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Network neighborhood for query Sequence : RGS12_HUMAN

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RGS12_HUMAN
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RGS12_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	333	Target Neighborhood Hits	333	Shared Neighborhood Hits	333
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS14_MOUSE
θ value	3.00772e-96 (rank : 2)	NC score	0.862180 (rank : 2)
Query Neighborhood Hits	333	Target Neighborhood Hits	55	Shared Neighborhood Hits	44
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS14_HUMAN
θ value	6.27148e-94 (rank : 3)	NC score	0.859969 (rank : 3)
Query Neighborhood Hits	333	Target Neighborhood Hits	77	Shared Neighborhood Hits	47
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS10_HUMAN
θ value	2.50655e-34 (rank : 4)	NC score	0.825553 (rank : 5)
Query Neighborhood Hits	333	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS10_MOUSE
θ value	2.12192e-33 (rank : 5)	NC score	0.825746 (rank : 4)
Query Neighborhood Hits	333	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS9_MOUSE
θ value	2.69047e-20 (rank : 6)	NC score	0.723600 (rank : 29)
Query Neighborhood Hits	333	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS11_HUMAN
θ value	3.51386e-20 (rank : 7)	NC score	0.737060 (rank : 28)
Query Neighborhood Hits	333	Target Neighborhood Hits	68	Shared Neighborhood Hits	48
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS17_HUMAN
θ value	7.82807e-20 (rank : 8)	NC score	0.773650 (rank : 7)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS19_MOUSE
θ value	1.02238e-19 (rank : 9)	NC score	0.774230 (rank : 6)
Query Neighborhood Hits	333	Target Neighborhood Hits	46	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS4_HUMAN
θ value	1.02238e-19 (rank : 10)	NC score	0.771574 (rank : 10)
Query Neighborhood Hits	333	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS7_MOUSE
θ value	1.02238e-19 (rank : 11)	NC score	0.717752 (rank : 31)
Query Neighborhood Hits	333	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS9_HUMAN
θ value	1.02238e-19 (rank : 12)	NC score	0.722612 (rank : 30)
Query Neighborhood Hits	333	Target Neighborhood Hits	64	Shared Neighborhood Hits	45
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS4_MOUSE
θ value	1.33526e-19 (rank : 13)	NC score	0.772362 (rank : 9)
Query Neighborhood Hits	333	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS17_MOUSE
θ value	1.74391e-19 (rank : 14)	NC score	0.772980 (rank : 8)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS7_HUMAN
θ value	5.07402e-19 (rank : 15)	NC score	0.717733 (rank : 32)
Query Neighborhood Hits	333	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS19_HUMAN
θ value	8.65492e-19 (rank : 16)	NC score	0.770604 (rank : 14)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS1_HUMAN
θ value	2.5182e-18 (rank : 17)	NC score	0.771512 (rank : 11)
Query Neighborhood Hits	333	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS6_MOUSE
θ value	4.29542e-18 (rank : 18)	NC score	0.713495 (rank : 33)
Query Neighborhood Hits	333	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS16_HUMAN
θ value	7.32683e-18 (rank : 19)	NC score	0.762922 (rank : 19)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS20_MOUSE
θ value	2.7842e-17 (rank : 20)	NC score	0.771052 (rank : 13)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS1_MOUSE
θ value	3.63628e-17 (rank : 21)	NC score	0.771135 (rank : 12)
Query Neighborhood Hits	333	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS3_HUMAN
θ value	4.74913e-17 (rank : 22)	NC score	0.596909 (rank : 35)
Query Neighborhood Hits	333	Target Neighborhood Hits	1375	Shared Neighborhood Hits	183
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RGS3_MOUSE
θ value	4.74913e-17 (rank : 23)	NC score	0.542439 (rank : 37)
Query Neighborhood Hits	333	Target Neighborhood Hits	1621	Shared Neighborhood Hits	192
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RGS16_MOUSE
θ value	6.20254e-17 (rank : 24)	NC score	0.761297 (rank : 21)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS20_HUMAN
θ value	8.10077e-17 (rank : 25)	NC score	0.767388 (rank : 16)
Query Neighborhood Hits	333	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS18_MOUSE
θ value	1.80466e-16 (rank : 26)	NC score	0.760951 (rank : 23)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS8_HUMAN
θ value	1.80466e-16 (rank : 27)	NC score	0.764217 (rank : 17)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS18_HUMAN
θ value	2.35696e-16 (rank : 28)	NC score	0.762048 (rank : 20)
Query Neighborhood Hits	333	Target Neighborhood Hits	44	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS8_MOUSE
θ value	2.35696e-16 (rank : 29)	NC score	0.763735 (rank : 18)
Query Neighborhood Hits	333	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS6_HUMAN
θ value	6.85773e-16 (rank : 30)	NC score	0.693910 (rank : 34)
Query Neighborhood Hits	333	Target Neighborhood Hits	80	Shared Neighborhood Hits	43
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

RGS2_MOUSE
θ value	1.99529e-15 (rank : 31)	NC score	0.752295 (rank : 27)
Query Neighborhood Hits	333	Target Neighborhood Hits	52	Shared Neighborhood Hits	43
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS5_MOUSE
θ value	2.60593e-15 (rank : 32)	NC score	0.769386 (rank : 15)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	45
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS2_HUMAN
θ value	4.44505e-15 (rank : 33)	NC score	0.752840 (rank : 26)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	43
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS5_HUMAN
θ value	4.91457e-14 (rank : 34)	NC score	0.761257 (rank : 22)
Query Neighborhood Hits	333	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS13_MOUSE
θ value	2.43908e-13 (rank : 35)	NC score	0.755173 (rank : 25)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS13_HUMAN
θ value	7.09661e-13 (rank : 36)	NC score	0.756063 (rank : 24)
Query Neighborhood Hits	333	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

NHRF2_HUMAN
θ value	6.87365e-08 (rank : 37)	NC score	0.362970 (rank : 41)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	126
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

AXN1_MOUSE
θ value	1.99992e-07 (rank : 38)	NC score	0.543099 (rank : 36)
Query Neighborhood Hits	333	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

NHRF2_MOUSE
θ value	4.45536e-07 (rank : 39)	NC score	0.357498 (rank : 42)
Query Neighborhood Hits	333	Target Neighborhood Hits	194	Shared Neighborhood Hits	126
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

DLG4_HUMAN
θ value	2.21117e-06 (rank : 40)	NC score	0.291400 (rank : 75)
Query Neighborhood Hits	333	Target Neighborhood Hits	286	Shared Neighborhood Hits	130
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	2.21117e-06 (rank : 41)	NC score	0.291836 (rank : 74)
Query Neighborhood Hits	333	Target Neighborhood Hits	282	Shared Neighborhood Hits	131
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

MAGI1_MOUSE
θ value	2.88788e-06 (rank : 42)	NC score	0.305228 (rank : 64)
Query Neighborhood Hits	333	Target Neighborhood Hits	403	Shared Neighborhood Hits	141
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

RHPN1_MOUSE
θ value	4.92598e-06 (rank : 43)	NC score	0.280798 (rank : 92)
Query Neighborhood Hits	333	Target Neighborhood Hits	154	Shared Neighborhood Hits	116
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

AXN1_HUMAN
θ value	6.43352e-06 (rank : 44)	NC score	0.526789 (rank : 38)
Query Neighborhood Hits	333	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

AXN2_HUMAN
θ value	1.43324e-05 (rank : 45)	NC score	0.513123 (rank : 39)
Query Neighborhood Hits	333	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

LIN7C_HUMAN
θ value	1.43324e-05 (rank : 46)	NC score	0.345424 (rank : 48)
Query Neighborhood Hits	333	Target Neighborhood Hits	198	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	1.43324e-05 (rank : 47)	NC score	0.345424 (rank : 49)
Query Neighborhood Hits	333	Target Neighborhood Hits	198	Shared Neighborhood Hits	134
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

NHERF_MOUSE
θ value	1.43324e-05 (rank : 48)	NC score	0.353380 (rank : 44)
Query Neighborhood Hits	333	Target Neighborhood Hits	195	Shared Neighborhood Hits	125
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD1_HUMAN
θ value	1.43324e-05 (rank : 49)	NC score	0.351492 (rank : 45)
Query Neighborhood Hits	333	Target Neighborhood Hits	190	Shared Neighborhood Hits	125
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

DLG1_HUMAN
θ value	1.87187e-05 (rank : 50)	NC score	0.286791 (rank : 79)
Query Neighborhood Hits	333	Target Neighborhood Hits	290	Shared Neighborhood Hits	126
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
θ value	1.87187e-05 (rank : 51)	NC score	0.286169 (rank : 81)
Query Neighborhood Hits	333	Target Neighborhood Hits	285	Shared Neighborhood Hits	127
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG3_HUMAN
θ value	1.87187e-05 (rank : 52)	NC score	0.284089 (rank : 86)
Query Neighborhood Hits	333	Target Neighborhood Hits	269	Shared Neighborhood Hits	127
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
θ value	1.87187e-05 (rank : 53)	NC score	0.285311 (rank : 83)
Query Neighborhood Hits	333	Target Neighborhood Hits	274	Shared Neighborhood Hits	126
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

NHERF_HUMAN
θ value	1.87187e-05 (rank : 54)	NC score	0.353478 (rank : 43)
Query Neighborhood Hits	333	Target Neighborhood Hits	190	Shared Neighborhood Hits	128
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

RHPN1_HUMAN
θ value	1.87187e-05 (rank : 55)	NC score	0.266395 (rank : 102)
Query Neighborhood Hits	333	Target Neighborhood Hits	158	Shared Neighborhood Hits	113
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SNX13_MOUSE
θ value	1.87187e-05 (rank : 56)	NC score	0.288621 (rank : 76)
Query Neighborhood Hits	333	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

LIN7B_HUMAN
θ value	2.44474e-05 (rank : 57)	NC score	0.344941 (rank : 51)
Query Neighborhood Hits	333	Target Neighborhood Hits	200	Shared Neighborhood Hits	133
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

MAGI1_HUMAN
θ value	2.44474e-05 (rank : 58)	NC score	0.298534 (rank : 71)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	141
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

LIN7B_MOUSE
θ value	3.19293e-05 (rank : 59)	NC score	0.344173 (rank : 52)
Query Neighborhood Hits	333	Target Neighborhood Hits	200	Shared Neighborhood Hits	133
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

ARHGB_HUMAN
θ value	4.1701e-05 (rank : 60)	NC score	0.206174 (rank : 120)
Query Neighborhood Hits	333	Target Neighborhood Hits	375	Shared Neighborhood Hits	144
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

AXN2_MOUSE
θ value	5.44631e-05 (rank : 61)	NC score	0.502127 (rank : 40)
Query Neighborhood Hits	333	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

DLG2_HUMAN
θ value	5.44631e-05 (rank : 62)	NC score	0.282003 (rank : 90)
Query Neighborhood Hits	333	Target Neighborhood Hits	279	Shared Neighborhood Hits	128
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

DLG2_MOUSE
θ value	5.44631e-05 (rank : 63)	NC score	0.282800 (rank : 88)
Query Neighborhood Hits	333	Target Neighborhood Hits	271	Shared Neighborhood Hits	127
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

WHRN_HUMAN
θ value	7.1131e-05 (rank : 64)	NC score	0.331961 (rank : 53)
Query Neighborhood Hits	333	Target Neighborhood Hits	325	Shared Neighborhood Hits	147
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
θ value	7.1131e-05 (rank : 65)	NC score	0.331810 (rank : 54)
Query Neighborhood Hits	333	Target Neighborhood Hits	412	Shared Neighborhood Hits	151
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD1_MOUSE
θ value	9.29e-05 (rank : 66)	NC score	0.346596 (rank : 46)
Query Neighborhood Hits	333	Target Neighborhood Hits	191	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

SNX13_HUMAN
θ value	9.29e-05 (rank : 67)	NC score	0.282052 (rank : 89)
Query Neighborhood Hits	333	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

MPDZ_HUMAN
θ value	0.000158464 (rank : 68)	NC score	0.302840 (rank : 67)
Query Neighborhood Hits	333	Target Neighborhood Hits	261	Shared Neighborhood Hits	133
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

GRIP2_HUMAN
θ value	0.000270298 (rank : 69)	NC score	0.310523 (rank : 59)
Query Neighborhood Hits	333	Target Neighborhood Hits	256	Shared Neighborhood Hits	136
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

MPDZ_MOUSE
θ value	0.000270298 (rank : 70)	NC score	0.302463 (rank : 68)
Query Neighborhood Hits	333	Target Neighborhood Hits	298	Shared Neighborhood Hits	135
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

GRIP1_HUMAN
θ value	0.00035302 (rank : 71)	NC score	0.305333 (rank : 63)
Query Neighborhood Hits	333	Target Neighborhood Hits	231	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GRIP1_MOUSE
θ value	0.00035302 (rank : 72)	NC score	0.304968 (rank : 65)
Query Neighborhood Hits	333	Target Neighborhood Hits	241	Shared Neighborhood Hits	136
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

LIN7A_HUMAN
θ value	0.000461057 (rank : 73)	NC score	0.345204 (rank : 50)
Query Neighborhood Hits	333	Target Neighborhood Hits	193	Shared Neighborhood Hits	133
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	0.000461057 (rank : 74)	NC score	0.345521 (rank : 47)
Query Neighborhood Hits	333	Target Neighborhood Hits	193	Shared Neighborhood Hits	133
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

INADL_HUMAN
θ value	0.000602161 (rank : 75)	NC score	0.303124 (rank : 66)
Query Neighborhood Hits	333	Target Neighborhood Hits	260	Shared Neighborhood Hits	132
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

GOPC_HUMAN
θ value	0.000786445 (rank : 76)	NC score	0.295722 (rank : 73)
Query Neighborhood Hits	333	Target Neighborhood Hits	377	Shared Neighborhood Hits	121
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

INADL_MOUSE
θ value	0.000786445 (rank : 77)	NC score	0.307525 (rank : 60)
Query Neighborhood Hits	333	Target Neighborhood Hits	290	Shared Neighborhood Hits	136
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LAP4_HUMAN
θ value	0.000786445 (rank : 78)	NC score	0.196366 (rank : 129)
Query Neighborhood Hits	333	Target Neighborhood Hits	608	Shared Neighborhood Hits	148
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

ARHGC_HUMAN
θ value	0.00102713 (rank : 79)	NC score	0.186210 (rank : 136)
Query Neighborhood Hits	333	Target Neighborhood Hits	351	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ARHGC_MOUSE
θ value	0.00102713 (rank : 80)	NC score	0.187209 (rank : 134)
Query Neighborhood Hits	333	Target Neighborhood Hits	344	Shared Neighborhood Hits	124
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

GOPC_MOUSE
θ value	0.00134147 (rank : 81)	NC score	0.299419 (rank : 70)
Query Neighborhood Hits	333	Target Neighborhood Hits	323	Shared Neighborhood Hits	120
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PDZD3_MOUSE
θ value	0.00228821 (rank : 82)	NC score	0.319114 (rank : 56)
Query Neighborhood Hits	333	Target Neighborhood Hits	171	Shared Neighborhood Hits	118
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

PTN13_HUMAN
θ value	0.00228821 (rank : 83)	NC score	0.175228 (rank : 145)
Query Neighborhood Hits	333	Target Neighborhood Hits	471	Shared Neighborhood Hits	137
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SNTG1_MOUSE
θ value	0.00228821 (rank : 84)	NC score	0.286221 (rank : 80)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	128
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTG1_HUMAN
θ value	0.00298849 (rank : 85)	NC score	0.285164 (rank : 84)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

ZN687_HUMAN
θ value	0.00298849 (rank : 86)	NC score	0.022332 (rank : 335)
Query Neighborhood Hits	333	Target Neighborhood Hits	1244	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AKA10_MOUSE
θ value	0.00390308 (rank : 87)	NC score	0.286869 (rank : 78)
Query Neighborhood Hits	333	Target Neighborhood Hits	75	Shared Neighborhood Hits	37
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

SNTB2_HUMAN
θ value	0.00390308 (rank : 88)	NC score	0.285887 (rank : 82)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	120
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

USH1C_HUMAN
θ value	0.00390308 (rank : 89)	NC score	0.318165 (rank : 57)
Query Neighborhood Hits	333	Target Neighborhood Hits	327	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.00390308 (rank : 90)	NC score	0.302436 (rank : 69)
Query Neighborhood Hits	333	Target Neighborhood Hits	557	Shared Neighborhood Hits	146
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ZO3_HUMAN
θ value	0.00509761 (rank : 91)	NC score	0.239807 (rank : 110)
Query Neighborhood Hits	333	Target Neighborhood Hits	219	Shared Neighborhood Hits	132
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

CYLC2_HUMAN
θ value	0.00665767 (rank : 92)	NC score	0.054969 (rank : 262)
Query Neighborhood Hits	333	Target Neighborhood Hits	223	Shared Neighborhood Hits	16
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

SNTB2_MOUSE
θ value	0.00665767 (rank : 93)	NC score	0.284725 (rank : 85)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	118
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTG2_MOUSE
θ value	0.00665767 (rank : 94)	NC score	0.276899 (rank : 94)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	126
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

PDLI3_MOUSE
θ value	0.00869519 (rank : 95)	NC score	0.164559 (rank : 151)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	92
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

SYP2L_HUMAN
θ value	0.00869519 (rank : 96)	NC score	0.225880 (rank : 115)
Query Neighborhood Hits	333	Target Neighborhood Hits	400	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

APBA2_HUMAN
θ value	0.0113563 (rank : 97)	NC score	0.198958 (rank : 128)
Query Neighborhood Hits	333	Target Neighborhood Hits	220	Shared Neighborhood Hits	110
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.0113563 (rank : 98)	NC score	0.202367 (rank : 125)
Query Neighborhood Hits	333	Target Neighborhood Hits	219	Shared Neighborhood Hits	115
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

AKA10_HUMAN
θ value	0.0148317 (rank : 99)	NC score	0.283339 (rank : 87)
Query Neighborhood Hits	333	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

APBA1_HUMAN
θ value	0.0148317 (rank : 100)	NC score	0.207607 (rank : 119)
Query Neighborhood Hits	333	Target Neighborhood Hits	325	Shared Neighborhood Hits	128
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

PDLI5_HUMAN
θ value	0.0148317 (rank : 101)	NC score	0.126649 (rank : 180)
Query Neighborhood Hits	333	Target Neighborhood Hits	322	Shared Neighborhood Hits	115
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SNTG2_HUMAN
θ value	0.0148317 (rank : 102)	NC score	0.286970 (rank : 77)
Query Neighborhood Hits	333	Target Neighborhood Hits	191	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SYNP2_MOUSE
θ value	0.0148317 (rank : 103)	NC score	0.195940 (rank : 130)
Query Neighborhood Hits	333	Target Neighborhood Hits	252	Shared Neighborhood Hits	115
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

DP13A_HUMAN
θ value	0.0193708 (rank : 104)	NC score	0.048407 (rank : 280)
Query Neighborhood Hits	333	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

PDLI2_MOUSE
θ value	0.0193708 (rank : 105)	NC score	0.209404 (rank : 118)
Query Neighborhood Hits	333	Target Neighborhood Hits	220	Shared Neighborhood Hits	110
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

PDZD3_HUMAN
θ value	0.0193708 (rank : 106)	NC score	0.320356 (rank : 55)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

DP13A_MOUSE
θ value	0.0252991 (rank : 107)	NC score	0.048343 (rank : 281)
Query Neighborhood Hits	333	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

PARD3_MOUSE
θ value	0.0252991 (rank : 108)	NC score	0.268924 (rank : 97)
Query Neighborhood Hits	333	Target Neighborhood Hits	290	Shared Neighborhood Hits	120
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PTN13_MOUSE
θ value	0.0252991 (rank : 109)	NC score	0.171416 (rank : 147)
Query Neighborhood Hits	333	Target Neighborhood Hits	426	Shared Neighborhood Hits	136
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

SNTB1_MOUSE
θ value	0.0252991 (rank : 110)	NC score	0.268309 (rank : 99)
Query Neighborhood Hits	333	Target Neighborhood Hits	160	Shared Neighborhood Hits	117
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

MTMR7_MOUSE
θ value	0.0330416 (rank : 111)	NC score	0.027274 (rank : 323)
Query Neighborhood Hits	333	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

PARD3_HUMAN
θ value	0.0330416 (rank : 112)	NC score	0.266687 (rank : 101)
Query Neighborhood Hits	333	Target Neighborhood Hits	312	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

ZN167_HUMAN
θ value	0.0330416 (rank : 113)	NC score	-0.004864 (rank : 403)
Query Neighborhood Hits	333	Target Neighborhood Hits	784	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0L1, Q6WL09, Q96FQ2	Gene names	ZNF167, ZNF448, ZNF64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 167 (Zinc finger protein 64) (Zinc finger protein 448) (ZFP).

