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Network neighborhood for query Sequence : UBP31_HUMAN

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UBP31_HUMAN
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP31_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	293	Target Neighborhood Hits	293	Shared Neighborhood Hits	293
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP43_HUMAN
θ value	0 (rank : 2)	NC score	0.942843 (rank : 3)
Query Neighborhood Hits	293	Target Neighborhood Hits	144	Shared Neighborhood Hits	84
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_MOUSE
θ value	0 (rank : 3)	NC score	0.944435 (rank : 2)
Query Neighborhood Hits	293	Target Neighborhood Hits	130	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP15_HUMAN
θ value	1.51715e-39 (rank : 4)	NC score	0.839711 (rank : 7)
Query Neighborhood Hits	293	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	2.58786e-39 (rank : 5)	NC score	0.839926 (rank : 6)
Query Neighborhood Hits	293	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP4_HUMAN
θ value	3.37985e-39 (rank : 6)	NC score	0.841695 (rank : 4)
Query Neighborhood Hits	293	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
θ value	7.52953e-39 (rank : 7)	NC score	0.840470 (rank : 5)
Query Neighborhood Hits	293	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP11_HUMAN
θ value	8.91499e-32 (rank : 8)	NC score	0.838468 (rank : 8)
Query Neighborhood Hits	293	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP8_HUMAN
θ value	3.74554e-30 (rank : 9)	NC score	0.791829 (rank : 23)
Query Neighborhood Hits	293	Target Neighborhood Hits	751	Shared Neighborhood Hits	107
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP8_MOUSE
θ value	3.74554e-30 (rank : 10)	NC score	0.824387 (rank : 12)
Query Neighborhood Hits	293	Target Neighborhood Hits	362	Shared Neighborhood Hits	91
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP33_HUMAN
θ value	1.92365e-26 (rank : 11)	NC score	0.816883 (rank : 14)
Query Neighborhood Hits	293	Target Neighborhood Hits	157	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP20_HUMAN
θ value	7.30988e-26 (rank : 12)	NC score	0.819789 (rank : 13)
Query Neighborhood Hits	293	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP50_MOUSE
θ value	1.62847e-25 (rank : 13)	NC score	0.828605 (rank : 11)
Query Neighborhood Hits	293	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP2_MOUSE
θ value	6.18819e-25 (rank : 14)	NC score	0.833747 (rank : 9)
Query Neighborhood Hits	293	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_HUMAN
θ value	4.01107e-24 (rank : 15)	NC score	0.831888 (rank : 10)
Query Neighborhood Hits	293	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP51_HUMAN
θ value	3.75424e-22 (rank : 16)	NC score	0.801915 (rank : 20)
Query Neighborhood Hits	293	Target Neighborhood Hits	162	Shared Neighborhood Hits	87
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP32_HUMAN
θ value	1.86321e-21 (rank : 17)	NC score	0.727519 (rank : 33)
Query Neighborhood Hits	293	Target Neighborhood Hits	170	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP6_HUMAN
θ value	3.17815e-21 (rank : 18)	NC score	0.686880 (rank : 40)
Query Neighborhood Hits	293	Target Neighborhood Hits	188	Shared Neighborhood Hits	81
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP3_HUMAN
θ value	4.15078e-21 (rank : 19)	NC score	0.814461 (rank : 16)
Query Neighborhood Hits	293	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_MOUSE
θ value	1.2077e-20 (rank : 20)	NC score	0.813103 (rank : 19)
Query Neighborhood Hits	293	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP22_MOUSE
θ value	2.06002e-20 (rank : 21)	NC score	0.794902 (rank : 21)
Query Neighborhood Hits	293	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
θ value	3.51386e-20 (rank : 22)	NC score	0.793804 (rank : 22)
Query Neighborhood Hits	293	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP21_HUMAN
θ value	1.74391e-19 (rank : 23)	NC score	0.813773 (rank : 18)
Query Neighborhood Hits	293	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP21_MOUSE
θ value	1.74391e-19 (rank : 24)	NC score	0.815158 (rank : 15)
Query Neighborhood Hits	293	Target Neighborhood Hits	101	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP50_HUMAN
θ value	2.7842e-17 (rank : 25)	NC score	0.814456 (rank : 17)
Query Neighborhood Hits	293	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP49_MOUSE
θ value	6.20254e-17 (rank : 26)	NC score	0.751879 (rank : 26)
Query Neighborhood Hits	293	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP44_HUMAN
θ value	1.38178e-16 (rank : 27)	NC score	0.762764 (rank : 25)
Query Neighborhood Hits	293	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_HUMAN
θ value	1.38178e-16 (rank : 28)	NC score	0.750405 (rank : 27)
Query Neighborhood Hits	293	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP18_MOUSE
θ value	2.88119e-14 (rank : 29)	NC score	0.732143 (rank : 30)
Query Neighborhood Hits	293	Target Neighborhood Hits	77	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP18_HUMAN
θ value	3.76295e-14 (rank : 30)	NC score	0.744073 (rank : 29)
Query Neighborhood Hits	293	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP16_HUMAN
θ value	5.43371e-13 (rank : 31)	NC score	0.769781 (rank : 24)
Query Neighborhood Hits	293	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBPW_MOUSE
θ value	7.84624e-12 (rank : 32)	NC score	0.744523 (rank : 28)
Query Neighborhood Hits	293	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP48_HUMAN
θ value	1.33837e-11 (rank : 33)	NC score	0.689285 (rank : 38)
Query Neighborhood Hits	293	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
θ value	1.33837e-11 (rank : 34)	NC score	0.688163 (rank : 39)
Query Neighborhood Hits	293	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UB17L_HUMAN
θ value	8.67504e-11 (rank : 35)	NC score	0.727963 (rank : 31)
Query Neighborhood Hits	293	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP42_HUMAN
θ value	1.47974e-10 (rank : 36)	NC score	0.714190 (rank : 37)
Query Neighborhood Hits	293	Target Neighborhood Hits	445	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP36_HUMAN
θ value	2.52405e-10 (rank : 37)	NC score	0.727578 (rank : 32)
Query Neighborhood Hits	293	Target Neighborhood Hits	232	Shared Neighborhood Hits	103
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

USP9X_HUMAN
θ value	1.80886e-08 (rank : 38)	NC score	0.550858 (rank : 58)
Query Neighborhood Hits	293	Target Neighborhood Hits	161	Shared Neighborhood Hits	76
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	1.80886e-08 (rank : 39)	NC score	0.549709 (rank : 59)
Query Neighborhood Hits	293	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP46_HUMAN
θ value	3.08544e-08 (rank : 40)	NC score	0.718197 (rank : 35)
Query Neighborhood Hits	293	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	3.08544e-08 (rank : 41)	NC score	0.718197 (rank : 36)
Query Neighborhood Hits	293	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP12_HUMAN
θ value	5.26297e-08 (rank : 42)	NC score	0.721825 (rank : 34)
Query Neighborhood Hits	293	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP34_HUMAN
θ value	5.26297e-08 (rank : 43)	NC score	0.560063 (rank : 56)
Query Neighborhood Hits	293	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP24_HUMAN
θ value	8.97725e-08 (rank : 44)	NC score	0.619293 (rank : 43)
Query Neighborhood Hits	293	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP34_MOUSE
θ value	1.53129e-07 (rank : 45)	NC score	0.559127 (rank : 57)
Query Neighborhood Hits	293	Target Neighborhood Hits	189	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

USP9Y_HUMAN
θ value	2.61198e-07 (rank : 46)	NC score	0.546470 (rank : 60)
Query Neighborhood Hits	293	Target Neighborhood Hits	109	Shared Neighborhood Hits	75
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP30_HUMAN
θ value	7.59969e-07 (rank : 47)	NC score	0.669187 (rank : 41)
Query Neighborhood Hits	293	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

NFH_MOUSE
θ value	1.69304e-06 (rank : 48)	NC score	0.063459 (rank : 134)
Query Neighborhood Hits	293	Target Neighborhood Hits	2247	Shared Neighborhood Hits	139
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

UBP35_HUMAN
θ value	3.77169e-06 (rank : 49)	NC score	0.613046 (rank : 44)
Query Neighborhood Hits	293	Target Neighborhood Hits	223	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP47_HUMAN
θ value	3.77169e-06 (rank : 50)	NC score	0.589904 (rank : 51)
Query Neighborhood Hits	293	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP7_HUMAN
θ value	4.92598e-06 (rank : 51)	NC score	0.604922 (rank : 47)
Query Neighborhood Hits	293	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

INVS_MOUSE
θ value	6.43352e-06 (rank : 52)	NC score	0.034252 (rank : 228)
Query Neighborhood Hits	293	Target Neighborhood Hits	609	Shared Neighborhood Hits	46
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

UBP38_HUMAN
θ value	6.43352e-06 (rank : 53)	NC score	0.586727 (rank : 52)
Query Neighborhood Hits	293	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP13_HUMAN
θ value	8.40245e-06 (rank : 54)	NC score	0.489518 (rank : 64)
Query Neighborhood Hits	293	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

TGON2_HUMAN
θ value	1.09739e-05 (rank : 55)	NC score	0.102184 (rank : 85)
Query Neighborhood Hits	293	Target Neighborhood Hits	1037	Shared Neighborhood Hits	96
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

UBP38_MOUSE
θ value	1.09739e-05 (rank : 56)	NC score	0.584236 (rank : 53)
Query Neighborhood Hits	293	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP10_HUMAN
θ value	1.43324e-05 (rank : 57)	NC score	0.603688 (rank : 48)
Query Neighborhood Hits	293	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP26_HUMAN
θ value	1.87187e-05 (rank : 58)	NC score	0.488371 (rank : 65)
Query Neighborhood Hits	293	Target Neighborhood Hits	108	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

NPBL_MOUSE
θ value	2.44474e-05 (rank : 59)	NC score	0.106707 (rank : 81)
Query Neighborhood Hits	293	Target Neighborhood Hits	1041	Shared Neighborhood Hits	92
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

UBP47_MOUSE
θ value	2.44474e-05 (rank : 60)	NC score	0.592553 (rank : 49)
Query Neighborhood Hits	293	Target Neighborhood Hits	135	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP37_HUMAN
θ value	3.19293e-05 (rank : 61)	NC score	0.566451 (rank : 55)
Query Neighborhood Hits	293	Target Neighborhood Hits	208	Shared Neighborhood Hits	77
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP5_HUMAN
θ value	7.1131e-05 (rank : 62)	NC score	0.479613 (rank : 66)
Query Neighborhood Hits	293	Target Neighborhood Hits	109	Shared Neighborhood Hits	74
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP40_HUMAN
θ value	9.29e-05 (rank : 63)	NC score	0.608074 (rank : 45)
Query Neighborhood Hits	293	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

NIPBL_HUMAN
θ value	0.000121331 (rank : 64)	NC score	0.098977 (rank : 87)
Query Neighborhood Hits	293	Target Neighborhood Hits	1311	Shared Neighborhood Hits	103
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

UBP1_HUMAN
θ value	0.000121331 (rank : 65)	NC score	0.627059 (rank : 42)
Query Neighborhood Hits	293	Target Neighborhood Hits	259	Shared Neighborhood Hits	88
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

LAD1_HUMAN
θ value	0.000158464 (rank : 66)	NC score	0.117469 (rank : 76)
Query Neighborhood Hits	293	Target Neighborhood Hits	441	Shared Neighborhood Hits	54
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

UBP10_MOUSE
θ value	0.00020696 (rank : 67)	NC score	0.607191 (rank : 46)
Query Neighborhood Hits	293	Target Neighborhood Hits	150	Shared Neighborhood Hits	82
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP5_MOUSE
θ value	0.00020696 (rank : 68)	NC score	0.474870 (rank : 67)
Query Neighborhood Hits	293	Target Neighborhood Hits	106	Shared Neighborhood Hits	74
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

TXND2_MOUSE
θ value	0.000461057 (rank : 69)	NC score	0.078733 (rank : 102)
Query Neighborhood Hits	293	Target Neighborhood Hits	828	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

SNUT2_HUMAN
θ value	0.000786445 (rank : 70)	NC score	0.583890 (rank : 54)
Query Neighborhood Hits	293	Target Neighborhood Hits	79	Shared Neighborhood Hits	62
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	0.000786445 (rank : 71)	NC score	0.590308 (rank : 50)
Query Neighborhood Hits	293	Target Neighborhood Hits	80	Shared Neighborhood Hits	62
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

LAD1_MOUSE
θ value	0.00102713 (rank : 72)	NC score	0.105243 (rank : 82)
Query Neighborhood Hits	293	Target Neighborhood Hits	391	Shared Neighborhood Hits	52
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

NACAM_MOUSE
θ value	0.00228821 (rank : 73)	NC score	0.087566 (rank : 96)
Query Neighborhood Hits	293	Target Neighborhood Hits	1866	Shared Neighborhood Hits	136
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PDZD2_HUMAN
θ value	0.00228821 (rank : 74)	NC score	0.064716 (rank : 129)
Query Neighborhood Hits	293	Target Neighborhood Hits	772	Shared Neighborhood Hits	81
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

UBP29_HUMAN
θ value	0.00228821 (rank : 75)	NC score	0.495323 (rank : 63)
Query Neighborhood Hits	293	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

MDC1_HUMAN
θ value	0.00298849 (rank : 76)	NC score	0.098015 (rank : 88)
Query Neighborhood Hits	293	Target Neighborhood Hits	1446	Shared Neighborhood Hits	113
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TARA_HUMAN
θ value	0.00390308 (rank : 77)	NC score	0.071443 (rank : 113)
Query Neighborhood Hits	293	Target Neighborhood Hits	1626	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RBBP6_HUMAN
θ value	0.00509761 (rank : 78)	NC score	0.071087 (rank : 115)
Query Neighborhood Hits	293	Target Neighborhood Hits	1135	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RGS3_MOUSE
θ value	0.00509761 (rank : 79)	NC score	0.053829 (rank : 173)
Query Neighborhood Hits	293	Target Neighborhood Hits	1621	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MUC5B_HUMAN
θ value	0.00665767 (rank : 80)	NC score	0.049361 (rank : 199)
Query Neighborhood Hits	293	Target Neighborhood Hits	1020	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CDKL5_HUMAN
θ value	0.00869519 (rank : 81)	NC score	0.007348 (rank : 334)
Query Neighborhood Hits	293	Target Neighborhood Hits	967	Shared Neighborhood Hits	38
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

MAP4_MOUSE
θ value	0.00869519 (rank : 82)	NC score	0.087680 (rank : 95)
Query Neighborhood Hits	293	Target Neighborhood Hits	409	Shared Neighborhood Hits	72
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

DACT1_MOUSE
θ value	0.0113563 (rank : 83)	NC score	0.071377 (rank : 114)
Query Neighborhood Hits	293	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

JARD2_MOUSE
θ value	0.0252991 (rank : 84)	NC score	0.045419 (rank : 203)
Query Neighborhood Hits	293	Target Neighborhood Hits	169	Shared Neighborhood Hits	24
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

NOL8_HUMAN
θ value	0.0252991 (rank : 85)	NC score	0.053815 (rank : 174)
Query Neighborhood Hits	293	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

AHTF1_MOUSE
θ value	0.0330416 (rank : 86)	NC score	0.050840 (rank : 193)
Query Neighborhood Hits	293	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CARD6_HUMAN
θ value	0.0330416 (rank : 87)	NC score	0.066707 (rank : 125)
Query Neighborhood Hits	293	Target Neighborhood Hits	145	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

