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Network neighborhood for query Sequence : USH1C_HUMAN

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USH1C_HUMAN
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

USH1C_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	327	Target Neighborhood Hits	327	Shared Neighborhood Hits	327
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0 (rank : 2)	NC score	0.944821 (rank : 2)
Query Neighborhood Hits	327	Target Neighborhood Hits	557	Shared Neighborhood Hits	298
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

WHRN_HUMAN
θ value	4.72714e-33 (rank : 3)	NC score	0.868187 (rank : 4)
Query Neighborhood Hits	327	Target Neighborhood Hits	325	Shared Neighborhood Hits	198
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	4.00176e-32 (rank : 4)	NC score	0.857113 (rank : 5)
Query Neighborhood Hits	327	Target Neighborhood Hits	412	Shared Neighborhood Hits	197
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD7_HUMAN
θ value	1.99067e-23 (rank : 5)	NC score	0.878895 (rank : 3)
Query Neighborhood Hits	327	Target Neighborhood Hits	181	Shared Neighborhood Hits	176
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

MPDZ_HUMAN
θ value	5.8054e-15 (rank : 6)	NC score	0.765510 (rank : 8)
Query Neighborhood Hits	327	Target Neighborhood Hits	261	Shared Neighborhood Hits	193
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

DLG4_HUMAN
θ value	7.58209e-15 (rank : 7)	NC score	0.711929 (rank : 25)
Query Neighborhood Hits	327	Target Neighborhood Hits	286	Shared Neighborhood Hits	180
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

LAP4_MOUSE
θ value	7.58209e-15 (rank : 8)	NC score	0.513899 (rank : 76)
Query Neighborhood Hits	327	Target Neighborhood Hits	590	Shared Neighborhood Hits	198
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

DLG1_HUMAN
θ value	1.68911e-14 (rank : 9)	NC score	0.697844 (rank : 32)
Query Neighborhood Hits	327	Target Neighborhood Hits	290	Shared Neighborhood Hits	177
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	2.20605e-14 (rank : 10)	NC score	0.693769 (rank : 35)
Query Neighborhood Hits	327	Target Neighborhood Hits	285	Shared Neighborhood Hits	174
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG4_MOUSE
θ value	2.20605e-14 (rank : 11)	NC score	0.712637 (rank : 24)
Query Neighborhood Hits	327	Target Neighborhood Hits	282	Shared Neighborhood Hits	181
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

MPDZ_MOUSE
θ value	2.20605e-14 (rank : 12)	NC score	0.766639 (rank : 6)
Query Neighborhood Hits	327	Target Neighborhood Hits	298	Shared Neighborhood Hits	193
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

LAP4_HUMAN
θ value	2.43908e-13 (rank : 13)	NC score	0.518844 (rank : 75)
Query Neighborhood Hits	327	Target Neighborhood Hits	608	Shared Neighborhood Hits	200
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

DLG3_HUMAN
θ value	9.26847e-13 (rank : 14)	NC score	0.698917 (rank : 31)
Query Neighborhood Hits	327	Target Neighborhood Hits	269	Shared Neighborhood Hits	183
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	9.26847e-13 (rank : 15)	NC score	0.701231 (rank : 30)
Query Neighborhood Hits	327	Target Neighborhood Hits	274	Shared Neighborhood Hits	183
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

INADL_MOUSE
θ value	4.59992e-12 (rank : 16)	NC score	0.766437 (rank : 7)
Query Neighborhood Hits	327	Target Neighborhood Hits	290	Shared Neighborhood Hits	194
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

INADL_HUMAN
θ value	2.98157e-11 (rank : 17)	NC score	0.759864 (rank : 13)
Query Neighborhood Hits	327	Target Neighborhood Hits	260	Shared Neighborhood Hits	187
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

NHRF2_HUMAN
θ value	6.64225e-11 (rank : 18)	NC score	0.715813 (rank : 23)
Query Neighborhood Hits	327	Target Neighborhood Hits	197	Shared Neighborhood Hits	176
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
θ value	6.64225e-11 (rank : 19)	NC score	0.709858 (rank : 26)
Query Neighborhood Hits	327	Target Neighborhood Hits	194	Shared Neighborhood Hits	176
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

NHERF_MOUSE
θ value	7.34386e-10 (rank : 20)	NC score	0.729715 (rank : 20)
Query Neighborhood Hits	327	Target Neighborhood Hits	195	Shared Neighborhood Hits	165
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PARD3_MOUSE
θ value	7.34386e-10 (rank : 21)	NC score	0.697591 (rank : 33)
Query Neighborhood Hits	327	Target Neighborhood Hits	290	Shared Neighborhood Hits	172
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDZD1_MOUSE
θ value	7.34386e-10 (rank : 22)	NC score	0.732489 (rank : 19)
Query Neighborhood Hits	327	Target Neighborhood Hits	191	Shared Neighborhood Hits	164
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD3_MOUSE
θ value	7.34386e-10 (rank : 23)	NC score	0.671972 (rank : 47)
Query Neighborhood Hits	327	Target Neighborhood Hits	171	Shared Neighborhood Hits	161
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

NHERF_HUMAN
θ value	1.25267e-09 (rank : 24)	NC score	0.716568 (rank : 22)
Query Neighborhood Hits	327	Target Neighborhood Hits	190	Shared Neighborhood Hits	167
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

MAGI1_MOUSE
θ value	2.79066e-09 (rank : 25)	NC score	0.670139 (rank : 48)
Query Neighborhood Hits	327	Target Neighborhood Hits	403	Shared Neighborhood Hits	195
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PARD3_HUMAN
θ value	2.79066e-09 (rank : 26)	NC score	0.695789 (rank : 34)
Query Neighborhood Hits	327	Target Neighborhood Hits	312	Shared Neighborhood Hits	174
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

LNX2_MOUSE
θ value	4.76016e-09 (rank : 27)	NC score	0.675572 (rank : 45)
Query Neighborhood Hits	327	Target Neighborhood Hits	407	Shared Neighborhood Hits	179
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PDZD3_HUMAN
θ value	4.76016e-09 (rank : 28)	NC score	0.687147 (rank : 41)
Query Neighborhood Hits	327	Target Neighborhood Hits	180	Shared Neighborhood Hits	163
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

ZO1_MOUSE
θ value	4.76016e-09 (rank : 29)	NC score	0.572107 (rank : 71)
Query Neighborhood Hits	327	Target Neighborhood Hits	453	Shared Neighborhood Hits	174
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LNX1_MOUSE
θ value	6.21693e-09 (rank : 30)	NC score	0.663460 (rank : 50)
Query Neighborhood Hits	327	Target Neighborhood Hits	377	Shared Neighborhood Hits	178
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MAGI1_HUMAN
θ value	6.21693e-09 (rank : 31)	NC score	0.672592 (rank : 46)
Query Neighborhood Hits	327	Target Neighborhood Hits	388	Shared Neighborhood Hits	198
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PDZD1_HUMAN
θ value	6.21693e-09 (rank : 32)	NC score	0.719515 (rank : 21)
Query Neighborhood Hits	327	Target Neighborhood Hits	190	Shared Neighborhood Hits	165
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZ11_HUMAN
θ value	8.11959e-09 (rank : 33)	NC score	0.763916 (rank : 9)
Query Neighborhood Hits	327	Target Neighborhood Hits	160	Shared Neighborhood Hits	153
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	8.11959e-09 (rank : 34)	NC score	0.760842 (rank : 12)
Query Neighborhood Hits	327	Target Neighborhood Hits	154	Shared Neighborhood Hits	146
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PZRN3_MOUSE
θ value	8.11959e-09 (rank : 35)	NC score	0.590746 (rank : 68)
Query Neighborhood Hits	327	Target Neighborhood Hits	447	Shared Neighborhood Hits	158
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RPGF6_HUMAN
θ value	8.11959e-09 (rank : 36)	NC score	0.477108 (rank : 80)
Query Neighborhood Hits	327	Target Neighborhood Hits	266	Shared Neighborhood Hits	171
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

PTN13_MOUSE
θ value	1.06045e-08 (rank : 37)	NC score	0.424932 (rank : 104)
Query Neighborhood Hits	327	Target Neighborhood Hits	426	Shared Neighborhood Hits	189
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PZRN3_HUMAN
θ value	1.38499e-08 (rank : 38)	NC score	0.584287 (rank : 70)
Query Neighborhood Hits	327	Target Neighborhood Hits	461	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

DLG2_HUMAN
θ value	2.36244e-08 (rank : 39)	NC score	0.682819 (rank : 42)
Query Neighborhood Hits	327	Target Neighborhood Hits	279	Shared Neighborhood Hits	178
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PAR3L_HUMAN
θ value	2.36244e-08 (rank : 40)	NC score	0.706682 (rank : 28)
Query Neighborhood Hits	327	Target Neighborhood Hits	297	Shared Neighborhood Hits	164
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PDZD2_HUMAN
θ value	2.36244e-08 (rank : 41)	NC score	0.666678 (rank : 49)
Query Neighborhood Hits	327	Target Neighborhood Hits	772	Shared Neighborhood Hits	187
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SNTG2_HUMAN
θ value	2.36244e-08 (rank : 42)	NC score	0.679497 (rank : 44)
Query Neighborhood Hits	327	Target Neighborhood Hits	191	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTG2_MOUSE
θ value	2.36244e-08 (rank : 43)	NC score	0.650817 (rank : 53)
Query Neighborhood Hits	327	Target Neighborhood Hits	176	Shared Neighborhood Hits	166
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

DLG2_MOUSE
θ value	3.08544e-08 (rank : 44)	NC score	0.681629 (rank : 43)
Query Neighborhood Hits	327	Target Neighborhood Hits	271	Shared Neighborhood Hits	177
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

PTN13_HUMAN
θ value	3.08544e-08 (rank : 45)	NC score	0.431996 (rank : 99)
Query Neighborhood Hits	327	Target Neighborhood Hits	471	Shared Neighborhood Hits	196
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

LNX2_HUMAN
θ value	4.0297e-08 (rank : 46)	NC score	0.661194 (rank : 51)
Query Neighborhood Hits	327	Target Neighborhood Hits	389	Shared Neighborhood Hits	180
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

ZO3_HUMAN
θ value	5.26297e-08 (rank : 47)	NC score	0.609755 (rank : 65)
Query Neighborhood Hits	327	Target Neighborhood Hits	219	Shared Neighborhood Hits	172
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_MOUSE
θ value	5.26297e-08 (rank : 48)	NC score	0.624490 (rank : 64)
Query Neighborhood Hits	327	Target Neighborhood Hits	224	Shared Neighborhood Hits	179
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

GRIP1_HUMAN
θ value	6.87365e-08 (rank : 49)	NC score	0.688033 (rank : 38)
Query Neighborhood Hits	327	Target Neighborhood Hits	231	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
θ value	6.87365e-08 (rank : 50)	NC score	0.687574 (rank : 39)
Query Neighborhood Hits	327	Target Neighborhood Hits	241	Shared Neighborhood Hits	187
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GOPC_HUMAN
θ value	1.17247e-07 (rank : 51)	NC score	0.687250 (rank : 40)
Query Neighborhood Hits	327	Target Neighborhood Hits	377	Shared Neighborhood Hits	202
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	1.99992e-07 (rank : 52)	NC score	0.693602 (rank : 36)
Query Neighborhood Hits	327	Target Neighborhood Hits	323	Shared Neighborhood Hits	188
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PZRN4_HUMAN
θ value	2.61198e-07 (rank : 53)	NC score	0.585149 (rank : 69)
Query Neighborhood Hits	327	Target Neighborhood Hits	438	Shared Neighborhood Hits	163
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

SNTA1_HUMAN
θ value	2.61198e-07 (rank : 54)	NC score	0.637219 (rank : 60)
Query Neighborhood Hits	327	Target Neighborhood Hits	186	Shared Neighborhood Hits	164
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

RPGF2_HUMAN
θ value	4.45536e-07 (rank : 55)	NC score	0.418024 (rank : 110)
Query Neighborhood Hits	327	Target Neighborhood Hits	242	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SNTA1_MOUSE
θ value	4.45536e-07 (rank : 56)	NC score	0.629936 (rank : 63)
Query Neighborhood Hits	327	Target Neighborhood Hits	170	Shared Neighborhood Hits	158
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

MAGI2_HUMAN
θ value	7.59969e-07 (rank : 57)	NC score	0.639281 (rank : 58)
Query Neighborhood Hits	327	Target Neighborhood Hits	373	Shared Neighborhood Hits	187
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	7.59969e-07 (rank : 58)	NC score	0.636021 (rank : 61)
Query Neighborhood Hits	327	Target Neighborhood Hits	370	Shared Neighborhood Hits	188
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

LIN7A_HUMAN
θ value	1.29631e-06 (rank : 59)	NC score	0.756420 (rank : 16)
Query Neighborhood Hits	327	Target Neighborhood Hits	193	Shared Neighborhood Hits	182
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	1.29631e-06 (rank : 60)	NC score	0.756568 (rank : 15)
Query Neighborhood Hits	327	Target Neighborhood Hits	193	Shared Neighborhood Hits	181
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

SNTB1_HUMAN
θ value	1.29631e-06 (rank : 61)	NC score	0.608116 (rank : 66)
Query Neighborhood Hits	327	Target Neighborhood Hits	157	Shared Neighborhood Hits	147
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTG1_MOUSE
θ value	1.29631e-06 (rank : 62)	NC score	0.640110 (rank : 57)
Query Neighborhood Hits	327	Target Neighborhood Hits	179	Shared Neighborhood Hits	169
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

LIN7B_HUMAN
θ value	1.69304e-06 (rank : 63)	NC score	0.761123 (rank : 11)
Query Neighborhood Hits	327	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

SNTB1_MOUSE
θ value	1.69304e-06 (rank : 64)	NC score	0.607653 (rank : 67)
Query Neighborhood Hits	327	Target Neighborhood Hits	160	Shared Neighborhood Hits	145
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTG1_HUMAN
θ value	1.69304e-06 (rank : 65)	NC score	0.638597 (rank : 59)
Query Neighborhood Hits	327	Target Neighborhood Hits	181	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

LIN7B_MOUSE
θ value	2.21117e-06 (rank : 66)	NC score	0.758383 (rank : 14)
Query Neighborhood Hits	327	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

SNTB2_MOUSE
θ value	2.88788e-06 (rank : 67)	NC score	0.647232 (rank : 54)
Query Neighborhood Hits	327	Target Neighborhood Hits	181	Shared Neighborhood Hits	159
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

DLG5_HUMAN
θ value	3.77169e-06 (rank : 68)	NC score	0.475888 (rank : 81)
Query Neighborhood Hits	327	Target Neighborhood Hits	1088	Shared Neighborhood Hits	238
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

IL16_MOUSE
θ value	3.77169e-06 (rank : 69)	NC score	0.633822 (rank : 62)
Query Neighborhood Hits	327	Target Neighborhood Hits	189	Shared Neighborhood Hits	136
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LIN7C_HUMAN
θ value	3.77169e-06 (rank : 70)	NC score	0.755816 (rank : 17)
Query Neighborhood Hits	327	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	3.77169e-06 (rank : 71)	NC score	0.755816 (rank : 18)
Query Neighborhood Hits	327	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

SNTB2_HUMAN
θ value	3.77169e-06 (rank : 72)	NC score	0.646287 (rank : 56)
Query Neighborhood Hits	327	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

IL16_HUMAN
θ value	6.43352e-06 (rank : 73)	NC score	0.654258 (rank : 52)
Query Neighborhood Hits	327	Target Neighborhood Hits	207	Shared Neighborhood Hits	141
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PDLI7_MOUSE
θ value	6.43352e-06 (rank : 74)	NC score	0.269156 (rank : 159)
Query Neighborhood Hits	327	Target Neighborhood Hits	279	Shared Neighborhood Hits	101
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

ARHGC_MOUSE
θ value	8.40245e-06 (rank : 75)	NC score	0.353834 (rank : 133)
Query Neighborhood Hits	327	Target Neighborhood Hits	344	Shared Neighborhood Hits	163
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

GRIP2_HUMAN
θ value	8.40245e-06 (rank : 76)	NC score	0.691272 (rank : 37)
Query Neighborhood Hits	327	Target Neighborhood Hits	256	Shared Neighborhood Hits	188
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

LAP2_HUMAN
θ value	1.43324e-05 (rank : 77)	NC score	0.262574 (rank : 164)
Query Neighborhood Hits	327	Target Neighborhood Hits	499	Shared Neighborhood Hits	112
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LNX1_HUMAN
θ value	1.87187e-05 (rank : 78)	NC score	0.646598 (rank : 55)
Query Neighborhood Hits	327	Target Neighborhood Hits	379	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PAR6A_HUMAN
θ value	3.19293e-05 (rank : 79)	NC score	0.454711 (rank : 88)
Query Neighborhood Hits	327	Target Neighborhood Hits	119	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	3.19293e-05 (rank : 80)	NC score	0.456137 (rank : 86)
Query Neighborhood Hits	327	Target Neighborhood Hits	115	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

ARHGC_HUMAN
θ value	4.1701e-05 (rank : 81)	NC score	0.356369 (rank : 132)
Query Neighborhood Hits	327	Target Neighborhood Hits	351	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

LAP2_MOUSE
θ value	5.44631e-05 (rank : 82)	NC score	0.251431 (rank : 165)
Query Neighborhood Hits	327	Target Neighborhood Hits	482	Shared Neighborhood Hits	111
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDLI7_HUMAN
θ value	5.44631e-05 (rank : 83)	NC score	0.270258 (rank : 157)
Query Neighborhood Hits	327	Target Neighborhood Hits	547	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

RIMS1_HUMAN
θ value	9.29e-05 (rank : 84)	NC score	0.282452 (rank : 154)
Query Neighborhood Hits	327	Target Neighborhood Hits	437	Shared Neighborhood Hits	129
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYJ2B_HUMAN
θ value	9.29e-05 (rank : 85)	NC score	0.763796 (rank : 10)
Query Neighborhood Hits	327	Target Neighborhood Hits	162	Shared Neighborhood Hits	157
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

TX1B3_HUMAN
θ value	9.29e-05 (rank : 86)	NC score	0.706716 (rank : 27)
Query Neighborhood Hits	327	Target Neighborhood Hits	161	Shared Neighborhood Hits	157
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	9.29e-05 (rank : 87)	NC score	0.703896 (rank : 29)
Query Neighborhood Hits	327	Target Neighborhood Hits	158	Shared Neighborhood Hits	154
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

RHPN1_MOUSE
θ value	0.000121331 (rank : 88)	NC score	0.408532 (rank : 112)
Query Neighborhood Hits	327	Target Neighborhood Hits	154	Shared Neighborhood Hits	129
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

APBA3_MOUSE
θ value	0.00020696 (rank : 89)	NC score	0.420402 (rank : 109)
Query Neighborhood Hits	327	Target Neighborhood Hits	174	Shared Neighborhood Hits	132
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SHAN1_HUMAN
θ value	0.00020696 (rank : 90)	NC score	0.230683 (rank : 169)
Query Neighborhood Hits	327	Target Neighborhood Hits	1041	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SYP2L_HUMAN
θ value	0.00020696 (rank : 91)	NC score	0.423698 (rank : 105)
Query Neighborhood Hits	327	Target Neighborhood Hits	400	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

K1849_MOUSE
θ value	0.000270298 (rank : 92)	NC score	0.490245 (rank : 78)
Query Neighborhood Hits	327	Target Neighborhood Hits	335	Shared Neighborhood Hits	153
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MPP5_HUMAN
θ value	0.000270298 (rank : 93)	NC score	0.438842 (rank : 94)
Query Neighborhood Hits	327	Target Neighborhood Hits	231	Shared Neighborhood Hits	136
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

RIMS2_HUMAN
θ value	0.000270298 (rank : 94)	NC score	0.239181 (rank : 166)
Query Neighborhood Hits	327	Target Neighborhood Hits	342	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.000270298 (rank : 95)	NC score	0.236171 (rank : 167)
Query Neighborhood Hits	327	Target Neighborhood Hits	376	Shared Neighborhood Hits	113
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