ZO3_MOUSE
θ value	0.0330416 (rank : 114)	NC score	0.243784 (rank : 106)
Query Neighborhood Hits	333	Target Neighborhood Hits	224	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

CO4A1_MOUSE
θ value	0.0431538 (rank : 115)	NC score	0.066088 (rank : 229)
Query Neighborhood Hits	333	Target Neighborhood Hits	450	Shared Neighborhood Hits	68
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

GRASP_HUMAN
θ value	0.0431538 (rank : 116)	NC score	0.243285 (rank : 107)
Query Neighborhood Hits	333	Target Neighborhood Hits	147	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
θ value	0.0431538 (rank : 117)	NC score	0.242365 (rank : 108)
Query Neighborhood Hits	333	Target Neighborhood Hits	131	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

MAGI2_HUMAN
θ value	0.0431538 (rank : 118)	NC score	0.281813 (rank : 91)
Query Neighborhood Hits	333	Target Neighborhood Hits	373	Shared Neighborhood Hits	145
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	0.0431538 (rank : 119)	NC score	0.278789 (rank : 93)
Query Neighborhood Hits	333	Target Neighborhood Hits	370	Shared Neighborhood Hits	144
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

PDZ11_MOUSE
θ value	0.0431538 (rank : 120)	NC score	0.307239 (rank : 61)
Query Neighborhood Hits	333	Target Neighborhood Hits	154	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SNTA1_HUMAN
θ value	0.0431538 (rank : 121)	NC score	0.268887 (rank : 98)
Query Neighborhood Hits	333	Target Neighborhood Hits	186	Shared Neighborhood Hits	129
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTA1_MOUSE
θ value	0.0563607 (rank : 122)	NC score	0.267475 (rank : 100)
Query Neighborhood Hits	333	Target Neighborhood Hits	170	Shared Neighborhood Hits	125
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

MUC1_HUMAN
θ value	0.0736092 (rank : 123)	NC score	0.064382 (rank : 231)
Query Neighborhood Hits	333	Target Neighborhood Hits	975	Shared Neighborhood Hits	91
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NFH_MOUSE
θ value	0.0736092 (rank : 124)	NC score	0.036367 (rank : 301)
Query Neighborhood Hits	333	Target Neighborhood Hits	2247	Shared Neighborhood Hits	128
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PDLI5_MOUSE
θ value	0.0736092 (rank : 125)	NC score	0.122867 (rank : 187)
Query Neighborhood Hits	333	Target Neighborhood Hits	287	Shared Neighborhood Hits	110
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

SNTB1_HUMAN
θ value	0.0736092 (rank : 126)	NC score	0.265602 (rank : 103)
Query Neighborhood Hits	333	Target Neighborhood Hits	157	Shared Neighborhood Hits	117
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

CO3A1_HUMAN
θ value	0.0961366 (rank : 127)	NC score	0.075529 (rank : 218)
Query Neighborhood Hits	333	Target Neighborhood Hits	452	Shared Neighborhood Hits	60
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

NOS1_MOUSE
θ value	0.0961366 (rank : 128)	NC score	0.126579 (rank : 181)
Query Neighborhood Hits	333	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PDLI3_HUMAN
θ value	0.0961366 (rank : 129)	NC score	0.168723 (rank : 149)
Query Neighborhood Hits	333	Target Neighborhood Hits	199	Shared Neighborhood Hits	96
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

PDZ11_HUMAN
θ value	0.0961366 (rank : 130)	NC score	0.306534 (rank : 62)
Query Neighborhood Hits	333	Target Neighborhood Hits	160	Shared Neighborhood Hits	120
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

CN032_MOUSE
θ value	0.125558 (rank : 131)	NC score	0.071846 (rank : 223)
Query Neighborhood Hits	333	Target Neighborhood Hits	233	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CO3A1_MOUSE
θ value	0.163984 (rank : 132)	NC score	0.073749 (rank : 220)
Query Neighborhood Hits	333	Target Neighborhood Hits	466	Shared Neighborhood Hits	61
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

GPSM1_MOUSE
θ value	0.163984 (rank : 133)	NC score	0.043762 (rank : 288)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IR34, Q61366, Q8BUK4, Q8BX78, Q8R0R9	Gene names	Gpsm1, Ags3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

LAP4_MOUSE
θ value	0.163984 (rank : 134)	NC score	0.188391 (rank : 133)
Query Neighborhood Hits	333	Target Neighborhood Hits	590	Shared Neighborhood Hits	145
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LMO7_HUMAN
θ value	0.163984 (rank : 135)	NC score	0.073617 (rank : 221)
Query Neighborhood Hits	333	Target Neighborhood Hits	507	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

NCOA6_HUMAN
θ value	0.163984 (rank : 136)	NC score	0.050934 (rank : 272)
Query Neighborhood Hits	333	Target Neighborhood Hits	1202	Shared Neighborhood Hits	94
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PDLI4_HUMAN
θ value	0.163984 (rank : 137)	NC score	0.162661 (rank : 155)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

PDZD2_HUMAN
θ value	0.163984 (rank : 138)	NC score	0.260185 (rank : 104)
Query Neighborhood Hits	333	Target Neighborhood Hits	772	Shared Neighborhood Hits	167
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RECQ5_HUMAN
θ value	0.163984 (rank : 139)	NC score	0.028856 (rank : 321)
Query Neighborhood Hits	333	Target Neighborhood Hits	390	Shared Neighborhood Hits	40
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RHPN2_HUMAN
θ value	0.163984 (rank : 140)	NC score	0.093334 (rank : 209)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

AP3B1_MOUSE
θ value	0.21417 (rank : 141)	NC score	0.025180 (rank : 328)
Query Neighborhood Hits	333	Target Neighborhood Hits	302	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DLG5_HUMAN
θ value	0.21417 (rank : 142)	NC score	0.169473 (rank : 148)
Query Neighborhood Hits	333	Target Neighborhood Hits	1088	Shared Neighborhood Hits	138
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

MAST3_HUMAN
θ value	0.21417 (rank : 143)	NC score	0.031175 (rank : 313)
Query Neighborhood Hits	333	Target Neighborhood Hits	1128	Shared Neighborhood Hits	125
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

SDK1_HUMAN
θ value	0.21417 (rank : 144)	NC score	0.005491 (rank : 387)
Query Neighborhood Hits	333	Target Neighborhood Hits	511	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

GPSM2_HUMAN
θ value	0.279714 (rank : 145)	NC score	0.044351 (rank : 286)
Query Neighborhood Hits	333	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	P81274, Q8N0Z5	Gene names	GPSM2, LGN
Domain Architecture
Description	G-protein signaling modulator 2 (Mosaic protein LGN).

NOS1_HUMAN
θ value	0.279714 (rank : 146)	NC score	0.138973 (rank : 174)
Query Neighborhood Hits	333	Target Neighborhood Hits	218	Shared Neighborhood Hits	114
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PTN4_HUMAN
θ value	0.279714 (rank : 147)	NC score	0.080831 (rank : 216)
Query Neighborhood Hits	333	Target Neighborhood Hits	303	Shared Neighborhood Hits	105
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RHPN2_MOUSE
θ value	0.279714 (rank : 148)	NC score	0.113719 (rank : 198)
Query Neighborhood Hits	333	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

AFAD_HUMAN
θ value	0.365318 (rank : 149)	NC score	0.178781 (rank : 142)
Query Neighborhood Hits	333	Target Neighborhood Hits	689	Shared Neighborhood Hits	117
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CO4A5_HUMAN
θ value	0.365318 (rank : 150)	NC score	0.069586 (rank : 226)
Query Neighborhood Hits	333	Target Neighborhood Hits	383	Shared Neighborhood Hits	60
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

DAB2_HUMAN
θ value	0.365318 (rank : 151)	NC score	0.039366 (rank : 294)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

LNX1_MOUSE
θ value	0.365318 (rank : 152)	NC score	0.240493 (rank : 109)
Query Neighborhood Hits	333	Target Neighborhood Hits	377	Shared Neighborhood Hits	124
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

SF01_MOUSE
θ value	0.365318 (rank : 153)	NC score	0.063705 (rank : 233)
Query Neighborhood Hits	333	Target Neighborhood Hits	240	Shared Neighborhood Hits	23
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

ATRX_HUMAN
θ value	0.47712 (rank : 154)	NC score	0.019999 (rank : 341)
Query Neighborhood Hits	333	Target Neighborhood Hits	842	Shared Neighborhood Hits	30
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

HRBL_HUMAN
θ value	0.47712 (rank : 155)	NC score	0.025530 (rank : 327)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

K1849_HUMAN
θ value	0.47712 (rank : 156)	NC score	0.205749 (rank : 121)
Query Neighborhood Hits	333	Target Neighborhood Hits	220	Shared Neighborhood Hits	115
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

NACAM_MOUSE
θ value	0.47712 (rank : 157)	NC score	0.042404 (rank : 289)
Query Neighborhood Hits	333	Target Neighborhood Hits	1866	Shared Neighborhood Hits	106
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PTN3_HUMAN
θ value	0.47712 (rank : 158)	NC score	0.079204 (rank : 217)
Query Neighborhood Hits	333	Target Neighborhood Hits	258	Shared Neighborhood Hits	103
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

SHAN2_HUMAN
θ value	0.47712 (rank : 159)	NC score	0.177903 (rank : 144)
Query Neighborhood Hits	333	Target Neighborhood Hits	346	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

TLX1_MOUSE
θ value	0.47712 (rank : 160)	NC score	0.006365 (rank : 384)
Query Neighborhood Hits	333	Target Neighborhood Hits	347	Shared Neighborhood Hits	16
SwissProt Accessions	P43345	Gene names	Tlx1, Hox11, Tlx-1
Domain Architecture
Description	T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Homeobox TLX-1).

APXL_HUMAN
θ value	0.62314 (rank : 161)	NC score	0.178422 (rank : 143)
Query Neighborhood Hits	333	Target Neighborhood Hits	553	Shared Neighborhood Hits	112
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ARBK1_MOUSE
θ value	0.62314 (rank : 162)	NC score	0.004685 (rank : 388)
Query Neighborhood Hits	333	Target Neighborhood Hits	849	Shared Neighborhood Hits	22
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

CO1A1_MOUSE
θ value	0.62314 (rank : 163)	NC score	0.071513 (rank : 224)
Query Neighborhood Hits	333	Target Neighborhood Hits	457	Shared Neighborhood Hits	63
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO9A1_MOUSE
θ value	0.62314 (rank : 164)	NC score	0.055193 (rank : 258)
Query Neighborhood Hits	333	Target Neighborhood Hits	477	Shared Neighborhood Hits	68
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

PSCBP_MOUSE
θ value	0.62314 (rank : 165)	NC score	0.210808 (rank : 117)
Query Neighborhood Hits	333	Target Neighborhood Hits	118	Shared Neighborhood Hits	106
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

RIMS2_HUMAN
θ value	0.62314 (rank : 166)	NC score	0.091347 (rank : 210)
Query Neighborhood Hits	333	Target Neighborhood Hits	342	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.62314 (rank : 167)	NC score	0.090565 (rank : 211)
Query Neighborhood Hits	333	Target Neighborhood Hits	376	Shared Neighborhood Hits	85
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SF01_HUMAN
θ value	0.62314 (rank : 168)	NC score	0.061020 (rank : 244)
Query Neighborhood Hits	333	Target Neighborhood Hits	287	Shared Neighborhood Hits	29
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SHAN2_MOUSE
θ value	0.62314 (rank : 169)	NC score	0.156586 (rank : 160)
Query Neighborhood Hits	333	Target Neighborhood Hits	446	Shared Neighborhood Hits	119
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SPAG8_HUMAN
θ value	0.62314 (rank : 170)	NC score	0.057060 (rank : 252)
Query Neighborhood Hits	333	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

CO5A2_HUMAN
θ value	0.813845 (rank : 171)	NC score	0.062043 (rank : 238)
Query Neighborhood Hits	333	Target Neighborhood Hits	760	Shared Neighborhood Hits	79
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

FXYD5_HUMAN
θ value	0.813845 (rank : 172)	NC score	0.036823 (rank : 299)
Query Neighborhood Hits	333	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DB9, Q6UW44, Q9HC34, Q9P039	Gene names	FXYD5, DYSAD, IWU1
Domain Architecture
Description	FXYD domain-containing ion transport regulator 5 precursor (Dysadherin).

IRK9_HUMAN
θ value	0.813845 (rank : 173)	NC score	0.006839 (rank : 381)
Query Neighborhood Hits	333	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q92806, Q5JW75	Gene names	KCNJ9, GIRK3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

ITCH_MOUSE
θ value	0.813845 (rank : 174)	NC score	0.017182 (rank : 350)
Query Neighborhood Hits	333	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

PDLI4_MOUSE
θ value	0.813845 (rank : 175)	NC score	0.156936 (rank : 159)
Query Neighborhood Hits	333	Target Neighborhood Hits	233	Shared Neighborhood Hits	101
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

RIMS1_HUMAN
θ value	0.813845 (rank : 176)	NC score	0.108820 (rank : 204)
Query Neighborhood Hits	333	Target Neighborhood Hits	437	Shared Neighborhood Hits	104
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

CSPG3_MOUSE
θ value	1.06291 (rank : 177)	NC score	0.006584 (rank : 382)
Query Neighborhood Hits	333	Target Neighborhood Hits	657	Shared Neighborhood Hits	25
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

K0141_HUMAN
θ value	1.06291 (rank : 178)	NC score	0.024463 (rank : 331)
Query Neighborhood Hits	333	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q14154, Q969R4, Q96EU9	Gene names	KIAA0141
Domain Architecture
Description	Protein KIAA0141.

PDLI7_HUMAN
θ value	1.06291 (rank : 179)	NC score	0.115300 (rank : 195)
Query Neighborhood Hits	333	Target Neighborhood Hits	547	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SDCB1_HUMAN
θ value	1.06291 (rank : 180)	NC score	0.186129 (rank : 137)
Query Neighborhood Hits	333	Target Neighborhood Hits	150	Shared Neighborhood Hits	109
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	1.06291 (rank : 181)	NC score	0.190815 (rank : 132)
Query Neighborhood Hits	333	Target Neighborhood Hits	144	Shared Neighborhood Hits	109
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SHAN1_HUMAN
θ value	1.06291 (rank : 182)	NC score	0.111690 (rank : 201)
Query Neighborhood Hits	333	Target Neighborhood Hits	1041	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SON_HUMAN
θ value	1.06291 (rank : 183)	NC score	0.048672 (rank : 279)
Query Neighborhood Hits	333	Target Neighborhood Hits	1568	Shared Neighborhood Hits	115
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

APBA3_HUMAN
θ value	1.38821 (rank : 184)	NC score	0.185188 (rank : 138)
Query Neighborhood Hits	333	Target Neighborhood Hits	201	Shared Neighborhood Hits	103
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

CE016_HUMAN
θ value	1.38821 (rank : 185)	NC score	0.027006 (rank : 324)
Query Neighborhood Hits	333	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

CO1A1_HUMAN
θ value	1.38821 (rank : 186)	NC score	0.069335 (rank : 227)
Query Neighborhood Hits	333	Target Neighborhood Hits	475	Shared Neighborhood Hits	64
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A2_HUMAN
θ value	1.38821 (rank : 187)	NC score	0.063544 (rank : 234)
Query Neighborhood Hits	333	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

HTRA2_HUMAN
θ value	1.38821 (rank : 188)	NC score	0.030249 (rank : 314)
Query Neighborhood Hits	333	Target Neighborhood Hits	30	Shared Neighborhood Hits	17
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

LNX1_HUMAN
θ value	1.38821 (rank : 189)	NC score	0.232964 (rank : 114)
Query Neighborhood Hits	333	Target Neighborhood Hits	379	Shared Neighborhood Hits	121
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

NCOR1_MOUSE
θ value	1.38821 (rank : 190)	NC score	0.029001 (rank : 319)
Query Neighborhood Hits	333	Target Neighborhood Hits	521	Shared Neighborhood Hits	41
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

OGFR_HUMAN
θ value	1.38821 (rank : 191)	NC score	0.048998 (rank : 278)
Query Neighborhood Hits	333	Target Neighborhood Hits	1582	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SYNP2_HUMAN
θ value	1.38821 (rank : 192)	NC score	0.157827 (rank : 158)
Query Neighborhood Hits	333	Target Neighborhood Hits	323	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TX1B3_HUMAN
θ value	1.38821 (rank : 193)	NC score	0.270769 (rank : 95)
Query Neighborhood Hits	333	Target Neighborhood Hits	161	Shared Neighborhood Hits	121
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	1.38821 (rank : 194)	NC score	0.270257 (rank : 96)
Query Neighborhood Hits	333	Target Neighborhood Hits	158	Shared Neighborhood Hits	120
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

BAT2_HUMAN
θ value	1.81305 (rank : 195)	NC score	0.057650 (rank : 250)
Query Neighborhood Hits	333	Target Neighborhood Hits	931	Shared Neighborhood Hits	87
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_MOUSE
θ value	1.81305 (rank : 196)	NC score	0.040015 (rank : 292)
Query Neighborhood Hits	333	Target Neighborhood Hits	2057	Shared Neighborhood Hits	129
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO7A1_HUMAN
θ value	1.81305 (rank : 197)	NC score	0.047392 (rank : 283)
Query Neighborhood Hits	333	Target Neighborhood Hits	807	Shared Neighborhood Hits	77
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COHA1_MOUSE
θ value	1.81305 (rank : 198)	NC score	0.062434 (rank : 237)
Query Neighborhood Hits	333	Target Neighborhood Hits	414	Shared Neighborhood Hits	62
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COJA1_HUMAN
θ value	1.81305 (rank : 199)	NC score	0.059059 (rank : 246)
Query Neighborhood Hits	333	Target Neighborhood Hits	323	Shared Neighborhood Hits	54
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

DAB2_MOUSE
θ value	1.81305 (rank : 200)	NC score	0.029386 (rank : 317)
Query Neighborhood Hits	333	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

ERCC6_HUMAN
θ value	1.81305 (rank : 201)	NC score	0.010778 (rank : 369)
Query Neighborhood Hits	333	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

GPSM1_HUMAN
θ value	1.81305 (rank : 202)	NC score	0.037861 (rank : 296)
Query Neighborhood Hits	333	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YR5, Q86SR5, Q969T1, Q9UFS8	Gene names	GPSM1, AGS3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

IL3B2_MOUSE
θ value	1.81305 (rank : 203)	NC score	0.032927 (rank : 307)
Query Neighborhood Hits	333	Target Neighborhood Hits	372	Shared Neighborhood Hits	48
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

MAST4_HUMAN
θ value	1.81305 (rank : 204)	NC score	0.032343 (rank : 310)
Query Neighborhood Hits	333	Target Neighborhood Hits	1804	Shared Neighborhood Hits	167
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MTMR7_HUMAN
θ value	1.81305 (rank : 205)	NC score	0.019966 (rank : 342)
Query Neighborhood Hits	333	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

NMDE4_MOUSE
θ value	1.81305 (rank : 206)	NC score	0.012618 (rank : 363)
Query Neighborhood Hits	333	Target Neighborhood Hits	158	Shared Neighborhood Hits	18
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

PCLO_MOUSE
θ value	1.81305 (rank : 207)	NC score	0.102854 (rank : 208)
Query Neighborhood Hits	333	Target Neighborhood Hits	2275	Shared Neighborhood Hits	192
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SC24A_MOUSE
θ value	1.81305 (rank : 208)	NC score	0.032885 (rank : 308)
Query Neighborhood Hits	333	Target Neighborhood Hits	394	Shared Neighborhood Hits	40
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SMRC2_MOUSE
θ value	1.81305 (rank : 209)	NC score	0.037719 (rank : 297)
Query Neighborhood Hits	333	Target Neighborhood Hits	487	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SYP2L_MOUSE
θ value	1.81305 (rank : 210)	NC score	0.172167 (rank : 146)
Query Neighborhood Hits	333	Target Neighborhood Hits	289	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ATRX_MOUSE
θ value	2.36792 (rank : 211)	NC score	0.021270 (rank : 339)
Query Neighborhood Hits	333	Target Neighborhood Hits	682	Shared Neighborhood Hits	36
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CCNL1_HUMAN
θ value	2.36792 (rank : 212)	NC score	0.012139 (rank : 365)
Query Neighborhood Hits	333	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CD2L7_HUMAN
θ value	2.36792 (rank : 213)	NC score	0.000678 (rank : 396)
Query Neighborhood Hits	333	Target Neighborhood Hits	1275	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CJ006_HUMAN
θ value	2.36792 (rank : 214)	NC score	0.019576 (rank : 343)
Query Neighborhood Hits	333	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IX21, Q5W0L8, Q9NPE8	Gene names	C10orf6
Domain Architecture	No domain graphic available
Description	Protein C10orf6.

