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Network neighborhood for query Sequence : UBP47_HUMAN

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UBP47_HUMAN
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP47_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	149
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_MOUSE
θ value	0 (rank : 2)	NC score	0.995727 (rank : 2)
Query Neighborhood Hits	149	Target Neighborhood Hits	135	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP7_HUMAN
θ value	1.41672e-45 (rank : 3)	NC score	0.876781 (rank : 3)
Query Neighborhood Hits	149	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP40_HUMAN
θ value	4.41421e-39 (rank : 4)	NC score	0.861892 (rank : 4)
Query Neighborhood Hits	149	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP48_HUMAN
θ value	5.96599e-36 (rank : 5)	NC score	0.839317 (rank : 6)
Query Neighborhood Hits	149	Target Neighborhood Hits	101	Shared Neighborhood Hits	72
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP18_HUMAN
θ value	2.50655e-34 (rank : 6)	NC score	0.856857 (rank : 5)
Query Neighborhood Hits	149	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP24_HUMAN
θ value	6.82597e-32 (rank : 7)	NC score	0.823503 (rank : 9)
Query Neighborhood Hits	149	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP48_MOUSE
θ value	1.52067e-31 (rank : 8)	NC score	0.832109 (rank : 7)
Query Neighborhood Hits	149	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

USP9Y_HUMAN
θ value	3.3877e-31 (rank : 9)	NC score	0.763105 (rank : 16)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

USP9X_MOUSE
θ value	4.89182e-30 (rank : 10)	NC score	0.753572 (rank : 19)
Query Neighborhood Hits	149	Target Neighborhood Hits	171	Shared Neighborhood Hits	72
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP34_HUMAN
θ value	8.3442e-30 (rank : 11)	NC score	0.771259 (rank : 13)
Query Neighborhood Hits	149	Target Neighborhood Hits	210	Shared Neighborhood Hits	77
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

