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Network neighborhood for query Sequence : UBP34_MOUSE

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UBP34_MOUSE
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP34_HUMAN
θ value	0 (rank : 1)	NC score	0.995161 (rank : 2)
Query Neighborhood Hits	189	Target Neighborhood Hits	210	Shared Neighborhood Hits	155
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	189	Target Neighborhood Hits	189	Shared Neighborhood Hits	189
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

USP9X_HUMAN
θ value	5.34618e-69 (rank : 3)	NC score	0.810938 (rank : 5)
Query Neighborhood Hits	189	Target Neighborhood Hits	161	Shared Neighborhood Hits	71
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	1.2325e-65 (rank : 4)	NC score	0.806973 (rank : 6)
Query Neighborhood Hits	189	Target Neighborhood Hits	171	Shared Neighborhood Hits	71
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9Y_HUMAN
θ value	6.11685e-65 (rank : 5)	NC score	0.813590 (rank : 4)
Query Neighborhood Hits	189	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP24_HUMAN
θ value	1.77973e-64 (rank : 6)	NC score	0.853539 (rank : 3)
Query Neighborhood Hits	189	Target Neighborhood Hits	96	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP48_HUMAN
θ value	8.61488e-35 (rank : 7)	NC score	0.799697 (rank : 9)
Query Neighborhood Hits	189	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
θ value	8.61488e-35 (rank : 8)	NC score	0.797785 (rank : 10)
Query Neighborhood Hits	189	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP47_MOUSE
θ value	4.89182e-30 (rank : 9)	NC score	0.773755 (rank : 11)
Query Neighborhood Hits	189	Target Neighborhood Hits	135	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
θ value	1.2049e-28 (rank : 10)	NC score	0.771126 (rank : 12)
Query Neighborhood Hits	189	Target Neighborhood Hits	149	Shared Neighborhood Hits	76
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP7_HUMAN
θ value	1.2049e-28 (rank : 11)	NC score	0.804794 (rank : 7)
Query Neighborhood Hits	189	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP40_HUMAN
θ value	7.80994e-28 (rank : 12)	NC score	0.804113 (rank : 8)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP46_HUMAN
θ value	2.43343e-21 (rank : 13)	NC score	0.744071 (rank : 14)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	2.43343e-21 (rank : 14)	NC score	0.744071 (rank : 15)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP12_HUMAN
θ value	2.69047e-20 (rank : 15)	NC score	0.740282 (rank : 16)
Query Neighborhood Hits	189	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP36_HUMAN
θ value	3.88503e-19 (rank : 16)	NC score	0.708691 (rank : 18)
Query Neighborhood Hits	189	Target Neighborhood Hits	232	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP2_MOUSE
θ value	2.13179e-17 (rank : 17)	NC score	0.667330 (rank : 26)
Query Neighborhood Hits	189	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP18_HUMAN
θ value	4.74913e-17 (rank : 18)	NC score	0.754726 (rank : 13)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP42_HUMAN
θ value	4.74913e-17 (rank : 19)	NC score	0.672922 (rank : 24)
Query Neighborhood Hits	189	Target Neighborhood Hits	445	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP2_HUMAN
θ value	1.058e-16 (rank : 20)	NC score	0.665920 (rank : 27)
Query Neighborhood Hits	189	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP51_HUMAN
θ value	6.85773e-16 (rank : 21)	NC score	0.680504 (rank : 23)
Query Neighborhood Hits	189	Target Neighborhood Hits	162	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP22_HUMAN
θ value	8.95645e-16 (rank : 22)	NC score	0.686720 (rank : 21)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP50_MOUSE
θ value	8.95645e-16 (rank : 23)	NC score	0.671014 (rank : 25)
Query Neighborhood Hits	189	Target Neighborhood Hits	80	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP22_MOUSE
θ value	5.8054e-15 (rank : 24)	NC score	0.683780 (rank : 22)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP18_MOUSE
θ value	7.58209e-15 (rank : 25)	NC score	0.731194 (rank : 17)
Query Neighborhood Hits	189	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UB17L_HUMAN
θ value	3.18553e-13 (rank : 26)	NC score	0.695229 (rank : 20)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP33_HUMAN
θ value	4.16044e-13 (rank : 27)	NC score	0.659749 (rank : 29)
Query Neighborhood Hits	189	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP8_MOUSE
θ value	7.09661e-13 (rank : 28)	NC score	0.643382 (rank : 32)
Query Neighborhood Hits	189	Target Neighborhood Hits	362	Shared Neighborhood Hits	87
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP20_HUMAN
θ value	2.0648e-12 (rank : 29)	NC score	0.662930 (rank : 28)
Query Neighborhood Hits	189	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP8_HUMAN
θ value	2.0648e-12 (rank : 30)	NC score	0.610369 (rank : 40)
Query Neighborhood Hits	189	Target Neighborhood Hits	751	Shared Neighborhood Hits	97
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP3_HUMAN
θ value	4.59992e-12 (rank : 31)	NC score	0.657671 (rank : 30)
Query Neighborhood Hits	189	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBPW_MOUSE
θ value	6.00763e-12 (rank : 32)	NC score	0.697604 (rank : 19)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP3_MOUSE
θ value	1.33837e-11 (rank : 33)	NC score	0.657521 (rank : 31)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP35_HUMAN
θ value	2.98157e-11 (rank : 34)	NC score	0.625497 (rank : 39)
Query Neighborhood Hits	189	Target Neighborhood Hits	223	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP28_MOUSE
θ value	6.64225e-11 (rank : 35)	NC score	0.507887 (rank : 56)
Query Neighborhood Hits	189	Target Neighborhood Hits	178	Shared Neighborhood Hits	71
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP25_MOUSE
θ value	1.47974e-10 (rank : 36)	NC score	0.496003 (rank : 58)
Query Neighborhood Hits	189	Target Neighborhood Hits	116	Shared Neighborhood Hits	69
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP21_MOUSE
θ value	1.9326e-10 (rank : 37)	NC score	0.638605 (rank : 34)
Query Neighborhood Hits	189	Target Neighborhood Hits	101	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP21_HUMAN
θ value	4.30538e-10 (rank : 38)	NC score	0.637307 (rank : 35)
Query Neighborhood Hits	189	Target Neighborhood Hits	95	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP25_HUMAN
θ value	4.30538e-10 (rank : 39)	NC score	0.491152 (rank : 60)
Query Neighborhood Hits	189	Target Neighborhood Hits	124	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP28_HUMAN
θ value	5.62301e-10 (rank : 40)	NC score	0.507163 (rank : 57)
Query Neighborhood Hits	189	Target Neighborhood Hits	117	Shared Neighborhood Hits	73
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP4_MOUSE
θ value	5.62301e-10 (rank : 41)	NC score	0.554672 (rank : 50)
Query Neighborhood Hits	189	Target Neighborhood Hits	90	Shared Neighborhood Hits	70
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP50_HUMAN
θ value	9.59137e-10 (rank : 42)	NC score	0.639522 (rank : 33)
Query Neighborhood Hits	189	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP4_HUMAN
θ value	1.63604e-09 (rank : 43)	NC score	0.553601 (rank : 51)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP49_HUMAN
θ value	2.13673e-09 (rank : 44)	NC score	0.627599 (rank : 37)
Query Neighborhood Hits	189	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_MOUSE
θ value	2.79066e-09 (rank : 45)	NC score	0.626700 (rank : 38)
Query Neighborhood Hits	189	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP11_HUMAN
θ value	3.64472e-09 (rank : 46)	NC score	0.562726 (rank : 45)
Query Neighborhood Hits	189	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP44_HUMAN
θ value	8.11959e-09 (rank : 47)	NC score	0.628150 (rank : 36)
Query Neighborhood Hits	189	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP38_HUMAN
θ value	2.36244e-08 (rank : 48)	NC score	0.581431 (rank : 41)
Query Neighborhood Hits	189	Target Neighborhood Hits	97	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP15_HUMAN
θ value	8.97725e-08 (rank : 49)	NC score	0.556233 (rank : 48)
Query Neighborhood Hits	189	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	1.17247e-07 (rank : 50)	NC score	0.555629 (rank : 49)
Query Neighborhood Hits	189	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP31_HUMAN
θ value	1.53129e-07 (rank : 51)	NC score	0.559127 (rank : 46)
Query Neighborhood Hits	189	Target Neighborhood Hits	293	Shared Neighborhood Hits	78
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP37_HUMAN
θ value	2.88788e-06 (rank : 52)	NC score	0.495691 (rank : 59)
Query Neighborhood Hits	189	Target Neighborhood Hits	208	Shared Neighborhood Hits	80
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP38_MOUSE
θ value	6.43352e-06 (rank : 53)	NC score	0.566576 (rank : 44)
Query Neighborhood Hits	189	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP14_HUMAN
θ value	8.40245e-06 (rank : 54)	NC score	0.556619 (rank : 47)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
θ value	1.09739e-05 (rank : 55)	NC score	0.529442 (rank : 54)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP43_HUMAN
θ value	1.87187e-05 (rank : 56)	NC score	0.541006 (rank : 53)
Query Neighborhood Hits	189	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP1_HUMAN
θ value	4.1701e-05 (rank : 57)	NC score	0.577278 (rank : 42)
Query Neighborhood Hits	189	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP43_MOUSE
θ value	0.000121331 (rank : 58)	NC score	0.541165 (rank : 52)
Query Neighborhood Hits	189	Target Neighborhood Hits	130	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