CO1A2_MOUSE
θ value	2.36792 (rank : 215)	NC score	0.062918 (rank : 235)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	58
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A2_MOUSE
θ value	2.36792 (rank : 216)	NC score	0.056431 (rank : 256)
Query Neighborhood Hits	333	Target Neighborhood Hits	492	Shared Neighborhood Hits	70
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO4A4_HUMAN
θ value	2.36792 (rank : 217)	NC score	0.061579 (rank : 242)
Query Neighborhood Hits	333	Target Neighborhood Hits	440	Shared Neighborhood Hits	69
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

GPSM2_MOUSE
θ value	2.36792 (rank : 218)	NC score	0.036946 (rank : 298)
Query Neighborhood Hits	333	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VDU0, Q8BLX3	Gene names	Gpsm2, Lgn, Pins
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 2 (Pins homolog).

IRS2_MOUSE
θ value	2.36792 (rank : 219)	NC score	0.032011 (rank : 312)
Query Neighborhood Hits	333	Target Neighborhood Hits	248	Shared Neighborhood Hits	32
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

K1849_MOUSE
θ value	2.36792 (rank : 220)	NC score	0.204297 (rank : 124)
Query Neighborhood Hits	333	Target Neighborhood Hits	335	Shared Neighborhood Hits	150
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

LBXCO_MOUSE
θ value	2.36792 (rank : 221)	NC score	0.022369 (rank : 334)
Query Neighborhood Hits	333	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

LNX2_HUMAN
θ value	2.36792 (rank : 222)	NC score	0.239333 (rank : 112)
Query Neighborhood Hits	333	Target Neighborhood Hits	389	Shared Neighborhood Hits	130
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

SFPQ_MOUSE
θ value	2.36792 (rank : 223)	NC score	0.040093 (rank : 291)
Query Neighborhood Hits	333	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SMRC2_HUMAN
θ value	2.36792 (rank : 224)	NC score	0.033609 (rank : 305)
Query Neighborhood Hits	333	Target Neighborhood Hits	499	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ZN213_HUMAN
θ value	2.36792 (rank : 225)	NC score	-0.006378 (rank : 404)
Query Neighborhood Hits	333	Target Neighborhood Hits	755	Shared Neighborhood Hits	5
SwissProt Accessions	O14771, Q96IS1	Gene names	ZNF213
Domain Architecture
Description	Zinc finger protein 213 (Putative transcription factor CR53).

ARBK1_HUMAN
θ value	3.0926 (rank : 226)	NC score	0.007005 (rank : 380)
Query Neighborhood Hits	333	Target Neighborhood Hits	859	Shared Neighborhood Hits	26
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

CO2A1_HUMAN
θ value	3.0926 (rank : 227)	NC score	0.061937 (rank : 240)
Query Neighborhood Hits	333	Target Neighborhood Hits	486	Shared Neighborhood Hits	68
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A1_HUMAN
θ value	3.0926 (rank : 228)	NC score	0.058963 (rank : 247)
Query Neighborhood Hits	333	Target Neighborhood Hits	425	Shared Neighborhood Hits	63
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A6_HUMAN
θ value	3.0926 (rank : 229)	NC score	0.058819 (rank : 248)
Query Neighborhood Hits	333	Target Neighborhood Hits	318	Shared Neighborhood Hits	53
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CO9A1_HUMAN
θ value	3.0926 (rank : 230)	NC score	0.053536 (rank : 266)
Query Neighborhood Hits	333	Target Neighborhood Hits	420	Shared Neighborhood Hits	62
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COAA1_HUMAN
θ value	3.0926 (rank : 231)	NC score	0.054287 (rank : 264)
Query Neighborhood Hits	333	Target Neighborhood Hits	316	Shared Neighborhood Hits	59
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

DTX1_MOUSE
θ value	3.0926 (rank : 232)	NC score	0.023875 (rank : 332)
Query Neighborhood Hits	333	Target Neighborhood Hits	99	Shared Neighborhood Hits	19
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

DVL3_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.163514 (rank : 152)
Query Neighborhood Hits	333	Target Neighborhood Hits	194	Shared Neighborhood Hits	94
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
θ value	3.0926 (rank : 234)	NC score	0.163212 (rank : 153)
Query Neighborhood Hits	333	Target Neighborhood Hits	198	Shared Neighborhood Hits	94
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

LIPB2_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.006462 (rank : 383)
Query Neighborhood Hits	333	Target Neighborhood Hits	599	Shared Neighborhood Hits	18
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

MAP1A_HUMAN
θ value	3.0926 (rank : 236)	NC score	0.021284 (rank : 338)
Query Neighborhood Hits	333	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MARCO_MOUSE
θ value	3.0926 (rank : 237)	NC score	0.041108 (rank : 290)
Query Neighborhood Hits	333	Target Neighborhood Hits	242	Shared Neighborhood Hits	40
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

MAST1_HUMAN
θ value	3.0926 (rank : 238)	NC score	0.028866 (rank : 320)
Query Neighborhood Hits	333	Target Neighborhood Hits	1146	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	3.0926 (rank : 239)	NC score	0.029722 (rank : 316)
Query Neighborhood Hits	333	Target Neighborhood Hits	1123	Shared Neighborhood Hits	133
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MINT_MOUSE
θ value	3.0926 (rank : 240)	NC score	0.025814 (rank : 326)
Query Neighborhood Hits	333	Target Neighborhood Hits	1514	Shared Neighborhood Hits	78
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PDZD7_HUMAN
θ value	3.0926 (rank : 241)	NC score	0.312237 (rank : 58)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	126
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

PRR12_HUMAN
θ value	3.0926 (rank : 242)	NC score	0.061769 (rank : 241)
Query Neighborhood Hits	333	Target Neighborhood Hits	460	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SDCB2_HUMAN
θ value	3.0926 (rank : 243)	NC score	0.158624 (rank : 157)
Query Neighborhood Hits	333	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_MOUSE
θ value	3.0926 (rank : 244)	NC score	0.160737 (rank : 156)
Query Neighborhood Hits	333	Target Neighborhood Hits	118	Shared Neighborhood Hits	87
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

ALO17_HUMAN
θ value	4.03905 (rank : 245)	NC score	0.021822 (rank : 336)
Query Neighborhood Hits	333	Target Neighborhood Hits	317	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

AP3B1_HUMAN
θ value	4.03905 (rank : 246)	NC score	0.018183 (rank : 347)
Query Neighborhood Hits	333	Target Neighborhood Hits	283	Shared Neighborhood Hits	16
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CO2A1_MOUSE
θ value	4.03905 (rank : 247)	NC score	0.061940 (rank : 239)
Query Neighborhood Hits	333	Target Neighborhood Hits	483	Shared Neighborhood Hits	63
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A2_HUMAN
θ value	4.03905 (rank : 248)	NC score	0.056465 (rank : 254)
Query Neighborhood Hits	333	Target Neighborhood Hits	454	Shared Neighborhood Hits	66
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

EP300_HUMAN
θ value	4.03905 (rank : 249)	NC score	0.035732 (rank : 303)
Query Neighborhood Hits	333	Target Neighborhood Hits	821	Shared Neighborhood Hits	81
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

KSR1_HUMAN
θ value	4.03905 (rank : 250)	NC score	-0.003862 (rank : 402)
Query Neighborhood Hits	333	Target Neighborhood Hits	867	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

LMNB1_HUMAN
θ value	4.03905 (rank : 251)	NC score	0.002747 (rank : 394)
Query Neighborhood Hits	333	Target Neighborhood Hits	714	Shared Neighborhood Hits	20
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

LMNB1_MOUSE
θ value	4.03905 (rank : 252)	NC score	0.002764 (rank : 393)
Query Neighborhood Hits	333	Target Neighborhood Hits	719	Shared Neighborhood Hits	18
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

MKL1_MOUSE
θ value	4.03905 (rank : 253)	NC score	0.025167 (rank : 329)
Query Neighborhood Hits	333	Target Neighborhood Hits	667	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MY18A_HUMAN
θ value	4.03905 (rank : 254)	NC score	0.029797 (rank : 315)
Query Neighborhood Hits	333	Target Neighborhood Hits	1929	Shared Neighborhood Hits	128
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	4.03905 (rank : 255)	NC score	0.032316 (rank : 311)
Query Neighborhood Hits	333	Target Neighborhood Hits	1989	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PARC_HUMAN
θ value	4.03905 (rank : 256)	NC score	0.007697 (rank : 378)
Query Neighborhood Hits	333	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PSCBP_HUMAN
θ value	4.03905 (rank : 257)	NC score	0.186737 (rank : 135)
Query Neighborhood Hits	333	Target Neighborhood Hits	123	Shared Neighborhood Hits	102
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

SPRL1_MOUSE
θ value	4.03905 (rank : 258)	NC score	0.011683 (rank : 367)
Query Neighborhood Hits	333	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SYJ2B_HUMAN
θ value	4.03905 (rank : 259)	NC score	0.296020 (rank : 72)
Query Neighborhood Hits	333	Target Neighborhood Hits	162	Shared Neighborhood Hits	119
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

TLN1_HUMAN
θ value	4.03905 (rank : 260)	NC score	0.016346 (rank : 352)
Query Neighborhood Hits	333	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TM108_MOUSE
θ value	4.03905 (rank : 261)	NC score	0.033602 (rank : 306)
Query Neighborhood Hits	333	Target Neighborhood Hits	336	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

UBP34_HUMAN
θ value	4.03905 (rank : 262)	NC score	0.010114 (rank : 371)
Query Neighborhood Hits	333	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	4.03905 (rank : 263)	NC score	0.010304 (rank : 370)
Query Neighborhood Hits	333	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

WNK2_HUMAN
θ value	4.03905 (rank : 264)	NC score	0.007953 (rank : 377)
Query Neighborhood Hits	333	Target Neighborhood Hits	1407	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZO1_HUMAN
θ value	4.03905 (rank : 265)	NC score	0.201804 (rank : 126)
Query Neighborhood Hits	333	Target Neighborhood Hits	474	Shared Neighborhood Hits	134
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	4.03905 (rank : 266)	NC score	0.204930 (rank : 123)
Query Neighborhood Hits	333	Target Neighborhood Hits	453	Shared Neighborhood Hits	145
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
θ value	4.03905 (rank : 267)	NC score	0.205722 (rank : 122)
Query Neighborhood Hits	333	Target Neighborhood Hits	289	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

BTBDA_MOUSE
θ value	5.27518 (rank : 268)	NC score	0.017489 (rank : 349)
Query Neighborhood Hits	333	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X66	Gene names	Btbd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

CCD96_HUMAN
θ value	5.27518 (rank : 269)	NC score	0.011159 (rank : 368)
Query Neighborhood Hits	333	Target Neighborhood Hits	595	Shared Neighborhood Hits	26
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CO9A3_HUMAN
θ value	5.27518 (rank : 270)	NC score	0.055026 (rank : 260)
Query Neighborhood Hits	333	Target Neighborhood Hits	361	Shared Neighborhood Hits	58
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COCA1_HUMAN
θ value	5.27518 (rank : 271)	NC score	0.032409 (rank : 309)
Query Neighborhood Hits	333	Target Neighborhood Hits	458	Shared Neighborhood Hits	50
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	5.27518 (rank : 272)	NC score	0.039352 (rank : 295)
Query Neighborhood Hits	333	Target Neighborhood Hits	427	Shared Neighborhood Hits	56
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	5.27518 (rank : 273)	NC score	0.036761 (rank : 300)
Query Neighborhood Hits	333	Target Neighborhood Hits	402	Shared Neighborhood Hits	53
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CTHR1_HUMAN
θ value	5.27518 (rank : 274)	NC score	0.039460 (rank : 293)
Query Neighborhood Hits	333	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

DHX37_HUMAN
θ value	5.27518 (rank : 275)	NC score	0.008700 (rank : 376)
Query Neighborhood Hits	333	Target Neighborhood Hits	133	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

DTX1_HUMAN
θ value	5.27518 (rank : 276)	NC score	0.016513 (rank : 351)
Query Neighborhood Hits	333	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

HTRA2_MOUSE
θ value	5.27518 (rank : 277)	NC score	0.024669 (rank : 330)
Query Neighborhood Hits	333	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

IRS2_HUMAN
θ value	5.27518 (rank : 278)	NC score	0.034582 (rank : 304)
Query Neighborhood Hits	333	Target Neighborhood Hits	262	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MAML2_HUMAN
θ value	5.27518 (rank : 279)	NC score	0.013892 (rank : 358)
Query Neighborhood Hits	333	Target Neighborhood Hits	360	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MAST2_HUMAN
θ value	5.27518 (rank : 280)	NC score	0.029312 (rank : 318)
Query Neighborhood Hits	333	Target Neighborhood Hits	1189	Shared Neighborhood Hits	124
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NCOR1_HUMAN
θ value	5.27518 (rank : 281)	NC score	0.021563 (rank : 337)
Query Neighborhood Hits	333	Target Neighborhood Hits	577	Shared Neighborhood Hits	33
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

PAX5_MOUSE
θ value	5.27518 (rank : 282)	NC score	0.004549 (rank : 389)
Query Neighborhood Hits	333	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

SLAP1_MOUSE
θ value	5.27518 (rank : 283)	NC score	0.003278 (rank : 391)
Query Neighborhood Hits	333	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

ZN750_MOUSE
θ value	5.27518 (rank : 284)	NC score	0.017802 (rank : 348)
Query Neighborhood Hits	333	Target Neighborhood Hits	346	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AFF2_HUMAN
θ value	6.88961 (rank : 285)	NC score	0.013392 (rank : 359)
Query Neighborhood Hits	333	Target Neighborhood Hits	218	Shared Neighborhood Hits	23
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

AKAP1_MOUSE
θ value	6.88961 (rank : 286)	NC score	0.013037 (rank : 360)
Query Neighborhood Hits	333	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

APC_HUMAN
θ value	6.88961 (rank : 287)	NC score	0.020518 (rank : 340)
Query Neighborhood Hits	333	Target Neighborhood Hits	603	Shared Neighborhood Hits	36
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BAT2_MOUSE
θ value	6.88961 (rank : 288)	NC score	0.047883 (rank : 282)
Query Neighborhood Hits	333	Target Neighborhood Hits	947	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_HUMAN
θ value	6.88961 (rank : 289)	NC score	0.046303 (rank : 284)
Query Neighborhood Hits	333	Target Neighborhood Hits	1008	Shared Neighborhood Hits	99
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BTBDA_HUMAN
θ value	6.88961 (rank : 290)	NC score	0.016298 (rank : 353)
Query Neighborhood Hits	333	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSF8, Q86WG1	Gene names	BTBD10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

CIR_MOUSE
θ value	6.88961 (rank : 291)	NC score	0.009440 (rank : 374)
Query Neighborhood Hits	333	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CO4A3_HUMAN
θ value	6.88961 (rank : 292)	NC score	0.057200 (rank : 251)
Query Neighborhood Hits	333	Target Neighborhood Hits	421	Shared Neighborhood Hits	61
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

COHA1_HUMAN
θ value	6.88961 (rank : 293)	NC score	0.064490 (rank : 230)
Query Neighborhood Hits	333	Target Neighborhood Hits	400	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CS007_HUMAN
θ value	6.88961 (rank : 294)	NC score	0.036211 (rank : 302)
Query Neighborhood Hits	333	Target Neighborhood Hits	401	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CUTL2_HUMAN
θ value	6.88961 (rank : 295)	NC score	0.009547 (rank : 372)
Query Neighborhood Hits	333	Target Neighborhood Hits	906	Shared Neighborhood Hits	37
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DJC16_MOUSE
θ value	6.88961 (rank : 296)	NC score	0.003039 (rank : 392)
Query Neighborhood Hits	333	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TN4, Q811G1, Q8BHI2	Gene names	Dnajc16, Kiaa0962
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 16 precursor.

