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Network neighborhood for query Sequence : UBP35_HUMAN

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UBP35_HUMAN
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP35_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	223	Target Neighborhood Hits	223	Shared Neighborhood Hits	223
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP38_MOUSE
θ value	1.78703e-165 (rank : 2)	NC score	0.942278 (rank : 3)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP38_HUMAN
θ value	1.28067e-163 (rank : 3)	NC score	0.942585 (rank : 2)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP48_HUMAN
θ value	4.74913e-17 (rank : 4)	NC score	0.734768 (rank : 8)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP50_MOUSE
θ value	1.80466e-16 (rank : 5)	NC score	0.741797 (rank : 7)
Query Neighborhood Hits	223	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP48_MOUSE
θ value	4.02038e-16 (rank : 6)	NC score	0.731804 (rank : 9)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP46_HUMAN
θ value	1.42992e-13 (rank : 7)	NC score	0.755024 (rank : 4)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	1.42992e-13 (rank : 8)	NC score	0.755024 (rank : 5)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP12_HUMAN
θ value	1.86753e-13 (rank : 9)	NC score	0.750168 (rank : 6)
Query Neighborhood Hits	223	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP21_HUMAN
θ value	1.2105e-12 (rank : 10)	NC score	0.710241 (rank : 15)
Query Neighborhood Hits	223	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP36_HUMAN
θ value	2.69671e-12 (rank : 11)	NC score	0.698545 (rank : 19)
Query Neighborhood Hits	223	Target Neighborhood Hits	232	Shared Neighborhood Hits	79
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP3_MOUSE
θ value	4.59992e-12 (rank : 12)	NC score	0.714732 (rank : 14)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBPW_MOUSE
θ value	6.00763e-12 (rank : 13)	NC score	0.719531 (rank : 12)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP42_HUMAN
θ value	7.84624e-12 (rank : 14)	NC score	0.675513 (rank : 32)
Query Neighborhood Hits	223	Target Neighborhood Hits	445	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP33_HUMAN
θ value	2.98157e-11 (rank : 15)	NC score	0.702393 (rank : 18)
Query Neighborhood Hits	223	Target Neighborhood Hits	157	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP34_HUMAN
θ value	2.98157e-11 (rank : 16)	NC score	0.624526 (rank : 44)
Query Neighborhood Hits	223	Target Neighborhood Hits	210	Shared Neighborhood Hits	81
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	2.98157e-11 (rank : 17)	NC score	0.625497 (rank : 43)
Query Neighborhood Hits	223	Target Neighborhood Hits	189	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP18_HUMAN
θ value	6.64225e-11 (rank : 18)	NC score	0.728118 (rank : 10)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP2_MOUSE
θ value	6.64225e-11 (rank : 19)	NC score	0.719962 (rank : 11)
Query Neighborhood Hits	223	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP47_MOUSE
θ value	1.133e-10 (rank : 20)	NC score	0.680293 (rank : 31)
Query Neighborhood Hits	223	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
θ value	1.9326e-10 (rank : 21)	NC score	0.681379 (rank : 30)
Query Neighborhood Hits	223	Target Neighborhood Hits	149	Shared Neighborhood Hits	76
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP2_HUMAN
θ value	3.29651e-10 (rank : 22)	NC score	0.716379 (rank : 13)
Query Neighborhood Hits	223	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP7_HUMAN
θ value	9.59137e-10 (rank : 23)	NC score	0.691157 (rank : 26)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	72
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP15_HUMAN
θ value	4.76016e-09 (rank : 24)	NC score	0.629986 (rank : 41)
Query Neighborhood Hits	223	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP21_MOUSE
θ value	4.76016e-09 (rank : 25)	NC score	0.702540 (rank : 17)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP15_MOUSE
θ value	6.21693e-09 (rank : 26)	NC score	0.630498 (rank : 40)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP16_HUMAN
θ value	1.06045e-08 (rank : 27)	NC score	0.696790 (rank : 20)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP22_HUMAN
θ value	1.06045e-08 (rank : 28)	NC score	0.695924 (rank : 21)
Query Neighborhood Hits	223	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
θ value	1.06045e-08 (rank : 29)	NC score	0.695440 (rank : 22)
Query Neighborhood Hits	223	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
θ value	1.80886e-08 (rank : 30)	NC score	0.689401 (rank : 27)
Query Neighborhood Hits	223	Target Neighborhood Hits	162	Shared Neighborhood Hits	78
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP8_HUMAN
θ value	2.36244e-08 (rank : 31)	NC score	0.666205 (rank : 34)
Query Neighborhood Hits	223	Target Neighborhood Hits	751	Shared Neighborhood Hits	148
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP8_MOUSE
θ value	2.36244e-08 (rank : 32)	NC score	0.691355 (rank : 25)
Query Neighborhood Hits	223	Target Neighborhood Hits	362	Shared Neighborhood Hits	108
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP24_HUMAN
θ value	3.08544e-08 (rank : 33)	NC score	0.648451 (rank : 38)
Query Neighborhood Hits	223	Target Neighborhood Hits	96	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP50_HUMAN
θ value	3.08544e-08 (rank : 34)	NC score	0.703738 (rank : 16)
Query Neighborhood Hits	223	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP40_HUMAN
θ value	4.0297e-08 (rank : 35)	NC score	0.668724 (rank : 33)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP44_HUMAN
θ value	4.0297e-08 (rank : 36)	NC score	0.659466 (rank : 36)
Query Neighborhood Hits	223	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP4_HUMAN
θ value	5.26297e-08 (rank : 37)	NC score	0.626623 (rank : 42)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP20_HUMAN
θ value	6.87365e-08 (rank : 38)	NC score	0.693866 (rank : 23)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP25_HUMAN
θ value	6.87365e-08 (rank : 39)	NC score	0.490010 (rank : 64)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP28_MOUSE
θ value	6.87365e-08 (rank : 40)	NC score	0.509158 (rank : 62)
Query Neighborhood Hits	223	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
θ value	8.97725e-08 (rank : 41)	NC score	0.509737 (rank : 61)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP49_MOUSE
θ value	1.99992e-07 (rank : 42)	NC score	0.662060 (rank : 35)
Query Neighborhood Hits	223	Target Neighborhood Hits	91	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP4_MOUSE
θ value	1.99992e-07 (rank : 43)	NC score	0.620987 (rank : 45)
Query Neighborhood Hits	223	Target Neighborhood Hits	90	Shared Neighborhood Hits	71
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP25_MOUSE
θ value	3.41135e-07 (rank : 44)	NC score	0.491506 (rank : 63)
Query Neighborhood Hits	223	Target Neighborhood Hits	116	Shared Neighborhood Hits	74
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UB17L_HUMAN
θ value	4.45536e-07 (rank : 45)	NC score	0.687640 (rank : 28)
Query Neighborhood Hits	223	Target Neighborhood Hits	83	Shared Neighborhood Hits	70
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP18_MOUSE
θ value	4.45536e-07 (rank : 46)	NC score	0.693291 (rank : 24)
Query Neighborhood Hits	223	Target Neighborhood Hits	77	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP32_HUMAN
θ value	7.59969e-07 (rank : 47)	NC score	0.558879 (rank : 56)
Query Neighborhood Hits	223	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP6_HUMAN
θ value	9.92553e-07 (rank : 48)	NC score	0.527848 (rank : 58)
Query Neighborhood Hits	223	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP43_HUMAN
θ value	2.88788e-06 (rank : 49)	NC score	0.619385 (rank : 47)
Query Neighborhood Hits	223	Target Neighborhood Hits	144	Shared Neighborhood Hits	72
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP31_HUMAN
θ value	3.77169e-06 (rank : 50)	NC score	0.613046 (rank : 49)
Query Neighborhood Hits	223	Target Neighborhood Hits	293	Shared Neighborhood Hits	80
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP49_HUMAN
θ value	6.43352e-06 (rank : 51)	NC score	0.651094 (rank : 37)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP1_HUMAN
θ value	8.40245e-06 (rank : 52)	NC score	0.630847 (rank : 39)
Query Neighborhood Hits	223	Target Neighborhood Hits	259	Shared Neighborhood Hits	84
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP3_HUMAN
θ value	1.43324e-05 (rank : 53)	NC score	0.684352 (rank : 29)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP43_MOUSE
θ value	1.43324e-05 (rank : 54)	NC score	0.619730 (rank : 46)
Query Neighborhood Hits	223	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP37_HUMAN
θ value	1.87187e-05 (rank : 55)	NC score	0.552485 (rank : 57)
Query Neighborhood Hits	223	Target Neighborhood Hits	208	Shared Neighborhood Hits	85
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP11_HUMAN
θ value	3.19293e-05 (rank : 56)	NC score	0.619266 (rank : 48)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

USP9X_HUMAN
θ value	0.000270298 (rank : 57)	NC score	0.560219 (rank : 54)
Query Neighborhood Hits	223	Target Neighborhood Hits	161	Shared Neighborhood Hits	75
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9Y_HUMAN
θ value	0.000270298 (rank : 58)	NC score	0.566184 (rank : 52)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	72
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