ZO1_HUMAN
θ value	0.000270298 (rank : 96)	NC score	0.556683 (rank : 72)
Query Neighborhood Hits	327	Target Neighborhood Hits	474	Shared Neighborhood Hits	172
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

AFAD_HUMAN
θ value	0.00035302 (rank : 97)	NC score	0.481070 (rank : 79)
Query Neighborhood Hits	327	Target Neighborhood Hits	689	Shared Neighborhood Hits	199
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

MPP5_MOUSE
θ value	0.00035302 (rank : 98)	NC score	0.437376 (rank : 95)
Query Neighborhood Hits	327	Target Neighborhood Hits	226	Shared Neighborhood Hits	135
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PAR6B_HUMAN
θ value	0.00035302 (rank : 99)	NC score	0.466642 (rank : 83)
Query Neighborhood Hits	327	Target Neighborhood Hits	126	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	0.00035302 (rank : 100)	NC score	0.465077 (rank : 84)
Query Neighborhood Hits	327	Target Neighborhood Hits	128	Shared Neighborhood Hits	119
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_HUMAN
θ value	0.00035302 (rank : 101)	NC score	0.468750 (rank : 82)
Query Neighborhood Hits	327	Target Neighborhood Hits	159	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

APBA3_HUMAN
θ value	0.000461057 (rank : 102)	NC score	0.432278 (rank : 98)
Query Neighborhood Hits	327	Target Neighborhood Hits	201	Shared Neighborhood Hits	134
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PAR6G_MOUSE
θ value	0.000461057 (rank : 103)	NC score	0.463941 (rank : 85)
Query Neighborhood Hits	327	Target Neighborhood Hits	121	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PDZK4_HUMAN
θ value	0.000461057 (rank : 104)	NC score	0.452562 (rank : 89)
Query Neighborhood Hits	327	Target Neighborhood Hits	165	Shared Neighborhood Hits	118
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

ARHGB_HUMAN
θ value	0.000602161 (rank : 105)	NC score	0.376316 (rank : 126)
Query Neighborhood Hits	327	Target Neighborhood Hits	375	Shared Neighborhood Hits	170
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

PDLI5_MOUSE
θ value	0.000786445 (rank : 106)	NC score	0.271611 (rank : 156)
Query Neighborhood Hits	327	Target Neighborhood Hits	287	Shared Neighborhood Hits	114
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDZK4_MOUSE
θ value	0.00102713 (rank : 107)	NC score	0.452278 (rank : 90)
Query Neighborhood Hits	327	Target Neighborhood Hits	165	Shared Neighborhood Hits	124
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

LRRC7_HUMAN
θ value	0.00134147 (rank : 108)	NC score	0.269753 (rank : 158)
Query Neighborhood Hits	327	Target Neighborhood Hits	423	Shared Neighborhood Hits	120
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	0.00134147 (rank : 109)	NC score	0.268409 (rank : 161)
Query Neighborhood Hits	327	Target Neighborhood Hits	416	Shared Neighborhood Hits	117
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PDLI5_HUMAN
θ value	0.00134147 (rank : 110)	NC score	0.271853 (rank : 155)
Query Neighborhood Hits	327	Target Neighborhood Hits	322	Shared Neighborhood Hits	114
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

APBA1_HUMAN
θ value	0.00175202 (rank : 111)	NC score	0.445736 (rank : 93)
Query Neighborhood Hits	327	Target Neighborhood Hits	325	Shared Neighborhood Hits	154
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

K1849_HUMAN
θ value	0.00228821 (rank : 112)	NC score	0.497904 (rank : 77)
Query Neighborhood Hits	327	Target Neighborhood Hits	220	Shared Neighborhood Hits	143
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

NEB1_HUMAN
θ value	0.00228821 (rank : 113)	NC score	0.423062 (rank : 106)
Query Neighborhood Hits	327	Target Neighborhood Hits	829	Shared Neighborhood Hits	195
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PCNT_HUMAN
θ value	0.00228821 (rank : 114)	NC score	0.082828 (rank : 208)
Query Neighborhood Hits	327	Target Neighborhood Hits	1551	Shared Neighborhood Hits	127
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RHPN1_HUMAN
θ value	0.00298849 (rank : 115)	NC score	0.382507 (rank : 125)
Query Neighborhood Hits	327	Target Neighborhood Hits	158	Shared Neighborhood Hits	122
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

TAOK1_HUMAN
θ value	0.00298849 (rank : 116)	NC score	0.031108 (rank : 388)
Query Neighborhood Hits	327	Target Neighborhood Hits	1734	Shared Neighborhood Hits	113
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

ZO2_MOUSE
θ value	0.00298849 (rank : 117)	NC score	0.554212 (rank : 73)
Query Neighborhood Hits	327	Target Neighborhood Hits	296	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

APBA2_HUMAN
θ value	0.00390308 (rank : 118)	NC score	0.435388 (rank : 97)
Query Neighborhood Hits	327	Target Neighborhood Hits	220	Shared Neighborhood Hits	151
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.00390308 (rank : 119)	NC score	0.436118 (rank : 96)
Query Neighborhood Hits	327	Target Neighborhood Hits	219	Shared Neighborhood Hits	150
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

PDLI1_HUMAN
θ value	0.00390308 (rank : 120)	NC score	0.341601 (rank : 139)
Query Neighborhood Hits	327	Target Neighborhood Hits	242	Shared Neighborhood Hits	102
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	0.00390308 (rank : 121)	NC score	0.344963 (rank : 137)
Query Neighborhood Hits	327	Target Neighborhood Hits	213	Shared Neighborhood Hits	100
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

RGS12_HUMAN
θ value	0.00390308 (rank : 122)	NC score	0.318165 (rank : 146)
Query Neighborhood Hits	327	Target Neighborhood Hits	333	Shared Neighborhood Hits	136
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

WDR67_HUMAN
θ value	0.00390308 (rank : 123)	NC score	0.081162 (rank : 210)
Query Neighborhood Hits	327	Target Neighborhood Hits	782	Shared Neighborhood Hits	79
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

MPP3_HUMAN
θ value	0.00509761 (rank : 124)	NC score	0.420778 (rank : 108)
Query Neighborhood Hits	327	Target Neighborhood Hits	171	Shared Neighborhood Hits	129
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

PDLI2_MOUSE
θ value	0.00509761 (rank : 125)	NC score	0.451397 (rank : 91)
Query Neighborhood Hits	327	Target Neighborhood Hits	220	Shared Neighborhood Hits	123
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

DVL1L_HUMAN
θ value	0.00665767 (rank : 126)	NC score	0.388121 (rank : 121)
Query Neighborhood Hits	327	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	0.00665767 (rank : 127)	NC score	0.403078 (rank : 113)
Query Neighborhood Hits	327	Target Neighborhood Hits	158	Shared Neighborhood Hits	117
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	0.00665767 (rank : 128)	NC score	0.396610 (rank : 117)
Query Neighborhood Hits	327	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

LDB3_HUMAN
θ value	0.00665767 (rank : 129)	NC score	0.266635 (rank : 163)
Query Neighborhood Hits	327	Target Neighborhood Hits	497	Shared Neighborhood Hits	107
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	0.00665767 (rank : 130)	NC score	0.268672 (rank : 160)
Query Neighborhood Hits	327	Target Neighborhood Hits	510	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

NEB2_HUMAN
θ value	0.00665767 (rank : 131)	NC score	0.393693 (rank : 118)
Query Neighborhood Hits	327	Target Neighborhood Hits	883	Shared Neighborhood Hits	190
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	0.00665767 (rank : 132)	NC score	0.390900 (rank : 119)
Query Neighborhood Hits	327	Target Neighborhood Hits	889	Shared Neighborhood Hits	194
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

TAOK1_MOUSE
θ value	0.00665767 (rank : 133)	NC score	0.030384 (rank : 389)
Query Neighborhood Hits	327	Target Neighborhood Hits	1720	Shared Neighborhood Hits	114
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

CAR10_HUMAN
θ value	0.0113563 (rank : 134)	NC score	0.093347 (rank : 200)
Query Neighborhood Hits	327	Target Neighborhood Hits	569	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

EM55_HUMAN
θ value	0.0113563 (rank : 135)	NC score	0.373170 (rank : 127)
Query Neighborhood Hits	327	Target Neighborhood Hits	228	Shared Neighborhood Hits	124
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

LIPA1_HUMAN
θ value	0.0148317 (rank : 136)	NC score	0.067773 (rank : 235)
Query Neighborhood Hits	327	Target Neighborhood Hits	1294	Shared Neighborhood Hits	115
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MPP3_MOUSE
θ value	0.0148317 (rank : 137)	NC score	0.422329 (rank : 107)
Query Neighborhood Hits	327	Target Neighborhood Hits	165	Shared Neighborhood Hits	129
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

SYP2L_MOUSE
θ value	0.0148317 (rank : 138)	NC score	0.330945 (rank : 145)
Query Neighborhood Hits	327	Target Neighborhood Hits	289	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ZO2_HUMAN
θ value	0.0148317 (rank : 139)	NC score	0.551594 (rank : 74)
Query Neighborhood Hits	327	Target Neighborhood Hits	289	Shared Neighborhood Hits	170
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

EM55_MOUSE
θ value	0.0193708 (rank : 140)	NC score	0.368923 (rank : 129)
Query Neighborhood Hits	327	Target Neighborhood Hits	221	Shared Neighborhood Hits	122
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NOS1_HUMAN
θ value	0.0193708 (rank : 141)	NC score	0.312375 (rank : 147)
Query Neighborhood Hits	327	Target Neighborhood Hits	218	Shared Neighborhood Hits	136
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PTN3_HUMAN
θ value	0.0193708 (rank : 142)	NC score	0.171737 (rank : 176)
Query Neighborhood Hits	327	Target Neighborhood Hits	258	Shared Neighborhood Hits	118
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SDCB1_HUMAN
θ value	0.0193708 (rank : 143)	NC score	0.429661 (rank : 101)
Query Neighborhood Hits	327	Target Neighborhood Hits	150	Shared Neighborhood Hits	138
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	0.0193708 (rank : 144)	NC score	0.430886 (rank : 100)
Query Neighborhood Hits	327	Target Neighborhood Hits	144	Shared Neighborhood Hits	129
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

DVL2_HUMAN
θ value	0.0252991 (rank : 145)	NC score	0.384410 (rank : 124)
Query Neighborhood Hits	327	Target Neighborhood Hits	223	Shared Neighborhood Hits	115
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	0.0252991 (rank : 146)	NC score	0.385392 (rank : 122)
Query Neighborhood Hits	327	Target Neighborhood Hits	233	Shared Neighborhood Hits	113
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL3_HUMAN
θ value	0.0252991 (rank : 147)	NC score	0.398799 (rank : 115)
Query Neighborhood Hits	327	Target Neighborhood Hits	194	Shared Neighborhood Hits	114
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	0.0252991 (rank : 148)	NC score	0.398274 (rank : 116)
Query Neighborhood Hits	327	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

MPP4_HUMAN
θ value	0.0252991 (rank : 149)	NC score	0.450577 (rank : 92)
Query Neighborhood Hits	327	Target Neighborhood Hits	205	Shared Neighborhood Hits	145
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDLI2_HUMAN
θ value	0.0252991 (rank : 150)	NC score	0.455331 (rank : 87)
Query Neighborhood Hits	327	Target Neighborhood Hits	245	Shared Neighborhood Hits	128
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDLI3_HUMAN
θ value	0.0252991 (rank : 151)	NC score	0.349844 (rank : 134)
Query Neighborhood Hits	327	Target Neighborhood Hits	199	Shared Neighborhood Hits	107
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI3_MOUSE
θ value	0.0252991 (rank : 152)	NC score	0.334765 (rank : 143)
Query Neighborhood Hits	327	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

APXL_HUMAN
θ value	0.0330416 (rank : 153)	NC score	0.340066 (rank : 140)
Query Neighborhood Hits	327	Target Neighborhood Hits	553	Shared Neighborhood Hits	118
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

MAST2_MOUSE
θ value	0.0330416 (rank : 154)	NC score	0.071081 (rank : 224)
Query Neighborhood Hits	327	Target Neighborhood Hits	1110	Shared Neighborhood Hits	132
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SVIL_MOUSE
θ value	0.0330416 (rank : 155)	NC score	0.032399 (rank : 385)
Query Neighborhood Hits	327	Target Neighborhood Hits	439	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

PCNT_MOUSE
θ value	0.0431538 (rank : 156)	NC score	0.085731 (rank : 205)
Query Neighborhood Hits	327	Target Neighborhood Hits	1207	Shared Neighborhood Hits	120
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

MAST2_HUMAN
θ value	0.0563607 (rank : 157)	NC score	0.072317 (rank : 219)
Query Neighborhood Hits	327	Target Neighborhood Hits	1189	Shared Neighborhood Hits	135
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PTN4_HUMAN
θ value	0.0563607 (rank : 158)	NC score	0.171885 (rank : 175)
Query Neighborhood Hits	327	Target Neighborhood Hits	303	Shared Neighborhood Hits	122
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

SYNP2_MOUSE
θ value	0.0563607 (rank : 159)	NC score	0.362102 (rank : 131)
Query Neighborhood Hits	327	Target Neighborhood Hits	252	Shared Neighborhood Hits	120
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

GOGA1_MOUSE
θ value	0.0736092 (rank : 160)	NC score	0.054359 (rank : 285)
Query Neighborhood Hits	327	Target Neighborhood Hits	994	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PSCBP_MOUSE
θ value	0.0736092 (rank : 161)	NC score	0.409356 (rank : 111)
Query Neighborhood Hits	327	Target Neighborhood Hits	118	Shared Neighborhood Hits	114
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

SHAN2_HUMAN
θ value	0.0736092 (rank : 162)	NC score	0.339386 (rank : 141)
Query Neighborhood Hits	327	Target Neighborhood Hits	346	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	0.0736092 (rank : 163)	NC score	0.308157 (rank : 149)
Query Neighborhood Hits	327	Target Neighborhood Hits	446	Shared Neighborhood Hits	128
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

HIP1R_HUMAN
θ value	0.0961366 (rank : 164)	NC score	0.065098 (rank : 237)
Query Neighborhood Hits	327	Target Neighborhood Hits	809	Shared Neighborhood Hits	92
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

ITSN1_HUMAN
θ value	0.0961366 (rank : 165)	NC score	0.077365 (rank : 214)
Query Neighborhood Hits	327	Target Neighborhood Hits	1757	Shared Neighborhood Hits	149
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MAST1_HUMAN
θ value	0.0961366 (rank : 166)	NC score	0.070293 (rank : 229)
Query Neighborhood Hits	327	Target Neighborhood Hits	1146	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	0.0961366 (rank : 167)	NC score	0.071605 (rank : 222)
Query Neighborhood Hits	327	Target Neighborhood Hits	1123	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SDCB2_MOUSE
θ value	0.0961366 (rank : 168)	NC score	0.372767 (rank : 128)
Query Neighborhood Hits	327	Target Neighborhood Hits	118	Shared Neighborhood Hits	110
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

GIPC1_MOUSE
θ value	0.125558 (rank : 169)	NC score	0.231607 (rank : 168)
Query Neighborhood Hits	327	Target Neighborhood Hits	92	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

ITSN1_MOUSE
θ value	0.125558 (rank : 170)	NC score	0.077968 (rank : 213)
Query Neighborhood Hits	327	Target Neighborhood Hits	1669	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

LMO7_HUMAN
θ value	0.125558 (rank : 171)	NC score	0.167796 (rank : 177)
Query Neighborhood Hits	327	Target Neighborhood Hits	507	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MPP4_MOUSE
θ value	0.125558 (rank : 172)	NC score	0.400677 (rank : 114)
Query Neighborhood Hits	327	Target Neighborhood Hits	188	Shared Neighborhood Hits	124
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

PCLO_MOUSE
θ value	0.125558 (rank : 173)	NC score	0.194001 (rank : 173)
Query Neighborhood Hits	327	Target Neighborhood Hits	2275	Shared Neighborhood Hits	202
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDLI4_HUMAN
θ value	0.125558 (rank : 174)	NC score	0.331848 (rank : 144)
Query Neighborhood Hits	327	Target Neighborhood Hits	245	Shared Neighborhood Hits	108
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI4_MOUSE
θ value	0.125558 (rank : 175)	NC score	0.336454 (rank : 142)
Query Neighborhood Hits	327	Target Neighborhood Hits	233	Shared Neighborhood Hits	110
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

STMN1_HUMAN
θ value	0.125558 (rank : 176)	NC score	0.063915 (rank : 239)
Query Neighborhood Hits	327	Target Neighborhood Hits	554	Shared Neighborhood Hits	59
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

SYNP2_HUMAN
θ value	0.125558 (rank : 177)	NC score	0.310873 (rank : 148)
Query Neighborhood Hits	327	Target Neighborhood Hits	323	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

MY18A_HUMAN
θ value	0.163984 (rank : 178)	NC score	0.112495 (rank : 190)
Query Neighborhood Hits	327	Target Neighborhood Hits	1929	Shared Neighborhood Hits	243
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PSMD9_HUMAN
θ value	0.163984 (rank : 179)	NC score	0.123569 (rank : 184)
Query Neighborhood Hits	327	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

SI1L2_HUMAN
θ value	0.163984 (rank : 180)	NC score	0.109220 (rank : 191)
Query Neighborhood Hits	327	Target Neighborhood Hits	131	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	0.163984 (rank : 181)	NC score	0.107404 (rank : 192)
Query Neighborhood Hits	327	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

STK10_MOUSE
θ value	0.163984 (rank : 182)	NC score	0.031866 (rank : 387)
Query Neighborhood Hits	327	Target Neighborhood Hits	2132	Shared Neighborhood Hits	124
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

LIPA2_HUMAN
θ value	0.21417 (rank : 183)	NC score	0.068621 (rank : 232)
Query Neighborhood Hits	327	Target Neighborhood Hits	1044	Shared Neighborhood Hits	115
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

GIPC1_HUMAN
θ value	0.279714 (rank : 184)	NC score	0.217450 (rank : 172)
Query Neighborhood Hits	327	Target Neighborhood Hits	91	Shared Neighborhood Hits	82
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

HIP1R_MOUSE
θ value	0.279714 (rank : 185)	NC score	0.063471 (rank : 243)
Query Neighborhood Hits	327	Target Neighborhood Hits	959	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

NOS1_MOUSE
θ value	0.279714 (rank : 186)	NC score	0.267527 (rank : 162)
Query Neighborhood Hits	327	Target Neighborhood Hits	155	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NUF2_MOUSE
θ value	0.279714 (rank : 187)	NC score	0.056680 (rank : 268)
Query Neighborhood Hits	327	Target Neighborhood Hits	585	Shared Neighborhood Hits	66
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

SI1L1_HUMAN
θ value	0.279714 (rank : 188)	NC score	0.101843 (rank : 193)
Query Neighborhood Hits	327	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
θ value	0.279714 (rank : 189)	NC score	0.100849 (rank : 195)
Query Neighborhood Hits	327	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

ZWINT_HUMAN
θ value	0.279714 (rank : 190)	NC score	0.071269 (rank : 223)
Query Neighborhood Hits	327	Target Neighborhood Hits	333	Shared Neighborhood Hits	52
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

GRASP_HUMAN
θ value	0.365318 (rank : 191)	NC score	0.429298 (rank : 102)
Query Neighborhood Hits	327	Target Neighborhood Hits	147	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	0.365318 (rank : 192)	NC score	0.427154 (rank : 103)
Query Neighborhood Hits	327	Target Neighborhood Hits	131	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

HTRA3_MOUSE
θ value	0.365318 (rank : 193)	NC score	0.133678 (rank : 179)
Query Neighborhood Hits	327	Target Neighborhood Hits	156	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

MRCKB_HUMAN
θ value	0.365318 (rank : 194)	NC score	0.031970 (rank : 386)
Query Neighborhood Hits	327	Target Neighborhood Hits	2239	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PSCBP_HUMAN
θ value	0.365318 (rank : 195)	NC score	0.366781 (rank : 130)
Query Neighborhood Hits	327	Target Neighborhood Hits	123	Shared Neighborhood Hits	118
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

ANR26_HUMAN
θ value	0.47712 (rank : 196)	NC score	0.045261 (rank : 362)
Query Neighborhood Hits	327	Target Neighborhood Hits	1614	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CSKP_MOUSE
θ value	0.47712 (rank : 197)	NC score	0.121122 (rank : 187)
Query Neighborhood Hits	327	Target Neighborhood Hits	1027	Shared Neighborhood Hits	130
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

LIMK1_HUMAN
θ value	0.47712 (rank : 198)	NC score	0.043054 (rank : 365)
Query Neighborhood Hits	327	Target Neighborhood Hits	1005	Shared Neighborhood Hits	88
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
θ value	0.47712 (rank : 199)	NC score	0.041171 (rank : 367)
Query Neighborhood Hits	327	Target Neighborhood Hits	1008	Shared Neighborhood Hits	88
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

MAST3_HUMAN
θ value	0.47712 (rank : 200)	NC score	0.070362 (rank : 227)
Query Neighborhood Hits	327	Target Neighborhood Hits	1128	Shared Neighborhood Hits	127
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MAST4_HUMAN
θ value	0.47712 (rank : 201)	NC score	0.072155 (rank : 220)
Query Neighborhood Hits	327	Target Neighborhood Hits	1804	Shared Neighborhood Hits	147
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MUTED_HUMAN
θ value	0.47712 (rank : 202)	NC score	0.060405 (rank : 254)
Query Neighborhood Hits	327	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDH9, Q5THS1, Q68D56, Q8N5F9, Q9NU16	Gene names	MUTED
Domain Architecture	No domain graphic available
Description	Muted protein homolog.