USP9X_HUMAN
θ value	5.40856e-29 (rank : 12)	NC score	0.754386 (rank : 18)
Query Neighborhood Hits	149	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP34_MOUSE
θ value	1.2049e-28 (rank : 13)	NC score	0.771126 (rank : 14)
Query Neighborhood Hits	149	Target Neighborhood Hits	189	Shared Neighborhood Hits	76
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP18_MOUSE
θ value	3.50572e-28 (rank : 14)	NC score	0.828521 (rank : 8)
Query Neighborhood Hits	149	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP12_HUMAN
θ value	2.69047e-20 (rank : 15)	NC score	0.790106 (rank : 10)
Query Neighborhood Hits	149	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP36_HUMAN
θ value	1.02238e-19 (rank : 16)	NC score	0.758303 (rank : 17)
Query Neighborhood Hits	149	Target Neighborhood Hits	232	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP46_HUMAN
θ value	8.10077e-17 (rank : 17)	NC score	0.787479 (rank : 11)
Query Neighborhood Hits	149	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	8.10077e-17 (rank : 18)	NC score	0.787479 (rank : 12)
Query Neighborhood Hits	149	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP42_HUMAN
θ value	1.80466e-16 (rank : 19)	NC score	0.718962 (rank : 24)
Query Neighborhood Hits	149	Target Neighborhood Hits	445	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP22_HUMAN
θ value	2.60593e-15 (rank : 20)	NC score	0.731624 (rank : 21)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UB17L_HUMAN
θ value	4.44505e-15 (rank : 21)	NC score	0.741748 (rank : 20)
Query Neighborhood Hits	149	Target Neighborhood Hits	83	Shared Neighborhood Hits	70
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP22_MOUSE
θ value	4.44505e-15 (rank : 22)	NC score	0.730253 (rank : 22)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
θ value	7.58209e-15 (rank : 23)	NC score	0.729509 (rank : 23)
Query Neighborhood Hits	149	Target Neighborhood Hits	162	Shared Neighborhood Hits	74
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBPW_MOUSE
θ value	9.90251e-15 (rank : 24)	NC score	0.763255 (rank : 15)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP8_HUMAN
θ value	1.29331e-14 (rank : 25)	NC score	0.669239 (rank : 38)
Query Neighborhood Hits	149	Target Neighborhood Hits	751	Shared Neighborhood Hits	84
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP8_MOUSE
θ value	6.41864e-14 (rank : 26)	NC score	0.704101 (rank : 32)
Query Neighborhood Hits	149	Target Neighborhood Hits	362	Shared Neighborhood Hits	79
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP2_HUMAN
θ value	7.09661e-13 (rank : 27)	NC score	0.712767 (rank : 25)
Query Neighborhood Hits	149	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_MOUSE
θ value	9.26847e-13 (rank : 28)	NC score	0.711444 (rank : 27)
Query Neighborhood Hits	149	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP21_HUMAN
θ value	1.58096e-12 (rank : 29)	NC score	0.704580 (rank : 30)
Query Neighborhood Hits	149	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP38_HUMAN
θ value	1.58096e-12 (rank : 30)	NC score	0.652918 (rank : 41)
Query Neighborhood Hits	149	Target Neighborhood Hits	97	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP21_MOUSE
θ value	3.52202e-12 (rank : 31)	NC score	0.702761 (rank : 33)
Query Neighborhood Hits	149	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP38_MOUSE
θ value	3.52202e-12 (rank : 32)	NC score	0.646367 (rank : 42)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP3_HUMAN
θ value	7.84624e-12 (rank : 33)	NC score	0.706532 (rank : 29)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_MOUSE
θ value	7.84624e-12 (rank : 34)	NC score	0.711258 (rank : 28)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP20_HUMAN
θ value	6.64225e-11 (rank : 35)	NC score	0.704145 (rank : 31)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP50_MOUSE
θ value	1.47974e-10 (rank : 36)	NC score	0.711655 (rank : 26)
Query Neighborhood Hits	149	Target Neighborhood Hits	80	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP35_HUMAN
θ value	1.9326e-10 (rank : 37)	NC score	0.681379 (rank : 36)
Query Neighborhood Hits	149	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP5_MOUSE
θ value	5.62301e-10 (rank : 38)	NC score	0.500159 (rank : 61)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP33_HUMAN
θ value	3.64472e-09 (rank : 39)	NC score	0.683049 (rank : 35)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP5_HUMAN
θ value	3.64472e-09 (rank : 40)	NC score	0.497089 (rank : 62)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP44_HUMAN
θ value	2.36244e-08 (rank : 41)	NC score	0.674140 (rank : 37)
Query Neighborhood Hits	149	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_HUMAN
θ value	2.36244e-08 (rank : 42)	NC score	0.666238 (rank : 40)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_MOUSE
θ value	2.36244e-08 (rank : 43)	NC score	0.666946 (rank : 39)
Query Neighborhood Hits	149	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP14_HUMAN
θ value	3.08544e-08 (rank : 44)	NC score	0.626355 (rank : 45)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP11_HUMAN
θ value	6.87365e-08 (rank : 45)	NC score	0.599430 (rank : 46)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP50_HUMAN
θ value	1.17247e-07 (rank : 46)	NC score	0.685327 (rank : 34)
Query Neighborhood Hits	149	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP25_MOUSE
θ value	1.53129e-07 (rank : 47)	NC score	0.494888 (rank : 63)
Query Neighborhood Hits	149	Target Neighborhood Hits	116	Shared Neighborhood Hits	70
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP28_HUMAN
θ value	1.53129e-07 (rank : 48)	NC score	0.508630 (rank : 59)
Query Neighborhood Hits	149	Target Neighborhood Hits	117	Shared Neighborhood Hits	70
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP37_HUMAN
θ value	1.53129e-07 (rank : 49)	NC score	0.565076 (rank : 56)
Query Neighborhood Hits	149	Target Neighborhood Hits	208	Shared Neighborhood Hits	77
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP25_HUMAN
θ value	1.99992e-07 (rank : 50)	NC score	0.491565 (rank : 64)
Query Neighborhood Hits	149	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP28_MOUSE
θ value	3.41135e-07 (rank : 51)	NC score	0.505165 (rank : 60)
Query Neighborhood Hits	149	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP15_HUMAN
θ value	1.29631e-06 (rank : 52)	NC score	0.593485 (rank : 49)
Query Neighborhood Hits	149	Target Neighborhood Hits	92	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	1.29631e-06 (rank : 53)	NC score	0.593511 (rank : 48)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP4_HUMAN
θ value	1.29631e-06 (rank : 54)	NC score	0.580835 (rank : 53)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP14_MOUSE
θ value	1.69304e-06 (rank : 55)	NC score	0.594966 (rank : 47)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP1_HUMAN
θ value	2.88788e-06 (rank : 56)	NC score	0.635695 (rank : 43)
Query Neighborhood Hits	149	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP31_HUMAN
θ value	3.77169e-06 (rank : 57)	NC score	0.589904 (rank : 51)
Query Neighborhood Hits	149	Target Neighborhood Hits	293	Shared Neighborhood Hits	72
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP43_MOUSE
θ value	6.43352e-06 (rank : 58)	NC score	0.590076 (rank : 50)
Query Neighborhood Hits	149	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP32_HUMAN
θ value	2.44474e-05 (rank : 59)	NC score	0.491486 (rank : 65)
Query Neighborhood Hits	149	Target Neighborhood Hits	170	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP43_HUMAN
θ value	2.44474e-05 (rank : 60)	NC score	0.581687 (rank : 52)
Query Neighborhood Hits	149	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP29_MOUSE
θ value	4.1701e-05 (rank : 61)	NC score	0.476370 (rank : 67)
Query Neighborhood Hits	149	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP29_HUMAN
θ value	0.000158464 (rank : 62)	NC score	0.484494 (rank : 66)
Query Neighborhood Hits	149	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP6_HUMAN
θ value	0.00035302 (rank : 63)	NC score	0.459603 (rank : 69)
Query Neighborhood Hits	149	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP10_HUMAN
θ value	0.000461057 (rank : 64)	NC score	0.540227 (rank : 57)
Query Neighborhood Hits	149	Target Neighborhood Hits	153	Shared Neighborhood Hits	70
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP13_HUMAN
θ value	0.000461057 (rank : 65)	NC score	0.469074 (rank : 68)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	71
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP26_MOUSE
θ value	0.000602161 (rank : 66)	NC score	0.398724 (rank : 72)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP4_MOUSE
θ value	0.000602161 (rank : 67)	NC score	0.575642 (rank : 55)
Query Neighborhood Hits	149	Target Neighborhood Hits	90	Shared Neighborhood Hits	71
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP16_HUMAN
θ value	0.00175202 (rank : 68)	NC score	0.627468 (rank : 44)
Query Neighborhood Hits	149	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP30_HUMAN
θ value	0.00175202 (rank : 69)	NC score	0.576747 (rank : 54)
Query Neighborhood Hits	149	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP10_MOUSE
θ value	0.00390308 (rank : 70)	NC score	0.538127 (rank : 58)
Query Neighborhood Hits	149	Target Neighborhood Hits	150	Shared Neighborhood Hits	68
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

ASXL1_MOUSE
θ value	0.0330416 (rank : 71)	NC score	0.081682 (rank : 74)
Query Neighborhood Hits	149	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ASXL1_HUMAN
θ value	0.0431538 (rank : 72)	NC score	0.080225 (rank : 75)
Query Neighborhood Hits	149	Target Neighborhood Hits	260	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CCNB3_MOUSE
θ value	0.0431538 (rank : 73)	NC score	0.035620 (rank : 92)
Query Neighborhood Hits	149	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

SAFB1_HUMAN
θ value	0.0961366 (rank : 74)	NC score	0.037302 (rank : 90)
Query Neighborhood Hits	149	Target Neighborhood Hits	493	Shared Neighborhood Hits	13
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

UBP26_HUMAN
θ value	0.0961366 (rank : 75)	NC score	0.436038 (rank : 70)
Query Neighborhood Hits	149	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

ATRX_MOUSE
θ value	0.125558 (rank : 76)	NC score	0.027082 (rank : 97)
Query Neighborhood Hits	149	Target Neighborhood Hits	682	Shared Neighborhood Hits	29
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SPT6H_HUMAN
θ value	0.163984 (rank : 77)	NC score	0.063136 (rank : 78)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	9
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SPT6H_MOUSE
θ value	0.163984 (rank : 78)	NC score	0.062651 (rank : 79)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

LEO1_HUMAN
θ value	0.21417 (rank : 79)	NC score	0.043821 (rank : 87)
Query Neighborhood Hits	149	Target Neighborhood Hits	958	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DLG4_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.018125 (rank : 108)
Query Neighborhood Hits	149	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	0.47712 (rank : 81)	NC score	0.018164 (rank : 107)
Query Neighborhood Hits	149	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

TREX2_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.043498 (rank : 88)
Query Neighborhood Hits	149	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQ50, Q45F08, Q9UN77	Gene names	TREX2
Domain Architecture
Description	Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2).