DSPP_HUMAN
θ value	0.000786445 (rank : 59)	NC score	0.096718 (rank : 76)
Query Neighborhood Hits	189	Target Neighborhood Hits	645	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DMP1_HUMAN
θ value	0.00390308 (rank : 60)	NC score	0.111280 (rank : 74)
Query Neighborhood Hits	189	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

MYST4_HUMAN
θ value	0.00390308 (rank : 61)	NC score	0.049676 (rank : 89)
Query Neighborhood Hits	189	Target Neighborhood Hits	671	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

UBP16_HUMAN
θ value	0.00665767 (rank : 62)	NC score	0.577190 (rank : 43)
Query Neighborhood Hits	189	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP30_HUMAN
θ value	0.0113563 (rank : 63)	NC score	0.513909 (rank : 55)
Query Neighborhood Hits	189	Target Neighborhood Hits	94	Shared Neighborhood Hits	67
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

DSPP_MOUSE
θ value	0.0148317 (rank : 64)	NC score	0.099682 (rank : 75)
Query Neighborhood Hits	189	Target Neighborhood Hits	491	Shared Neighborhood Hits	38
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PMS2_HUMAN
θ value	0.0193708 (rank : 65)	NC score	0.066808 (rank : 78)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

UBP13_HUMAN
θ value	0.0252991 (rank : 66)	NC score	0.371206 (rank : 70)
Query Neighborhood Hits	189	Target Neighborhood Hits	99	Shared Neighborhood Hits	70
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP32_HUMAN
θ value	0.0252991 (rank : 67)	NC score	0.435386 (rank : 63)
Query Neighborhood Hits	189	Target Neighborhood Hits	170	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

NALP5_MOUSE
θ value	0.0431538 (rank : 68)	NC score	0.034630 (rank : 103)
Query Neighborhood Hits	189	Target Neighborhood Hits	560	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

UBP29_HUMAN
θ value	0.0563607 (rank : 69)	NC score	0.402126 (rank : 65)
Query Neighborhood Hits	189	Target Neighborhood Hits	94	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP6_HUMAN
θ value	0.0563607 (rank : 70)	NC score	0.407430 (rank : 64)
Query Neighborhood Hits	189	Target Neighborhood Hits	188	Shared Neighborhood Hits	70
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

IWS1_HUMAN
θ value	0.0736092 (rank : 71)	NC score	0.063231 (rank : 83)
Query Neighborhood Hits	189	Target Neighborhood Hits	1241	Shared Neighborhood Hits	58
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

UBP5_HUMAN
θ value	0.0736092 (rank : 72)	NC score	0.376578 (rank : 69)
Query Neighborhood Hits	189	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	0.0736092 (rank : 73)	NC score	0.377448 (rank : 68)
Query Neighborhood Hits	189	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

DMP1_MOUSE
θ value	0.125558 (rank : 74)	NC score	0.079409 (rank : 77)
Query Neighborhood Hits	189	Target Neighborhood Hits	498	Shared Neighborhood Hits	40
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

RERE_MOUSE
θ value	0.125558 (rank : 75)	NC score	0.038863 (rank : 96)
Query Neighborhood Hits	189	Target Neighborhood Hits	785	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

IWS1_MOUSE
θ value	0.163984 (rank : 76)	NC score	0.063739 (rank : 82)
Query Neighborhood Hits	189	Target Neighborhood Hits	1258	Shared Neighborhood Hits	65
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

FILA_HUMAN
θ value	0.21417 (rank : 77)	NC score	0.054433 (rank : 86)
Query Neighborhood Hits	189	Target Neighborhood Hits	685	Shared Neighborhood Hits	40
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

CD2L2_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.006597 (rank : 174)
Query Neighborhood Hits	189	Target Neighborhood Hits	1439	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

LEO1_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.065385 (rank : 79)
Query Neighborhood Hits	189	Target Neighborhood Hits	946	Shared Neighborhood Hits	59
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MYT1L_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.035923 (rank : 99)
Query Neighborhood Hits	189	Target Neighborhood Hits	471	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

MYT1L_MOUSE
θ value	0.279714 (rank : 81)	NC score	0.034902 (rank : 102)
Query Neighborhood Hits	189	Target Neighborhood Hits	461	Shared Neighborhood Hits	24
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

RNF34_MOUSE
θ value	0.279714 (rank : 82)	NC score	0.050388 (rank : 88)
Query Neighborhood Hits	189	Target Neighborhood Hits	160	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

UBP26_HUMAN
θ value	0.279714 (rank : 83)	NC score	0.369748 (rank : 71)
Query Neighborhood Hits	189	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

ATRX_MOUSE
θ value	0.365318 (rank : 84)	NC score	0.039824 (rank : 95)
Query Neighborhood Hits	189	Target Neighborhood Hits	682	Shared Neighborhood Hits	47
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

NPHP1_HUMAN
θ value	0.365318 (rank : 85)	NC score	0.035663 (rank : 100)
Query Neighborhood Hits	189	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

TOM1_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.038774 (rank : 97)
Query Neighborhood Hits	189	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

ZN447_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.006410 (rank : 175)
Query Neighborhood Hits	189	Target Neighborhood Hits	899	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

LRRF1_MOUSE
θ value	0.47712 (rank : 88)	NC score	0.052273 (rank : 87)
Query Neighborhood Hits	189	Target Neighborhood Hits	440	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

RSF1_HUMAN
θ value	0.47712 (rank : 89)	NC score	0.045730 (rank : 91)
Query Neighborhood Hits	189	Target Neighborhood Hits	539	Shared Neighborhood Hits	32
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

ZCHC7_HUMAN
θ value	0.47712 (rank : 90)	NC score	0.037422 (rank : 98)
Query Neighborhood Hits	189	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

K1718_MOUSE
θ value	0.62314 (rank : 91)	NC score	0.025965 (rank : 122)
Query Neighborhood Hits	189	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