USP9X_MOUSE
θ value	0.000602161 (rank : 59)	NC score	0.559494 (rank : 55)
Query Neighborhood Hits	223	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP13_HUMAN
θ value	0.00134147 (rank : 60)	NC score	0.447290 (rank : 67)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	70
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP14_MOUSE
θ value	0.00134147 (rank : 61)	NC score	0.565156 (rank : 53)
Query Neighborhood Hits	223	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_HUMAN
θ value	0.00298849 (rank : 62)	NC score	0.575043 (rank : 51)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP26_HUMAN
θ value	0.00390308 (rank : 63)	NC score	0.451081 (rank : 66)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP10_HUMAN
θ value	0.00665767 (rank : 64)	NC score	0.522046 (rank : 60)
Query Neighborhood Hits	223	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

CGRE1_MOUSE
θ value	0.00869519 (rank : 65)	NC score	0.065127 (rank : 88)
Query Neighborhood Hits	223	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

UBP30_HUMAN
θ value	0.0113563 (rank : 66)	NC score	0.579595 (rank : 50)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP10_MOUSE
θ value	0.0148317 (rank : 67)	NC score	0.524328 (rank : 59)
Query Neighborhood Hits	223	Target Neighborhood Hits	150	Shared Neighborhood Hits	70
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP53_MOUSE
θ value	0.0148317 (rank : 68)	NC score	0.122501 (rank : 75)
Query Neighborhood Hits	223	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP5_HUMAN
θ value	0.0148317 (rank : 69)	NC score	0.433523 (rank : 69)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

ASPX_HUMAN
θ value	0.0193708 (rank : 70)	NC score	0.061397 (rank : 95)
Query Neighborhood Hits	223	Target Neighborhood Hits	148	Shared Neighborhood Hits	13
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

TCAL5_HUMAN
θ value	0.0193708 (rank : 71)	NC score	0.052750 (rank : 107)
Query Neighborhood Hits	223	Target Neighborhood Hits	806	Shared Neighborhood Hits	51
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

UBP29_HUMAN
θ value	0.0193708 (rank : 72)	NC score	0.473295 (rank : 65)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP53_HUMAN
θ value	0.0193708 (rank : 73)	NC score	0.125463 (rank : 74)
Query Neighborhood Hits	223	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

NSBP1_MOUSE
θ value	0.0252991 (rank : 74)	NC score	0.073352 (rank : 82)
Query Neighborhood Hits	223	Target Neighborhood Hits	681	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

MDC1_MOUSE
θ value	0.0330416 (rank : 75)	NC score	0.052441 (rank : 109)
Query Neighborhood Hits	223	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SEC63_HUMAN
θ value	0.0330416 (rank : 76)	NC score	0.064686 (rank : 89)
Query Neighborhood Hits	223	Target Neighborhood Hits	586	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

UBP5_MOUSE
θ value	0.0330416 (rank : 77)	NC score	0.430753 (rank : 70)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

SEC63_MOUSE
θ value	0.0431538 (rank : 78)	NC score	0.061475 (rank : 94)
Query Neighborhood Hits	223	Target Neighborhood Hits	601	Shared Neighborhood Hits	55
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

NF2L3_HUMAN
θ value	0.0563607 (rank : 79)	NC score	0.045165 (rank : 125)
Query Neighborhood Hits	223	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

OXRP_HUMAN
θ value	0.0563607 (rank : 80)	NC score	0.030603 (rank : 150)
Query Neighborhood Hits	223	Target Neighborhood Hits	544	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ALO17_HUMAN
θ value	0.0961366 (rank : 81)	NC score	0.063942 (rank : 90)
Query Neighborhood Hits	223	Target Neighborhood Hits	317	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

IWS1_MOUSE
θ value	0.0961366 (rank : 82)	NC score	0.061834 (rank : 93)
Query Neighborhood Hits	223	Target Neighborhood Hits	1258	Shared Neighborhood Hits	73
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MDC1_HUMAN
θ value	0.0961366 (rank : 83)	NC score	0.048391 (rank : 118)
Query Neighborhood Hits	223	Target Neighborhood Hits	1446	Shared Neighborhood Hits	66
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MINT_MOUSE
θ value	0.125558 (rank : 84)	NC score	0.040634 (rank : 130)
Query Neighborhood Hits	223	Target Neighborhood Hits	1514	Shared Neighborhood Hits	66
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TCRG1_HUMAN
θ value	0.125558 (rank : 85)	NC score	0.060080 (rank : 97)
Query Neighborhood Hits	223	Target Neighborhood Hits	929	Shared Neighborhood Hits	71
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	0.125558 (rank : 86)	NC score	0.059674 (rank : 98)
Query Neighborhood Hits	223	Target Neighborhood Hits	947	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

ZKSC1_HUMAN
θ value	0.125558 (rank : 87)	NC score	-0.001352 (rank : 237)
Query Neighborhood Hits	223	Target Neighborhood Hits	949	Shared Neighborhood Hits	19
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

IWS1_HUMAN
θ value	0.163984 (rank : 88)	NC score	0.060839 (rank : 96)
Query Neighborhood Hits	223	Target Neighborhood Hits	1241	Shared Neighborhood Hits	76
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BSCL2_HUMAN
θ value	0.21417 (rank : 89)	NC score	0.062495 (rank : 91)
Query Neighborhood Hits	223	Target Neighborhood Hits	148	Shared Neighborhood Hits	18
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

PRG3_MOUSE
θ value	0.21417 (rank : 90)	NC score	0.030071 (rank : 156)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

DUS1L_HUMAN
θ value	0.279714 (rank : 91)	NC score	0.030182 (rank : 155)
Query Neighborhood Hits	223	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1R4, Q96AI3	Gene names	DUS1L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

PSMD2_MOUSE
θ value	0.279714 (rank : 92)	NC score	0.046192 (rank : 122)
Query Neighborhood Hits	223	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

UBP29_MOUSE
θ value	0.279714 (rank : 93)	NC score	0.446412 (rank : 68)
Query Neighborhood Hits	223	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

MLL2_HUMAN
θ value	0.365318 (rank : 94)	NC score	0.028170 (rank : 163)
Query Neighborhood Hits	223	Target Neighborhood Hits	1788	Shared Neighborhood Hits	73
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OSBL8_HUMAN
θ value	0.365318 (rank : 95)	NC score	0.027086 (rank : 179)
Query Neighborhood Hits	223	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

SRPK1_MOUSE
θ value	0.365318 (rank : 96)	NC score	0.013287 (rank : 209)
Query Neighborhood Hits	223	Target Neighborhood Hits	639	Shared Neighborhood Hits	16
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

ZNF96_MOUSE
θ value	0.365318 (rank : 97)	NC score	-0.002991 (rank : 238)
Query Neighborhood Hits	223	Target Neighborhood Hits	749	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1D7	Gene names	Znf96, Zfp96
Domain Architecture
Description	Zinc finger protein 96 (Zfp-96).

BSCL2_MOUSE
θ value	0.47712 (rank : 98)	NC score	0.054746 (rank : 103)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

MYST3_MOUSE
θ value	0.47712 (rank : 99)	NC score	0.042097 (rank : 128)
Query Neighborhood Hits	223	Target Neighborhood Hits	688	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

SPRL1_MOUSE
θ value	0.47712 (rank : 100)	NC score	0.047922 (rank : 119)
Query Neighborhood Hits	223	Target Neighborhood Hits	403	Shared Neighborhood Hits	49
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TCAL3_HUMAN
θ value	0.47712 (rank : 101)	NC score	0.047188 (rank : 120)
Query Neighborhood Hits	223	Target Neighborhood Hits	274	Shared Neighborhood Hits	24
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

AKA12_HUMAN
θ value	0.62314 (rank : 102)	NC score	0.062449 (rank : 92)
Query Neighborhood Hits	223	Target Neighborhood Hits	825	Shared Neighborhood Hits	79
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AR13B_HUMAN
θ value	0.62314 (rank : 103)	NC score	0.019863 (rank : 199)
Query Neighborhood Hits	223	Target Neighborhood Hits	528	Shared Neighborhood Hits	35
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

MYO5A_HUMAN
θ value	0.62314 (rank : 104)	NC score	0.028705 (rank : 159)
Query Neighborhood Hits	223	Target Neighborhood Hits	1092	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

PININ_HUMAN
θ value	0.62314 (rank : 105)	NC score	0.073657 (rank : 81)
Query Neighborhood Hits	223	Target Neighborhood Hits	753	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.072350 (rank : 83)
Query Neighborhood Hits	223	Target Neighborhood Hits	777	Shared Neighborhood Hits	93
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

BPAEA_HUMAN
θ value	0.813845 (rank : 107)	NC score	0.027343 (rank : 177)
Query Neighborhood Hits	223	Target Neighborhood Hits	1369	Shared Neighborhood Hits	82
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ERIC1_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.045425 (rank : 124)
Query Neighborhood Hits	223	Target Neighborhood Hits	364	Shared Neighborhood Hits	32
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

IF3A_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.053367 (rank : 105)
Query Neighborhood Hits	223	Target Neighborhood Hits	875	Shared Neighborhood Hits	84
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	0.813845 (rank : 110)	NC score	0.053933 (rank : 104)
Query Neighborhood Hits	223	Target Neighborhood Hits	871	Shared Neighborhood Hits	86
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

KMHN1_MOUSE
θ value	0.813845 (rank : 111)	NC score	0.033807 (rank : 136)
Query Neighborhood Hits	223	Target Neighborhood Hits	949	Shared Neighborhood Hits	66
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

FA21C_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.050731 (rank : 116)
Query Neighborhood Hits	223	Target Neighborhood Hits	194	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

PALB2_HUMAN
θ value	1.06291 (rank : 113)	NC score	0.030483 (rank : 152)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

STK10_MOUSE
θ value	1.06291 (rank : 114)	NC score	0.008962 (rank : 221)
Query Neighborhood Hits	223	Target Neighborhood Hits	2132	Shared Neighborhood Hits	90
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MYO5A_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.027897 (rank : 168)
Query Neighborhood Hits	223	Target Neighborhood Hits	1117	Shared Neighborhood Hits	73
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

NASP_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.052536 (rank : 108)
Query Neighborhood Hits	223	Target Neighborhood Hits	709	Shared Neighborhood Hits	72
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PSMD2_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.039678 (rank : 132)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	Q13200, Q12932, Q15321, Q96I12	Gene names	PSMD2, TRAP2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).

