV) (ATP pyrophosphate-lyase 4) (Adenylyl cyclase 4).

PININ_HUMAN
NC score	0.010042 (rank : 578)	θ value	6.88961 (rank : 579)
Query Neighborhood Hits	608	Target Neighborhood Hits	753	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SPR1A_MOUSE
NC score	0.009950 (rank : 579)	θ value	6.88961 (rank : 582)
Query Neighborhood Hits	608	Target Neighborhood Hits	343	Shared Neighborhood Hits	28
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TBCD2_HUMAN
NC score	0.009872 (rank : 580)	θ value	0.21417 (rank : 427)
Query Neighborhood Hits	608	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

K0319_HUMAN
NC score	0.009837 (rank : 581)	θ value	5.27518 (rank : 557)
Query Neighborhood Hits	608	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

MEGF8_HUMAN
NC score	0.009790 (rank : 582)	θ value	0.0961366 (rank : 403)
Query Neighborhood Hits	608	Target Neighborhood Hits	528	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CGRE1_MOUSE
NC score	0.009678 (rank : 583)	θ value	6.88961 (rank : 570)
Query Neighborhood Hits	608	Target Neighborhood Hits	173	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

BAT3_HUMAN
NC score	0.009449 (rank : 584)	θ value	4.03905 (rank : 526)
Query Neighborhood Hits	608	Target Neighborhood Hits	490	Shared Neighborhood Hits	41
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

HNRPK_HUMAN
NC score	0.009414 (rank : 585)	θ value	1.81305 (rank : 479)
Query Neighborhood Hits	608	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
NC score	0.009414 (rank : 586)	θ value	1.81305 (rank : 480)
Query Neighborhood Hits	608	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

FHOD1_HUMAN
NC score	0.009274 (rank : 587)	θ value	2.36792 (rank : 493)
Query Neighborhood Hits	608	Target Neighborhood Hits	184	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

CO039_MOUSE
NC score	0.009215 (rank : 588)	θ value	8.99809 (rank : 588)
Query Neighborhood Hits	608	Target Neighborhood Hits	445	Shared Neighborhood Hits	39
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

NSBP1_MOUSE
NC score	0.008932 (rank : 589)	θ value	0.813845 (rank : 459)
Query Neighborhood Hits	608	Target Neighborhood Hits	681	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

SMCE1_MOUSE
NC score	0.008888 (rank : 590)	θ value	1.38821 (rank : 476)
Query Neighborhood Hits	608	Target Neighborhood Hits	409	Shared Neighborhood Hits	24
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

LRP3_HUMAN
NC score	0.008883 (rank : 591)	θ value	0.21417 (rank : 423)
Query Neighborhood Hits	608	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

DCP1A_HUMAN
NC score	0.008882 (rank : 592)	θ value	3.0926 (rank : 509)
Query Neighborhood Hits	608	Target Neighborhood Hits	228	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

MINT_HUMAN
NC score	0.008777 (rank : 593)	θ value	4.03905 (rank : 538)
Query Neighborhood Hits	608	Target Neighborhood Hits	1291	Shared Neighborhood Hits	91
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

BRD8_MOUSE
NC score	0.008646 (rank : 594)	θ value	3.0926 (rank : 507)
Query Neighborhood Hits	608	Target Neighborhood Hits	422	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

EFS_MOUSE
NC score	0.008614 (rank : 595)	θ value	5.27518 (rank : 553)
Query Neighborhood Hits	608	Target Neighborhood Hits	389	Shared Neighborhood Hits	42
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

MDN1_HUMAN
NC score	0.008425 (rank : 596)	θ value	5.27518 (rank : 558)
Query Neighborhood Hits	608	Target Neighborhood Hits	662	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NRAP_HUMAN
NC score	0.008390 (rank : 597)	θ value	4.03905 (rank : 539)
Query Neighborhood Hits	608	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