ESPL1_MOUSE
θ value	0.0330416 (rank : 88)	NC score	0.039537 (rank : 215)
Query Neighborhood Hits	293	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

MBB1A_HUMAN
θ value	0.0330416 (rank : 89)	NC score	0.062947 (rank : 136)
Query Neighborhood Hits	293	Target Neighborhood Hits	665	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MDC1_MOUSE
θ value	0.0431538 (rank : 90)	NC score	0.081729 (rank : 99)
Query Neighborhood Hits	293	Target Neighborhood Hits	998	Shared Neighborhood Hits	88
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

DACT1_HUMAN
θ value	0.0736092 (rank : 91)	NC score	0.074970 (rank : 106)
Query Neighborhood Hits	293	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

GRIN1_HUMAN
θ value	0.0736092 (rank : 92)	NC score	0.067867 (rank : 122)
Query Neighborhood Hits	293	Target Neighborhood Hits	681	Shared Neighborhood Hits	72
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

UBP28_MOUSE
θ value	0.0736092 (rank : 93)	NC score	0.339327 (rank : 70)
Query Neighborhood Hits	293	Target Neighborhood Hits	178	Shared Neighborhood Hits	78
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ANK2_HUMAN
θ value	0.0961366 (rank : 94)	NC score	0.035507 (rank : 222)
Query Neighborhood Hits	293	Target Neighborhood Hits	1615	Shared Neighborhood Hits	106
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BRWD1_MOUSE
θ value	0.0961366 (rank : 95)	NC score	0.014938 (rank : 304)
Query Neighborhood Hits	293	Target Neighborhood Hits	478	Shared Neighborhood Hits	26
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

RIF1_HUMAN
θ value	0.0961366 (rank : 96)	NC score	0.040367 (rank : 212)
Query Neighborhood Hits	293	Target Neighborhood Hits	320	Shared Neighborhood Hits	29
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

UBP28_HUMAN
θ value	0.0961366 (rank : 97)	NC score	0.338152 (rank : 71)
Query Neighborhood Hits	293	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

BSN_HUMAN
θ value	0.125558 (rank : 98)	NC score	0.076986 (rank : 105)
Query Neighborhood Hits	293	Target Neighborhood Hits	1537	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

COA2_HUMAN
θ value	0.125558 (rank : 99)	NC score	0.032601 (rank : 236)
Query Neighborhood Hits	293	Target Neighborhood Hits	184	Shared Neighborhood Hits	26
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

MARK2_MOUSE
θ value	0.125558 (rank : 100)	NC score	0.005578 (rank : 349)
Query Neighborhood Hits	293	Target Neighborhood Hits	1018	Shared Neighborhood Hits	48
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

MYCB2_HUMAN
θ value	0.125558 (rank : 101)	NC score	0.044645 (rank : 206)
Query Neighborhood Hits	293	Target Neighborhood Hits	390	Shared Neighborhood Hits	44
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PCLO_HUMAN
θ value	0.125558 (rank : 102)	NC score	0.079114 (rank : 100)
Query Neighborhood Hits	293	Target Neighborhood Hits	2046	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

BARH1_HUMAN
θ value	0.163984 (rank : 103)	NC score	0.009306 (rank : 325)
Query Neighborhood Hits	293	Target Neighborhood Hits	373	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BZE3, Q9NY88	Gene names	BARHL1
Domain Architecture
Description	BarH-like 1 homeobox protein.

DAB2_HUMAN
θ value	0.163984 (rank : 104)	NC score	0.041310 (rank : 210)
Query Neighborhood Hits	293	Target Neighborhood Hits	197	Shared Neighborhood Hits	25
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

GA2L2_MOUSE
θ value	0.163984 (rank : 105)	NC score	0.039158 (rank : 216)
Query Neighborhood Hits	293	Target Neighborhood Hits	395	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

JHD2C_MOUSE
θ value	0.163984 (rank : 106)	NC score	0.034526 (rank : 226)
Query Neighborhood Hits	293	Target Neighborhood Hits	297	Shared Neighborhood Hits	37
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

IWS1_HUMAN
θ value	0.21417 (rank : 107)	NC score	0.064168 (rank : 132)
Query Neighborhood Hits	293	Target Neighborhood Hits	1241	Shared Neighborhood Hits	91
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K0323_HUMAN
θ value	0.21417 (rank : 108)	NC score	0.033657 (rank : 232)
Query Neighborhood Hits	293	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

K0423_HUMAN
θ value	0.21417 (rank : 109)	NC score	0.034901 (rank : 224)
Query Neighborhood Hits	293	Target Neighborhood Hits	171	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

LYRIC_MOUSE
θ value	0.21417 (rank : 110)	NC score	0.051068 (rank : 191)
Query Neighborhood Hits	293	Target Neighborhood Hits	126	Shared Neighborhood Hits	23
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

RRBP1_MOUSE
θ value	0.21417 (rank : 111)	NC score	0.026673 (rank : 251)
Query Neighborhood Hits	293	Target Neighborhood Hits	1650	Shared Neighborhood Hits	71
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ZN473_MOUSE
θ value	0.21417 (rank : 112)	NC score	-0.004942 (rank : 368)
Query Neighborhood Hits	293	Target Neighborhood Hits	824	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BI67, Q8BI98, Q8BIB7	Gene names	Znf473, Zfp100, Zfp473
Domain Architecture	No domain graphic available
Description	Zinc finger protein 473 homolog (Zinc finger protein 100) (Zfp-100).

GP124_MOUSE
θ value	0.279714 (rank : 113)	NC score	0.010132 (rank : 320)
Query Neighborhood Hits	293	Target Neighborhood Hits	423	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

MCM4_HUMAN
θ value	0.279714 (rank : 114)	NC score	0.015485 (rank : 301)
Query Neighborhood Hits	293	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MPDZ_HUMAN
θ value	0.279714 (rank : 115)	NC score	0.016926 (rank : 292)
Query Neighborhood Hits	293	Target Neighborhood Hits	261	Shared Neighborhood Hits	16
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

SRRM1_MOUSE
θ value	0.279714 (rank : 116)	NC score	0.114531 (rank : 77)
Query Neighborhood Hits	293	Target Neighborhood Hits	966	Shared Neighborhood Hits	123
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TBX3_HUMAN
θ value	0.279714 (rank : 117)	NC score	0.017641 (rank : 289)
Query Neighborhood Hits	293	Target Neighborhood Hits	121	Shared Neighborhood Hits	16
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

UBP14_HUMAN
θ value	0.279714 (rank : 118)	NC score	0.532590 (rank : 61)
Query Neighborhood Hits	293	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
θ value	0.279714 (rank : 119)	NC score	0.519667 (rank : 62)
Query Neighborhood Hits	293	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

CC14A_HUMAN
θ value	0.365318 (rank : 120)	NC score	0.020848 (rank : 269)
Query Neighborhood Hits	293	Target Neighborhood Hits	133	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CJ012_HUMAN
θ value	0.365318 (rank : 121)	NC score	0.078709 (rank : 103)
Query Neighborhood Hits	293	Target Neighborhood Hits	467	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

M3K3_MOUSE
θ value	0.365318 (rank : 122)	NC score	0.001958 (rank : 358)
Query Neighborhood Hits	293	Target Neighborhood Hits	876	Shared Neighborhood Hits	26
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MUC1_HUMAN
θ value	0.365318 (rank : 123)	NC score	0.045309 (rank : 204)
Query Neighborhood Hits	293	Target Neighborhood Hits	975	Shared Neighborhood Hits	65
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC1_MOUSE
θ value	0.365318 (rank : 124)	NC score	0.078740 (rank : 101)
Query Neighborhood Hits	293	Target Neighborhood Hits	388	Shared Neighborhood Hits	57
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MYO9B_HUMAN
θ value	0.365318 (rank : 125)	NC score	0.019894 (rank : 278)
Query Neighborhood Hits	293	Target Neighborhood Hits	641	Shared Neighborhood Hits	60
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TTC28_HUMAN
θ value	0.365318 (rank : 126)	NC score	0.029173 (rank : 245)
Query Neighborhood Hits	293	Target Neighborhood Hits	271	Shared Neighborhood Hits	31
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TIP60_MOUSE
θ value	0.47712 (rank : 127)	NC score	0.026649 (rank : 252)
Query Neighborhood Hits	293	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TXND2_HUMAN
θ value	0.47712 (rank : 128)	NC score	0.069764 (rank : 120)
Query Neighborhood Hits	293	Target Neighborhood Hits	793	Shared Neighborhood Hits	77
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BSN_MOUSE
θ value	0.62314 (rank : 129)	NC score	0.069900 (rank : 118)
Query Neighborhood Hits	293	Target Neighborhood Hits	2057	Shared Neighborhood Hits	134
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

COHA1_MOUSE
θ value	0.62314 (rank : 130)	NC score	0.024402 (rank : 256)
Query Neighborhood Hits	293	Target Neighborhood Hits	414	Shared Neighborhood Hits	40
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DAB2_MOUSE
θ value	0.62314 (rank : 131)	NC score	0.040168 (rank : 213)
Query Neighborhood Hits	293	Target Neighborhood Hits	163	Shared Neighborhood Hits	24
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

NALP5_MOUSE
θ value	0.62314 (rank : 132)	NC score	0.023588 (rank : 262)
Query Neighborhood Hits	293	Target Neighborhood Hits	560	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

SON_HUMAN
θ value	0.62314 (rank : 133)	NC score	0.050740 (rank : 194)
Query Neighborhood Hits	293	Target Neighborhood Hits	1568	Shared Neighborhood Hits	98
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TIP60_HUMAN
θ value	0.62314 (rank : 134)	NC score	0.025841 (rank : 254)
Query Neighborhood Hits	293	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

UBP25_HUMAN
θ value	0.62314 (rank : 135)	NC score	0.310829 (rank : 73)
Query Neighborhood Hits	293	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP25_MOUSE
θ value	0.62314 (rank : 136)	NC score	0.312618 (rank : 72)
Query Neighborhood Hits	293	Target Neighborhood Hits	116	Shared Neighborhood Hits	73
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

BAT2_HUMAN
θ value	0.813845 (rank : 137)	NC score	0.072526 (rank : 111)
Query Neighborhood Hits	293	Target Neighborhood Hits	931	Shared Neighborhood Hits	90
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CENPT_MOUSE
θ value	0.813845 (rank : 138)	NC score	0.045166 (rank : 205)
Query Neighborhood Hits	293	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

IRF7_HUMAN
θ value	0.813845 (rank : 139)	NC score	0.017394 (rank : 290)
Query Neighborhood Hits	293	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

LIPB2_MOUSE
θ value	0.813845 (rank : 140)	NC score	0.009645 (rank : 324)
Query Neighborhood Hits	293	Target Neighborhood Hits	570	Shared Neighborhood Hits	19
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

MINT_MOUSE
θ value	0.813845 (rank : 141)	NC score	0.062188 (rank : 138)
Query Neighborhood Hits	293	Target Neighborhood Hits	1514	Shared Neighborhood Hits	112
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RGS3_HUMAN
θ value	0.813845 (rank : 142)	NC score	0.036042 (rank : 221)
Query Neighborhood Hits	293	Target Neighborhood Hits	1375	Shared Neighborhood Hits	75
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ULK1_MOUSE
θ value	0.813845 (rank : 143)	NC score	0.002230 (rank : 357)
Query Neighborhood Hits	293	Target Neighborhood Hits	1214	Shared Neighborhood Hits	43
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

BARH1_MOUSE
θ value	1.06291 (rank : 144)	NC score	0.007202 (rank : 335)
Query Neighborhood Hits	293	Target Neighborhood Hits	350	Shared Neighborhood Hits	8
SwissProt Accessions	P63157, Q9JK26	Gene names	Barhl1, Bhx1, Mbh2
Domain Architecture	No domain graphic available
Description	BarH-like 1 homeobox protein (Bar-class homeodomain protein MBH2) (BarH-related homeobox protein 1).

BAT2_MOUSE
θ value	1.06291 (rank : 145)	NC score	0.062559 (rank : 137)
Query Neighborhood Hits	293	Target Neighborhood Hits	947	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FILA_HUMAN
θ value	1.06291 (rank : 146)	NC score	0.048472 (rank : 200)
Query Neighborhood Hits	293	Target Neighborhood Hits	685	Shared Neighborhood Hits	62
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

JHD2B_MOUSE
θ value	1.06291 (rank : 147)	NC score	0.022763 (rank : 263)
Query Neighborhood Hits	293	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

NSD1_HUMAN
θ value	1.06291 (rank : 148)	NC score	0.030793 (rank : 243)
Query Neighborhood Hits	293	Target Neighborhood Hits	427	Shared Neighborhood Hits	47
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NU153_HUMAN
θ value	1.06291 (rank : 149)	NC score	0.033767 (rank : 231)
Query Neighborhood Hits	293	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

ZN516_MOUSE
θ value	1.06291 (rank : 150)	NC score	0.001535 (rank : 360)
Query Neighborhood Hits	293	Target Neighborhood Hits	1197	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN687_HUMAN
θ value	1.06291 (rank : 151)	NC score	0.007927 (rank : 330)
Query Neighborhood Hits	293	Target Neighborhood Hits	1244	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

AFF4_MOUSE
θ value	1.38821 (rank : 152)	NC score	0.070270 (rank : 117)
Query Neighborhood Hits	293	Target Neighborhood Hits	581	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

BEGIN_HUMAN
θ value	1.38821 (rank : 153)	NC score	0.019195 (rank : 280)
Query Neighborhood Hits	293	Target Neighborhood Hits	454	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CO4A_HUMAN
θ value	1.38821 (rank : 154)	NC score	0.015804 (rank : 296)
Query Neighborhood Hits	293	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

CO4B_HUMAN
θ value	1.38821 (rank : 155)	NC score	0.015796 (rank : 298)
Query Neighborhood Hits	293	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

DNMT1_HUMAN
θ value	1.38821 (rank : 156)	NC score	0.051472 (rank : 187)
Query Neighborhood Hits	293	Target Neighborhood Hits	401	Shared Neighborhood Hits	51
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

FZD6_MOUSE
θ value	1.38821 (rank : 157)	NC score	0.007094 (rank : 337)
Query Neighborhood Hits	293	Target Neighborhood Hits	135	Shared Neighborhood Hits	12
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

K1210_HUMAN
θ value	1.38821 (rank : 158)	NC score	0.056483 (rank : 160)
Query Neighborhood Hits	293	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

K1802_MOUSE
θ value	1.38821 (rank : 159)	NC score	0.034239 (rank : 229)
Query Neighborhood Hits	293	Target Neighborhood Hits	1596	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LUZP1_MOUSE
θ value	1.38821 (rank : 160)	NC score	0.015804 (rank : 297)
Query Neighborhood Hits	293	Target Neighborhood Hits	940	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MLH3_HUMAN
θ value	1.38821 (rank : 161)	NC score	0.023635 (rank : 261)
Query Neighborhood Hits	293	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

MUCDL_HUMAN
θ value	1.38821 (rank : 162)	NC score	0.037535 (rank : 217)
Query Neighborhood Hits	293	Target Neighborhood Hits	777	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

OXR1_MOUSE
θ value	1.38821 (rank : 163)	NC score	0.028270 (rank : 248)
Query Neighborhood Hits	293	Target Neighborhood Hits	516	Shared Neighborhood Hits	35
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PRG4_MOUSE
θ value	1.38821 (rank : 164)	NC score	0.091147 (rank : 93)
Query Neighborhood Hits	293	Target Neighborhood Hits	624	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TP53B_MOUSE
θ value	1.38821 (rank : 165)	NC score	0.053457 (rank : 177)
Query Neighborhood Hits	293	Target Neighborhood Hits	644	Shared Neighborhood Hits	71
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