CCD46_MOUSE
θ value	0.62314 (rank : 203)	NC score	0.058791 (rank : 260)
Query Neighborhood Hits	327	Target Neighborhood Hits	1405	Shared Neighborhood Hits	123
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

DDIT3_HUMAN
θ value	0.62314 (rank : 204)	NC score	0.054280 (rank : 286)
Query Neighborhood Hits	327	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

PICK1_HUMAN
θ value	0.62314 (rank : 205)	NC score	0.388538 (rank : 120)
Query Neighborhood Hits	327	Target Neighborhood Hits	132	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	0.62314 (rank : 206)	NC score	0.385233 (rank : 123)
Query Neighborhood Hits	327	Target Neighborhood Hits	131	Shared Neighborhood Hits	119
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

SDCB2_HUMAN
θ value	0.62314 (rank : 207)	NC score	0.344971 (rank : 136)
Query Neighborhood Hits	327	Target Neighborhood Hits	121	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

STMN1_MOUSE
θ value	0.62314 (rank : 208)	NC score	0.060847 (rank : 253)
Query Neighborhood Hits	327	Target Neighborhood Hits	560	Shared Neighborhood Hits	61
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

STXB4_MOUSE
θ value	0.62314 (rank : 209)	NC score	0.345732 (rank : 135)
Query Neighborhood Hits	327	Target Neighborhood Hits	629	Shared Neighborhood Hits	153
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

CCD19_HUMAN
θ value	0.813845 (rank : 210)	NC score	0.078873 (rank : 212)
Query Neighborhood Hits	327	Target Neighborhood Hits	639	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CI093_HUMAN
θ value	0.813845 (rank : 211)	NC score	0.062886 (rank : 245)
Query Neighborhood Hits	327	Target Neighborhood Hits	1088	Shared Neighborhood Hits	105
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CP135_MOUSE
θ value	0.813845 (rank : 212)	NC score	0.051887 (rank : 314)
Query Neighborhood Hits	327	Target Neighborhood Hits	1278	Shared Neighborhood Hits	114
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CSKP_HUMAN
θ value	0.813845 (rank : 213)	NC score	0.123641 (rank : 183)
Query Neighborhood Hits	327	Target Neighborhood Hits	1022	Shared Neighborhood Hits	130
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

GBP5_MOUSE
θ value	0.813845 (rank : 214)	NC score	0.039275 (rank : 372)
Query Neighborhood Hits	327	Target Neighborhood Hits	254	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

LBN_HUMAN
θ value	0.813845 (rank : 215)	NC score	0.050020 (rank : 348)
Query Neighborhood Hits	327	Target Neighborhood Hits	308	Shared Neighborhood Hits	49
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

MYO5C_HUMAN
θ value	0.813845 (rank : 216)	NC score	0.041064 (rank : 368)
Query Neighborhood Hits	327	Target Neighborhood Hits	1206	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NOP14_HUMAN
θ value	0.813845 (rank : 217)	NC score	0.055226 (rank : 274)
Query Neighborhood Hits	327	Target Neighborhood Hits	573	Shared Neighborhood Hits	59
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

SI1L3_HUMAN
θ value	0.813845 (rank : 218)	NC score	0.087365 (rank : 204)
Query Neighborhood Hits	327	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

STMN2_HUMAN
θ value	0.813845 (rank : 219)	NC score	0.063532 (rank : 241)
Query Neighborhood Hits	327	Target Neighborhood Hits	458	Shared Neighborhood Hits	61
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
θ value	0.813845 (rank : 220)	NC score	0.063532 (rank : 242)
Query Neighborhood Hits	327	Target Neighborhood Hits	458	Shared Neighborhood Hits	61
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

BPAEA_HUMAN
θ value	1.06291 (rank : 221)	NC score	0.036405 (rank : 380)
Query Neighborhood Hits	327	Target Neighborhood Hits	1369	Shared Neighborhood Hits	104
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD91_HUMAN
θ value	1.06291 (rank : 222)	NC score	0.059888 (rank : 256)
Query Neighborhood Hits	327	Target Neighborhood Hits	868	Shared Neighborhood Hits	94
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

LIPA2_MOUSE
θ value	1.06291 (rank : 223)	NC score	0.059865 (rank : 257)
Query Neighborhood Hits	327	Target Neighborhood Hits	1282	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MY18B_HUMAN
θ value	1.06291 (rank : 224)	NC score	0.049840 (rank : 349)
Query Neighborhood Hits	327	Target Neighborhood Hits	1299	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CK5P2_HUMAN
θ value	1.38821 (rank : 225)	NC score	0.052712 (rank : 302)
Query Neighborhood Hits	327	Target Neighborhood Hits	1433	Shared Neighborhood Hits	116
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

GIPC3_HUMAN
θ value	1.38821 (rank : 226)	NC score	0.128315 (rank : 180)
Query Neighborhood Hits	327	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
θ value	1.38821 (rank : 227)	NC score	0.126316 (rank : 181)
Query Neighborhood Hits	327	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

GOGA4_MOUSE
θ value	1.38821 (rank : 228)	NC score	0.060985 (rank : 251)
Query Neighborhood Hits	327	Target Neighborhood Hits	1939	Shared Neighborhood Hits	134
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HTRA1_HUMAN
θ value	1.38821 (rank : 229)	NC score	0.095376 (rank : 199)
Query Neighborhood Hits	327	Target Neighborhood Hits	155	Shared Neighborhood Hits	52
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA1_MOUSE
θ value	1.38821 (rank : 230)	NC score	0.093204 (rank : 201)
Query Neighborhood Hits	327	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

HTRA3_HUMAN
θ value	1.38821 (rank : 231)	NC score	0.123141 (rank : 185)
Query Neighborhood Hits	327	Target Neighborhood Hits	152	Shared Neighborhood Hits	64
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

LRC45_HUMAN
θ value	1.38821 (rank : 232)	NC score	0.055177 (rank : 275)
Query Neighborhood Hits	327	Target Neighborhood Hits	933	Shared Neighborhood Hits	104
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRSM1_HUMAN
θ value	1.38821 (rank : 233)	NC score	0.069666 (rank : 231)
Query Neighborhood Hits	327	Target Neighborhood Hits	1078	Shared Neighborhood Hits	95
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MD1L1_HUMAN
θ value	1.38821 (rank : 234)	NC score	0.058298 (rank : 262)
Query Neighborhood Hits	327	Target Neighborhood Hits	893	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MY18A_MOUSE
θ value	1.38821 (rank : 235)	NC score	0.114626 (rank : 189)
Query Neighborhood Hits	327	Target Neighborhood Hits	1989	Shared Neighborhood Hits	240
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

XRCC4_HUMAN
θ value	1.38821 (rank : 236)	NC score	0.022379 (rank : 401)
Query Neighborhood Hits	327	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

ASPP1_MOUSE
θ value	1.81305 (rank : 237)	NC score	0.038081 (rank : 376)
Query Neighborhood Hits	327	Target Neighborhood Hits	1244	Shared Neighborhood Hits	77
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

GEMI_HUMAN
θ value	1.81305 (rank : 238)	NC score	0.048783 (rank : 354)
Query Neighborhood Hits	327	Target Neighborhood Hits	192	Shared Neighborhood Hits	31
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

KLC1_HUMAN
θ value	1.81305 (rank : 239)	NC score	0.021689 (rank : 402)
Query Neighborhood Hits	327	Target Neighborhood Hits	471	Shared Neighborhood Hits	57
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

SIPA1_HUMAN
θ value	1.81305 (rank : 240)	NC score	0.079878 (rank : 211)
Query Neighborhood Hits	327	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SLK_MOUSE
θ value	1.81305 (rank : 241)	NC score	0.023414 (rank : 398)
Query Neighborhood Hits	327	Target Neighborhood Hits	1798	Shared Neighborhood Hits	127
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

GCC2_HUMAN
θ value	2.36792 (rank : 242)	NC score	0.049148 (rank : 352)
Query Neighborhood Hits	327	Target Neighborhood Hits	1558	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA4_HUMAN
θ value	2.36792 (rank : 243)	NC score	0.060983 (rank : 252)
Query Neighborhood Hits	327	Target Neighborhood Hits	2034	Shared Neighborhood Hits	140
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

K0831_MOUSE
θ value	2.36792 (rank : 244)	NC score	0.036705 (rank : 379)
Query Neighborhood Hits	327	Target Neighborhood Hits	277	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

MPP8_HUMAN
θ value	2.36792 (rank : 245)	NC score	0.024815 (rank : 395)
Query Neighborhood Hits	327	Target Neighborhood Hits	948	Shared Neighborhood Hits	54
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

RBP24_HUMAN
θ value	2.36792 (rank : 246)	NC score	0.049226 (rank : 351)
Query Neighborhood Hits	327	Target Neighborhood Hits	1559	Shared Neighborhood Hits	122
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CS029_HUMAN
θ value	3.0926 (rank : 247)	NC score	0.041936 (rank : 366)
Query Neighborhood Hits	327	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

KI21A_HUMAN
θ value	3.0926 (rank : 248)	NC score	0.030205 (rank : 390)
Query Neighborhood Hits	327	Target Neighborhood Hits	1543	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MD1L1_MOUSE
θ value	3.0926 (rank : 249)	NC score	0.054913 (rank : 278)
Query Neighborhood Hits	327	Target Neighborhood Hits	1001	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

NUCB1_HUMAN
θ value	3.0926 (rank : 250)	NC score	0.044009 (rank : 364)
Query Neighborhood Hits	327	Target Neighborhood Hits	359	Shared Neighborhood Hits	51
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUCB1_MOUSE
θ value	3.0926 (rank : 251)	NC score	0.046191 (rank : 360)
Query Neighborhood Hits	327	Target Neighborhood Hits	414	Shared Neighborhood Hits	65
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

SLK_HUMAN
θ value	3.0926 (rank : 252)	NC score	0.023513 (rank : 397)
Query Neighborhood Hits	327	Target Neighborhood Hits	1775	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SMC1A_HUMAN
θ value	3.0926 (rank : 253)	NC score	0.050217 (rank : 341)
Query Neighborhood Hits	327	Target Neighborhood Hits	1346	Shared Neighborhood Hits	119
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	3.0926 (rank : 254)	NC score	0.048986 (rank : 353)
Query Neighborhood Hits	327	Target Neighborhood Hits	1384	Shared Neighborhood Hits	121
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

AL2SB_HUMAN
θ value	4.03905 (rank : 255)	NC score	0.048401 (rank : 355)
Query Neighborhood Hits	327	Target Neighborhood Hits	294	Shared Neighborhood Hits	50
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

ASPP1_HUMAN
θ value	4.03905 (rank : 256)	NC score	0.034037 (rank : 382)
Query Neighborhood Hits	327	Target Neighborhood Hits	956	Shared Neighborhood Hits	72
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

DTNB_MOUSE
θ value	4.03905 (rank : 257)	NC score	0.024814 (rank : 396)
Query Neighborhood Hits	327	Target Neighborhood Hits	263	Shared Neighborhood Hits	38
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

GEMI_MOUSE
θ value	4.03905 (rank : 258)	NC score	0.044089 (rank : 363)
Query Neighborhood Hits	327	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	O88513	Gene names	Gmnn
Domain Architecture
Description	Geminin.

GOGA5_HUMAN
θ value	4.03905 (rank : 259)	NC score	0.054373 (rank : 284)
Query Neighborhood Hits	327	Target Neighborhood Hits	1168	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

KRHB5_MOUSE
θ value	4.03905 (rank : 260)	NC score	0.010548 (rank : 411)
Query Neighborhood Hits	327	Target Neighborhood Hits	294	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

MLL2_HUMAN
θ value	4.03905 (rank : 261)	NC score	0.034124 (rank : 381)
Query Neighborhood Hits	327	Target Neighborhood Hits	1788	Shared Neighborhood Hits	101
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MPP6_HUMAN
θ value	4.03905 (rank : 262)	NC score	0.300206 (rank : 152)
Query Neighborhood Hits	327	Target Neighborhood Hits	180	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

STMN4_HUMAN
θ value	4.03905 (rank : 263)	NC score	0.048084 (rank : 356)
Query Neighborhood Hits	327	Target Neighborhood Hits	395	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
θ value	4.03905 (rank : 264)	NC score	0.047689 (rank : 357)
Query Neighborhood Hits	327	Target Neighborhood Hits	395	Shared Neighborhood Hits	52
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

TMF1_HUMAN
θ value	4.03905 (rank : 265)	NC score	0.053732 (rank : 292)
Query Neighborhood Hits	327	Target Neighborhood Hits	987	Shared Neighborhood Hits	99
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

WDR67_MOUSE
θ value	4.03905 (rank : 266)	NC score	0.054593 (rank : 280)
Query Neighborhood Hits	327	Target Neighborhood Hits	476	Shared Neighborhood Hits	55
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

ZN318_MOUSE
θ value	4.03905 (rank : 267)	NC score	0.026947 (rank : 391)
Query Neighborhood Hits	327	Target Neighborhood Hits	642	Shared Neighborhood Hits	53
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

CCD11_HUMAN
θ value	5.27518 (rank : 268)	NC score	0.059270 (rank : 258)
Query Neighborhood Hits	327	Target Neighborhood Hits	822	Shared Neighborhood Hits	98
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CEBPE_HUMAN
θ value	5.27518 (rank : 269)	NC score	0.017421 (rank : 406)
Query Neighborhood Hits	327	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

DTNA_HUMAN
θ value	5.27518 (rank : 270)	NC score	0.026325 (rank : 393)
Query Neighborhood Hits	327	Target Neighborhood Hits	295	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

EEA1_MOUSE
θ value	5.27518 (rank : 271)	NC score	0.046426 (rank : 359)
Query Neighborhood Hits	327	Target Neighborhood Hits	1637	Shared Neighborhood Hits	125
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

IFT74_MOUSE
θ value	5.27518 (rank : 272)	NC score	0.050237 (rank : 340)
Query Neighborhood Hits	327	Target Neighborhood Hits	939	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

MCF2_HUMAN
θ value	5.27518 (rank : 273)	NC score	0.023185 (rank : 400)
Query Neighborhood Hits	327	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

MLL3_HUMAN
θ value	5.27518 (rank : 274)	NC score	0.026140 (rank : 394)
Query Neighborhood Hits	327	Target Neighborhood Hits	1644	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MPP6_MOUSE
θ value	5.27518 (rank : 275)	NC score	0.303317 (rank : 150)
Query Neighborhood Hits	327	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MYSM1_MOUSE
θ value	5.27518 (rank : 276)	NC score	0.008666 (rank : 413)
Query Neighborhood Hits	327	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q69Z66, Q3TPV7, Q8BRP5, Q8C4N1	Gene names	Mysm1, Kiaa1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

NEK11_HUMAN
θ value	5.27518 (rank : 277)	NC score	0.007361 (rank : 414)
Query Neighborhood Hits	327	Target Neighborhood Hits	1043	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

PDE6C_HUMAN
θ value	5.27518 (rank : 278)	NC score	0.004276 (rank : 416)
Query Neighborhood Hits	327	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PLCB1_MOUSE
θ value	5.27518 (rank : 279)	NC score	0.032663 (rank : 384)
Query Neighborhood Hits	327	Target Neighborhood Hits	531	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

STIM1_HUMAN
θ value	5.27518 (rank : 280)	NC score	0.038989 (rank : 373)
Query Neighborhood Hits	327	Target Neighborhood Hits	665	Shared Neighborhood Hits	80
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	5.27518 (rank : 281)	NC score	0.037922 (rank : 378)
Query Neighborhood Hits	327	Target Neighborhood Hits	660	Shared Neighborhood Hits	79
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TBG1_MOUSE
θ value	5.27518 (rank : 282)	NC score	0.002080 (rank : 418)
Query Neighborhood Hits	327	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P83887, Q9Z310	Gene names	Tubg1, Tubg
Domain Architecture
Description	Tubulin gamma-1 chain (Gamma-1 tubulin) (Gamma-tubulin complex component 1) (GCP-1).

