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Network neighborhood for query Sequence : UBP49_HUMAN

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UBP49_HUMAN
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP44_HUMAN
θ value	0 (rank : 1)	NC score	0.992948 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_MOUSE
θ value	0 (rank : 3)	NC score	0.998001 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP3_MOUSE
θ value	8.57503e-51 (rank : 4)	NC score	0.915592 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_HUMAN
θ value	1.36902e-48 (rank : 5)	NC score	0.915932 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP2_MOUSE
θ value	2.19584e-30 (rank : 6)	NC score	0.857638 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_HUMAN
θ value	4.89182e-30 (rank : 7)	NC score	0.856457 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP8_HUMAN
θ value	1.2049e-28 (rank : 8)	NC score	0.792215 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	751	Shared Neighborhood Hits	76
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP22_MOUSE
θ value	2.68423e-28 (rank : 9)	NC score	0.864583 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	87	Shared Neighborhood Hits	77
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
θ value	7.80994e-28 (rank : 10)	NC score	0.866243 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	87	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
θ value	3.87602e-27 (rank : 11)	NC score	0.863816 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	162	Shared Neighborhood Hits	80
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP8_MOUSE
θ value	3.28125e-26 (rank : 12)	NC score	0.828582 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	362	Shared Neighborhood Hits	74
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP50_MOUSE
θ value	1.05554e-24 (rank : 13)	NC score	0.856474 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP42_HUMAN
θ value	1.29031e-22 (rank : 14)	NC score	0.792549 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	445	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP36_HUMAN
θ value	1.09232e-21 (rank : 15)	NC score	0.815958 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	232	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP20_HUMAN
θ value	1.42661e-21 (rank : 16)	NC score	0.840612 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	113	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP21_MOUSE
θ value	1.86321e-21 (rank : 17)	NC score	0.844907 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP21_HUMAN
θ value	5.42112e-21 (rank : 18)	NC score	0.842943 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP46_HUMAN
θ value	1.74391e-19 (rank : 19)	NC score	0.828996 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	1.74391e-19 (rank : 20)	NC score	0.828996 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP48_MOUSE
θ value	2.97466e-19 (rank : 21)	NC score	0.777151 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP33_HUMAN
θ value	5.07402e-19 (rank : 22)	NC score	0.829925 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP48_HUMAN
θ value	5.07402e-19 (rank : 23)	NC score	0.777249 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP12_HUMAN
θ value	2.5182e-18 (rank : 24)	NC score	0.830652 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP50_HUMAN
θ value	1.24977e-17 (rank : 25)	NC score	0.837509 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP16_HUMAN
θ value	2.13179e-17 (rank : 26)	NC score	0.833487 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP31_HUMAN
θ value	1.38178e-16 (rank : 27)	NC score	0.750405 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	293	Shared Neighborhood Hits	76
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UB17L_HUMAN
θ value	1.80466e-16 (rank : 28)	NC score	0.818232 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBPW_MOUSE
θ value	1.99529e-15 (rank : 29)	NC score	0.826841 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP4_HUMAN
θ value	5.8054e-15 (rank : 30)	NC score	0.741376 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP15_HUMAN
θ value	2.20605e-14 (rank : 31)	NC score	0.742833 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	2.20605e-14 (rank : 32)	NC score	0.743157 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP4_MOUSE
θ value	2.20605e-14 (rank : 33)	NC score	0.740190 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP43_MOUSE
θ value	8.38298e-14 (rank : 34)	NC score	0.751469 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	130	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

USP9X_HUMAN
θ value	8.38298e-14 (rank : 35)	NC score	0.633900 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	161	Shared Neighborhood Hits	74
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP43_HUMAN
θ value	1.86753e-13 (rank : 36)	NC score	0.747398 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

USP9X_MOUSE
θ value	2.43908e-13 (rank : 37)	NC score	0.631254 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	171	Shared Neighborhood Hits	74
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP6_HUMAN
θ value	4.16044e-13 (rank : 38)	NC score	0.623561 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP32_HUMAN
θ value	1.58096e-12 (rank : 39)	NC score	0.657834 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