DOK2_MOUSE
θ value	6.88961 (rank : 297)	NC score	0.012925 (rank : 361)
Query Neighborhood Hits	333	Target Neighborhood Hits	244	Shared Neighborhood Hits	28
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

HAP1_MOUSE
θ value	6.88961 (rank : 298)	NC score	0.009529 (rank : 373)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	13
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

ING1_HUMAN
θ value	6.88961 (rank : 299)	NC score	0.006243 (rank : 385)
Query Neighborhood Hits	333	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

JADE2_MOUSE
θ value	6.88961 (rank : 300)	NC score	0.015497 (rank : 354)
Query Neighborhood Hits	333	Target Neighborhood Hits	560	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LNX2_MOUSE
θ value	6.88961 (rank : 301)	NC score	0.239440 (rank : 111)
Query Neighborhood Hits	333	Target Neighborhood Hits	407	Shared Neighborhood Hits	129
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MAST2_MOUSE
θ value	6.88961 (rank : 302)	NC score	0.027802 (rank : 322)
Query Neighborhood Hits	333	Target Neighborhood Hits	1110	Shared Neighborhood Hits	119
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MY18B_HUMAN
θ value	6.88961 (rank : 303)	NC score	0.014157 (rank : 356)
Query Neighborhood Hits	333	Target Neighborhood Hits	1299	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYRIP_MOUSE
θ value	6.88961 (rank : 304)	NC score	0.012613 (rank : 364)
Query Neighborhood Hits	333	Target Neighborhood Hits	207	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

RRP44_HUMAN
θ value	6.88961 (rank : 305)	NC score	0.012730 (rank : 362)
Query Neighborhood Hits	333	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

TAF4_HUMAN
θ value	6.88961 (rank : 306)	NC score	0.043829 (rank : 287)
Query Neighborhood Hits	333	Target Neighborhood Hits	687	Shared Neighborhood Hits	53
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

THOC2_HUMAN
θ value	6.88961 (rank : 307)	NC score	0.011828 (rank : 366)
Query Neighborhood Hits	333	Target Neighborhood Hits	337	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TLN1_MOUSE
θ value	6.88961 (rank : 308)	NC score	0.015346 (rank : 355)
Query Neighborhood Hits	333	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TTC16_HUMAN
θ value	6.88961 (rank : 309)	NC score	0.008786 (rank : 375)
Query Neighborhood Hits	333	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ZC3H6_MOUSE
θ value	6.88961 (rank : 310)	NC score	0.014127 (rank : 357)
Query Neighborhood Hits	333	Target Neighborhood Hits	239	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZIMP7_MOUSE
θ value	6.88961 (rank : 311)	NC score	0.026107 (rank : 325)
Query Neighborhood Hits	333	Target Neighborhood Hits	566	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ADA1D_HUMAN
θ value	8.99809 (rank : 312)	NC score	-0.008340 (rank : 405)
Query Neighborhood Hits	333	Target Neighborhood Hits	937	Shared Neighborhood Hits	12
SwissProt Accessions	P25100, Q9NPY0	Gene names	ADRA1D, ADRA1A
Domain Architecture
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D- adrenoreceptor) (Alpha-1A adrenergic receptor) (Alpha adrenergic receptor 1a).

ATX2_HUMAN
θ value	8.99809 (rank : 313)	NC score	0.023004 (rank : 333)
Query Neighborhood Hits	333	Target Neighborhood Hits	375	Shared Neighborhood Hits	33
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

COBA2_HUMAN
θ value	8.99809 (rank : 314)	NC score	0.051752 (rank : 268)
Query Neighborhood Hits	333	Target Neighborhood Hits	408	Shared Neighborhood Hits	58
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

DJBP_HUMAN
θ value	8.99809 (rank : 315)	NC score	0.005571 (rank : 386)
Query Neighborhood Hits	333	Target Neighborhood Hits	156	Shared Neighborhood Hits	3
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

DVL1L_HUMAN
θ value	8.99809 (rank : 316)	NC score	0.144075 (rank : 172)
Query Neighborhood Hits	333	Target Neighborhood Hits	146	Shared Neighborhood Hits	90
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	8.99809 (rank : 317)	NC score	0.150708 (rank : 161)
Query Neighborhood Hits	333	Target Neighborhood Hits	158	Shared Neighborhood Hits	96
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL1_MOUSE
θ value	8.99809 (rank : 318)	NC score	0.147196 (rank : 168)
Query Neighborhood Hits	333	Target Neighborhood Hits	146	Shared Neighborhood Hits	90
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

ELN_HUMAN
θ value	8.99809 (rank : 319)	NC score	0.051817 (rank : 267)
Query Neighborhood Hits	333	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

FOXK1_MOUSE
θ value	8.99809 (rank : 320)	NC score	0.000549 (rank : 397)
Query Neighborhood Hits	333	Target Neighborhood Hits	215	Shared Neighborhood Hits	10
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

GP152_MOUSE
θ value	8.99809 (rank : 321)	NC score	0.000327 (rank : 398)
Query Neighborhood Hits	333	Target Neighborhood Hits	607	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

HRX_HUMAN
θ value	8.99809 (rank : 322)	NC score	0.018416 (rank : 346)
Query Neighborhood Hits	333	Target Neighborhood Hits	825	Shared Neighborhood Hits	53
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HXD9_MOUSE
θ value	8.99809 (rank : 323)	NC score	-0.001400 (rank : 401)
Query Neighborhood Hits	333	Target Neighborhood Hits	359	Shared Neighborhood Hits	9
SwissProt Accessions	P28357, Q3UYS2	Gene names	Hoxd9, Hox-4.4, Hoxd-9
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4.4) (Hox-5.2).

KI67_HUMAN
θ value	8.99809 (rank : 324)	NC score	0.018623 (rank : 345)
Query Neighborhood Hits	333	Target Neighborhood Hits	581	Shared Neighborhood Hits	39
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MLL3_HUMAN
θ value	8.99809 (rank : 325)	NC score	0.019263 (rank : 344)
Query Neighborhood Hits	333	Target Neighborhood Hits	1644	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NCOA6_MOUSE
θ value	8.99809 (rank : 326)	NC score	0.045725 (rank : 285)
Query Neighborhood Hits	333	Target Neighborhood Hits	1076	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

OBSCN_HUMAN
θ value	8.99809 (rank : 327)	NC score	-0.000921 (rank : 400)
Query Neighborhood Hits	333	Target Neighborhood Hits	1931	Shared Neighborhood Hits	73
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OTOF_MOUSE
θ value	8.99809 (rank : 328)	NC score	0.004488 (rank : 390)
Query Neighborhood Hits	333	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PDLI7_MOUSE
θ value	8.99809 (rank : 329)	NC score	0.106362 (rank : 207)
Query Neighborhood Hits	333	Target Neighborhood Hits	279	Shared Neighborhood Hits	91
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PZRN4_HUMAN
θ value	8.99809 (rank : 330)	NC score	0.185086 (rank : 139)
Query Neighborhood Hits	333	Target Neighborhood Hits	438	Shared Neighborhood Hits	106
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

SCN5A_HUMAN
θ value	8.99809 (rank : 331)	NC score	0.000963 (rank : 395)
Query Neighborhood Hits	333	Target Neighborhood Hits	145	Shared Neighborhood Hits	9
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

TRAIP_MOUSE
θ value	8.99809 (rank : 332)	NC score	0.000281 (rank : 399)
Query Neighborhood Hits	333	Target Neighborhood Hits	745	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

ZN409_HUMAN
θ value	8.99809 (rank : 333)	NC score	0.007546 (rank : 379)
Query Neighborhood Hits	333	Target Neighborhood Hits	842	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

APBA3_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.163155 (rank : 154)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	98
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

CN155_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.058075 (rank : 249)
Query Neighborhood Hits	333	Target Neighborhood Hits	385	Shared Neighborhood Hits	39
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO5A1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.055006 (rank : 261)
Query Neighborhood Hits	333	Target Neighborhood Hits	434	Shared Neighborhood Hits	61
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A1_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.055120 (rank : 259)
Query Neighborhood Hits	333	Target Neighborhood Hits	419	Shared Neighborhood Hits	60
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CO5A3_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.050782 (rank : 275)
Query Neighborhood Hits	333	Target Neighborhood Hits	433	Shared Neighborhood Hits	61
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

CO9A2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.050841 (rank : 274)
Query Neighborhood Hits	333	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO9A2_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.054507 (rank : 263)
Query Neighborhood Hits	333	Target Neighborhood Hits	279	Shared Neighborhood Hits	56
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COBA1_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.051503 (rank : 270)
Query Neighborhood Hits	333	Target Neighborhood Hits	491	Shared Neighborhood Hits	67
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.050570 (rank : 276)
Query Neighborhood Hits	333	Target Neighborhood Hits	487	Shared Neighborhood Hits	66
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COGA1_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.055385 (rank : 257)
Query Neighborhood Hits	333	Target Neighborhood Hits	345	Shared Neighborhood Hits	55
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

COIA1_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.051654 (rank : 269)
Query Neighborhood Hits	333	Target Neighborhood Hits	447	Shared Neighborhood Hits	63
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CONA1_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.050843 (rank : 273)
Query Neighborhood Hits	333	Target Neighborhood Hits	281	Shared Neighborhood Hits	51
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

DVL2_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.144681 (rank : 170)
Query Neighborhood Hits	333	Target Neighborhood Hits	223	Shared Neighborhood Hits	102
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.145409 (rank : 169)
Query Neighborhood Hits	333	Target Neighborhood Hits	233	Shared Neighborhood Hits	110
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

EM55_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.125909 (rank : 182)
Query Neighborhood Hits	333	Target Neighborhood Hits	228	Shared Neighborhood Hits	83
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.122624 (rank : 189)
Query Neighborhood Hits	333	Target Neighborhood Hits	221	Shared Neighborhood Hits	82
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

EMID2_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.051212 (rank : 271)
Query Neighborhood Hits	333	Target Neighborhood Hits	226	Shared Neighborhood Hits	49
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

GIPC1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.067860 (rank : 228)
Query Neighborhood Hits	333	Target Neighborhood Hits	91	Shared Neighborhood Hits	61
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

GIPC1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.072790 (rank : 222)
Query Neighborhood Hits	333	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

GIPC2_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.062462 (rank : 236)
Query Neighborhood Hits	333	Target Neighborhood Hits	93	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

IL16_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.234257 (rank : 113)
Query Neighborhood Hits	333	Target Neighborhood Hits	207	Shared Neighborhood Hits	110
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IL16_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.221182 (rank : 116)
Query Neighborhood Hits	333	Target Neighborhood Hits	189	Shared Neighborhood Hits	106
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

KGUA_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.084904 (rank : 213)
Query Neighborhood Hits	333	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.085762 (rank : 212)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LAP2_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.075092 (rank : 219)
Query Neighborhood Hits	333	Target Neighborhood Hits	499	Shared Neighborhood Hits	85
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.071048 (rank : 225)
Query Neighborhood Hits	333	Target Neighborhood Hits	482	Shared Neighborhood Hits	87
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LDB3_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.119622 (rank : 193)
Query Neighborhood Hits	333	Target Neighborhood Hits	497	Shared Neighborhood Hits	119
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.116009 (rank : 194)
Query Neighborhood Hits	333	Target Neighborhood Hits	510	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LRRC7_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.083048 (rank : 214)
Query Neighborhood Hits	333	Target Neighborhood Hits	423	Shared Neighborhood Hits	101
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.082054 (rank : 215)
Query Neighborhood Hits	333	Target Neighborhood Hits	416	Shared Neighborhood Hits	98
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MPP2_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.107722 (rank : 205)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	67
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.109831 (rank : 203)
Query Neighborhood Hits	333	Target Neighborhood Hits	189	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP3_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.147210 (rank : 167)
Query Neighborhood Hits	333	Target Neighborhood Hits	171	Shared Neighborhood Hits	90
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.147395 (rank : 166)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	90
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.167922 (rank : 150)
Query Neighborhood Hits	333	Target Neighborhood Hits	205	Shared Neighborhood Hits	104
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MPP4_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.148127 (rank : 165)
Query Neighborhood Hits	333	Target Neighborhood Hits	188	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP5_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.149892 (rank : 162)
Query Neighborhood Hits	333	Target Neighborhood Hits	231	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.149398 (rank : 163)
Query Neighborhood Hits	333	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP6_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.106719 (rank : 206)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MPP6_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.110247 (rank : 202)
Query Neighborhood Hits	333	Target Neighborhood Hits	187	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

NEB1_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.125758 (rank : 185)
Query Neighborhood Hits	333	Target Neighborhood Hits	829	Shared Neighborhood Hits	100
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.120242 (rank : 191)
Query Neighborhood Hits	333	Target Neighborhood Hits	883	Shared Neighborhood Hits	94
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.120267 (rank : 190)
Query Neighborhood Hits	333	Target Neighborhood Hits	889	Shared Neighborhood Hits	98
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PAR3L_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.255802 (rank : 105)
Query Neighborhood Hits	333	Target Neighborhood Hits	297	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PAR6A_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.113832 (rank : 197)
Query Neighborhood Hits	333	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

PAR6A_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.114497 (rank : 196)
Query Neighborhood Hits	333	Target Neighborhood Hits	115	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6B_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.125237 (rank : 186)
Query Neighborhood Hits	333	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6B_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.125766 (rank : 184)
Query Neighborhood Hits	333	Target Neighborhood Hits	128	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PAR6G_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.131248 (rank : 177)
Query Neighborhood Hits	333	Target Neighborhood Hits	159	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PAR6G_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.125785 (rank : 183)
Query Neighborhood Hits	333	Target Neighborhood Hits	121	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PDLI1_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.139974 (rank : 173)
Query Neighborhood Hits	333	Target Neighborhood Hits	242	Shared Neighborhood Hits	91
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI1_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.144285 (rank : 171)
Query Neighborhood Hits	333	Target Neighborhood Hits	213	Shared Neighborhood Hits	91
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

PDLI2_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.193590 (rank : 131)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	111
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

PDZD6_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.059978 (rank : 245)
Query Neighborhood Hits	333	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PDZD8_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.064261 (rank : 232)
Query Neighborhood Hits	333	Target Neighborhood Hits	185	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PDZK4_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.113359 (rank : 199)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	85
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.113346 (rank : 200)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PICK1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.138861 (rank : 175)
Query Neighborhood Hits	333	Target Neighborhood Hits	132	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.138440 (rank : 176)
Query Neighborhood Hits	333	Target Neighborhood Hits	131	Shared Neighborhood Hits	87
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PRB3_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.056458 (rank : 255)
Query Neighborhood Hits	333	Target Neighborhood Hits	318	Shared Neighborhood Hits	46
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.056994 (rank : 253)
Query Neighborhood Hits	333	Target Neighborhood Hits	330	Shared Neighborhood Hits	47
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.054235 (rank : 265)
Query Neighborhood Hits	333	Target Neighborhood Hits	385	Shared Neighborhood Hits	51
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.061076 (rank : 243)
Query Neighborhood Hits	333	Target Neighborhood Hits	347	Shared Neighborhood Hits	43
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PZRN3_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.183191 (rank : 141)
Query Neighborhood Hits	333	Target Neighborhood Hits	461	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.184269 (rank : 140)
Query Neighborhood Hits	333	Target Neighborhood Hits	447	Shared Neighborhood Hits	111
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RPGF2_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.130258 (rank : 178)
Query Neighborhood Hits	333	Target Neighborhood Hits	242	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

RPGF6_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.149280 (rank : 164)
Query Neighborhood Hits	333	Target Neighborhood Hits	266	Shared Neighborhood Hits	122
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SNX14_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.050065 (rank : 277)
Query Neighborhood Hits	333	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

SNX25_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.128522 (rank : 179)
Query Neighborhood Hits	333	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

STXB4_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.122797 (rank : 188)
Query Neighborhood Hits	333	Target Neighborhood Hits	616	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

STXB4_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.120013 (rank : 192)
Query Neighborhood Hits	333	Target Neighborhood Hits	629	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

ZO2_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.199945 (rank : 127)
Query Neighborhood Hits	333	Target Neighborhood Hits	296	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

Hits sorted by NC score

RGS12_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	333	Target Neighborhood Hits	333	Shared Neighborhood Hits	333
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RGS14_MOUSE
NC score	0.862180 (rank : 2)	θ value	3.00772e-96 (rank : 2)
Query Neighborhood Hits	333	Target Neighborhood Hits	55	Shared Neighborhood Hits	44
SwissProt Accessions	P97492, Q9DCD1	Gene names	Rgs14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein).

RGS14_HUMAN
NC score	0.859969 (rank : 3)	θ value	6.27148e-94 (rank : 3)
Query Neighborhood Hits	333	Target Neighborhood Hits	77	Shared Neighborhood Hits	47
SwissProt Accessions	O43566, O43565, Q8TD62	Gene names	RGS14
Domain Architecture
Description	Regulator of G-protein signaling 14 (RGS14).

RGS10_MOUSE
NC score	0.825746 (rank : 4)	θ value	2.12192e-33 (rank : 5)
Query Neighborhood Hits	333	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CQE5, Q9D3L2	Gene names	Rgs10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS10_HUMAN
NC score	0.825553 (rank : 5)	θ value	2.50655e-34 (rank : 4)
Query Neighborhood Hits	333	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	O43665	Gene names	RGS10
Domain Architecture
Description	Regulator of G-protein signaling 10 (RGS10).

RGS19_MOUSE
NC score	0.774230 (rank : 6)	θ value	1.02238e-19 (rank : 9)
Query Neighborhood Hits	333	Target Neighborhood Hits	46	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CX84, Q99L50	Gene names	Rgs19
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19).

RGS17_HUMAN
NC score	0.773650 (rank : 7)	θ value	7.82807e-20 (rank : 8)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UGC6, Q5TF49, Q8TD61, Q9UJS8	Gene names	RGS17
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17).

RGS17_MOUSE
NC score	0.772980 (rank : 8)	θ value	1.74391e-19 (rank : 14)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZB0, Q543T9	Gene names	Rgs17, Rgsz2
Domain Architecture
Description	Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2).

RGS4_MOUSE
NC score	0.772362 (rank : 9)	θ value	1.33526e-19 (rank : 13)
Query Neighborhood Hits	333	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	O08899, Q99L30	Gene names	Rgs4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4).

RGS4_HUMAN
NC score	0.771574 (rank : 10)	θ value	1.02238e-19 (rank : 10)
Query Neighborhood Hits	333	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	P49798	Gene names	RGS4
Domain Architecture
Description	Regulator of G-protein signaling 4 (RGS4) (RGP4).

RGS1_HUMAN
NC score	0.771512 (rank : 11)	θ value	2.5182e-18 (rank : 17)
Query Neighborhood Hits	333	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	Q08116, Q07918, Q9H1W2	Gene names	RGS1, 1R20, BL34
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1) (Early response protein 1R20) (B-cell activation protein BL34).

RGS1_MOUSE
NC score	0.771135 (rank : 12)	θ value	3.63628e-17 (rank : 21)
Query Neighborhood Hits	333	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

RGS20_MOUSE
NC score	0.771052 (rank : 13)	θ value	2.7842e-17 (rank : 20)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZB1, Q3TY63, Q9CUV8, Q9QZB2	Gene names	Rgs20, Rgsz1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1).

RGS19_HUMAN
NC score	0.770604 (rank : 14)	θ value	8.65492e-19 (rank : 16)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	P49795, Q53XN0, Q8TD60	Gene names	RGS19, GAIP, GNAI3IP
Domain Architecture
Description	Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP protein).

RGS5_MOUSE
NC score	0.769386 (rank : 15)	θ value	2.60593e-15 (rank : 32)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	45
SwissProt Accessions	O08850, Q543B1, Q9D0Z2	Gene names	Rgs5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS20_HUMAN
NC score	0.767388 (rank : 16)	θ value	8.10077e-17 (rank : 25)
Query Neighborhood Hits	333	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	O76081, Q96BG9	Gene names	RGS20, RGSZ1, ZGAP1
Domain Architecture
Description	Regulator of G-protein signaling 20 (RGS20) (Regulator of Gz-selective protein signaling 1) (Gz-selective GTPase-activating protein) (G(z)GAP).