UACA_HUMAN
θ value	5.27518 (rank : 283)	NC score	0.040076 (rank : 371)
Query Neighborhood Hits	327	Target Neighborhood Hits	1622	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ASPP2_HUMAN
θ value	6.88961 (rank : 284)	NC score	0.040573 (rank : 369)
Query Neighborhood Hits	327	Target Neighborhood Hits	1156	Shared Neighborhood Hits	100
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CA065_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.056878 (rank : 266)
Query Neighborhood Hits	327	Target Neighborhood Hits	469	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CAR11_HUMAN
θ value	6.88961 (rank : 286)	NC score	0.123906 (rank : 182)
Query Neighborhood Hits	327	Target Neighborhood Hits	690	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CENPF_HUMAN
θ value	6.88961 (rank : 287)	NC score	0.053310 (rank : 294)
Query Neighborhood Hits	327	Target Neighborhood Hits	1932	Shared Neighborhood Hits	135
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP63_HUMAN
θ value	6.88961 (rank : 288)	NC score	0.049397 (rank : 350)
Query Neighborhood Hits	327	Target Neighborhood Hits	1005	Shared Neighborhood Hits	109
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CO4A4_HUMAN
θ value	6.88961 (rank : 289)	NC score	0.002525 (rank : 417)
Query Neighborhood Hits	327	Target Neighborhood Hits	440	Shared Neighborhood Hits	16
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CT2NL_HUMAN
θ value	6.88961 (rank : 290)	NC score	0.045338 (rank : 361)
Query Neighborhood Hits	327	Target Neighborhood Hits	1059	Shared Neighborhood Hits	99
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

EEA1_HUMAN
θ value	6.88961 (rank : 291)	NC score	0.051047 (rank : 325)
Query Neighborhood Hits	327	Target Neighborhood Hits	1796	Shared Neighborhood Hits	133
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

HTRA4_HUMAN
θ value	6.88961 (rank : 292)	NC score	0.075866 (rank : 216)
Query Neighborhood Hits	327	Target Neighborhood Hits	119	Shared Neighborhood Hits	44
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

KRHB1_HUMAN
θ value	6.88961 (rank : 293)	NC score	0.014020 (rank : 408)
Query Neighborhood Hits	327	Target Neighborhood Hits	461	Shared Neighborhood Hits	54
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB6_HUMAN
θ value	6.88961 (rank : 294)	NC score	0.014095 (rank : 407)
Query Neighborhood Hits	327	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

LIPA3_HUMAN
θ value	6.88961 (rank : 295)	NC score	0.061434 (rank : 250)
Query Neighborhood Hits	327	Target Neighborhood Hits	828	Shared Neighborhood Hits	98
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPA3_MOUSE
θ value	6.88961 (rank : 296)	NC score	0.063238 (rank : 244)
Query Neighborhood Hits	327	Target Neighborhood Hits	636	Shared Neighborhood Hits	88
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LRSM1_MOUSE
θ value	6.88961 (rank : 297)	NC score	0.063970 (rank : 238)
Query Neighborhood Hits	327	Target Neighborhood Hits	874	Shared Neighborhood Hits	78
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MERL_HUMAN
θ value	6.88961 (rank : 298)	NC score	0.057568 (rank : 264)
Query Neighborhood Hits	327	Target Neighborhood Hits	532	Shared Neighborhood Hits	85
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	6.88961 (rank : 299)	NC score	0.055308 (rank : 273)
Query Neighborhood Hits	327	Target Neighborhood Hits	524	Shared Neighborhood Hits	83
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MYH9_MOUSE
θ value	6.88961 (rank : 300)	NC score	0.038518 (rank : 375)
Query Neighborhood Hits	327	Target Neighborhood Hits	1829	Shared Neighborhood Hits	127
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NIN_HUMAN
θ value	6.88961 (rank : 301)	NC score	0.054381 (rank : 282)
Query Neighborhood Hits	327	Target Neighborhood Hits	1416	Shared Neighborhood Hits	125
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NOL3_MOUSE
θ value	6.88961 (rank : 302)	NC score	0.010790 (rank : 410)
Query Neighborhood Hits	327	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

NTBP1_MOUSE
θ value	6.88961 (rank : 303)	NC score	0.038881 (rank : 374)
Query Neighborhood Hits	327	Target Neighborhood Hits	528	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

PPIP1_MOUSE
θ value	6.88961 (rank : 304)	NC score	0.021267 (rank : 403)
Query Neighborhood Hits	327	Target Neighborhood Hits	377	Shared Neighborhood Hits	52
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

RGNEF_MOUSE
θ value	6.88961 (rank : 305)	NC score	0.054961 (rank : 277)
Query Neighborhood Hits	327	Target Neighborhood Hits	641	Shared Neighborhood Hits	75
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

SAS6_MOUSE
θ value	6.88961 (rank : 306)	NC score	0.056503 (rank : 269)
Query Neighborhood Hits	327	Target Neighborhood Hits	931	Shared Neighborhood Hits	96
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

TIAM1_HUMAN
θ value	6.88961 (rank : 307)	NC score	0.100464 (rank : 196)
Query Neighborhood Hits	327	Target Neighborhood Hits	225	Shared Neighborhood Hits	66
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TPM4_MOUSE
θ value	6.88961 (rank : 308)	NC score	0.040346 (rank : 370)
Query Neighborhood Hits	327	Target Neighborhood Hits	703	Shared Neighborhood Hits	82
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TPR_HUMAN
θ value	6.88961 (rank : 309)	NC score	0.054148 (rank : 288)
Query Neighborhood Hits	327	Target Neighborhood Hits	1921	Shared Neighborhood Hits	145
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRI39_MOUSE
θ value	6.88961 (rank : 310)	NC score	0.020401 (rank : 404)
Query Neighborhood Hits	327	Target Neighborhood Hits	691	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

ZN710_HUMAN
θ value	6.88961 (rank : 311)	NC score	-0.010444 (rank : 420)
Query Neighborhood Hits	327	Target Neighborhood Hits	796	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ZNF16_HUMAN
θ value	6.88961 (rank : 312)	NC score	-0.010520 (rank : 421)
Query Neighborhood Hits	327	Target Neighborhood Hits	771	Shared Neighborhood Hits	4
SwissProt Accessions	P17020, Q96FG0	Gene names	ZNF16, KOX9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 16 (Zinc finger protein KOX9).

ZWINT_MOUSE
θ value	6.88961 (rank : 313)	NC score	0.050905 (rank : 328)
Query Neighborhood Hits	327	Target Neighborhood Hits	497	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

EVPL_MOUSE
θ value	8.99809 (rank : 314)	NC score	0.046937 (rank : 358)
Query Neighborhood Hits	327	Target Neighborhood Hits	952	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

KIF14_HUMAN
θ value	8.99809 (rank : 315)	NC score	0.023361 (rank : 399)
Query Neighborhood Hits	327	Target Neighborhood Hits	732	Shared Neighborhood Hits	85
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

KRHB6_MOUSE
θ value	8.99809 (rank : 316)	NC score	0.013826 (rank : 409)
Query Neighborhood Hits	327	Target Neighborhood Hits	413	Shared Neighborhood Hits	59
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

LMNB2_HUMAN
θ value	8.99809 (rank : 317)	NC score	0.026378 (rank : 392)
Query Neighborhood Hits	327	Target Neighborhood Hits	723	Shared Neighborhood Hits	82
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

MYH11_HUMAN
θ value	8.99809 (rank : 318)	NC score	0.037983 (rank : 377)
Query Neighborhood Hits	327	Target Neighborhood Hits	1806	Shared Neighborhood Hits	133
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PSMD9_MOUSE
θ value	8.99809 (rank : 319)	NC score	0.083297 (rank : 207)
Query Neighborhood Hits	327	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

RFIP4_HUMAN
θ value	8.99809 (rank : 320)	NC score	0.052692 (rank : 303)
Query Neighborhood Hits	327	Target Neighborhood Hits	785	Shared Neighborhood Hits	94
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

SIPA1_MOUSE
θ value	8.99809 (rank : 321)	NC score	0.062073 (rank : 249)
Query Neighborhood Hits	327	Target Neighborhood Hits	158	Shared Neighborhood Hits	33
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SKI_MOUSE
θ value	8.99809 (rank : 322)	NC score	0.033041 (rank : 383)
Query Neighborhood Hits	327	Target Neighborhood Hits	423	Shared Neighborhood Hits	59
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

STAM1_MOUSE
θ value	8.99809 (rank : 323)	NC score	0.051502 (rank : 318)
Query Neighborhood Hits	327	Target Neighborhood Hits	273	Shared Neighborhood Hits	32
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

TIE2_HUMAN
θ value	8.99809 (rank : 324)	NC score	-0.003537 (rank : 419)
Query Neighborhood Hits	327	Target Neighborhood Hits	1192	Shared Neighborhood Hits	20
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TLK1_HUMAN
θ value	8.99809 (rank : 325)	NC score	0.005488 (rank : 415)
Query Neighborhood Hits	327	Target Neighborhood Hits	967	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

TRI39_HUMAN
θ value	8.99809 (rank : 326)	NC score	0.018974 (rank : 405)
Query Neighborhood Hits	327	Target Neighborhood Hits	693	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

ZCH12_MOUSE
θ value	8.99809 (rank : 327)	NC score	0.008911 (rank : 412)
Query Neighborhood Hits	327	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZA5	Gene names	Zcchc12, Sizn
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 12 (Smad-interacting zinc finger protein).

AKAP9_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.056345 (rank : 270)
Query Neighborhood Hits	327	Target Neighborhood Hits	1710	Shared Neighborhood Hits	131
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ARHG1_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.050068 (rank : 346)
Query Neighborhood Hits	327	Target Neighborhood Hits	266	Shared Neighborhood Hits	12
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

AZI1_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.057359 (rank : 265)
Query Neighborhood Hits	327	Target Neighborhood Hits	1000	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.054194 (rank : 287)
Query Neighborhood Hits	327	Target Neighborhood Hits	990	Shared Neighborhood Hits	112
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CACB1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.050625 (rank : 332)
Query Neighborhood Hits	327	Target Neighborhood Hits	44	Shared Neighborhood Hits	19
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB1_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.052931 (rank : 298)
Query Neighborhood Hits	327	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB3_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.050319 (rank : 339)
Query Neighborhood Hits	327	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.050355 (rank : 338)
Query Neighborhood Hits	327	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CAF1A_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.052883 (rank : 299)
Query Neighborhood Hits	327	Target Neighborhood Hits	736	Shared Neighborhood Hits	102
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CALD1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.062378 (rank : 248)
Query Neighborhood Hits	327	Target Neighborhood Hits	959	Shared Neighborhood Hits	117
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CAR10_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.077061 (rank : 215)
Query Neighborhood Hits	327	Target Neighborhood Hits	407	Shared Neighborhood Hits	71
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

CAR14_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.090390 (rank : 202)
Query Neighborhood Hits	327	Target Neighborhood Hits	449	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CAR14_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.088407 (rank : 203)
Query Neighborhood Hits	327	Target Neighborhood Hits	526	Shared Neighborhood Hits	94
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

CARD9_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.050047 (rank : 347)
Query Neighborhood Hits	327	Target Neighborhood Hits	602	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CCD11_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.052868 (rank : 300)
Query Neighborhood Hits	327	Target Neighborhood Hits	498	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD21_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.052597 (rank : 305)
Query Neighborhood Hits	327	Target Neighborhood Hits	1228	Shared Neighborhood Hits	114
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD41_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.050431 (rank : 337)
Query Neighborhood Hits	327	Target Neighborhood Hits	1399	Shared Neighborhood Hits	115
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD46_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.050930 (rank : 327)
Query Neighborhood Hits	327	Target Neighborhood Hits	1430	Shared Neighborhood Hits	118
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD91_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.052334 (rank : 307)
Query Neighborhood Hits	327	Target Neighborhood Hits	699	Shared Neighborhood Hits	86
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CF060_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.050648 (rank : 331)
Query Neighborhood Hits	327	Target Neighborhood Hits	1270	Shared Neighborhood Hits	116
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CN145_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.050792 (rank : 329)
Query Neighborhood Hits	327	Target Neighborhood Hits	1196	Shared Neighborhood Hits	117
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CNKR2_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.097779 (rank : 198)
Query Neighborhood Hits	327	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.097914 (rank : 197)
Query Neighborhood Hits	327	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNTRB_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.058178 (rank : 263)
Query Neighborhood Hits	327	Target Neighborhood Hits	1029	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP135_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.050122 (rank : 343)
Query Neighborhood Hits	327	Target Neighborhood Hits	1290	Shared Neighborhood Hits	116
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP250_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.050983 (rank : 326)
Query Neighborhood Hits	327	Target Neighborhood Hits	1805	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CRK_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.050142 (rank : 342)
Query Neighborhood Hits	327	Target Neighborhood Hits	308	Shared Neighborhood Hits	30
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CT116_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.051302 (rank : 322)
Query Neighborhood Hits	327	Target Neighborhood Hits	268	Shared Neighborhood Hits	65
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

ENAH_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.060367 (rank : 255)
Query Neighborhood Hits	327	Target Neighborhood Hits	784	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EVPL_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.050122 (rank : 344)
Query Neighborhood Hits	327	Target Neighborhood Hits	895	Shared Neighborhood Hits	104
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EZRI_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.051960 (rank : 313)
Query Neighborhood Hits	327	Target Neighborhood Hits	663	Shared Neighborhood Hits	95
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.054694 (rank : 279)
Query Neighborhood Hits	327	Target Neighborhood Hits	693	Shared Neighborhood Hits	97
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

GCC2_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.050561 (rank : 333)
Query Neighborhood Hits	327	Target Neighborhood Hits	1619	Shared Neighborhood Hits	119
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GIPC2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.177454 (rank : 174)
Query Neighborhood Hits	327	Target Neighborhood Hits	93	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

GIPC2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.121311 (rank : 186)
Query Neighborhood Hits	327	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

GOGA3_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.051613 (rank : 315)
Query Neighborhood Hits	327	Target Neighborhood Hits	1437	Shared Neighborhood Hits	123
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA5_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.053824 (rank : 290)
Query Neighborhood Hits	327	Target Neighborhood Hits	1434	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.052614 (rank : 304)
Query Neighborhood Hits	327	Target Neighborhood Hits	1007	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GOGB1_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.053125 (rank : 296)
Query Neighborhood Hits	327	Target Neighborhood Hits	2297	Shared Neighborhood Hits	146
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRAP1_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.053208 (rank : 295)
Query Neighborhood Hits	327	Target Neighborhood Hits	1234	Shared Neighborhood Hits	117
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HIP1_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.052152 (rank : 311)
Query Neighborhood Hits	327	Target Neighborhood Hits	1016	Shared Neighborhood Hits	100
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HMMR_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.052137 (rank : 312)
Query Neighborhood Hits	327	Target Neighborhood Hits	1082	Shared Neighborhood Hits	109
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HTRA2_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.052961 (rank : 297)
Query Neighborhood Hits	327	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

IF3A_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.052828 (rank : 301)
Query Neighborhood Hits	327	Target Neighborhood Hits	875	Shared Neighborhood Hits	101
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.053785 (rank : 291)
Query Neighborhood Hits	327	Target Neighborhood Hits	871	Shared Neighborhood Hits	101
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.051461 (rank : 320)
Query Neighborhood Hits	327	Target Neighborhood Hits	949	Shared Neighborhood Hits	96
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.051455 (rank : 321)
Query Neighborhood Hits	327	Target Neighborhood Hits	893	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INCE_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.062544 (rank : 246)
Query Neighborhood Hits	327	Target Neighborhood Hits	978	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.062387 (rank : 247)
Query Neighborhood Hits	327	Target Neighborhood Hits	903	Shared Neighborhood Hits	116
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INVO_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.055040 (rank : 276)
Query Neighborhood Hits	327	Target Neighborhood Hits	636	Shared Neighborhood Hits	83
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

ITSN2_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.068052 (rank : 234)
Query Neighborhood Hits	327	Target Neighborhood Hits	1173	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.071672 (rank : 221)
Query Neighborhood Hits	327	Target Neighborhood Hits	1371	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

KGUA_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.223147 (rank : 171)
Query Neighborhood Hits	327	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.224431 (rank : 170)
Query Neighborhood Hits	327	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LRC45_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.054039 (rank : 289)
Query Neighborhood Hits	327	Target Neighborhood Hits	959	Shared Neighborhood Hits	103
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRC1_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.070051 (rank : 230)
Query Neighborhood Hits	327	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRRC1_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.070413 (rank : 226)
Query Neighborhood Hits	327	Target Neighborhood Hits	281	Shared Neighborhood Hits	8
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

MAP1A_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.051544 (rank : 316)
Query Neighborhood Hits	327	Target Neighborhood Hits	1626	Shared Neighborhood Hits	117
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MOES_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.058465 (rank : 261)
Query Neighborhood Hits	327	Target Neighborhood Hits	892	Shared Neighborhood Hits	112
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.059187 (rank : 259)
Query Neighborhood Hits	327	Target Neighborhood Hits	923	Shared Neighborhood Hits	113
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MPP2_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.296417 (rank : 153)
Query Neighborhood Hits	327	Target Neighborhood Hits	173	Shared Neighborhood Hits	95
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.300580 (rank : 151)
Query Neighborhood Hits	327	Target Neighborhood Hits	189	Shared Neighborhood Hits	100
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

NIN_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.050779 (rank : 330)
Query Neighborhood Hits	327	Target Neighborhood Hits	1376	Shared Neighborhood Hits	119
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NUMA1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.050496 (rank : 335)
Query Neighborhood Hits	327	Target Neighborhood Hits	1523	Shared Neighborhood Hits	133
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PDZD6_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.134035 (rank : 178)
Query Neighborhood Hits	327	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PDZD8_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.119513 (rank : 188)
Query Neighborhood Hits	327	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PEPL_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.051476 (rank : 319)
Query Neighborhood Hits	327	Target Neighborhood Hits	1141	Shared Neighborhood Hits	115
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PIBF1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.051504 (rank : 317)
Query Neighborhood Hits	327	Target Neighborhood Hits	1041	Shared Neighborhood Hits	98
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PININ_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.052402 (rank : 306)
Query Neighborhood Hits	327	Target Neighborhood Hits	753	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.050507 (rank : 334)
Query Neighborhood Hits	327	Target Neighborhood Hits	777	Shared Neighborhood Hits	79
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PRAX_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.063660 (rank : 240)
Query Neighborhood Hits	327	Target Neighborhood Hits	215	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.085126 (rank : 206)
Query Neighborhood Hits	327	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PREX1_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.052297 (rank : 309)
Query Neighborhood Hits	327	Target Neighborhood Hits	177	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RADI_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.054428 (rank : 281)
Query Neighborhood Hits	327	Target Neighborhood Hits	741	Shared Neighborhood Hits	101
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.053517 (rank : 293)
Query Neighborhood Hits	327	Target Neighborhood Hits	773	Shared Neighborhood Hits	102
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

RBM25_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.055995 (rank : 271)
Query Neighborhood Hits	327	Target Neighborhood Hits	682	Shared Neighborhood Hits	92
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RGS3_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.081619 (rank : 209)
Query Neighborhood Hits	327	Target Neighborhood Hits	1375	Shared Neighborhood Hits	81
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.067133 (rank : 236)
Query Neighborhood Hits	327	Target Neighborhood Hits	1621	Shared Neighborhood Hits	88
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RHPN2_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.056808 (rank : 267)
Query Neighborhood Hits	327	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RHPN2_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.101534 (rank : 194)
Query Neighborhood Hits	327	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RIMB1_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.055415 (rank : 272)
Query Neighborhood Hits	327	Target Neighborhood Hits	1376	Shared Neighborhood Hits	129
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMS3_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.052264 (rank : 310)
Query Neighborhood Hits	327	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.052310 (rank : 308)
Query Neighborhood Hits	327	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RNF41_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.074551 (rank : 218)
Query Neighborhood Hits	327	Target Neighborhood Hits	226	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.074827 (rank : 217)
Query Neighborhood Hits	327	Target Neighborhood Hits	224	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SDCG8_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.051206 (rank : 324)
Query Neighborhood Hits	327	Target Neighborhood Hits	1002	Shared Neighborhood Hits	99
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

STXB4_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.342044 (rank : 138)
Query Neighborhood Hits	327	Target Neighborhood Hits	616	Shared Neighborhood Hits	165
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SWP70_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.050465 (rank : 336)
Query Neighborhood Hits	327	Target Neighborhood Hits	1097	Shared Neighborhood Hits	111
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TIAM1_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.070700 (rank : 225)
Query Neighborhood Hits	327	Target Neighborhood Hits	205	Shared Neighborhood Hits	50
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TRHY_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.070314 (rank : 228)
Query Neighborhood Hits	327	Target Neighborhood Hits	1385	Shared Neighborhood Hits	131
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

WWC1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.051207 (rank : 323)
Query Neighborhood Hits	327	Target Neighborhood Hits	290	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

XE7_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.068263 (rank : 233)
Query Neighborhood Hits	327	Target Neighborhood Hits	738	Shared Neighborhood Hits	109
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ZC313_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.050106 (rank : 345)
Query Neighborhood Hits	327	Target Neighborhood Hits	772	Shared Neighborhood Hits	79
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZN291_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.054380 (rank : 283)
Query Neighborhood Hits	327	Target Neighborhood Hits	647	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

Hits sorted by NC score

USH1C_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	327	Target Neighborhood Hits	327	Shared Neighborhood Hits	327
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
NC score	0.944821 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	327	Target Neighborhood Hits	557	Shared Neighborhood Hits	298
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

PDZD7_HUMAN
NC score	0.878895 (rank : 3)	θ value	1.99067e-23 (rank : 5)
Query Neighborhood Hits	327	Target Neighborhood Hits	181	Shared Neighborhood Hits	176
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

