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Network neighborhood for query Sequence : UBP43_HUMAN

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UBP43_HUMAN
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP31_HUMAN
θ value	0 (rank : 1)	NC score	0.942843 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	293	Shared Neighborhood Hits	84
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP43_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_MOUSE
θ value	0 (rank : 3)	NC score	0.988926 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	130	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP4_HUMAN
θ value	6.81017e-40 (rank : 4)	NC score	0.857166 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
θ value	1.16164e-39 (rank : 5)	NC score	0.856078 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP15_HUMAN
θ value	6.37413e-38 (rank : 6)	NC score	0.854088 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	6.37413e-38 (rank : 7)	NC score	0.854511 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP11_HUMAN
θ value	4.27553e-34 (rank : 8)	NC score	0.855788 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP8_MOUSE
θ value	7.54701e-31 (rank : 9)	NC score	0.832944 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	362	Shared Neighborhood Hits	78
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP8_HUMAN
θ value	1.6813e-30 (rank : 10)	NC score	0.793422 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	751	Shared Neighborhood Hits	81
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP2_MOUSE
θ value	8.63488e-27 (rank : 11)	NC score	0.847069 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_HUMAN
θ value	4.28545e-26 (rank : 12)	NC score	0.844702 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP50_MOUSE
θ value	7.30988e-26 (rank : 13)	NC score	0.842159 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP51_HUMAN
θ value	1.05554e-24 (rank : 14)	NC score	0.811551 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	162	Shared Neighborhood Hits	75
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP33_HUMAN
θ value	2.35151e-24 (rank : 15)	NC score	0.822965 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP6_HUMAN
θ value	3.07116e-24 (rank : 16)	NC score	0.706191 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	79
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP32_HUMAN
θ value	4.01107e-24 (rank : 17)	NC score	0.748745 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	170	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP20_HUMAN
θ value	5.23862e-24 (rank : 18)	NC score	0.824524 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP21_HUMAN
θ value	4.9032e-22 (rank : 19)	NC score	0.828309 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP21_MOUSE
θ value	6.40375e-22 (rank : 20)	NC score	0.829459 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	101	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP3_MOUSE
θ value	8.36355e-22 (rank : 21)	NC score	0.823917 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_HUMAN
θ value	1.86321e-21 (rank : 22)	NC score	0.823572 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP22_HUMAN
θ value	4.15078e-21 (rank : 23)	NC score	0.805200 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
θ value	5.42112e-21 (rank : 24)	NC score	0.806421 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP50_HUMAN
θ value	8.10077e-17 (rank : 25)	NC score	0.826640 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP44_HUMAN
θ value	1.29331e-14 (rank : 26)	NC score	0.761602 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_MOUSE
θ value	1.09485e-13 (rank : 27)	NC score	0.749594 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_HUMAN
θ value	1.86753e-13 (rank : 28)	NC score	0.747398 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP48_MOUSE
θ value	1.74796e-11 (rank : 29)	NC score	0.685486 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_HUMAN
θ value	3.89403e-11 (rank : 30)	NC score	0.686581 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP16_HUMAN
θ value	1.9326e-10 (rank : 31)	NC score	0.773659 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UB17L_HUMAN
θ value	2.52405e-10 (rank : 32)	NC score	0.729411 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP18_MOUSE
θ value	5.62301e-10 (rank : 33)	NC score	0.722212 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP42_HUMAN
θ value	7.34386e-10 (rank : 34)	NC score	0.700149 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	445	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP18_HUMAN
θ value	1.25267e-09 (rank : 35)	NC score	0.735157 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP36_HUMAN
θ value	6.21693e-09 (rank : 36)	NC score	0.712672 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	232	Shared Neighborhood Hits	79
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP46_HUMAN
θ value	6.21693e-09 (rank : 37)	NC score	0.724816 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	6.21693e-09 (rank : 38)	NC score	0.724816 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBPW_MOUSE
θ value	1.06045e-08 (rank : 39)	NC score	0.746092 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP12_HUMAN
θ value	2.36244e-08 (rank : 40)	NC score	0.728510 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP38_MOUSE
θ value	5.26297e-08 (rank : 41)	NC score	0.603811 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP38_HUMAN
θ value	1.53129e-07 (rank : 42)	NC score	0.605754 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP37_HUMAN
θ value	3.41135e-07 (rank : 43)	NC score	0.592203 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