RGS8_HUMAN
NC score	0.764217 (rank : 17)	θ value	1.80466e-16 (rank : 27)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P57771, Q3SYD2	Gene names	RGS8
Domain Architecture
Description	Regulator of G-protein signaling 8 (RGS8).

RGS8_MOUSE
NC score	0.763735 (rank : 18)	θ value	2.35696e-16 (rank : 29)
Query Neighborhood Hits	333	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BXT1	Gene names	Rgs8
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 8 (RGS8).

RGS16_HUMAN
NC score	0.762922 (rank : 19)	θ value	7.32683e-18 (rank : 19)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	O15492, Q99701	Gene names	RGS16, RGSR
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS18_HUMAN
NC score	0.762048 (rank : 20)	θ value	2.35696e-16 (rank : 28)
Query Neighborhood Hits	333	Target Neighborhood Hits	44	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS28	Gene names	RGS18, RGS13
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS16_MOUSE
NC score	0.761297 (rank : 21)	θ value	6.20254e-17 (rank : 24)
Query Neighborhood Hits	333	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	P97428, O09091, P97420, Q80V16	Gene names	Rgs16, Rgsr
Domain Architecture
Description	Regulator of G-protein signaling 16 (RGS16) (Retinally abundant regulator of G-protein signaling) (RGS-R) (A28-RGS14P).

RGS5_HUMAN
NC score	0.761257 (rank : 22)	θ value	4.91457e-14 (rank : 34)
Query Neighborhood Hits	333	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	O15539	Gene names	RGS5
Domain Architecture
Description	Regulator of G-protein signaling 5 (RGS5).

RGS18_MOUSE
NC score	0.760951 (rank : 23)	θ value	1.80466e-16 (rank : 26)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	Q99PG4	Gene names	Rgs18
Domain Architecture
Description	Regulator of G-protein signaling 18 (RGS18).

RGS13_HUMAN
NC score	0.756063 (rank : 24)	θ value	7.09661e-13 (rank : 36)
Query Neighborhood Hits	333	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	O14921, Q6PGR2, Q8TD63, Q9BX45	Gene names	RGS13
Domain Architecture
Description	Regulator of G-protein signaling 13 (RGS13).

RGS13_MOUSE
NC score	0.755173 (rank : 25)	θ value	2.43908e-13 (rank : 35)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K443	Gene names	Rgs13
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 13 (RGS13).

RGS2_HUMAN
NC score	0.752840 (rank : 26)	θ value	4.44505e-15 (rank : 33)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	43
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

RGS2_MOUSE
NC score	0.752295 (rank : 27)	θ value	1.99529e-15 (rank : 31)
Query Neighborhood Hits	333	Target Neighborhood Hits	52	Shared Neighborhood Hits	43
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RGS11_HUMAN
NC score	0.737060 (rank : 28)	θ value	3.51386e-20 (rank : 7)
Query Neighborhood Hits	333	Target Neighborhood Hits	68	Shared Neighborhood Hits	48
SwissProt Accessions	O94810, O75883	Gene names	RGS11
Domain Architecture
Description	Regulator of G-protein signaling 11 (RGS11).

RGS9_MOUSE
NC score	0.723600 (rank : 29)	θ value	2.69047e-20 (rank : 6)
Query Neighborhood Hits	333	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_HUMAN
NC score	0.722612 (rank : 30)	θ value	1.02238e-19 (rank : 12)
Query Neighborhood Hits	333	Target Neighborhood Hits	64	Shared Neighborhood Hits	45
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS7_MOUSE
NC score	0.717752 (rank : 31)	θ value	1.02238e-19 (rank : 11)
Query Neighborhood Hits	333	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS7_HUMAN
NC score	0.717733 (rank : 32)	θ value	5.07402e-19 (rank : 15)
Query Neighborhood Hits	333	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RGS6_MOUSE
NC score	0.713495 (rank : 33)	θ value	4.29542e-18 (rank : 18)
Query Neighborhood Hits	333	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z2H2, Q8BGI8	Gene names	Rgs6
Domain Architecture	No domain graphic available
Description	Regulator of G-protein signaling 6 (RGS6).

RGS6_HUMAN
NC score	0.693910 (rank : 34)	θ value	6.85773e-16 (rank : 30)
Query Neighborhood Hits	333	Target Neighborhood Hits	80	Shared Neighborhood Hits	43
SwissProt Accessions	P49758, O75576, O75577, Q8TE13, Q8TE14, Q8TE15, Q8TE16, Q8TE17, Q8TE18, Q8TE19, Q8TE20, Q8TE21, Q8TE22, Q9Y245, Q9Y647	Gene names	RGS6
Domain Architecture
Description	Regulator of G-protein signaling 6 (RGS6) (S914).

RGS3_HUMAN
NC score	0.596909 (rank : 35)	θ value	4.74913e-17 (rank : 22)
Query Neighborhood Hits	333	Target Neighborhood Hits	1375	Shared Neighborhood Hits	183
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

AXN1_MOUSE
NC score	0.543099 (rank : 36)	θ value	1.99992e-07 (rank : 38)
Query Neighborhood Hits	333	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	O35625	Gene names	Axin1, Axin, Fu
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (Fused protein).

RGS3_MOUSE
NC score	0.542439 (rank : 37)	θ value	4.74913e-17 (rank : 23)
Query Neighborhood Hits	333	Target Neighborhood Hits	1621	Shared Neighborhood Hits	192
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AXN1_HUMAN
NC score	0.526789 (rank : 38)	θ value	6.43352e-06 (rank : 44)
Query Neighborhood Hits	333	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

AXN2_HUMAN
NC score	0.513123 (rank : 39)	θ value	1.43324e-05 (rank : 45)
Query Neighborhood Hits	333	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y2T1, Q9H3M6, Q9UH84	Gene names	AXIN2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

AXN2_MOUSE
NC score	0.502127 (rank : 40)	θ value	5.44631e-05 (rank : 61)
Query Neighborhood Hits	333	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

NHRF2_HUMAN
NC score	0.362970 (rank : 41)	θ value	6.87365e-08 (rank : 37)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	126
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NHRF2_MOUSE
NC score	0.357498 (rank : 42)	θ value	4.45536e-07 (rank : 39)
Query Neighborhood Hits	333	Target Neighborhood Hits	194	Shared Neighborhood Hits	126
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

NHERF_HUMAN
NC score	0.353478 (rank : 43)	θ value	1.87187e-05 (rank : 54)
Query Neighborhood Hits	333	Target Neighborhood Hits	190	Shared Neighborhood Hits	128
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
NC score	0.353380 (rank : 44)	θ value	1.43324e-05 (rank : 48)
Query Neighborhood Hits	333	Target Neighborhood Hits	195	Shared Neighborhood Hits	125
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD1_HUMAN
NC score	0.351492 (rank : 45)	θ value	1.43324e-05 (rank : 49)
Query Neighborhood Hits	333	Target Neighborhood Hits	190	Shared Neighborhood Hits	125
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PDZD1_MOUSE
NC score	0.346596 (rank : 46)	θ value	9.29e-05 (rank : 66)
Query Neighborhood Hits	333	Target Neighborhood Hits	191	Shared Neighborhood Hits	125
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LIN7A_MOUSE
NC score	0.345521 (rank : 47)	θ value	0.000461057 (rank : 74)
Query Neighborhood Hits	333	Target Neighborhood Hits	193	Shared Neighborhood Hits	133
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

LIN7C_HUMAN
NC score	0.345424 (rank : 48)	θ value	1.43324e-05 (rank : 46)
Query Neighborhood Hits	333	Target Neighborhood Hits	198	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.345424 (rank : 49)	θ value	1.43324e-05 (rank : 47)
Query Neighborhood Hits	333	Target Neighborhood Hits	198	Shared Neighborhood Hits	134
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7A_HUMAN
NC score	0.345204 (rank : 50)	θ value	0.000461057 (rank : 73)
Query Neighborhood Hits	333	Target Neighborhood Hits	193	Shared Neighborhood Hits	133
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7B_HUMAN
NC score	0.344941 (rank : 51)	θ value	2.44474e-05 (rank : 57)
Query Neighborhood Hits	333	Target Neighborhood Hits	200	Shared Neighborhood Hits	133
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
NC score	0.344173 (rank : 52)	θ value	3.19293e-05 (rank : 59)
Query Neighborhood Hits	333	Target Neighborhood Hits	200	Shared Neighborhood Hits	133
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

WHRN_HUMAN
NC score	0.331961 (rank : 53)	θ value	7.1131e-05 (rank : 64)
Query Neighborhood Hits	333	Target Neighborhood Hits	325	Shared Neighborhood Hits	147
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
NC score	0.331810 (rank : 54)	θ value	7.1131e-05 (rank : 65)
Query Neighborhood Hits	333	Target Neighborhood Hits	412	Shared Neighborhood Hits	151
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD3_HUMAN
NC score	0.320356 (rank : 55)	θ value	0.0193708 (rank : 106)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	122
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD3_MOUSE
NC score	0.319114 (rank : 56)	θ value	0.00228821 (rank : 82)
Query Neighborhood Hits	333	Target Neighborhood Hits	171	Shared Neighborhood Hits	118
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

USH1C_HUMAN
NC score	0.318165 (rank : 57)	θ value	0.00390308 (rank : 89)
Query Neighborhood Hits	333	Target Neighborhood Hits	327	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

PDZD7_HUMAN
NC score	0.312237 (rank : 58)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	126
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

GRIP2_HUMAN
NC score	0.310523 (rank : 59)	θ value	0.000270298 (rank : 69)
Query Neighborhood Hits	333	Target Neighborhood Hits	256	Shared Neighborhood Hits	136
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

INADL_MOUSE
NC score	0.307525 (rank : 60)	θ value	0.000786445 (rank : 77)
Query Neighborhood Hits	333	Target Neighborhood Hits	290	Shared Neighborhood Hits	136
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

PDZ11_MOUSE
NC score	0.307239 (rank : 61)	θ value	0.0431538 (rank : 120)
Query Neighborhood Hits	333	Target Neighborhood Hits	154	Shared Neighborhood Hits	115
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_HUMAN
NC score	0.306534 (rank : 62)	θ value	0.0961366 (rank : 130)
Query Neighborhood Hits	333	Target Neighborhood Hits	160	Shared Neighborhood Hits	120
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

GRIP1_HUMAN
NC score	0.305333 (rank : 63)	θ value	0.00035302 (rank : 71)
Query Neighborhood Hits	333	Target Neighborhood Hits	231	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y3R0	Gene names	GRIP1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

MAGI1_MOUSE
NC score	0.305228 (rank : 64)	θ value	2.88788e-06 (rank : 42)
Query Neighborhood Hits	333	Target Neighborhood Hits	403	Shared Neighborhood Hits	141
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

GRIP1_MOUSE
NC score	0.304968 (rank : 65)	θ value	0.00035302 (rank : 72)
Query Neighborhood Hits	333	Target Neighborhood Hits	241	Shared Neighborhood Hits	136
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

INADL_HUMAN
NC score	0.303124 (rank : 66)	θ value	0.000602161 (rank : 75)
Query Neighborhood Hits	333	Target Neighborhood Hits	260	Shared Neighborhood Hits	132
SwissProt Accessions	Q8NI35, O15249, O43742, O60833, Q5VUA5, Q5VUA6, Q5VUA7, Q5VUA8, Q5VUA9, Q5VUB0, Q8WU78, Q9H3N9	Gene names	INADL, PATJ
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (hINADL) (Pals1-associated tight junction protein) (Protein associated to tight junctions).

MPDZ_HUMAN
NC score	0.302840 (rank : 67)	θ value	0.000158464 (rank : 68)
Query Neighborhood Hits	333	Target Neighborhood Hits	261	Shared Neighborhood Hits	133
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
NC score	0.302463 (rank : 68)	θ value	0.000270298 (rank : 70)
Query Neighborhood Hits	333	Target Neighborhood Hits	298	Shared Neighborhood Hits	135
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

USH1C_MOUSE
NC score	0.302436 (rank : 69)	θ value	0.00390308 (rank : 90)
Query Neighborhood Hits	333	Target Neighborhood Hits	557	Shared Neighborhood Hits	146
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

GOPC_MOUSE
NC score	0.299419 (rank : 70)	θ value	0.00134147 (rank : 81)
Query Neighborhood Hits	333	Target Neighborhood Hits	323	Shared Neighborhood Hits	120
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

MAGI1_HUMAN
NC score	0.298534 (rank : 71)	θ value	2.44474e-05 (rank : 58)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	141
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

SYJ2B_HUMAN
NC score	0.296020 (rank : 72)	θ value	4.03905 (rank : 259)
Query Neighborhood Hits	333	Target Neighborhood Hits	162	Shared Neighborhood Hits	119
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

GOPC_HUMAN
NC score	0.295722 (rank : 73)	θ value	0.000786445 (rank : 76)
Query Neighborhood Hits	333	Target Neighborhood Hits	377	Shared Neighborhood Hits	121
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

DLG4_MOUSE
NC score	0.291836 (rank : 74)	θ value	2.21117e-06 (rank : 41)
Query Neighborhood Hits	333	Target Neighborhood Hits	282	Shared Neighborhood Hits	131
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.291400 (rank : 75)	θ value	2.21117e-06 (rank : 40)
Query Neighborhood Hits	333	Target Neighborhood Hits	286	Shared Neighborhood Hits	130
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

SNX13_MOUSE
NC score	0.288621 (rank : 76)	θ value	1.87187e-05 (rank : 56)
Query Neighborhood Hits	333	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PHS6	Gene names	Snx13
Domain Architecture	No domain graphic available
Description	Sorting nexin-13.

SNTG2_HUMAN
NC score	0.286970 (rank : 77)	θ value	0.0148317 (rank : 102)
Query Neighborhood Hits	333	Target Neighborhood Hits	191	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NY99	Gene names	SNTG2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

AKA10_MOUSE
NC score	0.286869 (rank : 78)	θ value	0.00390308 (rank : 87)
Query Neighborhood Hits	333	Target Neighborhood Hits	75	Shared Neighborhood Hits	37
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

DLG1_HUMAN
NC score	0.286791 (rank : 79)	θ value	1.87187e-05 (rank : 50)
Query Neighborhood Hits	333	Target Neighborhood Hits	290	Shared Neighborhood Hits	126
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

SNTG1_MOUSE
NC score	0.286221 (rank : 80)	θ value	0.00228821 (rank : 84)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	128
SwissProt Accessions	Q925E1, Q9D3Z5	Gene names	Sntg1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

DLG1_MOUSE
NC score	0.286169 (rank : 81)	θ value	1.87187e-05 (rank : 51)
Query Neighborhood Hits	333	Target Neighborhood Hits	285	Shared Neighborhood Hits	127
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

SNTB2_HUMAN
NC score	0.285887 (rank : 82)	θ value	0.00390308 (rank : 88)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	120
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

DLG3_MOUSE
NC score	0.285311 (rank : 83)	θ value	1.87187e-05 (rank : 53)
Query Neighborhood Hits	333	Target Neighborhood Hits	274	Shared Neighborhood Hits	126
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

SNTG1_HUMAN
NC score	0.285164 (rank : 84)	θ value	0.00298849 (rank : 85)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NSN8, Q9NY98	Gene names	SNTG1
Domain Architecture
Description	Gamma-1-syntrophin (G1SYN) (Syntrophin 4) (SYN4).

SNTB2_MOUSE
NC score	0.284725 (rank : 85)	θ value	0.00665767 (rank : 93)
Query Neighborhood Hits	333	Target Neighborhood Hits	181	Shared Neighborhood Hits	118
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

DLG3_HUMAN
NC score	0.284089 (rank : 86)	θ value	1.87187e-05 (rank : 52)
Query Neighborhood Hits	333	Target Neighborhood Hits	269	Shared Neighborhood Hits	127
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

AKA10_HUMAN
NC score	0.283339 (rank : 87)	θ value	0.0148317 (rank : 99)
Query Neighborhood Hits	333	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	O43572, Q96AJ7	Gene names	AKAP10
Domain Architecture
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

DLG2_MOUSE
NC score	0.282800 (rank : 88)	θ value	5.44631e-05 (rank : 63)
Query Neighborhood Hits	333	Target Neighborhood Hits	271	Shared Neighborhood Hits	127
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

SNX13_HUMAN
NC score	0.282052 (rank : 89)	θ value	9.29e-05 (rank : 67)
Query Neighborhood Hits	333	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5W8, O94821, Q8WVZ2, Q8WXH8	Gene names	SNX13, KIAA0713
Domain Architecture
Description	Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1).

DLG2_HUMAN
NC score	0.282003 (rank : 90)	θ value	5.44631e-05 (rank : 62)
Query Neighborhood Hits	333	Target Neighborhood Hits	279	Shared Neighborhood Hits	128
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

MAGI2_HUMAN
NC score	0.281813 (rank : 91)	θ value	0.0431538 (rank : 118)
Query Neighborhood Hits	333	Target Neighborhood Hits	373	Shared Neighborhood Hits	145
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

RHPN1_MOUSE
NC score	0.280798 (rank : 92)	θ value	4.92598e-06 (rank : 43)
Query Neighborhood Hits	333	Target Neighborhood Hits	154	Shared Neighborhood Hits	116
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

MAGI2_MOUSE
NC score	0.278789 (rank : 93)	θ value	0.0431538 (rank : 119)
Query Neighborhood Hits	333	Target Neighborhood Hits	370	Shared Neighborhood Hits	144
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

SNTG2_MOUSE
NC score	0.276899 (rank : 94)	θ value	0.00665767 (rank : 94)
Query Neighborhood Hits	333	Target Neighborhood Hits	176	Shared Neighborhood Hits	126
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

TX1B3_HUMAN
NC score	0.270769 (rank : 95)	θ value	1.38821 (rank : 193)
Query Neighborhood Hits	333	Target Neighborhood Hits	161	Shared Neighborhood Hits	121
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
NC score	0.270257 (rank : 96)	θ value	1.38821 (rank : 194)
Query Neighborhood Hits	333	Target Neighborhood Hits	158	Shared Neighborhood Hits	120
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PARD3_MOUSE
NC score	0.268924 (rank : 97)	θ value	0.0252991 (rank : 108)
Query Neighborhood Hits	333	Target Neighborhood Hits	290	Shared Neighborhood Hits	120
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

SNTA1_HUMAN
NC score	0.268887 (rank : 98)	θ value	0.0431538 (rank : 121)
Query Neighborhood Hits	333	Target Neighborhood Hits	186	Shared Neighborhood Hits	129
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

SNTB1_MOUSE
NC score	0.268309 (rank : 99)	θ value	0.0252991 (rank : 110)
Query Neighborhood Hits	333	Target Neighborhood Hits	160	Shared Neighborhood Hits	117
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTA1_MOUSE
NC score	0.267475 (rank : 100)	θ value	0.0563607 (rank : 122)
Query Neighborhood Hits	333	Target Neighborhood Hits	170	Shared Neighborhood Hits	125
SwissProt Accessions	Q61234, Q8VEF3	Gene names	Snta1, Snt1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin 1).

