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Network neighborhood for query Sequence : SI1L3_HUMAN

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SI1L3_HUMAN
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SI1L1_HUMAN
θ value	0 (rank : 1)	NC score	0.954631 (rank : 4)
Query Neighborhood Hits	305	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
θ value	0 (rank : 2)	NC score	0.952997 (rank : 5)
Query Neighborhood Hits	305	Target Neighborhood Hits	189	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L2_HUMAN
θ value	0 (rank : 3)	NC score	0.956940 (rank : 3)
Query Neighborhood Hits	305	Target Neighborhood Hits	131	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	0 (rank : 4)	NC score	0.957882 (rank : 2)
Query Neighborhood Hits	305	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	305	Target Neighborhood Hits	305	Shared Neighborhood Hits	305
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SIPA1_HUMAN
θ value	5.18743e-173 (rank : 6)	NC score	0.917505 (rank : 7)
Query Neighborhood Hits	305	Target Neighborhood Hits	250	Shared Neighborhood Hits	55
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SIPA1_MOUSE
θ value	7.25522e-167 (rank : 7)	NC score	0.925413 (rank : 6)
Query Neighborhood Hits	305	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

RGP2_HUMAN
θ value	1.45929e-58 (rank : 8)	NC score	0.874658 (rank : 8)
Query Neighborhood Hits	305	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

GRIPE_HUMAN
θ value	2.0648e-12 (rank : 9)	NC score	0.453460 (rank : 9)
Query Neighborhood Hits	305	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
θ value	1.74796e-11 (rank : 10)	NC score	0.441591 (rank : 10)
Query Neighborhood Hits	305	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
θ value	7.34386e-10 (rank : 11)	NC score	0.431781 (rank : 11)
Query Neighborhood Hits	305	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
θ value	2.13673e-09 (rank : 12)	NC score	0.411422 (rank : 12)
Query Neighborhood Hits	305	Target Neighborhood Hits	48	Shared Neighborhood Hits	15
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

WIRE_MOUSE
θ value	0.00020696 (rank : 13)	NC score	0.109357 (rank : 21)
Query Neighborhood Hits	305	Target Neighborhood Hits	310	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WIRE_HUMAN
θ value	0.00035302 (rank : 14)	NC score	0.107472 (rank : 22)
Query Neighborhood Hits	305	Target Neighborhood Hits	329	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

SHAN1_HUMAN
θ value	0.000461057 (rank : 15)	NC score	0.109886 (rank : 20)
Query Neighborhood Hits	305	Target Neighborhood Hits	1041	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

CBP_HUMAN
θ value	0.00102713 (rank : 16)	NC score	0.072836 (rank : 37)
Query Neighborhood Hits	305	Target Neighborhood Hits	941	Shared Neighborhood Hits	103
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SHAN2_HUMAN
θ value	0.00665767 (rank : 17)	NC score	0.154358 (rank : 13)
Query Neighborhood Hits	305	Target Neighborhood Hits	346	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	0.00869519 (rank : 18)	NC score	0.139095 (rank : 14)
Query Neighborhood Hits	305	Target Neighborhood Hits	446	Shared Neighborhood Hits	67
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

APBA3_MOUSE
θ value	0.0113563 (rank : 19)	NC score	0.138929 (rank : 15)
Query Neighborhood Hits	305	Target Neighborhood Hits	174	Shared Neighborhood Hits	42
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SYP2L_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.058461 (rank : 63)
Query Neighborhood Hits	305	Target Neighborhood Hits	400	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

MAST2_HUMAN
θ value	0.0148317 (rank : 21)	NC score	0.021262 (rank : 206)
Query Neighborhood Hits	305	Target Neighborhood Hits	1189	Shared Neighborhood Hits	79
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MLL2_HUMAN
θ value	0.0148317 (rank : 22)	NC score	0.053119 (rank : 73)
Query Neighborhood Hits	305	Target Neighborhood Hits	1788	Shared Neighborhood Hits	144
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TTLL5_MOUSE
θ value	0.0148317 (rank : 23)	NC score	0.036196 (rank : 128)
Query Neighborhood Hits	305	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

CN032_HUMAN
θ value	0.0193708 (rank : 24)	NC score	0.071887 (rank : 41)
Query Neighborhood Hits	305	Target Neighborhood Hits	267	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

APBA2_HUMAN
θ value	0.0252991 (rank : 25)	NC score	0.138626 (rank : 17)
Query Neighborhood Hits	305	Target Neighborhood Hits	220	Shared Neighborhood Hits	44
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.0252991 (rank : 26)	NC score	0.138755 (rank : 16)
Query Neighborhood Hits	305	Target Neighborhood Hits	219	Shared Neighborhood Hits	44
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

NFAC2_MOUSE
θ value	0.0252991 (rank : 27)	NC score	0.040712 (rank : 113)
Query Neighborhood Hits	305	Target Neighborhood Hits	98	Shared Neighborhood Hits	20
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

HCN2_MOUSE
θ value	0.0431538 (rank : 28)	NC score	0.024278 (rank : 188)
Query Neighborhood Hits	305	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

PCLO_HUMAN
θ value	0.0431538 (rank : 29)	NC score	0.071162 (rank : 42)
Query Neighborhood Hits	305	Target Neighborhood Hits	2046	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PKHA4_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.056296 (rank : 67)
Query Neighborhood Hits	305	Target Neighborhood Hits	283	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PDC6I_MOUSE
θ value	0.0563607 (rank : 31)	NC score	0.045015 (rank : 98)
Query Neighborhood Hits	305	Target Neighborhood Hits	275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PO121_HUMAN
θ value	0.0563607 (rank : 32)	NC score	0.051144 (rank : 79)
Query Neighborhood Hits	305	Target Neighborhood Hits	344	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SRRM1_MOUSE
θ value	0.0563607 (rank : 33)	NC score	0.080957 (rank : 28)
Query Neighborhood Hits	305	Target Neighborhood Hits	966	Shared Neighborhood Hits	127
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

APBA3_HUMAN
θ value	0.0736092 (rank : 34)	NC score	0.125528 (rank : 18)
Query Neighborhood Hits	305	Target Neighborhood Hits	201	Shared Neighborhood Hits	44
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

CBP_MOUSE
θ value	0.0736092 (rank : 35)	NC score	0.072149 (rank : 39)
Query Neighborhood Hits	305	Target Neighborhood Hits	1051	Shared Neighborhood Hits	126
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PKHA4_MOUSE
θ value	0.0736092 (rank : 36)	NC score	0.054677 (rank : 71)
Query Neighborhood Hits	305	Target Neighborhood Hits	202	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RD23B_MOUSE
θ value	0.0736092 (rank : 37)	NC score	0.039039 (rank : 119)
Query Neighborhood Hits	305	Target Neighborhood Hits	189	Shared Neighborhood Hits	26
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

SPT5H_HUMAN
θ value	0.0736092 (rank : 38)	NC score	0.076200 (rank : 32)
Query Neighborhood Hits	305	Target Neighborhood Hits	436	Shared Neighborhood Hits	75
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	0.0736092 (rank : 39)	NC score	0.076322 (rank : 30)
Query Neighborhood Hits	305	Target Neighborhood Hits	437	Shared Neighborhood Hits	74
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

APBA1_HUMAN
θ value	0.0961366 (rank : 40)	NC score	0.122378 (rank : 19)
Query Neighborhood Hits	305	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PI5PA_HUMAN
θ value	0.0961366 (rank : 41)	NC score	0.060127 (rank : 58)
Query Neighborhood Hits	305	Target Neighborhood Hits	749	Shared Neighborhood Hits	106
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRB3_HUMAN
θ value	0.0961366 (rank : 42)	NC score	0.050706 (rank : 82)
Query Neighborhood Hits	305	Target Neighborhood Hits	318	Shared Neighborhood Hits	45
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

TAB3_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.055885 (rank : 68)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

LAP4_MOUSE
θ value	0.125558 (rank : 44)	NC score	0.045619 (rank : 95)
Query Neighborhood Hits	305	Target Neighborhood Hits	590	Shared Neighborhood Hits	56
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LR37A_HUMAN
θ value	0.125558 (rank : 45)	NC score	0.043554 (rank : 102)
Query Neighborhood Hits	305	Target Neighborhood Hits	720	Shared Neighborhood Hits	68
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MAST2_MOUSE
θ value	0.125558 (rank : 46)	NC score	0.019034 (rank : 220)
Query Neighborhood Hits	305	Target Neighborhood Hits	1110	Shared Neighborhood Hits	69
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PCLO_MOUSE
θ value	0.125558 (rank : 47)	NC score	0.072381 (rank : 38)
Query Neighborhood Hits	305	Target Neighborhood Hits	2275	Shared Neighborhood Hits	195
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SRRM1_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.067111 (rank : 47)
Query Neighborhood Hits	305	Target Neighborhood Hits	690	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

GRAP1_HUMAN
θ value	0.163984 (rank : 49)	NC score	0.030664 (rank : 150)
Query Neighborhood Hits	305	Target Neighborhood Hits	944	Shared Neighborhood Hits	53
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

MAST4_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.026968 (rank : 177)
Query Neighborhood Hits	305	Target Neighborhood Hits	1804	Shared Neighborhood Hits	150
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MUC2_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.037318 (rank : 126)
Query Neighborhood Hits	305	Target Neighborhood Hits	906	Shared Neighborhood Hits	72
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MYOC_HUMAN
θ value	0.163984 (rank : 52)	NC score	0.055389 (rank : 69)
Query Neighborhood Hits	305	Target Neighborhood Hits	489	Shared Neighborhood Hits	40
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

SMCA4_HUMAN
θ value	0.163984 (rank : 53)	NC score	0.022596 (rank : 198)
Query Neighborhood Hits	305	Target Neighborhood Hits	597	Shared Neighborhood Hits	60
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

GPTC8_HUMAN
θ value	0.21417 (rank : 54)	NC score	0.044913 (rank : 99)
Query Neighborhood Hits	305	Target Neighborhood Hits	366	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PARD3_MOUSE
θ value	0.21417 (rank : 55)	NC score	0.073442 (rank : 35)
Query Neighborhood Hits	305	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

SRRM2_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.072101 (rank : 40)
Query Neighborhood Hits	305	Target Neighborhood Hits	1296	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

GRAP1_MOUSE
θ value	0.279714 (rank : 57)	NC score	0.030169 (rank : 154)
Query Neighborhood Hits	305	Target Neighborhood Hits	1234	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

MUC7_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.059750 (rank : 59)
Query Neighborhood Hits	305	Target Neighborhood Hits	538	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

RPB1_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.047662 (rank : 87)
Query Neighborhood Hits	305	Target Neighborhood Hits	363	Shared Neighborhood Hits	39
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TARSH_HUMAN
θ value	0.279714 (rank : 60)	NC score	0.072925 (rank : 36)
Query Neighborhood Hits	305	Target Neighborhood Hits	768	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CENPE_HUMAN
θ value	0.365318 (rank : 61)	NC score	0.021764 (rank : 203)
Query Neighborhood Hits	305	Target Neighborhood Hits	2060	Shared Neighborhood Hits	80
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

K1802_MOUSE
θ value	0.365318 (rank : 62)	NC score	0.061976 (rank : 56)
Query Neighborhood Hits	305	Target Neighborhood Hits	1596	Shared Neighborhood Hits	141
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RHG25_HUMAN
θ value	0.365318 (rank : 63)	NC score	0.028737 (rank : 161)
Query Neighborhood Hits	305	Target Neighborhood Hits	550	Shared Neighborhood Hits	47
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RPB1_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.046736 (rank : 92)
Query Neighborhood Hits	305	Target Neighborhood Hits	362	Shared Neighborhood Hits	39
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TAB3_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.057597 (rank : 64)
Query Neighborhood Hits	305	Target Neighborhood Hits	273	Shared Neighborhood Hits	58
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

ARI1A_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.046559 (rank : 93)
Query Neighborhood Hits	305	Target Neighborhood Hits	787	Shared Neighborhood Hits	87
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

FXL19_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.031885 (rank : 141)
Query Neighborhood Hits	305	Target Neighborhood Hits	217	Shared Neighborhood Hits	33
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

MAGI1_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.059654 (rank : 60)
Query Neighborhood Hits	305	Target Neighborhood Hits	388	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MYOM1_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.013449 (rank : 249)
Query Neighborhood Hits	305	Target Neighborhood Hits	415	Shared Neighborhood Hits	14
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NACAM_MOUSE
θ value	0.47712 (rank : 70)	NC score	0.075864 (rank : 33)
Query Neighborhood Hits	305	Target Neighborhood Hits	1866	Shared Neighborhood Hits	165
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RAPH1_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.047321 (rank : 90)
Query Neighborhood Hits	305	Target Neighborhood Hits	593	Shared Neighborhood Hits	75
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RX_MOUSE
θ value	0.47712 (rank : 72)	NC score	0.010748 (rank : 264)
Query Neighborhood Hits	305	Target Neighborhood Hits	429	Shared Neighborhood Hits	18
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

TCRG1_HUMAN
θ value	0.47712 (rank : 73)	NC score	0.038715 (rank : 120)
Query Neighborhood Hits	305	Target Neighborhood Hits	929	Shared Neighborhood Hits	76
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

WASL_HUMAN
θ value	0.47712 (rank : 74)	NC score	0.046962 (rank : 91)
Query Neighborhood Hits	305	Target Neighborhood Hits	312	Shared Neighborhood Hits	48
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

CARD6_HUMAN
θ value	0.62314 (rank : 75)	NC score	0.043296 (rank : 105)
Query Neighborhood Hits	305	Target Neighborhood Hits	145	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

EP15R_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.028915 (rank : 160)
Query Neighborhood Hits	305	Target Neighborhood Hits	1083	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.034394 (rank : 132)
Query Neighborhood Hits	305	Target Neighborhood Hits	1135	Shared Neighborhood Hits	68
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

HXB9_MOUSE
θ value	0.62314 (rank : 78)	NC score	0.013280 (rank : 251)
Query Neighborhood Hits	305	Target Neighborhood Hits	344	Shared Neighborhood Hits	14
SwissProt Accessions	P20615	Gene names	Hoxb9, Hox-2.5, Hoxb-9
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2.5).