USP9X_MOUSE
θ value	4.45536e-07 (rank : 44)	NC score	0.537326 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	171	Shared Neighborhood Hits	76
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9X_HUMAN
θ value	7.59969e-07 (rank : 45)	NC score	0.537470 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	161	Shared Neighborhood Hits	76
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP24_HUMAN
θ value	1.29631e-06 (rank : 46)	NC score	0.609762 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP35_HUMAN
θ value	2.88788e-06 (rank : 47)	NC score	0.619385 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	223	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP30_HUMAN
θ value	3.77169e-06 (rank : 48)	NC score	0.680168 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP26_HUMAN
θ value	6.43352e-06 (rank : 49)	NC score	0.518552 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP13_HUMAN
θ value	8.40245e-06 (rank : 50)	NC score	0.493576 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

USP9Y_HUMAN
θ value	1.09739e-05 (rank : 51)	NC score	0.533682 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP10_HUMAN
θ value	1.43324e-05 (rank : 52)	NC score	0.610844 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_MOUSE
θ value	1.43324e-05 (rank : 53)	NC score	0.615127 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	150	Shared Neighborhood Hits	71
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP34_HUMAN
θ value	1.87187e-05 (rank : 54)	NC score	0.541928 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	210	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	1.87187e-05 (rank : 55)	NC score	0.541006 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	189	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP47_HUMAN
θ value	2.44474e-05 (rank : 56)	NC score	0.581687 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP29_HUMAN
θ value	3.19293e-05 (rank : 57)	NC score	0.526217 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP14_MOUSE
θ value	7.1131e-05 (rank : 58)	NC score	0.555202 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP40_HUMAN
θ value	7.1131e-05 (rank : 59)	NC score	0.598792 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP14_HUMAN
θ value	9.29e-05 (rank : 60)	NC score	0.566684 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP47_MOUSE
θ value	9.29e-05 (rank : 61)	NC score	0.584702 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	135	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

SNUT2_HUMAN
θ value	0.000121331 (rank : 62)	NC score	0.595447 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	0.000121331 (rank : 63)	NC score	0.601635 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP7_HUMAN
θ value	0.00134147 (rank : 64)	NC score	0.589426 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP5_HUMAN
θ value	0.00228821 (rank : 65)	NC score	0.477255 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	75
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	0.00228821 (rank : 66)	NC score	0.472629 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP28_MOUSE
θ value	0.00298849 (rank : 67)	NC score	0.354022 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	178	Shared Neighborhood Hits	75
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP29_MOUSE
θ value	0.00869519 (rank : 68)	NC score	0.488545 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

CI079_HUMAN
θ value	0.0193708 (rank : 69)	NC score	0.053086 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	288	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

UBP1_HUMAN
θ value	0.0330416 (rank : 70)	NC score	0.608938 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	259	Shared Neighborhood Hits	74
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

CO9A1_MOUSE
θ value	0.0431538 (rank : 71)	NC score	0.035246 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	477	Shared Neighborhood Hits	31
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

COBA2_MOUSE
θ value	0.0431538 (rank : 72)	NC score	0.038724 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	501	Shared Neighborhood Hits	29
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

SPEG_HUMAN
θ value	0.0431538 (rank : 73)	NC score	0.002597 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	1762	Shared Neighborhood Hits	32
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CO5A2_HUMAN
θ value	0.0563607 (rank : 74)	NC score	0.037967 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	760	Shared Neighborhood Hits	33
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

UBP28_HUMAN
θ value	0.0563607 (rank : 75)	NC score	0.349971 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP25_HUMAN
θ value	0.0736092 (rank : 76)	NC score	0.324816 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP25_MOUSE
θ value	0.0736092 (rank : 77)	NC score	0.326257 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	73
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

CO5A3_HUMAN
θ value	0.163984 (rank : 78)	NC score	0.039542 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

TM108_HUMAN
θ value	0.163984 (rank : 79)	NC score	0.033881 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	166	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CAC1H_HUMAN
θ value	0.21417 (rank : 80)	NC score	0.012984 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CSKI2_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.014503 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	747	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