USP9Y_HUMAN
θ value	2.0648e-12 (rank : 40)	NC score	0.629940 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP11_HUMAN
θ value	3.52202e-12 (rank : 41)	NC score	0.743868 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

BRAP_HUMAN
θ value	7.84624e-12 (rank : 42)	NC score	0.269303 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	560	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	7.84624e-12 (rank : 43)	NC score	0.305367 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

HDAC6_HUMAN
θ value	1.74796e-11 (rank : 44)	NC score	0.211975 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	145	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HDAC6_MOUSE
θ value	4.30538e-10 (rank : 45)	NC score	0.214987 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

UBP34_HUMAN
θ value	2.13673e-09 (rank : 46)	NC score	0.626646 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	210	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	2.13673e-09 (rank : 47)	NC score	0.627599 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	189	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP1_HUMAN
θ value	2.79066e-09 (rank : 48)	NC score	0.716239 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	259	Shared Neighborhood Hits	71
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP10_MOUSE
θ value	3.64472e-09 (rank : 49)	NC score	0.675131 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	150	Shared Neighborhood Hits	70
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP47_MOUSE
θ value	4.76016e-09 (rank : 50)	NC score	0.673464 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	135	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP7_HUMAN
θ value	6.21693e-09 (rank : 51)	NC score	0.697583 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP37_HUMAN
θ value	1.06045e-08 (rank : 52)	NC score	0.603275 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	208	Shared Neighborhood Hits	72
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP47_HUMAN
θ value	2.36244e-08 (rank : 53)	NC score	0.666238 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP18_MOUSE
θ value	3.08544e-08 (rank : 54)	NC score	0.734155 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	77	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP24_HUMAN
θ value	4.0297e-08 (rank : 55)	NC score	0.684201 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP40_HUMAN
θ value	1.17247e-07 (rank : 56)	NC score	0.690663 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP10_HUMAN
θ value	1.53129e-07 (rank : 57)	NC score	0.662203 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	153	Shared Neighborhood Hits	70
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP18_HUMAN
θ value	4.45536e-07 (rank : 58)	NC score	0.743153 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP38_MOUSE
θ value	4.45536e-07 (rank : 59)	NC score	0.612357 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP30_HUMAN
θ value	7.59969e-07 (rank : 60)	NC score	0.703814 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP5_HUMAN
θ value	2.21117e-06 (rank : 61)	NC score	0.522590 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	77
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	2.21117e-06 (rank : 62)	NC score	0.519907 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	106	Shared Neighborhood Hits	77
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP35_HUMAN
θ value	6.43352e-06 (rank : 63)	NC score	0.651094 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	223	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP25_MOUSE
θ value	0.000270298 (rank : 64)	NC score	0.390779 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	116	Shared Neighborhood Hits	73
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP13_HUMAN
θ value	0.00035302 (rank : 65)	NC score	0.514006 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	99	Shared Neighborhood Hits	76
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP38_HUMAN
θ value	0.00035302 (rank : 66)	NC score	0.607324 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP14_HUMAN
θ value	0.000602161 (rank : 67)	NC score	0.593910 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
θ value	0.000602161 (rank : 68)	NC score	0.579569 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP25_HUMAN
θ value	0.000602161 (rank : 69)	NC score	0.387974 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP28_HUMAN
θ value	0.00175202 (rank : 70)	NC score	0.405339 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP26_HUMAN
θ value	0.00390308 (rank : 71)	NC score	0.493823 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP28_MOUSE
θ value	0.00390308 (rank : 72)	NC score	0.398877 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

BCOR_MOUSE
θ value	0.0330416 (rank : 73)	NC score	0.016835 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	521	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

UBP29_HUMAN
θ value	0.0736092 (rank : 74)	NC score	0.501510 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP29_MOUSE
θ value	0.21417 (rank : 75)	NC score	0.482312 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

SNUT2_HUMAN
θ value	0.365318 (rank : 76)	NC score	0.550596 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	79	Shared Neighborhood Hits	61
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	0.365318 (rank : 77)	NC score	0.562240 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	80	Shared Neighborhood Hits	62
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

CI061_MOUSE
θ value	1.06291 (rank : 78)	NC score	0.024363 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q4FZH1	Gene names	Gm967
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf61 homolog.