PARD3_HUMAN
NC score	0.266687 (rank : 101)	θ value	0.0330416 (rank : 112)
Query Neighborhood Hits	333	Target Neighborhood Hits	312	Shared Neighborhood Hits	118
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

RHPN1_HUMAN
NC score	0.266395 (rank : 102)	θ value	1.87187e-05 (rank : 55)
Query Neighborhood Hits	333	Target Neighborhood Hits	158	Shared Neighborhood Hits	113
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

SNTB1_HUMAN
NC score	0.265602 (rank : 103)	θ value	0.0736092 (rank : 126)
Query Neighborhood Hits	333	Target Neighborhood Hits	157	Shared Neighborhood Hits	117
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

PDZD2_HUMAN
NC score	0.260185 (rank : 104)	θ value	0.163984 (rank : 138)
Query Neighborhood Hits	333	Target Neighborhood Hits	772	Shared Neighborhood Hits	167
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PAR3L_HUMAN
NC score	0.255802 (rank : 105)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	333	Target Neighborhood Hits	297	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

ZO3_MOUSE
NC score	0.243784 (rank : 106)	θ value	0.0330416 (rank : 114)
Query Neighborhood Hits	333	Target Neighborhood Hits	224	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

GRASP_HUMAN
NC score	0.243285 (rank : 107)	θ value	0.0431538 (rank : 116)
Query Neighborhood Hits	333	Target Neighborhood Hits	147	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

GRASP_MOUSE
NC score	0.242365 (rank : 108)	θ value	0.0431538 (rank : 117)
Query Neighborhood Hits	333	Target Neighborhood Hits	131	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

LNX1_MOUSE
NC score	0.240493 (rank : 109)	θ value	0.365318 (rank : 152)
Query Neighborhood Hits	333	Target Neighborhood Hits	377	Shared Neighborhood Hits	124
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

ZO3_HUMAN
NC score	0.239807 (rank : 110)	θ value	0.00509761 (rank : 91)
Query Neighborhood Hits	333	Target Neighborhood Hits	219	Shared Neighborhood Hits	132
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

LNX2_MOUSE
NC score	0.239440 (rank : 111)	θ value	6.88961 (rank : 301)
Query Neighborhood Hits	333	Target Neighborhood Hits	407	Shared Neighborhood Hits	129
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX2_HUMAN
NC score	0.239333 (rank : 112)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	333	Target Neighborhood Hits	389	Shared Neighborhood Hits	130
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

IL16_HUMAN
NC score	0.234257 (rank : 113)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	333	Target Neighborhood Hits	207	Shared Neighborhood Hits	110
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

LNX1_HUMAN
NC score	0.232964 (rank : 114)	θ value	1.38821 (rank : 189)
Query Neighborhood Hits	333	Target Neighborhood Hits	379	Shared Neighborhood Hits	121
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

SYP2L_HUMAN
NC score	0.225880 (rank : 115)	θ value	0.00869519 (rank : 96)
Query Neighborhood Hits	333	Target Neighborhood Hits	400	Shared Neighborhood Hits	128
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

IL16_MOUSE
NC score	0.221182 (rank : 116)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	333	Target Neighborhood Hits	189	Shared Neighborhood Hits	106
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PSCBP_MOUSE
NC score	0.210808 (rank : 117)	θ value	0.62314 (rank : 165)
Query Neighborhood Hits	333	Target Neighborhood Hits	118	Shared Neighborhood Hits	106
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PDLI2_MOUSE
NC score	0.209404 (rank : 118)	θ value	0.0193708 (rank : 105)
Query Neighborhood Hits	333	Target Neighborhood Hits	220	Shared Neighborhood Hits	110
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

APBA1_HUMAN
NC score	0.207607 (rank : 119)	θ value	0.0148317 (rank : 100)
Query Neighborhood Hits	333	Target Neighborhood Hits	325	Shared Neighborhood Hits	128
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

ARHGB_HUMAN
NC score	0.206174 (rank : 120)	θ value	4.1701e-05 (rank : 60)
Query Neighborhood Hits	333	Target Neighborhood Hits	375	Shared Neighborhood Hits	144
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

K1849_HUMAN
NC score	0.205749 (rank : 121)	θ value	0.47712 (rank : 156)
Query Neighborhood Hits	333	Target Neighborhood Hits	220	Shared Neighborhood Hits	115
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

ZO2_HUMAN
NC score	0.205722 (rank : 122)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	333	Target Neighborhood Hits	289	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO1_MOUSE
NC score	0.204930 (rank : 123)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	333	Target Neighborhood Hits	453	Shared Neighborhood Hits	145
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

K1849_MOUSE
NC score	0.204297 (rank : 124)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	333	Target Neighborhood Hits	335	Shared Neighborhood Hits	150
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

APBA2_MOUSE
NC score	0.202367 (rank : 125)	θ value	0.0113563 (rank : 98)
Query Neighborhood Hits	333	Target Neighborhood Hits	219	Shared Neighborhood Hits	115
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

ZO1_HUMAN
NC score	0.201804 (rank : 126)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	333	Target Neighborhood Hits	474	Shared Neighborhood Hits	134
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_MOUSE
NC score	0.199945 (rank : 127)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	333	Target Neighborhood Hits	296	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

APBA2_HUMAN
NC score	0.198958 (rank : 128)	θ value	0.0113563 (rank : 97)
Query Neighborhood Hits	333	Target Neighborhood Hits	220	Shared Neighborhood Hits	110
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

LAP4_HUMAN
NC score	0.196366 (rank : 129)	θ value	0.000786445 (rank : 78)
Query Neighborhood Hits	333	Target Neighborhood Hits	608	Shared Neighborhood Hits	148
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

SYNP2_MOUSE
NC score	0.195940 (rank : 130)	θ value	0.0148317 (rank : 103)
Query Neighborhood Hits	333	Target Neighborhood Hits	252	Shared Neighborhood Hits	115
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

PDLI2_HUMAN
NC score	0.193590 (rank : 131)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	111
SwissProt Accessions	Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2	Gene names	PDLIM2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).

SDCB1_MOUSE
NC score	0.190815 (rank : 132)	θ value	1.06291 (rank : 181)
Query Neighborhood Hits	333	Target Neighborhood Hits	144	Shared Neighborhood Hits	109
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

LAP4_MOUSE
NC score	0.188391 (rank : 133)	θ value	0.163984 (rank : 134)
Query Neighborhood Hits	333	Target Neighborhood Hits	590	Shared Neighborhood Hits	145
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

ARHGC_MOUSE
NC score	0.187209 (rank : 134)	θ value	0.00102713 (rank : 80)
Query Neighborhood Hits	333	Target Neighborhood Hits	344	Shared Neighborhood Hits	124
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PSCBP_HUMAN
NC score	0.186737 (rank : 135)	θ value	4.03905 (rank : 257)
Query Neighborhood Hits	333	Target Neighborhood Hits	123	Shared Neighborhood Hits	102
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

ARHGC_HUMAN
NC score	0.186210 (rank : 136)	θ value	0.00102713 (rank : 79)
Query Neighborhood Hits	333	Target Neighborhood Hits	351	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

SDCB1_HUMAN
NC score	0.186129 (rank : 137)	θ value	1.06291 (rank : 180)
Query Neighborhood Hits	333	Target Neighborhood Hits	150	Shared Neighborhood Hits	109
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

APBA3_HUMAN
NC score	0.185188 (rank : 138)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	333	Target Neighborhood Hits	201	Shared Neighborhood Hits	103
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PZRN4_HUMAN
NC score	0.185086 (rank : 139)	θ value	8.99809 (rank : 330)
Query Neighborhood Hits	333	Target Neighborhood Hits	438	Shared Neighborhood Hits	106
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

PZRN3_MOUSE
NC score	0.184269 (rank : 140)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	333	Target Neighborhood Hits	447	Shared Neighborhood Hits	111
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_HUMAN
NC score	0.183191 (rank : 141)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	333	Target Neighborhood Hits	461	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

AFAD_HUMAN
NC score	0.178781 (rank : 142)	θ value	0.365318 (rank : 149)
Query Neighborhood Hits	333	Target Neighborhood Hits	689	Shared Neighborhood Hits	117
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

APXL_HUMAN
NC score	0.178422 (rank : 143)	θ value	0.62314 (rank : 161)
Query Neighborhood Hits	333	Target Neighborhood Hits	553	Shared Neighborhood Hits	112
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

SHAN2_HUMAN
NC score	0.177903 (rank : 144)	θ value	0.47712 (rank : 159)
Query Neighborhood Hits	333	Target Neighborhood Hits	346	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PTN13_HUMAN
NC score	0.175228 (rank : 145)	θ value	0.00228821 (rank : 83)
Query Neighborhood Hits	333	Target Neighborhood Hits	471	Shared Neighborhood Hits	137
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SYP2L_MOUSE
NC score	0.172167 (rank : 146)	θ value	1.81305 (rank : 210)
Query Neighborhood Hits	333	Target Neighborhood Hits	289	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

PTN13_MOUSE
NC score	0.171416 (rank : 147)	θ value	0.0252991 (rank : 109)
Query Neighborhood Hits	333	Target Neighborhood Hits	426	Shared Neighborhood Hits	136
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

DLG5_HUMAN
NC score	0.169473 (rank : 148)	θ value	0.21417 (rank : 142)
Query Neighborhood Hits	333	Target Neighborhood Hits	1088	Shared Neighborhood Hits	138
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PDLI3_HUMAN
NC score	0.168723 (rank : 149)	θ value	0.0961366 (rank : 129)
Query Neighborhood Hits	333	Target Neighborhood Hits	199	Shared Neighborhood Hits	96
SwissProt Accessions	Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4	Gene names	PDLIM3, ALP
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

MPP4_HUMAN
NC score	0.167922 (rank : 150)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	333	Target Neighborhood Hits	205	Shared Neighborhood Hits	104
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PDLI3_MOUSE
NC score	0.164559 (rank : 151)	θ value	0.00869519 (rank : 95)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	92
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

DVL3_HUMAN
NC score	0.163514 (rank : 152)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	333	Target Neighborhood Hits	194	Shared Neighborhood Hits	94
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL3_MOUSE
NC score	0.163212 (rank : 153)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	333	Target Neighborhood Hits	198	Shared Neighborhood Hits	94
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

APBA3_MOUSE
NC score	0.163155 (rank : 154)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	333	Target Neighborhood Hits	174	Shared Neighborhood Hits	98
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PDLI4_HUMAN
NC score	0.162661 (rank : 155)	θ value	0.163984 (rank : 137)
Query Neighborhood Hits	333	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	P50479, Q96AT8, Q9BTW8, Q9Y292	Gene names	PDLIM4, RIL
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

SDCB2_MOUSE
NC score	0.160737 (rank : 156)	θ value	3.0926 (rank : 244)
Query Neighborhood Hits	333	Target Neighborhood Hits	118	Shared Neighborhood Hits	87
SwissProt Accessions	Q99JZ0	Gene names	Sdcbp2
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SDCB2_HUMAN
NC score	0.158624 (rank : 157)	θ value	3.0926 (rank : 243)
Query Neighborhood Hits	333	Target Neighborhood Hits	121	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H190, O95892, Q5W0X1, Q9BZ42, Q9H567, Q9NRY8	Gene names	SDCBP2, SITAC18
Domain Architecture
Description	Syntenin-2 (Syndecan-binding protein 2).

SYNP2_HUMAN
NC score	0.157827 (rank : 158)	θ value	1.38821 (rank : 192)
Query Neighborhood Hits	333	Target Neighborhood Hits	323	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

PDLI4_MOUSE
NC score	0.156936 (rank : 159)	θ value	0.813845 (rank : 175)
Query Neighborhood Hits	333	Target Neighborhood Hits	233	Shared Neighborhood Hits	101
SwissProt Accessions	P70271, Q8K0W4	Gene names	Pdlim4, Ril
Domain Architecture
Description	PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein).

SHAN2_MOUSE
NC score	0.156586 (rank : 160)	θ value	0.62314 (rank : 169)
Query Neighborhood Hits	333	Target Neighborhood Hits	446	Shared Neighborhood Hits	119
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

DVL1_HUMAN
NC score	0.150708 (rank : 161)	θ value	8.99809 (rank : 317)
Query Neighborhood Hits	333	Target Neighborhood Hits	158	Shared Neighborhood Hits	96
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

MPP5_HUMAN
NC score	0.149892 (rank : 162)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	333	Target Neighborhood Hits	231	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.149398 (rank : 163)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	333	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

RPGF6_HUMAN
NC score	0.149280 (rank : 164)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	333	Target Neighborhood Hits	266	Shared Neighborhood Hits	122
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

MPP4_MOUSE
NC score	0.148127 (rank : 165)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	333	Target Neighborhood Hits	188	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MPP3_MOUSE
NC score	0.147395 (rank : 166)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	90
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP3_HUMAN
NC score	0.147210 (rank : 167)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	333	Target Neighborhood Hits	171	Shared Neighborhood Hits	90
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

DVL1_MOUSE
NC score	0.147196 (rank : 168)	θ value	8.99809 (rank : 318)
Query Neighborhood Hits	333	Target Neighborhood Hits	146	Shared Neighborhood Hits	90
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DVL2_MOUSE
NC score	0.145409 (rank : 169)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	333	Target Neighborhood Hits	233	Shared Neighborhood Hits	110
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DVL2_HUMAN
NC score	0.144681 (rank : 170)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	333	Target Neighborhood Hits	223	Shared Neighborhood Hits	102
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

PDLI1_MOUSE
NC score	0.144285 (rank : 171)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	333	Target Neighborhood Hits	213	Shared Neighborhood Hits	91
SwissProt Accessions	O70400, Q99K93	Gene names	Pdlim1, Clim1
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

DVL1L_HUMAN
NC score	0.144075 (rank : 172)	θ value	8.99809 (rank : 316)
Query Neighborhood Hits	333	Target Neighborhood Hits	146	Shared Neighborhood Hits	90
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

PDLI1_HUMAN
NC score	0.139974 (rank : 173)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	333	Target Neighborhood Hits	242	Shared Neighborhood Hits	91
SwissProt Accessions	O00151, Q5VZH5, Q9BPZ9	Gene names	PDLIM1, CLIM1, CLP36
Domain Architecture
Description	PDZ and LIM domain protein 1 (Elfin) (LIM domain protein CLP-36) (C- terminal LIM domain protein 1).

NOS1_HUMAN
NC score	0.138973 (rank : 174)	θ value	0.279714 (rank : 146)
Query Neighborhood Hits	333	Target Neighborhood Hits	218	Shared Neighborhood Hits	114
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PICK1_HUMAN
NC score	0.138861 (rank : 175)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	333	Target Neighborhood Hits	132	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRD5, O95906	Gene names	PICK1, PRKCABP
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PICK1_MOUSE
NC score	0.138440 (rank : 176)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	333	Target Neighborhood Hits	131	Shared Neighborhood Hits	87
SwissProt Accessions	Q62083	Gene names	Pick1, Prkcabp
Domain Architecture
Description	PRKCA-binding protein (Protein kinase C-alpha-binding protein) (Protein interacting with C kinase 1).

PAR6G_HUMAN
NC score	0.131248 (rank : 177)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	333	Target Neighborhood Hits	159	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

RPGF2_HUMAN
NC score	0.130258 (rank : 178)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	333	Target Neighborhood Hits	242	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SNX25_HUMAN
NC score	0.128522 (rank : 179)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	333	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

PDLI5_HUMAN
NC score	0.126649 (rank : 180)	θ value	0.0148317 (rank : 101)
Query Neighborhood Hits	333	Target Neighborhood Hits	322	Shared Neighborhood Hits	115
SwissProt Accessions	Q96HC4, O60705	Gene names	PDLIM5, ENH
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

NOS1_MOUSE
NC score	0.126579 (rank : 181)	θ value	0.0961366 (rank : 128)
Query Neighborhood Hits	333	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

EM55_HUMAN
NC score	0.125909 (rank : 182)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	333	Target Neighborhood Hits	228	Shared Neighborhood Hits	83
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

PAR6G_MOUSE
NC score	0.125785 (rank : 183)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	333	Target Neighborhood Hits	121	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JK84	Gene names	Pard6g, Par6g
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A).

PAR6B_MOUSE
NC score	0.125766 (rank : 184)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	333	Target Neighborhood Hits	128	Shared Neighborhood Hits	85
SwissProt Accessions	Q9JK83, Q8R3J8	Gene names	Pard6b, Par6b
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

NEB1_HUMAN
NC score	0.125758 (rank : 185)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	333	Target Neighborhood Hits	829	Shared Neighborhood Hits	100
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PAR6B_HUMAN
NC score	0.125237 (rank : 186)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	333	Target Neighborhood Hits	126	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

PDLI5_MOUSE
NC score	0.122867 (rank : 187)	θ value	0.0736092 (rank : 125)
Query Neighborhood Hits	333	Target Neighborhood Hits	287	Shared Neighborhood Hits	110
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

STXB4_HUMAN
NC score	0.122797 (rank : 188)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	333	Target Neighborhood Hits	616	Shared Neighborhood Hits	84
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

EM55_MOUSE
NC score	0.122624 (rank : 189)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	333	Target Neighborhood Hits	221	Shared Neighborhood Hits	82
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

NEB2_MOUSE
NC score	0.120267 (rank : 190)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	333	Target Neighborhood Hits	889	Shared Neighborhood Hits	98
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_HUMAN
NC score	0.120242 (rank : 191)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	333	Target Neighborhood Hits	883	Shared Neighborhood Hits	94
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

STXB4_MOUSE
NC score	0.120013 (rank : 192)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	333	Target Neighborhood Hits	629	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

LDB3_HUMAN
NC score	0.119622 (rank : 193)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	333	Target Neighborhood Hits	497	Shared Neighborhood Hits	119
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LDB3_MOUSE
NC score	0.116009 (rank : 194)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	333	Target Neighborhood Hits	510	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PDLI7_HUMAN
NC score	0.115300 (rank : 195)	θ value	1.06291 (rank : 179)
Query Neighborhood Hits	333	Target Neighborhood Hits	547	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PAR6A_MOUSE
NC score	0.114497 (rank : 196)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	333	Target Neighborhood Hits	115	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z101, Q5RL03, Q6P8R2	Gene names	Pard6a, Par6a
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6).

PAR6A_HUMAN
NC score	0.113832 (rank : 197)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	333	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NPB6, O14911, Q9NPJ7	Gene names	PARD6A, PAR6A
Domain Architecture
Description	Partitioning defective 6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40).