RNPC1_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.019221 (rank : 215)
Query Neighborhood Hits	305	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q62176, Q922Z2	Gene names	Rnpc1, Seb4, Seb4l
Domain Architecture
Description	RNA-binding region-containing protein 1 (ssDNA-binding protein SEB4).

SGIP1_MOUSE
θ value	0.62314 (rank : 80)	NC score	0.039904 (rank : 116)
Query Neighborhood Hits	305	Target Neighborhood Hits	180	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SON_HUMAN
θ value	0.62314 (rank : 81)	NC score	0.058983 (rank : 61)
Query Neighborhood Hits	305	Target Neighborhood Hits	1568	Shared Neighborhood Hits	152
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BCL9_HUMAN
θ value	0.813845 (rank : 82)	NC score	0.067884 (rank : 45)
Query Neighborhood Hits	305	Target Neighborhood Hits	1008	Shared Neighborhood Hits	123
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

DDEF1_MOUSE
θ value	0.813845 (rank : 83)	NC score	0.016399 (rank : 232)
Query Neighborhood Hits	305	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

HXA3_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.016012 (rank : 233)
Query Neighborhood Hits	305	Target Neighborhood Hits	535	Shared Neighborhood Hits	40
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

HXA3_MOUSE
θ value	0.813845 (rank : 85)	NC score	0.015814 (rank : 236)
Query Neighborhood Hits	305	Target Neighborhood Hits	558	Shared Neighborhood Hits	43
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

MKL1_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.024689 (rank : 185)
Query Neighborhood Hits	305	Target Neighborhood Hits	232	Shared Neighborhood Hits	32
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MNT_MOUSE
θ value	0.813845 (rank : 87)	NC score	0.038415 (rank : 121)
Query Neighborhood Hits	305	Target Neighborhood Hits	432	Shared Neighborhood Hits	55
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NFAC4_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.031188 (rank : 147)
Query Neighborhood Hits	305	Target Neighborhood Hits	165	Shared Neighborhood Hits	21
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PRR8_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.050182 (rank : 85)
Query Neighborhood Hits	305	Target Neighborhood Hits	217	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

USH1C_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.087365 (rank : 26)
Query Neighborhood Hits	305	Target Neighborhood Hits	327	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.813845 (rank : 91)	NC score	0.091320 (rank : 25)
Query Neighborhood Hits	305	Target Neighborhood Hits	557	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

AAK1_MOUSE
θ value	1.06291 (rank : 92)	NC score	0.013583 (rank : 247)
Query Neighborhood Hits	305	Target Neighborhood Hits	1051	Shared Neighborhood Hits	76
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BLNK_MOUSE
θ value	1.06291 (rank : 93)	NC score	0.035452 (rank : 129)
Query Neighborhood Hits	305	Target Neighborhood Hits	296	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

BSN_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.084568 (rank : 27)
Query Neighborhood Hits	305	Target Neighborhood Hits	2057	Shared Neighborhood Hits	208
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CS007_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.032560 (rank : 137)
Query Neighborhood Hits	305	Target Neighborhood Hits	464	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CSF1_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.045032 (rank : 97)
Query Neighborhood Hits	305	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

GOGA3_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.032422 (rank : 139)
Query Neighborhood Hits	305	Target Neighborhood Hits	1437	Shared Neighborhood Hits	69
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

LAP4_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.040347 (rank : 115)
Query Neighborhood Hits	305	Target Neighborhood Hits	608	Shared Neighborhood Hits	53
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MAGC1_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.023433 (rank : 192)
Query Neighborhood Hits	305	Target Neighborhood Hits	431	Shared Neighborhood Hits	49
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SRRM2_MOUSE
θ value	1.06291 (rank : 100)	NC score	0.074905 (rank : 34)
Query Neighborhood Hits	305	Target Neighborhood Hits	1470	Shared Neighborhood Hits	155
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYNJ1_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.040797 (rank : 112)
Query Neighborhood Hits	305	Target Neighborhood Hits	498	Shared Neighborhood Hits	74
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ADAM8_MOUSE
θ value	1.38821 (rank : 102)	NC score	0.005388 (rank : 297)
Query Neighborhood Hits	305	Target Neighborhood Hits	326	Shared Neighborhood Hits	12
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CN032_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.052051 (rank : 75)
Query Neighborhood Hits	305	Target Neighborhood Hits	233	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

ENAH_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.031894 (rank : 140)
Query Neighborhood Hits	305	Target Neighborhood Hits	784	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FXL19_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.024478 (rank : 186)
Query Neighborhood Hits	305	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

HXB9_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.011647 (rank : 260)
Query Neighborhood Hits	305	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	P17482, Q9H1I1	Gene names	HOXB9, HOX2E
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5).

LRP3_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.009754 (rank : 276)
Query Neighborhood Hits	305	Target Neighborhood Hits	280	Shared Neighborhood Hits	18
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MY18A_MOUSE
θ value	1.38821 (rank : 108)	NC score	0.030590 (rank : 151)
Query Neighborhood Hits	305	Target Neighborhood Hits	1989	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH9_MOUSE
θ value	1.38821 (rank : 109)	NC score	0.030842 (rank : 149)
Query Neighborhood Hits	305	Target Neighborhood Hits	1829	Shared Neighborhood Hits	83
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NHERF_HUMAN
θ value	1.38821 (rank : 110)	NC score	0.101276 (rank : 23)
Query Neighborhood Hits	305	Target Neighborhood Hits	190	Shared Neighborhood Hits	40
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.076227 (rank : 31)
Query Neighborhood Hits	305	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PHC2_MOUSE
θ value	1.38821 (rank : 112)	NC score	0.023798 (rank : 191)
Query Neighborhood Hits	305	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PRP4B_MOUSE
θ value	1.38821 (rank : 113)	NC score	0.007162 (rank : 290)
Query Neighborhood Hits	305	Target Neighborhood Hits	1040	Shared Neighborhood Hits	39
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

RP3A_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.013504 (rank : 248)
Query Neighborhood Hits	305	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TCRG1_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.038104 (rank : 123)
Query Neighborhood Hits	305	Target Neighborhood Hits	947	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TERF2_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.025349 (rank : 181)
Query Neighborhood Hits	305	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TUFT1_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.029266 (rank : 159)
Query Neighborhood Hits	305	Target Neighborhood Hits	686	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

WDR46_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.027999 (rank : 169)
Query Neighborhood Hits	305	Target Neighborhood Hits	147	Shared Neighborhood Hits	10
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

WDR46_MOUSE
θ value	1.38821 (rank : 119)	NC score	0.038096 (rank : 124)
Query Neighborhood Hits	305	Target Neighborhood Hits	243	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

ZIM2_HUMAN
θ value	1.38821 (rank : 120)	NC score	-0.001164 (rank : 316)
Query Neighborhood Hits	305	Target Neighborhood Hits	718	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZV7	Gene names	ZIM2
Domain Architecture
Description	Zinc finger imprinted 2.

BRSK2_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.003849 (rank : 304)
Query Neighborhood Hits	305	Target Neighborhood Hits	897	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

EGR1_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.000021 (rank : 314)
Query Neighborhood Hits	305	Target Neighborhood Hits	788	Shared Neighborhood Hits	21
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

GOGA3_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.030560 (rank : 152)
Query Neighborhood Hits	305	Target Neighborhood Hits	1317	Shared Neighborhood Hits	80
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

JADE2_MOUSE
θ value	1.81305 (rank : 124)	NC score	0.030116 (rank : 156)
Query Neighborhood Hits	305	Target Neighborhood Hits	560	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MAGI1_MOUSE
θ value	1.81305 (rank : 125)	NC score	0.056420 (rank : 66)
Query Neighborhood Hits	305	Target Neighborhood Hits	403	Shared Neighborhood Hits	58
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PRG3_MOUSE
θ value	1.81305 (rank : 126)	NC score	0.015930 (rank : 235)
Query Neighborhood Hits	305	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

PRG4_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.041848 (rank : 110)
Query Neighborhood Hits	305	Target Neighborhood Hits	764	Shared Neighborhood Hits	80
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRR12_HUMAN
θ value	1.81305 (rank : 128)	NC score	0.050657 (rank : 83)
Query Neighborhood Hits	305	Target Neighborhood Hits	460	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RNPC1_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.015375 (rank : 240)
Query Neighborhood Hits	305	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0Z9, Q15350, Q15351, Q9BYK3, Q9BYK4	Gene names	RNPC1, SEB4
Domain Architecture
Description	RNA-binding region-containing protein 1 (HSRNASEB) (ssDNA-binding protein SEB4) (CLL-associated antigen KW-5).

SF3B1_HUMAN
θ value	1.81305 (rank : 130)	NC score	0.047739 (rank : 86)
Query Neighborhood Hits	305	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	1.81305 (rank : 131)	NC score	0.047631 (rank : 88)
Query Neighborhood Hits	305	Target Neighborhood Hits	352	Shared Neighborhood Hits	57
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SSH1_MOUSE
θ value	1.81305 (rank : 132)	NC score	0.009783 (rank : 275)
Query Neighborhood Hits	305	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

TCOF_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.033669 (rank : 136)
Query Neighborhood Hits	305	Target Neighborhood Hits	543	Shared Neighborhood Hits	59
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TFG_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.043460 (rank : 103)
Query Neighborhood Hits	305	Target Neighborhood Hits	122	Shared Neighborhood Hits	19
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

WASL_MOUSE
θ value	1.81305 (rank : 135)	NC score	0.047334 (rank : 89)
Query Neighborhood Hits	305	Target Neighborhood Hits	339	Shared Neighborhood Hits	55
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

ZEP1_MOUSE
θ value	1.81305 (rank : 136)	NC score	0.013222 (rank : 253)
Query Neighborhood Hits	305	Target Neighborhood Hits	1063	Shared Neighborhood Hits	61
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ASTL_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.025120 (rank : 182)
Query Neighborhood Hits	305	Target Neighborhood Hits	252	Shared Neighborhood Hits	42
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BAG3_MOUSE
θ value	2.36792 (rank : 138)	NC score	0.046039 (rank : 94)
Query Neighborhood Hits	305	Target Neighborhood Hits	513	Shared Neighborhood Hits	87
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BRD8_MOUSE
θ value	2.36792 (rank : 139)	NC score	0.031477 (rank : 142)
Query Neighborhood Hits	305	Target Neighborhood Hits	422	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BSN_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.067559 (rank : 46)
Query Neighborhood Hits	305	Target Neighborhood Hits	1537	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CAMKV_HUMAN
θ value	2.36792 (rank : 141)	NC score	0.009027 (rank : 279)
Query Neighborhood Hits	305	Target Neighborhood Hits	1084	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CIC_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.039121 (rank : 118)
Query Neighborhood Hits	305	Target Neighborhood Hits	992	Shared Neighborhood Hits	121
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CNOT3_MOUSE
θ value	2.36792 (rank : 143)	NC score	0.034174 (rank : 133)
Query Neighborhood Hits	305	Target Neighborhood Hits	504	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DCP1B_HUMAN
θ value	2.36792 (rank : 144)	NC score	0.032510 (rank : 138)
Query Neighborhood Hits	305	Target Neighborhood Hits	118	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

FOSB_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.019916 (rank : 212)
Query Neighborhood Hits	305	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

G6B_HUMAN
θ value	2.36792 (rank : 146)	NC score	0.031092 (rank : 148)
Query Neighborhood Hits	305	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	O95866, Q96A86, Q96A87, Q96A88, Q96A89, Q96A90, Q96A91	Gene names	G6B, C6orf25
Domain Architecture	No domain graphic available
Description	G6b protein precursor.