UBP54_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.085900 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_MOUSE
θ value	1.06291 (rank : 80)	NC score	0.086570 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

CP007_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.018643 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

GOGB1_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.000968 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	2297	Shared Neighborhood Hits	12
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MINT_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.008907 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	1514	Shared Neighborhood Hits	15
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

UBP26_MOUSE
θ value	2.36792 (rank : 84)	NC score	0.397365 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	107	Shared Neighborhood Hits	70
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

DOCK2_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.010418 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

OGFR_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.004599 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	1582	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ZEP2_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.000712 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	937	Shared Neighborhood Hits	5
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

CP007_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.023432 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

ATF6B_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.011607 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

CSKI2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.003298 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

BAIP3_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.004489 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

ITSN1_HUMAN
θ value	6.88961 (rank : 92)	NC score	-0.000399 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	1757	Shared Neighborhood Hits	17
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PKN3_MOUSE
θ value	6.88961 (rank : 93)	NC score	-0.006373 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	1009	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

TRI25_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.004555 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	446	Shared Neighborhood Hits	5
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

ZEP2_MOUSE
θ value	6.88961 (rank : 95)	NC score	-0.000780 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	964	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

CEBPD_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.008162 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

GMEB2_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.009990 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

MKL1_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.011228 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MKL1_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.009740 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	667	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MYO9B_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.001378 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	641	Shared Neighborhood Hits	9
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

GGNB1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.056137 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GGNB1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.074365 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

UBP53_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.052009 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP53_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.050238 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