RHPN2_MOUSE
NC score	0.113719 (rank : 198)	θ value	0.279714 (rank : 148)
Query Neighborhood Hits	333	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

PDZK4_HUMAN
NC score	0.113359 (rank : 199)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	85
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PDZK4_MOUSE
NC score	0.113346 (rank : 200)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	333	Target Neighborhood Hits	165	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SHAN1_HUMAN
NC score	0.111690 (rank : 201)	θ value	1.06291 (rank : 182)
Query Neighborhood Hits	333	Target Neighborhood Hits	1041	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

MPP6_MOUSE
NC score	0.110247 (rank : 202)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	333	Target Neighborhood Hits	187	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP2_MOUSE
NC score	0.109831 (rank : 203)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	333	Target Neighborhood Hits	189	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

RIMS1_HUMAN
NC score	0.108820 (rank : 204)	θ value	0.813845 (rank : 176)
Query Neighborhood Hits	333	Target Neighborhood Hits	437	Shared Neighborhood Hits	104
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

MPP2_HUMAN
NC score	0.107722 (rank : 205)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	333	Target Neighborhood Hits	173	Shared Neighborhood Hits	67
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP6_HUMAN
NC score	0.106719 (rank : 206)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	333	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

PDLI7_MOUSE
NC score	0.106362 (rank : 207)	θ value	8.99809 (rank : 329)
Query Neighborhood Hits	333	Target Neighborhood Hits	279	Shared Neighborhood Hits	91
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PCLO_MOUSE
NC score	0.102854 (rank : 208)	θ value	1.81305 (rank : 207)
Query Neighborhood Hits	333	Target Neighborhood Hits	2275	Shared Neighborhood Hits	192
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RHPN2_HUMAN
NC score	0.093334 (rank : 209)	θ value	0.163984 (rank : 140)
Query Neighborhood Hits	333	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RIMS2_HUMAN
NC score	0.091347 (rank : 210)	θ value	0.62314 (rank : 166)
Query Neighborhood Hits	333	Target Neighborhood Hits	342	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.090565 (rank : 211)	θ value	0.62314 (rank : 167)
Query Neighborhood Hits	333	Target Neighborhood Hits	376	Shared Neighborhood Hits	85
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

KGUA_MOUSE
NC score	0.085762 (rank : 212)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	333	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_HUMAN
NC score	0.084904 (rank : 213)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	333	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

LRRC7_HUMAN
NC score	0.083048 (rank : 214)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	333	Target Neighborhood Hits	423	Shared Neighborhood Hits	101
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

LRRC7_MOUSE
NC score	0.082054 (rank : 215)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	333	Target Neighborhood Hits	416	Shared Neighborhood Hits	98
SwissProt Accessions	Q80TE7	Gene names	Lrrc7, Kiaa1365, Lap1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

PTN4_HUMAN
NC score	0.080831 (rank : 216)	θ value	0.279714 (rank : 147)
Query Neighborhood Hits	333	Target Neighborhood Hits	303	Shared Neighborhood Hits	105
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN3_HUMAN
NC score	0.079204 (rank : 217)	θ value	0.47712 (rank : 158)
Query Neighborhood Hits	333	Target Neighborhood Hits	258	Shared Neighborhood Hits	103
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

CO3A1_HUMAN
NC score	0.075529 (rank : 218)	θ value	0.0961366 (rank : 127)
Query Neighborhood Hits	333	Target Neighborhood Hits	452	Shared Neighborhood Hits	60
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

LAP2_HUMAN
NC score	0.075092 (rank : 219)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	333	Target Neighborhood Hits	499	Shared Neighborhood Hits	85
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

CO3A1_MOUSE
NC score	0.073749 (rank : 220)	θ value	0.163984 (rank : 132)
Query Neighborhood Hits	333	Target Neighborhood Hits	466	Shared Neighborhood Hits	61
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

LMO7_HUMAN
NC score	0.073617 (rank : 221)	θ value	0.163984 (rank : 135)
Query Neighborhood Hits	333	Target Neighborhood Hits	507	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

GIPC1_MOUSE
NC score	0.072790 (rank : 222)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	333	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0G0	Gene names	Gipc1, Gipc, Rgs19ip1, Semcap1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Synectin) (SemaF cytoplasmic domain-associated protein 1) (SEMCAP-1).

CN032_MOUSE
NC score	0.071846 (rank : 223)	θ value	0.125558 (rank : 131)
Query Neighborhood Hits	333	Target Neighborhood Hits	233	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CO1A1_MOUSE
NC score	0.071513 (rank : 224)	θ value	0.62314 (rank : 163)
Query Neighborhood Hits	333	Target Neighborhood Hits	457	Shared Neighborhood Hits	63
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

LAP2_MOUSE
NC score	0.071048 (rank : 225)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	333	Target Neighborhood Hits	482	Shared Neighborhood Hits	87
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

CO4A5_HUMAN
NC score	0.069586 (rank : 226)	θ value	0.365318 (rank : 150)
Query Neighborhood Hits	333	Target Neighborhood Hits	383	Shared Neighborhood Hits	60
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

CO1A1_HUMAN
NC score	0.069335 (rank : 227)	θ value	1.38821 (rank : 186)
Query Neighborhood Hits	333	Target Neighborhood Hits	475	Shared Neighborhood Hits	64
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

GIPC1_HUMAN
NC score	0.067860 (rank : 228)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	333	Target Neighborhood Hits	91	Shared Neighborhood Hits	61
SwissProt Accessions	O14908, Q9BTC9	Gene names	GIPC1, C19orf3, GIPC, RGS19IP1
Domain Architecture
Description	PDZ domain-containing protein GIPC1 (RGS19-interacting protein 1) (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (Tax interaction protein 2) (TIP-2).

CO4A1_MOUSE
NC score	0.066088 (rank : 229)	θ value	0.0431538 (rank : 115)
Query Neighborhood Hits	333	Target Neighborhood Hits	450	Shared Neighborhood Hits	68
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

COHA1_HUMAN
NC score	0.064490 (rank : 230)	θ value	6.88961 (rank : 293)
Query Neighborhood Hits	333	Target Neighborhood Hits	400	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MUC1_HUMAN
NC score	0.064382 (rank : 231)	θ value	0.0736092 (rank : 123)
Query Neighborhood Hits	333	Target Neighborhood Hits	975	Shared Neighborhood Hits	91
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PDZD8_HUMAN
NC score	0.064261 (rank : 232)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	333	Target Neighborhood Hits	185	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

SF01_MOUSE
NC score	0.063705 (rank : 233)	θ value	0.365318 (rank : 153)
Query Neighborhood Hits	333	Target Neighborhood Hits	240	Shared Neighborhood Hits	23
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

CO1A2_HUMAN
NC score	0.063544 (rank : 234)	θ value	1.38821 (rank : 187)
Query Neighborhood Hits	333	Target Neighborhood Hits	329	Shared Neighborhood Hits	53
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A2_MOUSE
NC score	0.062918 (rank : 235)	θ value	2.36792 (rank : 215)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	58
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

GIPC2_HUMAN
NC score	0.062462 (rank : 236)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	333	Target Neighborhood Hits	93	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TF65, Q8IYD3, Q9NXS7	Gene names	GIPC2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2.

COHA1_MOUSE
NC score	0.062434 (rank : 237)	θ value	1.81305 (rank : 198)
Query Neighborhood Hits	333	Target Neighborhood Hits	414	Shared Neighborhood Hits	62
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CO5A2_HUMAN
NC score	0.062043 (rank : 238)	θ value	0.813845 (rank : 171)
Query Neighborhood Hits	333	Target Neighborhood Hits	760	Shared Neighborhood Hits	79
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO2A1_MOUSE
NC score	0.061940 (rank : 239)	θ value	4.03905 (rank : 247)
Query Neighborhood Hits	333	Target Neighborhood Hits	483	Shared Neighborhood Hits	63
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO2A1_HUMAN
NC score	0.061937 (rank : 240)	θ value	3.0926 (rank : 227)
Query Neighborhood Hits	333	Target Neighborhood Hits	486	Shared Neighborhood Hits	68
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

PRR12_HUMAN
NC score	0.061769 (rank : 241)	θ value	3.0926 (rank : 242)
Query Neighborhood Hits	333	Target Neighborhood Hits	460	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CO4A4_HUMAN
NC score	0.061579 (rank : 242)	θ value	2.36792 (rank : 217)
Query Neighborhood Hits	333	Target Neighborhood Hits	440	Shared Neighborhood Hits	69
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

PRP2_MOUSE
NC score	0.061076 (rank : 243)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	333	Target Neighborhood Hits	347	Shared Neighborhood Hits	43
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SF01_HUMAN
NC score	0.061020 (rank : 244)	θ value	0.62314 (rank : 168)
Query Neighborhood Hits	333	Target Neighborhood Hits	287	Shared Neighborhood Hits	29
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

PDZD6_HUMAN
NC score	0.059978 (rank : 245)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	333	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

COJA1_HUMAN
NC score	0.059059 (rank : 246)	θ value	1.81305 (rank : 199)
Query Neighborhood Hits	333	Target Neighborhood Hits	323	Shared Neighborhood Hits	54
SwissProt Accessions	Q14993, Q00559, Q05850, Q12885, Q13676, Q5JUF0, Q5T424, Q9H572, Q9NPZ2, Q9NQP2	Gene names	COL19A1
Domain Architecture
Description	Collagen alpha-1(XIX) chain precursor (Collagen alpha-1(Y) chain).

CO4A1_HUMAN
NC score	0.058963 (rank : 247)	θ value	3.0926 (rank : 228)
Query Neighborhood Hits	333	Target Neighborhood Hits	425	Shared Neighborhood Hits	63
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CO4A6_HUMAN
NC score	0.058819 (rank : 248)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	333	Target Neighborhood Hits	318	Shared Neighborhood Hits	53
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CN155_HUMAN
NC score	0.058075 (rank : 249)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	333	Target Neighborhood Hits	385	Shared Neighborhood Hits	39
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

BAT2_HUMAN
NC score	0.057650 (rank : 250)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	333	Target Neighborhood Hits	931	Shared Neighborhood Hits	87
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO4A3_HUMAN
NC score	0.057200 (rank : 251)	θ value	6.88961 (rank : 292)
Query Neighborhood Hits	333	Target Neighborhood Hits	421	Shared Neighborhood Hits	61
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

SPAG8_HUMAN
NC score	0.057060 (rank : 252)	θ value	0.62314 (rank : 170)
Query Neighborhood Hits	333	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q99932, Q12937, Q5TCV8, Q8WWB4	Gene names	SPAG8
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 8 (Sperm membrane protein 1) (SMP-1) (HSD-1) (Sperm membrane protein BS-84).

PRB4S_HUMAN
NC score	0.056994 (rank : 253)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	333	Target Neighborhood Hits	330	Shared Neighborhood Hits	47
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

CO4A2_HUMAN
NC score	0.056465 (rank : 254)	θ value	4.03905 (rank : 248)
Query Neighborhood Hits	333	Target Neighborhood Hits	454	Shared Neighborhood Hits	66
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

PRB3_HUMAN
NC score	0.056458 (rank : 255)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	333	Target Neighborhood Hits	318	Shared Neighborhood Hits	46
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CO4A2_MOUSE
NC score	0.056431 (rank : 256)	θ value	2.36792 (rank : 216)
Query Neighborhood Hits	333	Target Neighborhood Hits	492	Shared Neighborhood Hits	70
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COGA1_HUMAN
NC score	0.055385 (rank : 257)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	333	Target Neighborhood Hits	345	Shared Neighborhood Hits	55
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

CO9A1_MOUSE
NC score	0.055193 (rank : 258)	θ value	0.62314 (rank : 164)
Query Neighborhood Hits	333	Target Neighborhood Hits	477	Shared Neighborhood Hits	68
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO5A1_MOUSE
NC score	0.055120 (rank : 259)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	333	Target Neighborhood Hits	419	Shared Neighborhood Hits	60
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CO9A3_HUMAN
NC score	0.055026 (rank : 260)	θ value	5.27518 (rank : 270)
Query Neighborhood Hits	333	Target Neighborhood Hits	361	Shared Neighborhood Hits	58
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CO5A1_HUMAN
NC score	0.055006 (rank : 261)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	333	Target Neighborhood Hits	434	Shared Neighborhood Hits	61
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CYLC2_HUMAN
NC score	0.054969 (rank : 262)	θ value	0.00665767 (rank : 92)
Query Neighborhood Hits	333	Target Neighborhood Hits	223	Shared Neighborhood Hits	16
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

CO9A2_MOUSE
NC score	0.054507 (rank : 263)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	333	Target Neighborhood Hits	279	Shared Neighborhood Hits	56
SwissProt Accessions	Q07643	Gene names	Col9a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

COAA1_HUMAN
NC score	0.054287 (rank : 264)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	333	Target Neighborhood Hits	316	Shared Neighborhood Hits	59
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

PRP1_HUMAN
NC score	0.054235 (rank : 265)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	333	Target Neighborhood Hits	385	Shared Neighborhood Hits	51
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CO9A1_HUMAN
NC score	0.053536 (rank : 266)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	333	Target Neighborhood Hits	420	Shared Neighborhood Hits	62
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ELN_HUMAN
NC score	0.051817 (rank : 267)	θ value	8.99809 (rank : 319)
Query Neighborhood Hits	333	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	P15502, O15336, O15337, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5	Gene names	ELN
Domain Architecture	No domain graphic available
Description	Elastin precursor (Tropoelastin).

COBA2_HUMAN
NC score	0.051752 (rank : 268)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	333	Target Neighborhood Hits	408	Shared Neighborhood Hits	58
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COIA1_HUMAN
NC score	0.051654 (rank : 269)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	333	Target Neighborhood Hits	447	Shared Neighborhood Hits	63
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COBA1_HUMAN
NC score	0.051503 (rank : 270)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	333	Target Neighborhood Hits	491	Shared Neighborhood Hits	67
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

EMID2_HUMAN
NC score	0.051212 (rank : 271)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	333	Target Neighborhood Hits	226	Shared Neighborhood Hits	49
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

NCOA6_HUMAN
NC score	0.050934 (rank : 272)	θ value	0.163984 (rank : 136)
Query Neighborhood Hits	333	Target Neighborhood Hits	1202	Shared Neighborhood Hits	94
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CONA1_HUMAN
NC score	0.050843 (rank : 273)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	333	Target Neighborhood Hits	281	Shared Neighborhood Hits	51
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CO9A2_HUMAN
NC score	0.050841 (rank : 274)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	333	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	Q14055	Gene names	COL9A2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(IX) chain precursor.

CO5A3_HUMAN
NC score	0.050782 (rank : 275)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	333	Target Neighborhood Hits	433	Shared Neighborhood Hits	61
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

COBA1_MOUSE
NC score	0.050570 (rank : 276)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	333	Target Neighborhood Hits	487	Shared Neighborhood Hits	66
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

SNX14_MOUSE
NC score	0.050065 (rank : 277)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	333	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHY8	Gene names	Snx14
Domain Architecture	No domain graphic available
Description	Sorting nexin-14.

OGFR_HUMAN
NC score	0.048998 (rank : 278)	θ value	1.38821 (rank : 191)
Query Neighborhood Hits	333	Target Neighborhood Hits	1582	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SON_HUMAN
NC score	0.048672 (rank : 279)	θ value	1.06291 (rank : 183)
Query Neighborhood Hits	333	Target Neighborhood Hits	1568	Shared Neighborhood Hits	115
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DP13A_HUMAN
NC score	0.048407 (rank : 280)	θ value	0.0193708 (rank : 104)
Query Neighborhood Hits	333	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
NC score	0.048343 (rank : 281)	θ value	0.0252991 (rank : 107)
Query Neighborhood Hits	333	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

BAT2_MOUSE
NC score	0.047883 (rank : 282)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	333	Target Neighborhood Hits	947	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO7A1_HUMAN
NC score	0.047392 (rank : 283)	θ value	1.81305 (rank : 197)
Query Neighborhood Hits	333	Target Neighborhood Hits	807	Shared Neighborhood Hits	77
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

BCL9_HUMAN
NC score	0.046303 (rank : 284)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	333	Target Neighborhood Hits	1008	Shared Neighborhood Hits	99
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

NCOA6_MOUSE
NC score	0.045725 (rank : 285)	θ value	8.99809 (rank : 326)
Query Neighborhood Hits	333	Target Neighborhood Hits	1076	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

GPSM2_HUMAN
NC score	0.044351 (rank : 286)	θ value	0.279714 (rank : 145)
Query Neighborhood Hits	333	Target Neighborhood Hits	55	Shared Neighborhood Hits	7
SwissProt Accessions	P81274, Q8N0Z5	Gene names	GPSM2, LGN
Domain Architecture
Description	G-protein signaling modulator 2 (Mosaic protein LGN).

TAF4_HUMAN
NC score	0.043829 (rank : 287)	θ value	6.88961 (rank : 306)
Query Neighborhood Hits	333	Target Neighborhood Hits	687	Shared Neighborhood Hits	53
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

GPSM1_MOUSE
NC score	0.043762 (rank : 288)	θ value	0.163984 (rank : 133)
Query Neighborhood Hits	333	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IR34, Q61366, Q8BUK4, Q8BX78, Q8R0R9	Gene names	Gpsm1, Ags3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

NACAM_MOUSE
NC score	0.042404 (rank : 289)	θ value	0.47712 (rank : 157)
Query Neighborhood Hits	333	Target Neighborhood Hits	1866	Shared Neighborhood Hits	106
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MARCO_MOUSE
NC score	0.041108 (rank : 290)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	333	Target Neighborhood Hits	242	Shared Neighborhood Hits	40
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

SFPQ_MOUSE
NC score	0.040093 (rank : 291)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	333	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

BSN_MOUSE
NC score	0.040015 (rank : 292)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	333	Target Neighborhood Hits	2057	Shared Neighborhood Hits	129
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CTHR1_HUMAN
NC score	0.039460 (rank : 293)	θ value	5.27518 (rank : 274)
Query Neighborhood Hits	333	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

DAB2_HUMAN
NC score	0.039366 (rank : 294)	θ value	0.365318 (rank : 151)
Query Neighborhood Hits	333	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

COEA1_HUMAN
NC score	0.039352 (rank : 295)	θ value	5.27518 (rank : 272)
Query Neighborhood Hits	333	Target Neighborhood Hits	427	Shared Neighborhood Hits	56
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

GPSM1_HUMAN
NC score	0.037861 (rank : 296)	θ value	1.81305 (rank : 202)
Query Neighborhood Hits	333	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q86YR5, Q86SR5, Q969T1, Q9UFS8	Gene names	GPSM1, AGS3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

SMRC2_MOUSE
NC score	0.037719 (rank : 297)	θ value	1.81305 (rank : 209)
Query Neighborhood Hits	333	Target Neighborhood Hits	487	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

GPSM2_MOUSE
NC score	0.036946 (rank : 298)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	333	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VDU0, Q8BLX3	Gene names	Gpsm2, Lgn, Pins
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 2 (Pins homolog).

FXYD5_HUMAN
NC score	0.036823 (rank : 299)	θ value	0.813845 (rank : 172)
Query Neighborhood Hits	333	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DB9, Q6UW44, Q9HC34, Q9P039	Gene names	FXYD5, DYSAD, IWU1
Domain Architecture
Description	FXYD domain-containing ion transport regulator 5 precursor (Dysadherin).

