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Network neighborhood for query Sequence : UBP38_HUMAN

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UBP38_HUMAN
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP38_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
θ value	0 (rank : 2)	NC score	0.994471 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP35_HUMAN
θ value	1.28067e-163 (rank : 3)	NC score	0.942585 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	223	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP50_MOUSE
θ value	4.91457e-14 (rank : 4)	NC score	0.710232 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP46_HUMAN
θ value	6.41864e-14 (rank : 5)	NC score	0.712347 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	6.41864e-14 (rank : 6)	NC score	0.712347 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP3_MOUSE
θ value	3.18553e-13 (rank : 7)	NC score	0.683687 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP8_MOUSE
θ value	1.2105e-12 (rank : 8)	NC score	0.666239 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	362	Shared Neighborhood Hits	72
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP47_HUMAN
θ value	1.58096e-12 (rank : 9)	NC score	0.652918 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP2_MOUSE
θ value	2.69671e-12 (rank : 10)	NC score	0.687289 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP12_HUMAN
θ value	6.00763e-12 (rank : 11)	NC score	0.708959 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP2_HUMAN
θ value	6.00763e-12 (rank : 12)	NC score	0.683318 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP47_MOUSE
θ value	6.00763e-12 (rank : 13)	NC score	0.652072 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	135	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP33_HUMAN
θ value	7.84624e-12 (rank : 14)	NC score	0.677595 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP8_HUMAN
θ value	3.89403e-11 (rank : 15)	NC score	0.629719 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	751	Shared Neighborhood Hits	73
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP20_HUMAN
θ value	6.64225e-11 (rank : 16)	NC score	0.669920 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	113	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

USP9Y_HUMAN
θ value	1.133e-10 (rank : 17)	NC score	0.578156 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP21_HUMAN
θ value	1.47974e-10 (rank : 18)	NC score	0.674288 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP32_HUMAN
θ value	3.29651e-10 (rank : 19)	NC score	0.557904 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	170	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