WHRN_HUMAN
NC score	0.868187 (rank : 4)	θ value	4.72714e-33 (rank : 3)
Query Neighborhood Hits	327	Target Neighborhood Hits	325	Shared Neighborhood Hits	198
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
NC score	0.857113 (rank : 5)	θ value	4.00176e-32 (rank : 4)
Query Neighborhood Hits	327	Target Neighborhood Hits	412	Shared Neighborhood Hits	197
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

MPDZ_MOUSE
NC score	0.766639 (rank : 6)	θ value	2.20605e-14 (rank : 12)
Query Neighborhood Hits	327	Target Neighborhood Hits	298	Shared Neighborhood Hits	193
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

INADL_MOUSE
NC score	0.766437 (rank : 7)	θ value	4.59992e-12 (rank : 16)
Query Neighborhood Hits	327	Target Neighborhood Hits	290	Shared Neighborhood Hits	194
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

MPDZ_HUMAN
NC score	0.765510 (rank : 8)	θ value	5.8054e-15 (rank : 6)
Query Neighborhood Hits	327	Target Neighborhood Hits	261	Shared Neighborhood Hits	193
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PDZ11_HUMAN
NC score	0.763916 (rank : 9)	θ value	8.11959e-09 (rank : 33)
Query Neighborhood Hits	327	Target Neighborhood Hits	160	Shared Neighborhood Hits	153
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SYJ2B_HUMAN
NC score	0.763796 (rank : 10)	θ value	9.29e-05 (rank : 85)
Query Neighborhood Hits	327	Target Neighborhood Hits	162	Shared Neighborhood Hits	157
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

LIN7B_HUMAN
NC score	0.761123 (rank : 11)	θ value	1.69304e-06 (rank : 63)
Query Neighborhood Hits	327	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

PDZ11_MOUSE
NC score	0.760842 (rank : 12)	θ value	8.11959e-09 (rank : 34)
Query Neighborhood Hits	327	Target Neighborhood Hits	154	Shared Neighborhood Hits	146
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

INADL_HUMAN
NC score	0.759864 (rank : 13)	θ value	2.98157e-11 (rank : 17)
Query Neighborhood Hits	327	Target Neighborhood Hits	260	Shared Neighborhood Hits	187
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

LIN7B_MOUSE
NC score	0.758383 (rank : 14)	θ value	2.21117e-06 (rank : 66)
Query Neighborhood Hits	327	Target Neighborhood Hits	200	Shared Neighborhood Hits	185
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

LIN7A_MOUSE
NC score	0.756568 (rank : 15)	θ value	1.29631e-06 (rank : 60)
Query Neighborhood Hits	327	Target Neighborhood Hits	193	Shared Neighborhood Hits	181
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7A_HUMAN
NC score	0.756420 (rank : 16)	θ value	1.29631e-06 (rank : 59)
Query Neighborhood Hits	327	Target Neighborhood Hits	193	Shared Neighborhood Hits	182
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7C_HUMAN
NC score	0.755816 (rank : 17)	θ value	3.77169e-06 (rank : 70)
Query Neighborhood Hits	327	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.755816 (rank : 18)	θ value	3.77169e-06 (rank : 71)
Query Neighborhood Hits	327	Target Neighborhood Hits	198	Shared Neighborhood Hits	185
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PDZD1_MOUSE
NC score	0.732489 (rank : 19)	θ value	7.34386e-10 (rank : 22)
Query Neighborhood Hits	327	Target Neighborhood Hits	191	Shared Neighborhood Hits	164
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHERF_MOUSE
NC score	0.729715 (rank : 20)	θ value	7.34386e-10 (rank : 20)
Query Neighborhood Hits	327	Target Neighborhood Hits	195	Shared Neighborhood Hits	165
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD1_HUMAN
NC score	0.719515 (rank : 21)	θ value	6.21693e-09 (rank : 32)
Query Neighborhood Hits	327	Target Neighborhood Hits	190	Shared Neighborhood Hits	165
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NHERF_HUMAN
NC score	0.716568 (rank : 22)	θ value	1.25267e-09 (rank : 24)
Query Neighborhood Hits	327	Target Neighborhood Hits	190	Shared Neighborhood Hits	167
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHRF2_HUMAN
NC score	0.715813 (rank : 23)	θ value	6.64225e-11 (rank : 18)
Query Neighborhood Hits	327	Target Neighborhood Hits	197	Shared Neighborhood Hits	176
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

DLG4_MOUSE
NC score	0.712637 (rank : 24)	θ value	2.20605e-14 (rank : 11)
Query Neighborhood Hits	327	Target Neighborhood Hits	282	Shared Neighborhood Hits	181
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.711929 (rank : 25)	θ value	7.58209e-15 (rank : 7)
Query Neighborhood Hits	327	Target Neighborhood Hits	286	Shared Neighborhood Hits	180
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

NHRF2_MOUSE
NC score	0.709858 (rank : 26)	θ value	6.64225e-11 (rank : 19)
Query Neighborhood Hits	327	Target Neighborhood Hits	194	Shared Neighborhood Hits	176
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

TX1B3_HUMAN
NC score	0.706716 (rank : 27)	θ value	9.29e-05 (rank : 86)
Query Neighborhood Hits	327	Target Neighborhood Hits	161	Shared Neighborhood Hits	157
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

PAR3L_HUMAN
NC score	0.706682 (rank : 28)	θ value	2.36244e-08 (rank : 40)
Query Neighborhood Hits	327	Target Neighborhood Hits	297	Shared Neighborhood Hits	164
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

TX1B3_MOUSE
NC score	0.703896 (rank : 29)	θ value	9.29e-05 (rank : 87)
Query Neighborhood Hits	327	Target Neighborhood Hits	158	Shared Neighborhood Hits	154
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

DLG3_MOUSE
NC score	0.701231 (rank : 30)	θ value	9.26847e-13 (rank : 15)
Query Neighborhood Hits	327	Target Neighborhood Hits	274	Shared Neighborhood Hits	183
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
NC score	0.698917 (rank : 31)	θ value	9.26847e-13 (rank : 14)
Query Neighborhood Hits	327	Target Neighborhood Hits	269	Shared Neighborhood Hits	183
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_HUMAN
NC score	0.697844 (rank : 32)	θ value	1.68911e-14 (rank : 9)
Query Neighborhood Hits	327	Target Neighborhood Hits	290	Shared Neighborhood Hits	177
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

PARD3_MOUSE
NC score	0.697591 (rank : 33)	θ value	7.34386e-10 (rank : 21)
Query Neighborhood Hits	327	Target Neighborhood Hits	290	Shared Neighborhood Hits	172
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PARD3_HUMAN
NC score	0.695789 (rank : 34)	θ value	2.79066e-09 (rank : 26)
Query Neighborhood Hits	327	Target Neighborhood Hits	312	Shared Neighborhood Hits	174
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

DLG1_MOUSE
NC score	0.693769 (rank : 35)	θ value	2.20605e-14 (rank : 10)
Query Neighborhood Hits	327	Target Neighborhood Hits	285	Shared Neighborhood Hits	174
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

GOPC_MOUSE
NC score	0.693602 (rank : 36)	θ value	1.99992e-07 (rank : 52)
Query Neighborhood Hits	327	Target Neighborhood Hits	323	Shared Neighborhood Hits	188
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

GRIP2_HUMAN
NC score	0.691272 (rank : 37)	θ value	8.40245e-06 (rank : 76)
Query Neighborhood Hits	327	Target Neighborhood Hits	256	Shared Neighborhood Hits	188
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

GRIP1_HUMAN
NC score	0.688033 (rank : 38)	θ value	6.87365e-08 (rank : 49)
Query Neighborhood Hits	327	Target Neighborhood Hits	231	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
NC score	0.687574 (rank : 39)	θ value	6.87365e-08 (rank : 50)
Query Neighborhood Hits	327	Target Neighborhood Hits	241	Shared Neighborhood Hits	187
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GOPC_HUMAN
NC score	0.687250 (rank : 40)	θ value	1.17247e-07 (rank : 51)
Query Neighborhood Hits	327	Target Neighborhood Hits	377	Shared Neighborhood Hits	202
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

PDZD3_HUMAN
NC score	0.687147 (rank : 41)	θ value	4.76016e-09 (rank : 28)
Query Neighborhood Hits	327	Target Neighborhood Hits	180	Shared Neighborhood Hits	163
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

DLG2_HUMAN
NC score	0.682819 (rank : 42)	θ value	2.36244e-08 (rank : 39)
Query Neighborhood Hits	327	Target Neighborhood Hits	279	Shared Neighborhood Hits	178
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
NC score	0.681629 (rank : 43)	θ value	3.08544e-08 (rank : 44)
Query Neighborhood Hits	327	Target Neighborhood Hits	271	Shared Neighborhood Hits	177
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

SNTG2_HUMAN
NC score	0.679497 (rank : 44)	θ value	2.36244e-08 (rank : 42)
Query Neighborhood Hits	327	Target Neighborhood Hits	191	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

LNX2_MOUSE
NC score	0.675572 (rank : 45)	θ value	4.76016e-09 (rank : 27)
Query Neighborhood Hits	327	Target Neighborhood Hits	407	Shared Neighborhood Hits	179
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MAGI1_HUMAN
NC score	0.672592 (rank : 46)	θ value	6.21693e-09 (rank : 31)
Query Neighborhood Hits	327	Target Neighborhood Hits	388	Shared Neighborhood Hits	198
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PDZD3_MOUSE
NC score	0.671972 (rank : 47)	θ value	7.34386e-10 (rank : 23)
Query Neighborhood Hits	327	Target Neighborhood Hits	171	Shared Neighborhood Hits	161
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

MAGI1_MOUSE
NC score	0.670139 (rank : 48)	θ value	2.79066e-09 (rank : 25)
Query Neighborhood Hits	327	Target Neighborhood Hits	403	Shared Neighborhood Hits	195
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PDZD2_HUMAN
NC score	0.666678 (rank : 49)	θ value	2.36244e-08 (rank : 41)
Query Neighborhood Hits	327	Target Neighborhood Hits	772	Shared Neighborhood Hits	187
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LNX1_MOUSE
NC score	0.663460 (rank : 50)	θ value	6.21693e-09 (rank : 30)
Query Neighborhood Hits	327	Target Neighborhood Hits	377	Shared Neighborhood Hits	178
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
NC score	0.661194 (rank : 51)	θ value	4.0297e-08 (rank : 46)
Query Neighborhood Hits	327	Target Neighborhood Hits	389	Shared Neighborhood Hits	180
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

IL16_HUMAN
NC score	0.654258 (rank : 52)	θ value	6.43352e-06 (rank : 73)
Query Neighborhood Hits	327	Target Neighborhood Hits	207	Shared Neighborhood Hits	141
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTG2_MOUSE
NC score	0.650817 (rank : 53)	θ value	2.36244e-08 (rank : 43)
Query Neighborhood Hits	327	Target Neighborhood Hits	176	Shared Neighborhood Hits	166
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SNTB2_MOUSE
NC score	0.647232 (rank : 54)	θ value	2.88788e-06 (rank : 67)
Query Neighborhood Hits	327	Target Neighborhood Hits	181	Shared Neighborhood Hits	159
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

LNX1_HUMAN
NC score	0.646598 (rank : 55)	θ value	1.87187e-05 (rank : 78)
Query Neighborhood Hits	327	Target Neighborhood Hits	379	Shared Neighborhood Hits	170
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

SNTB2_HUMAN
NC score	0.646287 (rank : 56)	θ value	3.77169e-06 (rank : 72)
Query Neighborhood Hits	327	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG1_MOUSE
NC score	0.640110 (rank : 57)	θ value	1.29631e-06 (rank : 62)
Query Neighborhood Hits	327	Target Neighborhood Hits	179	Shared Neighborhood Hits	169
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

MAGI2_HUMAN
NC score	0.639281 (rank : 58)	θ value	7.59969e-07 (rank : 57)
Query Neighborhood Hits	327	Target Neighborhood Hits	373	Shared Neighborhood Hits	187
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

SNTG1_HUMAN
NC score	0.638597 (rank : 59)	θ value	1.69304e-06 (rank : 65)
Query Neighborhood Hits	327	Target Neighborhood Hits	181	Shared Neighborhood Hits	170
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTA1_HUMAN
NC score	0.637219 (rank : 60)	θ value	2.61198e-07 (rank : 54)
Query Neighborhood Hits	327	Target Neighborhood Hits	186	Shared Neighborhood Hits	164
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

MAGI2_MOUSE
NC score	0.636021 (rank : 61)	θ value	7.59969e-07 (rank : 58)
Query Neighborhood Hits	327	Target Neighborhood Hits	370	Shared Neighborhood Hits	188
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

IL16_MOUSE
NC score	0.633822 (rank : 62)	θ value	3.77169e-06 (rank : 69)
Query Neighborhood Hits	327	Target Neighborhood Hits	189	Shared Neighborhood Hits	136
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

SNTA1_MOUSE
NC score	0.629936 (rank : 63)	θ value	4.45536e-07 (rank : 56)
Query Neighborhood Hits	327	Target Neighborhood Hits	170	Shared Neighborhood Hits	158
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

ZO3_MOUSE
NC score	0.624490 (rank : 64)	θ value	5.26297e-08 (rank : 48)
Query Neighborhood Hits	327	Target Neighborhood Hits	224	Shared Neighborhood Hits	179
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_HUMAN
NC score	0.609755 (rank : 65)	θ value	5.26297e-08 (rank : 47)
Query Neighborhood Hits	327	Target Neighborhood Hits	219	Shared Neighborhood Hits	172
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNTB1_HUMAN
NC score	0.608116 (rank : 66)	θ value	1.29631e-06 (rank : 61)
Query Neighborhood Hits	327	Target Neighborhood Hits	157	Shared Neighborhood Hits	147
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
NC score	0.607653 (rank : 67)	θ value	1.69304e-06 (rank : 64)
Query Neighborhood Hits	327	Target Neighborhood Hits	160	Shared Neighborhood Hits	145
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

PZRN3_MOUSE
NC score	0.590746 (rank : 68)	θ value	8.11959e-09 (rank : 35)
Query Neighborhood Hits	327	Target Neighborhood Hits	447	Shared Neighborhood Hits	158
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
NC score	0.585149 (rank : 69)	θ value	2.61198e-07 (rank : 53)
Query Neighborhood Hits	327	Target Neighborhood Hits	438	Shared Neighborhood Hits	163
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PZRN3_HUMAN
NC score	0.584287 (rank : 70)	θ value	1.38499e-08 (rank : 38)
Query Neighborhood Hits	327	Target Neighborhood Hits	461	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ZO1_MOUSE
NC score	0.572107 (rank : 71)	θ value	4.76016e-09 (rank : 29)
Query Neighborhood Hits	327	Target Neighborhood Hits	453	Shared Neighborhood Hits	174
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_HUMAN
NC score	0.556683 (rank : 72)	θ value	0.000270298 (rank : 96)
Query Neighborhood Hits	327	Target Neighborhood Hits	474	Shared Neighborhood Hits	172
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_MOUSE
NC score	0.554212 (rank : 73)	θ value	0.00298849 (rank : 117)
Query Neighborhood Hits	327	Target Neighborhood Hits	296	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_HUMAN
NC score	0.551594 (rank : 74)	θ value	0.0148317 (rank : 139)
Query Neighborhood Hits	327	Target Neighborhood Hits	289	Shared Neighborhood Hits	170
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

LAP4_HUMAN
NC score	0.518844 (rank : 75)	θ value	2.43908e-13 (rank : 13)
Query Neighborhood Hits	327	Target Neighborhood Hits	608	Shared Neighborhood Hits	200
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LAP4_MOUSE
NC score	0.513899 (rank : 76)	θ value	7.58209e-15 (rank : 8)
Query Neighborhood Hits	327	Target Neighborhood Hits	590	Shared Neighborhood Hits	198
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

K1849_HUMAN
NC score	0.497904 (rank : 77)	θ value	0.00228821 (rank : 112)
Query Neighborhood Hits	327	Target Neighborhood Hits	220	Shared Neighborhood Hits	143
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

K1849_MOUSE
NC score	0.490245 (rank : 78)	θ value	0.000270298 (rank : 92)
Query Neighborhood Hits	327	Target Neighborhood Hits	335	Shared Neighborhood Hits	153
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

AFAD_HUMAN
NC score	0.481070 (rank : 79)	θ value	0.00035302 (rank : 97)
Query Neighborhood Hits	327	Target Neighborhood Hits	689	Shared Neighborhood Hits	199
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

RPGF6_HUMAN
NC score	0.477108 (rank : 80)	θ value	8.11959e-09 (rank : 36)
Query Neighborhood Hits	327	Target Neighborhood Hits	266	Shared Neighborhood Hits	171
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

DLG5_HUMAN
NC score	0.475888 (rank : 81)	θ value	3.77169e-06 (rank : 68)
Query Neighborhood Hits	327	Target Neighborhood Hits	1088	Shared Neighborhood Hits	238
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PAR6G_HUMAN
NC score	0.468750 (rank : 82)	θ value	0.00035302 (rank : 101)
Query Neighborhood Hits	327	Target Neighborhood Hits	159	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6B_HUMAN
NC score	0.466642 (rank : 83)	θ value	0.00035302 (rank : 99)
Query Neighborhood Hits	327	Target Neighborhood Hits	126	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
NC score	0.465077 (rank : 84)	θ value	0.00035302 (rank : 100)
Query Neighborhood Hits	327	Target Neighborhood Hits	128	Shared Neighborhood Hits	119
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_MOUSE
NC score	0.463941 (rank : 85)	θ value	0.000461057 (rank : 103)
Query Neighborhood Hits	327	Target Neighborhood Hits	121	Shared Neighborhood Hits	112
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PAR6A_MOUSE
NC score	0.456137 (rank : 86)	θ value	3.19293e-05 (rank : 80)
Query Neighborhood Hits	327	Target Neighborhood Hits	115	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PDLI2_HUMAN
NC score	0.455331 (rank : 87)	θ value	0.0252991 (rank : 150)
Query Neighborhood Hits	327	Target Neighborhood Hits	245	Shared Neighborhood Hits	128
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PAR6A_HUMAN
NC score	0.454711 (rank : 88)	θ value	3.19293e-05 (rank : 79)
Query Neighborhood Hits	327	Target Neighborhood Hits	119	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PDZK4_HUMAN
NC score	0.452562 (rank : 89)	θ value	0.000461057 (rank : 104)
Query Neighborhood Hits	327	Target Neighborhood Hits	165	Shared Neighborhood Hits	118
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
NC score	0.452278 (rank : 90)	θ value	0.00102713 (rank : 107)
Query Neighborhood Hits	327	Target Neighborhood Hits	165	Shared Neighborhood Hits	124
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDLI2_MOUSE
NC score	0.451397 (rank : 91)	θ value	0.00509761 (rank : 125)
Query Neighborhood Hits	327	Target Neighborhood Hits	220	Shared Neighborhood Hits	123
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

MPP4_HUMAN
NC score	0.450577 (rank : 92)	θ value	0.0252991 (rank : 149)
Query Neighborhood Hits	327	Target Neighborhood Hits	205	Shared Neighborhood Hits	145
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

APBA1_HUMAN
NC score	0.445736 (rank : 93)	θ value	0.00175202 (rank : 111)
Query Neighborhood Hits	327	Target Neighborhood Hits	325	Shared Neighborhood Hits	154
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

MPP5_HUMAN
NC score	0.438842 (rank : 94)	θ value	0.000270298 (rank : 93)
Query Neighborhood Hits	327	Target Neighborhood Hits	231	Shared Neighborhood Hits	136
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.437376 (rank : 95)	θ value	0.00035302 (rank : 98)
Query Neighborhood Hits	327	Target Neighborhood Hits	226	Shared Neighborhood Hits	135
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