FA21C_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.043231 (rank : 89)
Query Neighborhood Hits	149	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

ATAD2_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.010481 (rank : 122)
Query Neighborhood Hits	149	Target Neighborhood Hits	322	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

RYR2_HUMAN
θ value	0.813845 (rank : 85)	NC score	0.022298 (rank : 101)
Query Neighborhood Hits	149	Target Neighborhood Hits	175	Shared Neighborhood Hits	5
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

TXND2_MOUSE
θ value	0.813845 (rank : 86)	NC score	0.028810 (rank : 94)
Query Neighborhood Hits	149	Target Neighborhood Hits	828	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

DLG1_MOUSE
θ value	1.06291 (rank : 87)	NC score	0.017288 (rank : 111)
Query Neighborhood Hits	149	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

EMIL2_MOUSE
θ value	1.06291 (rank : 88)	NC score	0.018104 (rank : 109)
Query Neighborhood Hits	149	Target Neighborhood Hits	485	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

MGR4_HUMAN
θ value	1.06291 (rank : 89)	NC score	0.011176 (rank : 120)
Query Neighborhood Hits	149	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

PTN13_HUMAN
θ value	1.06291 (rank : 90)	NC score	0.013392 (rank : 118)
Query Neighborhood Hits	149	Target Neighborhood Hits	471	Shared Neighborhood Hits	18
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

DLG1_HUMAN
θ value	1.38821 (rank : 91)	NC score	0.016874 (rank : 112)
Query Neighborhood Hits	149	Target Neighborhood Hits	290	Shared Neighborhood Hits	8
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DMP1_HUMAN
θ value	1.38821 (rank : 92)	NC score	0.048053 (rank : 85)
Query Neighborhood Hits	149	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

OSBL8_HUMAN
θ value	1.38821 (rank : 93)	NC score	0.021950 (rank : 104)
Query Neighborhood Hits	149	Target Neighborhood Hits	289	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

SQSTM_MOUSE
θ value	1.38821 (rank : 94)	NC score	0.027977 (rank : 95)
Query Neighborhood Hits	149	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q64337, Q99JM8	Gene names	Sqstm1, A170, STAP
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Ubiquitin-binding protein p62) (STONE14).

TOP3A_MOUSE
θ value	1.38821 (rank : 95)	NC score	0.016057 (rank : 114)
Query Neighborhood Hits	149	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

UBP53_MOUSE
θ value	1.38821 (rank : 96)	NC score	0.062432 (rank : 80)
Query Neighborhood Hits	149	Target Neighborhood Hits	188	Shared Neighborhood Hits	23
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

GAGC1_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.022004 (rank : 103)
Query Neighborhood Hits	149	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	O60829, Q6IBI1	Gene names	PAGE4, GAGEC1
Domain Architecture
Description	G antigen family C member 1 (Prostate-associated gene 4 protein) (PAGE-4) (PAGE-1) (GAGE-9).

STON1_MOUSE
θ value	1.81305 (rank : 98)	NC score	0.022233 (rank : 102)
Query Neighborhood Hits	149	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

ZN583_HUMAN
θ value	1.81305 (rank : 99)	NC score	-0.003417 (rank : 151)
Query Neighborhood Hits	149	Target Neighborhood Hits	774	Shared Neighborhood Hits	7
SwissProt Accessions	Q96ND8, O14850, Q2NKK3	Gene names	ZNF583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583 (Zinc finger protein L3-5).

CTGE5_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.010126 (rank : 125)
Query Neighborhood Hits	149	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

FBX30_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.023488 (rank : 99)
Query Neighborhood Hits	149	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB52, Q9BXZ7	Gene names	FBXO30, FBX30
Domain Architecture
Description	F-box only protein 30.

LEO1_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.036054 (rank : 91)
Query Neighborhood Hits	149	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

N4BP2_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.022451 (rank : 100)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

NEK8_MOUSE
θ value	2.36792 (rank : 104)	NC score	-0.003106 (rank : 150)
Query Neighborhood Hits	149	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZR4, Q3U498, Q9D685	Gene names	Nek8, Jck
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8).

TREX2_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.027687 (rank : 96)
Query Neighborhood Hits	149	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1A9	Gene names	Trex2
Domain Architecture
Description	Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2).

DBF4_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.020898 (rank : 106)
Query Neighborhood Hits	149	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ41, Q3TQP4, Q3V1K2, Q6NSQ1, Q9CXF2	Gene names	Dbf4
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (MuDBF4).

DSPP_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.043906 (rank : 86)
Query Neighborhood Hits	149	Target Neighborhood Hits	645	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

K1H2_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.002851 (rank : 139)
Query Neighborhood Hits	149	Target Neighborhood Hits	446	Shared Neighborhood Hits	11
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

MYH14_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.000081 (rank : 146)
Query Neighborhood Hits	149	Target Neighborhood Hits	995	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NEK8_HUMAN
θ value	3.0926 (rank : 110)	NC score	-0.003436 (rank : 152)
Query Neighborhood Hits	149	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

TRPC7_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.007521 (rank : 127)
Query Neighborhood Hits	149	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

ZN518_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.000073 (rank : 147)
Query Neighborhood Hits	149	Target Neighborhood Hits	780	Shared Neighborhood Hits	9
SwissProt Accessions	Q6AHZ1, O15044, Q32MP4	Gene names	ZNF518, KIAA0335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 518.

DEK_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.034728 (rank : 93)
Query Neighborhood Hits	149	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DSPP_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.049679 (rank : 84)
Query Neighborhood Hits	149	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MYEF2_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.010160 (rank : 124)
Query Neighborhood Hits	149	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2K5, Q6NUM5, Q7L388, Q7Z4B7, Q9H922, Q9NUQ1	Gene names	MYEF2, KIAA1341
Domain Architecture	No domain graphic available
Description	Myelin expression factor 2 (MyEF-2) (MST156).