LEO1_HUMAN
NC score	0.008175 (rank : 598)	θ value	2.36792 (rank : 499)
Query Neighborhood Hits	608	Target Neighborhood Hits	958	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CAC1G_HUMAN
NC score	0.008100 (rank : 599)	θ value	2.36792 (rank : 488)
Query Neighborhood Hits	608	Target Neighborhood Hits	587	Shared Neighborhood Hits	48
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

TCAL5_HUMAN
NC score	0.007754 (rank : 600)	θ value	2.36792 (rank : 504)
Query Neighborhood Hits	608	Target Neighborhood Hits	806	Shared Neighborhood Hits	46
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

BSCL2_MOUSE
NC score	0.007681 (rank : 601)	θ value	5.27518 (rank : 550)
Query Neighborhood Hits	608	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

MAML2_HUMAN
NC score	0.007356 (rank : 602)	θ value	8.99809 (rank : 595)
Query Neighborhood Hits	608	Target Neighborhood Hits	360	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

BRE1B_HUMAN
NC score	0.007308 (rank : 603)	θ value	0.365318 (rank : 439)
Query Neighborhood Hits	608	Target Neighborhood Hits	1040	Shared Neighborhood Hits	47
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

UBP10_MOUSE
NC score	0.007232 (rank : 604)	θ value	4.03905 (rank : 547)
Query Neighborhood Hits	608	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

CAC1H_HUMAN
NC score	0.007229 (rank : 605)	θ value	0.813845 (rank : 456)
Query Neighborhood Hits	608	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

PININ_MOUSE
NC score	0.006859 (rank : 606)	θ value	6.88961 (rank : 580)
Query Neighborhood Hits	608	Target Neighborhood Hits	777	Shared Neighborhood Hits	57
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

CI152_HUMAN
NC score	0.006858 (rank : 607)	θ value	8.99809 (rank : 587)
Query Neighborhood Hits	608	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JTZ5	Gene names	C9orf152
Domain Architecture	No domain graphic available
Description	Protein C9orf152.

RIMB1_MOUSE
NC score	0.006830 (rank : 608)	θ value	8.99809 (rank : 603)
Query Neighborhood Hits	608	Target Neighborhood Hits	1376	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PGRP2_HUMAN
NC score	0.006643 (rank : 609)	θ value	8.99809 (rank : 601)
Query Neighborhood Hits	608	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PD5, Q96N74, Q9UC60	Gene names	PGLYRP2, PGLYRPL, PGRPL
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2).

PALB2_HUMAN
NC score	0.006616 (rank : 610)	θ value	5.27518 (rank : 559)
Query Neighborhood Hits	608	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

DSRAD_MOUSE
NC score	0.006539 (rank : 611)	θ value	4.03905 (rank : 529)
Query Neighborhood Hits	608	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

FBLN2_MOUSE
NC score	0.006491 (rank : 612)	θ value	1.38821 (rank : 470)
Query Neighborhood Hits	608	Target Neighborhood Hits	505	Shared Neighborhood Hits	30
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

DAB2_MOUSE
NC score	0.006421 (rank : 613)	θ value	6.88961 (rank : 572)
Query Neighborhood Hits	608	Target Neighborhood Hits	163	Shared Neighborhood Hits	12
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

ERIC1_HUMAN
NC score	0.006301 (rank : 614)	θ value	5.27518 (rank : 554)
Query Neighborhood Hits	608	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

MAP1B_MOUSE
NC score	0.006133 (rank : 615)	θ value	8.99809 (rank : 597)
Query Neighborhood Hits	608	Target Neighborhood Hits	977	Shared Neighborhood Hits	67
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

INVS_MOUSE
NC score	0.005856 (rank : 616)	θ value	0.00869519 (rank : 364)
Query Neighborhood Hits	608	Target Neighborhood Hits	609	Shared Neighborhood Hits	40
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

HUWE1_MOUSE
NC score	0.005716 (rank : 617)	θ value	2.36792 (rank : 496)
Query Neighborhood Hits	608	Target Neighborhood Hits	406	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