LMNB1_MOUSE
θ value	0.62314 (rank : 92)	NC score	0.014755 (rank : 142)
Query Neighborhood Hits	189	Target Neighborhood Hits	719	Shared Neighborhood Hits	20
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

MYST3_MOUSE
θ value	0.62314 (rank : 93)	NC score	0.043787 (rank : 93)
Query Neighborhood Hits	189	Target Neighborhood Hits	688	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

ARI5B_HUMAN
θ value	0.813845 (rank : 94)	NC score	0.032318 (rank : 106)
Query Neighborhood Hits	189	Target Neighborhood Hits	328	Shared Neighborhood Hits	25
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

LEO1_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.064541 (rank : 80)
Query Neighborhood Hits	189	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MACF4_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.010420 (rank : 159)
Query Neighborhood Hits	189	Target Neighborhood Hits	1321	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MYST3_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.044621 (rank : 92)
Query Neighborhood Hits	189	Target Neighborhood Hits	772	Shared Neighborhood Hits	40
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

LMNB2_MOUSE
θ value	1.06291 (rank : 98)	NC score	0.013415 (rank : 147)
Query Neighborhood Hits	189	Target Neighborhood Hits	674	Shared Neighborhood Hits	16
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

WAPL_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.039929 (rank : 94)
Query Neighborhood Hits	189	Target Neighborhood Hits	122	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

TOM1_MOUSE
θ value	1.38821 (rank : 100)	NC score	0.031005 (rank : 109)
Query Neighborhood Hits	189	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

ANC5_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.031396 (rank : 108)
Query Neighborhood Hits	189	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJX4, Q8N4H7, Q9BQD4	Gene names	ANAPC5, APC5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

ARY2_MOUSE
θ value	1.81305 (rank : 102)	NC score	0.026256 (rank : 120)
Query Neighborhood Hits	189	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P50295	Gene names	Nat2, Aac2
Domain Architecture
Description	Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2).

CD2L1_MOUSE
θ value	1.81305 (rank : 103)	NC score	0.002090 (rank : 186)
Query Neighborhood Hits	189	Target Neighborhood Hits	1463	Shared Neighborhood Hits	45
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CJ012_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.035305 (rank : 101)
Query Neighborhood Hits	189	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

GCP5_HUMAN
θ value	1.81305 (rank : 105)	NC score	0.029107 (rank : 112)
Query Neighborhood Hits	189	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RT8, Q96PY8	Gene names	TUBGCP5, GCP5, KIAA1899
Domain Architecture
Description	Gamma-tubulin complex component 5 (GCP-5).

LMNB1_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.012552 (rank : 150)
Query Neighborhood Hits	189	Target Neighborhood Hits	714	Shared Neighborhood Hits	21
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

MPP8_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.021377 (rank : 130)
Query Neighborhood Hits	189	Target Neighborhood Hits	948	Shared Neighborhood Hits	43
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MSH6_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.018867 (rank : 137)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

RFFL_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.031885 (rank : 107)
Query Neighborhood Hits	189	Target Neighborhood Hits	175	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

UBR1_MOUSE
θ value	1.81305 (rank : 110)	NC score	0.016558 (rank : 138)
Query Neighborhood Hits	189	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

CCD55_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.034232 (rank : 104)
Query Neighborhood Hits	189	Target Neighborhood Hits	519	Shared Neighborhood Hits	35
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

LMNB2_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.011115 (rank : 157)
Query Neighborhood Hits	189	Target Neighborhood Hits	723	Shared Neighborhood Hits	17
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

MK67I_MOUSE
θ value	2.36792 (rank : 113)	NC score	0.014134 (rank : 143)
Query Neighborhood Hits	189	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VE6, Q8BMV9, Q8BVL4	Gene names	Mki67ip, Nifk
Domain Architecture	No domain graphic available
Description	MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar protein interacting with the FHA domain of pKI-67) (mNIFK).

RERE_HUMAN
θ value	2.36792 (rank : 114)	NC score	0.030920 (rank : 110)
Query Neighborhood Hits	189	Target Neighborhood Hits	779	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SMRC1_MOUSE
θ value	2.36792 (rank : 115)	NC score	0.026645 (rank : 117)
Query Neighborhood Hits	189	Target Neighborhood Hits	459	Shared Neighborhood Hits	30
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

T2FA_HUMAN
θ value	2.36792 (rank : 116)	NC score	0.055185 (rank : 85)
Query Neighborhood Hits	189	Target Neighborhood Hits	228	Shared Neighborhood Hits	23
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TCOF_HUMAN
θ value	2.36792 (rank : 117)	NC score	0.020326 (rank : 133)
Query Neighborhood Hits	189	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CI082_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.028670 (rank : 113)
Query Neighborhood Hits	189	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

ERCC5_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.024901 (rank : 124)
Query Neighborhood Hits	189	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

K0020_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.023742 (rank : 126)
Query Neighborhood Hits	189	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q15397, Q547G7, Q5SZY9, Q6IB47, Q96B27, Q96L78, Q96L79, Q96L80	Gene names	KIAA0020, XTP5
Domain Architecture	No domain graphic available
Description	Protein KIAA0020 (HBV X-transactivated gene 5 protein) (Minor histocompatibility antigen HA-8) (HLA-HA8).

RPTN_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.030266 (rank : 111)
Query Neighborhood Hits	189	Target Neighborhood Hits	406	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

TP4AP_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.026639 (rank : 118)
Query Neighborhood Hits	189	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEL6, Q96H82, Q9BVB8, Q9H429, Q9UFS6	Gene names	TRPC4AP, C20orf188, TRRP4AP
Domain Architecture	No domain graphic available
Description	Trpc4-associated protein (Short transient receptor potential channel 4-associated protein) (Trp4-associated protein) (TAP1 protein) (TNF- receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS).

TP4AP_MOUSE
θ value	3.0926 (rank : 123)	NC score	0.026589 (rank : 119)
Query Neighborhood Hits	189	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLV2, Q920J6, Q99L03	Gene names	Trpc4ap, Trrp4ap
Domain Architecture	No domain graphic available
Description	Trpc4-associated protein (Trp4-associated protein) (Short transient receptor potential channel 4-associated protein) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS) (TAP1 protein) (Rabex-5/Rin2-interacting protein).

CLSPN_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.021238 (rank : 131)
Query Neighborhood Hits	189	Target Neighborhood Hits	433	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

NALP4_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.010619 (rank : 158)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NOS2_MOUSE
θ value	4.03905 (rank : 126)	NC score	0.012407 (rank : 151)
Query Neighborhood Hits	189	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

NUMA1_HUMAN
θ value	4.03905 (rank : 127)	NC score	0.007596 (rank : 171)
Query Neighborhood Hits	189	Target Neighborhood Hits	1523	Shared Neighborhood Hits	34
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

RGS12_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.010304 (rank : 161)
Query Neighborhood Hits	189	Target Neighborhood Hits	333	Shared Neighborhood Hits	10
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RRBP1_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.019369 (rank : 135)
Query Neighborhood Hits	189	Target Neighborhood Hits	1650	Shared Neighborhood Hits	57
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SYNE1_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.008233 (rank : 168)
Query Neighborhood Hits	189	Target Neighborhood Hits	1484	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ARY1_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.019003 (rank : 136)
Query Neighborhood Hits	189	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P18440, O15159, O15300	Gene names	NAT1, AAC1
Domain Architecture
Description	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Arylamine N-acetyltransferase, monomorphic) (MNAT) (N- acetyltransferase type 1) (NAT-1).