SMC1A_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.036084 (rank : 134)
Query Neighborhood Hits	223	Target Neighborhood Hits	1346	Shared Neighborhood Hits	84
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	1.38821 (rank : 119)	NC score	0.036063 (rank : 135)
Query Neighborhood Hits	223	Target Neighborhood Hits	1384	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

ACINU_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.055474 (rank : 102)
Query Neighborhood Hits	223	Target Neighborhood Hits	828	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ADDB_MOUSE
θ value	1.81305 (rank : 121)	NC score	0.023446 (rank : 190)
Query Neighborhood Hits	223	Target Neighborhood Hits	574	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BPA1_MOUSE
θ value	1.81305 (rank : 122)	NC score	0.025032 (rank : 186)
Query Neighborhood Hits	223	Target Neighborhood Hits	1477	Shared Neighborhood Hits	87
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD11_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.039947 (rank : 131)
Query Neighborhood Hits	223	Target Neighborhood Hits	822	Shared Neighborhood Hits	69
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CF010_HUMAN
θ value	1.81305 (rank : 124)	NC score	0.046970 (rank : 121)
Query Neighborhood Hits	223	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

KNTC2_HUMAN
θ value	1.81305 (rank : 125)	NC score	0.030514 (rank : 151)
Query Neighborhood Hits	223	Target Neighborhood Hits	673	Shared Neighborhood Hits	54
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

NF2L3_MOUSE
θ value	1.81305 (rank : 126)	NC score	0.033706 (rank : 138)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

UBP26_MOUSE
θ value	1.81305 (rank : 127)	NC score	0.359436 (rank : 73)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	71
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

BRD8_HUMAN
θ value	2.36792 (rank : 128)	NC score	0.027283 (rank : 178)
Query Neighborhood Hits	223	Target Neighborhood Hits	292	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	2.36792 (rank : 129)	NC score	0.032289 (rank : 143)
Query Neighborhood Hits	223	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

MDN1_HUMAN
θ value	2.36792 (rank : 130)	NC score	0.057548 (rank : 100)
Query Neighborhood Hits	223	Target Neighborhood Hits	662	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MYH11_HUMAN
θ value	2.36792 (rank : 131)	NC score	0.028260 (rank : 162)
Query Neighborhood Hits	223	Target Neighborhood Hits	1806	Shared Neighborhood Hits	90
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	2.36792 (rank : 132)	NC score	0.027981 (rank : 164)
Query Neighborhood Hits	223	Target Neighborhood Hits	1777	Shared Neighborhood Hits	88
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

TAXB1_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.031563 (rank : 146)
Query Neighborhood Hits	223	Target Neighborhood Hits	829	Shared Neighborhood Hits	62
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TP53B_MOUSE
θ value	2.36792 (rank : 134)	NC score	0.033802 (rank : 137)
Query Neighborhood Hits	223	Target Neighborhood Hits	644	Shared Neighborhood Hits	40
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

UBP54_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.100142 (rank : 77)
Query Neighborhood Hits	223	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_MOUSE
θ value	2.36792 (rank : 136)	NC score	0.100672 (rank : 76)
Query Neighborhood Hits	223	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

CCD46_MOUSE
θ value	3.0926 (rank : 137)	NC score	0.031841 (rank : 145)
Query Neighborhood Hits	223	Target Neighborhood Hits	1405	Shared Neighborhood Hits	84
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CENPF_HUMAN
θ value	3.0926 (rank : 138)	NC score	0.027506 (rank : 173)
Query Neighborhood Hits	223	Target Neighborhood Hits	1932	Shared Neighborhood Hits	84
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GASP1_HUMAN
θ value	3.0926 (rank : 139)	NC score	0.011851 (rank : 211)
Query Neighborhood Hits	223	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JY77, O43168, Q96LA1	Gene names	GPRASP1, GASP, KIAA0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

HASP_MOUSE
θ value	3.0926 (rank : 140)	NC score	0.017689 (rank : 203)
Query Neighborhood Hits	223	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

LEO1_MOUSE
θ value	3.0926 (rank : 141)	NC score	0.050837 (rank : 115)
Query Neighborhood Hits	223	Target Neighborhood Hits	946	Shared Neighborhood Hits	71
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NSD1_MOUSE
θ value	3.0926 (rank : 142)	NC score	0.013442 (rank : 208)
Query Neighborhood Hits	223	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SAFB2_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.032640 (rank : 141)
Query Neighborhood Hits	223	Target Neighborhood Hits	720	Shared Neighborhood Hits	78
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

STIM1_MOUSE
θ value	3.0926 (rank : 144)	NC score	0.026365 (rank : 181)
Query Neighborhood Hits	223	Target Neighborhood Hits	660	Shared Neighborhood Hits	48
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TAXB1_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.032842 (rank : 140)
Query Neighborhood Hits	223	Target Neighborhood Hits	886	Shared Neighborhood Hits	62
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TEX14_MOUSE
θ value	3.0926 (rank : 146)	NC score	0.004524 (rank : 234)
Query Neighborhood Hits	223	Target Neighborhood Hits	1333	Shared Neighborhood Hits	53
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TS101_MOUSE
θ value	3.0926 (rank : 147)	NC score	0.024997 (rank : 187)
Query Neighborhood Hits	223	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

UACA_MOUSE
θ value	3.0926 (rank : 148)	NC score	0.022516 (rank : 192)
Query Neighborhood Hits	223	Target Neighborhood Hits	1620	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

CLGN_MOUSE
θ value	4.03905 (rank : 149)	NC score	0.010195 (rank : 216)
Query Neighborhood Hits	223	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

CTGE5_MOUSE
θ value	4.03905 (rank : 150)	NC score	0.027440 (rank : 174)
Query Neighborhood Hits	223	Target Neighborhood Hits	928	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

GOGA5_HUMAN
θ value	4.03905 (rank : 151)	NC score	0.027925 (rank : 166)
Query Neighborhood Hits	223	Target Neighborhood Hits	1168	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	4.03905 (rank : 152)	NC score	0.029187 (rank : 158)
Query Neighborhood Hits	223	Target Neighborhood Hits	1434	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

LAT1_MOUSE
θ value	4.03905 (rank : 153)	NC score	0.006928 (rank : 225)
Query Neighborhood Hits	223	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z127, Q9JMI4	Gene names	Slc7a5, Lat1
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC).

LSP1_HUMAN
θ value	4.03905 (rank : 154)	NC score	0.027545 (rank : 172)
Query Neighborhood Hits	223	Target Neighborhood Hits	142	Shared Neighborhood Hits	19
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

NEST_HUMAN
θ value	4.03905 (rank : 155)	NC score	0.031993 (rank : 144)
Query Neighborhood Hits	223	Target Neighborhood Hits	1305	Shared Neighborhood Hits	96
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

OPTN_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.032451 (rank : 142)
Query Neighborhood Hits	223	Target Neighborhood Hits	827	Shared Neighborhood Hits	70
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	4.03905 (rank : 157)	NC score	0.030360 (rank : 154)
Query Neighborhood Hits	223	Target Neighborhood Hits	1120	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

POTE8_HUMAN
θ value	4.03905 (rank : 158)	NC score	0.004569 (rank : 233)
Query Neighborhood Hits	223	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

PP16A_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.002750 (rank : 236)
Query Neighborhood Hits	223	Target Neighborhood Hits	340	Shared Neighborhood Hits	8
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

RABE1_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.030723 (rank : 148)
Query Neighborhood Hits	223	Target Neighborhood Hits	1104	Shared Neighborhood Hits	74
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.030426 (rank : 153)
Query Neighborhood Hits	223	Target Neighborhood Hits	1105	Shared Neighborhood Hits	74
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RUFY1_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.025957 (rank : 182)
Query Neighborhood Hits	223	Target Neighborhood Hits	765	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.024592 (rank : 188)
Query Neighborhood Hits	223	Target Neighborhood Hits	1208	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SRPK1_HUMAN
θ value	4.03905 (rank : 164)	NC score	0.011572 (rank : 214)
Query Neighborhood Hits	223	Target Neighborhood Hits	706	Shared Neighborhood Hits	27
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

STIM1_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.025448 (rank : 185)
Query Neighborhood Hits	223	Target Neighborhood Hits	665	Shared Neighborhood Hits	47
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

AL3A1_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.008037 (rank : 223)
Query Neighborhood Hits	223	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P30838, Q9BT37	Gene names	ALDH3A1, ALDH3
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (ALDHIII).

AL3A1_MOUSE
θ value	5.27518 (rank : 167)	NC score	0.008670 (rank : 222)
Query Neighborhood Hits	223	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	P47739, Q9R203	Gene names	Aldh3a1, Ahd-4, Ahd4, Aldh3, Aldh4
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (Dioxin-inducible aldehyde dehydrogenase 3).