HXC4_MOUSE
θ value	2.36792 (rank : 147)	NC score	0.008657 (rank : 280)
Query Neighborhood Hits	305	Target Neighborhood Hits	365	Shared Neighborhood Hits	17
SwissProt Accessions	Q08624	Gene names	Hoxc4, Hox-3.5, Hoxc-4
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3.5).

JIP2_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.020801 (rank : 208)
Query Neighborhood Hits	305	Target Neighborhood Hits	288	Shared Neighborhood Hits	30
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

K1802_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.040414 (rank : 114)
Query Neighborhood Hits	305	Target Neighborhood Hits	1378	Shared Neighborhood Hits	126
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNH3_MOUSE
θ value	2.36792 (rank : 150)	NC score	0.010683 (rank : 265)
Query Neighborhood Hits	305	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

MAST1_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.015540 (rank : 237)
Query Neighborhood Hits	305	Target Neighborhood Hits	1146	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	2.36792 (rank : 152)	NC score	0.015121 (rank : 243)
Query Neighborhood Hits	305	Target Neighborhood Hits	1123	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MPP10_MOUSE
θ value	2.36792 (rank : 153)	NC score	0.020745 (rank : 209)
Query Neighborhood Hits	305	Target Neighborhood Hits	251	Shared Neighborhood Hits	21
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MYH11_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.027203 (rank : 175)
Query Neighborhood Hits	305	Target Neighborhood Hits	1806	Shared Neighborhood Hits	79
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_HUMAN
θ value	2.36792 (rank : 155)	NC score	0.030044 (rank : 157)
Query Neighborhood Hits	305	Target Neighborhood Hits	1762	Shared Neighborhood Hits	76
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PHLB1_HUMAN
θ value	2.36792 (rank : 156)	NC score	0.042827 (rank : 106)
Query Neighborhood Hits	305	Target Neighborhood Hits	1038	Shared Neighborhood Hits	107
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.039745 (rank : 117)
Query Neighborhood Hits	305	Target Neighborhood Hits	678	Shared Neighborhood Hits	84
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRDM1_HUMAN
θ value	2.36792 (rank : 158)	NC score	-0.001363 (rank : 317)
Query Neighborhood Hits	305	Target Neighborhood Hits	734	Shared Neighborhood Hits	15
SwissProt Accessions	O75626	Gene names	PRDM1, BLIMP1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1) (Positive regulatory domain I-binding factor 1) (PRDI- binding factor 1) (PRDI-BF1).

RNPS1_HUMAN
θ value	2.36792 (rank : 159)	NC score	0.017899 (rank : 224)
Query Neighborhood Hits	305	Target Neighborhood Hits	285	Shared Neighborhood Hits	15
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	2.36792 (rank : 160)	NC score	0.017899 (rank : 225)
Query Neighborhood Hits	305	Target Neighborhood Hits	285	Shared Neighborhood Hits	15
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SYN1_HUMAN
θ value	2.36792 (rank : 161)	NC score	0.033717 (rank : 134)
Query Neighborhood Hits	305	Target Neighborhood Hits	419	Shared Neighborhood Hits	54
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYNJ1_MOUSE
θ value	2.36792 (rank : 162)	NC score	0.041456 (rank : 111)
Query Neighborhood Hits	305	Target Neighborhood Hits	516	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ZEP1_HUMAN
θ value	2.36792 (rank : 163)	NC score	0.015537 (rank : 238)
Query Neighborhood Hits	305	Target Neighborhood Hits	1036	Shared Neighborhood Hits	68
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ZN497_HUMAN
θ value	2.36792 (rank : 164)	NC score	-0.002717 (rank : 318)
Query Neighborhood Hits	305	Target Neighborhood Hits	748	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZNH5, Q6ZTD2, Q9UIA8	Gene names	ZNF497
Domain Architecture	No domain graphic available
Description	Zinc finger protein 497.

ARHGB_HUMAN
θ value	3.0926 (rank : 165)	NC score	0.063300 (rank : 54)
Query Neighborhood Hits	305	Target Neighborhood Hits	375	Shared Neighborhood Hits	52
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ATN1_HUMAN
θ value	3.0926 (rank : 166)	NC score	0.041869 (rank : 109)
Query Neighborhood Hits	305	Target Neighborhood Hits	676	Shared Neighborhood Hits	82
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BRD4_MOUSE
θ value	3.0926 (rank : 167)	NC score	0.036580 (rank : 127)
Query Neighborhood Hits	305	Target Neighborhood Hits	845	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CECR2_HUMAN
θ value	3.0926 (rank : 168)	NC score	0.044641 (rank : 100)
Query Neighborhood Hits	305	Target Neighborhood Hits	543	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CT174_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.031194 (rank : 146)
Query Neighborhood Hits	305	Target Neighborhood Hits	181	Shared Neighborhood Hits	33
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DIDO1_HUMAN
θ value	3.0926 (rank : 170)	NC score	0.042121 (rank : 108)
Query Neighborhood Hits	305	Target Neighborhood Hits	960	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DOCK4_MOUSE
θ value	3.0926 (rank : 171)	NC score	0.022191 (rank : 199)
Query Neighborhood Hits	305	Target Neighborhood Hits	210	Shared Neighborhood Hits	41
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

FA5_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.015264 (rank : 242)
Query Neighborhood Hits	305	Target Neighborhood Hits	172	Shared Neighborhood Hits	21
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

GPSM1_MOUSE
θ value	3.0926 (rank : 173)	NC score	0.010107 (rank : 269)
Query Neighborhood Hits	305	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q6IR34, Q61366, Q8BUK4, Q8BX78, Q8R0R9	Gene names	Gpsm1, Ags3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

HDAC4_HUMAN
θ value	3.0926 (rank : 174)	NC score	0.011371 (rank : 261)
Query Neighborhood Hits	305	Target Neighborhood Hits	390	Shared Neighborhood Hits	33
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

HRX_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.028659 (rank : 162)
Query Neighborhood Hits	305	Target Neighborhood Hits	825	Shared Neighborhood Hits	67
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IQEC2_HUMAN
θ value	3.0926 (rank : 176)	NC score	0.026211 (rank : 179)
Query Neighborhood Hits	305	Target Neighborhood Hits	403	Shared Neighborhood Hits	49
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	3.0926 (rank : 177)	NC score	0.026341 (rank : 178)
Query Neighborhood Hits	305	Target Neighborhood Hits	417	Shared Neighborhood Hits	49
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

K1688_HUMAN
θ value	3.0926 (rank : 178)	NC score	0.027708 (rank : 170)
Query Neighborhood Hits	305	Target Neighborhood Hits	217	Shared Neighborhood Hits	35
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

LSD1_MOUSE
θ value	3.0926 (rank : 179)	NC score	0.014447 (rank : 244)
Query Neighborhood Hits	305	Target Neighborhood Hits	224	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MINT_MOUSE
θ value	3.0926 (rank : 180)	NC score	0.038234 (rank : 122)
Query Neighborhood Hits	305	Target Neighborhood Hits	1514	Shared Neighborhood Hits	135
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MK07_MOUSE
θ value	3.0926 (rank : 181)	NC score	0.004945 (rank : 300)
Query Neighborhood Hits	305	Target Neighborhood Hits	1054	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MYH10_HUMAN
θ value	3.0926 (rank : 182)	NC score	0.028599 (rank : 163)
Query Neighborhood Hits	305	Target Neighborhood Hits	1620	Shared Neighborhood Hits	80
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	3.0926 (rank : 183)	NC score	0.028362 (rank : 164)
Query Neighborhood Hits	305	Target Neighborhood Hits	1612	Shared Neighborhood Hits	81
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_MOUSE
θ value	3.0926 (rank : 184)	NC score	0.028278 (rank : 165)
Query Neighborhood Hits	305	Target Neighborhood Hits	1777	Shared Neighborhood Hits	74
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYO5A_HUMAN
θ value	3.0926 (rank : 185)	NC score	0.022919 (rank : 196)
Query Neighborhood Hits	305	Target Neighborhood Hits	1092	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NBEA_MOUSE
θ value	3.0926 (rank : 186)	NC score	0.009444 (rank : 277)
Query Neighborhood Hits	305	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

NFAC2_HUMAN
θ value	3.0926 (rank : 187)	NC score	0.030153 (rank : 155)
Query Neighborhood Hits	305	Target Neighborhood Hits	101	Shared Neighborhood Hits	23
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

NHERF_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.094146 (rank : 24)
Query Neighborhood Hits	305	Target Neighborhood Hits	195	Shared Neighborhood Hits	41
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PHF8_HUMAN
θ value	3.0926 (rank : 189)	NC score	0.010459 (rank : 266)
Query Neighborhood Hits	305	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PO6F2_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.015984 (rank : 234)
Query Neighborhood Hits	305	Target Neighborhood Hits	618	Shared Neighborhood Hits	47
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

SNPC4_HUMAN
θ value	3.0926 (rank : 191)	NC score	0.044198 (rank : 101)
Query Neighborhood Hits	305	Target Neighborhood Hits	589	Shared Neighborhood Hits	98
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

TPR_HUMAN
θ value	3.0926 (rank : 192)	NC score	0.031472 (rank : 143)
Query Neighborhood Hits	305	Target Neighborhood Hits	1921	Shared Neighborhood Hits	100
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRIPB_HUMAN
θ value	3.0926 (rank : 193)	NC score	0.023837 (rank : 190)
Query Neighborhood Hits	305	Target Neighborhood Hits	1587	Shared Neighborhood Hits	76
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

U520_HUMAN
θ value	3.0926 (rank : 194)	NC score	0.012692 (rank : 256)
Query Neighborhood Hits	305	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

WNK1_HUMAN
θ value	3.0926 (rank : 195)	NC score	0.007431 (rank : 289)
Query Neighborhood Hits	305	Target Neighborhood Hits	1158	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ADCY3_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.004765 (rank : 301)
Query Neighborhood Hits	305	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O60266, Q9UDB1	Gene names	ADCY3, KIAA0511
Domain Architecture
Description	Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III) (Adenylate cyclase, olfactive type) (ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3).

ANX11_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.009882 (rank : 273)
Query Neighborhood Hits	305	Target Neighborhood Hits	192	Shared Neighborhood Hits	28
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

ATX2_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.023395 (rank : 193)
Query Neighborhood Hits	305	Target Neighborhood Hits	375	Shared Neighborhood Hits	48
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

BASP_HUMAN
θ value	4.03905 (rank : 199)	NC score	0.033701 (rank : 135)
Query Neighborhood Hits	305	Target Neighborhood Hits	321	Shared Neighborhood Hits	38
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BCL9_MOUSE
θ value	4.03905 (rank : 200)	NC score	0.054599 (rank : 72)
Query Neighborhood Hits	305	Target Neighborhood Hits	770	Shared Neighborhood Hits	107
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CING_MOUSE
θ value	4.03905 (rank : 201)	NC score	0.022059 (rank : 200)
Query Neighborhood Hits	305	Target Neighborhood Hits	1432	Shared Neighborhood Hits	73
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CO5A3_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.008166 (rank : 283)
Query Neighborhood Hits	305	Target Neighborhood Hits	433	Shared Neighborhood Hits	30
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CSKI1_MOUSE
θ value	4.03905 (rank : 203)	NC score	0.023899 (rank : 189)
Query Neighborhood Hits	305	Target Neighborhood Hits	1031	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CTGE5_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.017237 (rank : 227)
Query Neighborhood Hits	305	Target Neighborhood Hits	800	Shared Neighborhood Hits	46
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DIAP1_HUMAN
θ value	4.03905 (rank : 205)	NC score	0.025000 (rank : 184)
Query Neighborhood Hits	305	Target Neighborhood Hits	784	Shared Neighborhood Hits	75
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DOK7_MOUSE
θ value	4.03905 (rank : 206)	NC score	0.024469 (rank : 187)
Query Neighborhood Hits	305	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

LMD1_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.013444 (rank : 250)
Query Neighborhood Hits	305	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

LMNB2_MOUSE
θ value	4.03905 (rank : 208)	NC score	0.019077 (rank : 219)
Query Neighborhood Hits	305	Target Neighborhood Hits	674	Shared Neighborhood Hits	45
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