Hits sorted by NC score

UBP49_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_MOUSE
NC score	0.998001 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP44_HUMAN
NC score	0.992948 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP3_HUMAN
NC score	0.915932 (rank : 4)	θ value	1.36902e-48 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_MOUSE
NC score	0.915592 (rank : 5)	θ value	8.57503e-51 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP22_HUMAN
NC score	0.866243 (rank : 6)	θ value	7.80994e-28 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	87	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
NC score	0.864583 (rank : 7)	θ value	2.68423e-28 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	87	Shared Neighborhood Hits	77
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.863816 (rank : 8)	θ value	3.87602e-27 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	162	Shared Neighborhood Hits	80
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP2_MOUSE
NC score	0.857638 (rank : 9)	θ value	2.19584e-30 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP50_MOUSE
NC score	0.856474 (rank : 10)	θ value	1.05554e-24 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP2_HUMAN
NC score	0.856457 (rank : 11)	θ value	4.89182e-30 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP21_MOUSE
NC score	0.844907 (rank : 12)	θ value	1.86321e-21 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP21_HUMAN
NC score	0.842943 (rank : 13)	θ value	5.42112e-21 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP20_HUMAN
NC score	0.840612 (rank : 14)	θ value	1.42661e-21 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	113	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP50_HUMAN
NC score	0.837509 (rank : 15)	θ value	1.24977e-17 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP16_HUMAN
NC score	0.833487 (rank : 16)	θ value	2.13179e-17 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP12_HUMAN
NC score	0.830652 (rank : 17)	θ value	2.5182e-18 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	85	Shared Neighborhood Hits	75
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP33_HUMAN
NC score	0.829925 (rank : 18)	θ value	5.07402e-19 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP46_HUMAN
NC score	0.828996 (rank : 19)	θ value	1.74391e-19 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.828996 (rank : 20)	θ value	1.74391e-19 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	75
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP8_MOUSE
NC score	0.828582 (rank : 21)	θ value	3.28125e-26 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	362	Shared Neighborhood Hits	74
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBPW_MOUSE
NC score	0.826841 (rank : 22)	θ value	1.99529e-15 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UB17L_HUMAN
NC score	0.818232 (rank : 23)	θ value	1.80466e-16 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP36_HUMAN
NC score	0.815958 (rank : 24)	θ value	1.09232e-21 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	232	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP42_HUMAN
NC score	0.792549 (rank : 25)	θ value	1.29031e-22 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	445	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP8_HUMAN
NC score	0.792215 (rank : 26)	θ value	1.2049e-28 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	751	Shared Neighborhood Hits	76
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP48_HUMAN
NC score	0.777249 (rank : 27)	θ value	5.07402e-19 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.777151 (rank : 28)	θ value	2.97466e-19 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP43_MOUSE
NC score	0.751469 (rank : 29)	θ value	8.38298e-14 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	130	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP31_HUMAN
NC score	0.750405 (rank : 30)	θ value	1.38178e-16 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	293	Shared Neighborhood Hits	76
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP43_HUMAN
NC score	0.747398 (rank : 31)	θ value	1.86753e-13 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP11_HUMAN
NC score	0.743868 (rank : 32)	θ value	3.52202e-12 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP15_MOUSE
NC score	0.743157 (rank : 33)	θ value	2.20605e-14 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP18_HUMAN
NC score	0.743153 (rank : 34)	θ value	4.45536e-07 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP15_HUMAN
NC score	0.742833 (rank : 35)	θ value	2.20605e-14 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP4_HUMAN
NC score	0.741376 (rank : 36)	θ value	5.8054e-15 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
NC score	0.740190 (rank : 37)	θ value	2.20605e-14 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP18_MOUSE
NC score	0.734155 (rank : 38)	θ value	3.08544e-08 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	77	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP1_HUMAN
NC score	0.716239 (rank : 39)	θ value	2.79066e-09 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	259	Shared Neighborhood Hits	71
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP30_HUMAN
NC score	0.703814 (rank : 40)	θ value	7.59969e-07 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP7_HUMAN
NC score	0.697583 (rank : 41)	θ value	6.21693e-09 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP40_HUMAN
NC score	0.690663 (rank : 42)	θ value	1.17247e-07 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP24_HUMAN
NC score	0.684201 (rank : 43)	θ value	4.0297e-08 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP10_MOUSE
NC score	0.675131 (rank : 44)	θ value	3.64472e-09 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	150	Shared Neighborhood Hits	70
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP47_MOUSE
NC score	0.673464 (rank : 45)	θ value	4.76016e-09 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	135	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
NC score	0.666238 (rank : 46)	θ value	2.36244e-08 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP10_HUMAN
NC score	0.662203 (rank : 47)	θ value	1.53129e-07 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	153	Shared Neighborhood Hits	70
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP32_HUMAN
NC score	0.657834 (rank : 48)	θ value	1.58096e-12 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP35_HUMAN
NC score	0.651094 (rank : 49)	θ value	6.43352e-06 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	223	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

USP9X_HUMAN
NC score	0.633900 (rank : 50)	θ value	8.38298e-14 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	161	Shared Neighborhood Hits	74
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.631254 (rank : 51)	θ value	2.43908e-13 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	171	Shared Neighborhood Hits	74
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9Y_HUMAN
NC score	0.629940 (rank : 52)	θ value	2.0648e-12 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP34_MOUSE
NC score	0.627599 (rank : 53)	θ value	2.13673e-09 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	189	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.626646 (rank : 54)	θ value	2.13673e-09 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	210	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP6_HUMAN
NC score	0.623561 (rank : 55)	θ value	4.16044e-13 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP38_MOUSE
NC score	0.612357 (rank : 56)	θ value	4.45536e-07 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP38_HUMAN
NC score	0.607324 (rank : 57)	θ value	0.00035302 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP37_HUMAN
NC score	0.603275 (rank : 58)	θ value	1.06045e-08 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	208	Shared Neighborhood Hits	72
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP14_HUMAN
NC score	0.593910 (rank : 59)	θ value	0.000602161 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
NC score	0.579569 (rank : 60)	θ value	0.000602161 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