CENPE_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.006194 (rank : 177)
Query Neighborhood Hits	189	Target Neighborhood Hits	2060	Shared Neighborhood Hits	54
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

COHA1_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.007666 (rank : 170)
Query Neighborhood Hits	189	Target Neighborhood Hits	400	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CP007_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.025177 (rank : 123)
Query Neighborhood Hits	189	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

DCR1A_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.010119 (rank : 162)
Query Neighborhood Hits	189	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

FA44A_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.027240 (rank : 115)
Query Neighborhood Hits	189	Target Neighborhood Hits	280	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

HDAC6_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.047433 (rank : 90)
Query Neighborhood Hits	189	Target Neighborhood Hits	145	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

NF2L3_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.015736 (rank : 140)
Query Neighborhood Hits	189	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

PP2CG_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.027203 (rank : 116)
Query Neighborhood Hits	189	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

PTN13_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.007353 (rank : 172)
Query Neighborhood Hits	189	Target Neighborhood Hits	471	Shared Neighborhood Hits	18
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

RPTN_MOUSE
θ value	5.27518 (rank : 141)	NC score	0.026092 (rank : 121)
Query Neighborhood Hits	189	Target Neighborhood Hits	650	Shared Neighborhood Hits	34
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SNUT2_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.388015 (rank : 67)
Query Neighborhood Hits	189	Target Neighborhood Hits	79	Shared Neighborhood Hits	56
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	5.27518 (rank : 143)	NC score	0.398042 (rank : 66)
Query Neighborhood Hits	189	Target Neighborhood Hits	80	Shared Neighborhood Hits	57
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBR1_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.013754 (rank : 145)
Query Neighborhood Hits	189	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

ZNF12_HUMAN
θ value	5.27518 (rank : 145)	NC score	-0.004642 (rank : 193)
Query Neighborhood Hits	189	Target Neighborhood Hits	779	Shared Neighborhood Hits	5
SwissProt Accessions	P17014, Q9ULZ6	Gene names	ZNF12, GIOT3, KOX3, ZNF325
Domain Architecture	No domain graphic available
Description	Zinc finger protein 12 (Zinc finger protein KOX3) (Zinc finger protein 325) (Gonadotropin-inducible transcription repressor 3) (GIOT-3).

ABTAP_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.032335 (rank : 105)
Query Neighborhood Hits	189	Target Neighborhood Hits	381	Shared Neighborhood Hits	23
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

BASP_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.023100 (rank : 128)
Query Neighborhood Hits	189	Target Neighborhood Hits	260	Shared Neighborhood Hits	12
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CDKN3_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.028210 (rank : 114)
Query Neighborhood Hits	189	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

CENG2_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.001547 (rank : 188)
Query Neighborhood Hits	189	Target Neighborhood Hits	471	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CHD2_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.011735 (rank : 153)
Query Neighborhood Hits	189	Target Neighborhood Hits	360	Shared Neighborhood Hits	25
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

DHSB_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.023608 (rank : 127)
Query Neighborhood Hits	189	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P21912, Q9NQ12	Gene names	SDHB, SDH, SDH1
Domain Architecture	No domain graphic available
Description	Succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial precursor (EC 1.3.5.1) (Ip) (Iron-sulfur subunit of complex II).

DHSB_MOUSE
θ value	6.88961 (rank : 152)	NC score	0.023771 (rank : 125)
Query Neighborhood Hits	189	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQA3, Q3TF82, Q9DC91	Gene names	Sdhb
Domain Architecture	No domain graphic available
Description	Succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial precursor (EC 1.3.5.1) (Ip) (Iron-sulfur subunit of complex II).

EMIL3_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.006299 (rank : 176)
Query Neighborhood Hits	189	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

GBRA1_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.004077 (rank : 184)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	P14867, Q8N629	Gene names	GABRA1
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit alpha-1 precursor (GABA(A) receptor subunit alpha-1).

ISK5_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.011343 (rank : 155)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

JHD2C_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.010024 (rank : 164)
Query Neighborhood Hits	189	Target Neighborhood Hits	279	Shared Neighborhood Hits	19
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

K0460_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.013579 (rank : 146)
Query Neighborhood Hits	189	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

MA2A1_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.013007 (rank : 148)
Query Neighborhood Hits	189	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q16706, Q16767	Gene names	MAN2A1, MANA2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1).

MLL3_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.010306 (rank : 160)
Query Neighborhood Hits	189	Target Neighborhood Hits	1644	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

P52K_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.015411 (rank : 141)
Query Neighborhood Hits	189	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

PAR10_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.020270 (rank : 134)
Query Neighborhood Hits	189	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PDE4A_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.008082 (rank : 169)
Query Neighborhood Hits	189	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

PININ_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.020852 (rank : 132)
Query Neighborhood Hits	189	Target Neighborhood Hits	777	Shared Neighborhood Hits	43
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RYR3_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.006009 (rank : 178)
Query Neighborhood Hits	189	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

UBP29_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.364957 (rank : 72)
Query Neighborhood Hits	189	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

A16L1_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.004310 (rank : 182)
Query Neighborhood Hits	189	Target Neighborhood Hits	776	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

ACET_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.009982 (rank : 165)
Query Neighborhood Hits	189	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.009702 (rank : 166)
Query Neighborhood Hits	189	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

BAZ1A_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.016243 (rank : 139)
Query Neighborhood Hits	189	Target Neighborhood Hits	693	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CD2L1_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.002429 (rank : 185)
Query Neighborhood Hits	189	Target Neighborhood Hits	1467	Shared Neighborhood Hits	43
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CENG2_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.001212 (rank : 189)
Query Neighborhood Hits	189	Target Neighborhood Hits	463	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENPJ_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.012812 (rank : 149)
Query Neighborhood Hits	189	Target Neighborhood Hits	721	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CHIT1_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.006798 (rank : 173)
Query Neighborhood Hits	189	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

CTGE5_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.004582 (rank : 181)
Query Neighborhood Hits	189	Target Neighborhood Hits	928	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

HIPK3_HUMAN
θ value	8.99809 (rank : 175)	NC score	-0.002096 (rank : 190)
Query Neighborhood Hits	189	Target Neighborhood Hits	867	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

KI21A_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.008542 (rank : 167)
Query Neighborhood Hits	189	Target Neighborhood Hits	1317	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KKCC2_HUMAN
θ value	8.99809 (rank : 177)	NC score	-0.003739 (rank : 192)
Query Neighborhood Hits	189	Target Neighborhood Hits	852	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KKCC2_MOUSE
θ value	8.99809 (rank : 178)	NC score	-0.003738 (rank : 191)
Query Neighborhood Hits	189	Target Neighborhood Hits	855	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

LASS5_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.004085 (rank : 183)
Query Neighborhood Hits	189	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6K9, Q3UL17, Q80YB2, Q8BPH6, Q921T8, Q924Z3	Gene names	Lass5, Trh4
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 5 (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4).

MA2A1_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.011625 (rank : 154)
Query Neighborhood Hits	189	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

MKL1_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.005858 (rank : 179)
Query Neighborhood Hits	189	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MPP10_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.013891 (rank : 144)
Query Neighborhood Hits	189	Target Neighborhood Hits	306	Shared Neighborhood Hits	20
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

NCOR1_MOUSE
θ value	8.99809 (rank : 183)	NC score	0.010061 (rank : 163)
Query Neighborhood Hits	189	Target Neighborhood Hits	521	Shared Neighborhood Hits	29
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PROM1_MOUSE
θ value	8.99809 (rank : 184)	NC score	0.022150 (rank : 129)
Query Neighborhood Hits	189	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

RTN1_MOUSE
θ value	8.99809 (rank : 185)	NC score	0.012151 (rank : 152)
Query Neighborhood Hits	189	Target Neighborhood Hits	189	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

SEM6D_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.001570 (rank : 187)
Query Neighborhood Hits	189	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

TMC2_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.005159 (rank : 180)
Query Neighborhood Hits	189	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

ZAR1_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.011291 (rank : 156)
Query Neighborhood Hits	189	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZN642_HUMAN
θ value	8.99809 (rank : 189)	NC score	-0.005149 (rank : 194)
Query Neighborhood Hits	189	Target Neighborhood Hits	744	Shared Neighborhood Hits	5
SwissProt Accessions	Q49AA0, Q5SWM5, Q6ZWK8	Gene names	ZNF642
Domain Architecture	No domain graphic available
Description	Zinc finger protein 642.