UBP29_MOUSE
θ value	1.38821 (rank : 166)	NC score	0.457054 (rank : 68)
Query Neighborhood Hits	293	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

WNK2_HUMAN
θ value	1.38821 (rank : 167)	NC score	0.013904 (rank : 305)
Query Neighborhood Hits	293	Target Neighborhood Hits	1407	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

YTDC1_HUMAN
θ value	1.38821 (rank : 168)	NC score	0.047958 (rank : 201)
Query Neighborhood Hits	293	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

CAMKV_HUMAN
θ value	1.81305 (rank : 169)	NC score	0.005334 (rank : 351)
Query Neighborhood Hits	293	Target Neighborhood Hits	1084	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

FA48A_HUMAN
θ value	1.81305 (rank : 170)	NC score	0.020186 (rank : 275)
Query Neighborhood Hits	293	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

GAB2_HUMAN
θ value	1.81305 (rank : 171)	NC score	0.020399 (rank : 272)
Query Neighborhood Hits	293	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GON4L_HUMAN
θ value	1.81305 (rank : 172)	NC score	0.037475 (rank : 218)
Query Neighborhood Hits	293	Target Neighborhood Hits	555	Shared Neighborhood Hits	55
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MAGE1_HUMAN
θ value	1.81305 (rank : 173)	NC score	0.034451 (rank : 227)
Query Neighborhood Hits	293	Target Neighborhood Hits	1389	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP9_MOUSE
θ value	1.81305 (rank : 174)	NC score	0.024294 (rank : 257)
Query Neighborhood Hits	293	Target Neighborhood Hits	529	Shared Neighborhood Hits	30
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MAST4_HUMAN
θ value	1.81305 (rank : 175)	NC score	0.015005 (rank : 302)
Query Neighborhood Hits	293	Target Neighborhood Hits	1804	Shared Neighborhood Hits	113
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MISS_MOUSE
θ value	1.81305 (rank : 176)	NC score	0.027233 (rank : 250)
Query Neighborhood Hits	293	Target Neighborhood Hits	444	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PCLO_MOUSE
θ value	1.81305 (rank : 177)	NC score	0.067863 (rank : 123)
Query Neighborhood Hits	293	Target Neighborhood Hits	2275	Shared Neighborhood Hits	137
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PO121_MOUSE
θ value	1.81305 (rank : 178)	NC score	0.061810 (rank : 141)
Query Neighborhood Hits	293	Target Neighborhood Hits	345	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PTN22_HUMAN
θ value	1.81305 (rank : 179)	NC score	0.005130 (rank : 352)
Query Neighborhood Hits	293	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

SVIL_MOUSE
θ value	1.81305 (rank : 180)	NC score	0.027774 (rank : 249)
Query Neighborhood Hits	293	Target Neighborhood Hits	439	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TBCD4_MOUSE
θ value	1.81305 (rank : 181)	NC score	0.021904 (rank : 267)
Query Neighborhood Hits	293	Target Neighborhood Hits	276	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

BPTF_HUMAN
θ value	2.36792 (rank : 182)	NC score	0.039813 (rank : 214)
Query Neighborhood Hits	293	Target Neighborhood Hits	786	Shared Neighborhood Hits	80
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CDC7_MOUSE
θ value	2.36792 (rank : 183)	NC score	0.006525 (rank : 342)
Query Neighborhood Hits	293	Target Neighborhood Hits	641	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0H0, Q9Z2Y7	Gene names	Cdc7, Cdc7l1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (muCdc7).

CKAP2_HUMAN
θ value	2.36792 (rank : 184)	NC score	0.024006 (rank : 258)
Query Neighborhood Hits	293	Target Neighborhood Hits	116	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

CQ028_HUMAN
θ value	2.36792 (rank : 185)	NC score	0.018253 (rank : 287)
Query Neighborhood Hits	293	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

LRP1_HUMAN
θ value	2.36792 (rank : 186)	NC score	0.000192 (rank : 364)
Query Neighborhood Hits	293	Target Neighborhood Hits	617	Shared Neighborhood Hits	9
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MARK2_HUMAN
θ value	2.36792 (rank : 187)	NC score	0.004667 (rank : 354)
Query Neighborhood Hits	293	Target Neighborhood Hits	1056	Shared Neighborhood Hits	45
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MAST1_HUMAN
θ value	2.36792 (rank : 188)	NC score	0.006120 (rank : 346)
Query Neighborhood Hits	293	Target Neighborhood Hits	1146	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MLL3_HUMAN
θ value	2.36792 (rank : 189)	NC score	0.028811 (rank : 246)
Query Neighborhood Hits	293	Target Neighborhood Hits	1644	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYLK_HUMAN
θ value	2.36792 (rank : 190)	NC score	-0.000015 (rank : 366)
Query Neighborhood Hits	293	Target Neighborhood Hits	1328	Shared Neighborhood Hits	35
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NDC1_HUMAN
θ value	2.36792 (rank : 191)	NC score	0.016610 (rank : 293)
Query Neighborhood Hits	293	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BTX1, Q8NB76, Q9H9T6, Q9NSG3, Q9NSG4, Q9NVZ7	Gene names	TMEM48, NDC1
Domain Architecture	No domain graphic available
Description	Nucleoporin NDC1 (hNDC1) (Transmembrane protein 48).

NFIP2_HUMAN
θ value	2.36792 (rank : 192)	NC score	0.020260 (rank : 273)
Query Neighborhood Hits	293	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

SRRM2_MOUSE
θ value	2.36792 (rank : 193)	NC score	0.112209 (rank : 79)
Query Neighborhood Hits	293	Target Neighborhood Hits	1470	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRTD2_HUMAN
θ value	2.36792 (rank : 194)	NC score	0.020606 (rank : 271)
Query Neighborhood Hits	293	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

AKAP1_MOUSE
θ value	3.0926 (rank : 195)	NC score	0.018983 (rank : 281)
Query Neighborhood Hits	293	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

ATS7_HUMAN
θ value	3.0926 (rank : 196)	NC score	0.001369 (rank : 361)
Query Neighborhood Hits	293	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

GP112_HUMAN
θ value	3.0926 (rank : 197)	NC score	0.020218 (rank : 274)
Query Neighborhood Hits	293	Target Neighborhood Hits	441	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

JARD2_HUMAN
θ value	3.0926 (rank : 198)	NC score	0.031616 (rank : 241)
Query Neighborhood Hits	293	Target Neighborhood Hits	119	Shared Neighborhood Hits	20
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

PHF22_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.020832 (rank : 270)
Query Neighborhood Hits	293	Target Neighborhood Hits	121	Shared Neighborhood Hits	14
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PK1L1_HUMAN
θ value	3.0926 (rank : 200)	NC score	0.018336 (rank : 286)
Query Neighborhood Hits	293	Target Neighborhood Hits	140	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PMS2_HUMAN
θ value	3.0926 (rank : 201)	NC score	0.024435 (rank : 255)
Query Neighborhood Hits	293	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PRGC1_HUMAN
θ value	3.0926 (rank : 202)	NC score	0.031654 (rank : 240)
Query Neighborhood Hits	293	Target Neighborhood Hits	157	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

REPS1_MOUSE
θ value	3.0926 (rank : 203)	NC score	0.016513 (rank : 294)
Query Neighborhood Hits	293	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

REXO1_MOUSE
θ value	3.0926 (rank : 204)	NC score	0.030447 (rank : 244)
Query Neighborhood Hits	293	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

RFC1_HUMAN
θ value	3.0926 (rank : 205)	NC score	0.034926 (rank : 223)
Query Neighborhood Hits	293	Target Neighborhood Hits	352	Shared Neighborhood Hits	33
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RHG25_MOUSE
θ value	3.0926 (rank : 206)	NC score	0.009872 (rank : 321)
Query Neighborhood Hits	293	Target Neighborhood Hits	492	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SFR16_HUMAN
θ value	3.0926 (rank : 207)	NC score	0.046724 (rank : 202)
Query Neighborhood Hits	293	Target Neighborhood Hits	178	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N2M8, O96026, Q6UW71, Q96DX2	Gene names	SFRS16, SWAP2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2).

SPG11_HUMAN
θ value	3.0926 (rank : 208)	NC score	0.030963 (rank : 242)
Query Neighborhood Hits	293	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q08648, Q9H4P8, Q9H4Q0, Q9H4Q1, Q9H4Q2, Q9NRT3, Q9NRV4, Q9NRV5, Q9NRV6, Q9NRV7, Q9NRV8	Gene names	SPAG11, EP2, HE2
Domain Architecture
Description	Sperm-associated antigen 11 precursor (EP2 protein) (Sperm antigen HE2).

TCF20_MOUSE
θ value	3.0926 (rank : 209)	NC score	0.040395 (rank : 211)
Query Neighborhood Hits	293	Target Neighborhood Hits	396	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TERF2_HUMAN
θ value	3.0926 (rank : 210)	NC score	0.022144 (rank : 266)
Query Neighborhood Hits	293	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TNR21_MOUSE
θ value	3.0926 (rank : 211)	NC score	0.010160 (rank : 319)
Query Neighborhood Hits	293	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

ZIMP7_MOUSE
θ value	3.0926 (rank : 212)	NC score	0.017882 (rank : 288)
Query Neighborhood Hits	293	Target Neighborhood Hits	566	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

AATK_HUMAN
θ value	4.03905 (rank : 213)	NC score	0.001882 (rank : 359)
Query Neighborhood Hits	293	Target Neighborhood Hits	1243	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

DLGP1_HUMAN
θ value	4.03905 (rank : 214)	NC score	0.012541 (rank : 310)
Query Neighborhood Hits	293	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	O14490, O14489, P78335	Gene names	DLGAP1, DAP1, GKAP
Domain Architecture
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD- 95/SAP90-binding protein 1).

DLGP1_MOUSE
θ value	4.03905 (rank : 215)	NC score	0.012389 (rank : 312)
Query Neighborhood Hits	293	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D415, Q52KF6, Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0	Gene names	Dlgap1, Kiaa4162
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD-95/SAP90- binding protein 1).

ELOA1_HUMAN
θ value	4.03905 (rank : 216)	NC score	0.028487 (rank : 247)
Query Neighborhood Hits	293	Target Neighborhood Hits	388	Shared Neighborhood Hits	40
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

IER5_MOUSE
θ value	4.03905 (rank : 217)	NC score	0.023944 (rank : 259)
Query Neighborhood Hits	293	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

NEB1_HUMAN
θ value	4.03905 (rank : 218)	NC score	0.017257 (rank : 291)
Query Neighborhood Hits	293	Target Neighborhood Hits	829	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NHS_HUMAN
θ value	4.03905 (rank : 219)	NC score	0.036311 (rank : 220)
Query Neighborhood Hits	293	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

PHLB2_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.006220 (rank : 344)
Query Neighborhood Hits	293	Target Neighborhood Hits	964	Shared Neighborhood Hits	29
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SELPL_MOUSE
θ value	4.03905 (rank : 221)	NC score	0.050673 (rank : 195)
Query Neighborhood Hits	293	Target Neighborhood Hits	588	Shared Neighborhood Hits	60
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SEM6D_HUMAN
θ value	4.03905 (rank : 222)	NC score	0.007181 (rank : 336)
Query Neighborhood Hits	293	Target Neighborhood Hits	169	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6D_MOUSE
θ value	4.03905 (rank : 223)	NC score	0.006635 (rank : 341)
Query Neighborhood Hits	293	Target Neighborhood Hits	161	Shared Neighborhood Hits	14
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SRRM2_HUMAN
θ value	4.03905 (rank : 224)	NC score	0.112937 (rank : 78)
Query Neighborhood Hits	293	Target Neighborhood Hits	1296	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ADDB_MOUSE
θ value	5.27518 (rank : 225)	NC score	0.036516 (rank : 219)
Query Neighborhood Hits	293	Target Neighborhood Hits	574	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AKAP4_HUMAN
θ value	5.27518 (rank : 226)	NC score	0.009665 (rank : 323)
Query Neighborhood Hits	293	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

AKAP6_HUMAN
θ value	5.27518 (rank : 227)	NC score	0.013303 (rank : 307)
Query Neighborhood Hits	293	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

APC_HUMAN
θ value	5.27518 (rank : 228)	NC score	0.042094 (rank : 208)
Query Neighborhood Hits	293	Target Neighborhood Hits	603	Shared Neighborhood Hits	67
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APXL_HUMAN
θ value	5.27518 (rank : 229)	NC score	0.031772 (rank : 238)
Query Neighborhood Hits	293	Target Neighborhood Hits	553	Shared Neighborhood Hits	51
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BRCA1_MOUSE
θ value	5.27518 (rank : 230)	NC score	0.015667 (rank : 299)
Query Neighborhood Hits	293	Target Neighborhood Hits	436	Shared Neighborhood Hits	30
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

CK024_HUMAN
θ value	5.27518 (rank : 231)	NC score	0.058816 (rank : 148)
Query Neighborhood Hits	293	Target Neighborhood Hits	408	Shared Neighborhood Hits	53
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

DUT_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.019913 (rank : 277)
Query Neighborhood Hits	293	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

ESCO1_HUMAN
θ value	5.27518 (rank : 233)	NC score	0.032644 (rank : 235)
Query Neighborhood Hits	293	Target Neighborhood Hits	361	Shared Neighborhood Hits	40
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

ETV4_HUMAN
θ value	5.27518 (rank : 234)	NC score	0.003826 (rank : 355)
Query Neighborhood Hits	293	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

JADE1_MOUSE
θ value	5.27518 (rank : 235)	NC score	0.005047 (rank : 353)
Query Neighborhood Hits	293	Target Neighborhood Hits	160	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

K0240_HUMAN
θ value	5.27518 (rank : 236)	NC score	0.011131 (rank : 318)
Query Neighborhood Hits	293	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

LPP_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.013296 (rank : 308)
Query Neighborhood Hits	293	Target Neighborhood Hits	775	Shared Neighborhood Hits	50
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAP1B_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.055345 (rank : 166)
Query Neighborhood Hits	293	Target Neighborhood Hits	903	Shared Neighborhood Hits	87
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYCD_HUMAN
θ value	5.27518 (rank : 239)	NC score	0.012449 (rank : 311)
Query Neighborhood Hits	293	Target Neighborhood Hits	167	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

NFM_HUMAN
θ value	5.27518 (rank : 240)	NC score	0.023748 (rank : 260)
Query Neighborhood Hits	293	Target Neighborhood Hits	1328	Shared Neighborhood Hits	72
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

OGFR_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.043908 (rank : 207)
Query Neighborhood Hits	293	Target Neighborhood Hits	1582	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SHAN2_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.021583 (rank : 268)
Query Neighborhood Hits	293	Target Neighborhood Hits	346	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SKI_MOUSE
θ value	5.27518 (rank : 243)	NC score	0.006291 (rank : 343)
Query Neighborhood Hits	293	Target Neighborhood Hits	423	Shared Neighborhood Hits	14
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

TCGAP_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.019519 (rank : 279)
Query Neighborhood Hits	293	Target Neighborhood Hits	872	Shared Neighborhood Hits	51
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

UBP26_MOUSE
θ value	5.27518 (rank : 245)	NC score	0.375077 (rank : 69)
Query Neighborhood Hits	293	Target Neighborhood Hits	107	Shared Neighborhood Hits	72
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

ZN638_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.018494 (rank : 284)
Query Neighborhood Hits	293	Target Neighborhood Hits	318	Shared Neighborhood Hits	24
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

AFF3_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.033639 (rank : 233)
Query Neighborhood Hits	293	Target Neighborhood Hits	190	Shared Neighborhood Hits	37
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

ANC2_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.007958 (rank : 329)
Query Neighborhood Hits	293	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

CNGB3_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.008579 (rank : 326)
Query Neighborhood Hits	293	Target Neighborhood Hits	206	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CTND2_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.012741 (rank : 309)
Query Neighborhood Hits	293	Target Neighborhood Hits	333	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

GP179_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.026313 (rank : 253)
Query Neighborhood Hits	293	Target Neighborhood Hits	372	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

K0020_MOUSE
θ value	6.88961 (rank : 252)	NC score	0.011231 (rank : 316)
Query Neighborhood Hits	293	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BKS9, Q6A0E6, Q8BU15	Gene names	Kiaa0020
Domain Architecture	No domain graphic available
Description	Protein KIAA0020.