APBA2_MOUSE
NC score	0.436118 (rank : 96)	θ value	0.00390308 (rank : 119)
Query Neighborhood Hits	327	Target Neighborhood Hits	219	Shared Neighborhood Hits	150
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.435388 (rank : 97)	θ value	0.00390308 (rank : 118)
Query Neighborhood Hits	327	Target Neighborhood Hits	220	Shared Neighborhood Hits	151
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_HUMAN
NC score	0.432278 (rank : 98)	θ value	0.000461057 (rank : 102)
Query Neighborhood Hits	327	Target Neighborhood Hits	201	Shared Neighborhood Hits	134
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PTN13_HUMAN
NC score	0.431996 (rank : 99)	θ value	3.08544e-08 (rank : 45)
Query Neighborhood Hits	327	Target Neighborhood Hits	471	Shared Neighborhood Hits	196
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SDCB1_MOUSE
NC score	0.430886 (rank : 100)	θ value	0.0193708 (rank : 144)
Query Neighborhood Hits	327	Target Neighborhood Hits	144	Shared Neighborhood Hits	129
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SDCB1_HUMAN
NC score	0.429661 (rank : 101)	θ value	0.0193708 (rank : 143)
Query Neighborhood Hits	327	Target Neighborhood Hits	150	Shared Neighborhood Hits	138
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

GRASP_HUMAN
NC score	0.429298 (rank : 102)	θ value	0.365318 (rank : 191)
Query Neighborhood Hits	327	Target Neighborhood Hits	147	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.427154 (rank : 103)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	327	Target Neighborhood Hits	131	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

PTN13_MOUSE
NC score	0.424932 (rank : 104)	θ value	1.06045e-08 (rank : 37)
Query Neighborhood Hits	327	Target Neighborhood Hits	426	Shared Neighborhood Hits	189
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

SYP2L_HUMAN
NC score	0.423698 (rank : 105)	θ value	0.00020696 (rank : 91)
Query Neighborhood Hits	327	Target Neighborhood Hits	400	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

NEB1_HUMAN
NC score	0.423062 (rank : 106)	θ value	0.00228821 (rank : 113)
Query Neighborhood Hits	327	Target Neighborhood Hits	829	Shared Neighborhood Hits	195
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

MPP3_MOUSE
NC score	0.422329 (rank : 107)	θ value	0.0148317 (rank : 137)
Query Neighborhood Hits	327	Target Neighborhood Hits	165	Shared Neighborhood Hits	129
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP3_HUMAN
NC score	0.420778 (rank : 108)	θ value	0.00509761 (rank : 124)
Query Neighborhood Hits	327	Target Neighborhood Hits	171	Shared Neighborhood Hits	129
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

APBA3_MOUSE
NC score	0.420402 (rank : 109)	θ value	0.00020696 (rank : 89)
Query Neighborhood Hits	327	Target Neighborhood Hits	174	Shared Neighborhood Hits	132
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

RPGF2_HUMAN
NC score	0.418024 (rank : 110)	θ value	4.45536e-07 (rank : 55)
Query Neighborhood Hits	327	Target Neighborhood Hits	242	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

PSCBP_MOUSE
NC score	0.409356 (rank : 111)	θ value	0.0736092 (rank : 161)
Query Neighborhood Hits	327	Target Neighborhood Hits	118	Shared Neighborhood Hits	114
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RHPN1_MOUSE
NC score	0.408532 (rank : 112)	θ value	0.000121331 (rank : 88)
Query Neighborhood Hits	327	Target Neighborhood Hits	154	Shared Neighborhood Hits	129
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

DVL1_HUMAN
NC score	0.403078 (rank : 113)	θ value	0.00665767 (rank : 127)
Query Neighborhood Hits	327	Target Neighborhood Hits	158	Shared Neighborhood Hits	117
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

MPP4_MOUSE
NC score	0.400677 (rank : 114)	θ value	0.125558 (rank : 172)
Query Neighborhood Hits	327	Target Neighborhood Hits	188	Shared Neighborhood Hits	124
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

DVL3_HUMAN
NC score	0.398799 (rank : 115)	θ value	0.0252991 (rank : 147)
Query Neighborhood Hits	327	Target Neighborhood Hits	194	Shared Neighborhood Hits	114
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
NC score	0.398274 (rank : 116)	θ value	0.0252991 (rank : 148)
Query Neighborhood Hits	327	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL1_MOUSE
NC score	0.396610 (rank : 117)	θ value	0.00665767 (rank : 128)
Query Neighborhood Hits	327	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

NEB2_HUMAN
NC score	0.393693 (rank : 118)	θ value	0.00665767 (rank : 131)
Query Neighborhood Hits	327	Target Neighborhood Hits	883	Shared Neighborhood Hits	190
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.390900 (rank : 119)	θ value	0.00665767 (rank : 132)
Query Neighborhood Hits	327	Target Neighborhood Hits	889	Shared Neighborhood Hits	194
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PICK1_HUMAN
NC score	0.388538 (rank : 120)	θ value	0.62314 (rank : 205)
Query Neighborhood Hits	327	Target Neighborhood Hits	132	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

DVL1L_HUMAN
NC score	0.388121 (rank : 121)	θ value	0.00665767 (rank : 126)
Query Neighborhood Hits	327	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL2_MOUSE
NC score	0.385392 (rank : 122)	θ value	0.0252991 (rank : 146)
Query Neighborhood Hits	327	Target Neighborhood Hits	233	Shared Neighborhood Hits	113
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PICK1_MOUSE
NC score	0.385233 (rank : 123)	θ value	0.62314 (rank : 206)
Query Neighborhood Hits	327	Target Neighborhood Hits	131	Shared Neighborhood Hits	119
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

DVL2_HUMAN
NC score	0.384410 (rank : 124)	θ value	0.0252991 (rank : 145)
Query Neighborhood Hits	327	Target Neighborhood Hits	223	Shared Neighborhood Hits	115
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

RHPN1_HUMAN
NC score	0.382507 (rank : 125)	θ value	0.00298849 (rank : 115)
Query Neighborhood Hits	327	Target Neighborhood Hits	158	Shared Neighborhood Hits	122
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

ARHGB_HUMAN
NC score	0.376316 (rank : 126)	θ value	0.000602161 (rank : 105)
Query Neighborhood Hits	327	Target Neighborhood Hits	375	Shared Neighborhood Hits	170
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

EM55_HUMAN
NC score	0.373170 (rank : 127)	θ value	0.0113563 (rank : 135)
Query Neighborhood Hits	327	Target Neighborhood Hits	228	Shared Neighborhood Hits	124
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

SDCB2_MOUSE
NC score	0.372767 (rank : 128)	θ value	0.0961366 (rank : 168)
Query Neighborhood Hits	327	Target Neighborhood Hits	118	Shared Neighborhood Hits	110
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

EM55_MOUSE
NC score	0.368923 (rank : 129)	θ value	0.0193708 (rank : 140)
Query Neighborhood Hits	327	Target Neighborhood Hits	221	Shared Neighborhood Hits	122
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

PSCBP_HUMAN
NC score	0.366781 (rank : 130)	θ value	0.365318 (rank : 195)
Query Neighborhood Hits	327	Target Neighborhood Hits	123	Shared Neighborhood Hits	118
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

SYNP2_MOUSE
NC score	0.362102 (rank : 131)	θ value	0.0563607 (rank : 159)
Query Neighborhood Hits	327	Target Neighborhood Hits	252	Shared Neighborhood Hits	120
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

ARHGC_HUMAN
NC score	0.356369 (rank : 132)	θ value	4.1701e-05 (rank : 81)
Query Neighborhood Hits	327	Target Neighborhood Hits	351	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
NC score	0.353834 (rank : 133)	θ value	8.40245e-06 (rank : 75)
Query Neighborhood Hits	327	Target Neighborhood Hits	344	Shared Neighborhood Hits	163
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PDLI3_HUMAN
NC score	0.349844 (rank : 134)	θ value	0.0252991 (rank : 151)
Query Neighborhood Hits	327	Target Neighborhood Hits	199	Shared Neighborhood Hits	107
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

STXB4_MOUSE
NC score	0.345732 (rank : 135)	θ value	0.62314 (rank : 209)
Query Neighborhood Hits	327	Target Neighborhood Hits	629	Shared Neighborhood Hits	153
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SDCB2_HUMAN
NC score	0.344971 (rank : 136)	θ value	0.62314 (rank : 207)
Query Neighborhood Hits	327	Target Neighborhood Hits	121	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

PDLI1_MOUSE
NC score	0.344963 (rank : 137)	θ value	0.00390308 (rank : 121)
Query Neighborhood Hits	327	Target Neighborhood Hits	213	Shared Neighborhood Hits	100
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

STXB4_HUMAN
NC score	0.342044 (rank : 138)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	327	Target Neighborhood Hits	616	Shared Neighborhood Hits	165
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

PDLI1_HUMAN
NC score	0.341601 (rank : 139)	θ value	0.00390308 (rank : 120)
Query Neighborhood Hits	327	Target Neighborhood Hits	242	Shared Neighborhood Hits	102
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

APXL_HUMAN
NC score	0.340066 (rank : 140)	θ value	0.0330416 (rank : 153)
Query Neighborhood Hits	327	Target Neighborhood Hits	553	Shared Neighborhood Hits	118
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

SHAN2_HUMAN
NC score	0.339386 (rank : 141)	θ value	0.0736092 (rank : 162)
Query Neighborhood Hits	327	Target Neighborhood Hits	346	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PDLI4_MOUSE
NC score	0.336454 (rank : 142)	θ value	0.125558 (rank : 175)
Query Neighborhood Hits	327	Target Neighborhood Hits	233	Shared Neighborhood Hits	110
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDLI3_MOUSE
NC score	0.334765 (rank : 143)	θ value	0.0252991 (rank : 152)
Query Neighborhood Hits	327	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDLI4_HUMAN
NC score	0.331848 (rank : 144)	θ value	0.125558 (rank : 174)
Query Neighborhood Hits	327	Target Neighborhood Hits	245	Shared Neighborhood Hits	108
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

SYP2L_MOUSE
NC score	0.330945 (rank : 145)	θ value	0.0148317 (rank : 138)
Query Neighborhood Hits	327	Target Neighborhood Hits	289	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

RGS12_HUMAN
NC score	0.318165 (rank : 146)	θ value	0.00390308 (rank : 122)
Query Neighborhood Hits	327	Target Neighborhood Hits	333	Shared Neighborhood Hits	136
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

NOS1_HUMAN
NC score	0.312375 (rank : 147)	θ value	0.0193708 (rank : 141)
Query Neighborhood Hits	327	Target Neighborhood Hits	218	Shared Neighborhood Hits	136
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

SYNP2_HUMAN
NC score	0.310873 (rank : 148)	θ value	0.125558 (rank : 177)
Query Neighborhood Hits	327	Target Neighborhood Hits	323	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

SHAN2_MOUSE
NC score	0.308157 (rank : 149)	θ value	0.0736092 (rank : 163)
Query Neighborhood Hits	327	Target Neighborhood Hits	446	Shared Neighborhood Hits	128
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

MPP6_MOUSE
NC score	0.303317 (rank : 150)	θ value	5.27518 (rank : 275)
Query Neighborhood Hits	327	Target Neighborhood Hits	187	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP2_MOUSE
NC score	0.300580 (rank : 151)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	327	Target Neighborhood Hits	189	Shared Neighborhood Hits	100
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP6_HUMAN
NC score	0.300206 (rank : 152)	θ value	4.03905 (rank : 262)
Query Neighborhood Hits	327	Target Neighborhood Hits	180	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP2_HUMAN
NC score	0.296417 (rank : 153)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	327	Target Neighborhood Hits	173	Shared Neighborhood Hits	95
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

RIMS1_HUMAN
NC score	0.282452 (rank : 154)	θ value	9.29e-05 (rank : 84)
Query Neighborhood Hits	327	Target Neighborhood Hits	437	Shared Neighborhood Hits	129
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PDLI5_HUMAN
NC score	0.271853 (rank : 155)	θ value	0.00134147 (rank : 110)
Query Neighborhood Hits	327	Target Neighborhood Hits	322	Shared Neighborhood Hits	114
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI5_MOUSE
NC score	0.271611 (rank : 156)	θ value	0.000786445 (rank : 106)
Query Neighborhood Hits	327	Target Neighborhood Hits	287	Shared Neighborhood Hits	114
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PDLI7_HUMAN
NC score	0.270258 (rank : 157)	θ value	5.44631e-05 (rank : 83)
Query Neighborhood Hits	327	Target Neighborhood Hits	547	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LRRC7_HUMAN
NC score	0.269753 (rank : 158)	θ value	0.00134147 (rank : 108)
Query Neighborhood Hits	327	Target Neighborhood Hits	423	Shared Neighborhood Hits	120
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PDLI7_MOUSE
NC score	0.269156 (rank : 159)	θ value	6.43352e-06 (rank : 74)
Query Neighborhood Hits	327	Target Neighborhood Hits	279	Shared Neighborhood Hits	101
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

LDB3_MOUSE
NC score	0.268672 (rank : 160)	θ value	0.00665767 (rank : 130)
Query Neighborhood Hits	327	Target Neighborhood Hits	510	Shared Neighborhood Hits	104
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LRRC7_MOUSE
NC score	0.268409 (rank : 161)	θ value	0.00134147 (rank : 109)
Query Neighborhood Hits	327	Target Neighborhood Hits	416	Shared Neighborhood Hits	117
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

NOS1_MOUSE
NC score	0.267527 (rank : 162)	θ value	0.279714 (rank : 186)
Query Neighborhood Hits	327	Target Neighborhood Hits	155	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

LDB3_HUMAN
NC score	0.266635 (rank : 163)	θ value	0.00665767 (rank : 129)
Query Neighborhood Hits	327	Target Neighborhood Hits	497	Shared Neighborhood Hits	107
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LAP2_HUMAN
NC score	0.262574 (rank : 164)	θ value	1.43324e-05 (rank : 77)
Query Neighborhood Hits	327	Target Neighborhood Hits	499	Shared Neighborhood Hits	112
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
NC score	0.251431 (rank : 165)	θ value	5.44631e-05 (rank : 82)
Query Neighborhood Hits	327	Target Neighborhood Hits	482	Shared Neighborhood Hits	111
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

RIMS2_HUMAN
NC score	0.239181 (rank : 166)	θ value	0.000270298 (rank : 94)
Query Neighborhood Hits	327	Target Neighborhood Hits	342	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.236171 (rank : 167)	θ value	0.000270298 (rank : 95)
Query Neighborhood Hits	327	Target Neighborhood Hits	376	Shared Neighborhood Hits	113
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

GIPC1_MOUSE
NC score	0.231607 (rank : 168)	θ value	0.125558 (rank : 169)
Query Neighborhood Hits	327	Target Neighborhood Hits	92	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

SHAN1_HUMAN
NC score	0.230683 (rank : 169)	θ value	0.00020696 (rank : 90)
Query Neighborhood Hits	327	Target Neighborhood Hits	1041	Shared Neighborhood Hits	158
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

KGUA_MOUSE
NC score	0.224431 (rank : 170)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	327	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.223147 (rank : 171)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	327	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

GIPC1_HUMAN
NC score	0.217450 (rank : 172)	θ value	0.279714 (rank : 184)
Query Neighborhood Hits	327	Target Neighborhood Hits	91	Shared Neighborhood Hits	82
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

PCLO_MOUSE
NC score	0.194001 (rank : 173)	θ value	0.125558 (rank : 173)
Query Neighborhood Hits	327	Target Neighborhood Hits	2275	Shared Neighborhood Hits	202
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GIPC2_HUMAN
NC score	0.177454 (rank : 174)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	327	Target Neighborhood Hits	93	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

PTN4_HUMAN
NC score	0.171885 (rank : 175)	θ value	0.0563607 (rank : 158)
Query Neighborhood Hits	327	Target Neighborhood Hits	303	Shared Neighborhood Hits	122
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.171737 (rank : 176)	θ value	0.0193708 (rank : 142)
Query Neighborhood Hits	327	Target Neighborhood Hits	258	Shared Neighborhood Hits	118
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

LMO7_HUMAN
NC score	0.167796 (rank : 177)	θ value	0.125558 (rank : 171)
Query Neighborhood Hits	327	Target Neighborhood Hits	507	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

PDZD6_HUMAN
NC score	0.134035 (rank : 178)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	327	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

HTRA3_MOUSE
NC score	0.133678 (rank : 179)	θ value	0.365318 (rank : 193)
Query Neighborhood Hits	327	Target Neighborhood Hits	156	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

GIPC3_HUMAN
NC score	0.128315 (rank : 180)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	327	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TF64, O75227	Gene names	GIPC3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3.

GIPC3_MOUSE
NC score	0.126316 (rank : 181)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	327	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R5M0	Gene names	Gipc3, Rgs19ip3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC3 (Regulator of G-protein signaling 19-interacting protein 3).

CAR11_HUMAN
NC score	0.123906 (rank : 182)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	327	Target Neighborhood Hits	690	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CSKP_HUMAN
NC score	0.123641 (rank : 183)	θ value	0.813845 (rank : 213)
Query Neighborhood Hits	327	Target Neighborhood Hits	1022	Shared Neighborhood Hits	130
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

PSMD9_HUMAN
NC score	0.123569 (rank : 184)	θ value	0.163984 (rank : 179)
Query Neighborhood Hits	327	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

HTRA3_HUMAN
NC score	0.123141 (rank : 185)	θ value	1.38821 (rank : 231)
Query Neighborhood Hits	327	Target Neighborhood Hits	152	Shared Neighborhood Hits	64
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

GIPC2_MOUSE
NC score	0.121311 (rank : 186)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	327	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

CSKP_MOUSE
NC score	0.121122 (rank : 187)	θ value	0.47712 (rank : 197)
Query Neighborhood Hits	327	Target Neighborhood Hits	1027	Shared Neighborhood Hits	130
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

PDZD8_HUMAN
NC score	0.119513 (rank : 188)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	327	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

MY18A_MOUSE
NC score	0.114626 (rank : 189)	θ value	1.38821 (rank : 235)
Query Neighborhood Hits	327	Target Neighborhood Hits	1989	Shared Neighborhood Hits	240
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_HUMAN
NC score	0.112495 (rank : 190)	θ value	0.163984 (rank : 178)
Query Neighborhood Hits	327	Target Neighborhood Hits	1929	Shared Neighborhood Hits	243
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SI1L2_HUMAN
NC score	0.109220 (rank : 191)	θ value	0.163984 (rank : 180)
Query Neighborhood Hits	327	Target Neighborhood Hits	131	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
NC score	0.107404 (rank : 192)	θ value	0.163984 (rank : 181)
Query Neighborhood Hits	327	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L1_HUMAN
NC score	0.101843 (rank : 193)	θ value	0.279714 (rank : 188)
Query Neighborhood Hits	327	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

RHPN2_MOUSE
NC score	0.101534 (rank : 194)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	327	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

SI1L1_MOUSE
NC score	0.100849 (rank : 195)	θ value	0.279714 (rank : 189)
Query Neighborhood Hits	327	Target Neighborhood Hits	189	Shared Neighborhood Hits	58
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

TIAM1_HUMAN
NC score	0.100464 (rank : 196)	θ value	6.88961 (rank : 307)
Query Neighborhood Hits	327	Target Neighborhood Hits	225	Shared Neighborhood Hits	66
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

CNKR2_MOUSE
NC score	0.097914 (rank : 197)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	327	Target Neighborhood Hits	197	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.097779 (rank : 198)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	327	Target Neighborhood Hits	197	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

HTRA1_HUMAN
NC score	0.095376 (rank : 199)	θ value	1.38821 (rank : 229)
Query Neighborhood Hits	327	Target Neighborhood Hits	155	Shared Neighborhood Hits	52
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

CAR10_HUMAN
NC score	0.093347 (rank : 200)	θ value	0.0113563 (rank : 134)
Query Neighborhood Hits	327	Target Neighborhood Hits	569	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

HTRA1_MOUSE
NC score	0.093204 (rank : 201)	θ value	1.38821 (rank : 230)
Query Neighborhood Hits	327	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

CAR14_HUMAN
NC score	0.090390 (rank : 202)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	327	Target Neighborhood Hits	449	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BXL6, Q9BVB5	Gene names	CARD14, CARMA2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (CARD-containing MAGUK protein 2) (Carma 2).