LSD1_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.022396 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	455	Shared Neighborhood Hits	18
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

SDPR_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.018861 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	485	Shared Neighborhood Hits	8
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

CO4A2_MOUSE
θ value	0.62314 (rank : 84)	NC score	0.031798 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

MLL4_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.018948 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	722	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

RGS3_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.024017 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	1621	Shared Neighborhood Hits	49
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CO4A2_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.032870 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	454	Shared Neighborhood Hits	28
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COBA1_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.038178 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	491	Shared Neighborhood Hits	29
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	0.813845 (rank : 89)	NC score	0.038314 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	487	Shared Neighborhood Hits	31
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO4A3_HUMAN
θ value	1.06291 (rank : 90)	NC score	0.033043 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	421	Shared Neighborhood Hits	28
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

UBP26_MOUSE
θ value	1.06291 (rank : 91)	NC score	0.402813 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	107	Shared Neighborhood Hits	70
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

ATS13_HUMAN
θ value	1.38821 (rank : 92)	NC score	0.004950 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	238	Shared Neighborhood Hits	2
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CO2_HUMAN
θ value	1.38821 (rank : 93)	NC score	0.004937 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO7A1_HUMAN
θ value	1.38821 (rank : 94)	NC score	0.024895 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	807	Shared Neighborhood Hits	34
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

PCLO_HUMAN
θ value	1.38821 (rank : 95)	NC score	0.021255 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	2046	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
θ value	1.38821 (rank : 96)	NC score	0.020530 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	2275	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TCF20_MOUSE
θ value	1.38821 (rank : 97)	NC score	0.022771 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	396	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TIF1G_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.009479 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

FIGN_HUMAN
θ value	1.81305 (rank : 99)	NC score	0.007641 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	176	Shared Neighborhood Hits	8
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

MO4L2_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.020092 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

MO4L2_MOUSE
θ value	1.81305 (rank : 101)	NC score	0.020213 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0Q4, Q3UL62, Q6DIB1, Q6ZQK7, Q8C201, Q8C6C2	Gene names	Morf4l2, Kiaa0026, Sid393
Domain Architecture	No domain graphic available
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Sid 393).

OGFR_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.026116 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	1582	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TCGAP_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.014184 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	872	Shared Neighborhood Hits	33
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CO9A1_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.031812 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	420	Shared Neighborhood Hits	29
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

TCOF_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.016653 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TYDP1_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.016885 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJ37, Q8VE39	Gene names	Tdp1
Domain Architecture
Description	Tyrosyl-DNA phosphodiesterase 1 (EC 3.1.4.-) (Tyr-DNA phosphodiesterase 1).

CO3A1_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.038465 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	452	Shared Neighborhood Hits	33
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

EPHB3_HUMAN
θ value	3.0926 (rank : 108)	NC score	-0.002457 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	996	Shared Neighborhood Hits	9
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
θ value	3.0926 (rank : 109)	NC score	-0.002445 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	996	Shared Neighborhood Hits	9
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

LAEVR_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.006953 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).

PACE1_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.012323 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

RAI1_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.019426 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ZN687_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.002472 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	1244	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

DGKG_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.007712 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

ENL_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.033154 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	305	Shared Neighborhood Hits	13
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

RHG06_MOUSE
θ value	4.03905 (rank : 116)	NC score	0.007928 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

ROBO3_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.002815 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	570	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

RP1L1_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.018364 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	1072	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CSKI1_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.006229 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	997	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FOXK1_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.003545 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	215	Shared Neighborhood Hits	8
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

GLDN_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.027853 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	159	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

K0310_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.015283 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	420	Shared Neighborhood Hits	16
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

NIPBL_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.022392 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	1311	Shared Neighborhood Hits	27
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PMS2_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.009388 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

CDKL5_HUMAN
θ value	6.88961 (rank : 125)	NC score	-0.001288 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	967	Shared Neighborhood Hits	14
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CO4A6_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.030322 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	318	Shared Neighborhood Hits	24
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CS007_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.014078 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	401	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

ETV5_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.005984 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

KPBB_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.006156 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q93100, Q8N4T5	Gene names	PHKB
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

LAMP3_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.009884 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQV4, O94781, Q8NEC8	Gene names	LAMP3, DCLAMP, TSC403
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD208 antigen).