BRAP_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.055869 (rank : 84)
Query Neighborhood Hits	189	Target Neighborhood Hits	560	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.063991 (rank : 81)
Query Neighborhood Hits	189	Target Neighborhood Hits	409	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

UBP10_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.442053 (rank : 61)
Query Neighborhood Hits	189	Target Neighborhood Hits	153	Shared Neighborhood Hits	68
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.441285 (rank : 62)
Query Neighborhood Hits	189	Target Neighborhood Hits	150	Shared Neighborhood Hits	71
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP26_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.294343 (rank : 73)
Query Neighborhood Hits	189	Target Neighborhood Hits	107	Shared Neighborhood Hits	67
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

Hits sorted by NC score

UBP34_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	189	Target Neighborhood Hits	189	Shared Neighborhood Hits	189
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.995161 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	189	Target Neighborhood Hits	210	Shared Neighborhood Hits	155
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP24_HUMAN
NC score	0.853539 (rank : 3)	θ value	1.77973e-64 (rank : 6)
Query Neighborhood Hits	189	Target Neighborhood Hits	96	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

USP9Y_HUMAN
NC score	0.813590 (rank : 4)	θ value	6.11685e-65 (rank : 5)
Query Neighborhood Hits	189	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

USP9X_HUMAN
NC score	0.810938 (rank : 5)	θ value	5.34618e-69 (rank : 3)
Query Neighborhood Hits	189	Target Neighborhood Hits	161	Shared Neighborhood Hits	71
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.806973 (rank : 6)	θ value	1.2325e-65 (rank : 4)
Query Neighborhood Hits	189	Target Neighborhood Hits	171	Shared Neighborhood Hits	71
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP7_HUMAN
NC score	0.804794 (rank : 7)	θ value	1.2049e-28 (rank : 11)
Query Neighborhood Hits	189	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP40_HUMAN
NC score	0.804113 (rank : 8)	θ value	7.80994e-28 (rank : 12)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP48_HUMAN
NC score	0.799697 (rank : 9)	θ value	8.61488e-35 (rank : 7)
Query Neighborhood Hits	189	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.797785 (rank : 10)	θ value	8.61488e-35 (rank : 8)
Query Neighborhood Hits	189	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP47_MOUSE
NC score	0.773755 (rank : 11)	θ value	4.89182e-30 (rank : 9)
Query Neighborhood Hits	189	Target Neighborhood Hits	135	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
NC score	0.771126 (rank : 12)	θ value	1.2049e-28 (rank : 10)
Query Neighborhood Hits	189	Target Neighborhood Hits	149	Shared Neighborhood Hits	76
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP18_HUMAN
NC score	0.754726 (rank : 13)	θ value	4.74913e-17 (rank : 18)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP46_HUMAN
NC score	0.744071 (rank : 14)	θ value	2.43343e-21 (rank : 13)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.744071 (rank : 15)	θ value	2.43343e-21 (rank : 14)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP12_HUMAN
NC score	0.740282 (rank : 16)	θ value	2.69047e-20 (rank : 15)
Query Neighborhood Hits	189	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP18_MOUSE
NC score	0.731194 (rank : 17)	θ value	7.58209e-15 (rank : 25)
Query Neighborhood Hits	189	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP36_HUMAN
NC score	0.708691 (rank : 18)	θ value	3.88503e-19 (rank : 16)
Query Neighborhood Hits	189	Target Neighborhood Hits	232	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBPW_MOUSE
NC score	0.697604 (rank : 19)	θ value	6.00763e-12 (rank : 32)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UB17L_HUMAN
NC score	0.695229 (rank : 20)	θ value	3.18553e-13 (rank : 26)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP22_HUMAN
NC score	0.686720 (rank : 21)	θ value	8.95645e-16 (rank : 22)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
NC score	0.683780 (rank : 22)	θ value	5.8054e-15 (rank : 24)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.680504 (rank : 23)	θ value	6.85773e-16 (rank : 21)
Query Neighborhood Hits	189	Target Neighborhood Hits	162	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP42_HUMAN
NC score	0.672922 (rank : 24)	θ value	4.74913e-17 (rank : 19)
Query Neighborhood Hits	189	Target Neighborhood Hits	445	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP50_MOUSE
NC score	0.671014 (rank : 25)	θ value	8.95645e-16 (rank : 23)
Query Neighborhood Hits	189	Target Neighborhood Hits	80	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP2_MOUSE
NC score	0.667330 (rank : 26)	θ value	2.13179e-17 (rank : 17)
Query Neighborhood Hits	189	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_HUMAN
NC score	0.665920 (rank : 27)	θ value	1.058e-16 (rank : 20)
Query Neighborhood Hits	189	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP20_HUMAN
NC score	0.662930 (rank : 28)	θ value	2.0648e-12 (rank : 29)
Query Neighborhood Hits	189	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP33_HUMAN
NC score	0.659749 (rank : 29)	θ value	4.16044e-13 (rank : 27)
Query Neighborhood Hits	189	Target Neighborhood Hits	157	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP3_HUMAN
NC score	0.657671 (rank : 30)	θ value	4.59992e-12 (rank : 31)
Query Neighborhood Hits	189	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_MOUSE
NC score	0.657521 (rank : 31)	θ value	1.33837e-11 (rank : 33)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP8_MOUSE
NC score	0.643382 (rank : 32)	θ value	7.09661e-13 (rank : 28)
Query Neighborhood Hits	189	Target Neighborhood Hits	362	Shared Neighborhood Hits	87
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP50_HUMAN
NC score	0.639522 (rank : 33)	θ value	9.59137e-10 (rank : 42)
Query Neighborhood Hits	189	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP21_MOUSE
NC score	0.638605 (rank : 34)	θ value	1.9326e-10 (rank : 37)
Query Neighborhood Hits	189	Target Neighborhood Hits	101	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP21_HUMAN
NC score	0.637307 (rank : 35)	θ value	4.30538e-10 (rank : 38)
Query Neighborhood Hits	189	Target Neighborhood Hits	95	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP44_HUMAN
NC score	0.628150 (rank : 36)	θ value	8.11959e-09 (rank : 47)
Query Neighborhood Hits	189	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_HUMAN
NC score	0.627599 (rank : 37)	θ value	2.13673e-09 (rank : 44)
Query Neighborhood Hits	189	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_MOUSE
NC score	0.626700 (rank : 38)	θ value	2.79066e-09 (rank : 45)
Query Neighborhood Hits	189	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP35_HUMAN
NC score	0.625497 (rank : 39)	θ value	2.98157e-11 (rank : 34)
Query Neighborhood Hits	189	Target Neighborhood Hits	223	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP8_HUMAN
NC score	0.610369 (rank : 40)	θ value	2.0648e-12 (rank : 30)
Query Neighborhood Hits	189	Target Neighborhood Hits	751	Shared Neighborhood Hits	97
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP38_HUMAN
NC score	0.581431 (rank : 41)	θ value	2.36244e-08 (rank : 48)
Query Neighborhood Hits	189	Target Neighborhood Hits	97	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP1_HUMAN
NC score	0.577278 (rank : 42)	θ value	4.1701e-05 (rank : 57)
Query Neighborhood Hits	189	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP16_HUMAN
NC score	0.577190 (rank : 43)	θ value	0.00665767 (rank : 62)
Query Neighborhood Hits	189	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP38_MOUSE
NC score	0.566576 (rank : 44)	θ value	6.43352e-06 (rank : 53)
Query Neighborhood Hits	189	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP11_HUMAN
NC score	0.562726 (rank : 45)	θ value	3.64472e-09 (rank : 46)
Query Neighborhood Hits	189	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP31_HUMAN
NC score	0.559127 (rank : 46)	θ value	1.53129e-07 (rank : 51)
Query Neighborhood Hits	189	Target Neighborhood Hits	293	Shared Neighborhood Hits	78
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP14_HUMAN
NC score	0.556619 (rank : 47)	θ value	8.40245e-06 (rank : 54)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP15_HUMAN
NC score	0.556233 (rank : 48)	θ value	8.97725e-08 (rank : 49)
Query Neighborhood Hits	189	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
NC score	0.555629 (rank : 49)	θ value	1.17247e-07 (rank : 50)
Query Neighborhood Hits	189	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP4_MOUSE
NC score	0.554672 (rank : 50)	θ value	5.62301e-10 (rank : 41)
Query Neighborhood Hits	189	Target Neighborhood Hits	90	Shared Neighborhood Hits	70
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP4_HUMAN
NC score	0.553601 (rank : 51)	θ value	1.63604e-09 (rank : 43)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP43_MOUSE
NC score	0.541165 (rank : 52)	θ value	0.000121331 (rank : 58)
Query Neighborhood Hits	189	Target Neighborhood Hits	130	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_HUMAN
NC score	0.541006 (rank : 53)	θ value	1.87187e-05 (rank : 56)
Query Neighborhood Hits	189	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP14_MOUSE
NC score	0.529442 (rank : 54)	θ value	1.09739e-05 (rank : 55)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP30_HUMAN
NC score	0.513909 (rank : 55)	θ value	0.0113563 (rank : 63)
Query Neighborhood Hits	189	Target Neighborhood Hits	94	Shared Neighborhood Hits	67
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP28_MOUSE
NC score	0.507887 (rank : 56)	θ value	6.64225e-11 (rank : 35)
Query Neighborhood Hits	189	Target Neighborhood Hits	178	Shared Neighborhood Hits	71
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
NC score	0.507163 (rank : 57)	θ value	5.62301e-10 (rank : 40)
Query Neighborhood Hits	189	Target Neighborhood Hits	117	Shared Neighborhood Hits	73
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP25_MOUSE
NC score	0.496003 (rank : 58)	θ value	1.47974e-10 (rank : 36)
Query Neighborhood Hits	189	Target Neighborhood Hits	116	Shared Neighborhood Hits	69
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP37_HUMAN
NC score	0.495691 (rank : 59)	θ value	2.88788e-06 (rank : 52)
Query Neighborhood Hits	189	Target Neighborhood Hits	208	Shared Neighborhood Hits	80
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP25_HUMAN
NC score	0.491152 (rank : 60)	θ value	4.30538e-10 (rank : 39)
Query Neighborhood Hits	189	Target Neighborhood Hits	124	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP10_HUMAN
NC score	0.442053 (rank : 61)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	189	Target Neighborhood Hits	153	Shared Neighborhood Hits	68
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_MOUSE
NC score	0.441285 (rank : 62)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	189	Target Neighborhood Hits	150	Shared Neighborhood Hits	71
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP32_HUMAN
NC score	0.435386 (rank : 63)	θ value	0.0252991 (rank : 67)
Query Neighborhood Hits	189	Target Neighborhood Hits	170	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP6_HUMAN
NC score	0.407430 (rank : 64)	θ value	0.0563607 (rank : 70)
Query Neighborhood Hits	189	Target Neighborhood Hits	188	Shared Neighborhood Hits	70
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP29_HUMAN
NC score	0.402126 (rank : 65)	θ value	0.0563607 (rank : 69)
Query Neighborhood Hits	189	Target Neighborhood Hits	94	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