CCD21_HUMAN
θ value	5.27518 (rank : 168)	NC score	0.033326 (rank : 139)
Query Neighborhood Hits	223	Target Neighborhood Hits	1228	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CP250_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.028536 (rank : 161)
Query Neighborhood Hits	223	Target Neighborhood Hits	1805	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CROCC_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.026878 (rank : 180)
Query Neighborhood Hits	223	Target Neighborhood Hits	1409	Shared Neighborhood Hits	75
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA4_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.030617 (rank : 149)
Query Neighborhood Hits	223	Target Neighborhood Hits	2034	Shared Neighborhood Hits	96
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

LEO1_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.052436 (rank : 110)
Query Neighborhood Hits	223	Target Neighborhood Hits	958	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LIPB1_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.021778 (rank : 195)
Query Neighborhood Hits	223	Target Neighborhood Hits	640	Shared Neighborhood Hits	50
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

MINT_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.042962 (rank : 127)
Query Neighborhood Hits	223	Target Neighborhood Hits	1291	Shared Neighborhood Hits	80
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYH10_HUMAN
θ value	5.27518 (rank : 175)	NC score	0.027791 (rank : 169)
Query Neighborhood Hits	223	Target Neighborhood Hits	1620	Shared Neighborhood Hits	84
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NPBL_MOUSE
θ value	5.27518 (rank : 176)	NC score	0.041574 (rank : 129)
Query Neighborhood Hits	223	Target Neighborhood Hits	1041	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PEG3_MOUSE
θ value	5.27518 (rank : 177)	NC score	0.005254 (rank : 229)
Query Neighborhood Hits	223	Target Neighborhood Hits	1101	Shared Neighborhood Hits	46
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PHLB1_HUMAN
θ value	5.27518 (rank : 178)	NC score	0.022578 (rank : 191)
Query Neighborhood Hits	223	Target Neighborhood Hits	1038	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRAM7_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.009084 (rank : 219)
Query Neighborhood Hits	223	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VXH5	Gene names	PRAMEF7
Domain Architecture	No domain graphic available
Description	PRAME family member 7.

PRAM8_HUMAN
θ value	5.27518 (rank : 180)	NC score	0.009079 (rank : 220)
Query Neighborhood Hits	223	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VWM4	Gene names	PRAMEF8
Domain Architecture	No domain graphic available
Description	PRAME family member 8.

PSA5_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.011630 (rank : 212)
Query Neighborhood Hits	223	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P28066, Q6IBF7	Gene names	PSMA5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).

PSA5_MOUSE
θ value	5.27518 (rank : 182)	NC score	0.011630 (rank : 213)
Query Neighborhood Hits	223	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2U1	Gene names	Psma5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).

RIMB1_MOUSE
θ value	5.27518 (rank : 183)	NC score	0.025697 (rank : 184)
Query Neighborhood Hits	223	Target Neighborhood Hits	1376	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TRI17_MOUSE
θ value	5.27518 (rank : 184)	NC score	0.004831 (rank : 232)
Query Neighborhood Hits	223	Target Neighborhood Hits	620	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

CNTRB_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.027401 (rank : 176)
Query Neighborhood Hits	223	Target Neighborhood Hits	1029	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

KI13B_HUMAN
θ value	6.88961 (rank : 186)	NC score	0.005324 (rank : 228)
Query Neighborhood Hits	223	Target Neighborhood Hits	492	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

MRCKA_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.005122 (rank : 230)
Query Neighborhood Hits	223	Target Neighborhood Hits	1999	Shared Neighborhood Hits	74
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MYH13_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.024391 (rank : 189)
Query Neighborhood Hits	223	Target Neighborhood Hits	1504	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH9_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.027969 (rank : 165)
Query Neighborhood Hits	223	Target Neighborhood Hits	1762	Shared Neighborhood Hits	89
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	6.88961 (rank : 190)	NC score	0.028702 (rank : 160)
Query Neighborhood Hits	223	Target Neighborhood Hits	1829	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PHF20_MOUSE
θ value	6.88961 (rank : 191)	NC score	0.020213 (rank : 198)
Query Neighborhood Hits	223	Target Neighborhood Hits	513	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

RB6I2_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.027628 (rank : 171)
Query Neighborhood Hits	223	Target Neighborhood Hits	1584	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	6.88961 (rank : 193)	NC score	0.027898 (rank : 167)
Query Neighborhood Hits	223	Target Neighborhood Hits	1433	Shared Neighborhood Hits	80
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SMRC1_MOUSE
θ value	6.88961 (rank : 194)	NC score	0.027417 (rank : 175)
Query Neighborhood Hits	223	Target Neighborhood Hits	459	Shared Neighborhood Hits	56
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

TCAL4_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.037733 (rank : 133)
Query Neighborhood Hits	223	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q96EI5, Q8WY12, Q9H2H1, Q9H775	Gene names	TCEAL4
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 4 (TCEA-like protein 4) (Transcription elongation factor S-II protein-like 4).

TTC1_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.009485 (rank : 218)
Query Neighborhood Hits	223	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TTF2_MOUSE
θ value	6.88961 (rank : 197)	NC score	0.010275 (rank : 215)
Query Neighborhood Hits	223	Target Neighborhood Hits	364	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ALDOB_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.005709 (rank : 227)
Query Neighborhood Hits	223	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P05062, Q13741, Q13742	Gene names	ALDOB, ALDB
Domain Architecture
Description	Fructose-bisphosphate aldolase B (EC 4.1.2.13) (Liver-type aldolase).

ANR26_MOUSE
θ value	8.99809 (rank : 199)	NC score	0.021140 (rank : 197)
Query Neighborhood Hits	223	Target Neighborhood Hits	1554	Shared Neighborhood Hits	78
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CDKL5_HUMAN
θ value	8.99809 (rank : 200)	NC score	-0.004368 (rank : 240)
Query Neighborhood Hits	223	Target Neighborhood Hits	967	Shared Neighborhood Hits	16
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CJ095_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.017963 (rank : 202)
Query Neighborhood Hits	223	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

DMN_HUMAN
θ value	8.99809 (rank : 202)	NC score	0.018805 (rank : 201)
Query Neighborhood Hits	223	Target Neighborhood Hits	690	Shared Neighborhood Hits	64
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

ETV3_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.006405 (rank : 226)
Query Neighborhood Hits	223	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

FLIP1_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.025762 (rank : 183)
Query Neighborhood Hits	223	Target Neighborhood Hits	1405	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GANAB_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.005086 (rank : 231)
Query Neighborhood Hits	223	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

GOGA4_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.029747 (rank : 157)
Query Neighborhood Hits	223	Target Neighborhood Hits	1939	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

INVO_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.031512 (rank : 147)
Query Neighborhood Hits	223	Target Neighborhood Hits	474	Shared Neighborhood Hits	54
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

JIP3_MOUSE
θ value	8.99809 (rank : 208)	NC score	0.016980 (rank : 206)
Query Neighborhood Hits	223	Target Neighborhood Hits	759	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

LIMA1_HUMAN
θ value	8.99809 (rank : 209)	NC score	0.008005 (rank : 224)
Query Neighborhood Hits	223	Target Neighborhood Hits	309	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

LSP1_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.019200 (rank : 200)
Query Neighborhood Hits	223	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

MAP1B_MOUSE
θ value	8.99809 (rank : 211)	NC score	0.045455 (rank : 123)
Query Neighborhood Hits	223	Target Neighborhood Hits	977	Shared Neighborhood Hits	93
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MATR3_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.017398 (rank : 204)
Query Neighborhood Hits	223	Target Neighborhood Hits	325	Shared Neighborhood Hits	34
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MYRIP_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.014269 (rank : 207)
Query Neighborhood Hits	223	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NKTR_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.017021 (rank : 205)
Query Neighborhood Hits	223	Target Neighborhood Hits	658	Shared Neighborhood Hits	48
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PHF3_HUMAN
θ value	8.99809 (rank : 215)	NC score	0.022306 (rank : 194)
Query Neighborhood Hits	223	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RRP5_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.027697 (rank : 170)
Query Neighborhood Hits	223	Target Neighborhood Hits	291	Shared Neighborhood Hits	40
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

RSF1_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.044348 (rank : 126)
Query Neighborhood Hits	223	Target Neighborhood Hits	539	Shared Neighborhood Hits	70
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SETB1_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.012674 (rank : 210)
Query Neighborhood Hits	223	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

TAOK1_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.003735 (rank : 235)
Query Neighborhood Hits	223	Target Neighborhood Hits	1734	Shared Neighborhood Hits	72
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

TCAL7_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.021209 (rank : 196)
Query Neighborhood Hits	223	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRU2, Q96AT4	Gene names	TCEAL7
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 7 (TCEA-like protein 7) (Transcription elongation factor S-II protein-like 7).