MYO9B_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.006987 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	641	Shared Neighborhood Hits	20
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SGIP1_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.021379 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRRM2_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.017236 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	1470	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ZN385_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.030833 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	614	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

BICD2_MOUSE
θ value	8.99809 (rank : 135)	NC score	-0.002853 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	864	Shared Neighborhood Hits	6
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CCD21_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.001143 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	1135	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CT174_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.012236 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

FOXH1_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.004169 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	258	Shared Neighborhood Hits	16
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

MYPT1_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.002491 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	539	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MYSM1_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.006524 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

PDIA5_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.004428 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

SEM6B_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.006345 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

TICN1_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.003597 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TOPB1_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.006561 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

BRAP_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.086556 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	560	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.098251 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

GGNB1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.096275 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GGNB1_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.126792 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

HDAC6_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.062979 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	145	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HDAC6_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.067831 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

TBCD3_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.063071 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

Hits sorted by NC score

UBP43_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_MOUSE
NC score	0.988926 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	130	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP31_HUMAN
NC score	0.942843 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	293	Shared Neighborhood Hits	84
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP4_HUMAN
NC score	0.857166 (rank : 4)	θ value	6.81017e-40 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
NC score	0.856078 (rank : 5)	θ value	1.16164e-39 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP11_HUMAN
NC score	0.855788 (rank : 6)	θ value	4.27553e-34 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP15_MOUSE
NC score	0.854511 (rank : 7)	θ value	6.37413e-38 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP15_HUMAN
NC score	0.854088 (rank : 8)	θ value	6.37413e-38 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP2_MOUSE
NC score	0.847069 (rank : 9)	θ value	8.63488e-27 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_HUMAN
NC score	0.844702 (rank : 10)	θ value	4.28545e-26 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP50_MOUSE
NC score	0.842159 (rank : 11)	θ value	7.30988e-26 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP8_MOUSE
NC score	0.832944 (rank : 12)	θ value	7.54701e-31 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	362	Shared Neighborhood Hits	78
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP21_MOUSE
NC score	0.829459 (rank : 13)	θ value	6.40375e-22 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	101	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP21_HUMAN
NC score	0.828309 (rank : 14)	θ value	4.9032e-22 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP50_HUMAN
NC score	0.826640 (rank : 15)	θ value	8.10077e-17 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP20_HUMAN
NC score	0.824524 (rank : 16)	θ value	5.23862e-24 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP3_MOUSE
NC score	0.823917 (rank : 17)	θ value	8.36355e-22 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_HUMAN
NC score	0.823572 (rank : 18)	θ value	1.86321e-21 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP33_HUMAN
NC score	0.822965 (rank : 19)	θ value	2.35151e-24 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP51_HUMAN
NC score	0.811551 (rank : 20)	θ value	1.05554e-24 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	162	Shared Neighborhood Hits	75
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP22_MOUSE
NC score	0.806421 (rank : 21)	θ value	5.42112e-21 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
NC score	0.805200 (rank : 22)	θ value	4.15078e-21 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP8_HUMAN
NC score	0.793422 (rank : 23)	θ value	1.6813e-30 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	751	Shared Neighborhood Hits	81
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP16_HUMAN
NC score	0.773659 (rank : 24)	θ value	1.9326e-10 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP44_HUMAN
NC score	0.761602 (rank : 25)	θ value	1.29331e-14 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_MOUSE
NC score	0.749594 (rank : 26)	θ value	1.09485e-13 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP32_HUMAN
NC score	0.748745 (rank : 27)	θ value	4.01107e-24 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	170	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP49_HUMAN
NC score	0.747398 (rank : 28)	θ value	1.86753e-13 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBPW_MOUSE
NC score	0.746092 (rank : 29)	θ value	1.06045e-08 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP18_HUMAN
NC score	0.735157 (rank : 30)	θ value	1.25267e-09 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UB17L_HUMAN
NC score	0.729411 (rank : 31)	θ value	2.52405e-10 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP12_HUMAN
NC score	0.728510 (rank : 32)	θ value	2.36244e-08 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP46_HUMAN
NC score	0.724816 (rank : 33)	θ value	6.21693e-09 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.724816 (rank : 34)	θ value	6.21693e-09 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP18_MOUSE
NC score	0.722212 (rank : 35)	θ value	5.62301e-10 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP36_HUMAN
NC score	0.712672 (rank : 36)	θ value	6.21693e-09 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	232	Shared Neighborhood Hits	79
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP6_HUMAN
NC score	0.706191 (rank : 37)	θ value	3.07116e-24 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	79
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP42_HUMAN
NC score	0.700149 (rank : 38)	θ value	7.34386e-10 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	445	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP48_HUMAN
NC score	0.686581 (rank : 39)	θ value	3.89403e-11 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.685486 (rank : 40)	θ value	1.74796e-11 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP30_HUMAN
NC score	0.680168 (rank : 41)	θ value	3.77169e-06 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP35_HUMAN
NC score	0.619385 (rank : 42)	θ value	2.88788e-06 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	223	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP10_MOUSE
NC score	0.615127 (rank : 43)	θ value	1.43324e-05 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	150	Shared Neighborhood Hits	71
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_HUMAN
NC score	0.610844 (rank : 44)	θ value	1.43324e-05 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP24_HUMAN
NC score	0.609762 (rank : 45)	θ value	1.29631e-06 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP1_HUMAN
NC score	0.608938 (rank : 46)	θ value	0.0330416 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	259	Shared Neighborhood Hits	74
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP38_HUMAN
NC score	0.605754 (rank : 47)	θ value	1.53129e-07 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
NC score	0.603811 (rank : 48)	θ value	5.26297e-08 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