SNUT2_MOUSE
NC score	0.398042 (rank : 66)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	189	Target Neighborhood Hits	80	Shared Neighborhood Hits	57
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
NC score	0.388015 (rank : 67)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	189	Target Neighborhood Hits	79	Shared Neighborhood Hits	56
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP5_MOUSE
NC score	0.377448 (rank : 68)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	189	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_HUMAN
NC score	0.376578 (rank : 69)	θ value	0.0736092 (rank : 72)
Query Neighborhood Hits	189	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP13_HUMAN
NC score	0.371206 (rank : 70)	θ value	0.0252991 (rank : 66)
Query Neighborhood Hits	189	Target Neighborhood Hits	99	Shared Neighborhood Hits	70
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP26_HUMAN
NC score	0.369748 (rank : 71)	θ value	0.279714 (rank : 83)
Query Neighborhood Hits	189	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP29_MOUSE
NC score	0.364957 (rank : 72)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	189	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_MOUSE
NC score	0.294343 (rank : 73)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	189	Target Neighborhood Hits	107	Shared Neighborhood Hits	67
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

DMP1_HUMAN
NC score	0.111280 (rank : 74)	θ value	0.00390308 (rank : 60)
Query Neighborhood Hits	189	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DSPP_MOUSE
NC score	0.099682 (rank : 75)	θ value	0.0148317 (rank : 64)
Query Neighborhood Hits	189	Target Neighborhood Hits	491	Shared Neighborhood Hits	38
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_HUMAN
NC score	0.096718 (rank : 76)	θ value	0.000786445 (rank : 59)
Query Neighborhood Hits	189	Target Neighborhood Hits	645	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DMP1_MOUSE
NC score	0.079409 (rank : 77)	θ value	0.125558 (rank : 74)
Query Neighborhood Hits	189	Target Neighborhood Hits	498	Shared Neighborhood Hits	40
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

PMS2_HUMAN
NC score	0.066808 (rank : 78)	θ value	0.0193708 (rank : 65)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

LEO1_MOUSE
NC score	0.065385 (rank : 79)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	189	Target Neighborhood Hits	946	Shared Neighborhood Hits	59
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.064541 (rank : 80)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	189	Target Neighborhood Hits	958	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

BRAP_MOUSE
NC score	0.063991 (rank : 81)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	189	Target Neighborhood Hits	409	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

IWS1_MOUSE
NC score	0.063739 (rank : 82)	θ value	0.163984 (rank : 76)
Query Neighborhood Hits	189	Target Neighborhood Hits	1258	Shared Neighborhood Hits	65
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_HUMAN
NC score	0.063231 (rank : 83)	θ value	0.0736092 (rank : 71)
Query Neighborhood Hits	189	Target Neighborhood Hits	1241	Shared Neighborhood Hits	58
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BRAP_HUMAN
NC score	0.055869 (rank : 84)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	189	Target Neighborhood Hits	560	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

T2FA_HUMAN
NC score	0.055185 (rank : 85)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	189	Target Neighborhood Hits	228	Shared Neighborhood Hits	23
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

FILA_HUMAN
NC score	0.054433 (rank : 86)	θ value	0.21417 (rank : 77)
Query Neighborhood Hits	189	Target Neighborhood Hits	685	Shared Neighborhood Hits	40
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

LRRF1_MOUSE
NC score	0.052273 (rank : 87)	θ value	0.47712 (rank : 88)
Query Neighborhood Hits	189	Target Neighborhood Hits	440	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

RNF34_MOUSE
NC score	0.050388 (rank : 88)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	189	Target Neighborhood Hits	160	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

MYST4_HUMAN
NC score	0.049676 (rank : 89)	θ value	0.00390308 (rank : 61)
Query Neighborhood Hits	189	Target Neighborhood Hits	671	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

HDAC6_HUMAN
NC score	0.047433 (rank : 90)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	189	Target Neighborhood Hits	145	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