PLEC1_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.001745 (rank : 143)
Query Neighborhood Hits	149	Target Neighborhood Hits	1326	Shared Neighborhood Hits	19
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

ATL2_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.003339 (rank : 135)
Query Neighborhood Hits	149	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

BNIP2_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.016699 (rank : 113)
Query Neighborhood Hits	149	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

CK5P2_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.003337 (rank : 136)
Query Neighborhood Hits	149	Target Neighborhood Hits	1433	Shared Neighborhood Hits	27
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CT172_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.024987 (rank : 98)
Query Neighborhood Hits	149	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYC5, Q9CYF2, Q9DA26	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172 homolog.

K1H2_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.002010 (rank : 142)
Query Neighborhood Hits	149	Target Neighborhood Hits	492	Shared Neighborhood Hits	12
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

KV2A_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.003347 (rank : 134)
Query Neighborhood Hits	149	Target Neighborhood Hits	262	Shared Neighborhood Hits	5
SwissProt Accessions	P01626	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-II region MOPC 167.

KV2E_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.005197 (rank : 132)
Query Neighborhood Hits	149	Target Neighborhood Hits	253	Shared Neighborhood Hits	5
SwissProt Accessions	P03976	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-II region 17S29.1.

TAF1_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.012828 (rank : 119)
Query Neighborhood Hits	149	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TRAF5_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.005462 (rank : 131)
Query Neighborhood Hits	149	Target Neighborhood Hits	396	Shared Neighborhood Hits	13
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

ZN431_HUMAN
θ value	5.27518 (rank : 126)	NC score	-0.004100 (rank : 153)
Query Neighborhood Hits	149	Target Neighborhood Hits	765	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TF32, Q8IWC4	Gene names	ZNF431, KIAA1969
Domain Architecture
Description	Zinc finger protein 431.

ZPI_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.002866 (rank : 138)
Query Neighborhood Hits	149	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R121, Q8VCV8	Gene names	Serpina10, Zpi
Domain Architecture	No domain graphic available
Description	Protein Z-dependent protease inhibitor precursor (PZ-dependent protease inhibitor) (PZI) (Serpin A10).

AKAP2_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.010200 (rank : 123)
Query Neighborhood Hits	149	Target Neighborhood Hits	507	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

EP15R_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.002108 (rank : 141)
Query Neighborhood Hits	149	Target Neighborhood Hits	1083	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

GSTT2_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.015438 (rank : 115)
Query Neighborhood Hits	149	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q61133, Q61134, Q64472	Gene names	Gstt2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

K1H1_MOUSE
θ value	6.88961 (rank : 131)	NC score	0.002127 (rank : 140)
Query Neighborhood Hits	149	Target Neighborhood Hits	450	Shared Neighborhood Hits	11
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

NP1L3_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.021464 (rank : 105)
Query Neighborhood Hits	149	Target Neighborhood Hits	233	Shared Neighborhood Hits	14
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

R51A1_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.017329 (rank : 110)
Query Neighborhood Hits	149	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

SGCG_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.013537 (rank : 117)
Query Neighborhood Hits	149	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q13326	Gene names	SGCG
Domain Architecture
Description	Gamma-sarcoglycan (Gamma-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG).

AP3B1_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.010701 (rank : 121)
Query Neighborhood Hits	149	Target Neighborhood Hits	302	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CP135_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.000009 (rank : 148)
Query Neighborhood Hits	149	Target Neighborhood Hits	1290	Shared Neighborhood Hits	18
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DDX24_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.001089 (rank : 145)
Query Neighborhood Hits	149	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

EEA1_HUMAN
θ value	8.99809 (rank : 138)	NC score	-0.001472 (rank : 149)
Query Neighborhood Hits	149	Target Neighborhood Hits	1796	Shared Neighborhood Hits	25
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GBA3_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.004826 (rank : 133)
Query Neighborhood Hits	149	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).

GCP5_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.014392 (rank : 116)
Query Neighborhood Hits	149	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RT8, Q96PY8	Gene names	TUBGCP5, GCP5, KIAA1899
Domain Architecture
Description	Gamma-tubulin complex component 5 (GCP-5).

KV2B_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.002932 (rank : 137)
Query Neighborhood Hits	149	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	P01627	Gene names
Domain Architecture
Description	Ig kappa chain V-II region VKappa167 precursor.

PKP4_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.006483 (rank : 129)
Query Neighborhood Hits	149	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

STX7_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.007341 (rank : 128)
Query Neighborhood Hits	149	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	O15400, Q5SZW2, Q96ES9	Gene names	STX7
Domain Architecture
Description	Syntaxin-7.

STX7_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.009177 (rank : 126)
Query Neighborhood Hits	149	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	O70439	Gene names	Stx7, Syn7
Domain Architecture
Description	Syntaxin-7.

TDRD7_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.006217 (rank : 130)
Query Neighborhood Hits	149	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHU6, Q96JT1, Q9UFF0, Q9Y2M3	Gene names	TDRD7, PCTAIRE2BP
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

TITIN_HUMAN
θ value	8.99809 (rank : 146)	NC score	-0.005827 (rank : 156)
Query Neighborhood Hits	149	Target Neighborhood Hits	2923	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRIPB_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.001144 (rank : 144)
Query Neighborhood Hits	149	Target Neighborhood Hits	1587	Shared Neighborhood Hits	29
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ZN583_MOUSE
θ value	8.99809 (rank : 148)	NC score	-0.004419 (rank : 154)
Query Neighborhood Hits	149	Target Neighborhood Hits	774	Shared Neighborhood Hits	7
SwissProt Accessions	Q3V080, Q3V3L4	Gene names	Znf583, Zfp583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583.

ZNF85_HUMAN
θ value	8.99809 (rank : 149)	NC score	-0.004544 (rank : 155)
Query Neighborhood Hits	149	Target Neighborhood Hits	770	Shared Neighborhood Hits	7
SwissProt Accessions	Q03923	Gene names	ZNF85
Domain Architecture
Description	Zinc finger protein 85 (Zinc finger protein HPF4) (HTF1).