KCNK4_MOUSE
θ value	6.88961 (rank : 253)	NC score	0.006057 (rank : 347)
Query Neighborhood Hits	293	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

LNX2_MOUSE
θ value	6.88961 (rank : 254)	NC score	0.008464 (rank : 327)
Query Neighborhood Hits	293	Target Neighborhood Hits	407	Shared Neighborhood Hits	15
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

M3K3_HUMAN
θ value	6.88961 (rank : 255)	NC score	0.000288 (rank : 363)
Query Neighborhood Hits	293	Target Neighborhood Hits	885	Shared Neighborhood Hits	23
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

NMDE1_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.003452 (rank : 356)
Query Neighborhood Hits	293	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NOTC3_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.000178 (rank : 365)
Query Neighborhood Hits	293	Target Neighborhood Hits	975	Shared Neighborhood Hits	24
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PCGF4_MOUSE
θ value	6.88961 (rank : 258)	NC score	0.006049 (rank : 348)
Query Neighborhood Hits	293	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PLK3_MOUSE
θ value	6.88961 (rank : 259)	NC score	-0.001572 (rank : 367)
Query Neighborhood Hits	293	Target Neighborhood Hits	863	Shared Neighborhood Hits	15
SwissProt Accessions	Q60806, Q60822, Q9R009	Gene names	Plk3, Cnk, Fnk
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase).

PODO_MOUSE
θ value	6.88961 (rank : 260)	NC score	0.007352 (rank : 333)
Query Neighborhood Hits	293	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q91X05, Q8BWE6, Q91Z95	Gene names	Nphs2
Domain Architecture
Description	Podocin.

RHG12_HUMAN
θ value	6.88961 (rank : 261)	NC score	0.006163 (rank : 345)
Query Neighborhood Hits	293	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RIMS1_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.031751 (rank : 239)
Query Neighborhood Hits	293	Target Neighborhood Hits	437	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RL1D1_HUMAN
θ value	6.88961 (rank : 263)	NC score	0.060657 (rank : 142)
Query Neighborhood Hits	293	Target Neighborhood Hits	180	Shared Neighborhood Hits	46
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

TBX2_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.011205 (rank : 317)
Query Neighborhood Hits	293	Target Neighborhood Hits	195	Shared Neighborhood Hits	22
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TRPM3_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.006670 (rank : 340)
Query Neighborhood Hits	293	Target Neighborhood Hits	121	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TULP2_HUMAN
θ value	6.88961 (rank : 266)	NC score	0.006741 (rank : 339)
Query Neighborhood Hits	293	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	O00295	Gene names	TULP2
Domain Architecture
Description	Tubby-related protein 2 (Tubby-like protein 2).

VPS72_MOUSE
θ value	6.88961 (rank : 267)	NC score	0.015531 (rank : 300)
Query Neighborhood Hits	293	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ZCH11_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.014997 (rank : 303)
Query Neighborhood Hits	293	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

ZCPW1_MOUSE
θ value	6.88961 (rank : 269)	NC score	0.033298 (rank : 234)
Query Neighborhood Hits	293	Target Neighborhood Hits	307	Shared Neighborhood Hits	34
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

CAC1G_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.011611 (rank : 315)
Query Neighborhood Hits	293	Target Neighborhood Hits	587	Shared Neighborhood Hits	47
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CR025_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.012129 (rank : 314)
Query Neighborhood Hits	293	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q96B23, Q5XG78, Q6N058, Q86TB5, Q8TCQ5	Gene names	C18orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25.

DCX_MOUSE
θ value	8.99809 (rank : 272)	NC score	0.006883 (rank : 338)
Query Neighborhood Hits	293	Target Neighborhood Hits	124	Shared Neighborhood Hits	17
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

DIDO1_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.034201 (rank : 230)
Query Neighborhood Hits	293	Target Neighborhood Hits	960	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DOT1L_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.032128 (rank : 237)
Query Neighborhood Hits	293	Target Neighborhood Hits	660	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DPOLL_MOUSE
θ value	8.99809 (rank : 275)	NC score	0.007763 (rank : 332)
Query Neighborhood Hits	293	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

EVL_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.019977 (rank : 276)
Query Neighborhood Hits	293	Target Neighborhood Hits	203	Shared Neighborhood Hits	35
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FANCJ_MOUSE
θ value	8.99809 (rank : 277)	NC score	0.008108 (rank : 328)
Query Neighborhood Hits	293	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

GA2L2_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.022592 (rank : 264)
Query Neighborhood Hits	293	Target Neighborhood Hits	175	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

GAB2_MOUSE
θ value	8.99809 (rank : 279)	NC score	0.016491 (rank : 295)
Query Neighborhood Hits	293	Target Neighborhood Hits	220	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

HNF1A_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.012265 (rank : 313)
Query Neighborhood Hits	293	Target Neighborhood Hits	193	Shared Neighborhood Hits	22
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

K0423_MOUSE
θ value	8.99809 (rank : 281)	NC score	0.022578 (rank : 265)
Query Neighborhood Hits	293	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

KCD18_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.009711 (rank : 322)
Query Neighborhood Hits	293	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

MACF1_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.000731 (rank : 362)
Query Neighborhood Hits	293	Target Neighborhood Hits	1313	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MCPH1_MOUSE
θ value	8.99809 (rank : 284)	NC score	0.018782 (rank : 283)
Query Neighborhood Hits	293	Target Neighborhood Hits	116	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

PARM1_MOUSE
θ value	8.99809 (rank : 285)	NC score	0.041330 (rank : 209)
Query Neighborhood Hits	293	Target Neighborhood Hits	140	Shared Neighborhood Hits	34
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PRGC2_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.018798 (rank : 282)
Query Neighborhood Hits	293	Target Neighborhood Hits	272	Shared Neighborhood Hits	30
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

SEPT9_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.013495 (rank : 306)
Query Neighborhood Hits	293	Target Neighborhood Hits	706	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SFRIP_HUMAN
θ value	8.99809 (rank : 288)	NC score	0.060384 (rank : 143)
Query Neighborhood Hits	293	Target Neighborhood Hits	530	Shared Neighborhood Hits	67
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SMBP2_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.007881 (rank : 331)
Query Neighborhood Hits	293	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

TARSH_HUMAN
θ value	8.99809 (rank : 290)	NC score	0.052595 (rank : 181)
Query Neighborhood Hits	293	Target Neighborhood Hits	768	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TTF1_MOUSE
θ value	8.99809 (rank : 291)	NC score	0.034802 (rank : 225)
Query Neighborhood Hits	293	Target Neighborhood Hits	277	Shared Neighborhood Hits	31
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

UBQL2_MOUSE
θ value	8.99809 (rank : 292)	NC score	0.005527 (rank : 350)
Query Neighborhood Hits	293	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

ZN750_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.018414 (rank : 285)
Query Neighborhood Hits	293	Target Neighborhood Hits	183	Shared Neighborhood Hits	26
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ACINU_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.054773 (rank : 170)
Query Neighborhood Hits	293	Target Neighborhood Hits	828	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.051312 (rank : 190)
Query Neighborhood Hits	293	Target Neighborhood Hits	712	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AF9_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.050555 (rank : 196)
Query Neighborhood Hits	293	Target Neighborhood Hits	202	Shared Neighborhood Hits	39
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

AFF1_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.065219 (rank : 128)
Query Neighborhood Hits	293	Target Neighborhood Hits	506	Shared Neighborhood Hits	80
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF1_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.057001 (rank : 158)
Query Neighborhood Hits	293	Target Neighborhood Hits	351	Shared Neighborhood Hits	73
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AFF4_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.063595 (rank : 133)
Query Neighborhood Hits	293	Target Neighborhood Hits	611	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

BASP_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.101098 (rank : 86)
Query Neighborhood Hits	293	Target Neighborhood Hits	321	Shared Neighborhood Hits	66
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.096740 (rank : 90)
Query Neighborhood Hits	293	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BRAP_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.091498 (rank : 92)
Query Neighborhood Hits	293	Target Neighborhood Hits	560	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.105025 (rank : 83)
Query Neighborhood Hits	293	Target Neighborhood Hits	409	Shared Neighborhood Hits	22
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CJ078_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.054948 (rank : 169)
Query Neighborhood Hits	293	Target Neighborhood Hits	559	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.073809 (rank : 108)
Query Neighborhood Hits	293	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CYLC1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.051931 (rank : 186)
Query Neighborhood Hits	293	Target Neighborhood Hits	408	Shared Neighborhood Hits	48
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CYLC2_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.061946 (rank : 140)
Query Neighborhood Hits	293	Target Neighborhood Hits	223	Shared Neighborhood Hits	33
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DMP1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.055610 (rank : 164)
Query Neighborhood Hits	293	Target Neighborhood Hits	491	Shared Neighborhood Hits	52
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DMP1_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.064202 (rank : 131)
Query Neighborhood Hits	293	Target Neighborhood Hits	498	Shared Neighborhood Hits	57
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.074369 (rank : 107)
Query Neighborhood Hits	293	Target Neighborhood Hits	645	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.069848 (rank : 119)
Query Neighborhood Hits	293	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ENL_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.104696 (rank : 84)
Query Neighborhood Hits	293	Target Neighborhood Hits	305	Shared Neighborhood Hits	70
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

GGNB1_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.096234 (rank : 91)
Query Neighborhood Hits	293	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GGNB1_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.129425 (rank : 74)
Query Neighborhood Hits	293	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GNAS3_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.062150 (rank : 139)
Query Neighborhood Hits	293	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

GPTC8_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.067125 (rank : 124)
Query Neighborhood Hits	293	Target Neighborhood Hits	366	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

GRIN1_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.064662 (rank : 130)
Query Neighborhood Hits	293	Target Neighborhood Hits	337	Shared Neighborhood Hits	61
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.053702 (rank : 175)
Query Neighborhood Hits	293	Target Neighborhood Hits	674	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HDAC6_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.072349 (rank : 112)
Query Neighborhood Hits	293	Target Neighborhood Hits	145	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HDAC6_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.073453 (rank : 109)
Query Neighborhood Hits	293	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

HIRP3_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.054428 (rank : 172)
Query Neighborhood Hits	293	Target Neighborhood Hits	323	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

IWS1_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.055905 (rank : 163)
Query Neighborhood Hits	293	Target Neighborhood Hits	1258	Shared Neighborhood Hits	90
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KI67_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.050002 (rank : 198)
Query Neighborhood Hits	293	Target Neighborhood Hits	581	Shared Neighborhood Hits	61
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MAP4_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.066069 (rank : 126)
Query Neighborhood Hits	293	Target Neighborhood Hits	428	Shared Neighborhood Hits	69
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.073221 (rank : 110)
Query Neighborhood Hits	293	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MARCS_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.069244 (rank : 121)
Query Neighborhood Hits	293	Target Neighborhood Hits	227	Shared Neighborhood Hits	49
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MINT_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.055091 (rank : 168)
Query Neighborhood Hits	293	Target Neighborhood Hits	1291	Shared Neighborhood Hits	114
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUC2_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.053621 (rank : 176)
Query Neighborhood Hits	293	Target Neighborhood Hits	906	Shared Neighborhood Hits	85
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.077725 (rank : 104)
Query Neighborhood Hits	293	Target Neighborhood Hits	538	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NEUM_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.054642 (rank : 171)
Query Neighborhood Hits	293	Target Neighborhood Hits	132	Shared Neighborhood Hits	33
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.059975 (rank : 146)
Query Neighborhood Hits	293	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NFH_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.053247 (rank : 178)
Query Neighborhood Hits	293	Target Neighborhood Hits	1242	Shared Neighborhood Hits	107
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOLC1_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.118158 (rank : 75)
Query Neighborhood Hits	293	Target Neighborhood Hits	452	Shared Neighborhood Hits	103
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NSBP1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.057779 (rank : 154)
Query Neighborhood Hits	293	Target Neighborhood Hits	251	Shared Neighborhood Hits	26
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NUCKS_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.059252 (rank : 147)
Query Neighborhood Hits	293	Target Neighborhood Hits	143	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PO121_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.052531 (rank : 182)
Query Neighborhood Hits	293	Target Neighborhood Hits	344	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PPRB_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.050884 (rank : 192)
Query Neighborhood Hits	293	Target Neighborhood Hits	311	Shared Neighborhood Hits	59
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PPRB_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.057909 (rank : 153)
Query Neighborhood Hits	293	Target Neighborhood Hits	354	Shared Neighborhood Hits	71
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRB3_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.063112 (rank : 135)
Query Neighborhood Hits	293	Target Neighborhood Hits	318	Shared Neighborhood Hits	50
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.065576 (rank : 127)
Query Neighborhood Hits	293	Target Neighborhood Hits	330	Shared Neighborhood Hits	51
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.090768 (rank : 94)
Query Neighborhood Hits	293	Target Neighborhood Hits	764	Shared Neighborhood Hits	103
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.084988 (rank : 97)
Query Neighborhood Hits	293	Target Neighborhood Hits	385	Shared Neighborhood Hits	58
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.058251 (rank : 150)
Query Neighborhood Hits	293	Target Neighborhood Hits	347	Shared Neighborhood Hits	47
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.058554 (rank : 149)
Query Neighborhood Hits	293	Target Neighborhood Hits	460	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RBBP6_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.057980 (rank : 152)
Query Neighborhood Hits	293	Target Neighborhood Hits	1014	Shared Neighborhood Hits	84
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RERE_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.051357 (rank : 188)
Query Neighborhood Hits	293	Target Neighborhood Hits	779	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.052470 (rank : 183)
Query Neighborhood Hits	293	Target Neighborhood Hits	785	Shared Neighborhood Hits	85
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RP1L1_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.060276 (rank : 144)
Query Neighborhood Hits	293	Target Neighborhood Hits	1072	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SET1A_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.057005 (rank : 157)
Query Neighborhood Hits	293	Target Neighborhood Hits	690	Shared Neighborhood Hits	87
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SFR11_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.055234 (rank : 167)
Query Neighborhood Hits	293	Target Neighborhood Hits	246	Shared Neighborhood Hits	37
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFR12_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.050367 (rank : 197)
Query Neighborhood Hits	293	Target Neighborhood Hits	486	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SFR17_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.057315 (rank : 155)
Query Neighborhood Hits	293	Target Neighborhood Hits	325	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SFRS4_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.052714 (rank : 180)
Query Neighborhood Hits	293	Target Neighborhood Hits	406	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SON_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.051317 (rank : 189)
Query Neighborhood Hits	293	Target Neighborhood Hits	957	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRRM1_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.108504 (rank : 80)
Query Neighborhood Hits	293	Target Neighborhood Hits	690	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