RSF1_HUMAN
NC score	0.045730 (rank : 91)	θ value	0.47712 (rank : 89)
Query Neighborhood Hits	189	Target Neighborhood Hits	539	Shared Neighborhood Hits	32
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

MYST3_HUMAN
NC score	0.044621 (rank : 92)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	189	Target Neighborhood Hits	772	Shared Neighborhood Hits	40
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
NC score	0.043787 (rank : 93)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	189	Target Neighborhood Hits	688	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

WAPL_HUMAN
NC score	0.039929 (rank : 94)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	189	Target Neighborhood Hits	122	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

ATRX_MOUSE
NC score	0.039824 (rank : 95)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	189	Target Neighborhood Hits	682	Shared Neighborhood Hits	47
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

RERE_MOUSE
NC score	0.038863 (rank : 96)	θ value	0.125558 (rank : 75)
Query Neighborhood Hits	189	Target Neighborhood Hits	785	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TOM1_HUMAN
NC score	0.038774 (rank : 97)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	189	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

ZCHC7_HUMAN
NC score	0.037422 (rank : 98)	θ value	0.47712 (rank : 90)
Query Neighborhood Hits	189	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

MYT1L_HUMAN
NC score	0.035923 (rank : 99)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	189	Target Neighborhood Hits	471	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

NPHP1_HUMAN
NC score	0.035663 (rank : 100)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	189	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

CJ012_HUMAN
NC score	0.035305 (rank : 101)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	189	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

MYT1L_MOUSE
NC score	0.034902 (rank : 102)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	189	Target Neighborhood Hits	461	Shared Neighborhood Hits	24
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

NALP5_MOUSE
NC score	0.034630 (rank : 103)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	189	Target Neighborhood Hits	560	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

CCD55_MOUSE
NC score	0.034232 (rank : 104)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	189	Target Neighborhood Hits	519	Shared Neighborhood Hits	35
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ABTAP_MOUSE
NC score	0.032335 (rank : 105)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	189	Target Neighborhood Hits	381	Shared Neighborhood Hits	23
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ARI5B_HUMAN
NC score	0.032318 (rank : 106)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	189	Target Neighborhood Hits	328	Shared Neighborhood Hits	25
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

RFFL_HUMAN
NC score	0.031885 (rank : 107)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	189	Target Neighborhood Hits	175	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

ANC5_HUMAN
NC score	0.031396 (rank : 108)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	189	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJX4, Q8N4H7, Q9BQD4	Gene names	ANAPC5, APC5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

TOM1_MOUSE
NC score	0.031005 (rank : 109)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	189	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

RERE_HUMAN
NC score	0.030920 (rank : 110)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	189	Target Neighborhood Hits	779	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RPTN_HUMAN
NC score	0.030266 (rank : 111)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	189	Target Neighborhood Hits	406	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

GCP5_HUMAN
NC score	0.029107 (rank : 112)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	189	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q96RT8, Q96PY8	Gene names	TUBGCP5, GCP5, KIAA1899
Domain Architecture
Description	Gamma-tubulin complex component 5 (GCP-5).

CI082_HUMAN
NC score	0.028670 (rank : 113)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	189	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

CDKN3_HUMAN
NC score	0.028210 (rank : 114)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	189	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

FA44A_HUMAN
NC score	0.027240 (rank : 115)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	189	Target Neighborhood Hits	280	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

PP2CG_MOUSE
NC score	0.027203 (rank : 116)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	189	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

SMRC1_MOUSE
NC score	0.026645 (rank : 117)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	189	Target Neighborhood Hits	459	Shared Neighborhood Hits	30
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

TP4AP_HUMAN
NC score	0.026639 (rank : 118)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	189	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEL6, Q96H82, Q9BVB8, Q9H429, Q9UFS6	Gene names	TRPC4AP, C20orf188, TRRP4AP
Domain Architecture	No domain graphic available
Description	Trpc4-associated protein (Short transient receptor potential channel 4-associated protein) (Trp4-associated protein) (TAP1 protein) (TNF- receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS).

TP4AP_MOUSE
NC score	0.026589 (rank : 119)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	189	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLV2, Q920J6, Q99L03	Gene names	Trpc4ap, Trrp4ap
Domain Architecture	No domain graphic available
Description	Trpc4-associated protein (Trp4-associated protein) (Short transient receptor potential channel 4-associated protein) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS) (TAP1 protein) (Rabex-5/Rin2-interacting protein).

ARY2_MOUSE
NC score	0.026256 (rank : 120)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	189	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P50295	Gene names	Nat2, Aac2
Domain Architecture
Description	Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2).

RPTN_MOUSE
NC score	0.026092 (rank : 121)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	189	Target Neighborhood Hits	650	Shared Neighborhood Hits	34
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

K1718_MOUSE
NC score	0.025965 (rank : 122)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	189	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

CP007_HUMAN
NC score	0.025177 (rank : 123)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	189	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

ERCC5_HUMAN
NC score	0.024901 (rank : 124)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	189	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

DHSB_MOUSE
NC score	0.023771 (rank : 125)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	189	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQA3, Q3TF82, Q9DC91	Gene names	Sdhb
Domain Architecture	No domain graphic available
Description	Succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial precursor (EC 1.3.5.1) (Ip) (Iron-sulfur subunit of complex II).

K0020_HUMAN
NC score	0.023742 (rank : 126)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	189	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q15397, Q547G7, Q5SZY9, Q6IB47, Q96B27, Q96L78, Q96L79, Q96L80	Gene names	KIAA0020, XTP5
Domain Architecture	No domain graphic available
Description	Protein KIAA0020 (HBV X-transactivated gene 5 protein) (Minor histocompatibility antigen HA-8) (HLA-HA8).

DHSB_HUMAN
NC score	0.023608 (rank : 127)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	189	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	P21912, Q9NQ12	Gene names	SDHB, SDH, SDH1
Domain Architecture	No domain graphic available
Description	Succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial precursor (EC 1.3.5.1) (Ip) (Iron-sulfur subunit of complex II).

BASP_MOUSE
NC score	0.023100 (rank : 128)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	189	Target Neighborhood Hits	260	Shared Neighborhood Hits	12
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

PROM1_MOUSE
NC score	0.022150 (rank : 129)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	189	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

MPP8_HUMAN
NC score	0.021377 (rank : 130)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	189	Target Neighborhood Hits	948	Shared Neighborhood Hits	43
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CLSPN_HUMAN
NC score	0.021238 (rank : 131)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	189	Target Neighborhood Hits	433	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

PININ_MOUSE
NC score	0.020852 (rank : 132)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	189	Target Neighborhood Hits	777	Shared Neighborhood Hits	43
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

TCOF_HUMAN
NC score	0.020326 (rank : 133)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	189	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

PAR10_HUMAN
NC score	0.020270 (rank : 134)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	189	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

RRBP1_MOUSE
NC score	0.019369 (rank : 135)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	189	Target Neighborhood Hits	1650	Shared Neighborhood Hits	57
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ARY1_HUMAN
NC score	0.019003 (rank : 136)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	189	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P18440, O15159, O15300	Gene names	NAT1, AAC1
Domain Architecture
Description	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Arylamine N-acetyltransferase, monomorphic) (MNAT) (N- acetyltransferase type 1) (NAT-1).

MSH6_HUMAN
NC score	0.018867 (rank : 137)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

UBR1_MOUSE
NC score	0.016558 (rank : 138)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	189	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

BAZ1A_HUMAN
NC score	0.016243 (rank : 139)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	189	Target Neighborhood Hits	693	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

NF2L3_MOUSE
NC score	0.015736 (rank : 140)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	189	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

P52K_HUMAN
NC score	0.015411 (rank : 141)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	189	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

LMNB1_MOUSE
NC score	0.014755 (rank : 142)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	189	Target Neighborhood Hits	719	Shared Neighborhood Hits	20
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

MK67I_MOUSE
NC score	0.014134 (rank : 143)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	189	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VE6, Q8BMV9, Q8BVL4	Gene names	Mki67ip, Nifk
Domain Architecture	No domain graphic available
Description	MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar protein interacting with the FHA domain of pKI-67) (mNIFK).