EVPL_HUMAN
NC score	0.005614 (rank : 618)	θ value	0.279714 (rank : 430)
Query Neighborhood Hits	608	Target Neighborhood Hits	895	Shared Neighborhood Hits	39
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

SYMPK_MOUSE
NC score	0.005568 (rank : 619)	θ value	6.88961 (rank : 584)
Query Neighborhood Hits	608	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

IRX2_HUMAN
NC score	0.005388 (rank : 620)	θ value	0.47712 (rank : 446)
Query Neighborhood Hits	608	Target Neighborhood Hits	358	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

ADCY4_HUMAN
NC score	0.005024 (rank : 621)	θ value	6.88961 (rank : 566)
Query Neighborhood Hits	608	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFM4, Q96ML7	Gene names	ADCY4
Domain Architecture
Description	Adenylate cyclase type 4 (EC 4.6.1.1) (Adenylate cyclase type IV) (ATP pyrophosphate-lyase 4) (Adenylyl cyclase 4).

GEMI5_MOUSE
NC score	0.004959 (rank : 622)	θ value	0.21417 (rank : 420)
Query Neighborhood Hits	608	Target Neighborhood Hits	424	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

GNAS1_MOUSE
NC score	0.004852 (rank : 623)	θ value	5.27518 (rank : 556)
Query Neighborhood Hits	608	Target Neighborhood Hits	651	Shared Neighborhood Hits	53
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

PNMA2_HUMAN
NC score	0.004791 (rank : 624)	θ value	2.36792 (rank : 501)
Query Neighborhood Hits	608	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UL42, O94959, O95145, Q9UL43	Gene names	PNMA2, KIAA0883, MA2
Domain Architecture
Description	Paraneoplastic antigen Ma2 (Onconeuronal antigen MA2) (Paraneoplastic neuronal antigen MM2) (40 kDa neuronal protein).

SOX30_MOUSE
NC score	0.004753 (rank : 625)	θ value	2.36792 (rank : 503)
Query Neighborhood Hits	608	Target Neighborhood Hits	374	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

JADE2_MOUSE
NC score	0.004473 (rank : 626)	θ value	2.36792 (rank : 497)
Query Neighborhood Hits	608	Target Neighborhood Hits	560	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

F10A1_HUMAN
NC score	0.004174 (rank : 627)	θ value	4.03905 (rank : 530)
Query Neighborhood Hits	608	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

F10A5_HUMAN
NC score	0.003945 (rank : 628)	θ value	5.27518 (rank : 555)
Query Neighborhood Hits	608	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

DIAP3_MOUSE
NC score	0.003893 (rank : 629)	θ value	3.0926 (rank : 510)
Query Neighborhood Hits	608	Target Neighborhood Hits	221	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

ZN385_HUMAN
NC score	0.003636 (rank : 630)	θ value	8.99809 (rank : 607)
Query Neighborhood Hits	608	Target Neighborhood Hits	614	Shared Neighborhood Hits	40
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

K1802_MOUSE
NC score	0.003432 (rank : 631)	θ value	1.38821 (rank : 471)
Query Neighborhood Hits	608	Target Neighborhood Hits	1596	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

STAT2_MOUSE
NC score	0.003250 (rank : 632)	θ value	3.0926 (rank : 523)
Query Neighborhood Hits	608	Target Neighborhood Hits	175	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SPHK2_HUMAN
NC score	0.003141 (rank : 633)	θ value	8.99809 (rank : 604)
Query Neighborhood Hits	608	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

GGA1_HUMAN
NC score	0.002885 (rank : 634)	θ value	6.88961 (rank : 574)
Query Neighborhood Hits	608	Target Neighborhood Hits	169	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

DOCK8_MOUSE
NC score	0.002800 (rank : 635)	θ value	5.27518 (rank : 552)
Query Neighborhood Hits	608	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

ANR25_MOUSE
NC score	0.002510 (rank : 636)	θ value	2.36792 (rank : 487)
Query Neighborhood Hits	608	Target Neighborhood Hits	398	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