T2FA_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.070324 (rank : 116)
Query Neighborhood Hits	293	Target Neighborhood Hits	228	Shared Neighborhood Hits	52
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TAF4_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.052722 (rank : 179)
Query Neighborhood Hits	293	Target Neighborhood Hits	687	Shared Neighborhood Hits	59
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TBCD3_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.060169 (rank : 145)
Query Neighborhood Hits	293	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

TCOF_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.084361 (rank : 98)
Query Neighborhood Hits	293	Target Neighborhood Hits	543	Shared Neighborhood Hits	94
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.097063 (rank : 89)
Query Neighborhood Hits	293	Target Neighborhood Hits	471	Shared Neighborhood Hits	92
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TGON1_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.056380 (rank : 162)
Query Neighborhood Hits	293	Target Neighborhood Hits	243	Shared Neighborhood Hits	41
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TGON2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.052429 (rank : 184)
Query Neighborhood Hits	293	Target Neighborhood Hits	277	Shared Neighborhood Hits	39
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

THOC2_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.052195 (rank : 185)
Query Neighborhood Hits	293	Target Neighborhood Hits	337	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TRDN_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.058143 (rank : 151)
Query Neighborhood Hits	293	Target Neighborhood Hits	542	Shared Neighborhood Hits	54
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

VCX1_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.056404 (rank : 161)
Query Neighborhood Hits	293	Target Neighborhood Hits	129	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.057061 (rank : 156)
Query Neighborhood Hits	293	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.056775 (rank : 159)
Query Neighborhood Hits	293	Target Neighborhood Hits	139	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

WASIP_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.055491 (rank : 165)
Query Neighborhood Hits	293	Target Neighborhood Hits	458	Shared Neighborhood Hits	62
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

Hits sorted by NC score

UBP31_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	293	Target Neighborhood Hits	293	Shared Neighborhood Hits	293
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP43_MOUSE
NC score	0.944435 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	293	Target Neighborhood Hits	130	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_HUMAN
NC score	0.942843 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	293	Target Neighborhood Hits	144	Shared Neighborhood Hits	84
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP4_HUMAN
NC score	0.841695 (rank : 4)	θ value	3.37985e-39 (rank : 6)
Query Neighborhood Hits	293	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
NC score	0.840470 (rank : 5)	θ value	7.52953e-39 (rank : 7)
Query Neighborhood Hits	293	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP15_MOUSE
NC score	0.839926 (rank : 6)	θ value	2.58786e-39 (rank : 5)
Query Neighborhood Hits	293	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP15_HUMAN
NC score	0.839711 (rank : 7)	θ value	1.51715e-39 (rank : 4)
Query Neighborhood Hits	293	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP11_HUMAN
NC score	0.838468 (rank : 8)	θ value	8.91499e-32 (rank : 8)
Query Neighborhood Hits	293	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP2_MOUSE
NC score	0.833747 (rank : 9)	θ value	6.18819e-25 (rank : 14)
Query Neighborhood Hits	293	Target Neighborhood Hits	86	Shared Neighborhood Hits	75
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_HUMAN
NC score	0.831888 (rank : 10)	θ value	4.01107e-24 (rank : 15)
Query Neighborhood Hits	293	Target Neighborhood Hits	84	Shared Neighborhood Hits	75
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP50_MOUSE
NC score	0.828605 (rank : 11)	θ value	1.62847e-25 (rank : 13)
Query Neighborhood Hits	293	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP8_MOUSE
NC score	0.824387 (rank : 12)	θ value	3.74554e-30 (rank : 10)
Query Neighborhood Hits	293	Target Neighborhood Hits	362	Shared Neighborhood Hits	91
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP20_HUMAN
NC score	0.819789 (rank : 13)	θ value	7.30988e-26 (rank : 12)
Query Neighborhood Hits	293	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP33_HUMAN
NC score	0.816883 (rank : 14)	θ value	1.92365e-26 (rank : 11)
Query Neighborhood Hits	293	Target Neighborhood Hits	157	Shared Neighborhood Hits	76
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP21_MOUSE
NC score	0.815158 (rank : 15)	θ value	1.74391e-19 (rank : 24)
Query Neighborhood Hits	293	Target Neighborhood Hits	101	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP3_HUMAN
NC score	0.814461 (rank : 16)	θ value	4.15078e-21 (rank : 19)
Query Neighborhood Hits	293	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP50_HUMAN
NC score	0.814456 (rank : 17)	θ value	2.7842e-17 (rank : 25)
Query Neighborhood Hits	293	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP21_HUMAN
NC score	0.813773 (rank : 18)	θ value	1.74391e-19 (rank : 23)
Query Neighborhood Hits	293	Target Neighborhood Hits	95	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP3_MOUSE
NC score	0.813103 (rank : 19)	θ value	1.2077e-20 (rank : 20)
Query Neighborhood Hits	293	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP51_HUMAN
NC score	0.801915 (rank : 20)	θ value	3.75424e-22 (rank : 16)
Query Neighborhood Hits	293	Target Neighborhood Hits	162	Shared Neighborhood Hits	87
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP22_MOUSE
NC score	0.794902 (rank : 21)	θ value	2.06002e-20 (rank : 21)
Query Neighborhood Hits	293	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
NC score	0.793804 (rank : 22)	θ value	3.51386e-20 (rank : 22)
Query Neighborhood Hits	293	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP8_HUMAN
NC score	0.791829 (rank : 23)	θ value	3.74554e-30 (rank : 9)
Query Neighborhood Hits	293	Target Neighborhood Hits	751	Shared Neighborhood Hits	107
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP16_HUMAN
NC score	0.769781 (rank : 24)	θ value	5.43371e-13 (rank : 31)
Query Neighborhood Hits	293	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP44_HUMAN
NC score	0.762764 (rank : 25)	θ value	1.38178e-16 (rank : 27)
Query Neighborhood Hits	293	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_MOUSE
NC score	0.751879 (rank : 26)	θ value	6.20254e-17 (rank : 26)
Query Neighborhood Hits	293	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_HUMAN
NC score	0.750405 (rank : 27)	θ value	1.38178e-16 (rank : 28)
Query Neighborhood Hits	293	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBPW_MOUSE
NC score	0.744523 (rank : 28)	θ value	7.84624e-12 (rank : 32)
Query Neighborhood Hits	293	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP18_HUMAN
NC score	0.744073 (rank : 29)	θ value	3.76295e-14 (rank : 30)
Query Neighborhood Hits	293	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP18_MOUSE
NC score	0.732143 (rank : 30)	θ value	2.88119e-14 (rank : 29)
Query Neighborhood Hits	293	Target Neighborhood Hits	77	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UB17L_HUMAN
NC score	0.727963 (rank : 31)	θ value	8.67504e-11 (rank : 35)
Query Neighborhood Hits	293	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP36_HUMAN
NC score	0.727578 (rank : 32)	θ value	2.52405e-10 (rank : 37)
Query Neighborhood Hits	293	Target Neighborhood Hits	232	Shared Neighborhood Hits	103
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP32_HUMAN
NC score	0.727519 (rank : 33)	θ value	1.86321e-21 (rank : 17)
Query Neighborhood Hits	293	Target Neighborhood Hits	170	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP12_HUMAN
NC score	0.721825 (rank : 34)	θ value	5.26297e-08 (rank : 42)
Query Neighborhood Hits	293	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP46_HUMAN
NC score	0.718197 (rank : 35)	θ value	3.08544e-08 (rank : 40)
Query Neighborhood Hits	293	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.718197 (rank : 36)	θ value	3.08544e-08 (rank : 41)
Query Neighborhood Hits	293	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP42_HUMAN
NC score	0.714190 (rank : 37)	θ value	1.47974e-10 (rank : 36)
Query Neighborhood Hits	293	Target Neighborhood Hits	445	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP48_HUMAN
NC score	0.689285 (rank : 38)	θ value	1.33837e-11 (rank : 33)
Query Neighborhood Hits	293	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.688163 (rank : 39)	θ value	1.33837e-11 (rank : 34)
Query Neighborhood Hits	293	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP6_HUMAN
NC score	0.686880 (rank : 40)	θ value	3.17815e-21 (rank : 18)
Query Neighborhood Hits	293	Target Neighborhood Hits	188	Shared Neighborhood Hits	81
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP30_HUMAN
NC score	0.669187 (rank : 41)	θ value	7.59969e-07 (rank : 47)
Query Neighborhood Hits	293	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP1_HUMAN
NC score	0.627059 (rank : 42)	θ value	0.000121331 (rank : 65)
Query Neighborhood Hits	293	Target Neighborhood Hits	259	Shared Neighborhood Hits	88
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP24_HUMAN
NC score	0.619293 (rank : 43)	θ value	8.97725e-08 (rank : 44)
Query Neighborhood Hits	293	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP35_HUMAN
NC score	0.613046 (rank : 44)	θ value	3.77169e-06 (rank : 49)
Query Neighborhood Hits	293	Target Neighborhood Hits	223	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP40_HUMAN
NC score	0.608074 (rank : 45)	θ value	9.29e-05 (rank : 63)
Query Neighborhood Hits	293	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP10_MOUSE
NC score	0.607191 (rank : 46)	θ value	0.00020696 (rank : 67)
Query Neighborhood Hits	293	Target Neighborhood Hits	150	Shared Neighborhood Hits	82
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP7_HUMAN
NC score	0.604922 (rank : 47)	θ value	4.92598e-06 (rank : 51)
Query Neighborhood Hits	293	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP10_HUMAN
NC score	0.603688 (rank : 48)	θ value	1.43324e-05 (rank : 57)
Query Neighborhood Hits	293	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP47_MOUSE
NC score	0.592553 (rank : 49)	θ value	2.44474e-05 (rank : 60)
Query Neighborhood Hits	293	Target Neighborhood Hits	135	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

SNUT2_MOUSE
NC score	0.590308 (rank : 50)	θ value	0.000786445 (rank : 71)
Query Neighborhood Hits	293	Target Neighborhood Hits	80	Shared Neighborhood Hits	62
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP47_HUMAN
NC score	0.589904 (rank : 51)	θ value	3.77169e-06 (rank : 50)
Query Neighborhood Hits	293	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP38_HUMAN
NC score	0.586727 (rank : 52)	θ value	6.43352e-06 (rank : 53)
Query Neighborhood Hits	293	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
NC score	0.584236 (rank : 53)	θ value	1.09739e-05 (rank : 56)
Query Neighborhood Hits	293	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

SNUT2_HUMAN
NC score	0.583890 (rank : 54)	θ value	0.000786445 (rank : 70)
Query Neighborhood Hits	293	Target Neighborhood Hits	79	Shared Neighborhood Hits	62
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP37_HUMAN
NC score	0.566451 (rank : 55)	θ value	3.19293e-05 (rank : 61)
Query Neighborhood Hits	293	Target Neighborhood Hits	208	Shared Neighborhood Hits	77
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP34_HUMAN
NC score	0.560063 (rank : 56)	θ value	5.26297e-08 (rank : 43)
Query Neighborhood Hits	293	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
NC score	0.559127 (rank : 57)	θ value	1.53129e-07 (rank : 45)
Query Neighborhood Hits	293	Target Neighborhood Hits	189	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

USP9X_HUMAN
NC score	0.550858 (rank : 58)	θ value	1.80886e-08 (rank : 38)
Query Neighborhood Hits	293	Target Neighborhood Hits	161	Shared Neighborhood Hits	76
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.549709 (rank : 59)	θ value	1.80886e-08 (rank : 39)
Query Neighborhood Hits	293	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9Y_HUMAN
NC score	0.546470 (rank : 60)	θ value	2.61198e-07 (rank : 46)
Query Neighborhood Hits	293	Target Neighborhood Hits	109	Shared Neighborhood Hits	75
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP14_HUMAN
NC score	0.532590 (rank : 61)	θ value	0.279714 (rank : 118)
Query Neighborhood Hits	293	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
NC score	0.519667 (rank : 62)	θ value	0.279714 (rank : 119)
Query Neighborhood Hits	293	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP29_HUMAN
NC score	0.495323 (rank : 63)	θ value	0.00228821 (rank : 75)
Query Neighborhood Hits	293	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP13_HUMAN
NC score	0.489518 (rank : 64)	θ value	8.40245e-06 (rank : 54)
Query Neighborhood Hits	293	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP26_HUMAN
NC score	0.488371 (rank : 65)	θ value	1.87187e-05 (rank : 58)
Query Neighborhood Hits	293	Target Neighborhood Hits	108	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP5_HUMAN
NC score	0.479613 (rank : 66)	θ value	7.1131e-05 (rank : 62)
Query Neighborhood Hits	293	Target Neighborhood Hits	109	Shared Neighborhood Hits	74
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
NC score	0.474870 (rank : 67)	θ value	0.00020696 (rank : 68)
Query Neighborhood Hits	293	Target Neighborhood Hits	106	Shared Neighborhood Hits	74
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP29_MOUSE
NC score	0.457054 (rank : 68)	θ value	1.38821 (rank : 166)
Query Neighborhood Hits	293	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_MOUSE
NC score	0.375077 (rank : 69)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	293	Target Neighborhood Hits	107	Shared Neighborhood Hits	72
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP28_MOUSE
NC score	0.339327 (rank : 70)	θ value	0.0736092 (rank : 93)
Query Neighborhood Hits	293	Target Neighborhood Hits	178	Shared Neighborhood Hits	78
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
NC score	0.338152 (rank : 71)	θ value	0.0961366 (rank : 97)
Query Neighborhood Hits	293	Target Neighborhood Hits	117	Shared Neighborhood Hits	77
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP25_MOUSE
NC score	0.312618 (rank : 72)	θ value	0.62314 (rank : 136)
Query Neighborhood Hits	293	Target Neighborhood Hits	116	Shared Neighborhood Hits	73
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.310829 (rank : 73)	θ value	0.62314 (rank : 135)
Query Neighborhood Hits	293	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

GGNB1_MOUSE
NC score	0.129425 (rank : 74)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	293	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

NOLC1_HUMAN
NC score	0.118158 (rank : 75)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	293	Target Neighborhood Hits	452	Shared Neighborhood Hits	103
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

LAD1_HUMAN
NC score	0.117469 (rank : 76)	θ value	0.000158464 (rank : 66)
Query Neighborhood Hits	293	Target Neighborhood Hits	441	Shared Neighborhood Hits	54
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SRRM1_MOUSE
NC score	0.114531 (rank : 77)	θ value	0.279714 (rank : 116)
Query Neighborhood Hits	293	Target Neighborhood Hits	966	Shared Neighborhood Hits	123
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
NC score	0.112937 (rank : 78)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	293	Target Neighborhood Hits	1296	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.112209 (rank : 79)	θ value	2.36792 (rank : 193)
Query Neighborhood Hits	293	Target Neighborhood Hits	1470	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM1_HUMAN
NC score	0.108504 (rank : 80)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	293	Target Neighborhood Hits	690	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

NPBL_MOUSE
NC score	0.106707 (rank : 81)	θ value	2.44474e-05 (rank : 59)
Query Neighborhood Hits	293	Target Neighborhood Hits	1041	Shared Neighborhood Hits	92
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

LAD1_MOUSE
NC score	0.105243 (rank : 82)	θ value	0.00102713 (rank : 72)
Query Neighborhood Hits	293	Target Neighborhood Hits	391	Shared Neighborhood Hits	52
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