SNUT2_MOUSE
NC score	0.562240 (rank : 61)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	80	Shared Neighborhood Hits	62
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
NC score	0.550596 (rank : 62)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	79	Shared Neighborhood Hits	61
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP5_HUMAN
NC score	0.522590 (rank : 63)	θ value	2.21117e-06 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	77
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
NC score	0.519907 (rank : 64)	θ value	2.21117e-06 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	106	Shared Neighborhood Hits	77
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP13_HUMAN
NC score	0.514006 (rank : 65)	θ value	0.00035302 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	99	Shared Neighborhood Hits	76
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP29_HUMAN
NC score	0.501510 (rank : 66)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_HUMAN
NC score	0.493823 (rank : 67)	θ value	0.00390308 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP29_MOUSE
NC score	0.482312 (rank : 68)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP28_HUMAN
NC score	0.405339 (rank : 69)	θ value	0.00175202 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_MOUSE
NC score	0.398877 (rank : 70)	θ value	0.00390308 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP26_MOUSE
NC score	0.397365 (rank : 71)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	107	Shared Neighborhood Hits	70
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP25_MOUSE
NC score	0.390779 (rank : 72)	θ value	0.000270298 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	116	Shared Neighborhood Hits	73
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.387974 (rank : 73)	θ value	0.000602161 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

BRAP_MOUSE
NC score	0.305367 (rank : 74)	θ value	7.84624e-12 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRAP_HUMAN
NC score	0.269303 (rank : 75)	θ value	7.84624e-12 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	560	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

HDAC6_MOUSE
NC score	0.214987 (rank : 76)	θ value	4.30538e-10 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

HDAC6_HUMAN
NC score	0.211975 (rank : 77)	θ value	1.74796e-11 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	145	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

UBP54_MOUSE
NC score	0.086570 (rank : 78)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_HUMAN
NC score	0.085900 (rank : 79)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

GGNB1_MOUSE
NC score	0.074365 (rank : 80)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GGNB1_HUMAN
NC score	0.056137 (rank : 81)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

UBP53_HUMAN
NC score	0.052009 (rank : 82)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP53_MOUSE
NC score	0.050238 (rank : 83)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

CI061_MOUSE
NC score	0.024363 (rank : 84)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q4FZH1	Gene names	Gm967
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf61 homolog.

CP007_HUMAN
NC score	0.023432 (rank : 85)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

CP007_MOUSE
NC score	0.018643 (rank : 86)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

BCOR_MOUSE
NC score	0.016835 (rank : 87)	θ value	0.0330416 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	521	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ATF6B_HUMAN
NC score	0.011607 (rank : 88)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

MKL1_HUMAN
NC score	0.011228 (rank : 89)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

DOCK2_MOUSE
NC score	0.010418 (rank : 90)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

GMEB2_HUMAN
NC score	0.009990 (rank : 91)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

MKL1_MOUSE
NC score	0.009740 (rank : 92)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	667	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MINT_MOUSE
NC score	0.008907 (rank : 93)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	1514	Shared Neighborhood Hits	15
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CEBPD_HUMAN
NC score	0.008162 (rank : 94)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

OGFR_HUMAN
NC score	0.004599 (rank : 95)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	1582	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TRI25_MOUSE
NC score	0.004555 (rank : 96)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	446	Shared Neighborhood Hits	5
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

BAIP3_MOUSE
NC score	0.004489 (rank : 97)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

CSKI2_HUMAN
NC score	0.003298 (rank : 98)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MYO9B_HUMAN
NC score	0.001378 (rank : 99)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	641	Shared Neighborhood Hits	9
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

GOGB1_HUMAN
NC score	0.000968 (rank : 100)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	2297	Shared Neighborhood Hits	12
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

ZEP2_HUMAN
NC score	0.000712 (rank : 101)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	937	Shared Neighborhood Hits	5
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ITSN1_HUMAN
NC score	-0.000399 (rank : 102)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	1757	Shared Neighborhood Hits	17
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ZEP2_MOUSE
NC score	-0.000780 (rank : 103)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	964	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

PKN3_MOUSE
NC score	-0.006373 (rank : 104)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	1009	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).