MPP10_HUMAN
NC score	0.013891 (rank : 144)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	189	Target Neighborhood Hits	306	Shared Neighborhood Hits	20
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

UBR1_HUMAN
NC score	0.013754 (rank : 145)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	189	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

K0460_HUMAN
NC score	0.013579 (rank : 146)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	189	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

LMNB2_MOUSE
NC score	0.013415 (rank : 147)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	189	Target Neighborhood Hits	674	Shared Neighborhood Hits	16
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

MA2A1_HUMAN
NC score	0.013007 (rank : 148)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	189	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q16706, Q16767	Gene names	MAN2A1, MANA2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1).

CENPJ_HUMAN
NC score	0.012812 (rank : 149)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	189	Target Neighborhood Hits	721	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

LMNB1_HUMAN
NC score	0.012552 (rank : 150)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	189	Target Neighborhood Hits	714	Shared Neighborhood Hits	21
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

NOS2_MOUSE
NC score	0.012407 (rank : 151)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	189	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

RTN1_MOUSE
NC score	0.012151 (rank : 152)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	189	Target Neighborhood Hits	189	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

CHD2_HUMAN
NC score	0.011735 (rank : 153)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	189	Target Neighborhood Hits	360	Shared Neighborhood Hits	25
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

MA2A1_MOUSE
NC score	0.011625 (rank : 154)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	189	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

ISK5_HUMAN
NC score	0.011343 (rank : 155)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	189	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

ZAR1_HUMAN
NC score	0.011291 (rank : 156)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	189	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

LMNB2_HUMAN
NC score	0.011115 (rank : 157)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	189	Target Neighborhood Hits	723	Shared Neighborhood Hits	17
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

NALP4_HUMAN
NC score	0.010619 (rank : 158)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	189	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

MACF4_HUMAN
NC score	0.010420 (rank : 159)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	189	Target Neighborhood Hits	1321	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MLL3_HUMAN
NC score	0.010306 (rank : 160)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	189	Target Neighborhood Hits	1644	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RGS12_HUMAN
NC score	0.010304 (rank : 161)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	189	Target Neighborhood Hits	333	Shared Neighborhood Hits	10
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

DCR1A_MOUSE
NC score	0.010119 (rank : 162)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	189	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

NCOR1_MOUSE
NC score	0.010061 (rank : 163)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	189	Target Neighborhood Hits	521	Shared Neighborhood Hits	29
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

JHD2C_HUMAN
NC score	0.010024 (rank : 164)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	189	Target Neighborhood Hits	279	Shared Neighborhood Hits	19
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

ACET_HUMAN
NC score	0.009982 (rank : 165)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	189	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_HUMAN
NC score	0.009702 (rank : 166)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	189	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

KI21A_MOUSE
NC score	0.008542 (rank : 167)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	189	Target Neighborhood Hits	1317	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

SYNE1_HUMAN
NC score	0.008233 (rank : 168)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	189	Target Neighborhood Hits	1484	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

PDE4A_HUMAN
NC score	0.008082 (rank : 169)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	189	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

COHA1_HUMAN
NC score	0.007666 (rank : 170)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	189	Target Neighborhood Hits	400	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

NUMA1_HUMAN
NC score	0.007596 (rank : 171)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	189	Target Neighborhood Hits	1523	Shared Neighborhood Hits	34
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PTN13_HUMAN
NC score	0.007353 (rank : 172)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	189	Target Neighborhood Hits	471	Shared Neighborhood Hits	18
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

CHIT1_MOUSE
NC score	0.006798 (rank : 173)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	189	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

CD2L2_HUMAN
NC score	0.006597 (rank : 174)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	189	Target Neighborhood Hits	1439	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

ZN447_HUMAN
NC score	0.006410 (rank : 175)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	189	Target Neighborhood Hits	899	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

EMIL3_HUMAN
NC score	0.006299 (rank : 176)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	189	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

CENPE_HUMAN
NC score	0.006194 (rank : 177)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	189	Target Neighborhood Hits	2060	Shared Neighborhood Hits	54
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RYR3_HUMAN
NC score	0.006009 (rank : 178)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	189	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

MKL1_HUMAN
NC score	0.005858 (rank : 179)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	189	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

TMC2_HUMAN
NC score	0.005159 (rank : 180)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	189	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

CTGE5_MOUSE
NC score	0.004582 (rank : 181)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	189	Target Neighborhood Hits	928	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

A16L1_MOUSE
NC score	0.004310 (rank : 182)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	189	Target Neighborhood Hits	776	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

LASS5_MOUSE
NC score	0.004085 (rank : 183)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	189	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6K9, Q3UL17, Q80YB2, Q8BPH6, Q921T8, Q924Z3	Gene names	Lass5, Trh4
Domain Architecture	No domain graphic available
Description	LAG1 longevity assurance homolog 5 (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4).

GBRA1_HUMAN
NC score	0.004077 (rank : 184)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	189	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	P14867, Q8N629	Gene names	GABRA1
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit alpha-1 precursor (GABA(A) receptor subunit alpha-1).

CD2L1_HUMAN
NC score	0.002429 (rank : 185)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	189	Target Neighborhood Hits	1467	Shared Neighborhood Hits	43
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L1_MOUSE
NC score	0.002090 (rank : 186)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	189	Target Neighborhood Hits	1463	Shared Neighborhood Hits	45
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

SEM6D_HUMAN
NC score	0.001570 (rank : 187)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	189	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

CENG2_HUMAN
NC score	0.001547 (rank : 188)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	189	Target Neighborhood Hits	471	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
NC score	0.001212 (rank : 189)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	189	Target Neighborhood Hits	463	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

HIPK3_HUMAN
NC score	-0.002096 (rank : 190)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	189	Target Neighborhood Hits	867	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

KKCC2_MOUSE
NC score	-0.003738 (rank : 191)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	189	Target Neighborhood Hits	855	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C078, Q80TS0, Q8BXM8, Q8C0G3, Q8CH42, Q8QZT7	Gene names	Camkk2, Kiaa0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

KKCC2_HUMAN
NC score	-0.003739 (rank : 192)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	189	Target Neighborhood Hits	852	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RR4, O94883, Q8IUG2, Q8IUG3, Q8N3I4, Q8WY03, Q8WY04, Q8WY05, Q8WY06, Q96RP1, Q96RP2, Q96RR3, Q9BWE9, Q9UER3, Q9UES2, Q9Y5N2	Gene names	CAMKK2, CAMKKB, KIAA0787
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 2 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta).

ZNF12_HUMAN
NC score	-0.004642 (rank : 193)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	189	Target Neighborhood Hits	779	Shared Neighborhood Hits	5
SwissProt Accessions	P17014, Q9ULZ6	Gene names	ZNF12, GIOT3, KOX3, ZNF325
Domain Architecture	No domain graphic available
Description	Zinc finger protein 12 (Zinc finger protein KOX3) (Zinc finger protein 325) (Gonadotropin-inducible transcription repressor 3) (GIOT-3).

ZN642_HUMAN
NC score	-0.005149 (rank : 194)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	189	Target Neighborhood Hits	744	Shared Neighborhood Hits	5
SwissProt Accessions	Q49AA0, Q5SWM5, Q6ZWK8	Gene names	ZNF642
Domain Architecture	No domain graphic available
Description	Zinc finger protein 642.