BRAP_MOUSE
NC score	0.105025 (rank : 83)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	293	Target Neighborhood Hits	409	Shared Neighborhood Hits	22
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

ENL_HUMAN
NC score	0.104696 (rank : 84)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	293	Target Neighborhood Hits	305	Shared Neighborhood Hits	70
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

TGON2_HUMAN
NC score	0.102184 (rank : 85)	θ value	1.09739e-05 (rank : 55)
Query Neighborhood Hits	293	Target Neighborhood Hits	1037	Shared Neighborhood Hits	96
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

BASP_HUMAN
NC score	0.101098 (rank : 86)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	293	Target Neighborhood Hits	321	Shared Neighborhood Hits	66
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

NIPBL_HUMAN
NC score	0.098977 (rank : 87)	θ value	0.000121331 (rank : 64)
Query Neighborhood Hits	293	Target Neighborhood Hits	1311	Shared Neighborhood Hits	103
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MDC1_HUMAN
NC score	0.098015 (rank : 88)	θ value	0.00298849 (rank : 76)
Query Neighborhood Hits	293	Target Neighborhood Hits	1446	Shared Neighborhood Hits	113
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TCOF_MOUSE
NC score	0.097063 (rank : 89)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	293	Target Neighborhood Hits	471	Shared Neighborhood Hits	92
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

BASP_MOUSE
NC score	0.096740 (rank : 90)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	293	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

GGNB1_HUMAN
NC score	0.096234 (rank : 91)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	293	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

BRAP_HUMAN
NC score	0.091498 (rank : 92)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	293	Target Neighborhood Hits	560	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

PRG4_MOUSE
NC score	0.091147 (rank : 93)	θ value	1.38821 (rank : 164)
Query Neighborhood Hits	293	Target Neighborhood Hits	624	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_HUMAN
NC score	0.090768 (rank : 94)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	293	Target Neighborhood Hits	764	Shared Neighborhood Hits	103
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MAP4_MOUSE
NC score	0.087680 (rank : 95)	θ value	0.00869519 (rank : 82)
Query Neighborhood Hits	293	Target Neighborhood Hits	409	Shared Neighborhood Hits	72
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NACAM_MOUSE
NC score	0.087566 (rank : 96)	θ value	0.00228821 (rank : 73)
Query Neighborhood Hits	293	Target Neighborhood Hits	1866	Shared Neighborhood Hits	136
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRP1_HUMAN
NC score	0.084988 (rank : 97)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	293	Target Neighborhood Hits	385	Shared Neighborhood Hits	58
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

TCOF_HUMAN
NC score	0.084361 (rank : 98)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	293	Target Neighborhood Hits	543	Shared Neighborhood Hits	94
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MDC1_MOUSE
NC score	0.081729 (rank : 99)	θ value	0.0431538 (rank : 90)
Query Neighborhood Hits	293	Target Neighborhood Hits	998	Shared Neighborhood Hits	88
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PCLO_HUMAN
NC score	0.079114 (rank : 100)	θ value	0.125558 (rank : 102)
Query Neighborhood Hits	293	Target Neighborhood Hits	2046	Shared Neighborhood Hits	135
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MUC1_MOUSE
NC score	0.078740 (rank : 101)	θ value	0.365318 (rank : 124)
Query Neighborhood Hits	293	Target Neighborhood Hits	388	Shared Neighborhood Hits	57
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

TXND2_MOUSE
NC score	0.078733 (rank : 102)	θ value	0.000461057 (rank : 69)
Query Neighborhood Hits	293	Target Neighborhood Hits	828	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CJ012_HUMAN
NC score	0.078709 (rank : 103)	θ value	0.365318 (rank : 121)
Query Neighborhood Hits	293	Target Neighborhood Hits	467	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

MUC7_HUMAN
NC score	0.077725 (rank : 104)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	293	Target Neighborhood Hits	538	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

BSN_HUMAN
NC score	0.076986 (rank : 105)	θ value	0.125558 (rank : 98)
Query Neighborhood Hits	293	Target Neighborhood Hits	1537	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DACT1_HUMAN
NC score	0.074970 (rank : 106)	θ value	0.0736092 (rank : 91)
Query Neighborhood Hits	293	Target Neighborhood Hits	228	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

DSPP_HUMAN
NC score	0.074369 (rank : 107)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	293	Target Neighborhood Hits	645	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CN155_HUMAN
NC score	0.073809 (rank : 108)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	293	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

HDAC6_MOUSE
NC score	0.073453 (rank : 109)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	293	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

MARCS_HUMAN
NC score	0.073221 (rank : 110)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	293	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

BAT2_HUMAN
NC score	0.072526 (rank : 111)	θ value	0.813845 (rank : 137)
Query Neighborhood Hits	293	Target Neighborhood Hits	931	Shared Neighborhood Hits	90
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

HDAC6_HUMAN
NC score	0.072349 (rank : 112)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	293	Target Neighborhood Hits	145	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

TARA_HUMAN
NC score	0.071443 (rank : 113)	θ value	0.00390308 (rank : 77)
Query Neighborhood Hits	293	Target Neighborhood Hits	1626	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DACT1_MOUSE
NC score	0.071377 (rank : 114)	θ value	0.0113563 (rank : 83)
Query Neighborhood Hits	293	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

RBBP6_HUMAN
NC score	0.071087 (rank : 115)	θ value	0.00509761 (rank : 78)
Query Neighborhood Hits	293	Target Neighborhood Hits	1135	Shared Neighborhood Hits	84
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

T2FA_HUMAN
NC score	0.070324 (rank : 116)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	293	Target Neighborhood Hits	228	Shared Neighborhood Hits	52
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

AFF4_MOUSE
NC score	0.070270 (rank : 117)	θ value	1.38821 (rank : 152)
Query Neighborhood Hits	293	Target Neighborhood Hits	581	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

BSN_MOUSE
NC score	0.069900 (rank : 118)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	293	Target Neighborhood Hits	2057	Shared Neighborhood Hits	134
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DSPP_MOUSE
NC score	0.069848 (rank : 119)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	293	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TXND2_HUMAN
NC score	0.069764 (rank : 120)	θ value	0.47712 (rank : 128)
Query Neighborhood Hits	293	Target Neighborhood Hits	793	Shared Neighborhood Hits	77
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MARCS_MOUSE
NC score	0.069244 (rank : 121)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	293	Target Neighborhood Hits	227	Shared Neighborhood Hits	49
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

GRIN1_HUMAN
NC score	0.067867 (rank : 122)	θ value	0.0736092 (rank : 92)
Query Neighborhood Hits	293	Target Neighborhood Hits	681	Shared Neighborhood Hits	72
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PCLO_MOUSE
NC score	0.067863 (rank : 123)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	293	Target Neighborhood Hits	2275	Shared Neighborhood Hits	137
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GPTC8_HUMAN
NC score	0.067125 (rank : 124)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	293	Target Neighborhood Hits	366	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

CARD6_HUMAN
NC score	0.066707 (rank : 125)	θ value	0.0330416 (rank : 87)
Query Neighborhood Hits	293	Target Neighborhood Hits	145	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BX69	Gene names	CARD6
Domain Architecture
Description	Caspase recruitment domain-containing protein 6.

MAP4_HUMAN
NC score	0.066069 (rank : 126)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	293	Target Neighborhood Hits	428	Shared Neighborhood Hits	69
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PRB4S_HUMAN
NC score	0.065576 (rank : 127)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	293	Target Neighborhood Hits	330	Shared Neighborhood Hits	51
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

AFF1_HUMAN
NC score	0.065219 (rank : 128)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	293	Target Neighborhood Hits	506	Shared Neighborhood Hits	80
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

PDZD2_HUMAN
NC score	0.064716 (rank : 129)	θ value	0.00228821 (rank : 74)
Query Neighborhood Hits	293	Target Neighborhood Hits	772	Shared Neighborhood Hits	81
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

GRIN1_MOUSE
NC score	0.064662 (rank : 130)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	293	Target Neighborhood Hits	337	Shared Neighborhood Hits	61
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DMP1_MOUSE
NC score	0.064202 (rank : 131)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	293	Target Neighborhood Hits	498	Shared Neighborhood Hits	57
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

IWS1_HUMAN
NC score	0.064168 (rank : 132)	θ value	0.21417 (rank : 107)
Query Neighborhood Hits	293	Target Neighborhood Hits	1241	Shared Neighborhood Hits	91
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AFF4_HUMAN
NC score	0.063595 (rank : 133)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	293	Target Neighborhood Hits	611	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

NFH_MOUSE
NC score	0.063459 (rank : 134)	θ value	1.69304e-06 (rank : 48)
Query Neighborhood Hits	293	Target Neighborhood Hits	2247	Shared Neighborhood Hits	139
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRB3_HUMAN
NC score	0.063112 (rank : 135)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	293	Target Neighborhood Hits	318	Shared Neighborhood Hits	50
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

MBB1A_HUMAN
NC score	0.062947 (rank : 136)	θ value	0.0330416 (rank : 89)
Query Neighborhood Hits	293	Target Neighborhood Hits	665	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

BAT2_MOUSE
NC score	0.062559 (rank : 137)	θ value	1.06291 (rank : 145)
Query Neighborhood Hits	293	Target Neighborhood Hits	947	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MINT_MOUSE
NC score	0.062188 (rank : 138)	θ value	0.813845 (rank : 141)
Query Neighborhood Hits	293	Target Neighborhood Hits	1514	Shared Neighborhood Hits	112
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GNAS3_HUMAN
NC score	0.062150 (rank : 139)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	293	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

CYLC2_HUMAN
NC score	0.061946 (rank : 140)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	293	Target Neighborhood Hits	223	Shared Neighborhood Hits	33
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

PO121_MOUSE
NC score	0.061810 (rank : 141)	θ value	1.81305 (rank : 178)
Query Neighborhood Hits	293	Target Neighborhood Hits	345	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RL1D1_HUMAN
NC score	0.060657 (rank : 142)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	293	Target Neighborhood Hits	180	Shared Neighborhood Hits	46
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SFRIP_HUMAN
NC score	0.060384 (rank : 143)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	293	Target Neighborhood Hits	530	Shared Neighborhood Hits	67
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

RP1L1_HUMAN
NC score	0.060276 (rank : 144)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	293	Target Neighborhood Hits	1072	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TBCD3_HUMAN
NC score	0.060169 (rank : 145)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	293	Target Neighborhood Hits	51	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

NEUM_MOUSE
NC score	0.059975 (rank : 146)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	293	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NUCKS_HUMAN
NC score	0.059252 (rank : 147)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	293	Target Neighborhood Hits	143	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

CK024_HUMAN
NC score	0.058816 (rank : 148)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	293	Target Neighborhood Hits	408	Shared Neighborhood Hits	53
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

PRR12_HUMAN
NC score	0.058554 (rank : 149)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	293	Target Neighborhood Hits	460	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRP2_MOUSE
NC score	0.058251 (rank : 150)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	293	Target Neighborhood Hits	347	Shared Neighborhood Hits	47
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

TRDN_HUMAN
NC score	0.058143 (rank : 151)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	293	Target Neighborhood Hits	542	Shared Neighborhood Hits	54
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

RBBP6_MOUSE
NC score	0.057980 (rank : 152)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	293	Target Neighborhood Hits	1014	Shared Neighborhood Hits	84
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

PPRB_MOUSE
NC score	0.057909 (rank : 153)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	293	Target Neighborhood Hits	354	Shared Neighborhood Hits	71
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

NSBP1_HUMAN
NC score	0.057779 (rank : 154)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	293	Target Neighborhood Hits	251	Shared Neighborhood Hits	26
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

SFR17_HUMAN
NC score	0.057315 (rank : 155)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	293	Target Neighborhood Hits	325	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

VCX3_HUMAN
NC score	0.057061 (rank : 156)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	293	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

SET1A_HUMAN
NC score	0.057005 (rank : 157)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	293	Target Neighborhood Hits	690	Shared Neighborhood Hits	87
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

AFF1_MOUSE
NC score	0.057001 (rank : 158)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	293	Target Neighborhood Hits	351	Shared Neighborhood Hits	73
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

VCXC_HUMAN
NC score	0.056775 (rank : 159)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	293	Target Neighborhood Hits	139	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

K1210_HUMAN
NC score	0.056483 (rank : 160)	θ value	1.38821 (rank : 158)
Query Neighborhood Hits	293	Target Neighborhood Hits	219	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

VCX1_HUMAN
NC score	0.056404 (rank : 161)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	293	Target Neighborhood Hits	129	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

TGON1_MOUSE
NC score	0.056380 (rank : 162)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	293	Target Neighborhood Hits	243	Shared Neighborhood Hits	41
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

IWS1_MOUSE
NC score	0.055905 (rank : 163)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	293	Target Neighborhood Hits	1258	Shared Neighborhood Hits	90
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DMP1_HUMAN
NC score	0.055610 (rank : 164)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	293	Target Neighborhood Hits	491	Shared Neighborhood Hits	52
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

WASIP_HUMAN
NC score	0.055491 (rank : 165)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	293	Target Neighborhood Hits	458	Shared Neighborhood Hits	62
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MAP1B_HUMAN
NC score	0.055345 (rank : 166)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	293	Target Neighborhood Hits	903	Shared Neighborhood Hits	87
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SFR11_HUMAN
NC score	0.055234 (rank : 167)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	293	Target Neighborhood Hits	246	Shared Neighborhood Hits	37
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

MINT_HUMAN
NC score	0.055091 (rank : 168)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	293	Target Neighborhood Hits	1291	Shared Neighborhood Hits	114
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CJ078_MOUSE
NC score	0.054948 (rank : 169)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	293	Target Neighborhood Hits	559	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ACINU_HUMAN
NC score	0.054773 (rank : 170)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	293	Target Neighborhood Hits	828	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NEUM_HUMAN
NC score	0.054642 (rank : 171)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	293	Target Neighborhood Hits	132	Shared Neighborhood Hits	33
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

HIRP3_HUMAN
NC score	0.054428 (rank : 172)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	293	Target Neighborhood Hits	323	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

RGS3_MOUSE
NC score	0.053829 (rank : 173)	θ value	0.00509761 (rank : 79)
Query Neighborhood Hits	293	Target Neighborhood Hits	1621	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NOL8_HUMAN
NC score	0.053815 (rank : 174)	θ value	0.0252991 (rank : 85)
Query Neighborhood Hits	293	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

GSCR1_HUMAN
NC score	0.053702 (rank : 175)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	293	Target Neighborhood Hits	674	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MUC2_HUMAN
NC score	0.053621 (rank : 176)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	293	Target Neighborhood Hits	906	Shared Neighborhood Hits	85
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TP53B_MOUSE
NC score	0.053457 (rank : 177)	θ value	1.38821 (rank : 165)
Query Neighborhood Hits	293	Target Neighborhood Hits	644	Shared Neighborhood Hits	71
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

NFH_HUMAN
NC score	0.053247 (rank : 178)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	293	Target Neighborhood Hits	1242	Shared Neighborhood Hits	107
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TAF4_HUMAN
NC score	0.052722 (rank : 179)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	293	Target Neighborhood Hits	687	Shared Neighborhood Hits	59
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SFRS4_MOUSE
NC score	0.052714 (rank : 180)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	293	Target Neighborhood Hits	406	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TARSH_HUMAN
NC score	0.052595 (rank : 181)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	293	Target Neighborhood Hits	768	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PO121_HUMAN
NC score	0.052531 (rank : 182)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	293	Target Neighborhood Hits	344	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RERE_MOUSE
NC score	0.052470 (rank : 183)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	293	Target Neighborhood Hits	785	Shared Neighborhood Hits	85
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TGON2_MOUSE
NC score	0.052429 (rank : 184)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	293	Target Neighborhood Hits	277	Shared Neighborhood Hits	39
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