USP9X_MOUSE
θ value	3.29651e-10 (rank : 20)	NC score	0.572375 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	171	Shared Neighborhood Hits	71
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9X_HUMAN
θ value	4.30538e-10 (rank : 21)	NC score	0.569985 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	161	Shared Neighborhood Hits	71
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP48_MOUSE
θ value	5.62301e-10 (rank : 22)	NC score	0.673915 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP16_HUMAN
θ value	7.34386e-10 (rank : 23)	NC score	0.672197 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP21_MOUSE
θ value	9.59137e-10 (rank : 24)	NC score	0.667867 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP6_HUMAN
θ value	1.25267e-09 (rank : 25)	NC score	0.525345 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP48_HUMAN
θ value	1.63604e-09 (rank : 26)	NC score	0.677282 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP28_MOUSE
θ value	4.76016e-09 (rank : 27)	NC score	0.495522 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	178	Shared Neighborhood Hits	70
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP50_HUMAN
θ value	6.21693e-09 (rank : 28)	NC score	0.678001 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP15_MOUSE
θ value	1.38499e-08 (rank : 29)	NC score	0.610664 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP24_HUMAN
θ value	1.38499e-08 (rank : 30)	NC score	0.630666 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP15_HUMAN
θ value	1.80886e-08 (rank : 31)	NC score	0.609906 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP34_MOUSE
θ value	2.36244e-08 (rank : 32)	NC score	0.581431 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	189	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP28_HUMAN
θ value	4.0297e-08 (rank : 33)	NC score	0.495308 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP4_HUMAN
θ value	4.0297e-08 (rank : 34)	NC score	0.605445 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP18_HUMAN
θ value	8.97725e-08 (rank : 35)	NC score	0.682021 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP43_MOUSE
θ value	8.97725e-08 (rank : 36)	NC score	0.605385 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	130	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP34_HUMAN
θ value	1.17247e-07 (rank : 37)	NC score	0.579832 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	210	Shared Neighborhood Hits	69
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP43_HUMAN
θ value	1.53129e-07 (rank : 38)	NC score	0.605754 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP25_MOUSE
θ value	3.41135e-07 (rank : 39)	NC score	0.472383 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	116	Shared Neighborhood Hits	70
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP14_MOUSE
θ value	4.45536e-07 (rank : 40)	NC score	0.570014 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP22_HUMAN
θ value	4.45536e-07 (rank : 41)	NC score	0.651666 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP4_MOUSE
θ value	4.45536e-07 (rank : 42)	NC score	0.599257 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	90	Shared Neighborhood Hits	71
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP3_HUMAN
θ value	5.81887e-07 (rank : 43)	NC score	0.650972 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP25_HUMAN
θ value	7.59969e-07 (rank : 44)	NC score	0.469961 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP22_MOUSE
θ value	9.92553e-07 (rank : 45)	NC score	0.650945 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP11_HUMAN
θ value	1.29631e-06 (rank : 46)	NC score	0.602157 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP14_HUMAN
θ value	1.69304e-06 (rank : 47)	NC score	0.577217 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP49_MOUSE
θ value	1.69304e-06 (rank : 48)	NC score	0.619105 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP7_HUMAN
θ value	1.69304e-06 (rank : 49)	NC score	0.638491 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBPW_MOUSE
θ value	2.21117e-06 (rank : 50)	NC score	0.659077 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP51_HUMAN
θ value	2.88788e-06 (rank : 51)	NC score	0.645920 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	162	Shared Neighborhood Hits	74
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP31_HUMAN
θ value	6.43352e-06 (rank : 52)	NC score	0.586727 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	293	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UB17L_HUMAN
θ value	8.40245e-06 (rank : 53)	NC score	0.629652 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	83	Shared Neighborhood Hits	70
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP36_HUMAN
θ value	1.09739e-05 (rank : 54)	NC score	0.631144 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	232	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP42_HUMAN
θ value	1.09739e-05 (rank : 55)	NC score	0.607956 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	445	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP1_HUMAN
θ value	4.1701e-05 (rank : 56)	NC score	0.589013 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	259	Shared Neighborhood Hits	72
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP13_HUMAN
θ value	5.44631e-05 (rank : 57)	NC score	0.460770 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	99	Shared Neighborhood Hits	70
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP37_HUMAN
θ value	5.44631e-05 (rank : 58)	NC score	0.533881 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	208	Shared Neighborhood Hits	72
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP40_HUMAN
θ value	0.000121331 (rank : 59)	NC score	0.617372 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP44_HUMAN
θ value	0.000121331 (rank : 60)	NC score	0.611073 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_HUMAN
θ value	0.00035302 (rank : 61)	NC score	0.607324 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP5_HUMAN
θ value	0.00035302 (rank : 62)	NC score	0.443796 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	0.00035302 (rank : 63)	NC score	0.442445 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP18_MOUSE
θ value	0.00102713 (rank : 64)	NC score	0.637594 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP29_HUMAN
θ value	0.00298849 (rank : 65)	NC score	0.462585 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_HUMAN
θ value	0.0113563 (rank : 66)	NC score	0.439239 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

CENPE_HUMAN
θ value	0.0148317 (rank : 67)	NC score	0.007894 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	2060	Shared Neighborhood Hits	14
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

UBP29_MOUSE
θ value	0.0252991 (rank : 68)	NC score	0.437180 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP10_MOUSE
θ value	0.0330416 (rank : 69)	NC score	0.492363 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	150	Shared Neighborhood Hits	67
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_HUMAN
θ value	0.0431538 (rank : 70)	NC score	0.488404 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP30_HUMAN
θ value	0.125558 (rank : 71)	NC score	0.539628 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

CABIN_HUMAN
θ value	0.163984 (rank : 72)	NC score	0.055871 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	490	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

ZN445_HUMAN
θ value	0.163984 (rank : 73)	NC score	-0.001341 (rank : 101)
Query Neighborhood Hits	97	Target Neighborhood Hits	764	Shared Neighborhood Hits	4
SwissProt Accessions	P59923	Gene names	ZNF445, ZNF168
Domain Architecture
Description	Zinc finger protein 445.

PCDB5_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.004758 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5E4, Q9UFU9	Gene names	PCDHB5
Domain Architecture
Description	Protocadherin beta 5 precursor (PCDH-beta5).