MDC1_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.066118 (rank : 48)
Query Neighborhood Hits	305	Target Neighborhood Hits	1446	Shared Neighborhood Hits	148
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NEMO_MOUSE
θ value	4.03905 (rank : 210)	NC score	0.025642 (rank : 180)
Query Neighborhood Hits	305	Target Neighborhood Hits	658	Shared Neighborhood Hits	55
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NUMA1_HUMAN
θ value	4.03905 (rank : 211)	NC score	0.028096 (rank : 167)
Query Neighborhood Hits	305	Target Neighborhood Hits	1523	Shared Neighborhood Hits	78
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PI5PA_MOUSE
θ value	4.03905 (rank : 212)	NC score	0.042434 (rank : 107)
Query Neighborhood Hits	305	Target Neighborhood Hits	331	Shared Neighborhood Hits	56
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SC24A_MOUSE
θ value	4.03905 (rank : 213)	NC score	0.029467 (rank : 158)
Query Neighborhood Hits	305	Target Neighborhood Hits	394	Shared Neighborhood Hits	66
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

STK10_HUMAN
θ value	4.03905 (rank : 214)	NC score	0.010080 (rank : 270)
Query Neighborhood Hits	305	Target Neighborhood Hits	1921	Shared Neighborhood Hits	95
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TITIN_HUMAN
θ value	4.03905 (rank : 215)	NC score	0.008652 (rank : 281)
Query Neighborhood Hits	305	Target Neighborhood Hits	2923	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TLN1_HUMAN
θ value	4.03905 (rank : 216)	NC score	0.012346 (rank : 259)
Query Neighborhood Hits	305	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	4.03905 (rank : 217)	NC score	0.016990 (rank : 229)
Query Neighborhood Hits	305	Target Neighborhood Hits	213	Shared Neighborhood Hits	16
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

ZDHC5_MOUSE
θ value	4.03905 (rank : 218)	NC score	0.008097 (rank : 285)
Query Neighborhood Hits	305	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

ZN219_HUMAN
θ value	4.03905 (rank : 219)	NC score	0.002307 (rank : 311)
Query Neighborhood Hits	305	Target Neighborhood Hits	876	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

ALMS1_HUMAN
θ value	5.27518 (rank : 220)	NC score	0.027462 (rank : 174)
Query Neighborhood Hits	305	Target Neighborhood Hits	356	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

ANKS6_MOUSE
θ value	5.27518 (rank : 221)	NC score	0.007090 (rank : 291)
Query Neighborhood Hits	305	Target Neighborhood Hits	435	Shared Neighborhood Hits	28
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR25_HUMAN
θ value	5.27518 (rank : 222)	NC score	0.008146 (rank : 284)
Query Neighborhood Hits	305	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANX11_MOUSE
θ value	5.27518 (rank : 223)	NC score	0.010403 (rank : 267)
Query Neighborhood Hits	305	Target Neighborhood Hits	200	Shared Neighborhood Hits	24
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

AZI1_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.028112 (rank : 166)
Query Neighborhood Hits	305	Target Neighborhood Hits	1000	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

B4GN3_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.013949 (rank : 245)
Query Neighborhood Hits	305	Target Neighborhood Hits	128	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

CLIC6_HUMAN
θ value	5.27518 (rank : 226)	NC score	0.008553 (rank : 282)
Query Neighborhood Hits	305	Target Neighborhood Hits	289	Shared Neighborhood Hits	26
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CN065_HUMAN
θ value	5.27518 (rank : 227)	NC score	0.021937 (rank : 201)
Query Neighborhood Hits	305	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N9R9	Gene names	C14orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf65.

CYTSA_HUMAN
θ value	5.27518 (rank : 228)	NC score	0.027157 (rank : 176)
Query Neighborhood Hits	305	Target Neighborhood Hits	1138	Shared Neighborhood Hits	72
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

FA53B_MOUSE
θ value	5.27518 (rank : 229)	NC score	0.012419 (rank : 258)
Query Neighborhood Hits	305	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGR5, Q3UGW1, Q8BI13	Gene names	Fam53b
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

FOSB_MOUSE
θ value	5.27518 (rank : 230)	NC score	0.016666 (rank : 231)
Query Neighborhood Hits	305	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

GON4L_HUMAN
θ value	5.27518 (rank : 231)	NC score	0.022998 (rank : 195)
Query Neighborhood Hits	305	Target Neighborhood Hits	555	Shared Neighborhood Hits	64
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GP156_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.013274 (rank : 252)
Query Neighborhood Hits	305	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

LIRA4_HUMAN
θ value	5.27518 (rank : 233)	NC score	0.003737 (rank : 305)
Query Neighborhood Hits	305	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P59901	Gene names	LILRA4, ILT7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 4 precursor (Immunoglobulin-like transcript 7) (ILT-7) (CD85g antigen).

LMNB2_HUMAN
θ value	5.27518 (rank : 234)	NC score	0.016749 (rank : 230)
Query Neighborhood Hits	305	Target Neighborhood Hits	723	Shared Neighborhood Hits	49
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

MYH13_HUMAN
θ value	5.27518 (rank : 235)	NC score	0.019810 (rank : 213)
Query Neighborhood Hits	305	Target Neighborhood Hits	1504	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYO15_HUMAN
θ value	5.27518 (rank : 236)	NC score	0.031353 (rank : 145)
Query Neighborhood Hits	305	Target Neighborhood Hits	671	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO9B_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.022874 (rank : 197)
Query Neighborhood Hits	305	Target Neighborhood Hits	641	Shared Neighborhood Hits	77
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PARD3_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.063559 (rank : 52)
Query Neighborhood Hits	305	Target Neighborhood Hits	312	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDZD1_HUMAN
θ value	5.27518 (rank : 239)	NC score	0.068074 (rank : 44)
Query Neighborhood Hits	305	Target Neighborhood Hits	190	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PHAR2_HUMAN
θ value	5.27518 (rank : 240)	NC score	0.019189 (rank : 217)
Query Neighborhood Hits	305	Target Neighborhood Hits	208	Shared Neighborhood Hits	23
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

PTN23_MOUSE
θ value	5.27518 (rank : 241)	NC score	0.023298 (rank : 194)
Query Neighborhood Hits	305	Target Neighborhood Hits	726	Shared Neighborhood Hits	89
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

R3HD1_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.027667 (rank : 171)
Query Neighborhood Hits	305	Target Neighborhood Hits	203	Shared Neighborhood Hits	41
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

RHG06_HUMAN
θ value	5.27518 (rank : 243)	NC score	0.009934 (rank : 272)
Query Neighborhood Hits	305	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RUFY1_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.037380 (rank : 125)
Query Neighborhood Hits	305	Target Neighborhood Hits	848	Shared Neighborhood Hits	56
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SOCS6_MOUSE
θ value	5.27518 (rank : 245)	NC score	0.008032 (rank : 286)
Query Neighborhood Hits	305	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

STYK1_MOUSE
θ value	5.27518 (rank : 246)	NC score	-0.000045 (rank : 315)
Query Neighborhood Hits	305	Target Neighborhood Hits	779	Shared Neighborhood Hits	17
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

TNNI2_MOUSE
θ value	5.27518 (rank : 247)	NC score	0.013618 (rank : 246)
Query Neighborhood Hits	305	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	P13412	Gene names	Tnni2
Domain Architecture
Description	Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).

BEGIN_MOUSE
θ value	6.88961 (rank : 248)	NC score	0.018549 (rank : 221)
Query Neighborhood Hits	305	Target Neighborhood Hits	383	Shared Neighborhood Hits	39
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

BPAEA_MOUSE
θ value	6.88961 (rank : 249)	NC score	0.020874 (rank : 207)
Query Neighborhood Hits	305	Target Neighborhood Hits	1480	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CD2L7_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.005202 (rank : 298)
Query Neighborhood Hits	305	Target Neighborhood Hits	1275	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CSKI2_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.015454 (rank : 239)
Query Neighborhood Hits	305	Target Neighborhood Hits	747	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSPG2_MOUSE
θ value	6.88961 (rank : 252)	NC score	0.006216 (rank : 295)
Query Neighborhood Hits	305	Target Neighborhood Hits	711	Shared Neighborhood Hits	41
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DPOE1_HUMAN
θ value	6.88961 (rank : 253)	NC score	0.010267 (rank : 268)
Query Neighborhood Hits	305	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DYN1_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.010979 (rank : 263)
Query Neighborhood Hits	305	Target Neighborhood Hits	216	Shared Neighborhood Hits	40
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

F125B_HUMAN
θ value	6.88961 (rank : 255)	NC score	0.009943 (rank : 271)
Query Neighborhood Hits	305	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7P6, Q8N6S7	Gene names	FAM125B, C9orf28
Domain Architecture	No domain graphic available
Description	Protein FAM125B.

FBSH_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.017339 (rank : 226)
Query Neighborhood Hits	305	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R089	Gene names	Fbs1, Fbs
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

GCNL2_HUMAN
θ value	6.88961 (rank : 257)	NC score	0.017149 (rank : 228)
Query Neighborhood Hits	305	Target Neighborhood Hits	159	Shared Neighborhood Hits	28
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

IASPP_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.018402 (rank : 222)
Query Neighborhood Hits	305	Target Neighborhood Hits	688	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF4G1_HUMAN
θ value	6.88961 (rank : 259)	NC score	0.019572 (rank : 214)
Query Neighborhood Hits	305	Target Neighborhood Hits	347	Shared Neighborhood Hits	49
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

LIPB2_HUMAN
θ value	6.88961 (rank : 260)	NC score	0.019120 (rank : 218)
Query Neighborhood Hits	305	Target Neighborhood Hits	599	Shared Neighborhood Hits	52
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

MLL3_MOUSE
θ value	6.88961 (rank : 261)	NC score	0.050543 (rank : 84)
Query Neighborhood Hits	305	Target Neighborhood Hits	1399	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NCOA6_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.065988 (rank : 49)
Query Neighborhood Hits	305	Target Neighborhood Hits	1202	Shared Neighborhood Hits	149
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NEK1_HUMAN
θ value	6.88961 (rank : 263)	NC score	0.003005 (rank : 309)
Query Neighborhood Hits	305	Target Neighborhood Hits	1129	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

PHC2_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.034915 (rank : 131)
Query Neighborhood Hits	305	Target Neighborhood Hits	388	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

PTN13_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.028050 (rank : 168)
Query Neighborhood Hits	305	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

RIN3_HUMAN
θ value	6.88961 (rank : 266)	NC score	0.020015 (rank : 210)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RXRG_HUMAN
θ value	6.88961 (rank : 267)	NC score	0.000618 (rank : 313)
Query Neighborhood Hits	305	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

SIN3A_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.013048 (rank : 254)
Query Neighborhood Hits	305	Target Neighborhood Hits	180	Shared Neighborhood Hits	32
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

AFF4_HUMAN
θ value	8.99809 (rank : 269)	NC score	0.015356 (rank : 241)
Query Neighborhood Hits	305	Target Neighborhood Hits	611	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

BCLF1_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.019927 (rank : 211)
Query Neighborhood Hits	305	Target Neighborhood Hits	298	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BCLF1_MOUSE
θ value	8.99809 (rank : 271)	NC score	0.021872 (rank : 202)
Query Neighborhood Hits	305	Target Neighborhood Hits	303	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

CCDC9_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.012532 (rank : 257)
Query Neighborhood Hits	305	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CCNL2_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.006310 (rank : 294)
Query Neighborhood Hits	305	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

CENG1_MOUSE
θ value	8.99809 (rank : 274)	NC score	0.005919 (rank : 296)
Query Neighborhood Hits	305	Target Neighborhood Hits	531	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

DEN2A_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.004752 (rank : 302)
Query Neighborhood Hits	305	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

FMNL_HUMAN
θ value	8.99809 (rank : 276)	NC score	0.021675 (rank : 204)
Query Neighborhood Hits	305	Target Neighborhood Hits	529	Shared Neighborhood Hits	65
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

FOXF2_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.001389 (rank : 312)
Query Neighborhood Hits	305	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

GALT5_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.003702 (rank : 306)
Query Neighborhood Hits	305	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M9, Q9UGK7, Q9UHL6	Gene names	GALNT5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

GALT5_MOUSE
θ value	8.99809 (rank : 279)	NC score	0.003494 (rank : 307)
Query Neighborhood Hits	305	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C102	Gene names	Galnt5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

GDF5_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.002809 (rank : 310)
Query Neighborhood Hits	305	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

HIC2_MOUSE
θ value	8.99809 (rank : 281)	NC score	-0.002911 (rank : 319)
Query Neighborhood Hits	305	Target Neighborhood Hits	821	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).

HXC4_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.006769 (rank : 293)
Query Neighborhood Hits	305	Target Neighborhood Hits	361	Shared Neighborhood Hits	16
SwissProt Accessions	P09017	Gene names	HOXC4, HOX3E
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3E) (CP19).