TRAK1_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.022446 (rank : 193)
Query Neighborhood Hits	223	Target Neighborhood Hits	660	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

WNK1_MOUSE
θ value	8.99809 (rank : 222)	NC score	-0.003620 (rank : 239)
Query Neighborhood Hits	223	Target Neighborhood Hits	1179	Shared Neighborhood Hits	21
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ZCH11_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.010084 (rank : 217)
Query Neighborhood Hits	223	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

BRAP_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.085454 (rank : 79)
Query Neighborhood Hits	223	Target Neighborhood Hits	560	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.091762 (rank : 78)
Query Neighborhood Hits	223	Target Neighborhood Hits	409	Shared Neighborhood Hits	56
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

DMP1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.052011 (rank : 111)
Query Neighborhood Hits	223	Target Neighborhood Hits	491	Shared Neighborhood Hits	60
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DMP1_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.053226 (rank : 106)
Query Neighborhood Hits	223	Target Neighborhood Hits	498	Shared Neighborhood Hits	66
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

GGNB1_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.050463 (rank : 117)
Query Neighborhood Hits	223	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GGNB1_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.067472 (rank : 86)
Query Neighborhood Hits	223	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

HDAC6_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.051319 (rank : 114)
Query Neighborhood Hits	223	Target Neighborhood Hits	145	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HDAC6_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.051526 (rank : 113)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

IF2P_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.051960 (rank : 112)
Query Neighborhood Hits	223	Target Neighborhood Hits	889	Shared Neighborhood Hits	111
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NSBP1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.073672 (rank : 80)
Query Neighborhood Hits	223	Target Neighborhood Hits	251	Shared Neighborhood Hits	56
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PTMA_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.066266 (rank : 87)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.068259 (rank : 85)
Query Neighborhood Hits	223	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.069090 (rank : 84)
Query Neighborhood Hits	223	Target Neighborhood Hits	111	Shared Neighborhood Hits	37
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.057269 (rank : 101)
Query Neighborhood Hits	223	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

RPGR1_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.058700 (rank : 99)
Query Neighborhood Hits	223	Target Neighborhood Hits	713	Shared Neighborhood Hits	115
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SNUT2_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.394874 (rank : 72)
Query Neighborhood Hits	223	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.403574 (rank : 71)
Query Neighborhood Hits	223	Target Neighborhood Hits	80	Shared Neighborhood Hits	59
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

Hits sorted by NC score

UBP35_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	223	Target Neighborhood Hits	223	Shared Neighborhood Hits	223
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP38_HUMAN
NC score	0.942585 (rank : 2)	θ value	1.28067e-163 (rank : 3)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
NC score	0.942278 (rank : 3)	θ value	1.78703e-165 (rank : 2)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP46_HUMAN
NC score	0.755024 (rank : 4)	θ value	1.42992e-13 (rank : 7)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.755024 (rank : 5)	θ value	1.42992e-13 (rank : 8)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP12_HUMAN
NC score	0.750168 (rank : 6)	θ value	1.86753e-13 (rank : 9)
Query Neighborhood Hits	223	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP50_MOUSE
NC score	0.741797 (rank : 7)	θ value	1.80466e-16 (rank : 5)
Query Neighborhood Hits	223	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP48_HUMAN
NC score	0.734768 (rank : 8)	θ value	4.74913e-17 (rank : 4)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.731804 (rank : 9)	θ value	4.02038e-16 (rank : 6)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP18_HUMAN
NC score	0.728118 (rank : 10)	θ value	6.64225e-11 (rank : 18)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP2_MOUSE
NC score	0.719962 (rank : 11)	θ value	6.64225e-11 (rank : 19)
Query Neighborhood Hits	223	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBPW_MOUSE
NC score	0.719531 (rank : 12)	θ value	6.00763e-12 (rank : 13)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP2_HUMAN
NC score	0.716379 (rank : 13)	θ value	3.29651e-10 (rank : 22)
Query Neighborhood Hits	223	Target Neighborhood Hits	84	Shared Neighborhood Hits	71
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP3_MOUSE
NC score	0.714732 (rank : 14)	θ value	4.59992e-12 (rank : 12)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP21_HUMAN
NC score	0.710241 (rank : 15)	θ value	1.2105e-12 (rank : 10)
Query Neighborhood Hits	223	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP50_HUMAN
NC score	0.703738 (rank : 16)	θ value	3.08544e-08 (rank : 34)
Query Neighborhood Hits	223	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP21_MOUSE
NC score	0.702540 (rank : 17)	θ value	4.76016e-09 (rank : 25)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP33_HUMAN
NC score	0.702393 (rank : 18)	θ value	2.98157e-11 (rank : 15)
Query Neighborhood Hits	223	Target Neighborhood Hits	157	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP36_HUMAN
NC score	0.698545 (rank : 19)	θ value	2.69671e-12 (rank : 11)
Query Neighborhood Hits	223	Target Neighborhood Hits	232	Shared Neighborhood Hits	79
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP16_HUMAN
NC score	0.696790 (rank : 20)	θ value	1.06045e-08 (rank : 27)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP22_HUMAN
NC score	0.695924 (rank : 21)	θ value	1.06045e-08 (rank : 28)
Query Neighborhood Hits	223	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
NC score	0.695440 (rank : 22)	θ value	1.06045e-08 (rank : 29)
Query Neighborhood Hits	223	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP20_HUMAN
NC score	0.693866 (rank : 23)	θ value	6.87365e-08 (rank : 38)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP18_MOUSE
NC score	0.693291 (rank : 24)	θ value	4.45536e-07 (rank : 46)
Query Neighborhood Hits	223	Target Neighborhood Hits	77	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP8_MOUSE
NC score	0.691355 (rank : 25)	θ value	2.36244e-08 (rank : 32)
Query Neighborhood Hits	223	Target Neighborhood Hits	362	Shared Neighborhood Hits	108
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP7_HUMAN
NC score	0.691157 (rank : 26)	θ value	9.59137e-10 (rank : 23)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	72
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP51_HUMAN
NC score	0.689401 (rank : 27)	θ value	1.80886e-08 (rank : 30)
Query Neighborhood Hits	223	Target Neighborhood Hits	162	Shared Neighborhood Hits	78
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UB17L_HUMAN
NC score	0.687640 (rank : 28)	θ value	4.45536e-07 (rank : 45)
Query Neighborhood Hits	223	Target Neighborhood Hits	83	Shared Neighborhood Hits	70
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP3_HUMAN
NC score	0.684352 (rank : 29)	θ value	1.43324e-05 (rank : 53)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP47_HUMAN
NC score	0.681379 (rank : 30)	θ value	1.9326e-10 (rank : 21)
Query Neighborhood Hits	223	Target Neighborhood Hits	149	Shared Neighborhood Hits	76
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_MOUSE
NC score	0.680293 (rank : 31)	θ value	1.133e-10 (rank : 20)
Query Neighborhood Hits	223	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP42_HUMAN
NC score	0.675513 (rank : 32)	θ value	7.84624e-12 (rank : 14)
Query Neighborhood Hits	223	Target Neighborhood Hits	445	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP40_HUMAN
NC score	0.668724 (rank : 33)	θ value	4.0297e-08 (rank : 35)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP8_HUMAN
NC score	0.666205 (rank : 34)	θ value	2.36244e-08 (rank : 31)
Query Neighborhood Hits	223	Target Neighborhood Hits	751	Shared Neighborhood Hits	148
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP49_MOUSE
NC score	0.662060 (rank : 35)	θ value	1.99992e-07 (rank : 42)
Query Neighborhood Hits	223	Target Neighborhood Hits	91	Shared Neighborhood Hits	75
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP44_HUMAN
NC score	0.659466 (rank : 36)	θ value	4.0297e-08 (rank : 36)
Query Neighborhood Hits	223	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_HUMAN
NC score	0.651094 (rank : 37)	θ value	6.43352e-06 (rank : 51)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP24_HUMAN
NC score	0.648451 (rank : 38)	θ value	3.08544e-08 (rank : 33)
Query Neighborhood Hits	223	Target Neighborhood Hits	96	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP1_HUMAN
NC score	0.630847 (rank : 39)	θ value	8.40245e-06 (rank : 52)
Query Neighborhood Hits	223	Target Neighborhood Hits	259	Shared Neighborhood Hits	84
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP15_MOUSE
NC score	0.630498 (rank : 40)	θ value	6.21693e-09 (rank : 26)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP15_HUMAN
NC score	0.629986 (rank : 41)	θ value	4.76016e-09 (rank : 24)
Query Neighborhood Hits	223	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP4_HUMAN
NC score	0.626623 (rank : 42)	θ value	5.26297e-08 (rank : 37)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP34_MOUSE
NC score	0.625497 (rank : 43)	θ value	2.98157e-11 (rank : 17)
Query Neighborhood Hits	223	Target Neighborhood Hits	189	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.624526 (rank : 44)	θ value	2.98157e-11 (rank : 16)
Query Neighborhood Hits	223	Target Neighborhood Hits	210	Shared Neighborhood Hits	81
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP4_MOUSE
NC score	0.620987 (rank : 45)	θ value	1.99992e-07 (rank : 43)
Query Neighborhood Hits	223	Target Neighborhood Hits	90	Shared Neighborhood Hits	71
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP43_MOUSE
NC score	0.619730 (rank : 46)	θ value	1.43324e-05 (rank : 54)
Query Neighborhood Hits	223	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_HUMAN
NC score	0.619385 (rank : 47)	θ value	2.88788e-06 (rank : 49)
Query Neighborhood Hits	223	Target Neighborhood Hits	144	Shared Neighborhood Hits	72
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP11_HUMAN
NC score	0.619266 (rank : 48)	θ value	3.19293e-05 (rank : 56)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP31_HUMAN
NC score	0.613046 (rank : 49)	θ value	3.77169e-06 (rank : 50)
Query Neighborhood Hits	223	Target Neighborhood Hits	293	Shared Neighborhood Hits	80
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP30_HUMAN
NC score	0.579595 (rank : 50)	θ value	0.0113563 (rank : 66)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP14_HUMAN
NC score	0.575043 (rank : 51)	θ value	0.00298849 (rank : 62)
Query Neighborhood Hits	223	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