BRAP_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.063459 (rank : 77)
Query Neighborhood Hits	149	Target Neighborhood Hits	560	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.072601 (rank : 76)
Query Neighborhood Hits	149	Target Neighborhood Hits	409	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

SNUT2_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.392854 (rank : 73)
Query Neighborhood Hits	149	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.405418 (rank : 71)
Query Neighborhood Hits	149	Target Neighborhood Hits	80	Shared Neighborhood Hits	58
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP53_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.051101 (rank : 83)
Query Neighborhood Hits	149	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP54_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.055938 (rank : 81)
Query Neighborhood Hits	149	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.055632 (rank : 82)
Query Neighborhood Hits	149	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

Hits sorted by NC score

UBP47_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	149	Target Neighborhood Hits	149	Shared Neighborhood Hits	149
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_MOUSE
NC score	0.995727 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	149	Target Neighborhood Hits	135	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP7_HUMAN
NC score	0.876781 (rank : 3)	θ value	1.41672e-45 (rank : 3)
Query Neighborhood Hits	149	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP40_HUMAN
NC score	0.861892 (rank : 4)	θ value	4.41421e-39 (rank : 4)
Query Neighborhood Hits	149	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP18_HUMAN
NC score	0.856857 (rank : 5)	θ value	2.50655e-34 (rank : 6)
Query Neighborhood Hits	149	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP48_HUMAN
NC score	0.839317 (rank : 6)	θ value	5.96599e-36 (rank : 5)
Query Neighborhood Hits	149	Target Neighborhood Hits	101	Shared Neighborhood Hits	72
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.832109 (rank : 7)	θ value	1.52067e-31 (rank : 8)
Query Neighborhood Hits	149	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP18_MOUSE
NC score	0.828521 (rank : 8)	θ value	3.50572e-28 (rank : 14)
Query Neighborhood Hits	149	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP24_HUMAN
NC score	0.823503 (rank : 9)	θ value	6.82597e-32 (rank : 7)
Query Neighborhood Hits	149	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP12_HUMAN
NC score	0.790106 (rank : 10)	θ value	2.69047e-20 (rank : 15)
Query Neighborhood Hits	149	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP46_HUMAN
NC score	0.787479 (rank : 11)	θ value	8.10077e-17 (rank : 17)
Query Neighborhood Hits	149	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.787479 (rank : 12)	θ value	8.10077e-17 (rank : 18)
Query Neighborhood Hits	149	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP34_HUMAN
NC score	0.771259 (rank : 13)	θ value	8.3442e-30 (rank : 11)
Query Neighborhood Hits	149	Target Neighborhood Hits	210	Shared Neighborhood Hits	77
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
NC score	0.771126 (rank : 14)	θ value	1.2049e-28 (rank : 13)
Query Neighborhood Hits	149	Target Neighborhood Hits	189	Shared Neighborhood Hits	76
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBPW_MOUSE
NC score	0.763255 (rank : 15)	θ value	9.90251e-15 (rank : 24)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

USP9Y_HUMAN
NC score	0.763105 (rank : 16)	θ value	3.3877e-31 (rank : 9)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP36_HUMAN
NC score	0.758303 (rank : 17)	θ value	1.02238e-19 (rank : 16)
Query Neighborhood Hits	149	Target Neighborhood Hits	232	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