CAR14_MOUSE
NC score	0.088407 (rank : 203)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	327	Target Neighborhood Hits	526	Shared Neighborhood Hits	94
SwissProt Accessions	Q99KF0	Gene names	Card14, Bimp2
Domain Architecture
Description	Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).

SI1L3_HUMAN
NC score	0.087365 (rank : 204)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	327	Target Neighborhood Hits	305	Shared Neighborhood Hits	46
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

PCNT_MOUSE
NC score	0.085731 (rank : 205)	θ value	0.0431538 (rank : 156)
Query Neighborhood Hits	327	Target Neighborhood Hits	1207	Shared Neighborhood Hits	120
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PRAX_MOUSE
NC score	0.085126 (rank : 206)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	327	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

PSMD9_MOUSE
NC score	0.083297 (rank : 207)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	327	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

PCNT_HUMAN
NC score	0.082828 (rank : 208)	θ value	0.00228821 (rank : 114)
Query Neighborhood Hits	327	Target Neighborhood Hits	1551	Shared Neighborhood Hits	127
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RGS3_HUMAN
NC score	0.081619 (rank : 209)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	327	Target Neighborhood Hits	1375	Shared Neighborhood Hits	81
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

WDR67_HUMAN
NC score	0.081162 (rank : 210)	θ value	0.00390308 (rank : 123)
Query Neighborhood Hits	327	Target Neighborhood Hits	782	Shared Neighborhood Hits	79
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

SIPA1_HUMAN
NC score	0.079878 (rank : 211)	θ value	1.81305 (rank : 240)
Query Neighborhood Hits	327	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

CCD19_HUMAN
NC score	0.078873 (rank : 212)	θ value	0.813845 (rank : 210)
Query Neighborhood Hits	327	Target Neighborhood Hits	639	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

ITSN1_MOUSE
NC score	0.077968 (rank : 213)	θ value	0.125558 (rank : 170)
Query Neighborhood Hits	327	Target Neighborhood Hits	1669	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.077365 (rank : 214)	θ value	0.0961366 (rank : 165)
Query Neighborhood Hits	327	Target Neighborhood Hits	1757	Shared Neighborhood Hits	149
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

CAR10_MOUSE
NC score	0.077061 (rank : 215)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	327	Target Neighborhood Hits	407	Shared Neighborhood Hits	71
SwissProt Accessions	P58660	Gene names	Card10, Bimp1
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).

HTRA4_HUMAN
NC score	0.075866 (rank : 216)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	327	Target Neighborhood Hits	119	Shared Neighborhood Hits	44
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

RNF41_MOUSE
NC score	0.074827 (rank : 217)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	327	Target Neighborhood Hits	224	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.074551 (rank : 218)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	327	Target Neighborhood Hits	226	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

MAST2_HUMAN
NC score	0.072317 (rank : 219)	θ value	0.0563607 (rank : 157)
Query Neighborhood Hits	327	Target Neighborhood Hits	1189	Shared Neighborhood Hits	135
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST4_HUMAN
NC score	0.072155 (rank : 220)	θ value	0.47712 (rank : 201)
Query Neighborhood Hits	327	Target Neighborhood Hits	1804	Shared Neighborhood Hits	147
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ITSN2_MOUSE
NC score	0.071672 (rank : 221)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	327	Target Neighborhood Hits	1371	Shared Neighborhood Hits	141
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MAST1_MOUSE
NC score	0.071605 (rank : 222)	θ value	0.0961366 (rank : 167)
Query Neighborhood Hits	327	Target Neighborhood Hits	1123	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ZWINT_HUMAN
NC score	0.071269 (rank : 223)	θ value	0.279714 (rank : 190)
Query Neighborhood Hits	327	Target Neighborhood Hits	333	Shared Neighborhood Hits	52
SwissProt Accessions	O95229, Q9BWD0	Gene names	ZWINT
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

MAST2_MOUSE
NC score	0.071081 (rank : 224)	θ value	0.0330416 (rank : 154)
Query Neighborhood Hits	327	Target Neighborhood Hits	1110	Shared Neighborhood Hits	132
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TIAM1_MOUSE
NC score	0.070700 (rank : 225)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	327	Target Neighborhood Hits	205	Shared Neighborhood Hits	50
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

LRRC1_MOUSE
NC score	0.070413 (rank : 226)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	327	Target Neighborhood Hits	281	Shared Neighborhood Hits	8
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

MAST3_HUMAN
NC score	0.070362 (rank : 227)	θ value	0.47712 (rank : 200)
Query Neighborhood Hits	327	Target Neighborhood Hits	1128	Shared Neighborhood Hits	127
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

TRHY_HUMAN
NC score	0.070314 (rank : 228)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	327	Target Neighborhood Hits	1385	Shared Neighborhood Hits	131
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

MAST1_HUMAN
NC score	0.070293 (rank : 229)	θ value	0.0961366 (rank : 166)
Query Neighborhood Hits	327	Target Neighborhood Hits	1146	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

LRRC1_HUMAN
NC score	0.070051 (rank : 230)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	327	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

LRSM1_HUMAN
NC score	0.069666 (rank : 231)	θ value	1.38821 (rank : 233)
Query Neighborhood Hits	327	Target Neighborhood Hits	1078	Shared Neighborhood Hits	95
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

LIPA2_HUMAN
NC score	0.068621 (rank : 232)	θ value	0.21417 (rank : 183)
Query Neighborhood Hits	327	Target Neighborhood Hits	1044	Shared Neighborhood Hits	115
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

XE7_HUMAN
NC score	0.068263 (rank : 233)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	327	Target Neighborhood Hits	738	Shared Neighborhood Hits	109
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ITSN2_HUMAN
NC score	0.068052 (rank : 234)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	327	Target Neighborhood Hits	1173	Shared Neighborhood Hits	137
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

LIPA1_HUMAN
NC score	0.067773 (rank : 235)	θ value	0.0148317 (rank : 136)
Query Neighborhood Hits	327	Target Neighborhood Hits	1294	Shared Neighborhood Hits	115
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

RGS3_MOUSE
NC score	0.067133 (rank : 236)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	327	Target Neighborhood Hits	1621	Shared Neighborhood Hits	88
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

HIP1R_HUMAN
NC score	0.065098 (rank : 237)	θ value	0.0961366 (rank : 164)
Query Neighborhood Hits	327	Target Neighborhood Hits	809	Shared Neighborhood Hits	92
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

LRSM1_MOUSE
NC score	0.063970 (rank : 238)	θ value	6.88961 (rank : 297)
Query Neighborhood Hits	327	Target Neighborhood Hits	874	Shared Neighborhood Hits	78
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

STMN1_HUMAN
NC score	0.063915 (rank : 239)	θ value	0.125558 (rank : 176)
Query Neighborhood Hits	327	Target Neighborhood Hits	554	Shared Neighborhood Hits	59
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

PRAX_HUMAN
NC score	0.063660 (rank : 240)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	327	Target Neighborhood Hits	215	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

STMN2_HUMAN
NC score	0.063532 (rank : 241)	θ value	0.813845 (rank : 219)
Query Neighborhood Hits	327	Target Neighborhood Hits	458	Shared Neighborhood Hits	61
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
NC score	0.063532 (rank : 242)	θ value	0.813845 (rank : 220)
Query Neighborhood Hits	327	Target Neighborhood Hits	458	Shared Neighborhood Hits	61
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

HIP1R_MOUSE
NC score	0.063471 (rank : 243)	θ value	0.279714 (rank : 185)
Query Neighborhood Hits	327	Target Neighborhood Hits	959	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

LIPA3_MOUSE
NC score	0.063238 (rank : 244)	θ value	6.88961 (rank : 296)
Query Neighborhood Hits	327	Target Neighborhood Hits	636	Shared Neighborhood Hits	88
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

CI093_HUMAN
NC score	0.062886 (rank : 245)	θ value	0.813845 (rank : 211)
Query Neighborhood Hits	327	Target Neighborhood Hits	1088	Shared Neighborhood Hits	105
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

INCE_HUMAN
NC score	0.062544 (rank : 246)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	327	Target Neighborhood Hits	978	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
NC score	0.062387 (rank : 247)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	327	Target Neighborhood Hits	903	Shared Neighborhood Hits	116
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

CALD1_HUMAN
NC score	0.062378 (rank : 248)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	327	Target Neighborhood Hits	959	Shared Neighborhood Hits	117
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

SIPA1_MOUSE
NC score	0.062073 (rank : 249)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	327	Target Neighborhood Hits	158	Shared Neighborhood Hits	33
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

LIPA3_HUMAN
NC score	0.061434 (rank : 250)	θ value	6.88961 (rank : 295)
Query Neighborhood Hits	327	Target Neighborhood Hits	828	Shared Neighborhood Hits	98
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

GOGA4_MOUSE
NC score	0.060985 (rank : 251)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	327	Target Neighborhood Hits	1939	Shared Neighborhood Hits	134
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA4_HUMAN
NC score	0.060983 (rank : 252)	θ value	2.36792 (rank : 243)
Query Neighborhood Hits	327	Target Neighborhood Hits	2034	Shared Neighborhood Hits	140
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

STMN1_MOUSE
NC score	0.060847 (rank : 253)	θ value	0.62314 (rank : 208)
Query Neighborhood Hits	327	Target Neighborhood Hits	560	Shared Neighborhood Hits	61
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

MUTED_HUMAN
NC score	0.060405 (rank : 254)	θ value	0.47712 (rank : 202)
Query Neighborhood Hits	327	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDH9, Q5THS1, Q68D56, Q8N5F9, Q9NU16	Gene names	MUTED
Domain Architecture	No domain graphic available
Description	Muted protein homolog.

ENAH_HUMAN
NC score	0.060367 (rank : 255)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	327	Target Neighborhood Hits	784	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

CCD91_HUMAN
NC score	0.059888 (rank : 256)	θ value	1.06291 (rank : 222)
Query Neighborhood Hits	327	Target Neighborhood Hits	868	Shared Neighborhood Hits	94
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

LIPA2_MOUSE
NC score	0.059865 (rank : 257)	θ value	1.06291 (rank : 223)
Query Neighborhood Hits	327	Target Neighborhood Hits	1282	Shared Neighborhood Hits	121
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

CCD11_HUMAN
NC score	0.059270 (rank : 258)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	327	Target Neighborhood Hits	822	Shared Neighborhood Hits	98
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

MOES_MOUSE
NC score	0.059187 (rank : 259)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	327	Target Neighborhood Hits	923	Shared Neighborhood Hits	113
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

CCD46_MOUSE
NC score	0.058791 (rank : 260)	θ value	0.62314 (rank : 203)
Query Neighborhood Hits	327	Target Neighborhood Hits	1405	Shared Neighborhood Hits	123
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

MOES_HUMAN
NC score	0.058465 (rank : 261)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	327	Target Neighborhood Hits	892	Shared Neighborhood Hits	112
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MD1L1_HUMAN
NC score	0.058298 (rank : 262)	θ value	1.38821 (rank : 234)
Query Neighborhood Hits	327	Target Neighborhood Hits	893	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CNTRB_MOUSE
NC score	0.058178 (rank : 263)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	327	Target Neighborhood Hits	1029	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

MERL_HUMAN
NC score	0.057568 (rank : 264)	θ value	6.88961 (rank : 298)
Query Neighborhood Hits	327	Target Neighborhood Hits	532	Shared Neighborhood Hits	85
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

AZI1_HUMAN
NC score	0.057359 (rank : 265)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	327	Target Neighborhood Hits	1000	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CA065_HUMAN
NC score	0.056878 (rank : 266)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	327	Target Neighborhood Hits	469	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

RHPN2_HUMAN
NC score	0.056808 (rank : 267)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	327	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

NUF2_MOUSE
NC score	0.056680 (rank : 268)	θ value	0.279714 (rank : 187)
Query Neighborhood Hits	327	Target Neighborhood Hits	585	Shared Neighborhood Hits	66
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

SAS6_MOUSE
NC score	0.056503 (rank : 269)	θ value	6.88961 (rank : 306)
Query Neighborhood Hits	327	Target Neighborhood Hits	931	Shared Neighborhood Hits	96
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

AKAP9_HUMAN
NC score	0.056345 (rank : 270)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	327	Target Neighborhood Hits	1710	Shared Neighborhood Hits	131
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

RBM25_HUMAN
NC score	0.055995 (rank : 271)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	327	Target Neighborhood Hits	682	Shared Neighborhood Hits	92
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RIMB1_MOUSE
NC score	0.055415 (rank : 272)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	327	Target Neighborhood Hits	1376	Shared Neighborhood Hits	129
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MERL_MOUSE
NC score	0.055308 (rank : 273)	θ value	6.88961 (rank : 299)
Query Neighborhood Hits	327	Target Neighborhood Hits	524	Shared Neighborhood Hits	83
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

NOP14_HUMAN
NC score	0.055226 (rank : 274)	θ value	0.813845 (rank : 217)
Query Neighborhood Hits	327	Target Neighborhood Hits	573	Shared Neighborhood Hits	59
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

LRC45_HUMAN
NC score	0.055177 (rank : 275)	θ value	1.38821 (rank : 232)
Query Neighborhood Hits	327	Target Neighborhood Hits	933	Shared Neighborhood Hits	104
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

INVO_HUMAN
NC score	0.055040 (rank : 276)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	327	Target Neighborhood Hits	636	Shared Neighborhood Hits	83
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

RGNEF_MOUSE
NC score	0.054961 (rank : 277)	θ value	6.88961 (rank : 305)
Query Neighborhood Hits	327	Target Neighborhood Hits	641	Shared Neighborhood Hits	75
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

MD1L1_MOUSE
NC score	0.054913 (rank : 278)	θ value	3.0926 (rank : 249)
Query Neighborhood Hits	327	Target Neighborhood Hits	1001	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

EZRI_MOUSE
NC score	0.054694 (rank : 279)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	327	Target Neighborhood Hits	693	Shared Neighborhood Hits	97
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

WDR67_MOUSE
NC score	0.054593 (rank : 280)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	327	Target Neighborhood Hits	476	Shared Neighborhood Hits	55
SwissProt Accessions	Q6NXY1, Q3TBW4, Q3U4F6, Q5KSA3, Q810J7, Q8C3Y2	Gene names	Wdr67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67 (Protein 4-B-3).

RADI_HUMAN
NC score	0.054428 (rank : 281)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	327	Target Neighborhood Hits	741	Shared Neighborhood Hits	101
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

NIN_HUMAN
NC score	0.054381 (rank : 282)	θ value	6.88961 (rank : 301)
Query Neighborhood Hits	327	Target Neighborhood Hits	1416	Shared Neighborhood Hits	125
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

ZN291_HUMAN
NC score	0.054380 (rank : 283)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	327	Target Neighborhood Hits	647	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

GOGA5_HUMAN
NC score	0.054373 (rank : 284)	θ value	4.03905 (rank : 259)
Query Neighborhood Hits	327	Target Neighborhood Hits	1168	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA1_MOUSE
NC score	0.054359 (rank : 285)	θ value	0.0736092 (rank : 160)
Query Neighborhood Hits	327	Target Neighborhood Hits	994	Shared Neighborhood Hits	99
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

DDIT3_HUMAN
NC score	0.054280 (rank : 286)	θ value	0.62314 (rank : 204)
Query Neighborhood Hits	327	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

AZI1_MOUSE
NC score	0.054194 (rank : 287)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	327	Target Neighborhood Hits	990	Shared Neighborhood Hits	112
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

TPR_HUMAN
NC score	0.054148 (rank : 288)	θ value	6.88961 (rank : 309)
Query Neighborhood Hits	327	Target Neighborhood Hits	1921	Shared Neighborhood Hits	145
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

LRC45_MOUSE
NC score	0.054039 (rank : 289)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	327	Target Neighborhood Hits	959	Shared Neighborhood Hits	103
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

GOGA5_MOUSE
NC score	0.053824 (rank : 290)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	327	Target Neighborhood Hits	1434	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

IF3A_MOUSE
NC score	0.053785 (rank : 291)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	327	Target Neighborhood Hits	871	Shared Neighborhood Hits	101
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

TMF1_HUMAN
NC score	0.053732 (rank : 292)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	327	Target Neighborhood Hits	987	Shared Neighborhood Hits	99
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

RADI_MOUSE
NC score	0.053517 (rank : 293)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	327	Target Neighborhood Hits	773	Shared Neighborhood Hits	102
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

CENPF_HUMAN
NC score	0.053310 (rank : 294)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	327	Target Neighborhood Hits	1932	Shared Neighborhood Hits	135
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GRAP1_MOUSE
NC score	0.053208 (rank : 295)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	327	Target Neighborhood Hits	1234	Shared Neighborhood Hits	117
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GOGB1_HUMAN
NC score	0.053125 (rank : 296)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	327	Target Neighborhood Hits	2297	Shared Neighborhood Hits	146
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HTRA2_HUMAN
NC score	0.052961 (rank : 297)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	327	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

CACB1_MOUSE
NC score	0.052931 (rank : 298)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	327	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CAF1A_MOUSE
NC score	0.052883 (rank : 299)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	327	Target Neighborhood Hits	736	Shared Neighborhood Hits	102
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCD11_MOUSE
NC score	0.052868 (rank : 300)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	327	Target Neighborhood Hits	498	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

IF3A_HUMAN
NC score	0.052828 (rank : 301)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	327	Target Neighborhood Hits	875	Shared Neighborhood Hits	101
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

CK5P2_HUMAN
NC score	0.052712 (rank : 302)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	327	Target Neighborhood Hits	1433	Shared Neighborhood Hits	116
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

RFIP4_HUMAN
NC score	0.052692 (rank : 303)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	327	Target Neighborhood Hits	785	Shared Neighborhood Hits	94
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

GOGA6_HUMAN
NC score	0.052614 (rank : 304)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	327	Target Neighborhood Hits	1007	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CCD21_HUMAN
NC score	0.052597 (rank : 305)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	327	Target Neighborhood Hits	1228	Shared Neighborhood Hits	114
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

PININ_HUMAN
NC score	0.052402 (rank : 306)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	327	Target Neighborhood Hits	753	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CCD91_MOUSE
NC score	0.052334 (rank : 307)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	327	Target Neighborhood Hits	699	Shared Neighborhood Hits	86
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

RIMS3_MOUSE
NC score	0.052310 (rank : 308)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	327	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

PREX1_HUMAN
NC score	0.052297 (rank : 309)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	327	Target Neighborhood Hits	177	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

RIMS3_HUMAN
NC score	0.052264 (rank : 310)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	327	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

HIP1_HUMAN
NC score	0.052152 (rank : 311)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	327	Target Neighborhood Hits	1016	Shared Neighborhood Hits	100
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

HMMR_HUMAN
NC score	0.052137 (rank : 312)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	327	Target Neighborhood Hits	1082	Shared Neighborhood Hits	109
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

EZRI_HUMAN
NC score	0.051960 (rank : 313)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	327	Target Neighborhood Hits	663	Shared Neighborhood Hits	95
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

CP135_MOUSE
NC score	0.051887 (rank : 314)	θ value	0.813845 (rank : 212)
Query Neighborhood Hits	327	Target Neighborhood Hits	1278	Shared Neighborhood Hits	114
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GOGA3_MOUSE
NC score	0.051613 (rank : 315)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	327	Target Neighborhood Hits	1437	Shared Neighborhood Hits	123
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MAP1A_HUMAN
NC score	0.051544 (rank : 316)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	327	Target Neighborhood Hits	1626	Shared Neighborhood Hits	117
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PIBF1_HUMAN
NC score	0.051504 (rank : 317)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	327	Target Neighborhood Hits	1041	Shared Neighborhood Hits	98
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

STAM1_MOUSE
NC score	0.051502 (rank : 318)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	327	Target Neighborhood Hits	273	Shared Neighborhood Hits	32
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

PEPL_HUMAN
NC score	0.051476 (rank : 319)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	327	Target Neighborhood Hits	1141	Shared Neighborhood Hits	115
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

IFT74_HUMAN
NC score	0.051461 (rank : 320)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	327	Target Neighborhood Hits	949	Shared Neighborhood Hits	96
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
NC score	0.051455 (rank : 321)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	327	Target Neighborhood Hits	893	Shared Neighborhood Hits	94
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

CT116_MOUSE
NC score	0.051302 (rank : 322)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	327	Target Neighborhood Hits	268	Shared Neighborhood Hits	65
SwissProt Accessions	Q80WW9, Q9CT52	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf116 homolog precursor.