USP9Y_HUMAN
NC score	0.566184 (rank : 52)	θ value	0.000270298 (rank : 58)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	72
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP14_MOUSE
NC score	0.565156 (rank : 53)	θ value	0.00134147 (rank : 61)
Query Neighborhood Hits	223	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

USP9X_HUMAN
NC score	0.560219 (rank : 54)	θ value	0.000270298 (rank : 57)
Query Neighborhood Hits	223	Target Neighborhood Hits	161	Shared Neighborhood Hits	75
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.559494 (rank : 55)	θ value	0.000602161 (rank : 59)
Query Neighborhood Hits	223	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP32_HUMAN
NC score	0.558879 (rank : 56)	θ value	7.59969e-07 (rank : 47)
Query Neighborhood Hits	223	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP37_HUMAN
NC score	0.552485 (rank : 57)	θ value	1.87187e-05 (rank : 55)
Query Neighborhood Hits	223	Target Neighborhood Hits	208	Shared Neighborhood Hits	85
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP6_HUMAN
NC score	0.527848 (rank : 58)	θ value	9.92553e-07 (rank : 48)
Query Neighborhood Hits	223	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP10_MOUSE
NC score	0.524328 (rank : 59)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	223	Target Neighborhood Hits	150	Shared Neighborhood Hits	70
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_HUMAN
NC score	0.522046 (rank : 60)	θ value	0.00665767 (rank : 64)
Query Neighborhood Hits	223	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP28_HUMAN
NC score	0.509737 (rank : 61)	θ value	8.97725e-08 (rank : 41)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_MOUSE
NC score	0.509158 (rank : 62)	θ value	6.87365e-08 (rank : 40)
Query Neighborhood Hits	223	Target Neighborhood Hits	178	Shared Neighborhood Hits	72
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP25_MOUSE
NC score	0.491506 (rank : 63)	θ value	3.41135e-07 (rank : 44)
Query Neighborhood Hits	223	Target Neighborhood Hits	116	Shared Neighborhood Hits	74
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.490010 (rank : 64)	θ value	6.87365e-08 (rank : 39)
Query Neighborhood Hits	223	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP29_HUMAN
NC score	0.473295 (rank : 65)	θ value	0.0193708 (rank : 72)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_HUMAN
NC score	0.451081 (rank : 66)	θ value	0.00390308 (rank : 63)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP13_HUMAN
NC score	0.447290 (rank : 67)	θ value	0.00134147 (rank : 60)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	70
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP29_MOUSE
NC score	0.446412 (rank : 68)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	223	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP5_HUMAN
NC score	0.433523 (rank : 69)	θ value	0.0148317 (rank : 69)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	71
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
NC score	0.430753 (rank : 70)	θ value	0.0330416 (rank : 77)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	71
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

SNUT2_MOUSE
NC score	0.403574 (rank : 71)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	223	Target Neighborhood Hits	80	Shared Neighborhood Hits	59
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
NC score	0.394874 (rank : 72)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	223	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP26_MOUSE
NC score	0.359436 (rank : 73)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	71
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP53_HUMAN
NC score	0.125463 (rank : 74)	θ value	0.0193708 (rank : 73)
Query Neighborhood Hits	223	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP53_MOUSE
NC score	0.122501 (rank : 75)	θ value	0.0148317 (rank : 68)
Query Neighborhood Hits	223	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP54_MOUSE
NC score	0.100672 (rank : 76)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	223	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_HUMAN
NC score	0.100142 (rank : 77)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	223	Target Neighborhood Hits	21	Shared Neighborhood Hits	18
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

BRAP_MOUSE
NC score	0.091762 (rank : 78)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	223	Target Neighborhood Hits	409	Shared Neighborhood Hits	56
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRAP_HUMAN
NC score	0.085454 (rank : 79)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	223	Target Neighborhood Hits	560	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

NSBP1_HUMAN
NC score	0.073672 (rank : 80)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	223	Target Neighborhood Hits	251	Shared Neighborhood Hits	56
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PININ_HUMAN
NC score	0.073657 (rank : 81)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	223	Target Neighborhood Hits	753	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

NSBP1_MOUSE
NC score	0.073352 (rank : 82)	θ value	0.0252991 (rank : 74)
Query Neighborhood Hits	223	Target Neighborhood Hits	681	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PININ_MOUSE
NC score	0.072350 (rank : 83)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	223	Target Neighborhood Hits	777	Shared Neighborhood Hits	93
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PTMS_HUMAN
NC score	0.069090 (rank : 84)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	223	Target Neighborhood Hits	111	Shared Neighborhood Hits	37
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMA_MOUSE
NC score	0.068259 (rank : 85)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	223	Target Neighborhood Hits	73	Shared Neighborhood Hits	26
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

GGNB1_MOUSE
NC score	0.067472 (rank : 86)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	223	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

PTMA_HUMAN
NC score	0.066266 (rank : 87)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

CGRE1_MOUSE
NC score	0.065127 (rank : 88)	θ value	0.00869519 (rank : 65)
Query Neighborhood Hits	223	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

SEC63_HUMAN
NC score	0.064686 (rank : 89)	θ value	0.0330416 (rank : 76)
Query Neighborhood Hits	223	Target Neighborhood Hits	586	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

ALO17_HUMAN
NC score	0.063942 (rank : 90)	θ value	0.0961366 (rank : 81)
Query Neighborhood Hits	223	Target Neighborhood Hits	317	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

BSCL2_HUMAN
NC score	0.062495 (rank : 91)	θ value	0.21417 (rank : 89)
Query Neighborhood Hits	223	Target Neighborhood Hits	148	Shared Neighborhood Hits	18
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

AKA12_HUMAN
NC score	0.062449 (rank : 92)	θ value	0.62314 (rank : 102)
Query Neighborhood Hits	223	Target Neighborhood Hits	825	Shared Neighborhood Hits	79
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

IWS1_MOUSE
NC score	0.061834 (rank : 93)	θ value	0.0961366 (rank : 82)
Query Neighborhood Hits	223	Target Neighborhood Hits	1258	Shared Neighborhood Hits	73
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SEC63_MOUSE
NC score	0.061475 (rank : 94)	θ value	0.0431538 (rank : 78)
Query Neighborhood Hits	223	Target Neighborhood Hits	601	Shared Neighborhood Hits	55
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

ASPX_HUMAN
NC score	0.061397 (rank : 95)	θ value	0.0193708 (rank : 70)
Query Neighborhood Hits	223	Target Neighborhood Hits	148	Shared Neighborhood Hits	13
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

IWS1_HUMAN
NC score	0.060839 (rank : 96)	θ value	0.163984 (rank : 88)
Query Neighborhood Hits	223	Target Neighborhood Hits	1241	Shared Neighborhood Hits	76
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TCRG1_HUMAN
NC score	0.060080 (rank : 97)	θ value	0.125558 (rank : 85)
Query Neighborhood Hits	223	Target Neighborhood Hits	929	Shared Neighborhood Hits	71
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.059674 (rank : 98)	θ value	0.125558 (rank : 86)
Query Neighborhood Hits	223	Target Neighborhood Hits	947	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

RPGR1_MOUSE
NC score	0.058700 (rank : 99)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	223	Target Neighborhood Hits	713	Shared Neighborhood Hits	115
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

MDN1_HUMAN
NC score	0.057548 (rank : 100)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	223	Target Neighborhood Hits	662	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PTMS_MOUSE
NC score	0.057269 (rank : 101)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	223	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

ACINU_HUMAN
NC score	0.055474 (rank : 102)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	223	Target Neighborhood Hits	828	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BSCL2_MOUSE
NC score	0.054746 (rank : 103)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z2E9, Q810B0, Q9JJC2, Q9JMF1	Gene names	Bscl2, Gng3lg
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein homolog).