USP9X_HUMAN
NC score	0.754386 (rank : 18)	θ value	5.40856e-29 (rank : 12)
Query Neighborhood Hits	149	Target Neighborhood Hits	161	Shared Neighborhood Hits	72
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.753572 (rank : 19)	θ value	4.89182e-30 (rank : 10)
Query Neighborhood Hits	149	Target Neighborhood Hits	171	Shared Neighborhood Hits	72
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UB17L_HUMAN
NC score	0.741748 (rank : 20)	θ value	4.44505e-15 (rank : 21)
Query Neighborhood Hits	149	Target Neighborhood Hits	83	Shared Neighborhood Hits	70
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP22_HUMAN
NC score	0.731624 (rank : 21)	θ value	2.60593e-15 (rank : 20)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
NC score	0.730253 (rank : 22)	θ value	4.44505e-15 (rank : 22)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.729509 (rank : 23)	θ value	7.58209e-15 (rank : 23)
Query Neighborhood Hits	149	Target Neighborhood Hits	162	Shared Neighborhood Hits	74
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP42_HUMAN
NC score	0.718962 (rank : 24)	θ value	1.80466e-16 (rank : 19)
Query Neighborhood Hits	149	Target Neighborhood Hits	445	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP2_HUMAN
NC score	0.712767 (rank : 25)	θ value	7.09661e-13 (rank : 27)
Query Neighborhood Hits	149	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP50_MOUSE
NC score	0.711655 (rank : 26)	θ value	1.47974e-10 (rank : 36)
Query Neighborhood Hits	149	Target Neighborhood Hits	80	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP2_MOUSE
NC score	0.711444 (rank : 27)	θ value	9.26847e-13 (rank : 28)
Query Neighborhood Hits	149	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP3_MOUSE
NC score	0.711258 (rank : 28)	θ value	7.84624e-12 (rank : 34)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_HUMAN
NC score	0.706532 (rank : 29)	θ value	7.84624e-12 (rank : 33)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP21_HUMAN
NC score	0.704580 (rank : 30)	θ value	1.58096e-12 (rank : 29)
Query Neighborhood Hits	149	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP20_HUMAN
NC score	0.704145 (rank : 31)	θ value	6.64225e-11 (rank : 35)
Query Neighborhood Hits	149	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP8_MOUSE
NC score	0.704101 (rank : 32)	θ value	6.41864e-14 (rank : 26)
Query Neighborhood Hits	149	Target Neighborhood Hits	362	Shared Neighborhood Hits	79
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP21_MOUSE
NC score	0.702761 (rank : 33)	θ value	3.52202e-12 (rank : 31)
Query Neighborhood Hits	149	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP50_HUMAN
NC score	0.685327 (rank : 34)	θ value	1.17247e-07 (rank : 46)
Query Neighborhood Hits	149	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP33_HUMAN
NC score	0.683049 (rank : 35)	θ value	3.64472e-09 (rank : 39)
Query Neighborhood Hits	149	Target Neighborhood Hits	157	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP35_HUMAN
NC score	0.681379 (rank : 36)	θ value	1.9326e-10 (rank : 37)
Query Neighborhood Hits	149	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP44_HUMAN
NC score	0.674140 (rank : 37)	θ value	2.36244e-08 (rank : 41)
Query Neighborhood Hits	149	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP8_HUMAN
NC score	0.669239 (rank : 38)	θ value	1.29331e-14 (rank : 25)
Query Neighborhood Hits	149	Target Neighborhood Hits	751	Shared Neighborhood Hits	84
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP49_MOUSE
NC score	0.666946 (rank : 39)	θ value	2.36244e-08 (rank : 43)
Query Neighborhood Hits	149	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_HUMAN
NC score	0.666238 (rank : 40)	θ value	2.36244e-08 (rank : 42)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP38_HUMAN
NC score	0.652918 (rank : 41)	θ value	1.58096e-12 (rank : 30)
Query Neighborhood Hits	149	Target Neighborhood Hits	97	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
NC score	0.646367 (rank : 42)	θ value	3.52202e-12 (rank : 32)
Query Neighborhood Hits	149	Target Neighborhood Hits	100	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP1_HUMAN
NC score	0.635695 (rank : 43)	θ value	2.88788e-06 (rank : 56)
Query Neighborhood Hits	149	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP16_HUMAN
NC score	0.627468 (rank : 44)	θ value	0.00175202 (rank : 68)
Query Neighborhood Hits	149	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP14_HUMAN
NC score	0.626355 (rank : 45)	θ value	3.08544e-08 (rank : 44)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP11_HUMAN
NC score	0.599430 (rank : 46)	θ value	6.87365e-08 (rank : 45)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP14_MOUSE
NC score	0.594966 (rank : 47)	θ value	1.69304e-06 (rank : 55)
Query Neighborhood Hits	149	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP15_MOUSE
NC score	0.593511 (rank : 48)	θ value	1.29631e-06 (rank : 53)
Query Neighborhood Hits	149	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP15_HUMAN
NC score	0.593485 (rank : 49)	θ value	1.29631e-06 (rank : 52)
Query Neighborhood Hits	149	Target Neighborhood Hits	92	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP43_MOUSE
NC score	0.590076 (rank : 50)	θ value	6.43352e-06 (rank : 58)
Query Neighborhood Hits	149	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP31_HUMAN
NC score	0.589904 (rank : 51)	θ value	3.77169e-06 (rank : 57)
Query Neighborhood Hits	149	Target Neighborhood Hits	293	Shared Neighborhood Hits	72
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP43_HUMAN
NC score	0.581687 (rank : 52)	θ value	2.44474e-05 (rank : 60)
Query Neighborhood Hits	149	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP4_HUMAN
NC score	0.580835 (rank : 53)	θ value	1.29631e-06 (rank : 54)
Query Neighborhood Hits	149	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP30_HUMAN
NC score	0.576747 (rank : 54)	θ value	0.00175202 (rank : 69)
Query Neighborhood Hits	149	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP4_MOUSE
NC score	0.575642 (rank : 55)	θ value	0.000602161 (rank : 67)
Query Neighborhood Hits	149	Target Neighborhood Hits	90	Shared Neighborhood Hits	71
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP37_HUMAN
NC score	0.565076 (rank : 56)	θ value	1.53129e-07 (rank : 49)
Query Neighborhood Hits	149	Target Neighborhood Hits	208	Shared Neighborhood Hits	77
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP10_HUMAN
NC score	0.540227 (rank : 57)	θ value	0.000461057 (rank : 64)
Query Neighborhood Hits	149	Target Neighborhood Hits	153	Shared Neighborhood Hits	70
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_MOUSE
NC score	0.538127 (rank : 58)	θ value	0.00390308 (rank : 70)
Query Neighborhood Hits	149	Target Neighborhood Hits	150	Shared Neighborhood Hits	68
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP28_HUMAN
NC score	0.508630 (rank : 59)	θ value	1.53129e-07 (rank : 48)
Query Neighborhood Hits	149	Target Neighborhood Hits	117	Shared Neighborhood Hits	70
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_MOUSE
NC score	0.505165 (rank : 60)	θ value	3.41135e-07 (rank : 51)
Query Neighborhood Hits	149	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP5_MOUSE
NC score	0.500159 (rank : 61)	θ value	5.62301e-10 (rank : 38)
Query Neighborhood Hits	149	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_HUMAN
NC score	0.497089 (rank : 62)	θ value	3.64472e-09 (rank : 40)
Query Neighborhood Hits	149	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP25_MOUSE
NC score	0.494888 (rank : 63)	θ value	1.53129e-07 (rank : 47)
Query Neighborhood Hits	149	Target Neighborhood Hits	116	Shared Neighborhood Hits	70
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.491565 (rank : 64)	θ value	1.99992e-07 (rank : 50)
Query Neighborhood Hits	149	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP32_HUMAN
NC score	0.491486 (rank : 65)	θ value	2.44474e-05 (rank : 59)
Query Neighborhood Hits	149	Target Neighborhood Hits	170	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP29_HUMAN
NC score	0.484494 (rank : 66)	θ value	0.000158464 (rank : 62)
Query Neighborhood Hits	149	Target Neighborhood Hits	94	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP29_MOUSE
NC score	0.476370 (rank : 67)	θ value	4.1701e-05 (rank : 61)
Query Neighborhood Hits	149	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP13_HUMAN
NC score	0.469074 (rank : 68)	θ value	0.000461057 (rank : 65)
Query Neighborhood Hits	149	Target Neighborhood Hits	99	Shared Neighborhood Hits	71
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP6_HUMAN
NC score	0.459603 (rank : 69)	θ value	0.00035302 (rank : 63)
Query Neighborhood Hits	149	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP26_HUMAN
NC score	0.436038 (rank : 70)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	149	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

SNUT2_MOUSE
NC score	0.405418 (rank : 71)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	149	Target Neighborhood Hits	80	Shared Neighborhood Hits	58
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP26_MOUSE
NC score	0.398724 (rank : 72)	θ value	0.000602161 (rank : 66)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

SNUT2_HUMAN
NC score	0.392854 (rank : 73)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	149	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