THOC2_HUMAN
NC score	0.052195 (rank : 185)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	293	Target Neighborhood Hits	337	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

CYLC1_HUMAN
NC score	0.051931 (rank : 186)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	293	Target Neighborhood Hits	408	Shared Neighborhood Hits	48
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DNMT1_HUMAN
NC score	0.051472 (rank : 187)	θ value	1.38821 (rank : 156)
Query Neighborhood Hits	293	Target Neighborhood Hits	401	Shared Neighborhood Hits	51
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

RERE_HUMAN
NC score	0.051357 (rank : 188)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	293	Target Neighborhood Hits	779	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SON_MOUSE
NC score	0.051317 (rank : 189)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	293	Target Neighborhood Hits	957	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ACINU_MOUSE
NC score	0.051312 (rank : 190)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	293	Target Neighborhood Hits	712	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

LYRIC_MOUSE
NC score	0.051068 (rank : 191)	θ value	0.21417 (rank : 110)
Query Neighborhood Hits	293	Target Neighborhood Hits	126	Shared Neighborhood Hits	23
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

PPRB_HUMAN
NC score	0.050884 (rank : 192)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	293	Target Neighborhood Hits	311	Shared Neighborhood Hits	59
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

AHTF1_MOUSE
NC score	0.050840 (rank : 193)	θ value	0.0330416 (rank : 86)
Query Neighborhood Hits	293	Target Neighborhood Hits	176	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CJF7, Q8BVJ5, Q8VD55	Gene names	Ahctf1, Elys
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

SON_HUMAN
NC score	0.050740 (rank : 194)	θ value	0.62314 (rank : 133)
Query Neighborhood Hits	293	Target Neighborhood Hits	1568	Shared Neighborhood Hits	98
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SELPL_MOUSE
NC score	0.050673 (rank : 195)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	293	Target Neighborhood Hits	588	Shared Neighborhood Hits	60
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

AF9_HUMAN
NC score	0.050555 (rank : 196)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	293	Target Neighborhood Hits	202	Shared Neighborhood Hits	39
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

SFR12_MOUSE
NC score	0.050367 (rank : 197)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	293	Target Neighborhood Hits	486	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

KI67_HUMAN
NC score	0.050002 (rank : 198)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	293	Target Neighborhood Hits	581	Shared Neighborhood Hits	61
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MUC5B_HUMAN
NC score	0.049361 (rank : 199)	θ value	0.00665767 (rank : 80)
Query Neighborhood Hits	293	Target Neighborhood Hits	1020	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

FILA_HUMAN
NC score	0.048472 (rank : 200)	θ value	1.06291 (rank : 146)
Query Neighborhood Hits	293	Target Neighborhood Hits	685	Shared Neighborhood Hits	62
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

YTDC1_HUMAN
NC score	0.047958 (rank : 201)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	293	Target Neighborhood Hits	458	Shared Neighborhood Hits	49
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

SFR16_HUMAN
NC score	0.046724 (rank : 202)	θ value	3.0926 (rank : 207)
Query Neighborhood Hits	293	Target Neighborhood Hits	178	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N2M8, O96026, Q6UW71, Q96DX2	Gene names	SFRS16, SWAP2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2).

JARD2_MOUSE
NC score	0.045419 (rank : 203)	θ value	0.0252991 (rank : 84)
Query Neighborhood Hits	293	Target Neighborhood Hits	169	Shared Neighborhood Hits	24
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

MUC1_HUMAN
NC score	0.045309 (rank : 204)	θ value	0.365318 (rank : 123)
Query Neighborhood Hits	293	Target Neighborhood Hits	975	Shared Neighborhood Hits	65
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CENPT_MOUSE
NC score	0.045166 (rank : 205)	θ value	0.813845 (rank : 138)
Query Neighborhood Hits	293	Target Neighborhood Hits	115	Shared Neighborhood Hits	27
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

MYCB2_HUMAN
NC score	0.044645 (rank : 206)	θ value	0.125558 (rank : 101)
Query Neighborhood Hits	293	Target Neighborhood Hits	390	Shared Neighborhood Hits	44
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

OGFR_HUMAN
NC score	0.043908 (rank : 207)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	293	Target Neighborhood Hits	1582	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

APC_HUMAN
NC score	0.042094 (rank : 208)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	293	Target Neighborhood Hits	603	Shared Neighborhood Hits	67
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PARM1_MOUSE
NC score	0.041330 (rank : 209)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	293	Target Neighborhood Hits	140	Shared Neighborhood Hits	34
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

DAB2_HUMAN
NC score	0.041310 (rank : 210)	θ value	0.163984 (rank : 104)
Query Neighborhood Hits	293	Target Neighborhood Hits	197	Shared Neighborhood Hits	25
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

TCF20_MOUSE
NC score	0.040395 (rank : 211)	θ value	3.0926 (rank : 209)
Query Neighborhood Hits	293	Target Neighborhood Hits	396	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

RIF1_HUMAN
NC score	0.040367 (rank : 212)	θ value	0.0961366 (rank : 96)
Query Neighborhood Hits	293	Target Neighborhood Hits	320	Shared Neighborhood Hits	29
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

DAB2_MOUSE
NC score	0.040168 (rank : 213)	θ value	0.62314 (rank : 131)
Query Neighborhood Hits	293	Target Neighborhood Hits	163	Shared Neighborhood Hits	24
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

BPTF_HUMAN
NC score	0.039813 (rank : 214)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	293	Target Neighborhood Hits	786	Shared Neighborhood Hits	80
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

ESPL1_MOUSE
NC score	0.039537 (rank : 215)	θ value	0.0330416 (rank : 88)
Query Neighborhood Hits	293	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

GA2L2_MOUSE
NC score	0.039158 (rank : 216)	θ value	0.163984 (rank : 105)
Query Neighborhood Hits	293	Target Neighborhood Hits	395	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

MUCDL_HUMAN
NC score	0.037535 (rank : 217)	θ value	1.38821 (rank : 162)
Query Neighborhood Hits	293	Target Neighborhood Hits	777	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

GON4L_HUMAN
NC score	0.037475 (rank : 218)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	293	Target Neighborhood Hits	555	Shared Neighborhood Hits	55
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ADDB_MOUSE
NC score	0.036516 (rank : 219)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	293	Target Neighborhood Hits	574	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

NHS_HUMAN
NC score	0.036311 (rank : 220)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	293	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

RGS3_HUMAN
NC score	0.036042 (rank : 221)	θ value	0.813845 (rank : 142)
Query Neighborhood Hits	293	Target Neighborhood Hits	1375	Shared Neighborhood Hits	75
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ANK2_HUMAN
NC score	0.035507 (rank : 222)	θ value	0.0961366 (rank : 94)
Query Neighborhood Hits	293	Target Neighborhood Hits	1615	Shared Neighborhood Hits	106
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RFC1_HUMAN
NC score	0.034926 (rank : 223)	θ value	3.0926 (rank : 205)
Query Neighborhood Hits	293	Target Neighborhood Hits	352	Shared Neighborhood Hits	33
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

K0423_HUMAN
NC score	0.034901 (rank : 224)	θ value	0.21417 (rank : 109)
Query Neighborhood Hits	293	Target Neighborhood Hits	171	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

TTF1_MOUSE
NC score	0.034802 (rank : 225)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	293	Target Neighborhood Hits	277	Shared Neighborhood Hits	31
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

JHD2C_MOUSE
NC score	0.034526 (rank : 226)	θ value	0.163984 (rank : 106)
Query Neighborhood Hits	293	Target Neighborhood Hits	297	Shared Neighborhood Hits	37
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

MAGE1_HUMAN
NC score	0.034451 (rank : 227)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	293	Target Neighborhood Hits	1389	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

INVS_MOUSE
NC score	0.034252 (rank : 228)	θ value	6.43352e-06 (rank : 52)
Query Neighborhood Hits	293	Target Neighborhood Hits	609	Shared Neighborhood Hits	46
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

K1802_MOUSE
NC score	0.034239 (rank : 229)	θ value	1.38821 (rank : 159)
Query Neighborhood Hits	293	Target Neighborhood Hits	1596	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

DIDO1_HUMAN
NC score	0.034201 (rank : 230)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	293	Target Neighborhood Hits	960	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

NU153_HUMAN
NC score	0.033767 (rank : 231)	θ value	1.06291 (rank : 149)
Query Neighborhood Hits	293	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

K0323_HUMAN
NC score	0.033657 (rank : 232)	θ value	0.21417 (rank : 108)
Query Neighborhood Hits	293	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

AFF3_HUMAN
NC score	0.033639 (rank : 233)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	293	Target Neighborhood Hits	190	Shared Neighborhood Hits	37
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

ZCPW1_MOUSE
NC score	0.033298 (rank : 234)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	293	Target Neighborhood Hits	307	Shared Neighborhood Hits	34
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ESCO1_HUMAN
NC score	0.032644 (rank : 235)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	293	Target Neighborhood Hits	361	Shared Neighborhood Hits	40
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

COA2_HUMAN
NC score	0.032601 (rank : 236)	θ value	0.125558 (rank : 99)
Query Neighborhood Hits	293	Target Neighborhood Hits	184	Shared Neighborhood Hits	26
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

DOT1L_HUMAN
NC score	0.032128 (rank : 237)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	293	Target Neighborhood Hits	660	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

APXL_HUMAN
NC score	0.031772 (rank : 238)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	293	Target Neighborhood Hits	553	Shared Neighborhood Hits	51
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

RIMS1_HUMAN
NC score	0.031751 (rank : 239)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	293	Target Neighborhood Hits	437	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PRGC1_HUMAN
NC score	0.031654 (rank : 240)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	293	Target Neighborhood Hits	157	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

JARD2_HUMAN
NC score	0.031616 (rank : 241)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	293	Target Neighborhood Hits	119	Shared Neighborhood Hits	20
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

SPG11_HUMAN
NC score	0.030963 (rank : 242)	θ value	3.0926 (rank : 208)
Query Neighborhood Hits	293	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q08648, Q9H4P8, Q9H4Q0, Q9H4Q1, Q9H4Q2, Q9NRT3, Q9NRV4, Q9NRV5, Q9NRV6, Q9NRV7, Q9NRV8	Gene names	SPAG11, EP2, HE2
Domain Architecture
Description	Sperm-associated antigen 11 precursor (EP2 protein) (Sperm antigen HE2).

NSD1_HUMAN
NC score	0.030793 (rank : 243)	θ value	1.06291 (rank : 148)
Query Neighborhood Hits	293	Target Neighborhood Hits	427	Shared Neighborhood Hits	47
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

REXO1_MOUSE
NC score	0.030447 (rank : 244)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	293	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

TTC28_HUMAN
NC score	0.029173 (rank : 245)	θ value	0.365318 (rank : 126)
Query Neighborhood Hits	293	Target Neighborhood Hits	271	Shared Neighborhood Hits	31
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

MLL3_HUMAN
NC score	0.028811 (rank : 246)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	293	Target Neighborhood Hits	1644	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ELOA1_HUMAN
NC score	0.028487 (rank : 247)	θ value	4.03905 (rank : 216)
Query Neighborhood Hits	293	Target Neighborhood Hits	388	Shared Neighborhood Hits	40
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

OXR1_MOUSE
NC score	0.028270 (rank : 248)	θ value	1.38821 (rank : 163)
Query Neighborhood Hits	293	Target Neighborhood Hits	516	Shared Neighborhood Hits	35
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

SVIL_MOUSE
NC score	0.027774 (rank : 249)	θ value	1.81305 (rank : 180)
Query Neighborhood Hits	293	Target Neighborhood Hits	439	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

MISS_MOUSE
NC score	0.027233 (rank : 250)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	293	Target Neighborhood Hits	444	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

RRBP1_MOUSE
NC score	0.026673 (rank : 251)	θ value	0.21417 (rank : 111)
Query Neighborhood Hits	293	Target Neighborhood Hits	1650	Shared Neighborhood Hits	71
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TIP60_MOUSE
NC score	0.026649 (rank : 252)	θ value	0.47712 (rank : 127)
Query Neighborhood Hits	293	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

GP179_HUMAN
NC score	0.026313 (rank : 253)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	293	Target Neighborhood Hits	372	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

TIP60_HUMAN
NC score	0.025841 (rank : 254)	θ value	0.62314 (rank : 134)
Query Neighborhood Hits	293	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

PMS2_HUMAN
NC score	0.024435 (rank : 255)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	293	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

COHA1_MOUSE
NC score	0.024402 (rank : 256)	θ value	0.62314 (rank : 130)
Query Neighborhood Hits	293	Target Neighborhood Hits	414	Shared Neighborhood Hits	40
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MAP9_MOUSE
NC score	0.024294 (rank : 257)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	293	Target Neighborhood Hits	529	Shared Neighborhood Hits	30
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

CKAP2_HUMAN
NC score	0.024006 (rank : 258)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	293	Target Neighborhood Hits	116	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

IER5_MOUSE
NC score	0.023944 (rank : 259)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	293	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

NFM_HUMAN
NC score	0.023748 (rank : 260)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	293	Target Neighborhood Hits	1328	Shared Neighborhood Hits	72
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

MLH3_HUMAN
NC score	0.023635 (rank : 261)	θ value	1.38821 (rank : 161)
Query Neighborhood Hits	293	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

NALP5_MOUSE
NC score	0.023588 (rank : 262)	θ value	0.62314 (rank : 132)
Query Neighborhood Hits	293	Target Neighborhood Hits	560	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

JHD2B_MOUSE
NC score	0.022763 (rank : 263)	θ value	1.06291 (rank : 147)
Query Neighborhood Hits	293	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

GA2L2_HUMAN
NC score	0.022592 (rank : 264)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	293	Target Neighborhood Hits	175	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

K0423_MOUSE
NC score	0.022578 (rank : 265)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	293	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

TERF2_HUMAN
NC score	0.022144 (rank : 266)	θ value	3.0926 (rank : 210)
Query Neighborhood Hits	293	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TBCD4_MOUSE
NC score	0.021904 (rank : 267)	θ value	1.81305 (rank : 181)
Query Neighborhood Hits	293	Target Neighborhood Hits	276	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

SHAN2_HUMAN
NC score	0.021583 (rank : 268)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	293	Target Neighborhood Hits	346	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

CC14A_HUMAN
NC score	0.020848 (rank : 269)	θ value	0.365318 (rank : 120)
Query Neighborhood Hits	293	Target Neighborhood Hits	133	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

PHF22_HUMAN
NC score	0.020832 (rank : 270)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	293	Target Neighborhood Hits	121	Shared Neighborhood Hits	14
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

SRTD2_HUMAN
NC score	0.020606 (rank : 271)	θ value	2.36792 (rank : 194)
Query Neighborhood Hits	293	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

GAB2_HUMAN
NC score	0.020399 (rank : 272)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	293	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

NFIP2_HUMAN
NC score	0.020260 (rank : 273)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	293	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NV92, Q7Z2H3, Q7Z428, Q8TAR3, Q9ULQ5	Gene names	NDFIP2, KIAA1165, N4WBP5A
Domain Architecture	No domain graphic available
Description	NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Putative MAPK-activating protein PM04/PM05/PM06/PM07) (Putative NF-kappa-B-activating protein 413).