IF3A_MOUSE
NC score	0.053933 (rank : 104)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	223	Target Neighborhood Hits	871	Shared Neighborhood Hits	86
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IF3A_HUMAN
NC score	0.053367 (rank : 105)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	223	Target Neighborhood Hits	875	Shared Neighborhood Hits	84
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

DMP1_MOUSE
NC score	0.053226 (rank : 106)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	223	Target Neighborhood Hits	498	Shared Neighborhood Hits	66
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

TCAL5_HUMAN
NC score	0.052750 (rank : 107)	θ value	0.0193708 (rank : 71)
Query Neighborhood Hits	223	Target Neighborhood Hits	806	Shared Neighborhood Hits	51
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

NASP_HUMAN
NC score	0.052536 (rank : 108)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	223	Target Neighborhood Hits	709	Shared Neighborhood Hits	72
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

MDC1_MOUSE
NC score	0.052441 (rank : 109)	θ value	0.0330416 (rank : 75)
Query Neighborhood Hits	223	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

LEO1_HUMAN
NC score	0.052436 (rank : 110)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	223	Target Neighborhood Hits	958	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DMP1_HUMAN
NC score	0.052011 (rank : 111)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	223	Target Neighborhood Hits	491	Shared Neighborhood Hits	60
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

IF2P_HUMAN
NC score	0.051960 (rank : 112)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	223	Target Neighborhood Hits	889	Shared Neighborhood Hits	111
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

HDAC6_MOUSE
NC score	0.051526 (rank : 113)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

HDAC6_HUMAN
NC score	0.051319 (rank : 114)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	223	Target Neighborhood Hits	145	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

LEO1_MOUSE
NC score	0.050837 (rank : 115)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	223	Target Neighborhood Hits	946	Shared Neighborhood Hits	71
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

FA21C_HUMAN
NC score	0.050731 (rank : 116)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	223	Target Neighborhood Hits	194	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

GGNB1_HUMAN
NC score	0.050463 (rank : 117)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	223	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

MDC1_HUMAN
NC score	0.048391 (rank : 118)	θ value	0.0961366 (rank : 83)
Query Neighborhood Hits	223	Target Neighborhood Hits	1446	Shared Neighborhood Hits	66
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SPRL1_MOUSE
NC score	0.047922 (rank : 119)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	223	Target Neighborhood Hits	403	Shared Neighborhood Hits	49
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TCAL3_HUMAN
NC score	0.047188 (rank : 120)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	223	Target Neighborhood Hits	274	Shared Neighborhood Hits	24
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

CF010_HUMAN
NC score	0.046970 (rank : 121)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	223	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

PSMD2_MOUSE
NC score	0.046192 (rank : 122)	θ value	0.279714 (rank : 92)
Query Neighborhood Hits	223	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

MAP1B_MOUSE
NC score	0.045455 (rank : 123)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	223	Target Neighborhood Hits	977	Shared Neighborhood Hits	93
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

ERIC1_HUMAN
NC score	0.045425 (rank : 124)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	223	Target Neighborhood Hits	364	Shared Neighborhood Hits	32
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

NF2L3_HUMAN
NC score	0.045165 (rank : 125)	θ value	0.0563607 (rank : 79)
Query Neighborhood Hits	223	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

RSF1_HUMAN
NC score	0.044348 (rank : 126)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	223	Target Neighborhood Hits	539	Shared Neighborhood Hits	70
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

MINT_HUMAN
NC score	0.042962 (rank : 127)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	223	Target Neighborhood Hits	1291	Shared Neighborhood Hits	80
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYST3_MOUSE
NC score	0.042097 (rank : 128)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	223	Target Neighborhood Hits	688	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NPBL_MOUSE
NC score	0.041574 (rank : 129)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	223	Target Neighborhood Hits	1041	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MINT_MOUSE
NC score	0.040634 (rank : 130)	θ value	0.125558 (rank : 84)
Query Neighborhood Hits	223	Target Neighborhood Hits	1514	Shared Neighborhood Hits	66
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CCD11_HUMAN
NC score	0.039947 (rank : 131)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	223	Target Neighborhood Hits	822	Shared Neighborhood Hits	69
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

PSMD2_HUMAN
NC score	0.039678 (rank : 132)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	223	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	Q13200, Q12932, Q15321, Q96I12	Gene names	PSMD2, TRAP2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).

TCAL4_HUMAN
NC score	0.037733 (rank : 133)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	223	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q96EI5, Q8WY12, Q9H2H1, Q9H775	Gene names	TCEAL4
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 4 (TCEA-like protein 4) (Transcription elongation factor S-II protein-like 4).

SMC1A_HUMAN
NC score	0.036084 (rank : 134)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	223	Target Neighborhood Hits	1346	Shared Neighborhood Hits	84
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
NC score	0.036063 (rank : 135)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	223	Target Neighborhood Hits	1384	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

KMHN1_MOUSE
NC score	0.033807 (rank : 136)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	223	Target Neighborhood Hits	949	Shared Neighborhood Hits	66
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

TP53B_MOUSE
NC score	0.033802 (rank : 137)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	223	Target Neighborhood Hits	644	Shared Neighborhood Hits	40
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

NF2L3_MOUSE
NC score	0.033706 (rank : 138)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

CCD21_HUMAN
NC score	0.033326 (rank : 139)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	223	Target Neighborhood Hits	1228	Shared Neighborhood Hits	83
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

TAXB1_MOUSE
NC score	0.032842 (rank : 140)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	223	Target Neighborhood Hits	886	Shared Neighborhood Hits	62
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

SAFB2_HUMAN
NC score	0.032640 (rank : 141)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	223	Target Neighborhood Hits	720	Shared Neighborhood Hits	78
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

OPTN_HUMAN
NC score	0.032451 (rank : 142)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	223	Target Neighborhood Hits	827	Shared Neighborhood Hits	70
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

BRD8_MOUSE
NC score	0.032289 (rank : 143)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	223	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

NEST_HUMAN
NC score	0.031993 (rank : 144)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	223	Target Neighborhood Hits	1305	Shared Neighborhood Hits	96
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CCD46_MOUSE
NC score	0.031841 (rank : 145)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	223	Target Neighborhood Hits	1405	Shared Neighborhood Hits	84
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

TAXB1_HUMAN
NC score	0.031563 (rank : 146)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	223	Target Neighborhood Hits	829	Shared Neighborhood Hits	62
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

INVO_MOUSE
NC score	0.031512 (rank : 147)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	223	Target Neighborhood Hits	474	Shared Neighborhood Hits	54
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

RABE1_HUMAN
NC score	0.030723 (rank : 148)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	223	Target Neighborhood Hits	1104	Shared Neighborhood Hits	74
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

GOGA4_HUMAN
NC score	0.030617 (rank : 149)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	223	Target Neighborhood Hits	2034	Shared Neighborhood Hits	96
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

OXRP_HUMAN
NC score	0.030603 (rank : 150)	θ value	0.0563607 (rank : 80)
Query Neighborhood Hits	223	Target Neighborhood Hits	544	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

KNTC2_HUMAN
NC score	0.030514 (rank : 151)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	223	Target Neighborhood Hits	673	Shared Neighborhood Hits	54
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

PALB2_HUMAN
NC score	0.030483 (rank : 152)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

RABE1_MOUSE
NC score	0.030426 (rank : 153)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	223	Target Neighborhood Hits	1105	Shared Neighborhood Hits	74
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

OPTN_MOUSE
NC score	0.030360 (rank : 154)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	223	Target Neighborhood Hits	1120	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

DUS1L_HUMAN
NC score	0.030182 (rank : 155)	θ value	0.279714 (rank : 91)
Query Neighborhood Hits	223	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1R4, Q96AI3	Gene names	DUS1L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

PRG3_MOUSE
NC score	0.030071 (rank : 156)	θ value	0.21417 (rank : 90)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

GOGA4_MOUSE
NC score	0.029747 (rank : 157)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	223	Target Neighborhood Hits	1939	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_MOUSE
NC score	0.029187 (rank : 158)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	223	Target Neighborhood Hits	1434	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MYO5A_HUMAN
NC score	0.028705 (rank : 159)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	223	Target Neighborhood Hits	1092	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYH9_MOUSE
NC score	0.028702 (rank : 160)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	223	Target Neighborhood Hits	1829	Shared Neighborhood Hits	93
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CP250_HUMAN
NC score	0.028536 (rank : 161)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	223	Target Neighborhood Hits	1805	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MYH11_HUMAN
NC score	0.028260 (rank : 162)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	223	Target Neighborhood Hits	1806	Shared Neighborhood Hits	90
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MLL2_HUMAN
NC score	0.028170 (rank : 163)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	223	Target Neighborhood Hits	1788	Shared Neighborhood Hits	73
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYH11_MOUSE
NC score	0.027981 (rank : 164)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	223	Target Neighborhood Hits	1777	Shared Neighborhood Hits	88
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_HUMAN
NC score	0.027969 (rank : 165)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	223	Target Neighborhood Hits	1762	Shared Neighborhood Hits	89
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

GOGA5_HUMAN
NC score	0.027925 (rank : 166)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	223	Target Neighborhood Hits	1168	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

RB6I2_MOUSE
NC score	0.027898 (rank : 167)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	223	Target Neighborhood Hits	1433	Shared Neighborhood Hits	80
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

MYO5A_MOUSE
NC score	0.027897 (rank : 168)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	223	Target Neighborhood Hits	1117	Shared Neighborhood Hits	73
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYH10_HUMAN
NC score	0.027791 (rank : 169)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	223	Target Neighborhood Hits	1620	Shared Neighborhood Hits	84
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RRP5_HUMAN
NC score	0.027697 (rank : 170)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	223	Target Neighborhood Hits	291	Shared Neighborhood Hits	40
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

RB6I2_HUMAN
NC score	0.027628 (rank : 171)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	223	Target Neighborhood Hits	1584	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

LSP1_HUMAN
NC score	0.027545 (rank : 172)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	223	Target Neighborhood Hits	142	Shared Neighborhood Hits	19
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

CENPF_HUMAN
NC score	0.027506 (rank : 173)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	223	Target Neighborhood Hits	1932	Shared Neighborhood Hits	84
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CTGE5_MOUSE
NC score	0.027440 (rank : 174)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	223	Target Neighborhood Hits	928	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

SMRC1_MOUSE
NC score	0.027417 (rank : 175)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	223	Target Neighborhood Hits	459	Shared Neighborhood Hits	56
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

CNTRB_MOUSE
NC score	0.027401 (rank : 176)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	223	Target Neighborhood Hits	1029	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