ASXL1_MOUSE
NC score	0.081682 (rank : 74)	θ value	0.0330416 (rank : 71)
Query Neighborhood Hits	149	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ASXL1_HUMAN
NC score	0.080225 (rank : 75)	θ value	0.0431538 (rank : 72)
Query Neighborhood Hits	149	Target Neighborhood Hits	260	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BRAP_MOUSE
NC score	0.072601 (rank : 76)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	149	Target Neighborhood Hits	409	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRAP_HUMAN
NC score	0.063459 (rank : 77)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	149	Target Neighborhood Hits	560	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

SPT6H_HUMAN
NC score	0.063136 (rank : 78)	θ value	0.163984 (rank : 77)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	9
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SPT6H_MOUSE
NC score	0.062651 (rank : 79)	θ value	0.163984 (rank : 78)
Query Neighborhood Hits	149	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

UBP53_MOUSE
NC score	0.062432 (rank : 80)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	149	Target Neighborhood Hits	188	Shared Neighborhood Hits	23
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP54_HUMAN
NC score	0.055938 (rank : 81)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	149	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_MOUSE
NC score	0.055632 (rank : 82)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	149	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP53_HUMAN
NC score	0.051101 (rank : 83)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	149	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

DSPP_MOUSE
NC score	0.049679 (rank : 84)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	149	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DMP1_HUMAN
NC score	0.048053 (rank : 85)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	149	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DSPP_HUMAN
NC score	0.043906 (rank : 86)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	149	Target Neighborhood Hits	645	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_HUMAN
NC score	0.043821 (rank : 87)	θ value	0.21417 (rank : 79)
Query Neighborhood Hits	149	Target Neighborhood Hits	958	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

TREX2_HUMAN
NC score	0.043498 (rank : 88)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	149	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQ50, Q45F08, Q9UN77	Gene names	TREX2
Domain Architecture
Description	Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2).

FA21C_HUMAN
NC score	0.043231 (rank : 89)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	149	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

SAFB1_HUMAN
NC score	0.037302 (rank : 90)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	149	Target Neighborhood Hits	493	Shared Neighborhood Hits	13
SwissProt Accessions	Q15424, O60406, Q59HH8	Gene names	SAFB, HAP, HET, SAFB1
Domain Architecture
Description	Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE- TATA-binding protein).

LEO1_MOUSE
NC score	0.036054 (rank : 91)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	149	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

CCNB3_MOUSE
NC score	0.035620 (rank : 92)	θ value	0.0431538 (rank : 73)
Query Neighborhood Hits	149	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

DEK_MOUSE
NC score	0.034728 (rank : 93)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	149	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

TXND2_MOUSE
NC score	0.028810 (rank : 94)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	149	Target Neighborhood Hits	828	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

SQSTM_MOUSE
NC score	0.027977 (rank : 95)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	149	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q64337, Q99JM8	Gene names	Sqstm1, A170, STAP
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Ubiquitin-binding protein p62) (STONE14).

TREX2_MOUSE
NC score	0.027687 (rank : 96)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	149	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1A9	Gene names	Trex2
Domain Architecture
Description	Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2).

ATRX_MOUSE
NC score	0.027082 (rank : 97)	θ value	0.125558 (rank : 76)
Query Neighborhood Hits	149	Target Neighborhood Hits	682	Shared Neighborhood Hits	29
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CT172_MOUSE
NC score	0.024987 (rank : 98)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	149	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CYC5, Q9CYF2, Q9DA26	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172 homolog.

FBX30_HUMAN
NC score	0.023488 (rank : 99)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	149	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB52, Q9BXZ7	Gene names	FBXO30, FBX30
Domain Architecture
Description	F-box only protein 30.

N4BP2_HUMAN
NC score	0.022451 (rank : 100)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	149	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

RYR2_HUMAN
NC score	0.022298 (rank : 101)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	149	Target Neighborhood Hits	175	Shared Neighborhood Hits	5
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

STON1_MOUSE
NC score	0.022233 (rank : 102)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	149	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

GAGC1_HUMAN
NC score	0.022004 (rank : 103)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	149	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	O60829, Q6IBI1	Gene names	PAGE4, GAGEC1
Domain Architecture
Description	G antigen family C member 1 (Prostate-associated gene 4 protein) (PAGE-4) (PAGE-1) (GAGE-9).

OSBL8_HUMAN
NC score	0.021950 (rank : 104)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	149	Target Neighborhood Hits	289	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

NP1L3_MOUSE
NC score	0.021464 (rank : 105)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	149	Target Neighborhood Hits	233	Shared Neighborhood Hits	14
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

DBF4_MOUSE
NC score	0.020898 (rank : 106)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	149	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ41, Q3TQP4, Q3V1K2, Q6NSQ1, Q9CXF2	Gene names	Dbf4
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (MuDBF4).

DLG4_MOUSE
NC score	0.018164 (rank : 107)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	149	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.018125 (rank : 108)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	149	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

EMIL2_MOUSE
NC score	0.018104 (rank : 109)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	149	Target Neighborhood Hits	485	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

R51A1_MOUSE
NC score	0.017329 (rank : 110)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	149	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

DLG1_MOUSE
NC score	0.017288 (rank : 111)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	149	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG1_HUMAN
NC score	0.016874 (rank : 112)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	149	Target Neighborhood Hits	290	Shared Neighborhood Hits	8
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

BNIP2_MOUSE
NC score	0.016699 (rank : 113)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	149	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

TOP3A_MOUSE
NC score	0.016057 (rank : 114)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	149	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

GSTT2_MOUSE
NC score	0.015438 (rank : 115)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	149	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q61133, Q61134, Q64472	Gene names	Gstt2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

GCP5_HUMAN
NC score	0.014392 (rank : 116)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	149	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RT8, Q96PY8	Gene names	TUBGCP5, GCP5, KIAA1899
Domain Architecture
Description	Gamma-tubulin complex component 5 (GCP-5).

SGCG_HUMAN
NC score	0.013537 (rank : 117)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	149	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q13326	Gene names	SGCG
Domain Architecture
Description	Gamma-sarcoglycan (Gamma-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG).