IF35_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.019198 (rank : 216)
Query Neighborhood Hits	305	Target Neighborhood Hits	210	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IMPG1_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.009073 (rank : 278)
Query Neighborhood Hits	305	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

LDB3_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.018301 (rank : 223)
Query Neighborhood Hits	305	Target Neighborhood Hits	497	Shared Neighborhood Hits	62
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LRC50_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.009813 (rank : 274)
Query Neighborhood Hits	305	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MPDZ_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.045068 (rank : 96)
Query Neighborhood Hits	305	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
θ value	8.99809 (rank : 288)	NC score	0.043356 (rank : 104)
Query Neighborhood Hits	305	Target Neighborhood Hits	298	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MY18A_HUMAN
θ value	8.99809 (rank : 289)	NC score	0.027591 (rank : 172)
Query Neighborhood Hits	305	Target Neighborhood Hits	1929	Shared Neighborhood Hits	106
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYO5A_MOUSE
θ value	8.99809 (rank : 290)	NC score	0.021479 (rank : 205)
Query Neighborhood Hits	305	Target Neighborhood Hits	1117	Shared Neighborhood Hits	61
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

NAF1_MOUSE
θ value	8.99809 (rank : 291)	NC score	0.030394 (rank : 153)
Query Neighborhood Hits	305	Target Neighborhood Hits	852	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PCQAP_HUMAN
θ value	8.99809 (rank : 292)	NC score	0.035004 (rank : 130)
Query Neighborhood Hits	305	Target Neighborhood Hits	549	Shared Neighborhood Hits	71
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PGCB_MOUSE
θ value	8.99809 (rank : 293)	NC score	0.003428 (rank : 308)
Query Neighborhood Hits	305	Target Neighborhood Hits	459	Shared Neighborhood Hits	19
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PYGO2_HUMAN
θ value	8.99809 (rank : 294)	NC score	0.025057 (rank : 183)
Query Neighborhood Hits	305	Target Neighborhood Hits	189	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RC3H1_MOUSE
θ value	8.99809 (rank : 295)	NC score	0.005049 (rank : 299)
Query Neighborhood Hits	305	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RUSC1_MOUSE
θ value	8.99809 (rank : 296)	NC score	0.006826 (rank : 292)
Query Neighborhood Hits	305	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SELPL_MOUSE
θ value	8.99809 (rank : 297)	NC score	0.057467 (rank : 65)
Query Neighborhood Hits	305	Target Neighborhood Hits	588	Shared Neighborhood Hits	90
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SF3B4_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.012883 (rank : 255)
Query Neighborhood Hits	305	Target Neighborhood Hits	445	Shared Neighborhood Hits	40
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SGIP1_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.031454 (rank : 144)
Query Neighborhood Hits	305	Target Neighborhood Hits	198	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SORC3_HUMAN
θ value	8.99809 (rank : 300)	NC score	0.004192 (rank : 303)
Query Neighborhood Hits	305	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

TACC3_HUMAN
θ value	8.99809 (rank : 301)	NC score	0.027538 (rank : 173)
Query Neighborhood Hits	305	Target Neighborhood Hits	779	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TARA_HUMAN
θ value	8.99809 (rank : 302)	NC score	0.055049 (rank : 70)
Query Neighborhood Hits	305	Target Neighborhood Hits	1626	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TNNI2_HUMAN
θ value	8.99809 (rank : 303)	NC score	0.011130 (rank : 262)
Query Neighborhood Hits	305	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	P48788	Gene names	TNNI2
Domain Architecture
Description	Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).

WWOX_HUMAN
θ value	8.99809 (rank : 304)	NC score	0.007617 (rank : 287)
Query Neighborhood Hits	305	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
θ value	8.99809 (rank : 305)	NC score	0.007477 (rank : 288)
Query Neighborhood Hits	305	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

EP300_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.051582 (rank : 76)
Query Neighborhood Hits	305	Target Neighborhood Hits	821	Shared Neighborhood Hits	92
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MDC1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.063599 (rank : 51)
Query Neighborhood Hits	305	Target Neighborhood Hits	998	Shared Neighborhood Hits	115
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MLL3_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.052968 (rank : 74)
Query Neighborhood Hits	305	Target Neighborhood Hits	1644	Shared Neighborhood Hits	150
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MUC1_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.065352 (rank : 50)
Query Neighborhood Hits	305	Target Neighborhood Hits	975	Shared Neighborhood Hits	120
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.051137 (rank : 80)
Query Neighborhood Hits	305	Target Neighborhood Hits	1076	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NHRF2_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.068119 (rank : 43)
Query Neighborhood Hits	305	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

OGFR_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.060722 (rank : 57)
Query Neighborhood Hits	305	Target Neighborhood Hits	1582	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PDZD1_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.051390 (rank : 78)
Query Neighborhood Hits	305	Target Neighborhood Hits	191	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD3_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.050755 (rank : 81)
Query Neighborhood Hits	305	Target Neighborhood Hits	180	Shared Neighborhood Hits	38
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD3_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.080243 (rank : 29)
Query Neighborhood Hits	305	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PRRT3_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.063301 (rank : 53)
Query Neighborhood Hits	305	Target Neighborhood Hits	998	Shared Neighborhood Hits	134
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RGS3_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.051551 (rank : 77)
Query Neighborhood Hits	305	Target Neighborhood Hits	1621	Shared Neighborhood Hits	176
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

WHRN_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.058534 (rank : 62)
Query Neighborhood Hits	305	Target Neighborhood Hits	325	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.062944 (rank : 55)
Query Neighborhood Hits	305	Target Neighborhood Hits	412	Shared Neighborhood Hits	75
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

Hits sorted by NC score

SI1L3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	305	Target Neighborhood Hits	305	Shared Neighborhood Hits	305
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SI1L2_MOUSE
NC score	0.957882 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	305	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_HUMAN
NC score	0.956940 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	305	Target Neighborhood Hits	131	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L1_HUMAN
NC score	0.954631 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	305	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
NC score	0.952997 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	305	Target Neighborhood Hits	189	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SIPA1_MOUSE
NC score	0.925413 (rank : 6)	θ value	7.25522e-167 (rank : 7)
Query Neighborhood Hits	305	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SIPA1_HUMAN
NC score	0.917505 (rank : 7)	θ value	5.18743e-173 (rank : 6)
Query Neighborhood Hits	305	Target Neighborhood Hits	250	Shared Neighborhood Hits	55
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

RGP2_HUMAN
NC score	0.874658 (rank : 8)	θ value	1.45929e-58 (rank : 8)
Query Neighborhood Hits	305	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

GRIPE_HUMAN
NC score	0.453460 (rank : 9)	θ value	2.0648e-12 (rank : 9)
Query Neighborhood Hits	305	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
NC score	0.441591 (rank : 10)	θ value	1.74796e-11 (rank : 10)
Query Neighborhood Hits	305	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
NC score	0.431781 (rank : 11)	θ value	7.34386e-10 (rank : 11)
Query Neighborhood Hits	305	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
NC score	0.411422 (rank : 12)	θ value	2.13673e-09 (rank : 12)
Query Neighborhood Hits	305	Target Neighborhood Hits	48	Shared Neighborhood Hits	15
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

SHAN2_HUMAN
NC score	0.154358 (rank : 13)	θ value	0.00665767 (rank : 17)
Query Neighborhood Hits	305	Target Neighborhood Hits	346	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
NC score	0.139095 (rank : 14)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	305	Target Neighborhood Hits	446	Shared Neighborhood Hits	67
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

APBA3_MOUSE
NC score	0.138929 (rank : 15)	θ value	0.0113563 (rank : 19)
Query Neighborhood Hits	305	Target Neighborhood Hits	174	Shared Neighborhood Hits	42
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA2_MOUSE
NC score	0.138755 (rank : 16)	θ value	0.0252991 (rank : 26)
Query Neighborhood Hits	305	Target Neighborhood Hits	219	Shared Neighborhood Hits	44
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.138626 (rank : 17)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	305	Target Neighborhood Hits	220	Shared Neighborhood Hits	44
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
NC score	0.125528 (rank : 18)	θ value	0.0736092 (rank : 34)
Query Neighborhood Hits	305	Target Neighborhood Hits	201	Shared Neighborhood Hits	44
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

APBA1_HUMAN
NC score	0.122378 (rank : 19)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	305	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

SHAN1_HUMAN
NC score	0.109886 (rank : 20)	θ value	0.000461057 (rank : 15)
Query Neighborhood Hits	305	Target Neighborhood Hits	1041	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

WIRE_MOUSE
NC score	0.109357 (rank : 21)	θ value	0.00020696 (rank : 13)
Query Neighborhood Hits	305	Target Neighborhood Hits	310	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WIRE_HUMAN
NC score	0.107472 (rank : 22)	θ value	0.00035302 (rank : 14)
Query Neighborhood Hits	305	Target Neighborhood Hits	329	Shared Neighborhood Hits	57
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

NHERF_HUMAN
NC score	0.101276 (rank : 23)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	305	Target Neighborhood Hits	190	Shared Neighborhood Hits	40
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
NC score	0.094146 (rank : 24)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	305	Target Neighborhood Hits	195	Shared Neighborhood Hits	41
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

USH1C_MOUSE
NC score	0.091320 (rank : 25)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	305	Target Neighborhood Hits	557	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

USH1C_HUMAN
NC score	0.087365 (rank : 26)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	305	Target Neighborhood Hits	327	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

BSN_MOUSE
NC score	0.084568 (rank : 27)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	305	Target Neighborhood Hits	2057	Shared Neighborhood Hits	208
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SRRM1_MOUSE
NC score	0.080957 (rank : 28)	θ value	0.0563607 (rank : 33)
Query Neighborhood Hits	305	Target Neighborhood Hits	966	Shared Neighborhood Hits	127
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PDZD3_MOUSE
NC score	0.080243 (rank : 29)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	305	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

SPT5H_MOUSE
NC score	0.076322 (rank : 30)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	305	Target Neighborhood Hits	437	Shared Neighborhood Hits	74
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

NHRF2_HUMAN
NC score	0.076227 (rank : 31)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	305	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

SPT5H_HUMAN
NC score	0.076200 (rank : 32)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	305	Target Neighborhood Hits	436	Shared Neighborhood Hits	75
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

NACAM_MOUSE
NC score	0.075864 (rank : 33)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	305	Target Neighborhood Hits	1866	Shared Neighborhood Hits	165
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SRRM2_MOUSE
NC score	0.074905 (rank : 34)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	305	Target Neighborhood Hits	1470	Shared Neighborhood Hits	155
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PARD3_MOUSE
NC score	0.073442 (rank : 35)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	305	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

TARSH_HUMAN
NC score	0.072925 (rank : 36)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	305	Target Neighborhood Hits	768	Shared Neighborhood Hits	112
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CBP_HUMAN
NC score	0.072836 (rank : 37)	θ value	0.00102713 (rank : 16)
Query Neighborhood Hits	305	Target Neighborhood Hits	941	Shared Neighborhood Hits	103
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PCLO_MOUSE
NC score	0.072381 (rank : 38)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	305	Target Neighborhood Hits	2275	Shared Neighborhood Hits	195
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CBP_MOUSE
NC score	0.072149 (rank : 39)	θ value	0.0736092 (rank : 35)
Query Neighborhood Hits	305	Target Neighborhood Hits	1051	Shared Neighborhood Hits	126
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SRRM2_HUMAN
NC score	0.072101 (rank : 40)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	305	Target Neighborhood Hits	1296	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CN032_HUMAN
NC score	0.071887 (rank : 41)	θ value	0.0193708 (rank : 24)
Query Neighborhood Hits	305	Target Neighborhood Hits	267	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

PCLO_HUMAN
NC score	0.071162 (rank : 42)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	305	Target Neighborhood Hits	2046	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

NHRF2_MOUSE
NC score	0.068119 (rank : 43)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	305	Target Neighborhood Hits	194	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PDZD1_HUMAN
NC score	0.068074 (rank : 44)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	305	Target Neighborhood Hits	190	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

BCL9_HUMAN
NC score	0.067884 (rank : 45)	θ value	0.813845 (rank : 82)
Query Neighborhood Hits	305	Target Neighborhood Hits	1008	Shared Neighborhood Hits	123
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BSN_HUMAN
NC score	0.067559 (rank : 46)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	305	Target Neighborhood Hits	1537	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SRRM1_HUMAN
NC score	0.067111 (rank : 47)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	305	Target Neighborhood Hits	690	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MDC1_HUMAN
NC score	0.066118 (rank : 48)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	305	Target Neighborhood Hits	1446	Shared Neighborhood Hits	148
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NCOA6_HUMAN
NC score	0.065988 (rank : 49)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	305	Target Neighborhood Hits	1202	Shared Neighborhood Hits	149
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MUC1_HUMAN
NC score	0.065352 (rank : 50)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	305	Target Neighborhood Hits	975	Shared Neighborhood Hits	120
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MDC1_MOUSE
NC score	0.063599 (rank : 51)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	305	Target Neighborhood Hits	998	Shared Neighborhood Hits	115
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PARD3_HUMAN
NC score	0.063559 (rank : 52)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	305	Target Neighborhood Hits	312	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PRRT3_HUMAN
NC score	0.063301 (rank : 53)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	305	Target Neighborhood Hits	998	Shared Neighborhood Hits	134
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ARHGB_HUMAN
NC score	0.063300 (rank : 54)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	305	Target Neighborhood Hits	375	Shared Neighborhood Hits	52
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