UBP53_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.078691 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBR2_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.023323 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UBP53_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.079355 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

NRAP_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.010797 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

SUHW3_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.001089 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	695	Shared Neighborhood Hits	4
SwissProt Accessions	Q8ND82, Q9NXR3	Gene names	SUHW3
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

TEP1_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.011852 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

TTC16_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.014508 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	417	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

NFAT5_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.010387 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

UBP26_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.350187 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	68
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBR2_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.022569 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

AP1G1_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.015292 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.015352 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

CNKR2_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.009245 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

MAMC2_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.015471 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NOTC2_HUMAN
θ value	5.27518 (rank : 89)	NC score	-0.001817 (rank : 103)
Query Neighborhood Hits	97	Target Neighborhood Hits	1113	Shared Neighborhood Hits	3
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SPTA1_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.004003 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	675	Shared Neighborhood Hits	4
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

IF2B2_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.010282 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.010816 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

NOTC4_HUMAN
θ value	6.88961 (rank : 93)	NC score	-0.001651 (rank : 102)
Query Neighborhood Hits	97	Target Neighborhood Hits	905	Shared Neighborhood Hits	4
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

REST_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.000692 (rank : 100)
Query Neighborhood Hits	97	Target Neighborhood Hits	1605	Shared Neighborhood Hits	9
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ARMX5_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.009802 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1M9, Q68DB4, Q9BVZ3, Q9H969	Gene names	ARMCX5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

CCP3_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.007161 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKK0, Q9CX87	Gene names	Dscr1l2
Domain Architecture
Description	Calcipressin-3 (Down syndrome candidate region 1-like protein 2) (Myocyte-enriched calcineurin-interacting protein 3) (MCIP3).

ZN195_HUMAN
θ value	8.99809 (rank : 97)	NC score	-0.004104 (rank : 104)
Query Neighborhood Hits	97	Target Neighborhood Hits	760	Shared Neighborhood Hits	4
SwissProt Accessions	O14628	Gene names	ZNF195, ZNFP104
Domain Architecture
Description	Zinc finger protein 195.

BRAP_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.065218 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	560	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.074460 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	409	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

GGNB1_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.062751 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

SNUT2_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.375878 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.385914 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	80	Shared Neighborhood Hits	58
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP54_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.051928 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.052228 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