SNUT2_MOUSE
NC score	0.601635 (rank : 49)	θ value	0.000121331 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP40_HUMAN
NC score	0.598792 (rank : 50)	θ value	7.1131e-05 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

SNUT2_HUMAN
NC score	0.595447 (rank : 51)	θ value	0.000121331 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP37_HUMAN
NC score	0.592203 (rank : 52)	θ value	3.41135e-07 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP7_HUMAN
NC score	0.589426 (rank : 53)	θ value	0.00134147 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP47_MOUSE
NC score	0.584702 (rank : 54)	θ value	9.29e-05 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	135	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
NC score	0.581687 (rank : 55)	θ value	2.44474e-05 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP14_HUMAN
NC score	0.566684 (rank : 56)	θ value	9.29e-05 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
NC score	0.555202 (rank : 57)	θ value	7.1131e-05 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP34_HUMAN
NC score	0.541928 (rank : 58)	θ value	1.87187e-05 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	210	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
NC score	0.541006 (rank : 59)	θ value	1.87187e-05 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	189	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

USP9X_HUMAN
NC score	0.537470 (rank : 60)	θ value	7.59969e-07 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	161	Shared Neighborhood Hits	76
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.537326 (rank : 61)	θ value	4.45536e-07 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	171	Shared Neighborhood Hits	76
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9Y_HUMAN
NC score	0.533682 (rank : 62)	θ value	1.09739e-05 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP29_HUMAN
NC score	0.526217 (rank : 63)	θ value	3.19293e-05 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_HUMAN
NC score	0.518552 (rank : 64)	θ value	6.43352e-06 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP13_HUMAN
NC score	0.493576 (rank : 65)	θ value	8.40245e-06 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP29_MOUSE
NC score	0.488545 (rank : 66)	θ value	0.00869519 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP5_HUMAN
NC score	0.477255 (rank : 67)	θ value	0.00228821 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	75
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
NC score	0.472629 (rank : 68)	θ value	0.00228821 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP26_MOUSE
NC score	0.402813 (rank : 69)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	107	Shared Neighborhood Hits	70
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP28_MOUSE
NC score	0.354022 (rank : 70)	θ value	0.00298849 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	178	Shared Neighborhood Hits	75
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
NC score	0.349971 (rank : 71)	θ value	0.0563607 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP25_MOUSE
NC score	0.326257 (rank : 72)	θ value	0.0736092 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	73
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.324816 (rank : 73)	θ value	0.0736092 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

GGNB1_MOUSE
NC score	0.126792 (rank : 74)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