PARPT_MOUSE
NC score	0.002482 (rank : 637)	θ value	5.27518 (rank : 560)
Query Neighborhood Hits	608	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

CO5A2_HUMAN
NC score	0.002326 (rank : 638)	θ value	4.03905 (rank : 528)
Query Neighborhood Hits	608	Target Neighborhood Hits	760	Shared Neighborhood Hits	53
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

DEAF1_MOUSE
NC score	0.002248 (rank : 639)	θ value	8.99809 (rank : 589)
Query Neighborhood Hits	608	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

MYST3_MOUSE
NC score	0.002161 (rank : 640)	θ value	8.99809 (rank : 599)
Query Neighborhood Hits	608	Target Neighborhood Hits	688	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

CROCC_MOUSE
NC score	0.002148 (rank : 641)	θ value	2.36792 (rank : 489)
Query Neighborhood Hits	608	Target Neighborhood Hits	1460	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DOCK8_HUMAN
NC score	0.002113 (rank : 642)	θ value	8.99809 (rank : 591)
Query Neighborhood Hits	608	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

ANR11_HUMAN
NC score	0.001981 (rank : 643)	θ value	5.27518 (rank : 548)
Query Neighborhood Hits	608	Target Neighborhood Hits	1289	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ATG4D_HUMAN
NC score	0.001946 (rank : 644)	θ value	6.88961 (rank : 567)
Query Neighborhood Hits	608	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TL0	Gene names	ATG4D, APG4D, AUTL4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).

EPN2_MOUSE
NC score	0.001717 (rank : 645)	θ value	8.99809 (rank : 592)
Query Neighborhood Hits	608	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

HGS_HUMAN
NC score	0.001551 (rank : 646)	θ value	3.0926 (rank : 514)
Query Neighborhood Hits	608	Target Neighborhood Hits	517	Shared Neighborhood Hits	33
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

REPS1_MOUSE
NC score	0.001216 (rank : 647)	θ value	6.88961 (rank : 581)
Query Neighborhood Hits	608	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

MCM2_MOUSE
NC score	0.001091 (rank : 648)	θ value	8.99809 (rank : 598)
Query Neighborhood Hits	608	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P97310, O08971, O89057, Q8C2R0	Gene names	Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

SEC63_MOUSE
NC score	0.000866 (rank : 649)	θ value	1.81305 (rank : 483)
Query Neighborhood Hits	608	Target Neighborhood Hits	601	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

EPHB6_MOUSE
NC score	0.000834 (rank : 650)	θ value	0.125558 (rank : 406)
Query Neighborhood Hits	608	Target Neighborhood Hits	906	Shared Neighborhood Hits	33
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

SEC63_HUMAN
NC score	0.000552 (rank : 651)	θ value	3.0926 (rank : 522)
Query Neighborhood Hits	608	Target Neighborhood Hits	586	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

EPHB6_HUMAN
NC score	-0.000067 (rank : 652)	θ value	0.365318 (rank : 440)
Query Neighborhood Hits	608	Target Neighborhood Hits	912	Shared Neighborhood Hits	30
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EHMT2_MOUSE
NC score	-0.000519 (rank : 653)	θ value	3.0926 (rank : 511)
Query Neighborhood Hits	608	Target Neighborhood Hits	750	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

DJC12_HUMAN
NC score	-0.001117 (rank : 654)	θ value	8.99809 (rank : 590)
Query Neighborhood Hits	608	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKB3, Q9UKB2	Gene names	DNAJC12, JDP1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

RRBP1_MOUSE
NC score	-0.001306 (rank : 655)	θ value	2.36792 (rank : 502)
Query Neighborhood Hits	608	Target Neighborhood Hits	1650	Shared Neighborhood Hits	64
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

UBP2_HUMAN
NC score	-0.001406 (rank : 656)	θ value	6.88961 (rank : 586)
Query Neighborhood Hits	608	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