WHRN_MOUSE
NC score	0.062944 (rank : 55)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	305	Target Neighborhood Hits	412	Shared Neighborhood Hits	75
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

K1802_MOUSE
NC score	0.061976 (rank : 56)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	305	Target Neighborhood Hits	1596	Shared Neighborhood Hits	141
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

OGFR_HUMAN
NC score	0.060722 (rank : 57)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	305	Target Neighborhood Hits	1582	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PI5PA_HUMAN
NC score	0.060127 (rank : 58)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	305	Target Neighborhood Hits	749	Shared Neighborhood Hits	106
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MUC7_HUMAN
NC score	0.059750 (rank : 59)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	305	Target Neighborhood Hits	538	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MAGI1_HUMAN
NC score	0.059654 (rank : 60)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	305	Target Neighborhood Hits	388	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

SON_HUMAN
NC score	0.058983 (rank : 61)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	305	Target Neighborhood Hits	1568	Shared Neighborhood Hits	152
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WHRN_HUMAN
NC score	0.058534 (rank : 62)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	305	Target Neighborhood Hits	325	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

SYP2L_HUMAN
NC score	0.058461 (rank : 63)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	305	Target Neighborhood Hits	400	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TAB3_MOUSE
NC score	0.057597 (rank : 64)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	305	Target Neighborhood Hits	273	Shared Neighborhood Hits	58
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

SELPL_MOUSE
NC score	0.057467 (rank : 65)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	305	Target Neighborhood Hits	588	Shared Neighborhood Hits	90
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

MAGI1_MOUSE
NC score	0.056420 (rank : 66)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	305	Target Neighborhood Hits	403	Shared Neighborhood Hits	58
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PKHA4_HUMAN
NC score	0.056296 (rank : 67)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	305	Target Neighborhood Hits	283	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

TAB3_HUMAN
NC score	0.055885 (rank : 68)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	305	Target Neighborhood Hits	168	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

MYOC_HUMAN
NC score	0.055389 (rank : 69)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	305	Target Neighborhood Hits	489	Shared Neighborhood Hits	40
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

TARA_HUMAN
NC score	0.055049 (rank : 70)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	305	Target Neighborhood Hits	1626	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PKHA4_MOUSE
NC score	0.054677 (rank : 71)	θ value	0.0736092 (rank : 36)
Query Neighborhood Hits	305	Target Neighborhood Hits	202	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

BCL9_MOUSE
NC score	0.054599 (rank : 72)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	305	Target Neighborhood Hits	770	Shared Neighborhood Hits	107
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MLL2_HUMAN
NC score	0.053119 (rank : 73)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	305	Target Neighborhood Hits	1788	Shared Neighborhood Hits	144
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.052968 (rank : 74)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	305	Target Neighborhood Hits	1644	Shared Neighborhood Hits	150
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CN032_MOUSE
NC score	0.052051 (rank : 75)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	305	Target Neighborhood Hits	233	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

EP300_HUMAN
NC score	0.051582 (rank : 76)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	305	Target Neighborhood Hits	821	Shared Neighborhood Hits	92
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

RGS3_MOUSE
NC score	0.051551 (rank : 77)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	305	Target Neighborhood Hits	1621	Shared Neighborhood Hits	176
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PDZD1_MOUSE
NC score	0.051390 (rank : 78)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	305	Target Neighborhood Hits	191	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PO121_HUMAN
NC score	0.051144 (rank : 79)	θ value	0.0563607 (rank : 32)
Query Neighborhood Hits	305	Target Neighborhood Hits	344	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

NCOA6_MOUSE
NC score	0.051137 (rank : 80)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	305	Target Neighborhood Hits	1076	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PDZD3_HUMAN
NC score	0.050755 (rank : 81)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	305	Target Neighborhood Hits	180	Shared Neighborhood Hits	38
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PRB3_HUMAN
NC score	0.050706 (rank : 82)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	305	Target Neighborhood Hits	318	Shared Neighborhood Hits	45
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRR12_HUMAN
NC score	0.050657 (rank : 83)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	305	Target Neighborhood Hits	460	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

MLL3_MOUSE
NC score	0.050543 (rank : 84)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	305	Target Neighborhood Hits	1399	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PRR8_HUMAN
NC score	0.050182 (rank : 85)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	305	Target Neighborhood Hits	217	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

SF3B1_HUMAN
NC score	0.047739 (rank : 86)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	305	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

RPB1_MOUSE
NC score	0.047662 (rank : 87)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	305	Target Neighborhood Hits	363	Shared Neighborhood Hits	39
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SF3B1_MOUSE
NC score	0.047631 (rank : 88)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	305	Target Neighborhood Hits	352	Shared Neighborhood Hits	57
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

WASL_MOUSE
NC score	0.047334 (rank : 89)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	305	Target Neighborhood Hits	339	Shared Neighborhood Hits	55
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RAPH1_HUMAN
NC score	0.047321 (rank : 90)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	305	Target Neighborhood Hits	593	Shared Neighborhood Hits	75
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

WASL_HUMAN
NC score	0.046962 (rank : 91)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	305	Target Neighborhood Hits	312	Shared Neighborhood Hits	48
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RPB1_HUMAN
NC score	0.046736 (rank : 92)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	305	Target Neighborhood Hits	362	Shared Neighborhood Hits	39
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ARI1A_HUMAN
NC score	0.046559 (rank : 93)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	305	Target Neighborhood Hits	787	Shared Neighborhood Hits	87
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAG3_MOUSE
NC score	0.046039 (rank : 94)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	305	Target Neighborhood Hits	513	Shared Neighborhood Hits	87
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

LAP4_MOUSE
NC score	0.045619 (rank : 95)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	305	Target Neighborhood Hits	590	Shared Neighborhood Hits	56
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MPDZ_HUMAN
NC score	0.045068 (rank : 96)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	305	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

CSF1_HUMAN
NC score	0.045032 (rank : 97)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	305	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

PDC6I_MOUSE
NC score	0.045015 (rank : 98)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	305	Target Neighborhood Hits	275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

GPTC8_HUMAN
NC score	0.044913 (rank : 99)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	305	Target Neighborhood Hits	366	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

CECR2_HUMAN
NC score	0.044641 (rank : 100)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	305	Target Neighborhood Hits	543	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

SNPC4_HUMAN
NC score	0.044198 (rank : 101)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	305	Target Neighborhood Hits	589	Shared Neighborhood Hits	98
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

LR37A_HUMAN
NC score	0.043554 (rank : 102)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	305	Target Neighborhood Hits	720	Shared Neighborhood Hits	68
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

TFG_HUMAN
NC score	0.043460 (rank : 103)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	305	Target Neighborhood Hits	122	Shared Neighborhood Hits	19
SwissProt Accessions	Q92734, Q15656	Gene names	TFG
Domain Architecture
Description	Protein TFG (TRK-fused gene protein).

MPDZ_MOUSE
NC score	0.043356 (rank : 104)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	305	Target Neighborhood Hits	298	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

CARD6_HUMAN
NC score	0.043296 (rank : 105)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	305	Target Neighborhood Hits	145	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

PHLB1_HUMAN
NC score	0.042827 (rank : 106)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	305	Target Neighborhood Hits	1038	Shared Neighborhood Hits	107
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PI5PA_MOUSE
NC score	0.042434 (rank : 107)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	305	Target Neighborhood Hits	331	Shared Neighborhood Hits	56
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

DIDO1_HUMAN
NC score	0.042121 (rank : 108)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	305	Target Neighborhood Hits	960	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ATN1_HUMAN
NC score	0.041869 (rank : 109)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	305	Target Neighborhood Hits	676	Shared Neighborhood Hits	82
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

PRG4_HUMAN
NC score	0.041848 (rank : 110)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	305	Target Neighborhood Hits	764	Shared Neighborhood Hits	80
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SYNJ1_MOUSE
NC score	0.041456 (rank : 111)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	305	Target Neighborhood Hits	516	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_HUMAN
NC score	0.040797 (rank : 112)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	305	Target Neighborhood Hits	498	Shared Neighborhood Hits	74
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

NFAC2_MOUSE
NC score	0.040712 (rank : 113)	θ value	0.0252991 (rank : 27)
Query Neighborhood Hits	305	Target Neighborhood Hits	98	Shared Neighborhood Hits	20
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

K1802_HUMAN
NC score	0.040414 (rank : 114)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	305	Target Neighborhood Hits	1378	Shared Neighborhood Hits	126
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LAP4_HUMAN
NC score	0.040347 (rank : 115)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	305	Target Neighborhood Hits	608	Shared Neighborhood Hits	53
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

SGIP1_MOUSE
NC score	0.039904 (rank : 116)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	305	Target Neighborhood Hits	180	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

PHLB1_MOUSE
NC score	0.039745 (rank : 117)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	305	Target Neighborhood Hits	678	Shared Neighborhood Hits	84
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CIC_HUMAN
NC score	0.039121 (rank : 118)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	305	Target Neighborhood Hits	992	Shared Neighborhood Hits	121
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RD23B_MOUSE
NC score	0.039039 (rank : 119)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	305	Target Neighborhood Hits	189	Shared Neighborhood Hits	26
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

TCRG1_HUMAN
NC score	0.038715 (rank : 120)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	305	Target Neighborhood Hits	929	Shared Neighborhood Hits	76
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

MNT_MOUSE
NC score	0.038415 (rank : 121)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	305	Target Neighborhood Hits	432	Shared Neighborhood Hits	55
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MINT_MOUSE
NC score	0.038234 (rank : 122)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	305	Target Neighborhood Hits	1514	Shared Neighborhood Hits	135
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TCRG1_MOUSE
NC score	0.038104 (rank : 123)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	305	Target Neighborhood Hits	947	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

WDR46_MOUSE
NC score	0.038096 (rank : 124)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	305	Target Neighborhood Hits	243	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

RUFY1_HUMAN
NC score	0.037380 (rank : 125)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	305	Target Neighborhood Hits	848	Shared Neighborhood Hits	56
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

MUC2_HUMAN
NC score	0.037318 (rank : 126)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	305	Target Neighborhood Hits	906	Shared Neighborhood Hits	72
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

BRD4_MOUSE
NC score	0.036580 (rank : 127)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	305	Target Neighborhood Hits	845	Shared Neighborhood Hits	94
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

TTLL5_MOUSE
NC score	0.036196 (rank : 128)	θ value	0.0148317 (rank : 23)
Query Neighborhood Hits	305	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

BLNK_MOUSE
NC score	0.035452 (rank : 129)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	305	Target Neighborhood Hits	296	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

PCQAP_HUMAN
NC score	0.035004 (rank : 130)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	305	Target Neighborhood Hits	549	Shared Neighborhood Hits	71
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PHC2_HUMAN
NC score	0.034915 (rank : 131)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	305	Target Neighborhood Hits	388	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

EP15R_MOUSE
NC score	0.034394 (rank : 132)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	305	Target Neighborhood Hits	1135	Shared Neighborhood Hits	68
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

CNOT3_MOUSE
NC score	0.034174 (rank : 133)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	305	Target Neighborhood Hits	504	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SYN1_HUMAN
NC score	0.033717 (rank : 134)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	305	Target Neighborhood Hits	419	Shared Neighborhood Hits	54
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

BASP_HUMAN
NC score	0.033701 (rank : 135)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	305	Target Neighborhood Hits	321	Shared Neighborhood Hits	38
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TCOF_HUMAN
NC score	0.033669 (rank : 136)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	305	Target Neighborhood Hits	543	Shared Neighborhood Hits	59
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CS007_MOUSE
NC score	0.032560 (rank : 137)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	305	Target Neighborhood Hits	464	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DCP1B_HUMAN
NC score	0.032510 (rank : 138)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	305	Target Neighborhood Hits	118	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

GOGA3_MOUSE
NC score	0.032422 (rank : 139)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	305	Target Neighborhood Hits	1437	Shared Neighborhood Hits	69
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

ENAH_HUMAN
NC score	0.031894 (rank : 140)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	305	Target Neighborhood Hits	784	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FXL19_MOUSE
NC score	0.031885 (rank : 141)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	305	Target Neighborhood Hits	217	Shared Neighborhood Hits	33
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

BRD8_MOUSE
NC score	0.031477 (rank : 142)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	305	Target Neighborhood Hits	422	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

TPR_HUMAN
NC score	0.031472 (rank : 143)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	305	Target Neighborhood Hits	1921	Shared Neighborhood Hits	100
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SGIP1_HUMAN
NC score	0.031454 (rank : 144)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	305	Target Neighborhood Hits	198	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

MYO15_HUMAN
NC score	0.031353 (rank : 145)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	305	Target Neighborhood Hits	671	Shared Neighborhood Hits	111
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CT174_HUMAN
NC score	0.031194 (rank : 146)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	305	Target Neighborhood Hits	181	Shared Neighborhood Hits	33
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

NFAC4_HUMAN
NC score	0.031188 (rank : 147)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	305	Target Neighborhood Hits	165	Shared Neighborhood Hits	21
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

G6B_HUMAN
NC score	0.031092 (rank : 148)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	305	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	O95866, Q96A86, Q96A87, Q96A88, Q96A89, Q96A90, Q96A91	Gene names	G6B, C6orf25
Domain Architecture	No domain graphic available
Description	G6b protein precursor.