BRAP_MOUSE
NC score	0.098251 (rank : 75)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

GGNB1_HUMAN
NC score	0.096275 (rank : 76)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

BRAP_HUMAN
NC score	0.086556 (rank : 77)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	560	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

HDAC6_MOUSE
NC score	0.067831 (rank : 78)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

TBCD3_HUMAN
NC score	0.063071 (rank : 79)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

HDAC6_HUMAN
NC score	0.062979 (rank : 80)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	145	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

CI079_HUMAN
NC score	0.053086 (rank : 81)	θ value	0.0193708 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	288	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CO5A3_HUMAN
NC score	0.039542 (rank : 82)	θ value	0.163984 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	433	Shared Neighborhood Hits	28
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

COBA2_MOUSE
NC score	0.038724 (rank : 83)	θ value	0.0431538 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	501	Shared Neighborhood Hits	29
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CO3A1_HUMAN
NC score	0.038465 (rank : 84)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	452	Shared Neighborhood Hits	33
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COBA1_MOUSE
NC score	0.038314 (rank : 85)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	487	Shared Neighborhood Hits	31
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_HUMAN
NC score	0.038178 (rank : 86)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	491	Shared Neighborhood Hits	29
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO5A2_HUMAN
NC score	0.037967 (rank : 87)	θ value	0.0563607 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	760	Shared Neighborhood Hits	33
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO9A1_MOUSE
NC score	0.035246 (rank : 88)	θ value	0.0431538 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	477	Shared Neighborhood Hits	31
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

TM108_HUMAN
NC score	0.033881 (rank : 89)	θ value	0.163984 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	166	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ENL_HUMAN
NC score	0.033154 (rank : 90)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	305	Shared Neighborhood Hits	13
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

CO4A3_HUMAN
NC score	0.033043 (rank : 91)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	421	Shared Neighborhood Hits	28
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO4A2_HUMAN
NC score	0.032870 (rank : 92)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	454	Shared Neighborhood Hits	28
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO9A1_HUMAN
NC score	0.031812 (rank : 93)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	420	Shared Neighborhood Hits	29
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO4A2_MOUSE
NC score	0.031798 (rank : 94)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	492	Shared Neighborhood Hits	27
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

ZN385_HUMAN
NC score	0.030833 (rank : 95)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	614	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CO4A6_HUMAN
NC score	0.030322 (rank : 96)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	318	Shared Neighborhood Hits	24
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

GLDN_HUMAN
NC score	0.027853 (rank : 97)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	159	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZMI3, Q6UXZ7, Q7Z359	Gene names	GLDN, COLM
Domain Architecture	No domain graphic available
Description	Gliomedin.

OGFR_HUMAN
NC score	0.026116 (rank : 98)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	1582	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CO7A1_HUMAN
NC score	0.024895 (rank : 99)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	807	Shared Neighborhood Hits	34
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

RGS3_MOUSE
NC score	0.024017 (rank : 100)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	1621	Shared Neighborhood Hits	49
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TCF20_MOUSE
NC score	0.022771 (rank : 101)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	396	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

LSD1_HUMAN
NC score	0.022396 (rank : 102)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	455	Shared Neighborhood Hits	18
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

NIPBL_HUMAN
NC score	0.022392 (rank : 103)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	1311	Shared Neighborhood Hits	27
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SGIP1_HUMAN
NC score	0.021379 (rank : 104)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

PCLO_HUMAN
NC score	0.021255 (rank : 105)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	2046	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
NC score	0.020530 (rank : 106)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	2275	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MO4L2_MOUSE
NC score	0.020213 (rank : 107)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0Q4, Q3UL62, Q6DIB1, Q6ZQK7, Q8C201, Q8C6C2	Gene names	Morf4l2, Kiaa0026, Sid393
Domain Architecture	No domain graphic available
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Sid 393).