PTN13_HUMAN
NC score	0.013392 (rank : 118)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	149	Target Neighborhood Hits	471	Shared Neighborhood Hits	18
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

TAF1_HUMAN
NC score	0.012828 (rank : 119)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	149	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

MGR4_HUMAN
NC score	0.011176 (rank : 120)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	149	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

AP3B1_MOUSE
NC score	0.010701 (rank : 121)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	149	Target Neighborhood Hits	302	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ATAD2_HUMAN
NC score	0.010481 (rank : 122)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	149	Target Neighborhood Hits	322	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

AKAP2_HUMAN
NC score	0.010200 (rank : 123)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	149	Target Neighborhood Hits	507	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MYEF2_HUMAN
NC score	0.010160 (rank : 124)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	149	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2K5, Q6NUM5, Q7L388, Q7Z4B7, Q9H922, Q9NUQ1	Gene names	MYEF2, KIAA1341
Domain Architecture	No domain graphic available
Description	Myelin expression factor 2 (MyEF-2) (MST156).

CTGE5_HUMAN
NC score	0.010126 (rank : 125)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	149	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

STX7_MOUSE
NC score	0.009177 (rank : 126)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	149	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	O70439	Gene names	Stx7, Syn7
Domain Architecture
Description	Syntaxin-7.

TRPC7_HUMAN
NC score	0.007521 (rank : 127)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	149	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

STX7_HUMAN
NC score	0.007341 (rank : 128)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	149	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	O15400, Q5SZW2, Q96ES9	Gene names	STX7
Domain Architecture
Description	Syntaxin-7.

PKP4_MOUSE
NC score	0.006483 (rank : 129)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	149	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

TDRD7_HUMAN
NC score	0.006217 (rank : 130)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	149	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHU6, Q96JT1, Q9UFF0, Q9Y2M3	Gene names	TDRD7, PCTAIRE2BP
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

TRAF5_HUMAN
NC score	0.005462 (rank : 131)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	149	Target Neighborhood Hits	396	Shared Neighborhood Hits	13
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

KV2E_MOUSE
NC score	0.005197 (rank : 132)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	149	Target Neighborhood Hits	253	Shared Neighborhood Hits	5
SwissProt Accessions	P03976	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-II region 17S29.1.

GBA3_HUMAN
NC score	0.004826 (rank : 133)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	149	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).

KV2A_MOUSE
NC score	0.003347 (rank : 134)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	149	Target Neighborhood Hits	262	Shared Neighborhood Hits	5
SwissProt Accessions	P01626	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-II region MOPC 167.

ATL2_MOUSE
NC score	0.003339 (rank : 135)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	149	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

CK5P2_HUMAN
NC score	0.003337 (rank : 136)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	149	Target Neighborhood Hits	1433	Shared Neighborhood Hits	27
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

KV2B_MOUSE
NC score	0.002932 (rank : 137)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	149	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	P01627	Gene names
Domain Architecture
Description	Ig kappa chain V-II region VKappa167 precursor.

ZPI_MOUSE
NC score	0.002866 (rank : 138)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	149	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R121, Q8VCV8	Gene names	Serpina10, Zpi
Domain Architecture	No domain graphic available
Description	Protein Z-dependent protease inhibitor precursor (PZ-dependent protease inhibitor) (PZI) (Serpin A10).

K1H2_MOUSE
NC score	0.002851 (rank : 139)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	149	Target Neighborhood Hits	446	Shared Neighborhood Hits	11
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

K1H1_MOUSE
NC score	0.002127 (rank : 140)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	149	Target Neighborhood Hits	450	Shared Neighborhood Hits	11
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

EP15R_HUMAN
NC score	0.002108 (rank : 141)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	149	Target Neighborhood Hits	1083	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

K1H2_HUMAN
NC score	0.002010 (rank : 142)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	149	Target Neighborhood Hits	492	Shared Neighborhood Hits	12
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

PLEC1_HUMAN
NC score	0.001745 (rank : 143)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	149	Target Neighborhood Hits	1326	Shared Neighborhood Hits	19
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

TRIPB_HUMAN
NC score	0.001144 (rank : 144)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	149	Target Neighborhood Hits	1587	Shared Neighborhood Hits	29
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

DDX24_MOUSE
NC score	0.001089 (rank : 145)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	149	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

MYH14_HUMAN
NC score	0.000081 (rank : 146)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	149	Target Neighborhood Hits	995	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

ZN518_HUMAN
NC score	0.000073 (rank : 147)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	149	Target Neighborhood Hits	780	Shared Neighborhood Hits	9
SwissProt Accessions	Q6AHZ1, O15044, Q32MP4	Gene names	ZNF518, KIAA0335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 518.

CP135_HUMAN
NC score	0.000009 (rank : 148)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	149	Target Neighborhood Hits	1290	Shared Neighborhood Hits	18
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

EEA1_HUMAN
NC score	-0.001472 (rank : 149)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	149	Target Neighborhood Hits	1796	Shared Neighborhood Hits	25
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

NEK8_MOUSE
NC score	-0.003106 (rank : 150)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	149	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZR4, Q3U498, Q9D685	Gene names	Nek8, Jck
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8).

ZN583_HUMAN
NC score	-0.003417 (rank : 151)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	149	Target Neighborhood Hits	774	Shared Neighborhood Hits	7
SwissProt Accessions	Q96ND8, O14850, Q2NKK3	Gene names	ZNF583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583 (Zinc finger protein L3-5).

NEK8_HUMAN
NC score	-0.003436 (rank : 152)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	149	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	Q86SG6, Q2M1S6, Q8NDH1	Gene names	NEK8, JCK, NEK12A
Domain Architecture
Description	Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (NIMA-related kinase 12a).

ZN431_HUMAN
NC score	-0.004100 (rank : 153)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	149	Target Neighborhood Hits	765	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TF32, Q8IWC4	Gene names	ZNF431, KIAA1969
Domain Architecture
Description	Zinc finger protein 431.

ZN583_MOUSE
NC score	-0.004419 (rank : 154)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	149	Target Neighborhood Hits	774	Shared Neighborhood Hits	7
SwissProt Accessions	Q3V080, Q3V3L4	Gene names	Znf583, Zfp583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583.

ZNF85_HUMAN
NC score	-0.004544 (rank : 155)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	149	Target Neighborhood Hits	770	Shared Neighborhood Hits	7
SwissProt Accessions	Q03923	Gene names	ZNF85
Domain Architecture
Description	Zinc finger protein 85 (Zinc finger protein HPF4) (HTF1).

TITIN_HUMAN
NC score	-0.005827 (rank : 156)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	149	Target Neighborhood Hits	2923	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).