TLE1_HUMAN
NC score	-0.001599 (rank : 657)	θ value	3.0926 (rank : 524)
Query Neighborhood Hits	608	Target Neighborhood Hits	485	Shared Neighborhood Hits	18
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

RBM28_HUMAN
NC score	-0.002126 (rank : 658)	θ value	4.03905 (rank : 540)
Query Neighborhood Hits	608	Target Neighborhood Hits	307	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NW13, Q96CV3	Gene names	RBM28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

SSPO_MOUSE
NC score	-0.002325 (rank : 659)	θ value	6.88961 (rank : 583)
Query Neighborhood Hits	608	Target Neighborhood Hits	800	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

COKA1_HUMAN
NC score	-0.002598 (rank : 660)	θ value	6.88961 (rank : 571)
Query Neighborhood Hits	608	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

LIRB3_HUMAN
NC score	-0.002634 (rank : 661)	θ value	8.99809 (rank : 593)
Query Neighborhood Hits	608	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

ADA30_HUMAN
NC score	-0.003268 (rank : 662)	θ value	6.88961 (rank : 565)
Query Neighborhood Hits	608	Target Neighborhood Hits	391	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

LATS1_MOUSE
NC score	-0.003350 (rank : 663)	θ value	2.36792 (rank : 498)
Query Neighborhood Hits	608	Target Neighborhood Hits	1027	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

GP152_MOUSE
NC score	-0.003537 (rank : 664)	θ value	3.0926 (rank : 513)
Query Neighborhood Hits	608	Target Neighborhood Hits	607	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

PAK4_MOUSE
NC score	-0.003600 (rank : 665)	θ value	6.88961 (rank : 578)
Query Neighborhood Hits	608	Target Neighborhood Hits	1098	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

KI21A_MOUSE
NC score	-0.005633 (rank : 666)	θ value	4.03905 (rank : 534)
Query Neighborhood Hits	608	Target Neighborhood Hits	1317	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

FOG1_MOUSE
NC score	-0.007047 (rank : 667)	θ value	6.88961 (rank : 573)
Query Neighborhood Hits	608	Target Neighborhood Hits	1237	Shared Neighborhood Hits	60
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

TRYG1_MOUSE
NC score	-0.007612 (rank : 668)	θ value	5.27518 (rank : 564)
Query Neighborhood Hits	608	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

WD51A_HUMAN
NC score	-0.008804 (rank : 669)	θ value	8.99809 (rank : 605)
Query Neighborhood Hits	608	Target Neighborhood Hits	337	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NBT0, Q2TAK6, Q96IK6, Q9UFJ8	Gene names	WDR51A
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

GLI3_HUMAN
NC score	-0.009791 (rank : 670)	θ value	0.0252991 (rank : 377)
Query Neighborhood Hits	608	Target Neighborhood Hits	871	Shared Neighborhood Hits	25
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

ZEP1_MOUSE
NC score	-0.010656 (rank : 671)	θ value	8.99809 (rank : 606)
Query Neighborhood Hits	608	Target Neighborhood Hits	1063	Shared Neighborhood Hits	50
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZNF8_HUMAN
NC score	-0.012473 (rank : 672)	θ value	0.00390308 (rank : 356)
Query Neighborhood Hits	608	Target Neighborhood Hits	748	Shared Neighborhood Hits	11
SwissProt Accessions	P17098, Q6PI99	Gene names	ZNF8
Domain Architecture	No domain graphic available
Description	Zinc finger protein 8 (Zinc finger protein HF.18).

ZSCA5_HUMAN
NC score	-0.014160 (rank : 673)	θ value	1.81305 (rank : 486)
Query Neighborhood Hits	608	Target Neighborhood Hits	862	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

ZN394_HUMAN
NC score	-0.015148 (rank : 674)	θ value	8.99809 (rank : 608)
Query Neighborhood Hits	608	Target Neighborhood Hits	752	Shared Neighborhood Hits	14
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.