GP112_HUMAN
NC score	0.020218 (rank : 274)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	293	Target Neighborhood Hits	441	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

FA48A_HUMAN
NC score	0.020186 (rank : 275)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	293	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

EVL_MOUSE
NC score	0.019977 (rank : 276)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	293	Target Neighborhood Hits	203	Shared Neighborhood Hits	35
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

DUT_HUMAN
NC score	0.019913 (rank : 277)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	293	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

MYO9B_HUMAN
NC score	0.019894 (rank : 278)	θ value	0.365318 (rank : 125)
Query Neighborhood Hits	293	Target Neighborhood Hits	641	Shared Neighborhood Hits	60
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TCGAP_HUMAN
NC score	0.019519 (rank : 279)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	293	Target Neighborhood Hits	872	Shared Neighborhood Hits	51
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BEGIN_HUMAN
NC score	0.019195 (rank : 280)	θ value	1.38821 (rank : 153)
Query Neighborhood Hits	293	Target Neighborhood Hits	454	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

AKAP1_MOUSE
NC score	0.018983 (rank : 281)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	293	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

PRGC2_HUMAN
NC score	0.018798 (rank : 282)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	293	Target Neighborhood Hits	272	Shared Neighborhood Hits	30
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

MCPH1_MOUSE
NC score	0.018782 (rank : 283)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	293	Target Neighborhood Hits	116	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

ZN638_MOUSE
NC score	0.018494 (rank : 284)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	293	Target Neighborhood Hits	318	Shared Neighborhood Hits	24
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

ZN750_HUMAN
NC score	0.018414 (rank : 285)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	293	Target Neighborhood Hits	183	Shared Neighborhood Hits	26
SwissProt Accessions	Q32MQ0, Q9H899	Gene names	ZNF750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

PK1L1_HUMAN
NC score	0.018336 (rank : 286)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	293	Target Neighborhood Hits	140	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

CQ028_HUMAN
NC score	0.018253 (rank : 287)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	293	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IV36, Q8N5L6, Q8TE83, Q9NT34	Gene names	C17orf28, DMC1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 (Down-regulated in multiple cancers- 1).

ZIMP7_MOUSE
NC score	0.017882 (rank : 288)	θ value	3.0926 (rank : 212)
Query Neighborhood Hits	293	Target Neighborhood Hits	566	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

TBX3_HUMAN
NC score	0.017641 (rank : 289)	θ value	0.279714 (rank : 117)
Query Neighborhood Hits	293	Target Neighborhood Hits	121	Shared Neighborhood Hits	16
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

IRF7_HUMAN
NC score	0.017394 (rank : 290)	θ value	0.813845 (rank : 139)
Query Neighborhood Hits	293	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

NEB1_HUMAN
NC score	0.017257 (rank : 291)	θ value	4.03905 (rank : 218)
Query Neighborhood Hits	293	Target Neighborhood Hits	829	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

MPDZ_HUMAN
NC score	0.016926 (rank : 292)	θ value	0.279714 (rank : 115)
Query Neighborhood Hits	293	Target Neighborhood Hits	261	Shared Neighborhood Hits	16
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NDC1_HUMAN
NC score	0.016610 (rank : 293)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	293	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BTX1, Q8NB76, Q9H9T6, Q9NSG3, Q9NSG4, Q9NVZ7	Gene names	TMEM48, NDC1
Domain Architecture	No domain graphic available
Description	Nucleoporin NDC1 (hNDC1) (Transmembrane protein 48).

REPS1_MOUSE
NC score	0.016513 (rank : 294)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	293	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

GAB2_MOUSE
NC score	0.016491 (rank : 295)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	293	Target Neighborhood Hits	220	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

CO4A_HUMAN
NC score	0.015804 (rank : 296)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	293	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

LUZP1_MOUSE
NC score	0.015804 (rank : 297)	θ value	1.38821 (rank : 160)
Query Neighborhood Hits	293	Target Neighborhood Hits	940	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

CO4B_HUMAN
NC score	0.015796 (rank : 298)	θ value	1.38821 (rank : 155)
Query Neighborhood Hits	293	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

BRCA1_MOUSE
NC score	0.015667 (rank : 299)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	293	Target Neighborhood Hits	436	Shared Neighborhood Hits	30
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

VPS72_MOUSE
NC score	0.015531 (rank : 300)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	293	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

MCM4_HUMAN
NC score	0.015485 (rank : 301)	θ value	0.279714 (rank : 114)
Query Neighborhood Hits	293	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MAST4_HUMAN
NC score	0.015005 (rank : 302)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	293	Target Neighborhood Hits	1804	Shared Neighborhood Hits	113
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ZCH11_HUMAN
NC score	0.014997 (rank : 303)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	293	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

BRWD1_MOUSE
NC score	0.014938 (rank : 304)	θ value	0.0961366 (rank : 95)
Query Neighborhood Hits	293	Target Neighborhood Hits	478	Shared Neighborhood Hits	26
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

WNK2_HUMAN
NC score	0.013904 (rank : 305)	θ value	1.38821 (rank : 167)
Query Neighborhood Hits	293	Target Neighborhood Hits	1407	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SEPT9_HUMAN
NC score	0.013495 (rank : 306)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	293	Target Neighborhood Hits	706	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

AKAP6_HUMAN
NC score	0.013303 (rank : 307)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	293	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

LPP_HUMAN
NC score	0.013296 (rank : 308)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	293	Target Neighborhood Hits	775	Shared Neighborhood Hits	50
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CTND2_HUMAN
NC score	0.012741 (rank : 309)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	293	Target Neighborhood Hits	333	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DLGP1_HUMAN
NC score	0.012541 (rank : 310)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	293	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	O14490, O14489, P78335	Gene names	DLGAP1, DAP1, GKAP
Domain Architecture
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD- 95/SAP90-binding protein 1).

MYCD_HUMAN
NC score	0.012449 (rank : 311)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	293	Target Neighborhood Hits	167	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

DLGP1_MOUSE
NC score	0.012389 (rank : 312)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	293	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D415, Q52KF6, Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0	Gene names	Dlgap1, Kiaa4162
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD-95/SAP90- binding protein 1).

HNF1A_HUMAN
NC score	0.012265 (rank : 313)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	293	Target Neighborhood Hits	193	Shared Neighborhood Hits	22
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

CR025_HUMAN
NC score	0.012129 (rank : 314)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	293	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q96B23, Q5XG78, Q6N058, Q86TB5, Q8TCQ5	Gene names	C18orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf25.

CAC1G_HUMAN
NC score	0.011611 (rank : 315)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	293	Target Neighborhood Hits	587	Shared Neighborhood Hits	47
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

K0020_MOUSE
NC score	0.011231 (rank : 316)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	293	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BKS9, Q6A0E6, Q8BU15	Gene names	Kiaa0020
Domain Architecture	No domain graphic available
Description	Protein KIAA0020.

TBX2_HUMAN
NC score	0.011205 (rank : 317)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	293	Target Neighborhood Hits	195	Shared Neighborhood Hits	22
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

K0240_HUMAN
NC score	0.011131 (rank : 318)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	293	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

TNR21_MOUSE
NC score	0.010160 (rank : 319)	θ value	3.0926 (rank : 211)
Query Neighborhood Hits	293	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

GP124_MOUSE
NC score	0.010132 (rank : 320)	θ value	0.279714 (rank : 113)
Query Neighborhood Hits	293	Target Neighborhood Hits	423	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

RHG25_MOUSE
NC score	0.009872 (rank : 321)	θ value	3.0926 (rank : 206)
Query Neighborhood Hits	293	Target Neighborhood Hits	492	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

KCD18_HUMAN
NC score	0.009711 (rank : 322)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	293	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

AKAP4_HUMAN
NC score	0.009665 (rank : 323)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	293	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JQC9, O60904, O95246, Q5JQD1, Q5JQD2, Q5JQD3	Gene names	AKAP4, AKAP82
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI).

LIPB2_MOUSE
NC score	0.009645 (rank : 324)	θ value	0.813845 (rank : 140)
Query Neighborhood Hits	293	Target Neighborhood Hits	570	Shared Neighborhood Hits	19
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

BARH1_HUMAN
NC score	0.009306 (rank : 325)	θ value	0.163984 (rank : 103)
Query Neighborhood Hits	293	Target Neighborhood Hits	373	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BZE3, Q9NY88	Gene names	BARHL1
Domain Architecture
Description	BarH-like 1 homeobox protein.

CNGB3_HUMAN
NC score	0.008579 (rank : 326)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	293	Target Neighborhood Hits	206	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

LNX2_MOUSE
NC score	0.008464 (rank : 327)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	293	Target Neighborhood Hits	407	Shared Neighborhood Hits	15
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

FANCJ_MOUSE
NC score	0.008108 (rank : 328)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	293	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

ANC2_HUMAN
NC score	0.007958 (rank : 329)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	293	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJX6, Q5VSG1, Q96DG5, Q96GG4, Q9P2E1	Gene names	ANAPC2, APC2, KIAA1406
Domain Architecture
Description	Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2).

ZN687_HUMAN
NC score	0.007927 (rank : 330)	θ value	1.06291 (rank : 151)
Query Neighborhood Hits	293	Target Neighborhood Hits	1244	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

SMBP2_MOUSE
NC score	0.007881 (rank : 331)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	293	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

DPOLL_MOUSE
NC score	0.007763 (rank : 332)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	293	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

PODO_MOUSE
NC score	0.007352 (rank : 333)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	293	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q91X05, Q8BWE6, Q91Z95	Gene names	Nphs2
Domain Architecture
Description	Podocin.

CDKL5_HUMAN
NC score	0.007348 (rank : 334)	θ value	0.00869519 (rank : 81)
Query Neighborhood Hits	293	Target Neighborhood Hits	967	Shared Neighborhood Hits	38
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

BARH1_MOUSE
NC score	0.007202 (rank : 335)	θ value	1.06291 (rank : 144)
Query Neighborhood Hits	293	Target Neighborhood Hits	350	Shared Neighborhood Hits	8
SwissProt Accessions	P63157, Q9JK26	Gene names	Barhl1, Bhx1, Mbh2
Domain Architecture	No domain graphic available
Description	BarH-like 1 homeobox protein (Bar-class homeodomain protein MBH2) (BarH-related homeobox protein 1).

SEM6D_HUMAN
NC score	0.007181 (rank : 336)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	293	Target Neighborhood Hits	169	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

FZD6_MOUSE
NC score	0.007094 (rank : 337)	θ value	1.38821 (rank : 157)
Query Neighborhood Hits	293	Target Neighborhood Hits	135	Shared Neighborhood Hits	12
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

DCX_MOUSE
NC score	0.006883 (rank : 338)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	293	Target Neighborhood Hits	124	Shared Neighborhood Hits	17
SwissProt Accessions	O88809	Gene names	Dcx, Dcn
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

TULP2_HUMAN
NC score	0.006741 (rank : 339)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	293	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	O00295	Gene names	TULP2
Domain Architecture
Description	Tubby-related protein 2 (Tubby-like protein 2).

TRPM3_HUMAN
NC score	0.006670 (rank : 340)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	293	Target Neighborhood Hits	121	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

SEM6D_MOUSE
NC score	0.006635 (rank : 341)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	293	Target Neighborhood Hits	161	Shared Neighborhood Hits	14
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

CDC7_MOUSE
NC score	0.006525 (rank : 342)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	293	Target Neighborhood Hits	641	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0H0, Q9Z2Y7	Gene names	Cdc7, Cdc7l1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (muCdc7).

SKI_MOUSE
NC score	0.006291 (rank : 343)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	293	Target Neighborhood Hits	423	Shared Neighborhood Hits	14
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

PHLB2_HUMAN
NC score	0.006220 (rank : 344)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	293	Target Neighborhood Hits	964	Shared Neighborhood Hits	29
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RHG12_HUMAN
NC score	0.006163 (rank : 345)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	293	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

MAST1_HUMAN
NC score	0.006120 (rank : 346)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	293	Target Neighborhood Hits	1146	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

KCNK4_MOUSE
NC score	0.006057 (rank : 347)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	293	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

PCGF4_MOUSE
NC score	0.006049 (rank : 348)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	293	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

MARK2_MOUSE
NC score	0.005578 (rank : 349)	θ value	0.125558 (rank : 100)
Query Neighborhood Hits	293	Target Neighborhood Hits	1018	Shared Neighborhood Hits	48
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

UBQL2_MOUSE
NC score	0.005527 (rank : 350)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	293	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

CAMKV_HUMAN
NC score	0.005334 (rank : 351)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	293	Target Neighborhood Hits	1084	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

PTN22_HUMAN
NC score	0.005130 (rank : 352)	θ value	1.81305 (rank : 179)
Query Neighborhood Hits	293	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

JADE1_MOUSE
NC score	0.005047 (rank : 353)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	293	Target Neighborhood Hits	160	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

MARK2_HUMAN
NC score	0.004667 (rank : 354)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	293	Target Neighborhood Hits	1056	Shared Neighborhood Hits	45
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

ETV4_HUMAN
NC score	0.003826 (rank : 355)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	293	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

NMDE1_MOUSE
NC score	0.003452 (rank : 356)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	293	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

ULK1_MOUSE
NC score	0.002230 (rank : 357)	θ value	0.813845 (rank : 143)
Query Neighborhood Hits	293	Target Neighborhood Hits	1214	Shared Neighborhood Hits	43
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

M3K3_MOUSE
NC score	0.001958 (rank : 358)	θ value	0.365318 (rank : 122)
Query Neighborhood Hits	293	Target Neighborhood Hits	876	Shared Neighborhood Hits	26
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

AATK_HUMAN
NC score	0.001882 (rank : 359)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	293	Target Neighborhood Hits	1243	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ZN516_MOUSE
NC score	0.001535 (rank : 360)	θ value	1.06291 (rank : 150)
Query Neighborhood Hits	293	Target Neighborhood Hits	1197	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ATS7_HUMAN
NC score	0.001369 (rank : 361)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	293	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

MACF1_MOUSE
NC score	0.000731 (rank : 362)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	293	Target Neighborhood Hits	1313	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

M3K3_HUMAN
NC score	0.000288 (rank : 363)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	293	Target Neighborhood Hits	885	Shared Neighborhood Hits	23
SwissProt Accessions	Q99759	Gene names	MAP3K3, MAPKKK3, MEKK3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

LRP1_HUMAN
NC score	0.000192 (rank : 364)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	293	Target Neighborhood Hits	617	Shared Neighborhood Hits	9
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

NOTC3_MOUSE
NC score	0.000178 (rank : 365)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	293	Target Neighborhood Hits	975	Shared Neighborhood Hits	24
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

MYLK_HUMAN
NC score	-0.000015 (rank : 366)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	293	Target Neighborhood Hits	1328	Shared Neighborhood Hits	35
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PLK3_MOUSE
NC score	-0.001572 (rank : 367)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	293	Target Neighborhood Hits	863	Shared Neighborhood Hits	15
SwissProt Accessions	Q60806, Q60822, Q9R009	Gene names	Plk3, Cnk, Fnk
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase).

ZN473_MOUSE
NC score	-0.004942 (rank : 368)	θ value	0.21417 (rank : 112)
Query Neighborhood Hits	293	Target Neighborhood Hits	824	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BI67, Q8BI98, Q8BIB7	Gene names	Znf473, Zfp100, Zfp473
Domain Architecture	No domain graphic available
Description	Zinc finger protein 473 homolog (Zinc finger protein 100) (Zfp-100).