MYH9_MOUSE
NC score	0.030842 (rank : 149)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	305	Target Neighborhood Hits	1829	Shared Neighborhood Hits	83
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

GRAP1_HUMAN
NC score	0.030664 (rank : 150)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	305	Target Neighborhood Hits	944	Shared Neighborhood Hits	53
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

MY18A_MOUSE
NC score	0.030590 (rank : 151)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	305	Target Neighborhood Hits	1989	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

GOGA3_HUMAN
NC score	0.030560 (rank : 152)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	305	Target Neighborhood Hits	1317	Shared Neighborhood Hits	80
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

NAF1_MOUSE
NC score	0.030394 (rank : 153)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	305	Target Neighborhood Hits	852	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

GRAP1_MOUSE
NC score	0.030169 (rank : 154)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	305	Target Neighborhood Hits	1234	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

NFAC2_HUMAN
NC score	0.030153 (rank : 155)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	305	Target Neighborhood Hits	101	Shared Neighborhood Hits	23
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

JADE2_MOUSE
NC score	0.030116 (rank : 156)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	305	Target Neighborhood Hits	560	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MYH9_HUMAN
NC score	0.030044 (rank : 157)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	305	Target Neighborhood Hits	1762	Shared Neighborhood Hits	76
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SC24A_MOUSE
NC score	0.029467 (rank : 158)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	305	Target Neighborhood Hits	394	Shared Neighborhood Hits	66
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

TUFT1_HUMAN
NC score	0.029266 (rank : 159)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	305	Target Neighborhood Hits	686	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

EP15R_HUMAN
NC score	0.028915 (rank : 160)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	305	Target Neighborhood Hits	1083	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

RHG25_HUMAN
NC score	0.028737 (rank : 161)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	305	Target Neighborhood Hits	550	Shared Neighborhood Hits	47
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

HRX_HUMAN
NC score	0.028659 (rank : 162)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	305	Target Neighborhood Hits	825	Shared Neighborhood Hits	67
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MYH10_HUMAN
NC score	0.028599 (rank : 163)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	305	Target Neighborhood Hits	1620	Shared Neighborhood Hits	80
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.028362 (rank : 164)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	305	Target Neighborhood Hits	1612	Shared Neighborhood Hits	81
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_MOUSE
NC score	0.028278 (rank : 165)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	305	Target Neighborhood Hits	1777	Shared Neighborhood Hits	74
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

AZI1_HUMAN
NC score	0.028112 (rank : 166)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	305	Target Neighborhood Hits	1000	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

NUMA1_HUMAN
NC score	0.028096 (rank : 167)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	305	Target Neighborhood Hits	1523	Shared Neighborhood Hits	78
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PTN13_HUMAN
NC score	0.028050 (rank : 168)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	305	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

WDR46_HUMAN
NC score	0.027999 (rank : 169)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	305	Target Neighborhood Hits	147	Shared Neighborhood Hits	10
SwissProt Accessions	O15213, Q5STK5	Gene names	WDR46, BING4, C6orf11
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

K1688_HUMAN
NC score	0.027708 (rank : 170)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	305	Target Neighborhood Hits	217	Shared Neighborhood Hits	35
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

R3HD1_HUMAN
NC score	0.027667 (rank : 171)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	305	Target Neighborhood Hits	203	Shared Neighborhood Hits	41
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

MY18A_HUMAN
NC score	0.027591 (rank : 172)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	305	Target Neighborhood Hits	1929	Shared Neighborhood Hits	106
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TACC3_HUMAN
NC score	0.027538 (rank : 173)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	305	Target Neighborhood Hits	779	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

ALMS1_HUMAN
NC score	0.027462 (rank : 174)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	305	Target Neighborhood Hits	356	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

MYH11_HUMAN
NC score	0.027203 (rank : 175)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	305	Target Neighborhood Hits	1806	Shared Neighborhood Hits	79
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CYTSA_HUMAN
NC score	0.027157 (rank : 176)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	305	Target Neighborhood Hits	1138	Shared Neighborhood Hits	72
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

MAST4_HUMAN
NC score	0.026968 (rank : 177)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	305	Target Neighborhood Hits	1804	Shared Neighborhood Hits	150
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

IQEC2_MOUSE
NC score	0.026341 (rank : 178)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	305	Target Neighborhood Hits	417	Shared Neighborhood Hits	49
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.026211 (rank : 179)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	305	Target Neighborhood Hits	403	Shared Neighborhood Hits	49
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

NEMO_MOUSE
NC score	0.025642 (rank : 180)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	305	Target Neighborhood Hits	658	Shared Neighborhood Hits	55
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

TERF2_HUMAN
NC score	0.025349 (rank : 181)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	305	Target Neighborhood Hits	102	Shared Neighborhood Hits	16
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

ASTL_HUMAN
NC score	0.025120 (rank : 182)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	305	Target Neighborhood Hits	252	Shared Neighborhood Hits	42
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

PYGO2_HUMAN
NC score	0.025057 (rank : 183)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	305	Target Neighborhood Hits	189	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

DIAP1_HUMAN
NC score	0.025000 (rank : 184)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	305	Target Neighborhood Hits	784	Shared Neighborhood Hits	75
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

MKL1_HUMAN
NC score	0.024689 (rank : 185)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	305	Target Neighborhood Hits	232	Shared Neighborhood Hits	32
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

FXL19_HUMAN
NC score	0.024478 (rank : 186)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	305	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

DOK7_MOUSE
NC score	0.024469 (rank : 187)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	305	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

HCN2_MOUSE
NC score	0.024278 (rank : 188)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	305	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

CSKI1_MOUSE
NC score	0.023899 (rank : 189)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	305	Target Neighborhood Hits	1031	Shared Neighborhood Hits	110
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TRIPB_HUMAN
NC score	0.023837 (rank : 190)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	305	Target Neighborhood Hits	1587	Shared Neighborhood Hits	76
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

PHC2_MOUSE
NC score	0.023798 (rank : 191)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	305	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

MAGC1_HUMAN
NC score	0.023433 (rank : 192)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	305	Target Neighborhood Hits	431	Shared Neighborhood Hits	49
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

ATX2_HUMAN
NC score	0.023395 (rank : 193)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	305	Target Neighborhood Hits	375	Shared Neighborhood Hits	48
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

PTN23_MOUSE
NC score	0.023298 (rank : 194)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	305	Target Neighborhood Hits	726	Shared Neighborhood Hits	89
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

GON4L_HUMAN
NC score	0.022998 (rank : 195)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	305	Target Neighborhood Hits	555	Shared Neighborhood Hits	64
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MYO5A_HUMAN
NC score	0.022919 (rank : 196)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	305	Target Neighborhood Hits	1092	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO9B_HUMAN
NC score	0.022874 (rank : 197)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	305	Target Neighborhood Hits	641	Shared Neighborhood Hits	77
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SMCA4_HUMAN
NC score	0.022596 (rank : 198)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	305	Target Neighborhood Hits	597	Shared Neighborhood Hits	60
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

DOCK4_MOUSE
NC score	0.022191 (rank : 199)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	305	Target Neighborhood Hits	210	Shared Neighborhood Hits	41
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

CING_MOUSE
NC score	0.022059 (rank : 200)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	305	Target Neighborhood Hits	1432	Shared Neighborhood Hits	73
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CN065_HUMAN
NC score	0.021937 (rank : 201)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	305	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N9R9	Gene names	C14orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf65.

BCLF1_MOUSE
NC score	0.021872 (rank : 202)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	305	Target Neighborhood Hits	303	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

CENPE_HUMAN
NC score	0.021764 (rank : 203)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	305	Target Neighborhood Hits	2060	Shared Neighborhood Hits	80
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

FMNL_HUMAN
NC score	0.021675 (rank : 204)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	305	Target Neighborhood Hits	529	Shared Neighborhood Hits	65
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

MYO5A_MOUSE
NC score	0.021479 (rank : 205)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	305	Target Neighborhood Hits	1117	Shared Neighborhood Hits	61
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MAST2_HUMAN
NC score	0.021262 (rank : 206)	θ value	0.0148317 (rank : 21)
Query Neighborhood Hits	305	Target Neighborhood Hits	1189	Shared Neighborhood Hits	79
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

BPAEA_MOUSE
NC score	0.020874 (rank : 207)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	305	Target Neighborhood Hits	1480	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

JIP2_HUMAN
NC score	0.020801 (rank : 208)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	305	Target Neighborhood Hits	288	Shared Neighborhood Hits	30
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

MPP10_MOUSE
NC score	0.020745 (rank : 209)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	305	Target Neighborhood Hits	251	Shared Neighborhood Hits	21
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

RIN3_HUMAN
NC score	0.020015 (rank : 210)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	305	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

BCLF1_HUMAN
NC score	0.019927 (rank : 211)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	305	Target Neighborhood Hits	298	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

FOSB_HUMAN
NC score	0.019916 (rank : 212)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	305	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

MYH13_HUMAN
NC score	0.019810 (rank : 213)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	305	Target Neighborhood Hits	1504	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

IF4G1_HUMAN
NC score	0.019572 (rank : 214)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	305	Target Neighborhood Hits	347	Shared Neighborhood Hits	49
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

RNPC1_MOUSE
NC score	0.019221 (rank : 215)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	305	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	Q62176, Q922Z2	Gene names	Rnpc1, Seb4, Seb4l
Domain Architecture
Description	RNA-binding region-containing protein 1 (ssDNA-binding protein SEB4).

IF35_MOUSE
NC score	0.019198 (rank : 216)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	305	Target Neighborhood Hits	210	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

PHAR2_HUMAN
NC score	0.019189 (rank : 217)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	305	Target Neighborhood Hits	208	Shared Neighborhood Hits	23
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

LIPB2_HUMAN
NC score	0.019120 (rank : 218)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	305	Target Neighborhood Hits	599	Shared Neighborhood Hits	52
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LMNB2_MOUSE
NC score	0.019077 (rank : 219)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	305	Target Neighborhood Hits	674	Shared Neighborhood Hits	45
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

MAST2_MOUSE
NC score	0.019034 (rank : 220)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	305	Target Neighborhood Hits	1110	Shared Neighborhood Hits	69
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

BEGIN_MOUSE
NC score	0.018549 (rank : 221)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	305	Target Neighborhood Hits	383	Shared Neighborhood Hits	39
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

IASPP_HUMAN
NC score	0.018402 (rank : 222)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	305	Target Neighborhood Hits	688	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LDB3_HUMAN
NC score	0.018301 (rank : 223)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	305	Target Neighborhood Hits	497	Shared Neighborhood Hits	62
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

RNPS1_HUMAN
NC score	0.017899 (rank : 224)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	305	Target Neighborhood Hits	285	Shared Neighborhood Hits	15
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.017899 (rank : 225)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	305	Target Neighborhood Hits	285	Shared Neighborhood Hits	15
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

FBSH_MOUSE
NC score	0.017339 (rank : 226)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	305	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R089	Gene names	Fbs1, Fbs
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

CTGE5_HUMAN
NC score	0.017237 (rank : 227)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	305	Target Neighborhood Hits	800	Shared Neighborhood Hits	46
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

GCNL2_HUMAN
NC score	0.017149 (rank : 228)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	305	Target Neighborhood Hits	159	Shared Neighborhood Hits	28
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

TLN1_MOUSE
NC score	0.016990 (rank : 229)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	305	Target Neighborhood Hits	213	Shared Neighborhood Hits	16
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

LMNB2_HUMAN
NC score	0.016749 (rank : 230)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	305	Target Neighborhood Hits	723	Shared Neighborhood Hits	49
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

FOSB_MOUSE
NC score	0.016666 (rank : 231)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	305	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

DDEF1_MOUSE
NC score	0.016399 (rank : 232)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	305	Target Neighborhood Hits	592	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

HXA3_HUMAN
NC score	0.016012 (rank : 233)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	305	Target Neighborhood Hits	535	Shared Neighborhood Hits	40
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

PO6F2_HUMAN
NC score	0.015984 (rank : 234)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	305	Target Neighborhood Hits	618	Shared Neighborhood Hits	47
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PRG3_MOUSE
NC score	0.015930 (rank : 235)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	305	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

HXA3_MOUSE
NC score	0.015814 (rank : 236)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	305	Target Neighborhood Hits	558	Shared Neighborhood Hits	43
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

MAST1_HUMAN
NC score	0.015540 (rank : 237)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	305	Target Neighborhood Hits	1146	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ZEP1_HUMAN
NC score	0.015537 (rank : 238)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	305	Target Neighborhood Hits	1036	Shared Neighborhood Hits	68
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

CSKI2_HUMAN
NC score	0.015454 (rank : 239)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	305	Target Neighborhood Hits	747	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

RNPC1_HUMAN
NC score	0.015375 (rank : 240)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	305	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0Z9, Q15350, Q15351, Q9BYK3, Q9BYK4	Gene names	RNPC1, SEB4
Domain Architecture
Description	RNA-binding region-containing protein 1 (HSRNASEB) (ssDNA-binding protein SEB4) (CLL-associated antigen KW-5).