Hits sorted by NC score

UBP38_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
NC score	0.994471 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP35_HUMAN
NC score	0.942585 (rank : 3)	θ value	1.28067e-163 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	223	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP46_HUMAN
NC score	0.712347 (rank : 4)	θ value	6.41864e-14 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.712347 (rank : 5)	θ value	6.41864e-14 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP50_MOUSE
NC score	0.710232 (rank : 6)	θ value	4.91457e-14 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP12_HUMAN
NC score	0.708959 (rank : 7)	θ value	6.00763e-12 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP2_MOUSE
NC score	0.687289 (rank : 8)	θ value	2.69671e-12 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP3_MOUSE
NC score	0.683687 (rank : 9)	θ value	3.18553e-13 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP2_HUMAN
NC score	0.683318 (rank : 10)	θ value	6.00763e-12 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP18_HUMAN
NC score	0.682021 (rank : 11)	θ value	8.97725e-08 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP50_HUMAN
NC score	0.678001 (rank : 12)	θ value	6.21693e-09 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP33_HUMAN
NC score	0.677595 (rank : 13)	θ value	7.84624e-12 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP48_HUMAN
NC score	0.677282 (rank : 14)	θ value	1.63604e-09 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP21_HUMAN
NC score	0.674288 (rank : 15)	θ value	1.47974e-10 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP48_MOUSE
NC score	0.673915 (rank : 16)	θ value	5.62301e-10 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP16_HUMAN
NC score	0.672197 (rank : 17)	θ value	7.34386e-10 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP20_HUMAN
NC score	0.669920 (rank : 18)	θ value	6.64225e-11 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	113	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP21_MOUSE
NC score	0.667867 (rank : 19)	θ value	9.59137e-10 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP8_MOUSE
NC score	0.666239 (rank : 20)	θ value	1.2105e-12 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	362	Shared Neighborhood Hits	72
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBPW_MOUSE
NC score	0.659077 (rank : 21)	θ value	2.21117e-06 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP47_HUMAN
NC score	0.652918 (rank : 22)	θ value	1.58096e-12 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_MOUSE
NC score	0.652072 (rank : 23)	θ value	6.00763e-12 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	135	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP22_HUMAN
NC score	0.651666 (rank : 24)	θ value	4.45536e-07 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP3_HUMAN
NC score	0.650972 (rank : 25)	θ value	5.81887e-07 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP22_MOUSE
NC score	0.650945 (rank : 26)	θ value	9.92553e-07 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.645920 (rank : 27)	θ value	2.88788e-06 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	162	Shared Neighborhood Hits	74
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP7_HUMAN
NC score	0.638491 (rank : 28)	θ value	1.69304e-06 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP18_MOUSE
NC score	0.637594 (rank : 29)	θ value	0.00102713 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP36_HUMAN
NC score	0.631144 (rank : 30)	θ value	1.09739e-05 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	232	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP24_HUMAN
NC score	0.630666 (rank : 31)	θ value	1.38499e-08 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP8_HUMAN
NC score	0.629719 (rank : 32)	θ value	3.89403e-11 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	751	Shared Neighborhood Hits	73
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UB17L_HUMAN
NC score	0.629652 (rank : 33)	θ value	8.40245e-06 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	83	Shared Neighborhood Hits	70
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP49_MOUSE
NC score	0.619105 (rank : 34)	θ value	1.69304e-06 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP40_HUMAN
NC score	0.617372 (rank : 35)	θ value	0.000121331 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP44_HUMAN
NC score	0.611073 (rank : 36)	θ value	0.000121331 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP15_MOUSE
NC score	0.610664 (rank : 37)	θ value	1.38499e-08 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP15_HUMAN
NC score	0.609906 (rank : 38)	θ value	1.80886e-08 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP42_HUMAN
NC score	0.607956 (rank : 39)	θ value	1.09739e-05 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	445	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP49_HUMAN
NC score	0.607324 (rank : 40)	θ value	0.00035302 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP43_HUMAN
NC score	0.605754 (rank : 41)	θ value	1.53129e-07 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP4_HUMAN
NC score	0.605445 (rank : 42)	θ value	4.0297e-08 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP43_MOUSE
NC score	0.605385 (rank : 43)	θ value	8.97725e-08 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	130	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP11_HUMAN
NC score	0.602157 (rank : 44)	θ value	1.29631e-06 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP4_MOUSE
NC score	0.599257 (rank : 45)	θ value	4.45536e-07 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	90	Shared Neighborhood Hits	71
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP1_HUMAN
NC score	0.589013 (rank : 46)	θ value	4.1701e-05 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	259	Shared Neighborhood Hits	72
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP31_HUMAN
NC score	0.586727 (rank : 47)	θ value	6.43352e-06 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	293	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP34_MOUSE
NC score	0.581431 (rank : 48)	θ value	2.36244e-08 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	189	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.579832 (rank : 49)	θ value	1.17247e-07 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	210	Shared Neighborhood Hits	69
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

USP9Y_HUMAN
NC score	0.578156 (rank : 50)	θ value	1.133e-10 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP14_HUMAN
NC score	0.577217 (rank : 51)	θ value	1.69304e-06 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

USP9X_MOUSE
NC score	0.572375 (rank : 52)	θ value	3.29651e-10 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	171	Shared Neighborhood Hits	71
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP14_MOUSE
NC score	0.570014 (rank : 53)	θ value	4.45536e-07 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

USP9X_HUMAN
NC score	0.569985 (rank : 54)	θ value	4.30538e-10 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	161	Shared Neighborhood Hits	71
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP32_HUMAN
NC score	0.557904 (rank : 55)	θ value	3.29651e-10 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	170	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP30_HUMAN
NC score	0.539628 (rank : 56)	θ value	0.125558 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP37_HUMAN
NC score	0.533881 (rank : 57)	θ value	5.44631e-05 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	208	Shared Neighborhood Hits	72
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP6_HUMAN
NC score	0.525345 (rank : 58)	θ value	1.25267e-09 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP28_MOUSE
NC score	0.495522 (rank : 59)	θ value	4.76016e-09 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	178	Shared Neighborhood Hits	70
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
NC score	0.495308 (rank : 60)	θ value	4.0297e-08 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP10_MOUSE
NC score	0.492363 (rank : 61)	θ value	0.0330416 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	150	Shared Neighborhood Hits	67
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_HUMAN
NC score	0.488404 (rank : 62)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP25_MOUSE
NC score	0.472383 (rank : 63)	θ value	3.41135e-07 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	116	Shared Neighborhood Hits	70
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.469961 (rank : 64)	θ value	7.59969e-07 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP29_HUMAN
NC score	0.462585 (rank : 65)	θ value	0.00298849 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP13_HUMAN
NC score	0.460770 (rank : 66)	θ value	5.44631e-05 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	99	Shared Neighborhood Hits	70
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP5_HUMAN
NC score	0.443796 (rank : 67)	θ value	0.00035302 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
NC score	0.442445 (rank : 68)	θ value	0.00035302 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP26_HUMAN
NC score	0.439239 (rank : 69)	θ value	0.0113563 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP29_MOUSE
NC score	0.437180 (rank : 70)	θ value	0.0252991 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