COEA1_MOUSE
NC score	0.036761 (rank : 300)	θ value	5.27518 (rank : 273)
Query Neighborhood Hits	333	Target Neighborhood Hits	402	Shared Neighborhood Hits	53
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

NFH_MOUSE
NC score	0.036367 (rank : 301)	θ value	0.0736092 (rank : 124)
Query Neighborhood Hits	333	Target Neighborhood Hits	2247	Shared Neighborhood Hits	128
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CS007_HUMAN
NC score	0.036211 (rank : 302)	θ value	6.88961 (rank : 294)
Query Neighborhood Hits	333	Target Neighborhood Hits	401	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

EP300_HUMAN
NC score	0.035732 (rank : 303)	θ value	4.03905 (rank : 249)
Query Neighborhood Hits	333	Target Neighborhood Hits	821	Shared Neighborhood Hits	81
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

IRS2_HUMAN
NC score	0.034582 (rank : 304)	θ value	5.27518 (rank : 278)
Query Neighborhood Hits	333	Target Neighborhood Hits	262	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

SMRC2_HUMAN
NC score	0.033609 (rank : 305)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	333	Target Neighborhood Hits	499	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TM108_MOUSE
NC score	0.033602 (rank : 306)	θ value	4.03905 (rank : 261)
Query Neighborhood Hits	333	Target Neighborhood Hits	336	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

IL3B2_MOUSE
NC score	0.032927 (rank : 307)	θ value	1.81305 (rank : 203)
Query Neighborhood Hits	333	Target Neighborhood Hits	372	Shared Neighborhood Hits	48
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

SC24A_MOUSE
NC score	0.032885 (rank : 308)	θ value	1.81305 (rank : 208)
Query Neighborhood Hits	333	Target Neighborhood Hits	394	Shared Neighborhood Hits	40
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

COCA1_HUMAN
NC score	0.032409 (rank : 309)	θ value	5.27518 (rank : 271)
Query Neighborhood Hits	333	Target Neighborhood Hits	458	Shared Neighborhood Hits	50
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MAST4_HUMAN
NC score	0.032343 (rank : 310)	θ value	1.81305 (rank : 204)
Query Neighborhood Hits	333	Target Neighborhood Hits	1804	Shared Neighborhood Hits	167
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MY18A_MOUSE
NC score	0.032316 (rank : 311)	θ value	4.03905 (rank : 255)
Query Neighborhood Hits	333	Target Neighborhood Hits	1989	Shared Neighborhood Hits	129
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

IRS2_MOUSE
NC score	0.032011 (rank : 312)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	333	Target Neighborhood Hits	248	Shared Neighborhood Hits	32
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MAST3_HUMAN
NC score	0.031175 (rank : 313)	θ value	0.21417 (rank : 143)
Query Neighborhood Hits	333	Target Neighborhood Hits	1128	Shared Neighborhood Hits	125
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

HTRA2_HUMAN
NC score	0.030249 (rank : 314)	θ value	1.38821 (rank : 188)
Query Neighborhood Hits	333	Target Neighborhood Hits	30	Shared Neighborhood Hits	17
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

MY18A_HUMAN
NC score	0.029797 (rank : 315)	θ value	4.03905 (rank : 254)
Query Neighborhood Hits	333	Target Neighborhood Hits	1929	Shared Neighborhood Hits	128
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MAST1_MOUSE
NC score	0.029722 (rank : 316)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	333	Target Neighborhood Hits	1123	Shared Neighborhood Hits	133
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

DAB2_MOUSE
NC score	0.029386 (rank : 317)	θ value	1.81305 (rank : 200)
Query Neighborhood Hits	333	Target Neighborhood Hits	163	Shared Neighborhood Hits	13
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

MAST2_HUMAN
NC score	0.029312 (rank : 318)	θ value	5.27518 (rank : 280)
Query Neighborhood Hits	333	Target Neighborhood Hits	1189	Shared Neighborhood Hits	124
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

NCOR1_MOUSE
NC score	0.029001 (rank : 319)	θ value	1.38821 (rank : 190)
Query Neighborhood Hits	333	Target Neighborhood Hits	521	Shared Neighborhood Hits	41
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

MAST1_HUMAN
NC score	0.028866 (rank : 320)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	333	Target Neighborhood Hits	1146	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

RECQ5_HUMAN
NC score	0.028856 (rank : 321)	θ value	0.163984 (rank : 139)
Query Neighborhood Hits	333	Target Neighborhood Hits	390	Shared Neighborhood Hits	40
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

MAST2_MOUSE
NC score	0.027802 (rank : 322)	θ value	6.88961 (rank : 302)
Query Neighborhood Hits	333	Target Neighborhood Hits	1110	Shared Neighborhood Hits	119
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MTMR7_MOUSE
NC score	0.027274 (rank : 323)	θ value	0.0330416 (rank : 111)
Query Neighborhood Hits	333	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

CE016_HUMAN
NC score	0.027006 (rank : 324)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	333	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

ZIMP7_MOUSE
NC score	0.026107 (rank : 325)	θ value	6.88961 (rank : 311)
Query Neighborhood Hits	333	Target Neighborhood Hits	566	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

MINT_MOUSE
NC score	0.025814 (rank : 326)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	333	Target Neighborhood Hits	1514	Shared Neighborhood Hits	78
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

HRBL_HUMAN
NC score	0.025530 (rank : 327)	θ value	0.47712 (rank : 155)
Query Neighborhood Hits	333	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

AP3B1_MOUSE
NC score	0.025180 (rank : 328)	θ value	0.21417 (rank : 141)
Query Neighborhood Hits	333	Target Neighborhood Hits	302	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

MKL1_MOUSE
NC score	0.025167 (rank : 329)	θ value	4.03905 (rank : 253)
Query Neighborhood Hits	333	Target Neighborhood Hits	667	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

HTRA2_MOUSE
NC score	0.024669 (rank : 330)	θ value	5.27518 (rank : 277)
Query Neighborhood Hits	333	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

K0141_HUMAN
NC score	0.024463 (rank : 331)	θ value	1.06291 (rank : 178)
Query Neighborhood Hits	333	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q14154, Q969R4, Q96EU9	Gene names	KIAA0141
Domain Architecture
Description	Protein KIAA0141.

DTX1_MOUSE
NC score	0.023875 (rank : 332)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	333	Target Neighborhood Hits	99	Shared Neighborhood Hits	19
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

ATX2_HUMAN
NC score	0.023004 (rank : 333)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	333	Target Neighborhood Hits	375	Shared Neighborhood Hits	33
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

LBXCO_MOUSE
NC score	0.022369 (rank : 334)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	333	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

ZN687_HUMAN
NC score	0.022332 (rank : 335)	θ value	0.00298849 (rank : 86)
Query Neighborhood Hits	333	Target Neighborhood Hits	1244	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ALO17_HUMAN
NC score	0.021822 (rank : 336)	θ value	4.03905 (rank : 245)
Query Neighborhood Hits	333	Target Neighborhood Hits	317	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

NCOR1_HUMAN
NC score	0.021563 (rank : 337)	θ value	5.27518 (rank : 281)
Query Neighborhood Hits	333	Target Neighborhood Hits	577	Shared Neighborhood Hits	33
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

MAP1A_HUMAN
NC score	0.021284 (rank : 338)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	333	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

ATRX_MOUSE
NC score	0.021270 (rank : 339)	θ value	2.36792 (rank : 211)
Query Neighborhood Hits	333	Target Neighborhood Hits	682	Shared Neighborhood Hits	36
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

APC_HUMAN
NC score	0.020518 (rank : 340)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	333	Target Neighborhood Hits	603	Shared Neighborhood Hits	36
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ATRX_HUMAN
NC score	0.019999 (rank : 341)	θ value	0.47712 (rank : 154)
Query Neighborhood Hits	333	Target Neighborhood Hits	842	Shared Neighborhood Hits	30
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

MTMR7_HUMAN
NC score	0.019966 (rank : 342)	θ value	1.81305 (rank : 205)
Query Neighborhood Hits	333	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

CJ006_HUMAN
NC score	0.019576 (rank : 343)	θ value	2.36792 (rank : 214)
Query Neighborhood Hits	333	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IX21, Q5W0L8, Q9NPE8	Gene names	C10orf6
Domain Architecture	No domain graphic available
Description	Protein C10orf6.

MLL3_HUMAN
NC score	0.019263 (rank : 344)	θ value	8.99809 (rank : 325)
Query Neighborhood Hits	333	Target Neighborhood Hits	1644	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

KI67_HUMAN
NC score	0.018623 (rank : 345)	θ value	8.99809 (rank : 324)
Query Neighborhood Hits	333	Target Neighborhood Hits	581	Shared Neighborhood Hits	39
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

HRX_HUMAN
NC score	0.018416 (rank : 346)	θ value	8.99809 (rank : 322)
Query Neighborhood Hits	333	Target Neighborhood Hits	825	Shared Neighborhood Hits	53
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

AP3B1_HUMAN
NC score	0.018183 (rank : 347)	θ value	4.03905 (rank : 246)
Query Neighborhood Hits	333	Target Neighborhood Hits	283	Shared Neighborhood Hits	16
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ZN750_MOUSE
NC score	0.017802 (rank : 348)	θ value	5.27518 (rank : 284)
Query Neighborhood Hits	333	Target Neighborhood Hits	346	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

BTBDA_MOUSE
NC score	0.017489 (rank : 349)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	333	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X66	Gene names	Btbd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

ITCH_MOUSE
NC score	0.017182 (rank : 350)	θ value	0.813845 (rank : 174)
Query Neighborhood Hits	333	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

DTX1_HUMAN
NC score	0.016513 (rank : 351)	θ value	5.27518 (rank : 276)
Query Neighborhood Hits	333	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

TLN1_HUMAN
NC score	0.016346 (rank : 352)	θ value	4.03905 (rank : 260)
Query Neighborhood Hits	333	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

BTBDA_HUMAN
NC score	0.016298 (rank : 353)	θ value	6.88961 (rank : 290)
Query Neighborhood Hits	333	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSF8, Q86WG1	Gene names	BTBD10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

JADE2_MOUSE
NC score	0.015497 (rank : 354)	θ value	6.88961 (rank : 300)
Query Neighborhood Hits	333	Target Neighborhood Hits	560	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

TLN1_MOUSE
NC score	0.015346 (rank : 355)	θ value	6.88961 (rank : 308)
Query Neighborhood Hits	333	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

MY18B_HUMAN
NC score	0.014157 (rank : 356)	θ value	6.88961 (rank : 303)
Query Neighborhood Hits	333	Target Neighborhood Hits	1299	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

ZC3H6_MOUSE
NC score	0.014127 (rank : 357)	θ value	6.88961 (rank : 310)
Query Neighborhood Hits	333	Target Neighborhood Hits	239	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

MAML2_HUMAN
NC score	0.013892 (rank : 358)	θ value	5.27518 (rank : 279)
Query Neighborhood Hits	333	Target Neighborhood Hits	360	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

AFF2_HUMAN
NC score	0.013392 (rank : 359)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	333	Target Neighborhood Hits	218	Shared Neighborhood Hits	23
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

AKAP1_MOUSE
NC score	0.013037 (rank : 360)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	333	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

DOK2_MOUSE
NC score	0.012925 (rank : 361)	θ value	6.88961 (rank : 297)
Query Neighborhood Hits	333	Target Neighborhood Hits	244	Shared Neighborhood Hits	28
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

RRP44_HUMAN
NC score	0.012730 (rank : 362)	θ value	6.88961 (rank : 305)
Query Neighborhood Hits	333	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

NMDE4_MOUSE
NC score	0.012618 (rank : 363)	θ value	1.81305 (rank : 206)
Query Neighborhood Hits	333	Target Neighborhood Hits	158	Shared Neighborhood Hits	18
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

MYRIP_MOUSE
NC score	0.012613 (rank : 364)	θ value	6.88961 (rank : 304)
Query Neighborhood Hits	333	Target Neighborhood Hits	207	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

CCNL1_HUMAN
NC score	0.012139 (rank : 365)	θ value	2.36792 (rank : 212)
Query Neighborhood Hits	333	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

THOC2_HUMAN
NC score	0.011828 (rank : 366)	θ value	6.88961 (rank : 307)
Query Neighborhood Hits	333	Target Neighborhood Hits	337	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

SPRL1_MOUSE
NC score	0.011683 (rank : 367)	θ value	4.03905 (rank : 258)
Query Neighborhood Hits	333	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CCD96_HUMAN
NC score	0.011159 (rank : 368)	θ value	5.27518 (rank : 269)
Query Neighborhood Hits	333	Target Neighborhood Hits	595	Shared Neighborhood Hits	26
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

ERCC6_HUMAN
NC score	0.010778 (rank : 369)	θ value	1.81305 (rank : 201)
Query Neighborhood Hits	333	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

UBP34_MOUSE
NC score	0.010304 (rank : 370)	θ value	4.03905 (rank : 263)
Query Neighborhood Hits	333	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.010114 (rank : 371)	θ value	4.03905 (rank : 262)
Query Neighborhood Hits	333	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

CUTL2_HUMAN
NC score	0.009547 (rank : 372)	θ value	6.88961 (rank : 295)
Query Neighborhood Hits	333	Target Neighborhood Hits	906	Shared Neighborhood Hits	37
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

HAP1_MOUSE
NC score	0.009529 (rank : 373)	θ value	6.88961 (rank : 298)
Query Neighborhood Hits	333	Target Neighborhood Hits	388	Shared Neighborhood Hits	13
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

CIR_MOUSE
NC score	0.009440 (rank : 374)	θ value	6.88961 (rank : 291)
Query Neighborhood Hits	333	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

TTC16_HUMAN
NC score	0.008786 (rank : 375)	θ value	6.88961 (rank : 309)
Query Neighborhood Hits	333	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

DHX37_HUMAN
NC score	0.008700 (rank : 376)	θ value	5.27518 (rank : 275)
Query Neighborhood Hits	333	Target Neighborhood Hits	133	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

WNK2_HUMAN
NC score	0.007953 (rank : 377)	θ value	4.03905 (rank : 264)
Query Neighborhood Hits	333	Target Neighborhood Hits	1407	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

PARC_HUMAN
NC score	0.007697 (rank : 378)	θ value	4.03905 (rank : 256)
Query Neighborhood Hits	333	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

ZN409_HUMAN
NC score	0.007546 (rank : 379)	θ value	8.99809 (rank : 333)
Query Neighborhood Hits	333	Target Neighborhood Hits	842	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

ARBK1_HUMAN
NC score	0.007005 (rank : 380)	θ value	3.0926 (rank : 226)
Query Neighborhood Hits	333	Target Neighborhood Hits	859	Shared Neighborhood Hits	26
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

IRK9_HUMAN
NC score	0.006839 (rank : 381)	θ value	0.813845 (rank : 173)
Query Neighborhood Hits	333	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q92806, Q5JW75	Gene names	KCNJ9, GIRK3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

CSPG3_MOUSE
NC score	0.006584 (rank : 382)	θ value	1.06291 (rank : 177)
Query Neighborhood Hits	333	Target Neighborhood Hits	657	Shared Neighborhood Hits	25
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LIPB2_HUMAN
NC score	0.006462 (rank : 383)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	333	Target Neighborhood Hits	599	Shared Neighborhood Hits	18
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

TLX1_MOUSE
NC score	0.006365 (rank : 384)	θ value	0.47712 (rank : 160)
Query Neighborhood Hits	333	Target Neighborhood Hits	347	Shared Neighborhood Hits	16
SwissProt Accessions	P43345	Gene names	Tlx1, Hox11, Tlx-1
Domain Architecture
Description	T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Homeobox TLX-1).

ING1_HUMAN
NC score	0.006243 (rank : 385)	θ value	6.88961 (rank : 299)
Query Neighborhood Hits	333	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

DJBP_HUMAN
NC score	0.005571 (rank : 386)	θ value	8.99809 (rank : 315)
Query Neighborhood Hits	333	Target Neighborhood Hits	156	Shared Neighborhood Hits	3
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

SDK1_HUMAN
NC score	0.005491 (rank : 387)	θ value	0.21417 (rank : 144)
Query Neighborhood Hits	333	Target Neighborhood Hits	511	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ARBK1_MOUSE
NC score	0.004685 (rank : 388)	θ value	0.62314 (rank : 162)
Query Neighborhood Hits	333	Target Neighborhood Hits	849	Shared Neighborhood Hits	22
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

PAX5_MOUSE
NC score	0.004549 (rank : 389)	θ value	5.27518 (rank : 282)
Query Neighborhood Hits	333	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

OTOF_MOUSE
NC score	0.004488 (rank : 390)	θ value	8.99809 (rank : 328)
Query Neighborhood Hits	333	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

SLAP1_MOUSE
NC score	0.003278 (rank : 391)	θ value	5.27518 (rank : 283)
Query Neighborhood Hits	333	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q60898, Q8C9Q8, Q8CAT0, Q8CBE9, Q8QZX8	Gene names	Sla, Slap, Slap1
Domain Architecture
Description	SRC-like-adapter (Src-like-adapter protein 1) (mSLAP).

DJC16_MOUSE
NC score	0.003039 (rank : 392)	θ value	6.88961 (rank : 296)
Query Neighborhood Hits	333	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TN4, Q811G1, Q8BHI2	Gene names	Dnajc16, Kiaa0962
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 16 precursor.

LMNB1_MOUSE
NC score	0.002764 (rank : 393)	θ value	4.03905 (rank : 252)
Query Neighborhood Hits	333	Target Neighborhood Hits	719	Shared Neighborhood Hits	18
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

LMNB1_HUMAN
NC score	0.002747 (rank : 394)	θ value	4.03905 (rank : 251)
Query Neighborhood Hits	333	Target Neighborhood Hits	714	Shared Neighborhood Hits	20
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

SCN5A_HUMAN
NC score	0.000963 (rank : 395)	θ value	8.99809 (rank : 331)
Query Neighborhood Hits	333	Target Neighborhood Hits	145	Shared Neighborhood Hits	9
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CD2L7_HUMAN
NC score	0.000678 (rank : 396)	θ value	2.36792 (rank : 213)
Query Neighborhood Hits	333	Target Neighborhood Hits	1275	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

FOXK1_MOUSE
NC score	0.000549 (rank : 397)	θ value	8.99809 (rank : 320)
Query Neighborhood Hits	333	Target Neighborhood Hits	215	Shared Neighborhood Hits	10
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

GP152_MOUSE
NC score	0.000327 (rank : 398)	θ value	8.99809 (rank : 321)
Query Neighborhood Hits	333	Target Neighborhood Hits	607	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

TRAIP_MOUSE
NC score	0.000281 (rank : 399)	θ value	8.99809 (rank : 332)
Query Neighborhood Hits	333	Target Neighborhood Hits	745	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

OBSCN_HUMAN
NC score	-0.000921 (rank : 400)	θ value	8.99809 (rank : 327)
Query Neighborhood Hits	333	Target Neighborhood Hits	1931	Shared Neighborhood Hits	73
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

HXD9_MOUSE
NC score	-0.001400 (rank : 401)	θ value	8.99809 (rank : 323)
Query Neighborhood Hits	333	Target Neighborhood Hits	359	Shared Neighborhood Hits	9
SwissProt Accessions	P28357, Q3UYS2	Gene names	Hoxd9, Hox-4.4, Hoxd-9
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4.4) (Hox-5.2).

KSR1_HUMAN
NC score	-0.003862 (rank : 402)	θ value	4.03905 (rank : 250)
Query Neighborhood Hits	333	Target Neighborhood Hits	867	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

ZN167_HUMAN
NC score	-0.004864 (rank : 403)	θ value	0.0330416 (rank : 113)
Query Neighborhood Hits	333	Target Neighborhood Hits	784	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0L1, Q6WL09, Q96FQ2	Gene names	ZNF167, ZNF448, ZNF64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 167 (Zinc finger protein 64) (Zinc finger protein 448) (ZFP).

ZN213_HUMAN
NC score	-0.006378 (rank : 404)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	333	Target Neighborhood Hits	755	Shared Neighborhood Hits	5
SwissProt Accessions	O14771, Q96IS1	Gene names	ZNF213
Domain Architecture
Description	Zinc finger protein 213 (Putative transcription factor CR53).

ADA1D_HUMAN
NC score	-0.008340 (rank : 405)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	333	Target Neighborhood Hits	937	Shared Neighborhood Hits	12
SwissProt Accessions	P25100, Q9NPY0	Gene names	ADRA1D, ADRA1A
Domain Architecture
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D- adrenoreceptor) (Alpha-1A adrenergic receptor) (Alpha adrenergic receptor 1a).