BPAEA_HUMAN
NC score	0.027343 (rank : 177)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	223	Target Neighborhood Hits	1369	Shared Neighborhood Hits	82
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRD8_HUMAN
NC score	0.027283 (rank : 178)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	223	Target Neighborhood Hits	292	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

OSBL8_HUMAN
NC score	0.027086 (rank : 179)	θ value	0.365318 (rank : 95)
Query Neighborhood Hits	223	Target Neighborhood Hits	289	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

CROCC_HUMAN
NC score	0.026878 (rank : 180)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	223	Target Neighborhood Hits	1409	Shared Neighborhood Hits	75
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

STIM1_MOUSE
NC score	0.026365 (rank : 181)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	223	Target Neighborhood Hits	660	Shared Neighborhood Hits	48
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

RUFY1_MOUSE
NC score	0.025957 (rank : 182)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	223	Target Neighborhood Hits	765	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

FLIP1_HUMAN
NC score	0.025762 (rank : 183)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	223	Target Neighborhood Hits	1405	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

RIMB1_MOUSE
NC score	0.025697 (rank : 184)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	223	Target Neighborhood Hits	1376	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

STIM1_HUMAN
NC score	0.025448 (rank : 185)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	223	Target Neighborhood Hits	665	Shared Neighborhood Hits	47
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

BPA1_MOUSE
NC score	0.025032 (rank : 186)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	223	Target Neighborhood Hits	1477	Shared Neighborhood Hits	87
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TS101_MOUSE
NC score	0.024997 (rank : 187)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	223	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

RUFY2_HUMAN
NC score	0.024592 (rank : 188)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	223	Target Neighborhood Hits	1208	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

MYH13_HUMAN
NC score	0.024391 (rank : 189)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	223	Target Neighborhood Hits	1504	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

ADDB_MOUSE
NC score	0.023446 (rank : 190)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	223	Target Neighborhood Hits	574	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

PHLB1_HUMAN
NC score	0.022578 (rank : 191)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	223	Target Neighborhood Hits	1038	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

UACA_MOUSE
NC score	0.022516 (rank : 192)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	223	Target Neighborhood Hits	1620	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

TRAK1_HUMAN
NC score	0.022446 (rank : 193)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	223	Target Neighborhood Hits	660	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

PHF3_HUMAN
NC score	0.022306 (rank : 194)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	223	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

LIPB1_HUMAN
NC score	0.021778 (rank : 195)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	223	Target Neighborhood Hits	640	Shared Neighborhood Hits	50
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

TCAL7_HUMAN
NC score	0.021209 (rank : 196)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	223	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BRU2, Q96AT4	Gene names	TCEAL7
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 7 (TCEA-like protein 7) (Transcription elongation factor S-II protein-like 7).

ANR26_MOUSE
NC score	0.021140 (rank : 197)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	223	Target Neighborhood Hits	1554	Shared Neighborhood Hits	78
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

PHF20_MOUSE
NC score	0.020213 (rank : 198)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	223	Target Neighborhood Hits	513	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

AR13B_HUMAN
NC score	0.019863 (rank : 199)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	223	Target Neighborhood Hits	528	Shared Neighborhood Hits	35
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

LSP1_MOUSE
NC score	0.019200 (rank : 200)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	223	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	P19973, P97339, Q04950, Q62022, Q62023, Q62024, Q8CD28, Q99L65	Gene names	Lsp1, Pp52, S37, Wp34
Domain Architecture
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (S37 protein).

DMN_HUMAN
NC score	0.018805 (rank : 201)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	223	Target Neighborhood Hits	690	Shared Neighborhood Hits	64
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

CJ095_HUMAN
NC score	0.017963 (rank : 202)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	223	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

HASP_MOUSE
NC score	0.017689 (rank : 203)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	223	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

MATR3_HUMAN
NC score	0.017398 (rank : 204)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	223	Target Neighborhood Hits	325	Shared Neighborhood Hits	34
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NKTR_HUMAN
NC score	0.017021 (rank : 205)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	223	Target Neighborhood Hits	658	Shared Neighborhood Hits	48
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

JIP3_MOUSE
NC score	0.016980 (rank : 206)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	223	Target Neighborhood Hits	759	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MYRIP_HUMAN
NC score	0.014269 (rank : 207)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	223	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NSD1_MOUSE
NC score	0.013442 (rank : 208)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	223	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SRPK1_MOUSE
NC score	0.013287 (rank : 209)	θ value	0.365318 (rank : 96)
Query Neighborhood Hits	223	Target Neighborhood Hits	639	Shared Neighborhood Hits	16
SwissProt Accessions	O70551, O70193, Q99JT3	Gene names	Srpk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

SETB1_HUMAN
NC score	0.012674 (rank : 210)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	223	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

GASP1_HUMAN
NC score	0.011851 (rank : 211)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	223	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JY77, O43168, Q96LA1	Gene names	GPRASP1, GASP, KIAA0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

PSA5_HUMAN
NC score	0.011630 (rank : 212)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	223	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P28066, Q6IBF7	Gene names	PSMA5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).

PSA5_MOUSE
NC score	0.011630 (rank : 213)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	223	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2U1	Gene names	Psma5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).

SRPK1_HUMAN
NC score	0.011572 (rank : 214)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	223	Target Neighborhood Hits	706	Shared Neighborhood Hits	27
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TTF2_MOUSE
NC score	0.010275 (rank : 215)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	223	Target Neighborhood Hits	364	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

CLGN_MOUSE
NC score	0.010195 (rank : 216)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	223	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

ZCH11_HUMAN
NC score	0.010084 (rank : 217)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	223	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

TTC1_HUMAN
NC score	0.009485 (rank : 218)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	223	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

PRAM7_HUMAN
NC score	0.009084 (rank : 219)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	223	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VXH5	Gene names	PRAMEF7
Domain Architecture	No domain graphic available
Description	PRAME family member 7.

PRAM8_HUMAN
NC score	0.009079 (rank : 220)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	223	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VWM4	Gene names	PRAMEF8
Domain Architecture	No domain graphic available
Description	PRAME family member 8.

STK10_MOUSE
NC score	0.008962 (rank : 221)	θ value	1.06291 (rank : 114)
Query Neighborhood Hits	223	Target Neighborhood Hits	2132	Shared Neighborhood Hits	90
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

AL3A1_MOUSE
NC score	0.008670 (rank : 222)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	223	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	P47739, Q9R203	Gene names	Aldh3a1, Ahd-4, Ahd4, Aldh3, Aldh4
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (Dioxin-inducible aldehyde dehydrogenase 3).

AL3A1_HUMAN
NC score	0.008037 (rank : 223)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	223	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P30838, Q9BT37	Gene names	ALDH3A1, ALDH3
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (ALDHIII).

LIMA1_HUMAN
NC score	0.008005 (rank : 224)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	223	Target Neighborhood Hits	309	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

LAT1_MOUSE
NC score	0.006928 (rank : 225)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	223	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z127, Q9JMI4	Gene names	Slc7a5, Lat1
Domain Architecture
Description	Large neutral amino acids transporter small subunit 1 (L-type amino acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC).

ETV3_HUMAN
NC score	0.006405 (rank : 226)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	223	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ALDOB_HUMAN
NC score	0.005709 (rank : 227)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	223	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P05062, Q13741, Q13742	Gene names	ALDOB, ALDB
Domain Architecture
Description	Fructose-bisphosphate aldolase B (EC 4.1.2.13) (Liver-type aldolase).

KI13B_HUMAN
NC score	0.005324 (rank : 228)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	223	Target Neighborhood Hits	492	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

PEG3_MOUSE
NC score	0.005254 (rank : 229)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	223	Target Neighborhood Hits	1101	Shared Neighborhood Hits	46
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

MRCKA_HUMAN
NC score	0.005122 (rank : 230)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	223	Target Neighborhood Hits	1999	Shared Neighborhood Hits	74
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

GANAB_MOUSE
NC score	0.005086 (rank : 231)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	223	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

TRI17_MOUSE
NC score	0.004831 (rank : 232)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	223	Target Neighborhood Hits	620	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

POTE8_HUMAN
NC score	0.004569 (rank : 233)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	223	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

TEX14_MOUSE
NC score	0.004524 (rank : 234)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	223	Target Neighborhood Hits	1333	Shared Neighborhood Hits	53
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TAOK1_HUMAN
NC score	0.003735 (rank : 235)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	223	Target Neighborhood Hits	1734	Shared Neighborhood Hits	72
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

PP16A_HUMAN
NC score	0.002750 (rank : 236)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	223	Target Neighborhood Hits	340	Shared Neighborhood Hits	8
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ZKSC1_HUMAN
NC score	-0.001352 (rank : 237)	θ value	0.125558 (rank : 87)
Query Neighborhood Hits	223	Target Neighborhood Hits	949	Shared Neighborhood Hits	19
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

ZNF96_MOUSE
NC score	-0.002991 (rank : 238)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	223	Target Neighborhood Hits	749	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1D7	Gene names	Znf96, Zfp96
Domain Architecture
Description	Zinc finger protein 96 (Zfp-96).

WNK1_MOUSE
NC score	-0.003620 (rank : 239)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	223	Target Neighborhood Hits	1179	Shared Neighborhood Hits	21
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

CDKL5_HUMAN
NC score	-0.004368 (rank : 240)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	223	Target Neighborhood Hits	967	Shared Neighborhood Hits	16
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).