SNUT2_MOUSE
NC score	0.385914 (rank : 71)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	97	Target Neighborhood Hits	80	Shared Neighborhood Hits	58
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
NC score	0.375878 (rank : 72)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	97	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP26_MOUSE
NC score	0.350187 (rank : 73)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	68
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP53_HUMAN
NC score	0.079355 (rank : 74)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP53_MOUSE
NC score	0.078691 (rank : 75)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

BRAP_MOUSE
NC score	0.074460 (rank : 76)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	409	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRAP_HUMAN
NC score	0.065218 (rank : 77)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	560	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

GGNB1_MOUSE
NC score	0.062751 (rank : 78)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	97	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

CABIN_HUMAN
NC score	0.055871 (rank : 79)	θ value	0.163984 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	490	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

UBP54_MOUSE
NC score	0.052228 (rank : 80)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_HUMAN
NC score	0.051928 (rank : 81)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	97	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBR2_MOUSE
NC score	0.023323 (rank : 82)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UBR2_HUMAN
NC score	0.022569 (rank : 83)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

MAMC2_MOUSE
NC score	0.015471 (rank : 84)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

AP1G1_MOUSE
NC score	0.015352 (rank : 85)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_HUMAN
NC score	0.015292 (rank : 86)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

TTC16_HUMAN
NC score	0.014508 (rank : 87)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	417	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TEP1_MOUSE
NC score	0.011852 (rank : 88)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	344	Shared Neighborhood Hits	3
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

IF2B2_MOUSE
NC score	0.010816 (rank : 89)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

NRAP_HUMAN
NC score	0.010797 (rank : 90)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

NFAT5_MOUSE
NC score	0.010387 (rank : 91)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

IF2B2_HUMAN
NC score	0.010282 (rank : 92)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

ARMX5_HUMAN
NC score	0.009802 (rank : 93)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1M9, Q68DB4, Q9BVZ3, Q9H969	Gene names	ARMCX5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

CNKR2_HUMAN
NC score	0.009245 (rank : 94)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CENPE_HUMAN
NC score	0.007894 (rank : 95)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	2060	Shared Neighborhood Hits	14
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CCP3_MOUSE
NC score	0.007161 (rank : 96)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKK0, Q9CX87	Gene names	Dscr1l2
Domain Architecture
Description	Calcipressin-3 (Down syndrome candidate region 1-like protein 2) (Myocyte-enriched calcineurin-interacting protein 3) (MCIP3).

PCDB5_HUMAN
NC score	0.004758 (rank : 97)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5E4, Q9UFU9	Gene names	PCDHB5
Domain Architecture
Description	Protocadherin beta 5 precursor (PCDH-beta5).

SPTA1_MOUSE
NC score	0.004003 (rank : 98)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	675	Shared Neighborhood Hits	4
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SUHW3_HUMAN
NC score	0.001089 (rank : 99)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	695	Shared Neighborhood Hits	4
SwissProt Accessions	Q8ND82, Q9NXR3	Gene names	SUHW3
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

REST_HUMAN
NC score	0.000692 (rank : 100)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	1605	Shared Neighborhood Hits	9
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ZN445_HUMAN
NC score	-0.001341 (rank : 101)	θ value	0.163984 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	764	Shared Neighborhood Hits	4
SwissProt Accessions	P59923	Gene names	ZNF445, ZNF168
Domain Architecture
Description	Zinc finger protein 445.

NOTC4_HUMAN
NC score	-0.001651 (rank : 102)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	905	Shared Neighborhood Hits	4
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC2_HUMAN
NC score	-0.001817 (rank : 103)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	1113	Shared Neighborhood Hits	3
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZN195_HUMAN
NC score	-0.004104 (rank : 104)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	760	Shared Neighborhood Hits	4
SwissProt Accessions	O14628	Gene names	ZNF195, ZNFP104
Domain Architecture
Description	Zinc finger protein 195.