MO4L2_HUMAN
NC score	0.020092 (rank : 108)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

RAI1_MOUSE
NC score	0.019426 (rank : 109)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

MLL4_HUMAN
NC score	0.018948 (rank : 110)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	722	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SDPR_MOUSE
NC score	0.018861 (rank : 111)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	485	Shared Neighborhood Hits	8
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

RP1L1_HUMAN
NC score	0.018364 (rank : 112)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	1072	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SRRM2_MOUSE
NC score	0.017236 (rank : 113)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	1470	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TYDP1_MOUSE
NC score	0.016885 (rank : 114)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJ37, Q8VE39	Gene names	Tdp1
Domain Architecture
Description	Tyrosyl-DNA phosphodiesterase 1 (EC 3.1.4.-) (Tyr-DNA phosphodiesterase 1).

TCOF_MOUSE
NC score	0.016653 (rank : 115)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

K0310_HUMAN
NC score	0.015283 (rank : 116)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	420	Shared Neighborhood Hits	16
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

CSKI2_HUMAN
NC score	0.014503 (rank : 117)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	747	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TCGAP_HUMAN
NC score	0.014184 (rank : 118)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	872	Shared Neighborhood Hits	33
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CS007_HUMAN
NC score	0.014078 (rank : 119)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	401	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CAC1H_HUMAN
NC score	0.012984 (rank : 120)	θ value	0.21417 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

PACE1_MOUSE
NC score	0.012323 (rank : 121)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

CT174_HUMAN
NC score	0.012236 (rank : 122)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

LAMP3_HUMAN
NC score	0.009884 (rank : 123)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQV4, O94781, Q8NEC8	Gene names	LAMP3, DCLAMP, TSC403
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD208 antigen).

TIF1G_MOUSE
NC score	0.009479 (rank : 124)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

PMS2_MOUSE
NC score	0.009388 (rank : 125)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

RHG06_MOUSE
NC score	0.007928 (rank : 126)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

DGKG_MOUSE
NC score	0.007712 (rank : 127)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

FIGN_HUMAN
NC score	0.007641 (rank : 128)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	176	Shared Neighborhood Hits	8
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

MYO9B_HUMAN
NC score	0.006987 (rank : 129)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	641	Shared Neighborhood Hits	20
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

LAEVR_HUMAN
NC score	0.006953 (rank : 130)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).

TOPB1_MOUSE
NC score	0.006561 (rank : 131)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

MYSM1_HUMAN
NC score	0.006524 (rank : 132)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

SEM6B_HUMAN
NC score	0.006345 (rank : 133)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

CSKI1_HUMAN
NC score	0.006229 (rank : 134)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	997	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

KPBB_HUMAN
NC score	0.006156 (rank : 135)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q93100, Q8N4T5	Gene names	PHKB
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

ETV5_MOUSE
NC score	0.005984 (rank : 136)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

ATS13_HUMAN
NC score	0.004950 (rank : 137)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	238	Shared Neighborhood Hits	2
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CO2_HUMAN
NC score	0.004937 (rank : 138)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

PDIA5_MOUSE
NC score	0.004428 (rank : 139)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

FOXH1_HUMAN
NC score	0.004169 (rank : 140)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	258	Shared Neighborhood Hits	16
SwissProt Accessions	O75593	Gene names	FOXH1, FAST1, FAST2
Domain Architecture
Description	Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast- 1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2).

TICN1_MOUSE
NC score	0.003597 (rank : 141)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

FOXK1_MOUSE
NC score	0.003545 (rank : 142)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	215	Shared Neighborhood Hits	8
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

ROBO3_HUMAN
NC score	0.002815 (rank : 143)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	570	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

SPEG_HUMAN
NC score	0.002597 (rank : 144)	θ value	0.0431538 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	1762	Shared Neighborhood Hits	32
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MYPT1_MOUSE
NC score	0.002491 (rank : 145)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	539	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ZN687_HUMAN
NC score	0.002472 (rank : 146)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	1244	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CCD21_MOUSE
NC score	0.001143 (rank : 147)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	1135	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CDKL5_HUMAN
NC score	-0.001288 (rank : 148)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	967	Shared Neighborhood Hits	14
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

EPHB3_MOUSE
NC score	-0.002445 (rank : 149)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	996	Shared Neighborhood Hits	9
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB3_HUMAN
NC score	-0.002457 (rank : 150)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	996	Shared Neighborhood Hits	9
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

BICD2_MOUSE
NC score	-0.002853 (rank : 151)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	864	Shared Neighborhood Hits	6
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.