AFF4_HUMAN
NC score	0.015356 (rank : 241)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	305	Target Neighborhood Hits	611	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

FA5_HUMAN
NC score	0.015264 (rank : 242)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	305	Target Neighborhood Hits	172	Shared Neighborhood Hits	21
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

MAST1_MOUSE
NC score	0.015121 (rank : 243)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	305	Target Neighborhood Hits	1123	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

LSD1_MOUSE
NC score	0.014447 (rank : 244)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	305	Target Neighborhood Hits	224	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

B4GN3_HUMAN
NC score	0.013949 (rank : 245)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	305	Target Neighborhood Hits	128	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

TNNI2_MOUSE
NC score	0.013618 (rank : 246)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	305	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	P13412	Gene names	Tnni2
Domain Architecture
Description	Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).

AAK1_MOUSE
NC score	0.013583 (rank : 247)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	305	Target Neighborhood Hits	1051	Shared Neighborhood Hits	76
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

RP3A_HUMAN
NC score	0.013504 (rank : 248)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	305	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

MYOM1_MOUSE
NC score	0.013449 (rank : 249)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	305	Target Neighborhood Hits	415	Shared Neighborhood Hits	14
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

LMD1_HUMAN
NC score	0.013444 (rank : 250)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	305	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

HXB9_MOUSE
NC score	0.013280 (rank : 251)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	305	Target Neighborhood Hits	344	Shared Neighborhood Hits	14
SwissProt Accessions	P20615	Gene names	Hoxb9, Hox-2.5, Hoxb-9
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2.5).

GP156_HUMAN
NC score	0.013274 (rank : 252)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	305	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

ZEP1_MOUSE
NC score	0.013222 (rank : 253)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	305	Target Neighborhood Hits	1063	Shared Neighborhood Hits	61
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

SIN3A_HUMAN
NC score	0.013048 (rank : 254)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	305	Target Neighborhood Hits	180	Shared Neighborhood Hits	32
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SF3B4_HUMAN
NC score	0.012883 (rank : 255)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	305	Target Neighborhood Hits	445	Shared Neighborhood Hits	40
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

U520_HUMAN
NC score	0.012692 (rank : 256)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	305	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CCDC9_HUMAN
NC score	0.012532 (rank : 257)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	305	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

FA53B_MOUSE
NC score	0.012419 (rank : 258)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	305	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGR5, Q3UGW1, Q8BI13	Gene names	Fam53b
Domain Architecture	No domain graphic available
Description	Protein FAM53B.

TLN1_HUMAN
NC score	0.012346 (rank : 259)	θ value	4.03905 (rank : 216)
Query Neighborhood Hits	305	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

HXB9_HUMAN
NC score	0.011647 (rank : 260)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	305	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	P17482, Q9H1I1	Gene names	HOXB9, HOX2E
Domain Architecture
Description	Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5).

HDAC4_HUMAN
NC score	0.011371 (rank : 261)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	305	Target Neighborhood Hits	390	Shared Neighborhood Hits	33
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

TNNI2_HUMAN
NC score	0.011130 (rank : 262)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	305	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	P48788	Gene names	TNNI2
Domain Architecture
Description	Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).

DYN1_HUMAN
NC score	0.010979 (rank : 263)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	305	Target Neighborhood Hits	216	Shared Neighborhood Hits	40
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

RX_MOUSE
NC score	0.010748 (rank : 264)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	305	Target Neighborhood Hits	429	Shared Neighborhood Hits	18
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

KCNH3_MOUSE
NC score	0.010683 (rank : 265)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	305	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

PHF8_HUMAN
NC score	0.010459 (rank : 266)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	305	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

ANX11_MOUSE
NC score	0.010403 (rank : 267)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	305	Target Neighborhood Hits	200	Shared Neighborhood Hits	24
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

DPOE1_HUMAN
NC score	0.010267 (rank : 268)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	305	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

GPSM1_MOUSE
NC score	0.010107 (rank : 269)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	305	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q6IR34, Q61366, Q8BUK4, Q8BX78, Q8R0R9	Gene names	Gpsm1, Ags3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

STK10_HUMAN
NC score	0.010080 (rank : 270)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	305	Target Neighborhood Hits	1921	Shared Neighborhood Hits	95
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

F125B_HUMAN
NC score	0.009943 (rank : 271)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	305	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7P6, Q8N6S7	Gene names	FAM125B, C9orf28
Domain Architecture	No domain graphic available
Description	Protein FAM125B.

RHG06_HUMAN
NC score	0.009934 (rank : 272)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	305	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

ANX11_HUMAN
NC score	0.009882 (rank : 273)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	305	Target Neighborhood Hits	192	Shared Neighborhood Hits	28
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

LRC50_HUMAN
NC score	0.009813 (rank : 274)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	305	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

SSH1_MOUSE
NC score	0.009783 (rank : 275)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	305	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

LRP3_HUMAN
NC score	0.009754 (rank : 276)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	305	Target Neighborhood Hits	280	Shared Neighborhood Hits	18
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

NBEA_MOUSE
NC score	0.009444 (rank : 277)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	305	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

IMPG1_HUMAN
NC score	0.009073 (rank : 278)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	305	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

CAMKV_HUMAN
NC score	0.009027 (rank : 279)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	305	Target Neighborhood Hits	1084	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

HXC4_MOUSE
NC score	0.008657 (rank : 280)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	305	Target Neighborhood Hits	365	Shared Neighborhood Hits	17
SwissProt Accessions	Q08624	Gene names	Hoxc4, Hox-3.5, Hoxc-4
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3.5).

TITIN_HUMAN
NC score	0.008652 (rank : 281)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	305	Target Neighborhood Hits	2923	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CLIC6_HUMAN
NC score	0.008553 (rank : 282)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	305	Target Neighborhood Hits	289	Shared Neighborhood Hits	26
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CO5A3_HUMAN
NC score	0.008166 (rank : 283)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	305	Target Neighborhood Hits	433	Shared Neighborhood Hits	30
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

ANR25_HUMAN
NC score	0.008146 (rank : 284)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	305	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ZDHC5_MOUSE
NC score	0.008097 (rank : 285)	θ value	4.03905 (rank : 218)
Query Neighborhood Hits	305	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

SOCS6_MOUSE
NC score	0.008032 (rank : 286)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	305	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLY0, Q9D2A0	Gene names	Socs6, Cis4, Cish4, Socs4
Domain Architecture
Description	Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor of cytokine signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4) (CIS-4).

WWOX_HUMAN
NC score	0.007617 (rank : 287)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	305	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZC7, Q5MYT5, Q96KM3, Q96RF2, Q9BTT8, Q9NPC9, Q9NRF4, Q9NRF5, Q9NRF6, Q9NRK1, Q9NZC5	Gene names	WWOX, FOR, WOX1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase).

WWOX_MOUSE
NC score	0.007477 (rank : 288)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	305	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WL8, Q8C8J6, Q920Y2, Q9D2B3, Q9D339, Q9JLF5	Gene names	Wwox, Wox1
Domain Architecture	No domain graphic available
Description	WW domain-containing oxidoreductase (EC 1.1.1.-).

WNK1_HUMAN
NC score	0.007431 (rank : 289)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	305	Target Neighborhood Hits	1158	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

PRP4B_MOUSE
NC score	0.007162 (rank : 290)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	305	Target Neighborhood Hits	1040	Shared Neighborhood Hits	39
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

ANKS6_MOUSE
NC score	0.007090 (rank : 291)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	305	Target Neighborhood Hits	435	Shared Neighborhood Hits	28
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

RUSC1_MOUSE
NC score	0.006826 (rank : 292)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	305	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

HXC4_HUMAN
NC score	0.006769 (rank : 293)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	305	Target Neighborhood Hits	361	Shared Neighborhood Hits	16
SwissProt Accessions	P09017	Gene names	HOXC4, HOX3E
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3E) (CP19).

CCNL2_HUMAN
NC score	0.006310 (rank : 294)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	305	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

CSPG2_MOUSE
NC score	0.006216 (rank : 295)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	305	Target Neighborhood Hits	711	Shared Neighborhood Hits	41
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CENG1_MOUSE
NC score	0.005919 (rank : 296)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	305	Target Neighborhood Hits	531	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

ADAM8_MOUSE
NC score	0.005388 (rank : 297)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	305	Target Neighborhood Hits	326	Shared Neighborhood Hits	12
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CD2L7_HUMAN
NC score	0.005202 (rank : 298)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	305	Target Neighborhood Hits	1275	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

RC3H1_MOUSE
NC score	0.005049 (rank : 299)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	305	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

MK07_MOUSE
NC score	0.004945 (rank : 300)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	305	Target Neighborhood Hits	1054	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

ADCY3_HUMAN
NC score	0.004765 (rank : 301)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	305	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O60266, Q9UDB1	Gene names	ADCY3, KIAA0511
Domain Architecture
Description	Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III) (Adenylate cyclase, olfactive type) (ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3).

DEN2A_HUMAN
NC score	0.004752 (rank : 302)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	305	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

SORC3_HUMAN
NC score	0.004192 (rank : 303)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	305	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

BRSK2_HUMAN
NC score	0.003849 (rank : 304)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	305	Target Neighborhood Hits	897	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

LIRA4_HUMAN
NC score	0.003737 (rank : 305)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	305	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P59901	Gene names	LILRA4, ILT7
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily A member 4 precursor (Immunoglobulin-like transcript 7) (ILT-7) (CD85g antigen).

GALT5_HUMAN
NC score	0.003702 (rank : 306)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	305	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M9, Q9UGK7, Q9UHL6	Gene names	GALNT5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

GALT5_MOUSE
NC score	0.003494 (rank : 307)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	305	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C102	Gene names	Galnt5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

PGCB_MOUSE
NC score	0.003428 (rank : 308)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	305	Target Neighborhood Hits	459	Shared Neighborhood Hits	19
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

NEK1_HUMAN
NC score	0.003005 (rank : 309)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	305	Target Neighborhood Hits	1129	Shared Neighborhood Hits	41
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

GDF5_HUMAN
NC score	0.002809 (rank : 310)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	305	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

ZN219_HUMAN
NC score	0.002307 (rank : 311)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	305	Target Neighborhood Hits	876	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

FOXF2_HUMAN
NC score	0.001389 (rank : 312)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	305	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q12947, Q9UQ85	Gene names	FOXF2, FKHL6, FREAC2
Domain Architecture
Description	Forkhead box protein F2 (Forkhead-related protein FKHL6) (Forkhead- related transcription factor 2) (FREAC-2) (Forkhead-related activator 2).

RXRG_HUMAN
NC score	0.000618 (rank : 313)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	305	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

EGR1_HUMAN
NC score	0.000021 (rank : 314)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	305	Target Neighborhood Hits	788	Shared Neighborhood Hits	21
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

STYK1_MOUSE
NC score	-0.000045 (rank : 315)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	305	Target Neighborhood Hits	779	Shared Neighborhood Hits	17
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

ZIM2_HUMAN
NC score	-0.001164 (rank : 316)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	305	Target Neighborhood Hits	718	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZV7	Gene names	ZIM2
Domain Architecture
Description	Zinc finger imprinted 2.

PRDM1_HUMAN
NC score	-0.001363 (rank : 317)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	305	Target Neighborhood Hits	734	Shared Neighborhood Hits	15
SwissProt Accessions	O75626	Gene names	PRDM1, BLIMP1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1) (Positive regulatory domain I-binding factor 1) (PRDI- binding factor 1) (PRDI-BF1).

ZN497_HUMAN
NC score	-0.002717 (rank : 318)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	305	Target Neighborhood Hits	748	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZNH5, Q6ZTD2, Q9UIA8	Gene names	ZNF497
Domain Architecture	No domain graphic available
Description	Zinc finger protein 497.

HIC2_MOUSE
NC score	-0.002911 (rank : 319)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	305	Target Neighborhood Hits	821	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).