WWC1_HUMAN
NC score	0.051207 (rank : 323)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	327	Target Neighborhood Hits	290	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

SDCG8_HUMAN
NC score	0.051206 (rank : 324)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	327	Target Neighborhood Hits	1002	Shared Neighborhood Hits	99
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

EEA1_HUMAN
NC score	0.051047 (rank : 325)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	327	Target Neighborhood Hits	1796	Shared Neighborhood Hits	133
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CP250_HUMAN
NC score	0.050983 (rank : 326)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	327	Target Neighborhood Hits	1805	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CCD46_HUMAN
NC score	0.050930 (rank : 327)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	327	Target Neighborhood Hits	1430	Shared Neighborhood Hits	118
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

ZWINT_MOUSE
NC score	0.050905 (rank : 328)	θ value	6.88961 (rank : 313)
Query Neighborhood Hits	327	Target Neighborhood Hits	497	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

CN145_HUMAN
NC score	0.050792 (rank : 329)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	327	Target Neighborhood Hits	1196	Shared Neighborhood Hits	117
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

NIN_MOUSE
NC score	0.050779 (rank : 330)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	327	Target Neighborhood Hits	1376	Shared Neighborhood Hits	119
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CF060_HUMAN
NC score	0.050648 (rank : 331)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	327	Target Neighborhood Hits	1270	Shared Neighborhood Hits	116
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CACB1_HUMAN
NC score	0.050625 (rank : 332)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	327	Target Neighborhood Hits	44	Shared Neighborhood Hits	19
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

GCC2_MOUSE
NC score	0.050561 (rank : 333)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	327	Target Neighborhood Hits	1619	Shared Neighborhood Hits	119
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PININ_MOUSE
NC score	0.050507 (rank : 334)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	327	Target Neighborhood Hits	777	Shared Neighborhood Hits	79
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

NUMA1_HUMAN
NC score	0.050496 (rank : 335)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	327	Target Neighborhood Hits	1523	Shared Neighborhood Hits	133
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

SWP70_MOUSE
NC score	0.050465 (rank : 336)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	327	Target Neighborhood Hits	1097	Shared Neighborhood Hits	111
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CCD41_MOUSE
NC score	0.050431 (rank : 337)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	327	Target Neighborhood Hits	1399	Shared Neighborhood Hits	115
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CACB3_MOUSE
NC score	0.050355 (rank : 338)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	327	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CACB3_HUMAN
NC score	0.050319 (rank : 339)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	327	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

IFT74_MOUSE
NC score	0.050237 (rank : 340)	θ value	5.27518 (rank : 272)
Query Neighborhood Hits	327	Target Neighborhood Hits	939	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SMC1A_HUMAN
NC score	0.050217 (rank : 341)	θ value	3.0926 (rank : 253)
Query Neighborhood Hits	327	Target Neighborhood Hits	1346	Shared Neighborhood Hits	119
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

CRK_HUMAN
NC score	0.050142 (rank : 342)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	327	Target Neighborhood Hits	308	Shared Neighborhood Hits	30
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CP135_HUMAN
NC score	0.050122 (rank : 343)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	327	Target Neighborhood Hits	1290	Shared Neighborhood Hits	116
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

EVPL_HUMAN
NC score	0.050122 (rank : 344)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	327	Target Neighborhood Hits	895	Shared Neighborhood Hits	104
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

ZC313_HUMAN
NC score	0.050106 (rank : 345)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	327	Target Neighborhood Hits	772	Shared Neighborhood Hits	79
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ARHG1_MOUSE
NC score	0.050068 (rank : 346)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	327	Target Neighborhood Hits	266	Shared Neighborhood Hits	12
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CARD9_HUMAN
NC score	0.050047 (rank : 347)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	327	Target Neighborhood Hits	602	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

LBN_HUMAN
NC score	0.050020 (rank : 348)	θ value	0.813845 (rank : 215)
Query Neighborhood Hits	327	Target Neighborhood Hits	308	Shared Neighborhood Hits	49
SwissProt Accessions	Q86UK5, Q86YT3, Q86YT4, Q8NG49	Gene names	EVC2, LBN
Domain Architecture	No domain graphic available
Description	Limbin.

MY18B_HUMAN
NC score	0.049840 (rank : 349)	θ value	1.06291 (rank : 224)
Query Neighborhood Hits	327	Target Neighborhood Hits	1299	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CEP63_HUMAN
NC score	0.049397 (rank : 350)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	327	Target Neighborhood Hits	1005	Shared Neighborhood Hits	109
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

RBP24_HUMAN
NC score	0.049226 (rank : 351)	θ value	2.36792 (rank : 246)
Query Neighborhood Hits	327	Target Neighborhood Hits	1559	Shared Neighborhood Hits	122
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.049148 (rank : 352)	θ value	2.36792 (rank : 242)
Query Neighborhood Hits	327	Target Neighborhood Hits	1558	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

SMC1A_MOUSE
NC score	0.048986 (rank : 353)	θ value	3.0926 (rank : 254)
Query Neighborhood Hits	327	Target Neighborhood Hits	1384	Shared Neighborhood Hits	121
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

GEMI_HUMAN
NC score	0.048783 (rank : 354)	θ value	1.81305 (rank : 238)
Query Neighborhood Hits	327	Target Neighborhood Hits	192	Shared Neighborhood Hits	31
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

AL2SB_HUMAN
NC score	0.048401 (rank : 355)	θ value	4.03905 (rank : 255)
Query Neighborhood Hits	327	Target Neighborhood Hits	294	Shared Neighborhood Hits	50
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

STMN4_HUMAN
NC score	0.048084 (rank : 356)	θ value	4.03905 (rank : 263)
Query Neighborhood Hits	327	Target Neighborhood Hits	395	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H169	Gene names	STMN4
Domain Architecture
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

STMN4_MOUSE
NC score	0.047689 (rank : 357)	θ value	4.03905 (rank : 264)
Query Neighborhood Hits	327	Target Neighborhood Hits	395	Shared Neighborhood Hits	52
SwissProt Accessions	P63042, O35414, O35415, O35416	Gene names	Stmn4
Domain Architecture	No domain graphic available
Description	Stathmin-4 (Stathmin-like protein B3) (RB3).

EVPL_MOUSE
NC score	0.046937 (rank : 358)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	327	Target Neighborhood Hits	952	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

EEA1_MOUSE
NC score	0.046426 (rank : 359)	θ value	5.27518 (rank : 271)
Query Neighborhood Hits	327	Target Neighborhood Hits	1637	Shared Neighborhood Hits	125
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

NUCB1_MOUSE
NC score	0.046191 (rank : 360)	θ value	3.0926 (rank : 251)
Query Neighborhood Hits	327	Target Neighborhood Hits	414	Shared Neighborhood Hits	65
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

CT2NL_HUMAN
NC score	0.045338 (rank : 361)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	327	Target Neighborhood Hits	1059	Shared Neighborhood Hits	99
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ANR26_HUMAN
NC score	0.045261 (rank : 362)	θ value	0.47712 (rank : 196)
Query Neighborhood Hits	327	Target Neighborhood Hits	1614	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GEMI_MOUSE
NC score	0.044089 (rank : 363)	θ value	4.03905 (rank : 258)
Query Neighborhood Hits	327	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	O88513	Gene names	Gmnn
Domain Architecture
Description	Geminin.

NUCB1_HUMAN
NC score	0.044009 (rank : 364)	θ value	3.0926 (rank : 250)
Query Neighborhood Hits	327	Target Neighborhood Hits	359	Shared Neighborhood Hits	51
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

LIMK1_HUMAN
NC score	0.043054 (rank : 365)	θ value	0.47712 (rank : 198)
Query Neighborhood Hits	327	Target Neighborhood Hits	1005	Shared Neighborhood Hits	88
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

CS029_HUMAN
NC score	0.041936 (rank : 366)	θ value	3.0926 (rank : 247)
Query Neighborhood Hits	327	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

LIMK1_MOUSE
NC score	0.041171 (rank : 367)	θ value	0.47712 (rank : 199)
Query Neighborhood Hits	327	Target Neighborhood Hits	1008	Shared Neighborhood Hits	88
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

MYO5C_HUMAN
NC score	0.041064 (rank : 368)	θ value	0.813845 (rank : 216)
Query Neighborhood Hits	327	Target Neighborhood Hits	1206	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

ASPP2_HUMAN
NC score	0.040573 (rank : 369)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	327	Target Neighborhood Hits	1156	Shared Neighborhood Hits	100
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

TPM4_MOUSE
NC score	0.040346 (rank : 370)	θ value	6.88961 (rank : 308)
Query Neighborhood Hits	327	Target Neighborhood Hits	703	Shared Neighborhood Hits	82
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

UACA_HUMAN
NC score	0.040076 (rank : 371)	θ value	5.27518 (rank : 283)
Query Neighborhood Hits	327	Target Neighborhood Hits	1622	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

GBP5_MOUSE
NC score	0.039275 (rank : 372)	θ value	0.813845 (rank : 214)
Query Neighborhood Hits	327	Target Neighborhood Hits	254	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

STIM1_HUMAN
NC score	0.038989 (rank : 373)	θ value	5.27518 (rank : 280)
Query Neighborhood Hits	327	Target Neighborhood Hits	665	Shared Neighborhood Hits	80
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

NTBP1_MOUSE
NC score	0.038881 (rank : 374)	θ value	6.88961 (rank : 303)
Query Neighborhood Hits	327	Target Neighborhood Hits	528	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

MYH9_MOUSE
NC score	0.038518 (rank : 375)	θ value	6.88961 (rank : 300)
Query Neighborhood Hits	327	Target Neighborhood Hits	1829	Shared Neighborhood Hits	127
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ASPP1_MOUSE
NC score	0.038081 (rank : 376)	θ value	1.81305 (rank : 237)
Query Neighborhood Hits	327	Target Neighborhood Hits	1244	Shared Neighborhood Hits	77
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MYH11_HUMAN
NC score	0.037983 (rank : 377)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	327	Target Neighborhood Hits	1806	Shared Neighborhood Hits	133
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

STIM1_MOUSE
NC score	0.037922 (rank : 378)	θ value	5.27518 (rank : 281)
Query Neighborhood Hits	327	Target Neighborhood Hits	660	Shared Neighborhood Hits	79
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

K0831_MOUSE
NC score	0.036705 (rank : 379)	θ value	2.36792 (rank : 244)
Query Neighborhood Hits	327	Target Neighborhood Hits	277	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

BPAEA_HUMAN
NC score	0.036405 (rank : 380)	θ value	1.06291 (rank : 221)
Query Neighborhood Hits	327	Target Neighborhood Hits	1369	Shared Neighborhood Hits	104
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MLL2_HUMAN
NC score	0.034124 (rank : 381)	θ value	4.03905 (rank : 261)
Query Neighborhood Hits	327	Target Neighborhood Hits	1788	Shared Neighborhood Hits	101
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ASPP1_HUMAN
NC score	0.034037 (rank : 382)	θ value	4.03905 (rank : 256)
Query Neighborhood Hits	327	Target Neighborhood Hits	956	Shared Neighborhood Hits	72
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

SKI_MOUSE
NC score	0.033041 (rank : 383)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	327	Target Neighborhood Hits	423	Shared Neighborhood Hits	59
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

PLCB1_MOUSE
NC score	0.032663 (rank : 384)	θ value	5.27518 (rank : 279)
Query Neighborhood Hits	327	Target Neighborhood Hits	531	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SVIL_MOUSE
NC score	0.032399 (rank : 385)	θ value	0.0330416 (rank : 155)
Query Neighborhood Hits	327	Target Neighborhood Hits	439	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

MRCKB_HUMAN
NC score	0.031970 (rank : 386)	θ value	0.365318 (rank : 194)
Query Neighborhood Hits	327	Target Neighborhood Hits	2239	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

STK10_MOUSE
NC score	0.031866 (rank : 387)	θ value	0.163984 (rank : 182)
Query Neighborhood Hits	327	Target Neighborhood Hits	2132	Shared Neighborhood Hits	124
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TAOK1_HUMAN
NC score	0.031108 (rank : 388)	θ value	0.00298849 (rank : 116)
Query Neighborhood Hits	327	Target Neighborhood Hits	1734	Shared Neighborhood Hits	113
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TAOK1_MOUSE
NC score	0.030384 (rank : 389)	θ value	0.00665767 (rank : 133)
Query Neighborhood Hits	327	Target Neighborhood Hits	1720	Shared Neighborhood Hits	114
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

KI21A_HUMAN
NC score	0.030205 (rank : 390)	θ value	3.0926 (rank : 248)
Query Neighborhood Hits	327	Target Neighborhood Hits	1543	Shared Neighborhood Hits	113
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

ZN318_MOUSE
NC score	0.026947 (rank : 391)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	327	Target Neighborhood Hits	642	Shared Neighborhood Hits	53
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

LMNB2_HUMAN
NC score	0.026378 (rank : 392)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	327	Target Neighborhood Hits	723	Shared Neighborhood Hits	82
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

DTNA_HUMAN
NC score	0.026325 (rank : 393)	θ value	5.27518 (rank : 270)
Query Neighborhood Hits	327	Target Neighborhood Hits	295	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y4J8, O15332, O15333, O75697, Q13197, Q13198, Q13199, Q13498, Q13499, Q13500	Gene names	DTNA, DRP3
Domain Architecture
Description	Dystrobrevin alpha (Dystrobrevin-alpha) (Dystrophin-related protein 3).

MLL3_HUMAN
NC score	0.026140 (rank : 394)	θ value	5.27518 (rank : 274)
Query Neighborhood Hits	327	Target Neighborhood Hits	1644	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MPP8_HUMAN
NC score	0.024815 (rank : 395)	θ value	2.36792 (rank : 245)
Query Neighborhood Hits	327	Target Neighborhood Hits	948	Shared Neighborhood Hits	54
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

DTNB_MOUSE
NC score	0.024814 (rank : 396)	θ value	4.03905 (rank : 257)
Query Neighborhood Hits	327	Target Neighborhood Hits	263	Shared Neighborhood Hits	38
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

SLK_HUMAN
NC score	0.023513 (rank : 397)	θ value	3.0926 (rank : 252)
Query Neighborhood Hits	327	Target Neighborhood Hits	1775	Shared Neighborhood Hits	123
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
NC score	0.023414 (rank : 398)	θ value	1.81305 (rank : 241)
Query Neighborhood Hits	327	Target Neighborhood Hits	1798	Shared Neighborhood Hits	127
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

KIF14_HUMAN
NC score	0.023361 (rank : 399)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	327	Target Neighborhood Hits	732	Shared Neighborhood Hits	85
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

MCF2_HUMAN
NC score	0.023185 (rank : 400)	θ value	5.27518 (rank : 273)
Query Neighborhood Hits	327	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P10911, P14919, Q5JYJ4, Q8IUF3, Q8IUF4, Q9UJB3	Gene names	MCF2, DBL
Domain Architecture
Description	Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2-transforming protein; DBL-transforming protein].

XRCC4_HUMAN
NC score	0.022379 (rank : 401)	θ value	1.38821 (rank : 236)
Query Neighborhood Hits	327	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

KLC1_HUMAN
NC score	0.021689 (rank : 402)	θ value	1.81305 (rank : 239)
Query Neighborhood Hits	327	Target Neighborhood Hits	471	Shared Neighborhood Hits	57
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

PPIP1_MOUSE
NC score	0.021267 (rank : 403)	θ value	6.88961 (rank : 304)
Query Neighborhood Hits	327	Target Neighborhood Hits	377	Shared Neighborhood Hits	52
SwissProt Accessions	P97814, Q4V9R4	Gene names	Pstpip1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1).

TRI39_MOUSE
NC score	0.020401 (rank : 404)	θ value	6.88961 (rank : 310)
Query Neighborhood Hits	327	Target Neighborhood Hits	691	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_HUMAN
NC score	0.018974 (rank : 405)	θ value	8.99809 (rank : 326)
Query Neighborhood Hits	327	Target Neighborhood Hits	693	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

CEBPE_HUMAN
NC score	0.017421 (rank : 406)	θ value	5.27518 (rank : 269)
Query Neighborhood Hits	327	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

KRHB6_HUMAN
NC score	0.014095 (rank : 407)	θ value	6.88961 (rank : 294)
Query Neighborhood Hits	327	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

KRHB1_HUMAN
NC score	0.014020 (rank : 408)	θ value	6.88961 (rank : 293)
Query Neighborhood Hits	327	Target Neighborhood Hits	461	Shared Neighborhood Hits	54
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB6_MOUSE
NC score	0.013826 (rank : 409)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	327	Target Neighborhood Hits	413	Shared Neighborhood Hits	59
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

NOL3_MOUSE
NC score	0.010790 (rank : 410)	θ value	6.88961 (rank : 302)
Query Neighborhood Hits	327	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

KRHB5_MOUSE
NC score	0.010548 (rank : 411)	θ value	4.03905 (rank : 260)
Query Neighborhood Hits	327	Target Neighborhood Hits	294	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z2T6, Q8CE83, Q9D7M4	Gene names	Krthb5, Krt2-18
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

ZCH12_MOUSE
NC score	0.008911 (rank : 412)	θ value	8.99809 (rank : 327)
Query Neighborhood Hits	327	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZA5	Gene names	Zcchc12, Sizn
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 12 (Smad-interacting zinc finger protein).

MYSM1_MOUSE
NC score	0.008666 (rank : 413)	θ value	5.27518 (rank : 276)
Query Neighborhood Hits	327	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q69Z66, Q3TPV7, Q8BRP5, Q8C4N1	Gene names	Mysm1, Kiaa1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

NEK11_HUMAN
NC score	0.007361 (rank : 414)	θ value	5.27518 (rank : 277)
Query Neighborhood Hits	327	Target Neighborhood Hits	1043	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

TLK1_HUMAN
NC score	0.005488 (rank : 415)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	327	Target Neighborhood Hits	967	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

PDE6C_HUMAN
NC score	0.004276 (rank : 416)	θ value	5.27518 (rank : 278)
Query Neighborhood Hits	327	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

CO4A4_HUMAN
NC score	0.002525 (rank : 417)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	327	Target Neighborhood Hits	440	Shared Neighborhood Hits	16
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

TBG1_MOUSE
NC score	0.002080 (rank : 418)	θ value	5.27518 (rank : 282)
Query Neighborhood Hits	327	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P83887, Q9Z310	Gene names	Tubg1, Tubg
Domain Architecture
Description	Tubulin gamma-1 chain (Gamma-1 tubulin) (Gamma-tubulin complex component 1) (GCP-1).

TIE2_HUMAN
NC score	-0.003537 (rank : 419)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	327	Target Neighborhood Hits	1192	Shared Neighborhood Hits	20
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

ZN710_HUMAN
NC score	-0.010444 (rank : 420)	θ value	6.88961 (rank : 311)
Query Neighborhood Hits	327	Target Neighborhood Hits	796	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ZNF16_HUMAN
NC score	-0.010520 (rank : 421)	θ value	6.88961 (rank : 312)
Query Neighborhood Hits	327	Target Neighborhood Hits	771	Shared Neighborhood Hits	4
SwissProt Accessions	P17020, Q96FG0	Gene names	ZNF16, KOX9
Domain Architecture	No domain graphic available
Description	Zinc finger protein 16 (Zinc finger protein KOX9).